GO.Biological.Process	GO:0000122	negative.regulation.of.transcription.from.RNA.polymerase.II.promoter	1	1e-300	1e-300	1e-300	1.581508e+0	ARID1A,ARX,ASCL3,ATF2,ATN1,ATRX,AXIN1,BACH2,BAG3,BEND6,BHLHE40,BHLHE41,BMP6,BPTF,BRMS1,BRMS1L,CBX5,CC2D1B,CCNE1,CDX2,CELA1,CHD4,CIC,CNOT7,COPS2,CPEB3,CREM,CTNNBIP1,CTR9,CUX2,DACH1,DDIT3,DDX20,DICER1,DLL4,DLX1,DLX2,DMRT1,DNAJA3,DNMT1,DNMT3A,DRD3,EDNRB,EHMT1,EHMT2,EID1,ELANE,ENO1,EP300,ESR1,FASLG,FEZF1,FNIP1,FNIP2,FOXA2,FOXD3,FOXL2,FOXO3,FOXP2,FZD8,GATA3,GATA6,GFI1,GFI1B,GLI2,GLI3,GLIS2,GPS2,GSC,HDAC10,HELT,HIF1AN,HIST1H1C,HIST1H1D,HIST1H1E,HNF1B,HOXA7,HOXB13,HOXB3,HOXB4,HOXB8,HOXC8,HOXD8,HOXD9,IKZF5,IMPACT,INSM1,IRX1,IRX2,JAZF1,JDP2,JUND,KANK2,KDM2B,KLF11,KLF12,KLF5,KMT5A,LEF1,LMO1,MAFK,MAP2K5,MED1,MEF2C,MEIS2,MEN1,MITF,MLIP,MLX,MSC,MXI1,MYT1L,N4BP2L2,NACC2,NCOA2,NCOR1,NEDD4,NELFB,NELFE,NEUROG3,NFATC2,NFKB2,NIPBL,NKAP,NKX2-1,NKX6-1,NKX6-2,NODAL,NOTCH1,NR2C1,NR2E1,NR2E3,NR2F1,NR2F2,NR4A2,NR4A3,NR6A1,NRARP,OSR2,PAX6,PCGF6,PDX1,PEX2,PHF12,PIAS1,POU4F1,POU4F2,POU6F1,PPARG,PPID,PPM1A,PRDM13,PRDM14,PRDM16,PROX1,PROX2,PTCH1,PTPN2,RARB,RECQL5,RERE,RFC1,RIF1,RLIM,RPL10,RUNX3,RYBP,SALL1,SALL4,SATB1,SHH,SHOX2,SIN3A,SIX1,SMAD3,SMARCA2,SMARCA4,SMYD2,SOX18,SOX2,SOX6,SP2,SP3,SP5,SPDEF,SPEN,SREBF1,STAT1,STAT3,SUDS3,SUZ12,TAF3,TAF7,TBX2,TBX21,TCERG1,TCF7,TCF7L2,TENM2,TFAP2A,TFCP2L1,TGIF1,TP73,TPR,TRPV4,TSHZ1,TSHZ2,TSHZ3,UBA52,UBB,URI1,USP9X,VAX1,VLDLR,WT1,WWC1,XPO1,ZBTB18,ZBTB2,ZBTB4,ZBTB42,ZEB1,ZEB2,ZFHX3,ZFPM2,ZGLP1,ZGPAT,ZHX1,ZHX2,ZHX3,ZNF136,ZNF217,ZNF224,ZNF281,ZNF451,ZNF536,ZNF568	MammalFishAncestor	300
GO.Biological.Process	GO:0006366	transcription.from.RNA.polymerase.II.promoter	1	1e-300	1e-300	1e-300	1.521743e+0	AFF4,ARID3A,ARNT,ATF1,ATF2,BACH2,BARHL1,BARHL2,BATF,BHLHA15,BTF3,C5AR1,CCNC,CCNH,CCNT1,CDC40,CDK12,CDK8,CDX2,CEBPD,CEBPZ,CLOCK,COPS2,COPS5,CPSF1,CPSF3,CREB3L4,CSRNP1,CSRNP2,CSRNP3,CSTF2,CSTF3,CTDP1,CTR9,DACH1,DDIT3,DLX2,DLX5,DMRT1,DVL2,EBF3,ELK3,ELL,ELP4,EP300,ERCC2,ERCC6,ESR1,ESRRB,ESRRG,FLNA,FOS,FOXD1,FOXL2,FOXO3,FUBP1,GATA3,GATA6,GCM1,GFI1B,GLI2,GLI3,GLIS2,GMEB2,GRHL1,GSX1,GTF2A1L,GTF2A2,GTF2B,HMGA1,HNF4G,HOXA1,HOXA10,HOXA5,HOXA7,HOXB1,HOXB2,HOXB3,HOXB5,HOXB7,HOXC10,HOXC11,HOXC13,HOXC4,HOXD10,HOXD13,HOXD3,HOXD4,HOXD8,ICE1,ICE2,IER2,INTS1,INTS12,INTS14,INTS2,INTS7,IRF5,JUND,KAT2A,KLF11,KLF5,KMT2A,LDB1,LEF1,LHX1,LHX3,LHX4,LMO4,LSM10,MED1,MED12,MED13,MED14,MED15,MED16,MEF2B,MEF2C,MEIS1,MEIS2,MEIS3,MITF,MLXIP,MNAT1,MSC,MYBL1,MYCN,MYF5,MYF6,NABP2,NCOR1,NELFB,NELFE,NEUROD2,NEUROG3,NFATC1,NFATC2,NFE2L1,NFE2L2,NFKB2,NKRF,NKX2-8,NKX6-1,NOTCH1,NPPA,NR1I2,NR2C1,NR2C2AP,NR2E1,NR2E3,NR2F1,NR3C2,NR4A2,NR4A3,NR5A1,NR5A2,NR6A1,NUDT21,ONECUT1,ONECUT2,OTX1,OTX2,PAX1,PAX2,PAX3,PAX6,PAX9,PBX3,PBX4,PDX1,PHOX2B,PITX1,PITX2,PITX3,PLAGL2,POLR2A,POLR2E,POLR2K,POU3F2,POU4F1,POU4F2,POU4F3,POU6F2,PPARG,PPM1D,RARB,RBMX,RFX4,RORA,RPAP2,RPRD2,RUNX3,RXRB,SALL3,SALL4,SETD2,SHOX,SIX1,SIX2,SIX3,SIX4,SIX6,SMAD1,SNAPC4,SNAPC5,SNRPF,SOHLH2,SOX18,SOX2,SOX21,SREBF1,SRRM1,SSBP4,STAG1,STAT3,STAT5B,STON1-GTF2A1L,SUPT6H,TAF1,TAF11,TAF2,TAF3,TAF4,TAF5,TAF5L,TAF7,TAF7L,TARDBP,TCERG1,TCF12,TEAD1,TEF,TFAP2A,TFAP2E,TFAP4,TFCP2,TFDP1,TFEC,THOC2,THOC7,THRAP3,TMF1,TP73,UPF3B,WT1,YBX2,ZBTB17,ZEB2,ZFHX3,ZGLP1,ZIC1,ZNF136,ZNF143,ZNF516,ZNF76	MammalFishAncestor	300
GO.Biological.Process	GO:0007010	cytoskeleton.organization	1	1e-300	1e-300	1e-300	1.531563e+0	ABI1,ABRAXAS2,ACTA1,ACTB,ACTC1,ACTG1,ADD3,ADRA2A,AGFG1,AGRN,AKAP9,ANK2,ANK3,ARHGAP10,ARHGAP12,ARHGEF10,ARMC4,ARPC3,ARPC5L,ATP2C1,ATRX,ATXN7,AUTS2,AXIN1,BAIAP2,BAIAP2L1,BBS2,BCAS3,BCCIP,BRCA2,CAMSAP1,CAMSAP2,CAPN3,CASQ1,CC2D2A,CCDC187,CCDC39,CCDC6,CCDC63,CCSAP,CEP120,CEP135,CEP152,CEP192,CEP350,CETN3,CFAP46,CFAP74,CGNL1,CHD3,CLASP1,CLIP1,CNN2,CNP,CNTLN,CNTNAP1,COBLL1,CORO1C,CORO6,CORO7,CSNK1D,CTTN,CUL9,DAG1,DCLK2,DCTN2,DES,DIAPH1,DNAAF4,DNAH1,DNAH5,DNAH7,DNAH8,DNAJB6,DOCK1,DOCK7,DRC1,DST,DYNC1H1,ENSG00000258472,EPPK1,ERBIN,ERMN,EYA1,FARP2,FGD6,FHL3,FLII,FLNA,FLNB,FOPNL,FRY,FRYL,FSCN1,FSCN2,GABARAP,GAPDH,GCC2,GPSM2,HAUS1,HDGFL3,HTT,INA,INF2,INO80,INPPL1,IQGAP2,IQSEC1,IQSEC2,JMY,JUP,KIF23,KIF3A,KIF3B,KIT,KIZ,KLHL41,KRT18,KRT3,KRT4,KRT76,KRT8,LARP4,LIMCH1,LLGL1,LMOD2,LURAP1,MAP1A,MAP2,MAP3K20,MAP7D1,MAP7D3,MAPKAP1,MARK4,MAST2,MICAL2,MICALL2,MSRB1,MTCL1,MYBPC1,MYBPC2,MYBPC3,MYBPHL,MYH10,MYH11,MYH3,MYL2,MYO18A,MYOM1,MYOM2,MYOZ1,MYOZ2,MZT1,NAV1,NCKIPSD,NCOR1,NDE1,NDEL1,NEK2,NEK6,NEK7,NEURL1,NF1,NIN,NISCH,NUMA1,OBSCN,OBSL1,ODF2,PACSIN1,PAK1,PAK5,PAK6,PALLD,PALM,PARVA,PAX6,PCLO,PDGFRA,PDLIM4,PDZD8,PEX14,PI4KA,PIBF1,PKD2,PKP1,PLCE1,PLEK2,PPP1R9A,PPP2R3C,PREX1,PRKCZ,PROX1,PSRC1,PSTPIP2,QRICH1,RAB11A,RAF1,RAN,RANBP1,RANBP2,RHOA,RHOF,RND1,RNF19A,ROCK1,S1PR2,SDCCAG8,SETD2,SH3D19,SHANK1,SHH,SHROOM1,SHTN1,SIPA1L1,SIX4,SLAIN2,SLK,SPAG1,SPAG17,SPAG4,SPAG5,SPC25,SPICE1,SPIRE1,SPTA1,SPTAN1,SPTBN1,SPTBN2,SPTBN4,SSH1,SSH2,SSX2IP,STMN3,STRIP1,SWAP70,SYNE1,SYNE3,TBCE,TBCK,TCAP,TEKT2,TLN2,TMSB4X,TNIK,TNNT2,TPM1,TRPV4,TTLL5,TTLL6,TUBA4A,TUBA4B,TUBB4B,TUBD1,TUBE1,TUBG1,TUBG2,TUBGCP4,TUBGCP5,TUBGCP6,UBE2B,USH1C,USP33,VAMP4,VIL1,VILL,VPS54,WASF1,WASF3,WASHC1,WASL,WDPCP,WEE1,WHAMM,WIPF1,WRAP73,XIRP2,ZMYM2,ZMYM3,ZMYM4,ZMYND10,ZNF207,ZRANB1	MammalFishAncestor	300
GO.Biological.Process	GO:0009790	embryo.development	1	1e-300	1e-300	1e-300	1.492541e+0	AATF,ABI1,ACVR1,ACVR2A,ADAM10,ADM,AKT1,ALDH1A2,ALDH1A3,ALX3,AMBRA1,ANKRD11,APOB,ARFRP1,ARID1A,ARNT,ATM,ATP5A1,ATP7A,AXIN1,BBS5,BIRC6,BPTF,BRCA2,BTF3,C5orf42,CACNA1C,CC2D2A,CCDC39,CCNB2,CDX2,CENPU,CEP290,CHRNA9,COL11A1,COL12A1,COL1A1,COL2A1,COL4A2,COL4A3BP,COL7A1,CSF2,CTHRC1,CTR9,CUL4A,DLD,DLL4,DLX1,DLX2,DLX5,DLX6,DMRT2,DNAJB6,DNMT1,DNMT3A,DSCAML1,DUSP5,DVL2,DYNC2H1,ECE1,EDNRA,EHMT1,ELL,EN2,ENDOG,EP300,ERCC2,EVX1,EYA1,FBN1,FBN2,FBXW4,FGF8,FKBP8,FLT1,FN1,FOLR1,FOXA2,FOXB1,FOXD3,FOXL2,FOXN4,FRAS1,FZD6,GATA3,GATA6,GCM1,GDF7,GJA5,GJB6,GLI1,GLI2,GLI3,GLMN,GPI,GSC,HMX2,HMX3,HNF1B,HORMAD1,HOXA1,HOXA10,HOXA11,HOXA3,HOXA5,HOXA6,HOXA7,HOXB1,HOXB2,HOXB3,HOXB4,HOXB5,HOXB6,HOXB7,HOXB8,HOXB9,HOXC10,HOXC11,HOXC4,HOXC5,HOXC6,HOXC9,HOXD1,HOXD10,HOXD12,HOXD13,HOXD3,HOXD4,HOXD8,HOXD9,HYAL1,ID2,IFT122,IL3,INHBA,INSIG1,IRX1,IRX2,IRX3,IRX5,ITGB4,ITPK1,KAT2A,KDM2B,KDM6B,KDR,KEAP1,KIAA1217,KIDINS220,KIT,KITLG,KLHL12,KMT2A,KRT8,LAMA3,LAMB1,LDB1,LEF1,LHX1,LIAS,LMBR1,LMO4,LMX1B,LNPK,LRP2,MAB21L2,MAP2K1,MAP3K20,MED1,MED12,MEF2C,MEGF8,MFN2,MIB1,MICAL2,MKKS,MMP2,MYCN,MYF5,MYF6,MYH3,MYO15A,MYO1E,MYO3A,MYO3B,MYO7A,NAGLU,NDEL1,NEK2,NF1,NIPBL,NODAL,NOLC1,NOTCH1,NPHP3,NR2F2,NR4A3,NR5A2,NRARP,NTN1,NUP133,OSR2,OTX1,OTX2,PAX1,PAX2,PAX6,PCSK5,PDGFRA,PDX1,PDZD7,PIK3CB,PITX1,PITX2,PKD1,PKD2,PLCD1,PLCG1,PLXNB2,POFUT1,POLE,POU4F3,PPP2R3A,PRDM14,PRKACB,PRKDC,PRKRA,PROX1,PTCH1,RARB,RASA1,RBBP6,RBP4,RCN1,RESP18,RPGRIP1L,RPL10,RYR2,SALL1,SALL4,SEC24C,SEC24D,SEMA3F,SETD2,SF3B6,SFRP2,SHH,SHOX2,SIN3A,SIX1,SIX2,SIX3,SIX4,SLC30A1,SLC39A1,SLC44A4,SMAD1,SMAD3,SMAD6,SOX18,SOX2,SOX6,SP3,SP8,SP9,STK3,SULF1,SULF2,SUPT20H,SYF2,TBX1,TBX2,TBX4,TCAP,TCF7,TCTN1,TEAD1,TENM4,TET1,TFAP2A,TGFB3,THOC2,TOP1,TPM1,TPO,TRIP12,TSC1,TSC2,TSHZ1,TWSG1,UBE2B,UBR3,UGDH,USH1C,VASH1,WDPCP,WDR19,WDR48,WNT2,WNT7A,WT1,ZBTB17,ZEB1,ZEB2,ZFPM2,ZIC1,ZNF281,ZNF568	MammalFishAncestor	300
GO.Biological.Process	GO:0060850	regulation.of.transcription.involved.in.cell.fate.commitment	1	1e-300	1e-300	1e-300	5.200026e+0	CHD5,DLX1,DLX2,EVX1,NKX6-1,NKX6-2,NR2F2,PAX6,PPARG,PROX1,RORA	MammalFishAncestor	300
GO.Biological.Process	GO:0048598	embryonic.morphogenesis	6	3.858153e-317	4.983576e-313	8.305961e-314	1.546604e+0	ACVR1,ACVR2A,ADM,ALDH1A2,ALDH1A3,ALX3,ARFRP1,ARID1A,AXIN1,BBS5,C5orf42,CACNA1C,CC2D2A,CCDC39,CEP290,CHRNA9,COL11A1,COL12A1,COL2A1,COL4A2,COL7A1,CTHRC1,CTR9,DLD,DLL4,DLX2,DLX5,DLX6,DNAJB6,DSCAML1,DUSP5,DVL2,DYNC2H1,ECE1,EYA1,FBN1,FBN2,FBXW4,FGF8,FLT1,FN1,FOLR1,FOXA2,FOXL2,FOXN4,FRAS1,FZD6,GATA3,GATA6,GCM1,GDF7,GJA5,GJB6,GLI1,GLI2,GLI3,GLMN,GPI,GSC,HMX2,HMX3,HNF1B,HOXA1,HOXA10,HOXA11,HOXA3,HOXA5,HOXA6,HOXA7,HOXB1,HOXB2,HOXB3,HOXB4,HOXB5,HOXB6,HOXB7,HOXB8,HOXC10,HOXC11,HOXC4,HOXC9,HOXD10,HOXD12,HOXD13,HOXD3,HOXD4,HOXD9,HYAL1,ID2,IFT122,INHBA,INSIG1,IRX1,IRX2,IRX3,IRX5,ITGB4,KAT2A,KDM2B,KDM6B,LAMA3,LAMB1,LDB1,LEF1,LHX1,LIAS,LMBR1,LMO4,LNPK,LRP2,MAB21L2,MAP3K20,MED1,MED12,MEF2C,MEGF8,MIB1,MICAL2,MKKS,MMP2,MYCN,MYF5,MYH3,MYO15A,MYO3A,MYO3B,MYO7A,NAGLU,NIPBL,NODAL,NOTCH1,NPHP3,NR4A3,NTN1,OSR2,OTX1,OTX2,PAX2,PAX6,PDGFRA,PDX1,PDZD7,PITX1,PITX2,PKD2,PLXNB2,POU4F3,PRKACB,PRKRA,PROX1,PTCH1,RARB,RBP4,RPGRIP1L,RYR2,SALL1,SALL4,SETD2,SFRP2,SHH,SHOX2,SIX1,SIX2,SIX3,SIX4,SLC39A1,SLC44A4,SMAD1,SMAD3,SOX18,SOX2,SP3,SP8,SP9,STK3,SUPT20H,SYF2,TBX1,TBX2,TBX4,TCAP,TCF7,TCTN1,TENM4,TFAP2A,TGFB3,TSC1,TSC2,TSHZ1,TWSG1,UGDH,USH1C,WDPCP,WDR19,WNT7A,ZBTB17,ZEB1,ZEB2,ZIC1,ZNF281,ZNF568	MammalFishAncestor	300
GO.Biological.Process	GO:0045165	cell.fate.commitment	7	3.673744e-311	4.745375e-307	6.779107e-308	1.783375e+0	ACVR1,ARX,AXIN1,BARHL2,BATF,CHD5,CTR9,CYLD,DBX1,DLL4,DLX1,DLX2,DMRT3,DOCK7,DSCAML1,EVX1,EYA1,FGF8,FKBP8,FOXA2,FOXN4,GATA3,GATA6,GCM1,GDF7,GLI2,GLI3,GSC,GSX1,GSX2,HNF1B,HOXA11,HOXC10,HOXD10,ID2,ISL2,JAG1,KDM6B,LHX3,MCL1,MEF2C,MNX1,MYF5,MYF6,MYL2,MYT1L,NKX2-1,NKX2-2,NKX6-1,NKX6-2,NODAL,NOTCH1,NR2E1,NR2F2,ONECUT1,ONECUT2,PAX2,PAX6,PITX1,POU3F2,POU4F1,POU6F2,PPARG,PPDPF,PRDM14,PRKDC,PROX1,PTCH1,RAB10,RORA,SHH,SIX1,SIX2,SMAD1,SOX18,SOX2,SOX6,STAT3,TBR1,TBX1,TBX2,TCF7L2,TENM4,WNT2,WNT2B,WNT5B,WNT7A,WT1,ZNF521	MammalFishAncestor	306.324
GO.Biological.Process	GO:0007423	sensory.organ.development	8	3.409038e-306	4.403454e-302	5.504318e-303	1.550458e+0	ABCB5,ACTL6A,ALDH1A2,ALDH1A3,ARID1A,ATP8B1,AXIN1,BMP6,BNC2,C12orf57,CACNA1C,CC2D2A,CDH23,CEBPD,CEP290,CHRNA9,CLCN2,CLIC4,COL11A1,COL2A1,COL4A1,CRB1,CRYBA1,CRYGA,CRYGB,CRYGD,CTHRC1,DLX5,DLX6,DVL2,ECE1,ESRRB,EYA1,FASLG,FAT4,FBN1,FBN2,FGF20,FGF8,FKBP8,FOXL2,FOXN4,FOXP2,FREM2,FSCN2,FZD6,GABRB2,GATA3,GJA8,GJB2,GJB6,GLI2,GLI3,GNAT1,GNAT2,GNB1,GPD2,GSC,HMX2,HMX3,HOXA1,HOXC13,IFT122,IMPDH2,INHBA,INSIG1,IRX5,JAG1,KDM2B,KDM5B,KIT,LAMB2,LEF1,LHX1,LHX3,LIN7A,LPCAT1,LRTOMT,MAB21L1,MAB21L2,MED1,MEGF11,MEIS1,MEIS2,MFN2,MIP,MYF5,MYO15A,MYO3A,MYO3B,MYO7A,MYOM1,MYOM2,NAGLU,NF1,NIPBL,NKD1,NOTCH1,NR2E1,NR2E3,NR4A3,NTN1,OSR2,OTX1,PAPD4,PAX2,PAX6,PDE6C,PDGFRA,PDZD7,PHOX2B,PITX2,PITX3,POU4F2,POU4F3,PRDM16,PRKRA,PROX1,PROX2,RAB11FIP4,RAB18,RARB,RBP4,RCN1,RHO,ROR1,RPGRIP1L,RS1,SALL1,SDHAF4,SDK1,SDK2,SERPINF1,SHH,SIX1,SIX2,SIX3,SIX4,SIX6,SLC26A5,SLC39A5,SLC44A4,SMAD3,SMARCA4,SMARCD3,SMCHD1,SOX2,SP3,SPARC,STAT3,STOX1,TBX1,TBX2,TCAP,TENM3,TFAP2A,TGFB3,TSHZ1,TTLL5,TUB,TWSG1,USH1C,USH2A,VAX1,WDPCP,WDR19,WNT2,WNT2B,WNT5B,WNT7A,WT1,XRN2,ZEB1,ZIC1	MammalFishAncestor	301.356
GO.Biological.Process	GO:0021514	ventral.spinal.cord.interneuron.differentiation	9	9.944039e-299	1.284472e-294	1.427191e-295	4.384983e+0	DBX1,DLL4,DMRT3,EVX1,FOXN4,GLI2,GLI3,LHX3,LMO4,NKX2-2,NKX6-1,NKX6-2,PAX6	MammalFishAncestor	293.891
GO.Biological.Process	GO:0007389	pattern.specification.process	10	1.082188e-277	1.397862e-273	1.397862e-274	1.613580e+0	ABI1,ACVR1,ACVR2A,ALDH1A2,ALG5,ALX3,ARMC4,ATM,AXIN1,BBS5,BPTF,CC2D2A,CCDC39,CDX2,CELSR2,CHSY1,CRKL,CTNNBIP1,DAW1,DBX1,DDIT3,DLL4,DLX1,DLX2,DMRT3,DNAAF4,DNAH11,DNAH5,DPCD,DRC1,DSCAML1,DVL2,DYNC2H1,DYNC2LI1,EMX2,EP300,EVX1,EYA1,FEZF1,FGF8,FKBP8,FOLR1,FOXA2,FOXB1,FOXD1,FOXN4,GALNT11,GLI1,GLI2,GLI3,GSC,GSX2,HHIP,HNF1B,HOXA10,HOXA11,HOXA3,HOXA5,HOXA6,HOXA7,HOXB1,HOXB2,HOXB3,HOXB4,HOXB5,HOXB6,HOXB7,HOXB8,HOXB9,HOXC10,HOXC11,HOXC13,HOXC4,HOXC5,HOXC6,HOXC8,HOXC9,HOXD10,HOXD11,HOXD12,HOXD13,HOXD3,HOXD4,HOXD8,HOXD9,IFT122,IRX1,IRX2,IRX3,IRX4,KAT2A,KDM2B,KIF3B,KMT2A,LDB1,LEF1,LHX1,LHX3,LMX1B,LRP2,MED12,MEF2C,MEGF8,MIB1,MICAL2,MKKS,MMP21,MNS1,MYF5,MYF6,NKX2-1,NKX2-2,NKX6-1,NKX6-2,NODAL,NOTCH1,NPHP3,NR2F2,NRARP,OFD1,OTX1,OTX2,PAX1,PAX2,PAX6,PBX3,PCSK5,PITX2,PKD2,POFUT1,PRKDC,PTCH1,RELN,RFX4,RNF111,RPGRIP1L,SEMA3F,SFRP2,SHH,SIX1,SIX2,SIX3,SMAD1,SMAD3,SMAD6,SMARCD3,SOX18,SP8,TBR1,TBX1,TBX2,TCAP,TCTN1,TSHZ1,TTC21B,TTC8,UNCX,WDR19,WNT2B,WNT7A,WT1,ZEB1,ZEB2,ZIC1	MammalFishAncestor	272.855
GO.Biological.Process	GO:0003002	regionalization	11	2.850740e-257	3.682301e-253	3.347546e-254	1.672618e+0	ABI1,ACVR2A,ALDH1A2,ATM,AXIN1,BPTF,CDX2,CELSR2,CHSY1,CRKL,CTNNBIP1,DBX1,DDIT3,DLL4,DLX1,DLX2,DMRT3,DPCD,DSCAML1,DVL2,DYNC2H1,EMX2,EP300,EVX1,FEZF1,FGF8,FKBP8,FOXA2,FOXB1,FOXD1,FOXN4,GLI1,GLI2,GLI3,GSC,GSX2,HHIP,HNF1B,HOXA10,HOXA11,HOXA3,HOXA5,HOXA6,HOXA7,HOXB1,HOXB2,HOXB3,HOXB4,HOXB5,HOXB6,HOXB7,HOXB8,HOXB9,HOXC10,HOXC11,HOXC13,HOXC4,HOXC5,HOXC6,HOXC8,HOXC9,HOXD10,HOXD11,HOXD13,HOXD3,HOXD4,HOXD8,HOXD9,IFT122,IRX1,IRX2,IRX3,KAT2A,KDM2B,KMT2A,LDB1,LEF1,LHX1,LHX3,LMX1B,LRP2,MED12,MEF2C,MEGF8,MIB1,MNS1,MYF5,MYF6,NKX2-1,NKX2-2,NKX6-1,NKX6-2,NODAL,NOTCH1,NR2F2,NRARP,OTX1,OTX2,PAX1,PAX2,PAX6,PBX3,PCSK5,PITX2,POFUT1,PRKDC,PTCH1,RELN,RFX4,RPGRIP1L,SEMA3F,SFRP2,SHH,SIX2,SIX3,SMAD3,SMAD6,SMARCD3,SP8,TBR1,TBX1,TCAP,TCTN1,TSHZ1,TTC21B,WDR19,WNT2B,WNT7A,WT1,ZEB2	MammalFishAncestor	252.434
GO.Biological.Process	GO:0046827	positive.regulation.of.protein.export.from.nucleus	12	2.473027e-256	3.194409e-252	2.662007e-253	6.449467e+0	BAG3,EMD,GAS6,GSK3B,PPM1A,SFN,TCF7L2,TPR,XPO4	MammalFishAncestor	251.496
GO.Biological.Process	GO:0016032	viral.process	13	4.253220e-255	5.493884e-251	4.226065e-252	1.661307e+0	ABCE1,ABI1,ATG7,BTRC,CALCOCO2,CAMLG,CBX5,CCNT1,CD4,CENPU,COPB1,CRTC1,CRTC2,CTBP2,CUL2,CUL4A,DAG1,DDX3X,DDX6,DENR,DERL1,DHX58,DHX9,DPP4,DYNC1I2,EIF2AK4,EIF3G,EIF4G1,EIF4G3,EP300,ERCC2,EXOC1,FKBP8,GAS6,GBF1,GFI1,GTF2A2,GTF2B,GYPA,HMGA1,HNRNPA1,HTATIP2,HTATSF1,HYAL2,ICAM1,IDE,IFIH1,ITGB6,IVNS1ABP,KAT2A,KDM4A,KDR,KIN,KLC1,KPNA2,KPNA4,KRT18,KRT8,LAMP1,LAMTOR5,LDLR,LMBRD1,MAGI3,MCTS1,MDFIC,MORC3,MSH6,MVB12B,NEDD4,NFKBIA,NUP133,NUP188,NUP210,NUP214,NUP93,PCSK5,PDGFRA,PDZD8,PI4KA,PLCG1,POLA1,POLR2E,PPIA,PPID,PSIP1,PSMA7,PSMB2,PSMB7,PSMB8,PSMB9,PTBP1,RAB11FIP4,RAB1B,RAN,RANBP1,RANBP2,RBM15,RBX1,RHOA,RNF216,RPL10,RPL19,RPL21,RPL22,RPL27A,RPL30,RPL32,RPL35,RPL39,RPL4,RPL41,RPL5,RPL9,RPLP1,RPS10,RPS15,RPS2,RPS26,RPS3A,SATB1,SEH1L,SELPLG,SEPT6,SERINC5,SET,SIVA1,SLC1A5,SLC25A4,SMAD3,SPEN,SSB,STAT1,STAT3,SUPT6H,SYNCRIP,TAF1,TAF4,TAF5,TANK,TAP1,TBKBP1,THOC2,THOC7,TMEM250,TNPO1,TOP1,TP73,TPR,TRAM1,TSC2,TYRO3,UBA52,UBB,UBR4,UCKL1,UNG,VDAC1,VPS37A,VPS37B,WDR48,XPO1,ZC3H7B,ZMYND11	MammalFishAncestor	250.26
GO.Biological.Process	GO:0021513	spinal.cord.dorsal/ventral.patterning	14	1.429246e-252	1.846157e-248	1.318684e-249	3.791912e+0	DBX1,DLL4,DMRT3,EVX1,FOXN4,GLI2,GLI3,IFT122,LHX3,NKX2-2,NKX6-1,NKX6-2,PAX6,RFX4,SHH	MammalFishAncestor	247.734
GO.Biological.Process	GO:0021511	spinal.cord.patterning	15	2.043393e-249	2.639451e-245	1.759634e-246	3.649910e+0	DBX1,DLL4,DMRT3,EVX1,FOXN4,GLI2,GLI3,IFT122,LHX3,NKX2-2,NKX6-1,NKX6-2,PAX6,RELN,RFX4,SHH	MammalFishAncestor	244.578
GO.Biological.Process	GO:0009124	nucleoside.monophosphate.biosynthetic.process	16	2.741115e-248	3.540698e-244	2.212936e-245	3.182136e+0	ADK,ADSS,ADSSL1,AK5,AK9,AMPD2,AMPD3,APRT,ATIC,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP5S,ATP6V0A1,ATP6V0A2,DCTD,DUT,ENTPD8,IMPDH2,LHPP,PAICS,PPAT,PRPS2,RFK,SLC25A13,STOML2,UCKL1,UMPS,UPP2	MammalFishAncestor	243.451
GO.Biological.Process	GO:0048646	anatomical.structure.formation.involved.in.morphogenesis	17	4.509226e-243	5.824567e-239	3.426216e-240	1.395741e+0	ABI1,ACTA1,ACTC1,ACTG1,ACVR1,ADAM12,ADAM17,ADGRB3,ADIPOR2,ADM,AGFG1,AIMP1,ALDH1A3,ANGPTL3,ANGPTL6,ANK2,ANXA2,ARHGAP22,ARHGAP24,ARID1A,ATF2,ATM,ATP5B,ATP7A,ATP8B1,AXIN1,BCAS3,C16orf45,CAPN3,CASQ1,CC2D2A,CCDC136,CDX2,CEP290,CLIC4,CNTNAP1,COL11A1,COL12A1,COL1A1,COL2A1,COL4A1,COL4A2,COL7A1,CSF3R,CSPG4,CTHRC1,CTR9,DAG1,DCSTAMP,DICER1,DLL4,DLX5,DLX6,DUSP5,DVL2,ECM1,EDAR,EDNRA,ELK3,ENPEP,EP300,ERCC2,EYA1,FAP,FBN2,FGF8,FIG4,FLT1,FN1,FOLR1,FOXA2,FOXB1,FOXD1,FOXN4,FZD6,FZD8,GATA3,GATA6,GDF7,GJA5,GLI2,GLI3,GLMN,GNPAT,GPI,GPX1,GSC,HERC1,HNF1B,HOXA1,HOXA11,HOXA3,HOXA7,HOXB1,HOXB13,HOXB3,HPSE,HSPG2,HTATIP2,IFT122,INHBA,IRX1,IRX2,IRX3,ITGA6,ITGB1BP1,ITGB4,JAG1,KAT2A,KDM2B,KDM6B,KDR,KLF5,KLHL12,KLHL41,KNDC1,KRT8,LAMA3,LAMB1,LDB1,LEF1,LEPR,LHX1,LIAS,LMO4,LMOD2,LRP2,MAP2K1,MED1,MED12,MEF2C,MEGF11,MEIS1,MFN2,MIB1,MMP2,MPP5,MYBPC1,MYBPC2,MYBPC3,MYBPHL,MYF5,MYF6,MYH11,MYH3,MYL2,MYOM1,MYOM2,MYOZ1,MYOZ2,NFKB2,NKX2-1,NODAL,NOLC1,NOS1,NOTCH1,NOV,NOX1,NR2E1,NR4A3,NRARP,NRCAM,NRP2,OBSCN,OBSL1,OTULIN,OTX2,PARVA,PAX1,PAX2,PAX6,PDE3B,PDGFRA,PGF,PHOX2A,PIK3CB,PIK3R6,PIKFYVE,PITX2,PLCD1,PLXNB2,PLXND1,POFUT1,PPP3CB,PRDM14,PRKACB,PRKCA,PRKD2,PRKDC,PROK1,PROK2,PROX1,PROX2,PTCH1,PTGS2,PTPN14,PTPN6,RBM15,RBP4,RELN,RHOB,RNF213,RORA,RS1,SALL1,SALL4,SBNO2,SDCCAG8,SDK1,SDK2,SETD2,SF3B6,SFRP2,SH3PXD2A,SHH,SIX1,SIX2,SIX4,SLC44A4,SMAD1,SMAD3,SMARCD3,SOX18,SOX2,SP3,SPEM1,STK3,TANC1,TBR1,TBX1,TBX2,TBX4,TCAP,TCTA,TCTN1,TENM4,TET1,TFAP2A,TGFBR3,TMF1,TNFSF12,TPM1,TSC1,TSC2,TWSG1,TXNDC8,UNC13D,VASH1,VPS33A,WDR72,WNT7A,WT1,ZEB2,ZNF304	MammalFishAncestor	238.235
GO.Biological.Process	GO:0044403	symbiosis,.encompassing.mutualism.through.parasitism	18	8.928169e-242	1.153252e-237	6.406953e-239	1.604319e+0	ABCE1,ABI1,ANXA2,ATG7,AZU1,BTRC,CALCOCO2,CAMLG,CBX5,CCNT1,CD4,CENPU,COPB1,CRTC1,CRTC2,CTBP2,CTDP1,CUL2,CUL4A,DAG1,DDX3X,DDX6,DENR,DERL1,DHX58,DHX9,DPP4,DYNC1I2,EIF2AK4,EIF3G,EIF4G1,EIF4G3,ELANE,EP300,ERCC2,EXOC1,FKBP8,FN1,GAPDH,GAS6,GBF1,GFI1,GPX1,GTF2A2,GTF2B,GYPA,HMGA1,HNRNPA1,HTATIP2,HTATSF1,HYAL2,ICAM1,IDE,IFIH1,ITGB6,IVNS1ABP,KAT2A,KDM4A,KDR,KIN,KLC1,KPNA2,KPNA4,KRT18,KRT8,LAMP1,LAMTOR5,LDLR,LEF1,LMBRD1,MAGI3,MCTS1,MDFIC,MET,MORC3,MSH6,MVB12B,NEDD4,NFKBIA,NUP133,NUP188,NUP210,NUP214,NUP93,PCSK5,PDGFRA,PDZD8,PI4KA,PLCG1,POLA1,POLR2E,PPIA,PPID,PSIP1,PSMA7,PSMB2,PSMB7,PSMB8,PSMB9,PTBP1,RAB11FIP4,RAB1B,RAB9A,RAN,RANBP1,RANBP2,RBM15,RBX1,RHOA,RNF216,RPL10,RPL19,RPL21,RPL22,RPL27A,RPL30,RPL32,RPL35,RPL39,RPL4,RPL41,RPL5,RPL9,RPLP1,RPS10,RPS15,RPS2,RPS26,RPS3A,SATB1,SEH1L,SELPLG,SEPT6,SERINC5,SET,SIVA1,SLC1A5,SLC25A4,SMAD3,SMARCA4,SMC3,SPEN,SSB,STAT1,STAT3,SUPT6H,SYNCRIP,TAF1,TAF11,TAF4,TAF5,TANK,TAP1,TARDBP,TBKBP1,TFAP4,THOC2,THOC7,TMEM250,TNPO1,TOP1,TP73,TPR,TRAM1,TSC2,TUSC2,TYRO3,UBA52,UBB,UBR4,UCKL1,ULK1,UNG,VDAC1,VPS37A,VPS37B,WDR48,XPO1,ZC3H7B,ZMYND11	MammalFishAncestor	236.938
GO.Biological.Process	GO:0061061	muscle.structure.development	19	2.188148e-240	2.826431e-236	1.487595e-237	1.546409e+0	ACTA1,ACTC1,ACTG1,ACVR1,ADAM12,ADGRB3,ADM,AKT1,ANK2,ARID1A,ASB2,ATP2A2,AXIN1,BCL9,BCL9L,CAPN3,CASQ1,CHRNA1,CHRNB1,COL11A1,COL19A1,COPS2,DLL4,DNER,DTYMK,EDNRB,EMD,EP300,FHL1,FHL3,FLNB,FLNC,FOS,FOXK1,FOXL2,FOXN2,FOXP2,FXR1,GATA6,GLMN,GPX1,GSC,GTF3C5,H3F3B,HMGCR,HOMER1,HOXD10,HOXD9,ITGB1BP2,JAG1,KAT2A,KDM6B,KLF5,KLHL40,KLHL41,KRT8,LAMA2,LEF1,LMOD2,LRP2,MAPK12,MED1,MEF2B,MEF2C,MKX,MSC,MTOR,MYBPC1,MYBPC2,MYBPC3,MYBPHL,MYEF2,MYF5,MYF6,MYH11,MYH3,MYL2,MYL6B,MYOM1,MYOM2,MYOZ1,MYOZ2,NEB,NEURL1,NEXN,NF1,NFATC2,NKD1,NOS1,NOTCH1,NPNT,NPPA,NPPB,NR2F2,OBSCN,OBSL1,P2RX2,PAX3,PDGFRA,PHOX2B,PITX1,PITX2,POU4F1,POU6F1,PROX1,PROX2,RARB,RNF165,RORA,RYR1,RYR2,SDC1,SGCA,SGCE,SGCG,SHH,SHOX2,SIX1,SIX4,SMARCD3,SORT1,SOX6,SPAG9,SPEG,SRI,SRPK3,STAC3,SYNE1,TANC1,TAZ,TBX1,TBX2,TCAP,TCF12,TCF7L2,TGFBR3,TNNC1,TNNI1,TNNT2,TPM1,TRIM54,TSC1,UBE4B,UTRN,VAX1,WFIKKN2,WNT2,WT1,XIRP2,ZBTB18,ZBTB42,ZFHX3,ZFPM2	MammalFishAncestor	235.549
GO.Biological.Process	GO:0044764	multi-organism.cellular.process	20	1.010867e-239	1.305737e-235	6.528685e-237	1.632922e+0	ABCE1,ABI1,ATG7,BTRC,CALCOCO2,CAMLG,CBX5,CCNT1,CD4,CENPU,COPB1,CRTC1,CRTC2,CTBP2,CUL2,CUL4A,DAG1,DDX3X,DDX6,DENR,DERL1,DHX58,DHX9,DPP4,DYNC1I2,EIF2AK4,EIF3G,EIF4G1,EIF4G3,EP300,ERCC2,EXOC1,FKBP8,GAS6,GBF1,GFI1,GTF2A2,GTF2B,GYPA,HMGA1,HNRNPA1,HTATIP2,HTATSF1,HYAL2,ICAM1,IDE,IFIH1,ITGB6,IVNS1ABP,KAT2A,KDM4A,KDR,KIN,KLC1,KPNA2,KPNA4,KRT18,KRT8,LAMP1,LAMTOR5,LDLR,LMBRD1,MAGI3,MCTS1,MDFIC,MORC3,MSH6,MVB12B,NEDD4,NFKBIA,NUP133,NUP188,NUP210,NUP214,NUP93,PCSK5,PDGFRA,PDZD8,PI4KA,PLCG1,POLA1,POLR2E,PPIA,PPID,PSIP1,PSMA7,PSMB2,PSMB7,PSMB8,PSMB9,PTBP1,RAB11FIP4,RAB1B,RAN,RANBP1,RANBP2,RBM15,RBX1,RHOA,RNF216,ROMO1,RPL10,RPL19,RPL21,RPL22,RPL27A,RPL30,RPL32,RPL35,RPL39,RPL4,RPL41,RPL5,RPL9,RPLP1,RPS10,RPS15,RPS2,RPS26,RPS3A,SATB1,SEH1L,SELPLG,SEPT6,SERINC5,SET,SIVA1,SLC1A5,SLC25A4,SMAD3,SPEN,SSB,STAT1,STAT3,SUPT6H,SYNCRIP,TAF1,TAF4,TAF5,TANK,TAP1,TBKBP1,THOC2,THOC7,TMEM250,TNPO1,TOP1,TP73,TPR,TRAM1,TSC2,TYRO3,UBA52,UBB,UBR4,UCKL1,UNG,VDAC1,VPS37A,VPS37B,WDR48,XPO1,ZC3H7B,ZMYND11	MammalFishAncestor	234.884
GO.Biological.Process	GO:0044419	interspecies.interaction.between.organisms	21	1.233868e-239	1.593787e-235	7.589463e-237	1.600623e+0	ABCE1,ABI1,ANXA2,ATG7,AZU1,BTRC,CALCOCO2,CAMLG,CBX5,CCNT1,CD4,CENPU,COPB1,CRTC1,CRTC2,CTBP2,CTDP1,CUL2,CUL4A,DAG1,DDX3X,DDX6,DENR,DERL1,DHX58,DHX9,DPP4,DYNC1I2,EIF2AK4,EIF3G,EIF4G1,EIF4G3,ELANE,EP300,ERCC2,EXOC1,FKBP8,FN1,GAPDH,GAS6,GBF1,GFI1,GPX1,GTF2A2,GTF2B,GYPA,HMGA1,HNRNPA1,HTATIP2,HTATSF1,HYAL2,ICAM1,IDE,IFIH1,ITGB6,IVNS1ABP,KAT2A,KDM4A,KDR,KIN,KLC1,KPNA2,KPNA4,KRT18,KRT8,LAMP1,LAMTOR5,LDLR,LEF1,LMBRD1,MAGI3,MCTS1,MDFIC,MET,MORC3,MSH6,MVB12B,NEDD4,NFKBIA,NUP133,NUP188,NUP210,NUP214,NUP93,PCSK5,PDGFRA,PDZD8,PI4KA,PLCG1,POLA1,POLR2E,PPIA,PPID,PSIP1,PSMA7,PSMB2,PSMB7,PSMB8,PSMB9,PTBP1,RAB11FIP4,RAB1B,RAB9A,RAN,RANBP1,RANBP2,RBM15,RBX1,RHOA,RNF216,RPL10,RPL19,RPL21,RPL22,RPL27A,RPL30,RPL32,RPL35,RPL39,RPL4,RPL41,RPL5,RPL9,RPLP1,RPS10,RPS15,RPS2,RPS26,RPS3A,SATB1,SEH1L,SELPLG,SEPT6,SERINC5,SET,SIVA1,SLC1A5,SLC25A4,SMAD3,SMARCA4,SMC3,SPEN,SSB,STAT1,STAT3,SUPT6H,SYNCRIP,TAF1,TAF11,TAF4,TAF5,TANK,TAP1,TARDBP,TBKBP1,TFAP4,THOC2,THOC7,TMEM250,TNPO1,TOP1,TP73,TPR,TRAM1,TSC2,TUSC2,TYRO3,UBA52,UBB,UBR4,UCKL1,ULK1,UNG,VDAC1,VPS37A,VPS37B,WDR48,XPO1,ZC3H7B,ZMYND11	MammalFishAncestor	234.798
GO.Biological.Process	GO:0009156	ribonucleoside.monophosphate.biosynthetic.process	22	5.226284e-238	6.750791e-234	3.068541e-235	3.301561e+0	ADK,ADSS,ADSSL1,AK5,AK9,AMPD2,AMPD3,APRT,ATIC,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP5S,ATP6V0A1,ATP6V0A2,IMPDH2,LHPP,PAICS,PPAT,PRPS2,RFK,SLC25A13,STOML2,UCKL1,UMPS,UPP2	MammalFishAncestor	233.171
GO.Biological.Process	GO:0048568	embryonic.organ.development	23	2.316329e-236	2.992002e-232	1.300871e-233	1.553078e+0	ACVR1,ADM,AKT1,ALDH1A2,ALDH1A3,ALX3,ARID1A,ARNT,AXIN1,BBS5,BIRC6,BPTF,CC2D2A,CCDC39,CDX2,CEP290,CHRNA9,COL11A1,COL2A1,CSF2,CTHRC1,DLX2,DLX5,DLX6,DNAJB6,DSCAML1,DVL2,EN2,ERCC2,EYA1,FBN1,FBN2,FGF8,FOLR1,FOXL2,FOXN4,FZD6,GATA3,GCM1,GJA5,GJB6,GLI1,GLI2,GLI3,GSC,HMX2,HMX3,HNF1B,HOXA1,HOXA11,HOXA3,HOXA5,HOXA6,HOXA7,HOXB1,HOXB2,HOXB3,HOXB4,HOXB5,HOXB6,HOXB7,HOXB8,HOXC11,HOXC4,HOXC9,HOXD10,HOXD3,HOXD4,HOXD9,HYAL1,ID2,IFT122,IL3,INSIG1,IRX5,KDM2B,KDR,KIT,KITLG,KMT2A,KRT8,LEF1,LHX1,MAP2K1,MED1,MED12,MEF2C,MEGF8,MIB1,MICAL2,MKKS,MYCN,MYF5,MYO15A,MYO3A,MYO3B,MYO7A,NAGLU,NIPBL,NODAL,NOTCH1,NPHP3,NR2F2,NR4A3,NTN1,OSR2,OTX1,PAX2,PAX6,PCSK5,PDGFRA,PDZD7,PITX2,PKD1,PKD2,PLCD1,POLE,POU4F3,PRKRA,PROX1,PTCH1,RARB,RBBP6,RBP4,RPL10,RYR2,SALL1,SETD2,SHH,SHOX2,SIX1,SIX2,SIX3,SIX4,SLC39A1,SLC44A4,SMAD3,SOX18,SP3,STK3,SYF2,TBX1,TBX2,TCAP,TCF7,TEAD1,TFAP2A,TGFB3,TPO,TSHZ1,USH1C,VASH1,WDPCP,WDR19,WDR48,WNT2,ZEB1,ZFPM2,ZIC1,ZNF568	MammalFishAncestor	231.524
GO.Biological.Process	GO:0007017	microtubule-based.process	24	6.512813e-236	8.412601e-232	3.505250e-233	1.603611e+0	ABRAXAS2,AKAP9,AP3B1,AP3B2,AP3M1,ARHGAP21,ARHGEF10,ARMC4,ATRX,ATXN7,AXIN1,BBS2,BCAS3,BCCIP,BLOC1S5,BRCA2,CABYR,CAMSAP1,CAMSAP2,CC2D2A,CCDC187,CCDC39,CCDC63,CCSAP,CEP120,CEP131,CEP135,CEP152,CEP192,CEP350,CETN3,CFAP46,CFAP74,CHD3,CLASP1,CLIP1,CLTC,CNP,CNTLN,CSNK1D,CUL9,DAG1,DCLK2,DCTN2,DNAAF4,DNAH1,DNAH10,DNAH11,DNAH12,DNAH2,DNAH5,DNAH7,DNAH8,DNAH9,DOCK7,DPCD,DRC1,DST,DYNC1H1,DYNC1I1,DYNC1I2,DYNC2H1,DYNC2LI1,ENSG00000258472,EYA1,FLNA,FOPNL,GABARAP,GAPDH,GCC2,GPSM2,HAUS1,HDGFL3,HTT,ICK,IFT122,IFT43,IFT80,IFT81,IFT88,INO80,KATNA1,KIF14,KIF17,KIF1A,KIF1B,KIF23,KIF3A,KIF3B,KIF3C,KIF5A,KIF5B,KIF5C,KIZ,KLC1,KLC2,KLC3,LRPPRC,MAATS1,MAP1A,MAP2,MAP7D1,MAP7D3,MARK4,MTCL1,MZT1,NAV1,NCOR1,NDE1,NDEL1,NEK2,NEK6,NEK7,NEURL1,NIN,NPHP3,NUMA1,OBSL1,ODF2,OFD1,PAX6,PEX14,PIBF1,PKD2,PPP2R3C,PRKCZ,PSRC1,RAB11A,RABL2B,RAN,RANBP1,RANBP2,RHOA,RHOT1,RHOT2,RNF19A,SDCCAG8,SETD2,SH3GL2,SLAIN2,SLK,SPAG1,SPAG17,SPAG5,SPC25,SPICE1,SPIRE1,SSX2IP,STMN3,TBCE,TEKT2,TNPO1,TRIM54,TRPV4,TTC21A,TTC21B,TTC30A,TTC30B,TTLL5,TTLL6,TUBA4A,TUBA4B,TUBB4B,TUBD1,TUBE1,TUBG1,TUBG2,TUBGCP4,TUBGCP5,TUBGCP6,UBB,UBE2B,USP33,VAMP4,WASHC1,WDR19,WDR34,WDR66,WEE1,WRAP73,ZMYND10,ZNF207	MammalFishAncestor	231.075
GO.Biological.Process	GO:0009792	embryo.development.ending.in.birth.or.egg.hatching	25	6.900657e-232	8.913579e-228	3.565431e-229	1.487852e+0	ABI1,ACVR1,ACVR2A,ADAM10,ADM,AKT1,ALDH1A2,ALX3,AMBRA1,ANKRD11,APOB,ARID1A,ARNT,ATM,ATP7A,AXIN1,BIRC6,BPTF,BRCA2,BTF3,CC2D2A,CCNB2,CDX2,CENPU,COL11A1,COL1A1,COL2A1,COL4A3BP,CSF2,CTHRC1,CTR9,CUL4A,DLX1,DLX2,DMRT2,DNAJB6,DSCAML1,DVL2,ECE1,EDNRA,ELL,ENDOG,EP300,ERCC2,EVX1,EYA1,FGF8,FKBP8,FOLR1,FOXB1,FOXD3,FZD6,GATA3,GATA6,GCM1,GDF7,GLI2,GLI3,GLMN,GPI,GSC,HNF1B,HORMAD1,HOXA1,HOXA11,HOXA3,HOXA5,HOXA6,HOXA7,HOXB1,HOXB2,HOXB3,HOXB4,HOXB5,HOXB6,HOXB7,HOXB8,HOXB9,HOXC11,HOXC5,HOXC6,HOXC9,HOXD1,HOXD10,HOXD3,HOXD4,HOXD9,HYAL1,IFT122,IRX5,ITPK1,KAT2A,KDM2B,KEAP1,KIAA1217,KIDINS220,KLHL12,KRT8,LEF1,LHX1,LIAS,LMO4,LMX1B,LRP2,MAP2K1,MED1,MED12,MEF2C,MEGF8,MFN2,MIB1,MYCN,MYF5,MYF6,MYO1E,NDEL1,NEK2,NF1,NIPBL,NODAL,NOLC1,NOTCH1,NR2F2,NRARP,NUP133,OSR2,PAX1,PAX2,PAX6,PCSK5,PDGFRA,PITX2,PKD1,PKD2,PLCD1,PLCG1,PLXNB2,POFUT1,PRDM14,PRKACB,PRKDC,PROX1,PTCH1,RBBP6,RBP4,RCN1,RESP18,RPGRIP1L,SALL4,SEC24C,SEC24D,SETD2,SF3B6,SFRP2,SHH,SHOX2,SIN3A,SIX1,SIX2,SIX4,SLC30A1,SLC39A1,SMAD3,SOX18,SOX6,SP3,STK3,SULF1,SULF2,SYF2,TBX1,TCAP,TCF7,TCTN1,TET1,TFAP2A,TGFB3,THOC2,TPM1,TSC1,TSC2,UBE2B,UBR3,VASH1,WDR19,WNT2,ZEB1,ZEB2,ZFPM2,ZNF568	MammalFishAncestor	227.05
GO.Biological.Process	GO:0043009	chordate.embryonic.development	26	6.626983e-222	8.560074e-218	3.292336e-219	1.478036e+0	ABI1,ACVR1,ACVR2A,ADAM10,ADM,AKT1,ALDH1A2,ALX3,AMBRA1,ANKRD11,APOB,ARID1A,ARNT,ATM,ATP7A,AXIN1,BIRC6,BPTF,BRCA2,BTF3,CC2D2A,CCNB2,CDX2,CENPU,COL11A1,COL1A1,COL2A1,COL4A3BP,CSF2,CTHRC1,CTR9,CUL4A,DLX1,DLX2,DMRT2,DNAJB6,DSCAML1,DVL2,ECE1,EDNRA,ELL,ENDOG,EP300,ERCC2,EYA1,FGF8,FKBP8,FOLR1,FOXB1,FOXD3,FZD6,GATA3,GATA6,GCM1,GDF7,GLI2,GLI3,GLMN,GPI,GSC,HNF1B,HORMAD1,HOXA1,HOXA11,HOXA3,HOXA5,HOXA6,HOXA7,HOXB1,HOXB2,HOXB3,HOXB4,HOXB5,HOXB6,HOXB7,HOXB8,HOXB9,HOXC11,HOXC5,HOXC6,HOXC9,HOXD1,HOXD10,HOXD3,HOXD4,HOXD9,HYAL1,IFT122,IRX5,ITPK1,KAT2A,KDM2B,KEAP1,KIAA1217,KIDINS220,KLHL12,KRT8,LEF1,LHX1,LIAS,LMO4,LMX1B,LRP2,MAP2K1,MED1,MED12,MEF2C,MEGF8,MFN2,MIB1,MYCN,MYF5,MYF6,MYO1E,NDEL1,NEK2,NF1,NIPBL,NODAL,NOLC1,NOTCH1,NR2F2,NRARP,NUP133,OSR2,PAX1,PAX2,PAX6,PCSK5,PDGFRA,PITX2,PKD1,PKD2,PLCD1,PLCG1,PLXNB2,POFUT1,PRDM14,PRKACB,PRKDC,PROX1,PTCH1,RBBP6,RBP4,RCN1,RESP18,RPGRIP1L,SALL4,SEC24C,SEC24D,SETD2,SF3B6,SFRP2,SHH,SHOX2,SIN3A,SIX1,SIX2,SIX4,SLC30A1,SLC39A1,SMAD3,SOX18,SOX6,SP3,STK3,SULF1,SULF2,SYF2,TBX1,TCAP,TCF7,TCTN1,TET1,TFAP2A,TGFB3,THOC2,TPM1,TSC1,TSC2,UBE2B,UBR3,VASH1,WDR19,WNT2,ZEB1,ZEB2,ZFPM2,ZNF568	MammalFishAncestor	217.068
GO.Biological.Process	GO:0021515	cell.differentiation.in.spinal.cord	27	3.103470e-221	4.008752e-217	1.484723e-218	2.569681e+0	DBX1,DLL4,DMRT3,DYNC2H1,EVX1,FOXN4,GDF7,GLI2,GLI3,GSX1,GSX2,HOXC10,HOXD10,ISL2,LHX1,LHX3,LHX4,LMO4,MNX1,NKX2-2,NKX6-1,NKX6-2,NOTCH1,PAX6,PHOX2A,PTCH1,SHH,TCTN1	MammalFishAncestor	216.397
GO.Biological.Process	GO:0043401	steroid.hormone.mediated.signaling.pathway	28	9.819615e-221	1.268400e-216	4.529999e-218	2.066295e+0	ARID1A,CCNE1,ESR1,ESRRB,ESRRG,FKBP4,HNF4G,LEF1,MED1,MED12,MED13,MED14,MED16,NEDD4,NR1I2,NR2C1,NR2E1,NR2E3,NR2F1,NR2F2,NR3C2,NR4A2,NR4A3,NR5A1,NR5A2,NR6A1,PAQR5,PAQR9,PIAS1,PLPP1,POU4F2,PPARG,RAN,RARB,RHOXF1,RORA,RXRB,TAF7,THRAP3,UBR5,WBP2	MammalFishAncestor	215.897
GO.Biological.Process	GO:0001708	cell.fate.specification	29	4.873573e-216	6.295194e-212	2.170757e-213	2.130087e+0	DBX1,DMRT3,EVX1,EYA1,FKBP8,FOXA2,GLI2,GLI3,GSC,GSX2,HNF1B,HOXA11,HOXC10,HOXD10,ISL2,LHX3,MNX1,MYL2,MYT1L,NKX2-2,NKX6-1,NKX6-2,NODAL,NOTCH1,PAX2,PAX6,POU3F2,POU4F1,PPDPF,PRDM14,PTCH1,SHH,SIX1,SIX2,SOX18,SOX2,SOX6,TBX1,TENM4	MammalFishAncestor	211.201
GO.Biological.Process	GO:0051223	regulation.of.protein.transport	30	1.116551e-211	1.442249e-207	4.807496e-209	1.445941e+0	ABCC8,ACSL3,ACTL6A,ACVR1C,ADCY5,ADRA2A,ANK3,ARG2,ARIH2,BAG3,BAMBI,BAP1,BCAP31,BCAS3,BMP6,BMP8A,C5AR2,CACNA1A,CACNA1C,CACNA1D,CCDC22,CD40LG,CEP131,CEP290,CFTR,CLOCK,CRH,CTSK,CYLD,DACT3,DHX36,DHX9,DPH6,DPP4,DRD3,EDAR,EDEM1,EFCAB7,EMD,ENSA,ENY2,ERLEC1,EXOC1,F2R,F2RL1,FFAR4,FGA,FGB,FGG,FKBP1B,FLNA,FN1,FOXA2,FOXP1,FYN,G6PC2,GAPDH,GAPVD1,GAS6,GATA3,GBP1,GCC2,GCG,GJA5,GLI3,GLMN,GLP1R,GLS2,GOLPH3L,GPI,GPR26,GPR27,GSK3B,HADH,HCAR2,HK1,HMGCR,HUWE1,HYAL2,ICE1,IFIH1,IRS2,ITGB1BP1,ITPR1,ITPR2,ITPR3,JUP,KANK1,KAT2A,KCNJ11,KEAP1,KIF5B,LLGL1,LLGL2,LRP1,LRRC46,MAPK11,MAPKBP1,MBP,MDFIC,MED1,MFF,MICALL2,MIDN,MIEF2,MTCL1,MTNR1B,MTOR,MXI1,MYBPC1,MYO18A,MYOM1,NBPF3,NDEL1,NF1,NFKBIA,NFKBIE,NKAP,NKX6-1,NLGN2,NOD2,NODAL,NOV,NRXN1,NUP93,OSCP1,PAK1,PDCD5,PDE8B,PDX1,PFKM,PIK3R2,PIM3,PKD1,PKD2,PLAGL2,POSTN,PPIA,PPID,PPM1A,PPM1B,PPP3CB,PRKCA,PRKCD,PRKCZ,PSMB7,PTGS2,PTPN14,PTPN23,RAB11A,RAB11FIP3,RAB23,RANGAP1,RAP1A,RAPGEF4,RBP4,RGCC,RHBDF2,RHOA,SAE1,SCFD1,SEC24A,SFN,SFRP2,SHH,SLC17A9,SLC25A4,SLC2A2,SMAD3,SNAP25,SNX3,SPHK1,SPTBN1,SREBF1,SRGN,SRI,STARD7,STXBP5,SULF2,TARDBP,TCF7L2,TENM1,TGFB3,TLR7,TLR8,TM9SF4,TMEM30A,TMSB4X,TPR,TRPV4,UBL4B,UBR5,UNC13B,UQCC2,XPO1,XPO4,ZBTB17,ZIC1	MammalFishAncestor	206.841
GO.Biological.Process	GO:0021516	dorsal.spinal.cord.development	31	1.213620e-211	1.567633e-207	5.056880e-209	4.095528e+0	DRGX,GDF7,GSX1,GSX2,HOXB8,LHX1,LHX3,LMO4,PBX3,PROX1,RFX4,UNCX	MammalFishAncestor	206.805
GO.Biological.Process	GO:0006915	apoptotic.process	32	3.870096e-209	4.999003e-205	1.562188e-206	1.409824e+0	ACTC1,ACVR1C,ADAMTSL4,AIMP1,AIMP2,AKT1,AKTIP,APOPT1,APPL1,AREL1,ARHGEF6,ATF2,ATM,ATN1,AVEN,AXIN1,BAG3,BBC3,BCAP31,BCL2L10,BIRC6,BIRC7,BMF,BNIP2,BOK,BRCA2,BRMS1,BUB1B,C5AR1,CAPN3,CASP7,CASP8AP2,CCAR1,CDCA7,CDK11A,CDK11B,CDK19,CDK5RAP3,CHAC1,CIT,CLPTM1L,CLSPN,COMP,CRH,CSE1L,CSRNP1,CSRNP2,CSRNP3,CUL2,CUL4A,DAPK2,DAPL1,DDIT3,DDX3X,DHCR24,DIABLO,DICER1,DNAJA3,DNASE1,DNASE1L3,DNASE2B,DNMT3A,DOCK1,EBAG9,EDAR,EGLN3,EIF5A,ENDOG,ENSG00000256500,EP300,ERBB3,ERCC2,ERCC6,FAIM,FAP,FASLG,FGF8,FKBP8,FNIP2,FOXL2,FOXO3,FXR1,G2E3,GABARAP,GAPDH,GAS6,GCLC,GCLM,GJB6,GLI3,GNB1,GPX1,GSK3B,HCAR2,HIP1R,HIPK3,HTATIP2,HTT,ING4,INHBA,ITGB3BP,ITPR1,JMY,KANK2,KIF1B,KITLG,KLF11,KMT2A,KRT18,KRT8,LALBA,LAMP1,LEF1,MADD,MAGI3,MCL1,MECOM,MEF2C,MFF,MFN2,MOAP1,MRPL41,MSH6,MT3,MTOR,MYBBP1A,MYD88,NDUFA13,NDUFS1,NEK6,NF1,NFKBIA,NISCH,NOTCH1,NTN1,OGT,OXR1,P2RX1,PAK1,PAK5,PAK6,PAX3,PCSK9,PDCD4,PDCD5,PDK1,PDK2,PEG10,PHLDA1,PHLDA3,PIM3,PKN2,PLAGL2,PLSCR3,POU4F1,POU4F2,POU4F3,PPID,PPP1R13B,PPP2CA,PRF1,PRKCA,PRKCB,PRKCD,PRKCQ,PRKDC,PRUNE2,PTPN6,PTRH2,RAF1,RBM5,RFK,RHOB,RHOT1,RHOT2,RNF152,RNF216,RNF34,RNF41,ROCK1,RPS27L,RPS6KB1,RRAGC,RTL10,RTN4,RYBP,RYR2,SATB1,SAV1,SCN2A,SENP1,SFN,SFRP2,SH3RF1,SHC4,SHH,SHISA5,SIVA1,SIX1,SIX3,SLC25A4,SLC5A11,SLC5A8,SLK,SLTM,SMAD3,SMNDC1,SORT1,SRGN,STAT1,STK11,STK24,STK25,STK3,SUDS3,SULF1,TAOK1,TAX1BP1,TBX1,TCHP,TFDP1,TIAF1,TIAL1,TMEM102,TNFAIP8,TNFRSF11A,TNFRSF6B,TNFSF12,TOX3,TP73,TRAF3IP2,TSC2,UBE2K,UBE2Z,UBE4B,USP53,VDAC1,VIL1,ZNF385C,ZNF443	MammalFishAncestor	204.301
GO.Biological.Process	GO:0045185	maintenance.of.protein.location	33	1.728073e-208	2.232152e-204	6.764097e-206	2.774708e+0	AKT1,ANK3,CCDC22,CD4,DAG1,DZIP1,FBN1,FBN2,FLNA,FLNB,HK1,JUP,KEAP1,LTBP1,MORC3,MXI1,NFKBIA,NFKBIE,NR5A1,PDIA2,PKD1,PKD2,SHANK1,SKP1,SPAG4,SPTBN4,SRGN,SRI,SYNE1,SYNE3,TAF3,TLN2,TMSB4X	MammalFishAncestor	203.651
GO.Biological.Process	GO:0021521	ventral.spinal.cord.interneuron.specification	34	3.573074e-201	4.615340e-197	1.357453e-198	4.302210e+0	DBX1,DMRT3,EVX1,GLI2,GLI3,LHX3,NKX6-1,NKX6-2,PAX6	MammalFishAncestor	196.336
GO.Biological.Process	GO:0070201	regulation.of.establishment.of.protein.localization	35	3.807940e-200	4.918716e-196	1.405347e-197	1.419161e+0	ABCC8,ACSL3,ACTL6A,ACVR1C,ADCY5,ADRA2A,ANK3,ARG2,ARIH2,BAG3,BAMBI,BAP1,BCAP31,BCAS3,BMF,BMP6,BMP8A,C5AR2,CACNA1A,CACNA1C,CACNA1D,CCDC22,CCT4,CD40LG,CEP131,CEP290,CFTR,CLOCK,CRH,CTSK,CYLD,DACT3,DHX36,DHX9,DPH6,DPP4,DRD3,EDAR,EDEM1,EFCAB7,EMD,ENSA,ENY2,ERLEC1,EXOC1,F2R,F2RL1,FFAR4,FGA,FGB,FGG,FKBP1B,FLNA,FN1,FOXA2,FOXP1,FYN,G6PC2,GAPDH,GAPVD1,GAS6,GATA3,GBP1,GCC2,GCG,GJA5,GLI3,GLMN,GLP1R,GLS2,GOLPH3L,GPI,GPR26,GPR27,GSK3B,HADH,HCAR2,HK1,HMGCR,HUWE1,HYAL2,ICE1,IFIH1,IRS2,ITGB1BP1,ITPR1,ITPR2,ITPR3,JUP,KANK1,KAT2A,KCNJ11,KEAP1,KIF5B,LLGL1,LLGL2,LRP1,LRRC46,MAPK11,MAPK8,MAPKBP1,MBP,MDFIC,MED1,MFF,MICALL2,MIDN,MIEF2,MTCL1,MTNR1B,MTOR,MXI1,MYBPC1,MYO18A,MYOM1,NBPF3,NDEL1,NF1,NFKBIA,NFKBIE,NKAP,NKX6-1,NLGN2,NOD2,NODAL,NOV,NRXN1,NUP93,OSCP1,PAK1,PDCD5,PDE8B,PDX1,PFKM,PIK3R2,PIM3,PKD1,PKD2,PLAGL2,POSTN,PPIA,PPID,PPM1A,PPM1B,PPP1R13B,PPP3CB,PRKCA,PRKCD,PRKCZ,PSMB7,PTGS2,PTPN14,PTPN23,RAB11A,RAB11FIP3,RAB23,RANGAP1,RAP1A,RAPGEF4,RBP4,RGCC,RHBDF2,RHOA,SAE1,SCFD1,SEC24A,SFN,SFRP2,SHH,SLC17A9,SLC25A4,SLC2A2,SMAD3,SNAP25,SNX3,SPHK1,SPTBN1,SREBF1,SRGN,SRI,STARD7,STXBP5,SULF2,TARDBP,TCF7L2,TENM1,TFDP1,TGFB3,TLR7,TLR8,TM9SF4,TMEM30A,TMSB4X,TP73,TPR,TRPV4,UBL4B,UBR5,UNC13B,UQCC2,XPO1,XPO4,YWHAQ,YWHAZ,ZBTB17,ZIC1	MammalFishAncestor	195.308
GO.Biological.Process	GO:0021510	spinal.cord.development	36	6.393309e-200	8.258237e-196	2.293955e-197	2.034000e+0	ACTL6A,AKT1,BAG3,DBX1,DLL4,DMRT3,DRGX,DYNC2H1,ERCC2,EVX1,FOXB1,FOXN4,GDF7,GLI2,GLI3,GSX1,GSX2,HOXB8,HOXC10,HOXD10,IFT122,ISL2,LHX1,LHX3,LHX4,LMO4,MED12,MNX1,MTOR,NEUROG3,NF1,NKX2-2,NKX6-1,NKX6-2,NOTCH1,PAX6,PBX3,PHOX2A,PKD1,PKD2,PROX1,PTCH1,PTPRS,RELN,RFX4,SHH,TCTN1,UNCX,VLDLR,ZIC1	MammalFishAncestor	195.083
GO.Biological.Process	GO:0009755	hormone-mediated.signaling.pathway	37	2.527113e-197	3.264272e-193	8.822356e-195	1.914719e+0	ACSL1,ADIPOR2,ARID1A,CCNE1,CRH,ESR1,ESRRB,ESRRG,FKBP4,FSHR,HNF4G,LATS2,LEF1,LHCGR,MED1,MED12,MED13,MED14,MED16,NEDD4,NR1I2,NR2C1,NR2E1,NR2E3,NR2F1,NR2F2,NR3C2,NR4A2,NR4A3,NR5A1,NR5A2,NR6A1,PAQR5,PAQR9,PIAS1,PLPP1,POU4F2,PPARG,RAN,RARB,RHOXF1,RORA,RXRB,TAF7,THRAP3,UBR5,WBP2	MammalFishAncestor	192.486
GO.Biological.Process	GO:0036035	osteoclast.development	38	2.283865e-196	2.950068e-192	7.763338e-194	6.819371e+0	ANXA2,FOXP1,LRRK1	MammalFishAncestor	191.53
GO.Biological.Process	GO:0021517	ventral.spinal.cord.development	39	2.805134e-196	3.623392e-192	9.290748e-194	2.445204e+0	DBX1,DLL4,DMRT3,DYNC2H1,EVX1,FOXN4,GLI2,GLI3,HOXC10,HOXD10,ISL2,LHX1,LHX3,LHX4,LMO4,MNX1,NKX2-2,NKX6-1,NKX6-2,PAX6,PHOX2A,PTCH1,RELN,SHH,TCTN1,VLDLR	MammalFishAncestor	191.441
GO.Biological.Process	GO:0016197	endosomal.transport	40	7.449355e-195	9.622332e-191	2.405583e-192	1.911784e+0	ABCA1,AKTIP,ANKFY1,ANKRD50,AP1G1,AP5M1,AP5Z1,ARFRP1,ARL1,BLOC1S5,CDX2,CLN5,CLTC,CORO7,DCLK1,DENND1B,DENND5A,DOPEY1,DOPEY2,ERC1,EVI5,FAM109A,GBF1,GCC2,LYST,MICALL2,MON2,MVB12B,PCDHGA3,PIK3R4,PIKFYVE,PTPN23,RAB10,RAB11A,RAB11FIP3,RAB12,RAB32,RAB35,RAB5C,RAB9A,RHOB,RILP,SDCCAG3,SNF8,SNX2,SNX31,SNX33,SORT1,SPAG9,STAM2,STX10,STX8,TBC1D14,TBC1D5,TMEM87A,UBA52,UBB,UBE2O,VPS13A,VPS13C,VPS26A,VPS29,VPS33A,VPS37A,VPS37B,VPS39,VPS41,VPS54,VTI1A,VTI1B,WASHC1,WDR81,ZFYVE21	MammalFishAncestor	190.017
GO.Biological.Process	GO:0042593	glucose.homeostasis	41	3.014372e-194	3.893664e-190	9.496742e-192	2.003141e+0	ABCC8,ADIPOR2,ADRA2A,AKT1,BHLHA15,CRTC2,ENDOG,ERO1B,FOXO3,G6PC2,GAS6,GCLC,GCLM,GJB6,GPI,GPR21,HECTD4,HK1,HKDC1,ICAM1,IRS2,KCNJ11,LEPR,MBD5,MEN1,MTNR1B,OGT,PAX2,PAX6,PDK2,PDK3,PDK4,PDX1,PFKM,PIK3R2,PLSCR3,POLG,POMC,PPARG,PTCH1,PTPN2,PTPRN,PTPRN2,PYGL,RAB11FIP2,RAF1,RANBP2,RAP1A,RBP4,SERPINF1,SIN3A,SLC2A4,STAT3,STK11,TCF7L2,TRPV4,TWNK,UNC13B,ZNF236	MammalFishAncestor	189.41
GO.Biological.Process	GO:0035295	tube.development	42	1.039698e-192	1.342978e-188	3.197566e-190	1.408407e+0	ACAT1,ACVR1,ADAMTS16,ADM,AIMP2,ALDH1A2,AMBRA1,ARG2,ARID1A,ASXL1,ATP7A,ATRX,BBS5,BCAS3,BRIP1,BTRC,CC2D2A,CCDC39,CDX2,CLIC4,COL4A1,CRH,CRLF1,CTHRC1,CTNNBIP1,DAG1,DLG5,DLL4,DVL2,EDAR,EDNRA,EDNRB,EP300,EPHA4,ESR1,EYA1,FAT4,FGF8,FKBP8,FOLR1,FOXB1,FOXD1,FOXN4,FOXP2,FZD6,GATA3,GATA6,GDF7,GJA5,GLI1,GLI2,GLI3,GLMN,GPSM2,GSC,HHIP,HNF1B,HOXA1,HOXA11,HOXA5,HOXD11,HOXD13,ID2,IFT122,IRX1,IRX2,IRX3,ITGA6,ITGB1BP1,ITGB4,ITPK1,JAG1,KAT2A,KDM2B,KDM5B,KIT,KLF5,LEF1,LHX1,LHX3,LIAS,LMO4,LRP2,MAN1A2,MAP2K1,MED1,MED12,MEF2C,MEGF8,MET,MIB1,MICAL2,MKKS,MYCN,NF1,NIPBL,NKX2-1,NKX2-2,NKX2-8,NODAL,NOTCH1,NPHP3,NPNT,NR4A3,NRARP,NTN1,NUMA1,NUP133,PAK1,PAX2,PAX6,PCSK5,PDGFRA,PDX1,PGF,PHB2,PITX2,PKD1,PKD2,PLXNB2,PLXND1,POU3F3,PRKACB,PRKD2,PROX1,PTCH1,PTK6,RAB3A,RARB,RBM15,RBP4,RHOA,RHOB,RIDA,RPGRIP1L,RYR2,SALL1,SALL4,SAV1,SDC1,SDCCAG8,SETD2,SFRP2,SHH,SHOX2,SIM1,SIX1,SIX2,SMAD1,SMAD3,SMAD6,SMAD9,SOX18,SP3,SPARC,SPDEF,SREBF1,STARD13,STAT1,STK3,STK40,TBX1,TBX2,TBX4,TCF7,TCTN1,TGFB3,TSC1,TSC2,WDR19,WDR48,WNT2,WNT7A,WT1,ZEB1,ZEB2,ZFPM2	MammalFishAncestor	187.872
GO.Biological.Process	GO:0009123	nucleoside.monophosphate.metabolic.process	43	2.760271e-192	3.565442e-188	8.291726e-190	1.977860e+0	ADK,ADSS,ADSSL1,AFG1L,AK4,AK5,AK9,ALDOC,AMPD2,AMPD3,APRT,ATIC,ATP1A2,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP5S,ATP6V0A1,ATP6V0A2,ATP6V1A,COX6C,COX7B,COX8C,DCTD,DLD,DLG4,DNPH1,DTYMK,DUT,ENO1,ENO2,ENO4,ENSG00000266953,ENTPD8,GALK1,GAPDH,GPI,HK1,HKDC1,IMPDH2,LHPP,MAGI3,MYH3,MYH4,MYH8,NADK,NDUFA1,NDUFA12,NDUFA13,NDUFA5,NDUFAF7,NDUFB10,NDUFB5,NDUFS1,NDUFS6,NDUFS7,NDUFV2,NMNAT1,NT5C2,NT5E,NUDT3,OGDH,OLA1,PAICS,PFKM,PGAM4,PGK1,PGM1,PPAT,PRPS2,RFK,SLC25A13,STOML2,TAZ,TPI1,UCKL1,UMPS,UPP2,UQCRHL,UQCRQ	MammalFishAncestor	187.448
GO.Biological.Process	GO:0000226	microtubule.cytoskeleton.organization	44	9.234121e-192	1.192771e-187	2.710844e-189	1.672642e+0	ABRAXAS2,AKAP9,ARHGEF10,ARMC4,ATRX,ATXN7,AXIN1,BBS2,BCAS3,BCCIP,BRCA2,CAMSAP1,CAMSAP2,CC2D2A,CCDC187,CCDC39,CCDC63,CCSAP,CEP120,CEP135,CEP152,CEP192,CEP350,CETN3,CFAP46,CFAP74,CHD3,CLASP1,CLIP1,CNP,CNTLN,CSNK1D,CUL9,DAG1,DCLK2,DCTN2,DNAAF4,DNAH1,DNAH5,DNAH7,DNAH8,DOCK7,DRC1,DYNC1H1,ENSG00000258472,EYA1,FLNA,FOPNL,GABARAP,GAPDH,GCC2,GPSM2,HAUS1,HDGFL3,HTT,INO80,KIF23,KIF3A,KIF3B,KIZ,MAP1A,MAP2,MAP7D1,MAP7D3,MARK4,MTCL1,MZT1,NAV1,NCOR1,NDE1,NDEL1,NEK2,NEK6,NEK7,NEURL1,NIN,NUMA1,OBSL1,ODF2,PAX6,PEX14,PIBF1,PKD2,PPP2R3C,PRKCZ,PSRC1,RAB11A,RAN,RANBP1,RANBP2,RHOA,RNF19A,SDCCAG8,SETD2,SLAIN2,SLK,SPAG1,SPAG17,SPAG5,SPC25,SPICE1,SPIRE1,SSX2IP,STMN3,TBCE,TEKT2,TRPV4,TTLL5,TTLL6,TUBE1,TUBG1,TUBG2,TUBGCP4,TUBGCP5,TUBGCP6,UBE2B,USP33,VAMP4,WASHC1,WEE1,WRAP73,ZMYND10,ZNF207	MammalFishAncestor	186.923
GO.Biological.Process	GO:0007507	heart.development	45	7.074097e-190	9.137611e-186	2.030580e-187	1.444799e+0	ACTC1,ACVR1,ADAMTS9,ADIPOR2,ADM,ALDH1A2,ANK2,ARID1A,ARMC4,ASXL1,ATF2,ATM,BBS5,BORCS8,C5orf42,CACNA1C,CC2D2A,CCDC39,CDKL1,COL11A1,COL2A1,COL4A3BP,CPE,CRKL,DAW1,DHRS3,DLL4,DNAH11,DNAH5,DRC1,DVL2,DYNC2H1,ECE1,EDNRA,EP300,ERBB3,EYA1,FAT4,FBN1,FGF8,FOLR1,FOXN4,FREM2,GALNT11,GATA3,GATA6,GJA5,GLI2,GLI3,IFT122,IRX4,JAG1,KAT2A,KCNJ8,KDM6B,LMO4,LRP2,LTBP1,MAP2K1,MAP2K5,MED1,MED12,MEF2C,MEGF8,MIB1,MICAL2,MKKS,MMP21,MNAT1,MTOR,MYBPC3,MYH11,MYL2,NDUFV2,NEDD4,NEXN,NF1,NIPBL,NODAL,NOTCH1,NPHP3,NPPA,NPPB,NRP2,OBSL1,PARVA,PCSK5,PDCD4,PDGFRA,PITX2,PKD1,PKD2,PLCE1,PLXND1,POFUT1,POU4F1,POU6F1,PPARG,PPP3CB,PRKDC,PROX1,PROX2,PTCH1,RAF1,RARB,RB1CC1,RBM15,RBM20,RBP4,RPGRIP1L,RTN4,RYR1,RYR2,SALL1,SALL4,SAV1,SCN5A,SETD2,SFRP2,SGCG,SHH,SHOX2,SIX1,SMAD1,SMAD3,SMAD6,SMARCD3,SMYD2,SOX18,SOX6,SPARC,SRI,STK3,TAB2,TAZ,TBX1,TBX2,TCAP,TENM4,TGFBR3,TNNC1,TNNI1,TNNT2,TPM1,TSC1,TSC2,UBE4B,WNT2,WT1,XIRP2,ZFPM2	MammalFishAncestor	185.039
GO.Biological.Process	GO:1903845	negative.regulation.of.cellular.response.to.transforming.growth.factor.beta.stimulus	46	8.597822e-190	1.110581e-185	2.414306e-187	2.655711e+0	ADAM17,BAMBI,BCL9L,DLX1,FBN1,FBN2,LDLRAD4,LTBP1,NKX2-1,ONECUT1,ONECUT2,PEG10,PPM1A,PRDM16,SKOR1,SMAD3,SMAD6,SNX25,TGFB3,TGFBR3,UBA52,UBB,VASN,WFIKKN2,ZNF451	MammalFishAncestor	184.954
GO.Biological.Process	GO:0043576	regulation.of.respiratory.gaseous.exchange	47	1.296674e-189	1.674914e-185	3.563646e-187	3.657572e+0	ATP1A2,FTO,GLRA1,GLS,GSX2,MTG2,NLGN2,NLGN3,NR4A2,PBX3,PHOX2A,PHOX2B,TSHZ3	MammalFishAncestor	184.776
GO.Biological.Process	GO:0072359	circulatory.system.development	48	6.203988e-189	8.013691e-185	1.669519e-186	1.339075e+0	ACTC1,ACVR1,ADAMTS9,ADIPOR2,ADM,AIMP1,AKT1,ALDH1A2,ANGPTL3,ANGPTL6,ANK2,ANXA2,APOB,ARHGAP22,ARHGAP24,ARID1A,ARMC4,ASXL1,ATF2,ATM,ATP5B,ATP7A,BBS5,BCAS3,BORCS8,C5orf42,CACNA1C,CC2D2A,CCDC39,CDKL1,CDX2,CLIC4,COL11A1,COL1A1,COL1A2,COL2A1,COL4A1,COL4A2,COL4A3BP,CPE,CRKL,CSPG4,DAG1,DAW1,DDIT3,DHRS3,DLL4,DNAH11,DNAH5,DRC1,DVL2,DYNC2H1,ECE1,ECM1,EDNRA,ELK3,ENPEP,EP300,ERBB3,EYA1,FAP,FAT4,FBN1,FGF8,FLT1,FN1,FOLR1,FOXN4,FREM2,FZD8,GALNT11,GATA3,GATA6,GJA5,GLI2,GLI3,GLMN,GPI,GPX1,HOXA1,HOXA3,HOXA7,HOXB13,HOXB3,HPSE,HSPG2,HTATIP2,IFT122,IMMP2L,IRX4,ITGB1BP1,JAG1,KAT2A,KCNJ8,KDM6B,KDR,KLF5,LEF1,LEPR,LMO4,LRP1,LRP2,LTBP1,MAP2K1,MAP2K5,MED1,MED12,MEF2C,MEGF8,MEIS1,MIB1,MICAL2,MKKS,MMP2,MMP21,MNAT1,MTOR,MYBPC3,MYH11,MYL2,MYO1E,NDUFS6,NDUFV2,NEDD4,NEXN,NF1,NIPBL,NODAL,NOTCH1,NOV,NOX1,NPHP3,NPPA,NPPB,NR2F2,NRARP,NRCAM,NRP2,OBSL1,OTULIN,PARVA,PAX6,PCSK5,PDCD4,PDE3B,PDGFRA,PGF,PIK3CB,PIK3R6,PITX2,PKD1,PKD2,PLCD1,PLCE1,PLXND1,POFUT1,POU4F1,POU6F1,PPARG,PPP3CB,PRKCA,PRKD2,PRKDC,PROK1,PROK2,PROX1,PROX2,PTCH1,PTGS2,PTPN14,RAF1,RAPGEF2,RARB,RASA1,RB1CC1,RBM15,RBM20,RBP4,RHOB,RNF213,RORA,RPGRIP1L,RTN4,RYR1,RYR2,SALL1,SALL4,SAV1,SCN5A,SERPINF2,SETD2,SFRP2,SGCG,SHH,SHOX2,SIX1,SMAD1,SMAD3,SMAD6,SMARCD3,SMYD2,SOX18,SOX6,SPARC,SPHK1,SRI,STK11,STK3,TAB2,TAZ,TBX1,TBX2,TBX4,TCAP,TCF7L2,TENM4,TGFBR3,TNFSF12,TNNC1,TNNI1,TNNT2,TPM1,TSC1,TSC2,UBE4B,VASH1,WDPCP,WNT2,WNT7A,WT1,XIRP2,ZFPM2,ZNF304	MammalFishAncestor	184.096
GO.Biological.Process	GO:0060579	ventral.spinal.cord.interneuron.fate.commitment	49	7.914893e-188	1.022367e-183	2.086463e-185	3.841437e+0	DBX1,DLL4,DMRT3,EVX1,FOXN4,GLI2,GLI3,LHX3,NKX2-2,NKX6-1,NKX6-2,PAX6	MammalFishAncestor	182.99
GO.Biological.Process	GO:0030522	intracellular.receptor.signaling.pathway	50	4.509046e-187	5.824335e-183	1.164867e-184	1.868867e+0	ALDH1A2,ARID1A,ARNT,CCNE1,CREM,CYLD,ESR1,ESRRB,ESRRG,FKBP4,HNF4G,IFIH1,LSM14A,MED1,MED12,MED13,MED14,MED16,NCOA2,NEDD4,NFKBIA,NOD2,NR1I2,NR2E3,NR2F1,NR2F2,NR4A2,NR4A3,NR5A1,NR5A2,NR6A1,OTULIN,PDK3,PIAS1,PLPP1,POU4F2,PPARG,RAN,RARB,RHOXF1,RNF34,RORA,RXRB,SREBF1,STAT3,TAB2,TAF7,TBX1,THRAP3,UBA52,UBB,UBR5,WBP2	MammalFishAncestor	182.235
GO.Biological.Process	GO:0021534	cell.proliferation.in.hindbrain	51	6.354219e-187	8.207745e-183	1.609362e-184	5.197958e+0	C5AR1,RERE,RORA,SHH	MammalFishAncestor	182.086
GO.Biological.Process	GO:0031581	hemidesmosome.assembly	52	1.680862e-185	2.171169e-181	4.175326e-183	7.832891e+0	COL17A1,ITGA6,ITGB4,LAMA3,LAMC1,LAMC2,PLEC	MammalFishAncestor	180.663
GO.Biological.Process	GO:0051235	maintenance.of.location	53	1.730822e-185	2.235703e-181	4.218307e-183	2.242334e+0	ACVR1C,AKAP9,AKT1,ANGPTL3,ANK3,ARHGAP21,CCDC22,CD4,DAG1,DZIP1,FBN1,FBN2,FLNA,FLNB,GPSM2,HEXB,HK1,JUP,KEAP1,LDAH,LTBP1,MORC3,MXI1,NFKBIA,NFKBIE,NR5A1,PDIA2,PKD1,PKD2,POLR2M,SHANK1,SKP1,SLC18A2,SPAG4,SPTBN4,SRGN,SRI,STAT5B,SYNE1,SYNE3,TAF3,TLN2,TMSB4X	MammalFishAncestor	180.651
GO.Biological.Process	GO:0010499	proteasomal.ubiquitin-independent.protein.catabolic.process	54	1.979479e-185	2.556893e-181	4.734987e-183	9.517715e+0	ENC1,KEAP1,NFE2L2	MammalFishAncestor	180.592
GO.Biological.Process	GO:0061515	myeloid.cell.development	55	4.292631e-185	5.544791e-181	1.008144e-182	3.009174e+0	ABI1,ANXA2,EP300,ERCC2,EVI2B,FOXP1,KIT,LRRK1,MED1,MEIS1,PTPN6,SLC11A2,SOX6	MammalFishAncestor	180.256
GO.Biological.Process	GO:0030512	negative.regulation.of.transforming.growth.factor.beta.receptor.signaling.pathway	56	5.201762e-185	6.719116e-181	1.199842e-182	2.640957e+0	ADAM17,BAMBI,BCL9L,FBN1,FBN2,LDLRAD4,LTBP1,NKX2-1,ONECUT1,ONECUT2,PEG10,PPM1A,PRDM16,SKOR1,SMAD3,SMAD6,SNX25,TGFB3,TGFBR3,UBA52,UBB,VASN,WFIKKN2,ZNF451	MammalFishAncestor	180.173
GO.Biological.Process	GO:0001654	eye.development	57	5.031020e-184	6.498569e-180	1.140100e-181	1.533109e+0	ABCB5,ACTL6A,ALDH1A2,ALDH1A3,ARID1A,AXIN1,BMP6,C12orf57,CACNA1C,CC2D2A,CEP290,CLCN2,CLIC4,COL4A1,CRB1,CRYBA1,CRYGA,CRYGB,CRYGD,FASLG,FBN1,FBN2,FKBP8,FOXL2,FOXN4,FOXP2,FSCN2,GATA3,GJA8,GLI3,GNAT1,GNAT2,GNB1,GPD2,IFT122,IMPDH2,INHBA,IRX5,JAG1,KDM2B,KDM5B,LAMB2,LHX1,LPCAT1,MAB21L1,MAB21L2,MED1,MEGF11,MEIS1,MEIS2,MFN2,MIP,MYF5,MYO7A,MYOM1,MYOM2,NAGLU,NF1,NIPBL,NKD1,NR2E1,NR2E3,OSR2,PAPD4,PAX2,PAX6,PDE6C,PDGFRA,PITX2,PITX3,POU4F2,PROX1,PROX2,RAB11FIP4,RAB18,RARB,RBP4,RCN1,RHO,RPGRIP1L,RS1,SDHAF4,SDK1,SDK2,SERPINF1,SHH,SIX3,SIX6,SLC39A5,SMAD3,SMARCA4,SMARCD3,SOX2,SP3,STAT3,TBX2,TENM3,TFAP2A,TTLL5,TUB,TWSG1,VAX1,WDPCP,WDR19,WNT2,WNT2B,WNT5B,WNT7A,WT1,XRN2,ZEB1	MammalFishAncestor	179.187
GO.Biological.Process	GO:0034284	response.to.monosaccharide	58	5.018921e-182	6.482940e-178	1.117748e-179	2.096359e+0	ACVR1C,ATG7,EIF2B2,ENDOG,ENSA,FKBP1B,FOXO3,GAS6,GCLC,GCLM,GJB6,HNF1B,ICAM1,IRS2,KCNJ11,MEN1,NKX2-2,NKX6-1,PAX2,PDK3,PDX1,POLG,PTGS2,PTPRN,PTPRN2,RAB11FIP2,RAF1,RAP1A,RPS6KB1,SELENOS,SERPINF1,SIN3A,SLC26A6,SLC2A5,SPARC,SREBF1,TCF7L2,TWNK,UNC13B,ZNF236	MammalFishAncestor	177.188
GO.Biological.Process	GO:0021930	cerebellar.granule.cell.precursor.proliferation	59	6.586946e-182	8.508358e-178	1.442095e-179	5.157976e+0	RERE,RORA,SHH	MammalFishAncestor	177.07
GO.Biological.Process	GO:0042455	ribonucleoside.biosynthetic.process	60	1.292543e-181	1.669578e-177	2.782630e-179	2.585434e+0	ACAT1,ADK,ADSS,ADSSL1,AK5,AK9,AMD1,APRT,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP5S,ATP6V0A1,ATP6V0A2,IMPDH2,NME4,NT5E,PAPSS1,PDC,PDCL2,PRPS2,PRTFDC1,SLC25A13,SLC35B2,SLC35B3,STOML2,UCKL1,UMPS,UPP2	MammalFishAncestor	176.777
GO.Biological.Process	GO:0061351	neural.precursor.cell.proliferation	61	1.916710e-180	2.475814e-176	4.058712e-178	2.212153e+0	ARX,C5AR1,CEP120,DCT,DOCK7,EMX2,FGF8,FZD6,GLI3,HHIP,KIF14,KIF1A,LEF1,NDE1,PLXNB2,POU3F2,POU3F3,RAB10,RERE,RORA,SHH,SIX3,SLC39A5,WNT2,WNT7A,ZEB2,ZNF503	MammalFishAncestor	175.606
GO.Biological.Process	GO:0009746	response.to.hexose	62	3.907181e-179	5.046906e-175	8.140170e-177	2.103398e+0	ACVR1C,ATG7,EIF2B2,ENDOG,ENSA,FKBP1B,FOXO3,GAS6,GCLC,GCLM,GJB6,HNF1B,ICAM1,IRS2,KCNJ11,MEN1,NKX2-2,NKX6-1,PAX2,PDK3,PDX1,POLG,PTGS2,PTPRN,PTPRN2,RAB11FIP2,RAF1,RAP1A,RPS6KB1,SELENOS,SERPINF1,SIN3A,SLC26A6,SLC2A5,SREBF1,TCF7L2,TWNK,UNC13B,ZNF236	MammalFishAncestor	174.297
GO.Biological.Process	GO:0071407	cellular.response.to.organic.cyclic.compound	63	1.025088e-178	1.324106e-174	2.101756e-176	1.469890e+0	AANAT,ABCA1,ABCB4,ACOD1,ADCY5,ADCY6,AGO1,AGO3,AGO4,AKAP6,AKAP9,AKT1,ALPL,AQP9,ARID1A,ATG7,ATP1A2,BTRC,CASP7,CCDC62,CCNE1,CFTR,COL1A1,CRH,DAG1,DGCR8,DHX9,DIAPH1,DICER1,ESR1,ESRRB,ESRRG,FECH,FKBP4,FLT3,FOLR1,FOLR2,FOXO3,GABRA1,GABRB2,GABRG2,GCLC,GCLM,GJB2,GLI2,GNB1,HNF4G,HNRNPD,HRH1,ICAM1,IFIH1,IMPACT,INHBA,ITGA6,ITPR2,JUP,KCNJ11,KLF5,LEF1,MED1,MED12,MED13,MED14,MED16,MEF2C,MGMT,MSR1,NEDD4,NFKBIA,NOD2,NR1I2,NR2C1,NR2E1,NR2E3,NR2F1,NR2F2,NR3C2,NR4A2,NR4A3,NR5A1,NR5A2,NR6A1,OSBPL7,P2RY11,P2RY12,P2RY13,PAQR5,PAQR9,PDE12,PIAS1,PKD2,PLA2G4F,PLPP1,POU4F1,POU4F2,PPARG,PPP1R9B,PRKRA,PTCH1,PTGS2,PUM1,PUM2,RAN,RAP1A,RAPGEF2,RARB,RECQL5,RHOXF1,RORA,RPL32,RPS6KB1,RXRB,RYR1,RYR2,RYR3,SERPINF1,SIN3A,SIX1,SLC26A6,SMAD1,SMAD3,SMAD9,SP5,SSH1,STAT3,TAF1,TAF7,TFAP4,THRAP3,TMF1,UBR5,URI1,WBP2,WT1,ZC3H7B,ZFP36L2	MammalFishAncestor	173.878
GO.Biological.Process	GO:0032870	cellular.response.to.hormone.stimulus	64	2.186894e-178	2.824811e-174	4.413767e-176	1.466196e+0	ABCB4,ACACA,ACOD1,ACSL1,ADCY5,ADCY6,ADCY7,ADCY9,ADIPOR2,ADRA2A,AGTR1,AGTRAP,AHCYL1,AKT1,APOB,APPL1,APRT,ARID1A,ATP1A2,ATP6V0A1,ATP6V0A2,ATP6V1A,ATP6V1D,ATP6V1F,ATP6V1G3,BAIAP2,BAIAP2L1,BBS2,BRIP1,CCNE1,CPEB2,CRH,CTSS,CYFIP1,EIF4EBP2,EIF5A,ENSG00000278139,ESR1,ESRRB,ESRRG,FBN1,FECH,FGB,FKBP4,FLT3,FOS,FOXO3,FSHR,FYN,GATA6,GCG,GCLC,GCLM,GJB2,GLP1R,GNB1,GNB3,GNB4,GNG4,GNG5,HNF4G,ICAM1,IDE,INHBA,IRS2,JUND,KIT,KL,LATS2,LEF1,LEPR,LHCGR,MARS,MED1,MED12,MED13,MED14,MED16,MEF2C,MEN1,MKKS,MT3,MYO5A,NCOA2,NDEL1,NEDD4,NFE2L2,NKX6-1,NOTCH1,NPFFR1,NR1I2,NR2C1,NR2E1,NR2E3,NR2F1,NR2F2,NR3C2,NR4A2,NR4A3,NR5A1,NR5A2,NR6A1,NSMF,PAK1,PAQR5,PAQR9,PCSK9,PDE3B,PDK2,PDK4,PGF,PIAS1,PIK3R2,PIK3R3,PLPP1,POU4F2,PPARG,PPAT,PRKACB,PRKAR2A,PRKCD,PRKCZ,PRKDC,PTGFR,PTPN2,RAB10,RAN,RANGAP1,RARB,RHOXF1,RORA,RPL32,RPS6KB1,RXRB,SELENOS,SERPINF1,SLC2A4,SMARCC1,SREBF1,STAT3,STAT5A,STAT5B,TAF7,TBC1D4,TFAP4,THRAP3,UBR5,URI1,WBP2,WT1,ZFP36L2,ZNF106	MammalFishAncestor	173.549
GO.Biological.Process	GO:0009161	ribonucleoside.monophosphate.metabolic.process	65	3.297946e-178	4.259957e-174	6.553780e-176	1.963086e+0	ADK,ADSS,ADSSL1,AFG1L,AK4,AK5,AK9,ALDOC,AMPD2,AMPD3,APRT,ATIC,ATP1A2,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP5S,ATP6V0A1,ATP6V0A2,ATP6V1A,COX6C,COX7B,COX8C,DLD,DLG4,ENO1,ENO2,ENO4,ENSG00000266953,GALK1,GAPDH,GPI,HK1,HKDC1,IMPDH2,LHPP,MAGI3,MYH3,MYH4,MYH8,NADK,NDUFA1,NDUFA12,NDUFA13,NDUFA5,NDUFAF7,NDUFB10,NDUFB5,NDUFS1,NDUFS6,NDUFS7,NDUFV2,NMNAT1,NT5C2,NT5E,NUDT3,OGDH,OLA1,PAICS,PFKM,PGAM4,PGK1,PGM1,PPAT,PRPS2,RFK,SLC25A13,STOML2,TAZ,TPI1,UCKL1,UMPS,UPP2,UQCRHL,UQCRQ	MammalFishAncestor	173.371
GO.Biological.Process	GO:0021522	spinal.cord.motor.neuron.differentiation	66	1.376299e-177	1.777765e-173	2.693584e-175	2.620345e+0	DYNC2H1,GLI2,GLI3,HOXC10,HOXD10,ISL2,LHX3,LHX4,LMO4,MNX1,NKX2-2,NKX6-1,NKX6-2,PAX6,PHOX2A,PTCH1,SHH,TCTN1	MammalFishAncestor	172.75
GO.Biological.Process	GO:0043547	positive.regulation.of.GTPase.activity	67	5.810814e-177	7.505828e-173	1.120273e-174	1.544910e+0	ACAP1,ADGRB3,ADPRHL1,ADRB1,AGAP5,AGFG1,AGRN,ARFGAP1,ARHGAP10,ARHGAP12,ARHGAP15,ARHGAP18,ARHGAP19,ARHGAP21,ARHGAP22,ARHGAP24,ARHGAP29,ARHGAP45,ARHGAP9,ARHGDIG,ARHGEF10,ARHGEF16,ARHGEF38,ARHGEF6,ASAP2,AXIN1,BCAS3,BNIP2,CCL20,CDC42EP4,CDKL5,CHN1,CORO1C,DENND1B,DEPDC7,DOCK1,DOCK4,DOCK7,DOCK8,DOCK9,DVL2,EVI5,F2R,F2RL1,FAM13A,FZD10,GAPVD1,GIT1,GIT2,GNAO1,GNB5,GRTP1,GSK3B,HACD3,ICAM1,IQSEC1,ITGA6,KALRN,LARS,LIMS1,LLGL1,LLGL2,MYO9A,NDEL1,NF1,NPRL2,PGAM5,PIK3R2,PKP4,PREX1,PREX2,PRTN3,RABGAP1,RALBP1,RALGAPA1,RALGAPA2,RANBP1,RANBP2,RANGAP1,RAP1A,RAP1GAP,RAPGEF2,RAPGEF6,RASA1,RASA3,RASGEF1B,RASGRP2,RASGRP3,RGS11,RGS12,RGS22,RIC8B,RIN1,RSU1,SIPA1L1,STARD13,STXBP5,TBC1D13,TBC1D14,TBC1D4,TBC1D5,TBCK,TIAM2,TSC1,TSC2	MammalFishAncestor	172.125
GO.Biological.Process	GO:0007417	central.nervous.system.development	68	8.190118e-175	1.057918e-170	1.555761e-172	1.295345e+0	ABCB4,ACAT1,ACSL3,ACTB,ACTL6A,ADAM22,ADAM23,AK4,AK8,AKT1,AKT3,ALDH1A2,ALDH1A3,ANKLE2,ANXA3,ARID1A,ARMC4,ARSB,ARX,ATIC,ATM,ATN1,ATP7A,ATRX,AXIN1,BAG3,BAIAP2,BARHL1,BBS2,BOK,BPTF,BRCA2,C12orf57,C16orf45,C5AR1,C5orf42,CDK5RAP3,CEP120,CEP290,CHD5,CHST8,CIC,CLN5,CNP,CNTNAP1,COL2A1,COL4A1,COX7B,CRH,CTTNBP2,DBX1,DCLK1,DCLK2,DCT,DLG5,DLL4,DLX1,DLX2,DLX5,DMRT3,DNAH5,DNER,DOCK7,DPCD,DRGX,DRP2,DSCAML1,DYNC2H1,EFNA2,EIF2B2,EMX2,EN2,EPHA4,ERCC2,EVX1,EZH1,FANCC,FAT4,FEZF1,FGF8,FLNA,FOXB1,FOXN4,FOXO3,FOXP2,FYN,FZD6,GCM1,GDF7,GLI1,GLI2,GLI3,GNAO1,GNB4,GNPAT,GSC,GSK3B,GSX1,GSX2,H3F3B,HAPLN4,HDAC10,HDAC11,HELT,HERC1,HMX2,HMX3,HNF1B,HNRNPD,HOXB1,HOXB2,HOXB3,HOXB8,HOXC10,HOXD10,HSPG2,HTR5A,IFT122,IMMP2L,INA,INHBA,IRS2,ISL2,KAT2A,KDM2B,KDM6B,KIF14,KIF1A,KIF5B,KNDC1,LAMB1,LAMB2,LDB1,LEF1,LHX1,LHX3,LHX4,LMO4,LRP1,LRP2,MAP2,MAP2K1,MAPKAP1,MBP,MDK,MED1,MED12,MEN1,METTL14,MKKS,MNAT1,MNX1,MT3,MTOR,NAGLU,NAV2,NCAN,NDE1,NDEL1,NEURL1,NEUROD2,NEUROG3,NF1,NIPBL,NKX2-1,NKX2-2,NKX6-1,NKX6-2,NLGN3,NODAL,NOTCH1,NR2E1,NR2F2,NR4A2,NR4A3,NRCAM,OGDH,OTP,OTX1,OTX2,PAFAH1B3,PAK1,PAPD4,PAX2,PAX6,PBX3,PDX1,PHF8,PHLPP2,PHOX2A,PHOX2B,PITX1,PITX2,PITX3,PKD1,PKD2,PLXNB2,POU3F1,POU3F2,POU3F3,POU4F1,POU6F1,POU6F2,PRDM8,PRKDC,PROX1,PTCH1,PTPRG,PTPRS,PTPRZ1,QARS,RAB18,RAPGEF2,RARB,RELN,RERE,RFX4,RHOA,RIDA,ROR1,RORA,RPGRIP1L,RTN4,RTN4RL1,SALL1,SALL3,SCN5A,SEC16A,SEMA3F,SEMA6D,SETD2,SEZ6,SH3GL2,SHH,SIX1,SIX3,SLC38A3,SLC4A10,SLC6A11,SLC6A17,SLC6A3,SLIT1,SMAD1,SMAD9,SOX2,SOX6,SPHK1,SPTBN2,SPTBN4,STAT3,STK3,STXBP3,SUDS3,SYPL2,SYT1,SZT2,TAF1,TBR1,TBX1,TCTN1,TENM4,TFAP2A,TIMP4,TMEM57,TOP2B,TRPC4,TSC1,TTBK1,TTC21B,TWSG1,TYRO3,UNCX,UQCRQ,VAX1,VLDLR,WASF3,WNT2,WNT2B,WNT7A,XRN2,YWHAQ,ZEB1,ZEB2,ZIC1,ZIC2	MammalFishAncestor	169.976
GO.Biological.Process	GO:0044065	regulation.of.respiratory.system.process	69	3.473297e-174	4.486458e-170	6.502113e-172	3.952009e+0	ATP1A2,FTO,GLRA1,GLS,GSX2,MTG2,NLGN2,NLGN3,PBX3,PHOX2B,TSHZ3	MammalFishAncestor	169.348
GO.Biological.Process	GO:0030182	neuron.differentiation	70	7.683350e-173	9.924583e-169	1.417798e-170	1.271946e+0	ABI1,ADGRB3,ADM,AGRN,ALDH1A2,AMIGO1,ANK3,ANKS1A,ARF4,ARFGEF1,ARX,ATL1,ATP7A,ATP8B1,AUTS2,AXIN1,B4GAT1,BAIAP2,BARHL2,BICDL1,BLOC1S5,BOC,C12orf57,CAMSAP1,CAMSAP2,CCSAP,CDH23,CDH4,CDKL3,CELSR2,CEP290,CHD5,CHN1,CLMN,CLN5,CNP,CNTNAP1,COPS2,CPNE1,CRB1,CTHRC1,CTTN,CUL4B,CYFIP1,DAG1,DBX1,DCLK1,DCLK2,DICER1,DLG4,DLL4,DLX1,DLX2,DLX5,DMRT3,DNMT3A,DOCK7,DPYSL4,DRGX,DSCAML1,DYNC2H1,EFNA2,EIF2AK4,EMX2,EN2,EPHA4,ERCC2,EVX1,EYA1,FARP2,FAT4,FEZF1,FGF20,FGF8,FIG4,FOLR1,FOXA2,FOXB1,FOXD1,FOXN4,FRY,FRYL,FSCN2,FYN,FZD10,FZD8,GAB2,GABRB2,GATA3,GDF7,GLDN,GLI2,GLI3,GNAO1,GNAT1,GNAT2,GP5,GSK3B,GSX1,GSX2,HDGFL3,HELT,HERC1,HOXC10,HOXC8,HOXD1,HOXD10,HOXD9,ID2,IER2,IMPACT,INHBA,INSM1,IRS2,IRX5,ISL2,JAG1,KCNIP2,KIDINS220,KIF5A,KIF5B,KIF5C,KNDC1,LAMA2,LAMB1,LAMB2,LDB1,LEF1,LGI1,LHX1,LHX3,LHX4,LHX9,LLGL1,LMO4,LMX1B,LRP12,LRTOMT,MAP2,MAP2K1,MAPK10,MAPK8,MATN2,MCF2,MEF2C,MEGF8,MICALL2,MNX1,MTR,MYEF2,MYO7A,MYOC,MYT1L,NAGLU,NCDN,NDEL1,NEDD4,NEUROD2,NKD1,NKX2-1,NKX2-2,NKX2-8,NKX6-1,NKX6-2,NLGN3,NOTCH1,NR2E1,NR2E3,NR4A2,NR4A3,NRCAM,NRP2,NRXN1,NTN1,NTN4,OGDH,OMG,ONECUT2,OTP,OTX2,PACSIN1,PAK1,PAPD4,PARD3,PAX2,PAX6,PBX3,PCSK9,PDE6C,PDZD7,PHOX2A,PHOX2B,PIK3CB,PIK3CD,PITX2,PITX3,PLCG1,PLXNB3,POSTN,POU3F2,POU4F1,POU4F2,POU4F3,PPP1CC,PPP1R9A,PPP3CB,PREX2,PRKCA,PRKCQ,PRKCZ,PROX1,PROX2,PTCH1,PTPRF,PTPRZ1,RAB10,RAB11A,RAB35,RAB3A,RAP1GAP,RAPGEF2,RELN,RERE,RND1,RNF165,RORA,RTN4,RTN4RL1,RUNX3,SALL1,SALL3,SCARF1,SDK2,SEMA3B,SEMA3F,SEMA5B,SEPT2,SH3GL2,SHANK1,SHH,SHTN1,SIX1,SKOR1,SLC11A2,SLC1A3,SLC44A4,SLC4A10,SLC9A6,SLIT1,SLITRK3,SPTA1,SPTAN1,SPTBN1,SPTBN2,SPTBN4,SS18L1,STAT3,STK11,STK24,STK25,STMN3,STRN,SZT2,TBCE,TBR1,TCTN1,TENM1,TENM2,TENM3,TENM4,THOC2,TMEM106B,TOP2B,UBB,UBE4B,UCN,ULK1,UNCX,UNK,UQCRQ,USH1C,USH2A,USP33,USP9X,VAX1,VCL,VLDLR,WASF1,WASL,WDPCP,WEE1,WNT2,WNT2B,WNT5B,WNT7A,XRN2,ZEB2,ZNF521	MammalFishAncestor	168.003
GO.Biological.Process	GO:0048562	embryonic.organ.morphogenesis	71	6.959942e-172	8.990157e-168	1.266219e-169	1.564378e+0	ACVR1,ALDH1A3,ALX3,ARID1A,AXIN1,BBS5,CCDC39,CEP290,CHRNA9,COL11A1,COL2A1,CTHRC1,DLX2,DLX5,DLX6,DSCAML1,DVL2,EYA1,FBN1,FBN2,FGF8,FOLR1,FOXL2,FOXN4,FZD6,GATA3,GJB6,GLI1,GLI2,GLI3,GSC,HMX2,HMX3,HNF1B,HOXA1,HOXA11,HOXA3,HOXA5,HOXA6,HOXA7,HOXB1,HOXB2,HOXB3,HOXB4,HOXB5,HOXB6,HOXB7,HOXB8,HOXC11,HOXC4,HOXC9,HOXD10,HOXD3,HOXD4,HOXD9,HYAL1,ID2,INSIG1,IRX5,KDM2B,LHX1,MED12,MEF2C,MEGF8,MIB1,MICAL2,MKKS,MYCN,MYF5,MYO15A,MYO3A,MYO3B,MYO7A,NAGLU,NIPBL,NODAL,NOTCH1,NPHP3,NR4A3,NTN1,OSR2,OTX1,PAX2,PAX6,PDGFRA,PDZD7,PITX2,PKD2,POU4F3,PRKRA,PROX1,RARB,RBP4,RYR2,SALL1,SETD2,SHH,SHOX2,SIX1,SIX2,SIX3,SIX4,SLC39A1,SLC44A4,SMAD3,SOX18,SP3,TBX1,TBX2,TCAP,TCF7,TFAP2A,TGFB3,TSHZ1,USH1C,WDPCP,WDR19,ZEB1,ZIC1	MammalFishAncestor	167.046
GO.Biological.Process	GO:0050954	sensory.perception.of.mechanical.stimulus	72	1.049636e-171	1.355815e-167	1.883076e-169	1.805215e+0	ADGRV1,ATP8B1,BARHL1,CACNA1D,CDH23,CHRNA9,COCH,COL11A1,COL11A2,COL1A1,COL2A1,DIAPH1,DRGX,EYA1,FBXO11,FYN,GABRB2,GJB2,GJB6,GPX1,HEXB,HOMER2,HOXA1,ICAM1,KIT,LOXHD1,LRIG2,LRP2,LRTOMT,MBP,MKKS,MYO15A,MYO3A,MYO3B,MYO6,MYO7A,NAV2,NIPBL,OTOF,OTOGL,P2RX2,PAX3,PDZD7,PIEZO2,POU4F2,POU4F3,RAB3A,ROR1,SCN1A,SIX1,SLC1A3,SLC26A5,SPTBN4,SRRM4,TBX1,TFAP2A,TUB,UCN,USH1C,USH2A,USP53	MammalFishAncestor	166.868
GO.Biological.Process	GO:0071383	cellular.response.to.steroid.hormone.stimulus	73	1.403226e-169	1.812547e-165	2.482941e-167	1.743845e+0	ABCB4,ACOD1,ARID1A,ATP1A2,CCNE1,CRH,ESR1,ESRRB,ESRRG,FECH,FKBP4,FLT3,FOXO3,GJB2,HNF4G,ICAM1,LEF1,MED1,MED12,MED13,MED14,MED16,NEDD4,NR1I2,NR2C1,NR2E1,NR2E3,NR2F1,NR2F2,NR3C2,NR4A2,NR4A3,NR5A1,NR5A2,NR6A1,PAQR5,PAQR9,PIAS1,PLPP1,POU4F2,PPARG,RAN,RARB,RHOXF1,RORA,RPL32,RPS6KB1,RXRB,SERPINF1,TAF7,TFAP4,THRAP3,UBR5,URI1,WBP2,ZFP36L2	MammalFishAncestor	164.742
GO.Biological.Process	GO:0001501	skeletal.system.development	74	1.555691e-169	2.009486e-165	2.715522e-167	1.438683e+0	ABI1,ACP2,ACVR2A,ALPL,ALX3,ANKRD11,ANXA2,ASXL1,ATP7A,AXIN1,BBS2,BMP3,BMP6,BMP8A,CHSY1,CMKLR1,COL11A1,COL11A2,COL12A1,COL19A1,COL1A1,COL1A2,COL2A1,COMP,CSRNP1,DHRS3,DLX1,DLX2,DLX5,DLX6,DMRT2,DSCAML1,EP300,EYA1,FAT4,FBN1,FBN2,FBXW4,FGF8,FOXN3,FOXP1,GJA5,GLI2,GLI3,GSC,HAPLN4,HEXB,HHIP,HOXA1,HOXA10,HOXA11,HOXA13,HOXA3,HOXA5,HOXA6,HOXA7,HOXB1,HOXB2,HOXB3,HOXB4,HOXB5,HOXB6,HOXB7,HOXB8,HOXB9,HOXC10,HOXC11,HOXC4,HOXC5,HOXC6,HOXC8,HOXC9,HOXD1,HOXD10,HOXD12,HOXD13,HOXD3,HOXD4,HOXD8,HOXD9,HYAL1,HYAL2,HYAL3,INHA,INPPL1,INSIG1,IRX5,KIAA1217,KIT,LHX1,LRRK1,MATN1,MATN3,MED1,MED12,MEF2C,MEGF8,MEIS1,MKKS,MMP2,MYCN,MYF5,MYOC,NAB1,NCAN,NIPBL,NODAL,NOV,OSR2,PAPSS1,PAX1,PCSK5,PDGFRA,PITX1,PITX2,PKD1,POSTN,PRKRA,PTPN6,RAB23,RAI1,RARB,RBP4,RHOA,RUNX3,RYR1,SETD2,SFRP2,SHH,SHOX,SHOX2,SIX1,SIX2,SIX4,SLC38A10,SLC39A1,SMAD1,SMAD3,SMAD9,SOX6,SP3,SP5,SPARC,SPNS2,SULF1,SULF2,TBX1,TBX4,TFAP2A,TGFB3,TLL1,TRAPPC2,TRPV4,UNCX,USP1,WDR19,WDR48,WFIKKN2,WNT2B,WNT5B,WNT7A,ZEB1	MammalFishAncestor	164.697
GO.Biological.Process	GO:0009168	purine.ribonucleoside.monophosphate.biosynthetic.process	75	2.432860e-169	3.142525e-165	4.190034e-167	3.325428e+0	ADK,ADSS,ADSSL1,AK5,AK9,AMPD2,AMPD3,APRT,ATIC,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP5S,ATP6V0A1,ATP6V0A2,IMPDH2,LHPP,PAICS,PPAT,PRPS2,SLC25A13,STOML2	MammalFishAncestor	164.503
GO.Biological.Process	GO:0008283	cell.proliferation	76	5.623748e-169	7.264195e-165	9.558152e-167	1.382551e+0	ABCB1,ACVR2A,AKT1,APPL1,ARIH2,ARX,ASCC3,BHLHE41,BOK,BRCA2,BTRC,BUB1B,C5AR1,CBFA2T3,CD180,CD40LG,CDK11B,CDK19,CDK3,CDK5RAP3,CEP120,CHRM4,CHRM5,COL4A3BP,COPS2,CSE1L,CSPG4,DACH1,DAZAP1,DCHS2,DCT,DCTN2,DLX5,DMRT1,DNPH1,DOCK7,DOCK8,DPH1,DTYMK,DVL2,EDNRA,EMX2,ENPEP,ERCC2,ESR1,EVI5,F2RL1,FAM83A,FAP,FAT4,FGF5,FGF8,FKBP1B,FLT3,FSCN1,FYN,FZD6,GAS6,GCG,GFI1B,GLI2,GLI3,GNAI2,GNAT1,GNB1,GPX1,H3F3B,HDGFL3,HHIP,HNF1B,HOXB4,ID2,IMPDH2,INSIG1,IRS2,ITGB1BP1,KALRN,KAT2A,KIF14,KIF1A,KIT,KITLG,LEF1,LGI1,LHX9,LRP1,LRP2,MAP2K1,MAP3K20,MECOM,MED1,MEF2C,MET,MKI67,MNAT1,MT3,NDE1,NDEL1,NKAP,NKX6-1,NOTCH1,NOV,NR4A3,NR6A1,NRARP,OCA2,OGFOD1,OSR2,PA2G4,PAK5,PAX1,PDK1,PDS5B,PIK3CB,PITX2,PLCE1,PLCL2,PLXNB2,POLA1,POLR3G,POU3F2,POU3F3,PPP3CB,PRG4,PRKCD,PRKDC,PROK2,PROX1,PTCH1,PTPN6,RAB10,RAF1,RASGRP4,RERE,RORA,SALL4,SART3,SATB1,SERPINF1,SFRP2,SHH,SIX1,SIX2,SIX3,SLC39A5,SMAD1,STAT1,STAT3,TBCK,TBX1,TCF7L2,TENM4,TFDP1,TGFBR3,TNFSF11,TSPAN1,TUSC2,UBR5,UNCX,USP13,VTI1B,WASHC1,WDR12,WNT2,WNT2B,WNT7A,ZEB1,ZEB2,ZFP36L2,ZMYND11,ZNF503	MammalFishAncestor	164.139
GO.Biological.Process	GO:0097435	supramolecular.fiber.organization	77	4.538696e-168	5.862634e-164	7.613810e-166	1.617446e+0	ABI1,ACTA1,ACTC1,ACTG1,ADAMTS14,AGFG1,AKAP9,ANXA2,ARHGAP12,ARPC3,ARPC5L,ATP7A,AXIN1,BAIAP2,BAIAP2L1,CAPN3,CASQ1,CCSAP,CEP120,CGNL1,CLASP1,COBLL1,COL11A1,COL11A2,COL12A1,COL1A1,COL1A2,COL2A1,CORO7,CSNK1D,CTTN,DES,DIAPH1,DNAJB6,DYNC1H1,EPPK1,ERMN,FLNA,FRY,FRYL,FSCN1,FSCN2,HDGFL3,INPPL1,IQGAP2,JMY,KLHL41,KRT8,LMOD2,LTBP2,MAP7D3,MICAL2,MICALL2,MSRB1,MYBPC1,MYBPC2,MYBPC3,MYBPHL,MYH11,MYH3,MYL2,MYOM1,MYOM2,MYOZ1,MYOZ2,MZT1,NDE1,NDEL1,NF1,NIN,NUMA1,OBSCN,OBSL1,P3H4,PACSIN1,PDGFRA,PKP1,PPP1R9A,PREX1,PROX1,RAB11A,RHOA,RHOF,RND1,SERPINF2,SFRP2,SHH,SHROOM1,SHTN1,SIX4,SLAIN2,SLK,SPIRE1,SPTA1,STMN3,SWAP70,TCAP,TMSB4X,TNNT2,TPM1,TRPV4,TUBG1,TUBG2,TUBGCP4,TUBGCP5,TUBGCP6,USH1C,VIL1,WASF1,WASF3,WASHC1,WASL,WHAMM,WIPF1,ZNF207	MammalFishAncestor	163.232
GO.Biological.Process	GO:0006886	intracellular.protein.transport	78	1.294736e-167	1.672410e-163	2.144116e-165	1.480831e+0	ADPRHL1,AHCYL1,AKAP12,AKAP6,AKT1,AP1G1,AP3B1,AP3B2,AP3M1,AP4S1,APPBP2,ATG4B,ATG4C,BCAP31,CACNG3,CDC37,CEP131,CLIP1,CLTC,COPB1,COPB2,COPZ1,COPZ2,CRB1,CSE1L,CTTN,DAG1,DERL1,DNAJC19,DNLZ,DYNC2H1,DYNC2LI1,EIF5A,ERBIN,EVI5,FAM53B,GABARAP,GCC2,GNPTAB,GPN3,GRPEL1,GRTP1,HEATR3,HERC2,HSP90AA1,HSPA4,ICK,ICMT,IFT122,IFT43,IFT80,IFT81,IFT88,IMMP1L,IMMP2L,IPO9,KIF17,KIF1A,KIF3A,KIF3B,KIF3C,KPNA2,KPNA4,LAMP2,LARS,LTBP2,MFF,MFN2,MT3,MTX2,MTX3,MYO6,MYO7A,NAPG,NCKIPSD,NDUFA13,NEDD4,NFKBIA,NPLOC4,NUP133,NUP188,NUP214,PACS1,PAM16,PAN3,PARD3,PEX14,PEX2,PEX5,PEX5L,PHB2,PIK3R4,PKD1,PMM1,PMPCA,RAB27A,RABGAP1,RABL2B,RAN,RANBP1,RANBP2,RERE,RHOB,RILPL1,RILPL2,RIMS2,RPL10,RPL19,RPL21,RPL22,RPL27A,RPL30,RPL32,RPL35,RPL39,RPL4,RPL41,RPL5,RPL9,RPLP1,RPS10,RPS15,RPS2,RPS26,RPS3A,SAR1A,SAR1B,SEC23IP,SEC24A,SEC24C,SEC24D,SEC63,SELENOS,SIX2,SIX3,SNF8,SNUPN,SNX11,SNX2,SNX31,SNX33,SPTBN1,SRP14,SRP54,SRP68,SRP72,SSX2IP,STAM2,STAT3,STX10,STX17,STX2,STX8,SYNRG,TBC1D13,TBC1D14,TBC1D4,TBC1D5,TBCK,TLK1,TNPO1,TNPO3,TOB1,TOM1L2,TOMM20,TPR,TRAM1,TSC2,TTC21A,TTC21B,TTC30A,TTC30B,UBA52,VPS26A,VPS29,VPS39,VPS41,VTI1A,VTI1B,WDR19,WDR34,XPO1,XPO4,YWHAQ,YWHAZ,ZFYVE9	MammalFishAncestor	162.777
GO.Biological.Process	GO:0048878	chemical.homeostasis	79	1.299006e-167	1.677926e-163	2.123957e-165	1.363755e+0	ABCA1,ABCB4,ABCB7,ABCC8,ABCG2,ABCG5,ABCG8,ACACA,ADCY5,ADCY6,ADCY7,ADCY9,ADIPOR2,ADM,ADRA2A,AGTR1,AKT1,ANGPTL3,ANGPTL8,ANK2,ANK3,APOB,AQP9,ATOX1,ATP13A3,ATP1A2,ATP1A4,ATP2A2,ATP2C1,ATP5B,ATP6V0A1,ATP6V0A2,ATP6V1A,ATP6V1D,ATP6V1F,ATP6V1G3,ATP7A,BCAP31,BHLHA15,BMP6,BOK,C5AR1,C5AR2,CACNA1A,CACNA1C,CACNA2D1,CACNB3,CALCA,CALCB,CAMK2D,CCDC22,CCR10,CDH23,CFTR,CHRNA9,CLIC4,CLN5,CNNM2,COL4A3BP,CRH,CRTC2,CYBRD1,DDIT3,DLG4,DMXL1,DMXL2,DRD3,EDNRA,EDNRB,EIF2AK1,EIF5A,EIF5A2,ELANE,ENDOG,ERO1B,ESR1,F2R,F2RL1,F2RL2,FABP3,FASLG,FBXL5,FKBP1B,FOXO3,G6PC2,GALR1,GAS6,GCLC,GCLM,GJB6,GLP1R,GNAT2,GNB1,GPI,GPR12,GPR157,GPR21,GPR6,GPR89B,GRHL1,GRM1,HACD3,HCRT,HECTD4,HEXB,HFE,HK1,HKDC1,HOMER1,HOMER2,HRH4,HYAL2,ICAM1,IRS2,ISCU,ITPR1,ITPR2,ITPR3,KCNJ11,KCNMA1,KL,LAMTOR1,LDLR,LDLRAP1,LEPR,LETMD1,LIPC,LPAR3,LPCAT1,MBD5,MED13,MEN1,MET,MT2A,MT3,MT4,MTNR1B,NOX1,NR5A2,OGT,PAX2,PAX6,PCSK9,PDGFRA,PDK2,PDK3,PDK4,PDX1,PFKM,PIK3CB,PIK3R2,PKD1,PKD2,PLCE1,PLSCR3,POLG,POMC,POU3F3,PPARG,PRKACB,PRKAR2A,PRKCB,PROK2,PTCH1,PTPN2,PTPRN,PTPRN2,PYGL,RAB11A,RAB11FIP2,RAB20,RAF1,RANBP2,RAP1A,RASA3,RBP4,RHCG,RIC3,RORA,RYR1,RYR2,RYR3,SCN7A,SERPINF1,SFN,SFXN3,SIN3A,SKP1,SLC11A2,SLC24A1,SLC24A5,SLC26A5,SLC26A6,SLC2A4,SLC30A1,SLC30A9,SLC35G1,SLC39A10,SLC39A5,SLC39A7,SLC4A1,SLC4A10,SLC4A8,SLC8A2,SLC9A6,SMAD3,SRI,STAT1,STAT3,STK11,STOML2,SWAP70,SYPL2,TCF7L2,THADA,TM9SF4,TMEM165,TNFSF11,TRPC1,TRPC4,TRPV4,TWNK,UBA52,UBB,UNC13B,VPS33A,ZNF236	MammalFishAncestor	162.775
GO.Biological.Process	GO:0051345	positive.regulation.of.hydrolase.activity	80	3.517130e-167	4.543077e-163	5.678846e-165	1.392519e+0	ACAP1,ACVR1C,ADGRB3,ADPRHL1,ADRB1,AGAP5,AGFG1,AGRN,AGTR1,AKAP6,AKT1,APOPT1,ARF4,ARFGAP1,ARHGAP10,ARHGAP12,ARHGAP15,ARHGAP18,ARHGAP19,ARHGAP21,ARHGAP22,ARHGAP24,ARHGAP29,ARHGAP45,ARHGAP9,ARHGDIG,ARHGEF10,ARHGEF16,ARHGEF38,ARHGEF6,ARL1,ASAP2,AXIN1,BCAP31,BCAS3,BCL2L10,BNIP2,BOK,C5AR1,CASP7,CASP8AP2,CCL20,CDC42EP4,CDKL5,CHN1,CORO1C,DDX3X,DENND1B,DEPDC7,DHX9,DIABLO,DNAJA2,DNAJB2,DNAJB4,DNAJB6,DNAJC24,DNAJC7,DOCK1,DOCK4,DOCK7,DOCK8,DOCK9,DVL2,DYNC1I1,DYNC1I2,EDNRA,EGLN3,EPHA4,ESR1,EVI5,F2R,F2RL1,FAM13A,FASLG,FLT1,FN1,FOXL2,FZD10,GAPVD1,GIT1,GIT2,GNAO1,GNAT1,GNB5,GRTP1,GSK3B,HACD3,HIP1R,ICAM1,IQSEC1,ITGA6,KALRN,KIT,LARS,LIMS1,LLGL1,LLGL2,MAPK12,MAPK8,MBP,MEF2C,MSH6,MTCL1,MYBPC3,MYO9A,NDEL1,NDUFA13,NF1,NODAL,NPNT,NPRL2,P2RX1,PCOLCE2,PDCD5,PDGFRA,PGAM5,PIK3R2,PKP4,PLCB2,PPARG,PREX1,PREX2,PRKCD,PRKCZ,PRKD2,PRTN3,PSMD14,RAB3A,RAB4A,RABGAP1,RALBP1,RALGAPA1,RALGAPA2,RANBP1,RANBP2,RANGAP1,RAP1A,RAP1GAP,RAPGEF2,RAPGEF6,RASA1,RASA3,RASGEF1B,RASGRP2,RASGRP3,RASGRP4,RGS11,RGS12,RGS22,RHOA,RIC8B,RIN1,RPS27L,RSU1,RYR2,SENP1,SFRP2,SIPA1L1,SLC39A10,SMAD3,ST18,STARD13,STAT3,STXBP5,TANK,TBC1D13,TBC1D14,TBC1D4,TBC1D5,TBCK,TFAP4,TIAM2,TMSB4X,TNNT2,TPM1,TSC1,TSC2	MammalFishAncestor	162.343
GO.Biological.Process	GO:0051093	negative.regulation.of.developmental.process	81	1.437299e-166	1.856559e-162	2.292048e-164	1.317249e+0	ABCA1,ABCC8,ACVR1C,ADAMTS9,ADCY6,ADGRB3,ADGRV1,ADRB1,ANKRD26,ANXA2,ASXL1,AXIN1,BAG5,BBS2,BHLHA15,BHLHE41,BRCA2,C16orf45,CAPN3,CDK12,CDKL3,CERS2,CHADL,CLASP1,COL4A2,CORO1C,CTDP1,CTR9,CUL4A,CYLD,DACT3,DDIT3,DDX6,DENND5A,DICER1,DLL4,DLX1,DLX2,DNM3,DRD3,ECM1,EDNRB,EIF2AK4,EPHA4,ESRRB,FASLG,FBN1,FGF8,FIG4,FKBP4,FOXA2,FOXO3,FSTL4,GAS6,GATA3,GBP1,GFI1,GLI2,GLI3,GORASP1,GPS2,GSK3B,H1FOO,HIST1H4A,HIST1H4B,HIST1H4C,HIST1H4D,HIST1H4E,HIST1H4F,HIST1H4H,HNF1B,HOXA5,HOXA7,HOXA9,HOXB8,HSPG2,HYAL3,ID2,IFT122,IL17D,INHA,INHBA,INPP5F,INSIG1,IRX3,ISL2,ITGB1BP1,JAG1,JDP2,KANK1,KCTD11,KDM4A,LDB1,LDLRAD4,LEF1,LRIG2,LRP1,LUC7L,MAP2K5,MAPK11,MARCH5,MCF2,MED1,MEIS1,MEIS2,MEN1,MIB1,MT3,MYCN,N4BP2L2,NEUROD2,NF1,NFE2L2,NFKBIA,NKD1,NKX2-1,NKX2-2,NKX6-1,NKX6-2,NLGN3,NODAL,NOTCH1,NOV,NPHP3,NPPB,NR2E1,NR2F1,NR5A1,NRARP,NTN1,OMG,P2RY12,PAK1,PAQR3,PAX2,PAX6,PDCD4,PDE3B,PGK1,PHB2,PHOX2B,PITX3,PLAC8,PLPP7,POSTN,POU4F2,PPARG,PPP2CA,PRDM6,PRKACB,PRKDC,PTBP1,PTCH1,PTPN2,PTPRG,PTPRS,RAI1,RAPGEF2,RARB,RBM15,RBP4,RFX4,RGCC,RHOA,RNF6,ROCK1,RORA,RTN4,RTN4RL1,SAV1,SEMA3F,SERPINF1,SEZ6,SFRP2,SHH,SIX1,SIX2,SIX3,SIX4,SKOR1,SLIT1,SMAD3,SORT1,SOX2,SOX6,SPARC,SPART,SPDEF,SRGN,STAB1,STARD13,STAT1,STAT3,STAT5B,STK11,STK3,SULF1,SUZ12,TBX1,TBX2,TBX21,TCTA,THBS4,THOC2,TOB1,TOB2,TP73,TRIM11,TRIO,TRPV4,TSC1,TWSG1,USH2A,USP19,VASH1,VASN,VAX1,WNT7A,WT1,WWC1,ZADH2,ZBTB46,ZEB1,ZFP36L2,ZFPM2,ZHX2,ZNF536	MammalFishAncestor	161.731
GO.Biological.Process	GO:0098751	bone.cell.development	82	1.621773e-165	2.094844e-161	2.554688e-163	3.588088e+0	ABI1,ANXA2,EP300,FOXP1,KIT,LRRK1,MED1,MEIS1,PTPN6	MammalFishAncestor	160.679
GO.Biological.Process	GO:0009887	animal.organ.morphogenesis	83	3.183241e-164	4.111792e-160	4.953967e-162	1.296719e+0	ACTA1,ACTC1,ACVR1,ADAMTS16,ADM,AKT3,ALDH1A2,ALDH1A3,ALPL,ALX3,ANKRD11,ARID1A,ASXL1,ATF2,AXIN1,BBS2,BBS5,BHLHE41,BMP6,BTRC,C12orf57,CCDC39,CDX2,CELA1,CEP290,CHRNA9,CHSY1,COL11A1,COL1A1,COL1A2,COL2A1,COL4A3BP,COL9A1,COMP,CPE,CRB1,CRKL,CRYGB,CSF3R,CSRNP1,CTHRC1,CTNNBIP1,CYP7B1,DAG1,DHRS3,DLG5,DLL4,DLX1,DLX2,DLX5,DLX6,DSCAML1,DVL2,EDAR,EP300,ESR1,EYA1,FANCC,FASLG,FAT4,FBN1,FBN2,FGF16,FGF8,FHL1,FOLR1,FOXD1,FOXL2,FOXN3,FOXN4,FOXO3,FRAS1,FSCN2,FZD6,GAMT,GATA3,GATA6,GCNT1,GCNT3,GDF7,GJA5,GJB6,GLI1,GLI2,GLI3,GNAT1,GNAT2,GSC,GSX2,HHIP,HMX2,HMX3,HNF1B,HOXA1,HOXA11,HOXA3,HOXA5,HOXA6,HOXA7,HOXB1,HOXB13,HOXB2,HOXB3,HOXB4,HOXB5,HOXB6,HOXB7,HOXB8,HOXC11,HOXC13,HOXC4,HOXC8,HOXC9,HOXD10,HOXD11,HOXD13,HOXD3,HOXD4,HOXD8,HOXD9,HYAL1,HYAL2,ID2,IFT122,INHBA,INPPL1,INSIG1,IRX1,IRX2,IRX3,IRX4,IRX5,ITGA6,ITGB4,JAG1,KDM2B,KDM5B,KLHL10,LAMB1,LEF1,LHX1,LHX3,LHX4,LHX9,LRP2,MAP2K1,MATN1,MED1,MED12,MEF2C,MEGF11,MEGF8,MEIS1,MFN2,MIB1,MICAL2,MKKS,MMP2,MTOR,MYBPC3,MYCN,MYF5,MYF6,MYL2,MYO15A,MYO3A,MYO3B,MYO5A,MYO7A,NAB1,NAGLU,NEDD4,NF1,NIPBL,NKD1,NKX2-1,NKX6-1,NODAL,NOTCH1,NPHP3,NPNT,NR2E3,NR4A3,NR5A2,NRP2,NTN1,ONECUT2,OSR2,OTX1,PARVA,PAX1,PAX2,PAX3,PAX6,PAX9,PDCD4,PDE6C,PDGFRA,PDX1,PDZD7,PGF,PHB2,PITX2,PITX3,PKD1,PKD2,PLXND1,POU4F1,POU4F3,PRKRA,PROX1,PROX2,PTCH1,RAB23,RARB,RBM15,RBP4,RS1,RTN4,RYR1,RYR2,SALL1,SAV1,SCN10A,SCN5A,SDC1,SDK1,SDK2,SETD2,SFRP2,SHH,SHOX2,SIX1,SIX2,SIX3,SIX4,SIX6,SLC39A1,SLC44A4,SLC4A10,SLIT1,SMAD3,SMAD6,SMARCC1,SMARCD3,SOX18,SP3,SP5,STAT3,STK40,STX2,TBR1,TBX1,TBX2,TBX4,TCAP,TCF7,TENM3,TFAP2A,TGFB3,TGFBR3,TLE3,TNFSF11,TNNC1,TNNI1,TNNT2,TPM1,TREH,TRPV4,TSHZ1,TWSG1,UBE4B,UNCX,USH1C,WDPCP,WDR19,WDR48,WDR72,WNT2,WNT2B,WNT7A,WT1,XIRP2,ZEB1,ZFPM2,ZIC1	MammalFishAncestor	159.386
GO.Biological.Process	GO:0016458	gene.silencing	84	3.711507e-164	4.794154e-160	5.707326e-162	2.213536e+0	AGO1,AGO3,AGO4,ARID1A,ASZ1,BAHCC1,BAZ2A,CNOT7,CNOT9,DGCR8,DHX9,DICER1,DNMT1,DNMT3A,H3F3B,HAT1,HENMT1,HIST1H2AB,HIST1H2AC,HIST1H2AD,HIST1H2AE,HIST1H3A,HIST1H3B,HIST1H3C,HIST1H3D,HIST1H3E,HIST1H3F,HIST1H3G,HIST1H4A,HIST1H4B,HIST1H4C,HIST1H4D,HIST1H4E,HIST1H4F,HIST1H4H,KMT2D,PABPC1,PIWIL1,PPM1D,PRKRA,PUM1,PUM2,RAN,RIF1,SMAD1,SMAD3,SOX6,STAT3,SUPT6H,TDRD1,TNRC18,TNRC6A,UBE2B,ZC3H7B	MammalFishAncestor	159.319
GO.Biological.Process	GO:0014706	striated.muscle.tissue.development	85	2.104745e-162	2.718699e-158	3.198470e-160	1.570467e+0	ACTA1,ACTC1,ACVR1,ADAMTS9,ALDH1A2,ARID1A,ASB2,BCL9,BCL9L,CASQ1,CHRNA1,COL11A1,COL19A1,COPS2,DLL4,DNER,EMD,EP300,EYA1,FLNB,FOS,FOXL2,FOXN2,FOXP2,GATA6,GJA5,GPX1,GTF3C5,HOMER1,HOXD10,HOXD9,KAT2A,KDM6B,KLF5,KLHL40,KLHL41,LRP2,MED1,MEF2C,MSC,MTOR,MYBPC3,MYF5,MYF6,MYH11,MYL2,MYL6B,MYOM1,MYOM2,NDUFV2,NEURL1,NEXN,NF1,NOTCH1,NPPA,NPPB,NR2F2,OBSL1,P2RX2,PDGFRA,PHOX2B,PITX1,PITX2,POU4F1,PROX1,PROX2,RARB,RBP4,RYR1,RYR2,SGCG,SHH,SIX1,SIX4,SMAD1,SOX6,SRPK3,STAC3,TAZ,TBX2,TCAP,TENM4,TGFBR3,TNNC1,TNNI1,TNNT2,TPM1,TSC1,UBE4B,VAX1,WNT2,WT1,XIRP2,ZBTB18,ZFPM2	MammalFishAncestor	157.566
GO.Biological.Process	GO:0021913	regulation.of.transcription.from.RNA.polymerase.II.promoter.involved.in.ventral.spinal.cord.interneuron.specification	86	3.847196e-162	4.969423e-158	5.778399e-160	6.394252e+0	EVX1,NKX6-1,NKX6-2,PAX6	MammalFishAncestor	157.304
GO.Biological.Process	GO:0007605	sensory.perception.of.sound	87	1.835044e-160	2.370326e-156	2.724513e-158	1.829599e+0	ADGRV1,ATP8B1,BARHL1,CACNA1D,CDH23,CHRNA9,COCH,COL11A1,COL11A2,COL1A1,COL2A1,DIAPH1,EYA1,FBXO11,GABRB2,GJB2,GJB6,GPX1,HEXB,HOMER2,HOXA1,ICAM1,KIT,LOXHD1,LRIG2,LRP2,LRTOMT,MBP,MKKS,MYO15A,MYO3A,MYO3B,MYO6,MYO7A,NAV2,NIPBL,OTOF,OTOGL,P2RX2,PAX3,PDZD7,POU4F2,POU4F3,ROR1,SIX1,SLC1A3,SLC26A5,SPTBN4,SRRM4,TBX1,TFAP2A,TUB,UCN,USH1C,USH2A,USP53	MammalFishAncestor	155.625
GO.Biological.Process	GO:0009749	response.to.glucose	88	1.814232e-159	2.343443e-155	2.663004e-157	2.043399e+0	ACVR1C,ATG7,EIF2B2,ENDOG,ENSA,FKBP1B,FOXO3,GAS6,GCLC,GCLM,GJB6,HNF1B,ICAM1,IRS2,KCNJ11,MEN1,NKX2-2,NKX6-1,PAX2,PDK3,PDX1,POLG,PTPRN,PTPRN2,RAB11FIP2,RAF1,RAP1A,RPS6KB1,SELENOS,SERPINF1,SIN3A,SREBF1,TCF7L2,TWNK,UNC13B,ZNF236	MammalFishAncestor	154.63
GO.Biological.Process	GO:0009725	response.to.hormone	89	3.728416e-159	4.815995e-155	5.411230e-157	1.369917e+0	AANAT,ABCB4,ABCC8,ACACA,ACAT1,ACOD1,ACR,ACSL1,ACTA1,ACVR1C,ADCY5,ADCY6,ADCY7,ADCY9,ADIPOR2,ADM,ADRA2A,AGTR1,AGTRAP,AHCYL1,AKT1,ALPL,ANGPTL3,ANXA2,ANXA3,APOB,APPL1,APRT,ARID1A,ATP1A2,ATP6V0A1,ATP6V0A2,ATP6V1A,ATP6V1D,ATP6V1F,ATP6V1G3,BAIAP2,BAIAP2L1,BBS2,BMP6,BRIP1,CATSPER3,CCNE1,COL1A1,CPEB2,CRH,CTSS,CYFIP1,DAG1,DHCR24,EIF2B2,EIF4EBP2,EIF5A,ENSG00000278139,ESR1,ESRRB,ESRRG,FABP3,FBN1,FECH,FGB,FKBP4,FLT3,FOS,FOXO3,FSHR,FYN,GATA6,GCG,GCLC,GCLM,GCNT1,GJB2,GLP1R,GNB1,GNB3,GNB4,GNG4,GNG5,GPI,H3F3B,HADH,HADHA,HNF4G,ICAM1,IDE,IDH1,INHBA,INPPL1,IRS2,JUND,KIT,KL,LATS2,LEF1,LEPR,LHCGR,MARS,MDK,MED1,MED12,MED13,MED14,MED16,MEF2C,MEN1,MKKS,MT3,MTOR,MYO5A,NCOA2,NDEL1,NEDD4,NFE2L2,NKX2-1,NKX2-2,NKX6-1,NOTCH1,NPFFR1,NPPA,NPPB,NR1I2,NR2C1,NR2E1,NR2E3,NR2F1,NR2F2,NR3C2,NR4A2,NR4A3,NR5A1,NR5A2,NR6A1,NSMF,OGT,PAK1,PAQR5,PAQR9,PCSK9,PDE3B,PDK2,PDK4,PDX1,PGF,PIAS1,PIK3R2,PIK3R3,PITX2,PLPP1,POU4F2,PPARG,PPAT,PRKACB,PRKAR2A,PRKCD,PRKCZ,PRKDC,PTGFR,PTGS2,PTPN2,PTPRN,RAB10,RAN,RANGAP1,RARB,RHOXF1,RORA,RPL32,RPS6KB1,RXRB,SCAP,SDC1,SELENOS,SERPINF1,SLC26A5,SLC2A4,SMARCC1,SORT1,SPARC,SREBF1,STAT1,STAT3,STAT5A,STAT5B,STXBP3,TAF7,TBC1D4,TFAP4,TGFB3,TGFBR3,THRAP3,TIMP4,TRPV4,TSC1,TUB,UBR5,UCN,URI1,WBP2,WT1,ZFP36L2,ZNF106	MammalFishAncestor	154.317
GO.Biological.Process	GO:0019637	organophosphate.metabolic.process	90	7.457332e-158	9.632636e-154	1.070293e-155	1.369553e+0	ABHD3,ACAT1,ACLY,ACP6,ADCY5,ADCY6,ADCY7,ADCY9,ADK,ADM,ADSS,ADSSL1,AFG1L,AK4,AK5,AK8,AK9,ALDOC,AMPD2,AMPD3,ANGPTL3,APRT,ASPDH,ATIC,ATM,ATP1A2,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP5S,ATP6V0A1,ATP6V0A2,ATP6V1A,CHPT1,CKM,CLN8,CNP,COX6C,COX7B,COX8C,CPNE1,CROT,CRYL1,DCTD,DGKH,DLD,DLG4,DNPH1,DOLK,DTYMK,DUT,ENO1,ENO2,ENO4,ENPP2,ENSG00000266953,ENSG00000278139,ENTPD8,ERBB3,FGF16,FGF20,FGF5,FGF8,FIG4,FMO1,FMO2,FYN,G6PC2,GALK1,GAPDH,GATA6,GGPS1,GK2,GK3P,GNAI3,GNPAT,GPAT3,GPD2,GPHN,GPI,GPX1,GPX4,H6PD,HADHA,HEXB,HK1,HKDC1,HMGCR,IDH1,IDI1,IDI2,IMPDH2,INPP5A,INPP5E,INPP5F,INPPL1,IP6K2,IRS2,ISYNA1,ITPK1,KCNAB2,KIT,KITLG,KL,KLB,LDHB,LHPP,LIPC,LPCAT1,LPCAT2,LPCAT3,LPGAT1,LPIN2,MAGI3,MBD4,MBIP,MBOAT2,MDH1,MET,MFN1,MTMR14,MTMR7,MVK,MYH3,MYH4,MYH8,NADK,NAXD,NDUFA1,NDUFA12,NDUFA13,NDUFA5,NDUFAF7,NDUFB10,NDUFB5,NDUFS1,NDUFS6,NDUFS7,NDUFV2,NKX2-1,NME4,NMNAT1,NMNAT2,NOX1,NPPA,NPPB,NT5C2,NT5C3B,NT5E,NTHL1,NUDT3,OGDH,OLA1,OSBPL8,PAICS,PAPSS1,PCSK9,PCYT1B,PDE3B,PDE4A,PDE4C,PDE7A,PDE8B,PDGFRA,PFKFB4,PFKM,PGAM4,PGK1,PGM1,PGM3,PI4KA,PIGB,PIGC,PIGK,PIGL,PIGN,PIGO,PIGQ,PIGS,PIGV,PIGY,PIK3AP1,PIK3CB,PIK3CD,PIK3R2,PIK3R3,PIK3R4,PIK3R5,PIK3R6,PIKFYVE,PIP4K2C,PITPNM2,PLA2G4A,PLA2G4B,PLA2G4F,PLCB2,PLCB4,PLCD1,PLCD4,PLCE1,PLCG1,PLD4,PLPP1,PLPP4,PLPPR3,PNPLA8,PNPO,PON1,PPAT,PPIP5K1,PROCA1,PRPS2,PTGS2,PTPN13,PYGL,PYURF,RAB23,RAB4A,RFK,RORA,RPE,RPEL1,RPIA,RRM2B,SAMD8,SBF1,SERINC5,SGMS2,SLC22A13,SLC25A13,SLC35B2,SLC35B3,SLC44A4,SLC5A8,SMUG1,SRD5A3,STARD7,STOML2,SULT6B1,TAMM41,TAZ,TKT,TNFAIP8L3,TPI1,UCKL1,UCN2,UGP2,UMPS,UNG,UPP2,UQCRHL,UQCRQ,ZFYVE21	MammalFishAncestor	153.016
GO.Biological.Process	GO:0035196	production.of.miRNAs.involved.in.gene.silencing.by.miRNA	91	1.689384e-157	2.182177e-153	2.397997e-155	4.026497e+0	AGO1,AGO3,AGO4,DGCR8,DICER1,PRKRA,PUM1,PUM2,SMAD1,SMAD3,ZC3H7B	MammalFishAncestor	152.661
GO.Biological.Process	GO:0042117	monocyte.activation	92	1.274810e-155	1.646672e-151	1.789861e-153	6.655134e+0	ADAM10,AZU1,FOXP1,HYAL2,MT1G	MammalFishAncestor	150.783
GO.Biological.Process	GO:0060341	regulation.of.cellular.localization	93	3.525175e-154	4.553469e-150	4.896203e-152	1.342011e+0	ACSL3,ACTL6A,ADCY5,ADORA2B,ADRA2A,AKAP6,AKT1,ANK2,ANK3,ANXA2,APPL1,ARHGEF16,ARIH2,ARV1,ATP1A2,ATP2A2,BAG3,BAMBI,BAP1,BCAP31,BCAS3,BMF,BMP6,CACNA1C,CAMK2D,CAPN3,CASQ1,CCDC22,CCNE1,CCT4,CD4,CDK5RAP3,CDT1,CEP131,CEP290,CFTR,CLTC,CNIH2,CRH,CTSK,CYFIP1,CYLD,DACT3,DCLK1,DCLK2,DHRS7C,DHX9,DIAPH1,DNAJC13,DPH6,DRD3,DYNC1H1,EDAR,EDEM1,EFCAB7,EMD,ENY2,ERLEC1,F2R,FGF14,FKBP1B,FLNA,FOXA2,FYN,GAB2,GAS6,GBF1,GBP1,GCC2,GCG,GLI3,GLIS2,GLS2,GPM6B,GPR26,GPR27,GPSM2,GSK3B,GSTO1,HCRT,HFE,HMGCR,HTT,HUWE1,HYAL2,ICE1,INSIG1,ITGB1BP1,JUP,KALRN,KANK1,KAT2A,KCNAB2,KCNC4,KCNJ11,KEAP1,KIF5B,LAMP1,LDLRAP1,LRIG2,LRP1,LRRC46,LZTS2,MAD1L1,MAP2K1,MAPK8,MCTP1,MDFIC,MED1,MEF2C,MFF,MICALL2,MIEF2,MRLN,MTCL1,MTOR,MXI1,MYBPC1,MYBPC3,MYO5A,NBPF3,NDEL1,NEDD4,NF1,NFKBIA,NFKBIE,NKAP,NLGN2,NLGN3,NODAL,NOS1,NOV,NRXN1,NUMA1,NUP214,NUP93,OSCP1,P2RX2,PAK1,PARD3,PCSK9,PDCD5,PDX1,PIK3R2,PIM3,PKD1,PKD2,PLAGL2,PLCG1,PPFIA1,PPM1A,PPM1B,PPP1CC,PPP1R13B,PPP1R9A,PPP2R5A,PPP3CB,PREPL,PRKCD,PSMB7,PTGS2,PTPN14,PTPN23,PTPN6,RAB11A,RAB11FIP2,RAB23,RAB3A,RAB3B,RANGAP1,RAP1A,RHOA,RHOT1,RIMS2,RTN4,RYR2,SAE1,SCFD1,SETD2,SFN,SFRP2,SHH,SIN3A,SLC17A9,SLC30A1,SMAD3,SNX3,SNX33,SPAG5,SPHK1,SPTBN1,SREBF1,SRI,SSH1,STARD7,STK11,STX8,SULF2,SUPT6H,TACR2,TCF7L2,TENM1,TFDP1,TGFB3,THOC2,TLR7,TM9SF4,TMEM30A,TMSB4X,TNNC1,TNNT2,TP73,TPR,TRPC1,UBL4B,UBR5,UNC13B,UNC13D,VIL1,VTI1B,WASHC1,WNK3,WWC1,XPO1,XPO4,YWHAQ,YWHAZ,ZBTB17,ZIC1	MammalFishAncestor	149.342
GO.Biological.Process	GO:0006259	DNA.metabolic.process	94	4.654372e-153	6.012052e-149	6.395800e-151	1.447835e+0	ABRAXAS1,ACTL6A,ALKBH2,ALKBH5,AP5Z1,AQR,ASCC3,ASTE1,ASZ1,ATM,ATRX,BATF,BAZ2A,BCCIP,BRCA2,BRIP1,C14orf39,CCDC36,CCNE1,CCNH,CCNO,CD40LG,CDC7,CDK2AP1,CDT1,CEP164,CHAF1B,CHRNA4,CLSPN,COPS2,COPS4,COPS5,COPS7A,CUL4A,CUL4B,DBF4,DCLRE1A,DDX1,DHX9,DICER1,DNA2,DNAJA3,DNASE1,DNASE1L3,DNASE2B,DNMT1,DNMT3A,DTL,DUT,EHMT1,EHMT2,ENDOG,ENDOV,EP300,EPC2,ERCC2,ERCC6,ETAA1,EYA1,FAAP100,FANCC,FANCI,FOS,FOXL2,FTO,GATAD2A,HELQ,HERC2,HFM1,HIST1H4A,HIST1H4B,HIST1H4C,HIST1H4D,HIST1H4E,HIST1H4F,HIST1H4H,HMGA1,HSP90AA1,HUWE1,ING4,ING5,INO80,INO80D,JMY,KIN,KMT2A,KPNA2,LEF1,MARF1,MBD4,MCMBP,MCMDC2,MEIOB,MEN1,MGMT,MKI67,MLH3,MNAT1,MSH6,MTOR,MUM1,MYBBP1A,MYO18A,NABP2,NAP1L1,NEXMIF,NONO,NPLOC4,NT5E,NTHL1,ORC4,PAPD5,PDS5A,PDS5B,PMS2,POLA1,POLE,POLG,POLK,POLL,POLR2A,POLR2E,POLR2K,PPIA,PPM1D,PRIM1,PRKDC,PSMC3IP,PSMD14,PTGES3,PTMS,RAD54B,RAD9B,RAN,RBBP6,RBMS1,RBX1,RECQL5,REV3L,RFC1,RFC5,RIF1,RNF111,RPA1,RPS27L,RRM2B,RTEL1,RTEL1-TNFRSF6B,SET,SETD2,SFR1,SHPRH,SIN3A,SLC30A9,SLF1,SLF2,SMC1A,SMC3,SMG7,SMUG1,SPHAR,STN1,SUPV3L1,SWAP70,SYCE3,TAOK1,TAOK3,TCF7,TCF7L2,TDRD1,TEN1,TET1,TET2,THAP9,TIPIN,TOP1,TOP2B,TP53BP1,TP73,TRIP12,TRRAP,TWNK,UBA52,UBB,UBE2A,UBE2B,UBE2U,UBR5,UNG,UPF1,USP1,USP43,USP45,USP47,WDR48,XRCC3,XRN2,ZFYVE26,ZSCAN4,ZSWIM7	MammalFishAncestor	148.221
GO.Biological.Process	GO:0099133	ATP.hydrolysis.coupled.anion.transmembrane.transport	95	3.435182e-152	4.437225e-148	4.670763e-150	5.632942e+0	ABCB11,ABCC1,ABCC10,ABCC3,ABCC4,ABCC6,ABCC8,ABCC9,CFTR	MammalFishAncestor	147.353
GO.Biological.Process	GO:0048524	positive.regulation.of.viral.process	96	1.408414e-151	1.819248e-147	1.895050e-149	2.374218e+0	CCNT1,CD4,CNOT7,CTDP1,DDX3X,DHX9,EP300,GTF2B,HACD3,LEF1,MDFIC,MVB12B,NELFB,NELFE,NOTCH1,NR5A2,PABPC1,PDE12,PKN2,POLR2A,POLR2E,POLR2K,PPIA,PPID,SMARCA4,SMC3,TAF11,TFAP4,TMEM250,TMPRSS2,TRIM11,VPS37B	MammalFishAncestor	146.74
GO.Biological.Process	GO:0006352	DNA-templated.transcription,.initiation	97	4.262817e-151	5.506281e-147	5.676578e-149	1.763485e+0	CAVIN1,CCNC,CCNH,CDK8,DACH1,ERCC2,ESR1,ESRRB,ESRRG,GTF2A1L,GTF2A2,GTF2B,GTF3C4,GTF3C5,HIST1H4A,HIST1H4B,HIST1H4C,HIST1H4D,HIST1H4E,HIST1H4F,HIST1H4H,HNF4G,MED1,MED12,MED13,MED14,MED15,MED16,MNAT1,NOTCH1,NPPA,NR1I2,NR2C1,NR2C2AP,NR2E1,NR2E3,NR2F1,NR3C2,NR4A2,NR4A3,NR5A1,NR5A2,NR6A1,POLR1D,POLR2A,POLR2E,POLR2K,POLR3H,PPARG,PPM1D,RARB,RORA,RXRB,SNAPC5,STON1-GTF2A1L,TAF1,TAF11,TAF1B,TAF2,TAF3,TAF4,TAF5,TAF7,TAF7L,TEAD1,THRAP3,UBTF	MammalFishAncestor	146.259
GO.Biological.Process	GO:0072619	interleukin-21.secretion	98	3.417226e-150	4.414031e-146	4.504113e-148	9.545966e+0	FOXP1	MammalFishAncestor	145.355
GO.Biological.Process	GO:0009953	dorsal/ventral.pattern.formation	99	1.115388e-149	1.440747e-145	1.455300e-147	1.954419e+0	DBX1,DLL4,DMRT3,DSCAML1,DYNC2H1,EVX1,FGF8,FKBP8,FOXN4,GLI1,GLI2,GLI3,GSC,GSX2,HHIP,HOXA11,HOXB2,HOXD11,IFT122,LHX1,LHX3,LMX1B,NKX2-1,NKX2-2,NKX6-1,NKX6-2,PAX6,PTCH1,RFX4,SHH,SIX3,SMAD6,SP8,TCTN1,TTC21B,WDR19,WNT7A	MammalFishAncestor	144.841
GO.Biological.Process	GO:0009163	nucleoside.biosynthetic.process	100	5.754614e-149	7.433235e-145	7.433235e-147	2.330649e+0	ACAT1,ADK,ADSS,ADSSL1,AK5,AK9,AMD1,APRT,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP5S,ATP6V0A1,ATP6V0A2,IMPDH2,NME4,NT5E,PAPSS1,PDC,PDCL2,PRPS2,PRTFDC1,SLC25A13,SLC35B2,SLC35B3,STOML2,UCKL1,UMPS,UPP2	MammalFishAncestor	144.129
GO.Biological.Process	GO:0021953	central.nervous.system.neuron.differentiation	101	1.418967e-148	1.832880e-144	1.814732e-146	1.576464e+0	ARX,ATP7A,AXIN1,C12orf57,CHD5,DBX1,DCLK1,DCLK2,DLL4,DLX1,DLX2,DLX5,DMRT3,DYNC2H1,EPHA4,EVX1,FGF8,FOXN4,GDF7,GLI2,GLI3,GSX1,GSX2,HERC1,HOXC10,HOXD10,INHBA,ISL2,KNDC1,LDB1,LEF1,LHX1,LHX3,LHX4,LMO4,MAP2,MNX1,NDEL1,NKX2-1,NKX2-2,NKX6-1,NKX6-2,NR2E1,NR4A2,OGDH,OTP,PAX6,PHOX2A,PHOX2B,POU4F1,PROX1,PTCH1,RAPGEF2,RORA,SALL1,SALL3,SHH,SLC4A10,SPTBN4,SZT2,TBR1,TCTN1,UNCX,UQCRQ,WNT2,WNT7A,ZEB2	MammalFishAncestor	143.737
GO.Biological.Process	GO:0035926	chemokine.(C-C.motif).ligand.2.secretion	102	3.373584e-148	4.357658e-144	4.272214e-146	8.228260e+0	F2RL1,FOXP1,MCOLN2	MammalFishAncestor	143.361
GO.Biological.Process	GO:0008542	visual.learning	103	2.067165e-147	2.670157e-143	2.592385e-145	2.631699e+0	ABCC8,ATP1A2,DRD3,FOXB1,HMGCR,HRH1,KIT,KMT2A,MEIS2,MTOR,NF1,NLGN3,NPS,PIAS1,PPP1R1B,TANC1	MammalFishAncestor	142.573
GO.Biological.Process	GO:0010001	glial.cell.differentiation	104	9.297629e-147	1.200975e-142	1.154783e-144	1.740427e+0	ADAM22,AKT1,ARHGEF10,BOK,CNP,CNTNAP1,DAG1,DICER1,DNER,EIF2B2,ERBB3,ERCC2,FGF5,GCM1,GLI3,GPR157,HDAC10,HDAC11,LAMA2,LAMB2,LEF1,LRP1,MAP2K1,MED12,METTL14,MPP5,MT3,MYOC,NAB1,NF1,NKX2-1,NKX2-2,NKX6-1,NKX6-2,NLGN3,NOTCH1,PARD3,PAX2,PAX6,PHOX2B,POU3F1,POU3F2,PRDM8,PTPRZ1,RELN,ROR1,SHH,SOX2,SOX6,STAT3,TENM4,TRPC4,WASF3	MammalFishAncestor	141.92
GO.Biological.Process	GO:0030198	extracellular.matrix.organization	105	8.766975e-146	1.132430e-141	1.078505e-143	1.594130e+0	ADAM10,ADAM12,ADAMTS14,ADAMTS9,ADAMTSL4,AGRN,ANXA2,ATP7A,CAPNS2,COL11A1,COL11A2,COL12A1,COL19A1,COL1A1,COL1A2,COL2A1,COL4A1,COL4A2,COL7A1,COL9A1,COMP,CTSK,CTSS,DAG1,DNAJB6,EGFL6,ELANE,ERCC2,ERO1B,EXOC8,FBLN2,FBN1,FBN2,FGA,FGB,FGG,FN1,GAS6,GPM6B,HSPG2,ICAM1,ICAM3,ICAM4,ICAM5,ITGA6,ITGB4,ITGB6,KDR,LAMA2,LAMA3,LAMA4,LAMB1,LAMB2,LAMC1,LAMC2,MATN1,MATN3,MMP2,MYF5,MYH11,MYO1E,NCAN,NF1,NFKB2,NID1,NOX1,NOXO1,NPNT,NR2E1,OLFML2A,P3H4,PDGFRA,POMT1,POSTN,PXDN,SCUBE3,SERPINF2,SFRP2,SH3PXD2A,SPARC,SULF1,SULF2,TLL1,VIT,WASHC1,WT1	MammalFishAncestor	140.946
GO.Biological.Process	GO:0043062	extracellular.structure.organization	106	9.541240e-146	1.232442e-141	1.162681e-143	1.594026e+0	ADAM10,ADAM12,ADAMTS14,ADAMTS9,ADAMTSL4,AGRN,ANXA2,ATP7A,CAPNS2,COL11A1,COL11A2,COL12A1,COL19A1,COL1A1,COL1A2,COL2A1,COL4A1,COL4A2,COL7A1,COL9A1,COMP,CTSK,CTSS,DAG1,DNAJB6,EGFL6,ELANE,ERCC2,ERO1B,EXOC8,FBLN2,FBN1,FBN2,FGA,FGB,FGG,FN1,GAS6,GPM6B,HSPG2,ICAM1,ICAM3,ICAM4,ICAM5,ITGA6,ITGB4,ITGB6,KDR,LAMA2,LAMA3,LAMA4,LAMB1,LAMB2,LAMC1,LAMC2,MATN1,MATN3,MMP2,MYF5,MYH11,MYO1E,NCAN,NF1,NFKB2,NID1,NOX1,NOXO1,NPNT,NR2E1,OLFML2A,P3H4,PDGFRA,POMT1,POSTN,PXDN,SCUBE3,SERPINF2,SFRP2,SH3PXD2A,SPARC,SULF1,SULF2,TLL1,VIT,WASHC1,WT1	MammalFishAncestor	140.909
GO.Biological.Process	GO:0035239	tube.morphogenesis	107	1.324331e-145	1.710638e-141	1.598727e-143	1.454055e+0	ACVR1,ADAMTS16,ADM,ARID1A,BBS5,BCAS3,BTRC,CC2D2A,CCDC39,CLIC4,COL4A1,CTHRC1,CTNNBIP1,DAG1,DLG5,DLL4,DVL2,EDAR,EDNRA,EPHA4,ESR1,EYA1,FAT4,FGF8,FOLR1,FOXD1,FOXN4,FZD6,GATA3,GATA6,GDF7,GLI1,GLI2,GLI3,GLMN,HHIP,HNF1B,HOXA1,HOXA11,HOXA5,HOXD11,HOXD13,ID2,IFT122,IRX1,IRX2,IRX3,ITGB1BP1,KAT2A,KDM2B,KDM5B,LEF1,LHX1,LIAS,LMO4,LRP2,MED1,MED12,MEF2C,MEGF8,MET,MIB1,MICAL2,MKKS,MYCN,NIPBL,NKX2-1,NODAL,NOTCH1,NPHP3,NPNT,NR4A3,NRARP,NTN1,PAK1,PAX2,PDGFRA,PGF,PHB2,PITX2,PKD1,PKD2,PLXNB2,PLXND1,PRKACB,PRKD2,PTCH1,RBM15,RHOA,RHOB,RYR2,SALL1,SALL4,SDCCAG8,SETD2,SFRP2,SHH,SHOX2,SIX1,SIX2,SMAD3,SOX18,STARD13,STK3,TBX1,TBX2,TCF7,TCTN1,TSC1,TSC2,WT1,ZEB1,ZEB2	MammalFishAncestor	140.767
GO.Biological.Process	GO:0043010	camera-type.eye.development	108	1.660649e-145	2.145060e-141	1.986167e-143	1.503083e+0	ACTL6A,ALDH1A2,ALDH1A3,ARID1A,C12orf57,CACNA1C,CC2D2A,CLCN2,CLIC4,COL4A1,CRYBA1,CRYGA,CRYGB,CRYGD,FBN1,FBN2,FKBP8,FOXL2,FOXN4,FOXP2,GATA3,GJA8,GLI3,GNAT1,GNAT2,GNB1,GPD2,IFT122,IMPDH2,INHBA,IRX5,JAG1,KDM2B,KDM5B,LAMB2,LHX1,LPCAT1,MAB21L1,MAB21L2,MED1,MEGF11,MEIS1,MFN2,MIP,MYF5,MYOM1,MYOM2,NF1,NR2E1,NR2E3,OSR2,PAPD4,PAX2,PAX6,PDE6C,PDGFRA,PITX2,PITX3,POU4F2,PROX1,PROX2,RAB11FIP4,RARB,RBP4,RCN1,RHO,RPGRIP1L,RS1,SDHAF4,SDK1,SDK2,SERPINF1,SHH,SIX3,SMAD3,SMARCA4,SMARCD3,SP3,TBX2,TENM3,TFAP2A,TTLL5,TUB,TWSG1,VAX1,WDPCP,WDR19,WNT2,WNT2B,WNT5B,WNT7A,WT1,XRN2,ZEB1	MammalFishAncestor	140.669
GO.Biological.Process	GO:0060562	epithelial.tube.morphogenesis	109	3.392126e-145	4.381609e-141	4.019825e-143	1.487221e+0	ACVR1,ADAMTS16,ADM,ARID1A,BBS5,BTRC,CC2D2A,CCDC39,CLIC4,COL4A1,CTHRC1,CTNNBIP1,DAG1,DLG5,DLL4,DVL2,EDNRA,EPHA4,ESR1,EYA1,FAT4,FGF8,FOLR1,FOXD1,FOXN4,FZD6,GATA3,GDF7,GLI2,GLI3,GLMN,HHIP,HNF1B,HOXA11,HOXA5,HOXD11,IFT122,IRX1,IRX2,IRX3,KAT2A,KDM2B,KDM5B,LEF1,LHX1,LIAS,LMO4,LRP2,MED1,MED12,MEF2C,MEGF8,MET,MIB1,MICAL2,MKKS,MYCN,NKX2-1,NODAL,NOTCH1,NPHP3,NPNT,NRARP,NTN1,PAK1,PAX2,PGF,PHB2,PITX2,PKD1,PKD2,PLXNB2,PLXND1,PRKACB,PRKD2,PTCH1,RBM15,RHOA,RHOB,RYR2,SALL1,SALL4,SETD2,SFRP2,SHH,SIX1,SMAD3,SOX18,STARD13,STK3,TBX2,TCTN1,TSC1,TSC2,WT1,ZEB2	MammalFishAncestor	140.358
GO.Biological.Process	GO:0002520	immune.system.development	110	6.099918e-145	7.879264e-141	7.162967e-143	1.405321e+0	ABI1,ACOD1,ADAM17,ANXA2,ARIH2,ASXL1,ATM,ATP11C,ATP7A,BATF,BRCA2,C12orf29,CACNA1C,CBFA2T3,CCNB2,CD248,CD4,CD40LG,CDH17,CEBPD,CRKL,CSF2,CUL4A,CXCR5,CYLD,DCSTAMP,DLL4,DNAJA3,EFNA2,EIF2AK1,EP300,ERCC2,EVI2B,F2RL1,FARP2,FLT3,FNIP1,FOXP1,FZD8,GAB2,GAS6,GATA3,GFI1,GLI3,HERC6,HOXA3,HOXB3,HOXB4,HOXB7,HYAL2,IL3,INHA,INHBA,JAG1,KCNAB2,KDR,KIT,KITLG,KMT2A,LEF1,LEPR,LMO4,LRRC8A,LRRK1,MAD1L1,MAP2K1,MECOM,MED1,MEF2C,MEIS1,MLF1,MMP21,MSH6,MT1G,MYO1E,NFE2L1,NFKB2,NKAP,ONECUT1,OSTM1,PAPD4,PAX1,PDGFRA,PGM3,PIK3CD,PITX2,PLCL2,PMS2,POLL,PPARG,PPP2R3C,PPP3CB,PREX1,PRKDC,PRRC2C,PRTN3,PTPN2,PTPN6,PTPRZ1,PYGO1,RAF1,RASGRP4,RBM15,RBM47,RHOH,RORA,RRS1,RUNX3,SART3,SATB1,SBNO2,SFRP2,SH3PXD2A,SHH,SIN3A,SIX1,SIX4,SLC11A2,SMAD3,SOX6,SP3,SPNS2,SPTA1,STAT3,STAT5B,STK11,STK3,SWAP70,TAZ,TBX1,TBX21,TCF7,TCTA,TET2,TGFBR3,TNFRSF11A,TNFSF11,TPO,TSC1,TUSC2,TWSG1,TYRO3,UNG,VPS33A,WDR7,WNT2B,ZBTB24,ZFP36L2	MammalFishAncestor	140.104
GO.Biological.Process	GO:0043367	CD4-positive,.alpha-beta.T.cell.differentiation	111	1.206222e-144	1.558077e-140	1.403673e-142	2.925393e+0	ATP7A,BATF,FOXP1,GATA3,LEF1,PAX1,RORA,SATB1,STAT3	MammalFishAncestor	139.807
GO.Biological.Process	GO:0046390	ribose.phosphate.biosynthetic.process	112	3.608620e-144	4.661254e-140	4.161834e-142	2.097971e+0	ACAT1,ADCY5,ADCY6,ADCY7,ADCY9,ADK,ADM,ADSS,ADSSL1,AK5,AK9,AMPD2,AMPD3,APRT,ATIC,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP5S,ATP6V0A1,ATP6V0A2,IMPDH2,NME4,NPPA,NPPB,PAICS,PAPSS1,PPAT,PRPS2,PYGL,RFK,SLC25A13,SLC35B2,SLC35B3,STOML2,UCKL1,UCN2,UMPS,UPP2	MammalFishAncestor	139.331
GO.Biological.Process	GO:1901659	glycosyl.compound.biosynthetic.process	113	4.686708e-144	6.053821e-140	5.357363e-142	2.293005e+0	ACAT1,ADK,ADSS,ADSSL1,AK5,AK9,AMD1,APRT,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP5S,ATP6V0A1,ATP6V0A2,IMPDH2,NME4,NT5E,PAPSS1,PDC,PDCL2,PRPS2,PRTFDC1,SLC25A13,SLC35B2,SLC35B3,STOML2,UCKL1,UMPS,UPP2	MammalFishAncestor	139.218
GO.Biological.Process	GO:0051651	maintenance.of.location.in.cell	114	3.620726e-143	4.676892e-139	4.102537e-141	2.332178e+0	AKAP9,AKT1,ANK3,ARHGAP21,CCDC22,CD4,DAG1,DZIP1,FLNA,FLNB,GPSM2,HK1,JUP,KEAP1,MORC3,MXI1,NFKBIA,NFKBIE,NR5A1,PDIA2,PKD1,PKD2,POLR2M,SHANK1,SKP1,SPAG4,SPTBN4,SRGN,SRI,SYNE1,SYNE3,TAF3,TLN2,TMSB4X	MammalFishAncestor	138.33
GO.Biological.Process	GO:0030316	osteoclast.differentiation	115	4.204365e-143	5.430778e-139	4.722416e-141	2.907738e+0	ANXA2,DCSTAMP,EFNA2,FARP2,FOXP1,GAB2,LRRK1,OSTM1,SBNO2,SH3PXD2A,TCTA,TNFRSF11A,TNFSF11	MammalFishAncestor	138.265
GO.Biological.Process	GO:0046825	regulation.of.protein.export.from.nucleus	116	5.286205e-143	6.828191e-139	5.886372e-141	3.262467e+0	BAG3,EMD,GAS6,GSK3B,PPM1A,PTPN14,RANGAP1,SFN,TCF7L2,TPR,XPO1,XPO4	MammalFishAncestor	138.166
GO.Biological.Process	GO:0043087	regulation.of.GTPase.activity	117	2.058317e-142	2.658728e-138	2.272417e-140	1.429210e+0	ACAP1,ADGRB3,ADPRHL1,ADRB1,AGAP5,AGFG1,AGRN,ARFGAP1,ARFGEF1,ARHGAP10,ARHGAP12,ARHGAP15,ARHGAP18,ARHGAP19,ARHGAP21,ARHGAP22,ARHGAP24,ARHGAP29,ARHGAP45,ARHGAP9,ARHGDIG,ARHGEF10,ARHGEF16,ARHGEF38,ARHGEF6,ASAP2,AXIN1,BCAS3,BNIP2,CCL20,CCPG1,CDC42EP4,CDKL5,CHN1,CORO1C,CPEB2,DENND1B,DEPDC7,DOCK1,DOCK4,DOCK7,DOCK8,DOCK9,DVL2,EIF2S1,EPHA4,EVI5,F2R,F2RL1,FAM13A,FGD6,FICD,FZD10,GAPVD1,GIT1,GIT2,GNAO1,GNB5,GPS2,GPSM1,GRTP1,GSK3B,HACD3,ICAM1,IQGAP2,IQSEC1,ITGA6,ITGB1BP1,KALRN,LARS,LIMS1,LLGL1,LLGL2,MET,MKKS,MTOR,MYO9A,NDEL1,NF1,NPRL2,PGAM5,PIK3R2,PKP4,PLXNB2,PLXNB3,PLXND1,PREX1,PREX2,PRTN3,PTPRN2,RABGAP1,RALBP1,RALGAPA1,RALGAPA2,RANBP1,RANBP2,RANGAP1,RAP1A,RAP1GAP,RAPGEF2,RAPGEF6,RASA1,RASA3,RASGEF1B,RASGRP2,RASGRP3,RGS11,RGS12,RGS22,RHOH,RIC8B,RIN1,RSU1,SBF1,SBF2,SIPA1L1,STARD13,STMN3,STXBP5,TBC1D13,TBC1D14,TBC1D4,TBC1D5,TBCK,TIAM2,TSC1,TSC2	MammalFishAncestor	137.575
GO.Biological.Process	GO:0042762	regulation.of.sulfur.metabolic.process	118	4.843376e-142	6.256189e-138	5.301855e-140	3.315273e+0	BHMT,COMT,DLD,NFE2L2,PDK1,PDK2,PDK3,PDK4,PDP1,TCF7L2	MammalFishAncestor	137.204
GO.Biological.Process	GO:1900424	regulation.of.defense.response.to.bacterium	119	3.019523e-140	3.900318e-136	3.277578e-138	5.893758e+0	ARG2,F2RL1,FOXP1,MAPKBP1,UNC13B	MammalFishAncestor	135.409
GO.Biological.Process	GO:0009260	ribonucleotide.biosynthetic.process	120	1.144942e-139	1.478922e-135	1.232435e-137	2.094718e+0	ACAT1,ADCY5,ADCY6,ADCY7,ADCY9,ADK,ADM,ADSS,ADSSL1,AK5,AK9,AMPD2,AMPD3,APRT,ATIC,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP5S,ATP6V0A1,ATP6V0A2,IMPDH2,NME4,NPPA,NPPB,PAICS,PAPSS1,PPAT,PRPS2,RFK,SLC25A13,SLC35B2,SLC35B3,STOML2,UCKL1,UCN2,UMPS,UPP2	MammalFishAncestor	134.83
GO.Biological.Process	GO:0032386	regulation.of.intracellular.transport	121	1.190667e-139	1.537985e-135	1.271062e-137	1.454762e+0	ACTL6A,ADORA2B,ANK3,ANXA2,ARIH2,ARV1,ATP2A2,BAG3,BAMBI,BAP1,BCAP31,BCAS3,BMP6,CCDC22,CEP131,CEP290,CNIH2,CTSK,CYFIP1,CYLD,DACT3,DHX9,DNAJC13,DPH6,DYNC1H1,EDAR,EDEM1,EFCAB7,EMD,ERLEC1,F2R,FGF14,FLNA,FYN,GAB2,GAS6,GCC2,GLI3,GLS2,GPR26,GSK3B,HUWE1,HYAL2,ICE1,INSIG1,ITGB1BP1,JUP,KANK1,KAT2A,KEAP1,KIF5B,LAMP1,LDLRAP1,LRRC46,MAP2K1,MDFIC,MED1,MFF,MICALL2,MIEF2,MRLN,MTCL1,MTOR,MXI1,MYBPC1,MYBPC3,NBPF3,NDEL1,NEDD4,NF1,NFKBIA,NFKBIE,NKAP,NODAL,NOV,NUMA1,NUP214,NUP93,OSCP1,PAK1,PCSK9,PDCD5,PIK3R2,PKD1,PKD2,PLAGL2,PPM1A,PPM1B,PPP1CC,PREPL,PRKCD,PSMB7,PTGS2,PTPN14,PTPN23,RAB23,RAB3A,RANGAP1,RAP1A,RHOA,RHOT1,RIMS2,SAE1,SCFD1,SETD2,SFN,SFRP2,SHH,SLC17A9,SMAD3,SNX3,SPAG5,SPHK1,SREBF1,SRI,STARD7,SULF2,SUPT6H,TCF7L2,TENM1,TGFB3,THOC2,TLR7,TM9SF4,TMEM30A,TMSB4X,TNNC1,TNNT2,TPR,UBL4B,UBR5,UNC13B,UNC13D,WWC1,XPO1,XPO4,ZBTB17,ZIC1	MammalFishAncestor	134.813
GO.Biological.Process	GO:0035195	gene.silencing.by.miRNA	122	1.995703e-139	2.577850e-135	2.112991e-137	3.161100e+0	AGO1,AGO3,AGO4,CNOT7,DGCR8,DICER1,PRKRA,PUM1,PUM2,RAN,SMAD1,SMAD3,STAT3,TNRC6A,ZC3H7B	MammalFishAncestor	134.589
GO.Biological.Process	GO:2000574	regulation.of.microtubule.motor.activity	123	2.030006e-139	2.622159e-135	2.131836e-137	5.682335e+0	DYNC1I1,DYNC1I2,MTCL1,NDE1,NDEL1	MammalFishAncestor	134.581
GO.Biological.Process	GO:0048729	tissue.morphogenesis	124	2.274064e-139	2.937408e-135	2.368878e-137	1.362603e+0	ACTA1,ACTC1,ACVR1,ADAM17,ADAMTS16,ADM,ALDH1A2,ALDH1A3,ARHGAP12,ARID1A,ATP7A,AXIN1,BBS5,BTRC,C5orf42,CC2D2A,CCDC39,CEP290,CLIC4,COL11A1,COL4A1,CTHRC1,CTNNBIP1,CYP7B1,DAG1,DLG5,DLL4,DVL2,EDNRA,EPHA4,ESR1,EYA1,FAT4,FGF8,FLNA,FOLR1,FOXD1,FOXN4,FRAS1,FREM2,FZD6,GATA3,GCM1,GCNT1,GCNT3,GDF7,GLI2,GLI3,GLMN,GPI,HHIP,HNF1B,HOXA11,HOXA5,HOXB13,HOXB2,HOXB4,HOXD11,HOXD13,IFT122,INHBA,IRX1,IRX2,IRX3,ITGB4,JAG1,KAT2A,KDM2B,KDM5B,KDM6B,LEF1,LHX1,LIAS,LMO4,LRP2,MATN1,MED1,MED12,MEF2C,MEGF8,MET,MIB1,MICAL2,MKKS,MPP5,MYBPC3,MYCN,MYF5,MYF6,MYL2,MYO9A,NKX2-1,NODAL,NOTCH1,NPHP3,NPNT,NR4A3,NRARP,NTN1,PAK1,PAX2,PDX1,PGF,PHB2,PITX2,PKD1,PKD2,PLXNB2,PLXND1,POU4F1,PRKACB,PRKD2,PROX1,PTCH1,RAB10,RBM15,RHOA,RHOB,RIPK4,RPGRIP1L,RYR2,SALL1,SALL4,SETD2,SFRP2,SHH,SHOX2,SIX1,SIX2,SIX3,SMAD1,SMAD3,SOX18,STARD13,STK3,TBX1,TBX2,TBX4,TCAP,TCTN1,TFAP2A,TGFBR3,TNNC1,TNNI1,TNNT2,TPM1,TSC1,TSC2,TWSG1,UBE4B,VCL,WNT2,WNT7A,WT1,XIRP2,ZEB2,ZFPM2	MammalFishAncestor	134.532
GO.Biological.Process	GO:1902895	positive.regulation.of.pri-miRNA.transcription.from.RNA.polymerase.II.promoter	125	3.607768e-139	4.660154e-135	3.728123e-137	3.884437e+0	FOS,SMAD1,SMAD3,SMAD6,SMARCA4,STAT3,TEAD1	MammalFishAncestor	134.332
GO.Biological.Process	GO:0051056	regulation.of.small.GTPase.mediated.signal.transduction	126	5.958264e-139	7.696290e-135	6.108166e-137	1.531129e+0	ABCA1,ARFGEF1,ARFGEF2,ARHGAP10,ARHGAP12,ARHGAP15,ARHGAP18,ARHGAP19,ARHGAP21,ARHGAP22,ARHGAP24,ARHGAP29,ARHGAP45,ARHGAP9,ARHGDIG,ARHGEF10,ARHGEF16,ARHGEF26,ARHGEF28,ARHGEF38,ARHGEF6,AUTS2,CGNL1,CHN1,CYTH3,DENND4B,DEPDC7,F2R,F2RL1,F2RL2,FAM13A,FARP2,FGD6,GBF1,IQSEC1,IQSEC2,KALRN,KANK1,KIF14,KITLG,MADD,MAPKAP1,MCF2,MET,MFN2,MMD2,MYO9A,MYOC,NF1,NOTCH1,OBSCN,OGT,PIK3R2,PLCE1,PREX1,PREX2,RAF1,RALBP1,RALGAPA1,RALGAPA2,RALGPS1,RAP1GAP,RASA1,RASA3,RASGRP4,RELN,RHOA,RHOB,RHOF,RHOH,RHOT1,RHOT2,SCAI,SHOC2,SIPA1L1,SOS2,SSX2IP,STARD13,STMN3,TIAM2,TNK1,TRIM67,TRIO,TSC2	MammalFishAncestor	134.114
GO.Biological.Process	GO:0009956	radial.pattern.formation	127	6.752050e-139	8.721623e-135	6.867420e-137	7.910744e+0	NR2F2	MammalFishAncestor	134.059
GO.Biological.Process	GO:0009743	response.to.carbohydrate	128	1.715519e-138	2.215936e-134	1.731200e-136	1.851261e+0	ACVR1C,APOB,ATG7,CDT1,EIF2B2,ENDOG,ENSA,FKBP1B,FOXO3,GAS6,GCLC,GCLM,GJB6,HNF1B,ICAM1,IRS2,KCNJ11,MEN1,NKX2-2,NKX6-1,P2RX2,PAX2,PDK3,PDX1,POLG,PRKCB,PTGS2,PTPRN,PTPRN2,RAB11FIP2,RAF1,RAP1A,RPS6KB1,SELENOS,SERPINF1,SIN3A,SLC26A6,SLC2A5,SLC6A1,SPARC,SREBF1,TCF7L2,TWNK,UNC13B,ZNF236	MammalFishAncestor	133.654
GO.Biological.Process	GO:0030901	midbrain.development	129	6.715542e-138	8.674466e-134	6.724392e-136	2.120850e+0	ACTB,BARHL1,CNP,DLG5,EN2,FOXB1,FZD6,GDF7,GNB4,INA,KAT2A,KDM2B,MAPKAP1,MBP,NR4A2,OTX1,OTX2,PHOX2A,PITX3,RFX4,RHOA,SEC16A,SHH,SMAD1,SMAD9,SUDS3,SYPL2,TAF1,TTBK1,UQCRQ,WNT2,YWHAQ	MammalFishAncestor	133.062
GO.Biological.Process	GO:0032784	regulation.of.DNA-templated.transcription,.elongation	130	9.383736e-138	1.212097e-133	9.323824e-136	3.512113e+0	AXIN1,CTR9,ELL,ERCC6,HTATSF1,LDB1,NELFB,NELFE,POU4F1,RECQL5,SHH,SUPT6H,ZMYND11,ZNF326	MammalFishAncestor	132.916
GO.Biological.Process	GO:0043069	negative.regulation.of.programmed.cell.death	131	1.151521e-137	1.487420e-133	1.135435e-135	1.328446e+0	AATF,ACTC1,ACVR1,AGO4,AKT1,AMBRA1,ANKLE2,AREL1,ARF4,ARG2,ARHGAP10,AVEN,AZU1,BAG3,BAG5,BARHL1,BCL2L10,BIRC6,BIRC7,BNIP2,BOK,C5AR1,CAPN3,CD40LG,CLDN7,COL2A1,COMP,COPS5,CRLF1,CSF2,CTTN,DDX3X,DHCR24,DLX1,DNAJA3,DNAJB6,DNAJC3,DNAJC5,DOCK8,EDNRB,EIF5A,EN2,ENO1,ERBB3,ERC1,EVI2B,EYA1,F2R,FAIM,FANK1,FASLG,FFAR4,FGA,FGB,FGF20,FGF8,FGG,FKBP8,FLNA,FNIP1,FOXB1,FOXP1,FYN,GABRB2,GAS6,GATA3,GATA6,GCG,GCLC,GCLM,GLI2,GLI3,GPI,GPX1,GSK3B,HCK,HHIP,HIP1R,HIPK3,HMGCR,HNF1B,HTATIP2,HTT,ICAM1,IRS2,ITGA6,IVNS1ABP,KANK2,KDM2B,KDR,KIF14,KIT,KITLG,KRT18,LAMTOR5,LEF1,LHX3,LHX4,LRP1,MAP2K5,MAPK8,MCL1,MDK,MECOM,MED1,MEF2C,MEIS3,MET,MGMT,MNAT1,MT3,MTOR,MYD88,MYO18A,NAA38,NDUFA13,NFE2L2,NFKBIA,NOD2,NONO,NOTCH1,NR2E1,NR4A2,NR4A3,OXR1,PA2G4,PAK5,PAX2,PDCD4,PDK4,PDX1,PHB2,PIAS1,PIM3,PLAC8,POU3F3,POU4F1,PRKCA,PRKCD,PRKCQ,PRKCZ,PRKDC,PROK2,PSMG2,PTGFR,PTGS2,PTRH2,QARS,RAF1,RARB,RASA1,RB1CC1,RNF34,ROCK1,RPL10,RPS3A,RPS6KB1,RRM2B,SELENOS,SET,SFN,SFRP2,SH3RF1,SHH,SIN3A,SIX1,SIX4,SLC25A4,SLC39A10,SMAD3,SMAD6,SPHK1,STAT3,STAT5B,STK40,SUPV3L1,TAX1BP1,TBX1,TCF7,TCF7L2,TFAP2A,TGFB3,TIAF1,TMEM161A,TMF1,TNFAIP8,TNFRSF6B,TOX3,TP73,TRAP1,TXNDC12,TXNDC5,TYRO3,UBA52,UBB,UBE2B,UCN,UFM1,UNG,URI1,USP47,VDAC2,VIL1,WNK3,WNT7A,WT1,YWHAZ,ZMYND11,ZNF304	MammalFishAncestor	132.828
GO.Biological.Process	GO:0035710	CD4-positive,.alpha-beta.T.cell.activation	132	1.440842e-137	1.861136e-133	1.409951e-135	2.829721e+0	ATP7A,BATF,FOXP1,GATA3,LEF1,PAX1,RORA,SATB1,STAT3,STOML2	MammalFishAncestor	132.73
GO.Biological.Process	GO:0014070	response.to.organic.cyclic.compound	133	2.888638e-136	3.731254e-132	2.805454e-134	1.308463e+0	AANAT,ABCA1,ABCB4,ABCC4,ACACB,ACAT1,ACOD1,ACR,ACSL1,ACSL3,ACTA1,ADCY5,ADCY6,ADM,ADSS,AGO1,AGO3,AGO4,AKAP6,AKAP9,AKT1,ALDH1A2,ALPL,ANXA3,APOB,AQP9,ARID1A,ATF1,ATG7,ATP1A2,BMP6,BTRC,CARD9,CASP7,CATSPER3,CCDC62,CCNE1,CD4,CFTR,CHRNA1,CHRNA4,CHRNB1,COL1A1,COMT,CRH,DAG1,DDX1,DGCR8,DHH,DHX36,DHX9,DIAPH1,DICER1,DNMT3A,DRD3,EDNRB,ENDOG,ESR1,ESRRB,ESRRG,FECH,FGF8,FKBP1B,FKBP4,FLT3,FOLR1,FOLR2,FOS,FOXO3,FOXP2,GABRA1,GABRB2,GABRG2,GCLC,GCLM,GJB2,GLI2,GNAO1,GNB1,GPI,HNF1B,HNF4G,HNRNPD,HOMER1,HOMER2,HOXB13,HOXD13,HRH1,HTR5A,ICAM1,IDH1,IFIH1,IMPACT,INHBA,ITGA6,ITPR2,JUND,JUP,KALRN,KAT2A,KCNJ11,KCNJ8,KIF1B,KLF5,LEF1,MBD4,MDK,MED1,MED12,MED13,MED14,MED16,MEF2C,MGMT,MKI67,MSR1,MTHFR,MTOR,NEDD4,NFKBIA,NKX2-2,NKX6-1,NOD2,NOTCH1,NPPB,NR1I2,NR2C1,NR2E1,NR2E3,NR2F1,NR2F2,NR3C2,NR4A2,NR4A3,NR5A1,NR5A2,NR6A1,OSBPL7,P2RX1,P2RX2,P2RY11,P2RY12,P2RY13,PAQR5,PAQR9,PDE12,PDX1,PELI1,PIAS1,PITX3,PKD2,PLA2G4F,PLPP1,POSTN,POU4F1,POU4F2,PPARG,PPP1R1B,PPP1R9B,PRKACB,PRKRA,PSMB2,PTCH1,PTGFR,PTGS2,PTPRN,PUM1,PUM2,RAN,RAP1A,RAPGEF2,RARB,RECQL5,RHOXF1,RORA,RPL32,RPS6KB1,RXRB,RYR1,RYR2,RYR3,SDC1,SDK1,SERPINF1,SIN3A,SIX1,SLC26A5,SLC26A6,SLC6A1,SLC6A3,SMAD1,SMAD3,SMAD9,SP5,SPARC,SREBF1,SSH1,STAT1,STAT3,STAT5B,STRN3,TAF1,TAF2,TAF7,TET2,TFAP4,TGFB3,THRAP3,TMF1,TP53I13,UBR5,UCN,URI1,WBP2,WNT7A,WT1,ZC3H7B,ZFP36L2	MammalFishAncestor	131.428
GO.Biological.Process	GO:0072070	loop.of.Henle.development	134	8.668034e-136	1.119650e-131	8.355597e-134	3.353198e+0	IRX1,IRX2,IRX3,JAG1,PKD1,PKD2,POU3F3	MammalFishAncestor	130.951
GO.Biological.Process	GO:0061326	renal.tubule.development	135	9.048327e-136	1.168772e-131	8.657573e-134	1.822375e+0	ACAT1,ADAMTS16,COL4A1,CTNNBIP1,EYA1,FAT4,FGF8,FOXD1,GATA3,GLI3,HNF1B,HOXA11,HOXD11,IRX1,IRX2,IRX3,JAG1,LHX1,MEF2C,NOTCH1,NPNT,PAX2,PGF,PKD1,PKD2,POU3F3,PTCH1,SALL1,SHH,SIX1,STAT1,WT1	MammalFishAncestor	130.932
GO.Biological.Process	GO:0021520	spinal.cord.motor.neuron.cell.fate.specification	136	3.455353e-135	4.463279e-131	3.281823e-133	3.346314e+0	GLI2,GLI3,HOXC10,HOXD10,ISL2,LHX3,MNX1,NKX6-1,NKX6-2,PAX6	MammalFishAncestor	130.35
GO.Biological.Process	GO:0090316	positive.regulation.of.intracellular.protein.transport	137	2.937023e-134	3.793753e-130	2.769162e-132	1.634134e+0	ACTL6A,ANK3,ARIH2,BAG3,BAMBI,BAP1,BCAP31,BCAS3,BMP6,CEP131,CEP290,CTSK,DPH6,EDAR,EDEM1,EFCAB7,EMD,F2R,FLNA,FYN,GAS6,GLI3,GLS2,GPR26,GSK3B,HUWE1,HYAL2,ICE1,ITGB1BP1,JUP,KANK1,KAT2A,KIF5B,LRRC46,MED1,MFF,MICALL2,MIEF2,MTCL1,MYBPC1,NBPF3,NKAP,NODAL,NUP93,OSCP1,PAK1,PDCD5,PIK3R2,PLAGL2,PPM1A,PRKCD,PSMB7,PTGS2,RHOA,SAE1,SFN,SFRP2,SHH,SLC17A9,SMAD3,SPHK1,STARD7,SULF2,TCF7L2,TENM1,TGFB3,TLR7,TM9SF4,TMEM30A,TPR,UBL4B,UBR5,XPO4,ZBTB17,ZIC1	MammalFishAncestor	129.421
GO.Biological.Process	GO:0009057	macromolecule.catabolic.process	138	3.607584e-134	4.659916e-130	3.376751e-132	1.354712e+0	ACR,ADAMTS9,AFG1L,AGO1,AGO3,AGO4,AGRN,AKT1,AMFR,ANAPC10,ANAPC15,ANAPC7,ANXA2,APOB,AREL1,ARIH2,ARRDC1,ARSB,ASB2,ATM,ATXN3L,AXIN1,BAP1,BTBD1,BTRC,BUB1B,BUB3,C18orf25,CELA1,CHFR,CLN5,CLN8,CLOCK,CLTC,CNOT7,CNOT9,CSPG4,CSPG5,CTBS,CTSK,CTSS,CUL2,CUL4A,CUL4B,CUL9,CYLD,DCP1A,DCP1B,DDIT3,DDX6,DERL1,DHX34,DICER1,DIS3,DIS3L,DNA2,DNAJB9,DNAJC3,DNASE1,DNASE1L3,DNASE2B,DTL,EDEM1,EIF4B,EIF4G1,ELANE,ENC1,ENDOG,ENPEP,ENSG00000256206,ENSG00000272772,ERLEC1,EXOSC10,EXOSC8,FAP,FBXL14,FBXL18,FBXL22,FBXL3,FBXL4,FBXL5,FBXO11,FBXO21,FBXO9,FBXW4,FOXL2,GALNS,GSK3B,HERC2,HEXB,HNRNPD,HPSE,HSPG2,HUWE1,HYAL1,HYAL2,HYAL3,HYAL4,IDE,KCTD10,KEAP1,KIF14,KLHL11,KLHL2,KLHL29,KLHL31,LAMP2,LDLR,LNX1,LSM4,LSM6,LYVE1,METTL14,MGEA5,MTOR,MVB12B,NAGLU,NBAS,NCAN,NEDD4,NFE2L2,NGLY1,NPLOC4,NT5C3B,PABPC1,PABPC4,PAN3,PAPD4,PAPD5,PCSK9,PDE12,PFKM,PGM1,PHKA2,PHKB,PIK3R4,POMT1,POP1,PPP2CA,PSMA1,PSMA5,PSMA6,PSMA7,PSMB2,PSMB7,PSMB8,PSMB9,PSMD11,PSMD12,PSMD14,PSMD2,PSMD6,PTPN23,PYGL,PYGM,RAB12,RANBP1,RANBP2,RBBP6,RBX1,RLIM,RNF111,RNF165,RNF19A,RNF213,RNF216,RNF34,RNF41,RNF6,RPL10,RPL19,RPL21,RPL22,RPL27A,RPL30,RPL32,RPL35,RPL39,RPL4,RPL41,RPL5,RPL9,RPLP1,RPS10,RPS15,RPS2,RPS26,RPS3A,SDC1,SDC3,SDF2,SELENOS,SKIV2L,SKIV2L2,SKP1,SMG7,SNF8,SNX25,SSB,SUPV3L1,TAF1,TBX21,THRAP3,TMEM67,TRIM9,TRIP12,TRPC4AP,UBA52,UBB,UBE2A,UBE2B,UBE2G1,UBE2K,UBE2U,UBE2Z,UBE4A,UBE4B,UBR3,UBR4,UBR5,UBXN2A,UCHL3,UGGT2,UPF1,UPF3B,USP1,USP12,USP13,USP19,USP24,USP30,USP32,USP33,USP35,USP37,USP4,USP42,USP43,USP44,USP45,USP47,USP5,USP9X,USP9Y,VLDLR,VPS37A,WDR81,XRN2,ZFP36L2,ZHX2,ZRANB1	MammalFishAncestor	129.332
GO.Biological.Process	GO:0072086	specification.of.loop.of.Henle.identity	139	1.745863e-133	2.255131e-129	1.622397e-131	4.538625e+0	IRX1,IRX2,IRX3	MammalFishAncestor	128.647
GO.Biological.Process	GO:0032374	regulation.of.cholesterol.transport	140	4.195987e-133	5.419956e-129	3.871397e-131	3.175448e+0	ABCA1,ABCA7,ABCB4,ABCG5,ABCG8,ANXA2,ARV1,LAMTOR1,LDLRAP1,LRP1,NFKBIA,PCSK9,PON1,PPARG,PTCH1,SHH,WASHC1	MammalFishAncestor	128.266
GO.Biological.Process	GO:0003279	cardiac.septum.development	141	5.620737e-133	7.260306e-129	5.149153e-131	1.742807e+0	ACVR1,ANK2,C5orf42,DHRS3,FGF8,GATA3,GATA6,GJA5,JAG1,LMO4,LRP2,LTBP1,NOTCH1,NPHP3,NRP2,PARVA,PCSK5,PITX2,PLXND1,PROX1,RARB,RBM15,SALL1,SALL4,SAV1,SMAD6,TBX1,TBX2,TGFBR3,XIRP2,ZFPM2	MammalFishAncestor	128.139
GO.Biological.Process	GO:0090407	organophosphate.biosynthetic.process	142	1.505346e-132	1.944455e-128	1.369335e-130	1.482512e+0	ABHD3,ACAT1,ACP6,ADCY5,ADCY6,ADCY7,ADCY9,ADK,ADM,ADSS,ADSSL1,AK4,AK5,AK8,AK9,AMPD2,AMPD3,APRT,ASPDH,ATIC,ATM,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP5S,ATP6V0A1,ATP6V0A2,CHPT1,CKM,CPNE1,CRYL1,DCTD,DOLK,DTYMK,DUT,ENTPD8,FGF16,FGF20,FGF5,FGF8,FIG4,GGPS1,GK2,GK3P,GNPAT,GPAT3,GPHN,HEXB,IDI1,IDI2,IMPDH2,INPP5E,INPP5F,INPPL1,IRS2,ISYNA1,KL,KLB,LHPP,LPCAT1,LPCAT2,LPCAT3,LPGAT1,LPIN2,MBIP,MBOAT2,MTMR14,MTMR7,MVK,NADK,NAXD,NME4,NMNAT1,NMNAT2,NPPA,NPPB,PAICS,PAPSS1,PCYT1B,PI4KA,PIGB,PIGC,PIGK,PIGL,PIGN,PIGO,PIGQ,PIGS,PIGV,PIGY,PIK3CB,PIK3CD,PIK3R2,PIK3R3,PIK3R4,PIK3R5,PIK3R6,PIKFYVE,PIP4K2C,PITPNM2,PLA2G4A,PLA2G4B,PNPO,PPAT,PPIP5K1,PRPS2,PTGS2,PTPN13,PYGL,PYURF,RAB4A,RFK,RRM2B,SAMD8,SBF1,SERINC5,SGMS2,SLC22A13,SLC25A13,SLC35B2,SLC35B3,SLC44A4,SLC5A8,SRD5A3,STARD7,STOML2,TAMM41,TAZ,TKT,TPI1,UCKL1,UCN2,UMPS,UPP2	MammalFishAncestor	127.711
GO.Biological.Process	GO:0061333	renal.tubule.morphogenesis	143	1.886158e-132	2.436350e-128	1.703741e-130	1.876587e+0	ADAMTS16,COL4A1,CTNNBIP1,EYA1,FAT4,FGF8,FOXD1,GATA3,GLI3,HNF1B,HOXA11,HOXD11,IRX1,IRX2,IRX3,LHX1,MEF2C,NPNT,PAX2,PGF,PKD1,PKD2,PTCH1,SALL1,SHH,SIX1,WT1	MammalFishAncestor	127.613
GO.Biological.Process	GO:0030878	thyroid.gland.development	144	3.352491e-132	4.330413e-128	3.007231e-130	3.764492e+0	FGF8,HOXA3,HOXA5,HOXB3,HOXD3,MAP2K1,NKX2-1,RAF1,SHH,SIX1,SMAD3,TBX1	MammalFishAncestor	127.363
GO.Biological.Process	GO:1902652	secondary.alcohol.metabolic.process	145	3.993969e-132	5.159010e-128	3.557938e-130	2.170357e+0	ABCA1,ACLY,ANGPTL3,APOB,ARV1,CEL,CES1,CFTR,CLN8,CUBN,CYP2R1,CYP51A1,CYP7B1,DHCR24,ERG28,GGPS1,HDLBP,HMGCR,IDI1,IDI2,INSIG1,LDLR,LDLRAP1,LEPR,LIPC,MSMO1,MT3,MVK,OSBPL1A,PCSK9,PON1,SCAP,SCARF1,SREBF1,STARD3,VLDLR	MammalFishAncestor	127.287
GO.Biological.Process	GO:0032388	positive.regulation.of.intracellular.transport	146	5.780101e-132	7.466156e-128	5.113806e-130	1.575842e+0	ACTL6A,ADORA2B,ANK3,ANXA2,ARIH2,BAG3,BAMBI,BAP1,BCAP31,BCAS3,BMP6,CEP131,CEP290,CTSK,DHX9,DPH6,DYNC1H1,EDAR,EDEM1,EFCAB7,EMD,F2R,FLNA,FYN,GAB2,GAS6,GLI3,GLS2,GPR26,GSK3B,HUWE1,HYAL2,ICE1,ITGB1BP1,JUP,KANK1,KAT2A,KIF5B,LDLRAP1,LRRC46,MED1,MFF,MICALL2,MIEF2,MTCL1,MYBPC1,NBPF3,NEDD4,NKAP,NODAL,NUMA1,NUP93,OSCP1,PAK1,PDCD5,PIK3R2,PLAGL2,PPM1A,PRKCD,PSMB7,PTGS2,PTPN23,RHOA,SAE1,SFN,SFRP2,SHH,SLC17A9,SMAD3,SPAG5,SPHK1,STARD7,SULF2,TCF7L2,TENM1,TGFB3,TLR7,TM9SF4,TMEM30A,TPR,UBL4B,UBR5,UNC13B,XPO4,ZBTB17,ZIC1	MammalFishAncestor	127.127
GO.Biological.Process	GO:0044265	cellular.macromolecule.catabolic.process	147	8.297369e-132	1.071771e-127	7.290960e-130	1.387595e+0	ACR,ADAMTS9,AFG1L,AGO1,AGO3,AGO4,AMFR,ANAPC10,ANAPC15,ANAPC7,AREL1,ARIH2,ARRDC1,ASB2,ATM,ATXN3L,AXIN1,BAP1,BTBD1,BTRC,BUB1B,BUB3,C18orf25,CELA1,CHFR,CLOCK,CLTC,CNOT7,CNOT9,CTSK,CTSS,CUL2,CUL4A,CUL4B,CUL9,CYLD,DCP1A,DCP1B,DDIT3,DDX6,DERL1,DHX34,DICER1,DIS3,DIS3L,DNA2,DNAJB9,DNAJC3,DNASE1,DNASE1L3,DNASE2B,DTL,EDEM1,EIF4B,EIF4G1,ENC1,ENDOG,ENSG00000256206,ENSG00000272772,ERLEC1,EXOSC10,EXOSC8,FAP,FBXL14,FBXL18,FBXL22,FBXL3,FBXL4,FBXL5,FBXO11,FBXO21,FBXO9,FBXW4,FOXL2,GSK3B,HERC2,HNRNPD,HPSE,HUWE1,IDE,KCTD10,KEAP1,KIF14,KLHL11,KLHL2,KLHL29,KLHL31,LAMP2,LNX1,LSM4,LSM6,METTL14,MGEA5,MVB12B,NBAS,NEDD4,NFE2L2,NGLY1,NPLOC4,NT5C3B,PABPC1,PABPC4,PAN3,PAPD4,PAPD5,PCSK9,PDE12,POMT1,POP1,PPP2CA,PSMA1,PSMA5,PSMA6,PSMA7,PSMB2,PSMB7,PSMB8,PSMB9,PSMD11,PSMD12,PSMD14,PSMD2,PSMD6,PTPN23,RAB12,RANBP1,RANBP2,RBBP6,RBX1,RLIM,RNF111,RNF165,RNF19A,RNF213,RNF216,RNF34,RNF41,RNF6,RPL10,RPL19,RPL21,RPL22,RPL27A,RPL30,RPL32,RPL35,RPL39,RPL4,RPL41,RPL5,RPL9,RPLP1,RPS10,RPS15,RPS2,RPS26,RPS3A,SDF2,SELENOS,SKIV2L,SKIV2L2,SKP1,SMG7,SNF8,SSB,SUPV3L1,TAF1,TBX21,THRAP3,TMEM67,TRIM9,TRIP12,TRPC4AP,UBA52,UBB,UBE2A,UBE2B,UBE2G1,UBE2K,UBE2U,UBE2Z,UBE4A,UBE4B,UBR3,UBR4,UBR5,UBXN2A,UCHL3,UGGT2,UPF1,UPF3B,USP1,USP12,USP13,USP19,USP24,USP30,USP32,USP33,USP35,USP37,USP4,USP42,USP43,USP44,USP45,USP47,USP5,USP9X,USP9Y,VLDLR,VPS37A,WDR81,XRN2,ZFP36L2,ZHX2,ZRANB1	MammalFishAncestor	126.97
GO.Biological.Process	GO:0003281	ventricular.septum.development	148	1.715229e-131	2.215561e-127	1.497001e-129	1.936246e+0	ACVR1,C5orf42,GATA3,GJA5,LMO4,LRP2,LTBP1,NOTCH1,PITX2,PROX1,RBM15,SALL1,SALL4,SAV1,SMAD6,TGFBR3,XIRP2,ZFPM2	MammalFishAncestor	126.655
GO.Biological.Process	GO:0046129	purine.ribonucleoside.biosynthetic.process	149	1.840603e-131	2.377507e-127	1.595642e-129	2.506110e+0	ACAT1,ADK,ADSS,ADSSL1,AK5,AK9,AMD1,APRT,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP5S,ATP6V0A1,ATP6V0A2,IMPDH2,NME4,NT5E,PAPSS1,PRPS2,PRTFDC1,SLC25A13,SLC35B2,SLC35B3,STOML2	MammalFishAncestor	126.624
GO.Biological.Process	GO:0001655	urogenital.system.development	150	2.551739e-131	3.296081e-127	2.197388e-129	1.431909e+0	ACAT1,ADAMTS16,AGTR1,ALDH1A2,ARG2,BMP6,C5orf42,CEP290,COL4A1,CRLF1,CTNNBIP1,CYP19A1,CYP7B1,DCHS2,DLG5,EMX2,ENPEP,EPHA4,ESR1,EYA1,FAT4,FBN1,FGF8,FKBP4,FOXB1,FOXD1,FRAS1,GATA3,GCNT1,GCNT3,GLI1,GLI2,GLI3,GLIS2,HNF1B,HOXA11,HOXB13,HOXC11,HOXD11,HOXD13,HYAL2,IRX1,IRX2,IRX3,ITGA6,ITGB4,JAG1,KCNJ8,LAMB2,LHX1,LZTS2,MEF2C,MMP17,MYO1E,NF1,NID1,NIPBL,NOTCH1,NPHP3,NPNT,NUP93,OSR2,PAX2,PCSK5,PCSK9,PDGFRA,PGF,PKD1,PKD2,PLCE1,POU3F3,PPAT,PROX1,PTCH1,PYGO1,RARB,RBP4,RIDA,RPGRIP1L,RRM2B,SALL1,SDC1,SEC63,SERPINF1,SHH,SIM1,SIX1,SIX2,SIX4,SMAD1,SMAD3,SMAD6,SMAD9,SMARCC1,STAT1,SULF1,SULF2,TFAP2A,TNS2,TP73,TSC1,WDPCP,WT1	MammalFishAncestor	126.482
GO.Biological.Process	GO:0010970	transport.along.microtubule	151	9.272831e-131	1.197772e-126	7.932262e-129	2.081143e+0	AP3B1,AP3B2,AP3M1,ARHGAP21,BLOC1S5,CEP131,DST,DYNC1H1,DYNC1I1,DYNC1I2,DYNC2H1,DYNC2LI1,HTT,ICK,IFT122,IFT43,IFT80,IFT81,IFT88,KIF17,KIF1A,KIF1B,KIF23,KIF3A,KIF3B,KIF3C,KIF5A,KIF5B,KLC3,LRPPRC,NDE1,NDEL1,PEX14,PRKCZ,RABL2B,RHOT1,RHOT2,SSX2IP,TNPO1,TTC21A,TTC21B,TTC30A,TTC30B,UBB,WDR19,WDR34	MammalFishAncestor	125.922
GO.Biological.Process	GO:0006066	alcohol.metabolic.process	152	2.718418e-130	3.511381e-126	2.310119e-128	1.706924e+0	ABCA1,ACLY,ALDH1A2,ALDH1A3,ANGPTL3,APOB,ARV1,CEL,CES1,CFTR,CLN8,COQ2,COQ3,CUBN,CYP2R1,CYP51A1,CYP7B1,DHCR24,DHRS3,DHRS9,ERG28,GALK1,GGPS1,GK2,GK3P,GPD2,HDLBP,HMGCR,IDI1,IDI2,INPP5A,INPP5E,INPPL1,INSIG1,IP6K2,ISYNA1,ITPK1,LDLR,LDLRAP1,LEPR,LIPC,MOGAT1,MSMO1,MT3,MTMR7,MVK,NUDT3,OSBPL1A,PCSK9,PLCB2,PLCB4,PLCD1,PLCD4,PLCE1,PLCG1,PLD4,PON1,PPIP5K1,RBP4,RDH11,RDH12,SCAP,SCARF1,SGPP2,SPHK1,SRD5A3,SREBF1,STARD3,TPI1,VLDLR	MammalFishAncestor	125.455
GO.Biological.Process	GO:0051258	protein.polymerization	153	5.999637e-130	7.749731e-126	5.065184e-128	2.310884e+0	AKAP9,CASQ1,CLASP1,COBLL1,CORO7,CSNK1D,CTTN,DIAPH1,DNM3,FGA,FGB,FGG,GPX4,HDGFL3,LMOD2,MAP7D3,MICALL2,MSRB1,MZT1,NDE1,NDEL1,NIN,PREX1,SLAIN2,TRPV4,TUBG1,TUBG2,TUBGCP4,TUBGCP5,TUBGCP6,UBE2K,VIL1,WASF1,WASF3,ZNF207	MammalFishAncestor	125.111
GO.Biological.Process	GO:0060849	regulation.of.transcription.involved.in.lymphatic.endothelial.cell.fate.commitment	154	6.394354e-130	8.259587e-126	5.363368e-128	5.443756e+0	NR2F2,PROX1	MammalFishAncestor	125.083
GO.Biological.Process	GO:0009954	proximal/distal.pattern.formation	155	7.895231e-130	1.019827e-125	6.579529e-128	2.350730e+0	ALDH1A2,CHSY1,DLX1,DLX2,GLI1,GLI2,GLI3,HOXA10,HOXA11,HOXC10,HOXC11,HOXD10,HOXD9,IRX1,IRX2,IRX3,NODAL,SIX3,SP8	MammalFishAncestor	124.991
GO.Biological.Process	GO:1901293	nucleoside.phosphate.biosynthetic.process	156	1.281704e-129	1.655577e-125	1.061267e-127	1.820714e+0	ACAT1,ADCY5,ADCY6,ADCY7,ADCY9,ADK,ADM,ADSS,ADSSL1,AK4,AK5,AK8,AK9,AMPD2,AMPD3,APRT,ASPDH,ATIC,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP5S,ATP6V0A1,ATP6V0A2,DCTD,DTYMK,DUT,ENTPD8,IMPDH2,LHPP,NADK,NAXD,NME4,NMNAT1,NMNAT2,NPPA,NPPB,PAICS,PAPSS1,PPAT,PRPS2,PTGS2,RFK,RRM2B,SLC22A13,SLC25A13,SLC35B2,SLC35B3,SLC5A8,STOML2,UCKL1,UCN2,UMPS,UPP2	MammalFishAncestor	124.781
GO.Biological.Process	GO:0002087	regulation.of.respiratory.gaseous.exchange.by.neurological.system.process	157	1.768410e-129	2.284255e-125	1.454940e-127	3.622022e+0	ATP1A2,GLRA1,GLS,GSX2,NLGN2,NLGN3,PBX3,PHOX2B,TSHZ3	MammalFishAncestor	124.641
GO.Biological.Process	GO:0032507	maintenance.of.protein.location.in.cell	158	2.271353e-129	2.933907e-125	1.856903e-127	2.480414e+0	AKT1,ANK3,CCDC22,CD4,DAG1,DZIP1,FLNA,FLNB,HK1,JUP,KEAP1,MORC3,MXI1,NFKBIA,NFKBIE,NR5A1,PDIA2,PKD1,PKD2,SHANK1,SKP1,SPAG4,SPTBN4,SRI,SYNE1,SYNE3,TAF3,TLN2,TMSB4X	MammalFishAncestor	124.533
GO.Biological.Process	GO:2000576	positive.regulation.of.microtubule.motor.activity	159	2.993865e-129	3.867175e-125	2.432186e-127	6.602740e+0	DYNC1I1,DYNC1I2,MTCL1	MammalFishAncestor	124.413
GO.Biological.Process	GO:0006367	transcription.initiation.from.RNA.polymerase.II.promoter	160	4.152997e-129	5.364426e-125	3.352766e-127	1.733440e+0	CCNC,CCNH,CDK8,DACH1,ERCC2,ESR1,ESRRB,ESRRG,GTF2A1L,GTF2A2,GTF2B,HNF4G,MED1,MED12,MED13,MED14,MED15,MED16,MNAT1,NOTCH1,NPPA,NR1I2,NR2C1,NR2C2AP,NR2E1,NR2E3,NR2F1,NR3C2,NR4A2,NR4A3,NR5A1,NR5A2,NR6A1,POLR2A,POLR2E,POLR2K,PPARG,PPM1D,RARB,RORA,RXRB,STON1-GTF2A1L,TAF1,TAF11,TAF2,TAF3,TAF4,TAF5,TAF7,TAF7L,TEAD1,THRAP3	MammalFishAncestor	124.27
GO.Biological.Process	GO:0021778	oligodendrocyte.cell.fate.specification	161	4.612003e-129	5.957324e-125	3.700201e-127	5.084017e+0	NKX2-2,PAX6,SOX6	MammalFishAncestor	124.225
GO.Biological.Process	GO:0030031	cell.projection.assembly	162	1.048096e-128	1.353826e-124	8.356948e-127	1.503769e+0	ABCC4,AKAP9,ARHGEF26,ARHGEF6,ARMC4,ATP6V1D,BBIP1,BBS10,BBS2,BBS5,C5orf42,CC2D2A,CCDC39,CCDC63,CCNO,CEP131,CEP135,CEP152,CEP164,CEP192,CEP290,CEP76,CFAP46,CFAP74,CLASP1,CSNK1D,CTTN,CYFIP1,DCTN2,DNAAF4,DNAH1,DNAH5,DNAH7,DNAH8,DNM3,DRC1,DYNC1H1,DYNC1I2,DYNC2H1,DYNC2LI1,DZIP1,ENSG00000248710,ENSG00000251569,FAM161A,FBF1,FGD6,FLNA,FOPNL,FSCN1,GALNT11,HAUS1,HSP90AA1,ICK,IFT122,IFT43,IFT80,IFT81,IFT88,INPPL1,IQUB,ITGA6,KIF17,KIF3A,KIF3B,KIF3C,KIT,KLF5,LPAR3,MARK4,MKKS,NDE1,NEK1,NEK2,NEURL1,NOTCH1,NPHP3,NTN1,ODF2,OFD1,ONECUT1,ONECUT2,P2RY12,PARVA,PIBF1,PPP1R9B,PTPN23,RAB11A,RAB23,RABL2B,RAPGEF2,RAPGEF6,RFX4,RILP,RILPL1,RILPL2,ROCK1,RPGRIP1L,S1PR2,SDCCAG8,SEPT2,SHTN1,SNAP29,SPAG1,SPAG17,SSX2IP,TCTN1,TCTN2,TEKT2,TMEM67,TNIK,TNPO1,TRIM59,TTC21B,TTC30A,TTC30B,TTC8,TTLL5,TUBA4A,TUBB4B,TUBG1,UBE2B,VCL,WASF3,WDPCP,WDR19,WDR34,WHAMM,ZMYND10	MammalFishAncestor	123.868
GO.Biological.Process	GO:0002009	morphogenesis.of.an.epithelium	163	2.908038e-127	3.756313e-123	2.304486e-125	1.390453e+0	ACVR1,ADAM17,ADAMTS16,ADM,ALDH1A2,ALDH1A3,ARHGAP12,ARID1A,ATP7A,BBS5,BTRC,C5orf42,CC2D2A,CCDC39,CEP290,CLIC4,COL4A1,CTHRC1,CTNNBIP1,CYP7B1,DAG1,DLG5,DLL4,DVL2,EDNRA,EPHA4,ESR1,EYA1,FAT4,FGF8,FLNA,FOLR1,FOXD1,FOXN4,FRAS1,FREM2,FZD6,GATA3,GCM1,GDF7,GLI2,GLI3,GLMN,HHIP,HNF1B,HOXA11,HOXA5,HOXB13,HOXB2,HOXB4,HOXD11,HOXD13,IFT122,IRX1,IRX2,IRX3,JAG1,KAT2A,KDM2B,KDM5B,LEF1,LHX1,LIAS,LMO4,LRP2,MED1,MED12,MEF2C,MEGF8,MET,MIB1,MICAL2,MKKS,MPP5,MYCN,MYO9A,NKX2-1,NODAL,NOTCH1,NPHP3,NPNT,NRARP,NTN1,PAK1,PAX2,PDX1,PGF,PHB2,PITX2,PKD1,PKD2,PLXNB2,PLXND1,PRKACB,PRKD2,PROX1,PTCH1,RAB10,RBM15,RHOA,RHOB,RIPK4,RPGRIP1L,RYR2,SALL1,SALL4,SETD2,SFRP2,SHH,SIX1,SIX2,SMAD3,SOX18,STARD13,STK3,TBX2,TBX4,TCAP,TCTN1,TFAP2A,TSC1,TSC2,VCL,WNT7A,WT1,ZEB2	MammalFishAncestor	122.425
GO.Biological.Process	GO:0045599	negative.regulation.of.fat.cell.differentiation	164	4.085852e-127	5.277695e-123	3.218107e-125	2.252199e+0	ANKRD26,ASXL1,AXIN1,DDIT3,GATA3,GPS2,INSIG1,JAG1,JDP2,RORA,SMAD3,SORT1,TRIO,TRPV4,ZADH2,ZFP36L2,ZFPM2	MammalFishAncestor	122.278
GO.Biological.Process	GO:1902582	single-organism.intracellular.transport	165	1.728133e-126	2.232229e-122	1.352866e-124	1.426899e+0	ABCA1,ACACA,ACACB,AKT1,AP3B1,AP3B2,AP3M1,ARHGAP21,ATG4B,ATG4C,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5G1,ATP5G3,ATP5L,ATP5S,BBS2,BBS5,BLOC1S5,CADPS,CEP131,CES1,CHGA,CLIP1,COL4A3BP,CPT1B,CSE1L,DAG1,DCTN2,DNAJC5,DNAJC6,DNLZ,DNM3,DST,DYNC1H1,DYNC1I1,DYNC1I2,DYNC2H1,DYNC2LI1,FAM53B,FCHO2,GPN3,GRPEL1,HEATR3,HSP90AA1,HSPA4,HTT,ICK,ICMT,IFT122,IFT43,IFT80,IFT81,IFT88,IPO9,KIF17,KIF1A,KIF1B,KIF23,KIF3A,KIF3B,KIF3C,KIF5A,KIF5B,KIT,KLC3,KPNA2,KPNA4,LDLR,LDLRAP1,LIN7A,LRPPRC,MKKS,MT3,MYO5A,MYO7A,NCKIPSD,NDE1,NDEL1,NDUFA13,NFKBIA,NLGN2,NLGN3,NR4A3,NUP133,NUP188,NUP210,NUP214,NUP93,OTOF,PACSIN1,PAM16,PARD3,PCLO,PEX14,PEX2,PEX5,PEX5L,PHB2,PIK3CD,PRKCZ,RAB11A,RAB27A,RAB3A,RABL2B,RAN,RANBP1,RANBP2,RERE,RHOT1,RHOT2,RILPL1,RILPL2,RIMS2,RPL10,RPL19,RPL21,RPL22,RPL27A,RPL30,RPL32,RPL35,RPL39,RPL4,RPL41,RPL5,RPL9,RPLP1,RPS10,RPS15,RPS2,RPS26,RPS3A,SAR1A,SEC24A,SEC24C,SEC24D,SEC31A,SEC63,SEH1L,SH3GL2,SIX2,SIX3,SLC25A20,SNAP23,SNAP25,SNAP29,SNUPN,SPTBN1,SRP14,SRP54,SRP68,SRP72,SSB,SSX2IP,STAT3,STOML2,STX2,SYP,SYT1,SYT2,SYT3,TAP1,TNPO1,TNPO3,TOB1,TOMM20,TPR,TRAM1,TRIM9,TSC1,TSC2,TTC21A,TTC21B,TTC30A,TTC30B,UBA52,UBB,UNC13B,UNC13C,WASL,WDR19,WDR34,WNT7A,ZFYVE9	MammalFishAncestor	121.651
GO.Biological.Process	GO:0071331	cellular.response.to.hexose.stimulus	166	1.741045e-126	2.248908e-122	1.354764e-124	2.307815e+0	ENDOG,FOXO3,GAS6,GCLC,GCLM,GJB6,ICAM1,IRS2,KCNJ11,MEN1,PAX2,PDK3,POLG,PTPRN,PTPRN2,RAB11FIP2,RAF1,RAP1A,SERPINF1,SIN3A,SLC26A6,SLC2A5,TWNK,UNC13B,ZNF236	MammalFishAncestor	121.648
GO.Biological.Process	GO:0000395	mRNA.5'-splice.site.recognition	167	6.525841e-126	8.429429e-122	5.047562e-124	5.725976e+0	PSIP1,SFSWAP,SNRPC	MammalFishAncestor	121.074
GO.Biological.Process	GO:0009167	purine.ribonucleoside.monophosphate.metabolic.process	168	6.676982e-126	8.624658e-122	5.133725e-124	1.835991e+0	ADK,ADSS,ADSSL1,AFG1L,AK4,AK5,AK9,ALDOC,AMPD2,AMPD3,APRT,ATIC,ATP1A2,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP5S,ATP6V0A1,ATP6V0A2,ATP6V1A,COX6C,COX7B,COX8C,DLD,DLG4,ENO1,ENO2,ENO4,ENSG00000266953,GALK1,GAPDH,GPI,HK1,HKDC1,IMPDH2,LHPP,MAGI3,MYH3,MYH4,MYH8,NADK,NDUFA1,NDUFA12,NDUFA13,NDUFA5,NDUFAF7,NDUFB10,NDUFB5,NDUFS1,NDUFS6,NDUFS7,NDUFV2,NMNAT1,NT5C2,NT5E,NUDT3,OGDH,OLA1,PAICS,PFKM,PGAM4,PGK1,PGM1,PPAT,PRPS2,SLC25A13,STOML2,TAZ,TPI1,UQCRHL,UQCRQ	MammalFishAncestor	121.064
GO.Biological.Process	GO:2000675	negative.regulation.of.type.B.pancreatic.cell.apoptotic.process	169	7.852783e-126	1.014344e-121	6.002035e-124	5.763609e+0	PDX1,TCF7L2	MammalFishAncestor	120.994
GO.Biological.Process	GO:0009126	purine.nucleoside.monophosphate.metabolic.process	170	1.628583e-125	2.103641e-121	1.237436e-123	1.834061e+0	ADK,ADSS,ADSSL1,AFG1L,AK4,AK5,AK9,ALDOC,AMPD2,AMPD3,APRT,ATIC,ATP1A2,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP5S,ATP6V0A1,ATP6V0A2,ATP6V1A,COX6C,COX7B,COX8C,DLD,DLG4,ENO1,ENO2,ENO4,ENSG00000266953,GALK1,GAPDH,GPI,HK1,HKDC1,IMPDH2,LHPP,MAGI3,MYH3,MYH4,MYH8,NADK,NDUFA1,NDUFA12,NDUFA13,NDUFA5,NDUFAF7,NDUFB10,NDUFB5,NDUFS1,NDUFS6,NDUFS7,NDUFV2,NMNAT1,NT5C2,NT5E,NUDT3,OGDH,OLA1,PAICS,PFKM,PGAM4,PGK1,PGM1,PPAT,PRPS2,SLC25A13,STOML2,TAZ,TPI1,UQCRHL,UQCRQ	MammalFishAncestor	120.677
GO.Biological.Process	GO:1903829	positive.regulation.of.cellular.protein.localization	171	1.878337e-125	2.426248e-121	1.418858e-123	1.491755e+0	ACSL3,ACTL6A,AKT1,ANK3,ARHGEF16,ARIH2,BAG3,BAMBI,BAP1,BCAP31,BCAS3,BMF,BMP6,CCT4,CDK5RAP3,CDT1,CEP131,CEP290,CTSK,CYLD,DPH6,EDAR,EDEM1,EFCAB7,EMD,F2R,FLNA,FYN,GAS6,GLI3,GLIS2,GLS2,GPR26,GPSM2,GSK3B,HUWE1,HYAL2,ICE1,ITGB1BP1,JUP,KANK1,KAT2A,KCNJ11,KIF5B,LRIG2,LRP1,LRRC46,MAPK8,MED1,MFF,MICALL2,MIEF2,MTCL1,MYBPC1,NBPF3,NKAP,NODAL,NUMA1,NUP93,OSCP1,PAK1,PDCD5,PIK3R2,PLAGL2,PPM1A,PPP1R13B,PRKCD,PSMB7,PTGS2,RAB11A,RAB11FIP2,RHOA,RTN4,SAE1,SFN,SFRP2,SHH,SLC17A9,SMAD3,SNX33,SPHK1,SPTBN1,SSH1,STARD7,STK11,SULF2,TCF7L2,TENM1,TFDP1,TGFB3,TLR7,TM9SF4,TMEM30A,TP73,TPR,UBL4B,UBR5,VIL1,WASHC1,WNK3,XPO4,YWHAQ,YWHAZ,ZBTB17,ZIC1	MammalFishAncestor	120.615
GO.Biological.Process	GO:0070918	production.of.small.RNA.involved.in.gene.silencing.by.RNA	172	9.692726e-125	1.252009e-120	7.279125e-123	3.341906e+0	AGO1,AGO3,AGO4,DGCR8,DICER1,PRKRA,PUM1,PUM2,SMAD1,SMAD3,ZC3H7B	MammalFishAncestor	119.902
GO.Biological.Process	GO:0030099	myeloid.cell.differentiation	173	1.017461e-124	1.314254e-120	7.596846e-123	1.744554e+0	ABI1,ANXA2,BATF,CBFA2T3,CSF2,DCSTAMP,EFNA2,EIF2AK1,EP300,ERCC2,EVI2B,F2RL1,FARP2,FOXP1,GAB2,GATA3,HOXB7,INHA,INHBA,KIT,LEF1,LRRK1,MED1,MEF2C,MEIS1,MT1G,NFE2L1,NKAP,OSTM1,PIK3CD,PPARG,PRTN3,PTPN2,PTPN6,RASGRP4,SBNO2,SH3PXD2A,SLC11A2,SOX6,SP3,TCTA,TET2,TGFBR3,TNFRSF11A,TNFSF11,VPS33A	MammalFishAncestor	119.881
GO.Biological.Process	GO:0002573	myeloid.leukocyte.differentiation	174	1.479608e-124	1.911210e-120	1.098396e-122	2.027279e+0	ANXA2,BATF,CBFA2T3,CSF2,DCSTAMP,EFNA2,EIF2AK1,F2RL1,FARP2,FOXP1,GAB2,GATA3,KIT,LEF1,LRRK1,MED1,MEF2C,MT1G,NKAP,OSTM1,PIK3CD,PPARG,PRTN3,SBNO2,SH3PXD2A,SP3,TCTA,TNFRSF11A,TNFSF11	MammalFishAncestor	119.719
GO.Biological.Process	GO:0033157	regulation.of.intracellular.protein.transport	175	2.510089e-124	3.242282e-120	1.852733e-122	1.504011e+0	ACTL6A,ANK3,ARIH2,BAG3,BAMBI,BAP1,BCAP31,BCAS3,BMP6,CCDC22,CEP131,CEP290,CTSK,CYLD,DACT3,DPH6,EDAR,EDEM1,EFCAB7,EMD,ERLEC1,F2R,FLNA,FYN,GAS6,GCC2,GLI3,GLS2,GPR26,GSK3B,HUWE1,HYAL2,ICE1,ITGB1BP1,JUP,KANK1,KAT2A,KEAP1,KIF5B,LRRC46,MDFIC,MED1,MFF,MICALL2,MIEF2,MTCL1,MTOR,MXI1,MYBPC1,NBPF3,NDEL1,NF1,NFKBIA,NFKBIE,NKAP,NODAL,NOV,NUP93,OSCP1,PAK1,PDCD5,PIK3R2,PKD1,PKD2,PLAGL2,PPM1A,PPM1B,PRKCD,PSMB7,PTGS2,PTPN14,RAB23,RANGAP1,RHOA,SAE1,SFN,SFRP2,SHH,SLC17A9,SMAD3,SPHK1,SREBF1,SRI,STARD7,SULF2,TCF7L2,TENM1,TGFB3,TLR7,TM9SF4,TMEM30A,TMSB4X,TPR,UBL4B,UBR5,XPO1,XPO4,ZBTB17,ZIC1	MammalFishAncestor	119.489
GO.Biological.Process	GO:2001182	regulation.of.interleukin-12.secretion	176	2.712017e-124	3.503112e-120	1.990405e-122	6.545217e+0	FOXP1,MAPK11,TLR8	MammalFishAncestor	119.456
GO.Biological.Process	GO:0048048	embryonic.eye.morphogenesis	177	6.527712e-124	8.431846e-120	4.763755e-122	2.373805e+0	ALDH1A3,ARID1A,AXIN1,FBN1,FBN2,FOXL2,KDM2B,PAX2,PAX6,PROX1,RARB,SIX3,SP3,TBX2,TFAP2A,ZEB1	MammalFishAncestor	119.074
GO.Biological.Process	GO:0031503	protein.complex.localization	178	7.405810e-124	9.566085e-120	5.374205e-122	2.439214e+0	CEP131,DYNC2H1,DYNC2LI1,EXOC1,EXOC8,FKBP4,GPN3,ICK,IFT122,IFT43,IFT80,IFT81,IFT88,KIF17,KIF3A,KIF3B,KIF3C,MZT1,NACC2,NUP133,RABL2B,SEH1L,SSX2IP,TNPO1,TTC21A,TTC21B,TTC30A,TTC30B,WASL,WDR19,WDR34	MammalFishAncestor	119.019
GO.Biological.Process	GO:1903827	regulation.of.cellular.protein.localization	179	1.184606e-123	1.530156e-119	8.548355e-122	1.385448e+0	ACSL3,ACTL6A,AKT1,ANK3,APPL1,ARHGEF16,ARIH2,BAG3,BAMBI,BAP1,BCAP31,BCAS3,BMF,BMP6,CCDC22,CCNE1,CCT4,CDK5RAP3,CDT1,CEP131,CEP290,CLTC,CTSK,CYLD,DACT3,DCLK1,DCLK2,DPH6,EDAR,EDEM1,EFCAB7,EMD,ERLEC1,F2R,FLNA,FYN,GAS6,GBF1,GBP1,GCC2,GLI3,GLIS2,GLS2,GPM6B,GPR26,GPSM2,GSK3B,HFE,HUWE1,HYAL2,ICE1,ITGB1BP1,JUP,KALRN,KANK1,KAT2A,KCNAB2,KCNJ11,KEAP1,KIF5B,LDLRAP1,LRIG2,LRP1,LRRC46,LZTS2,MAPK8,MDFIC,MED1,MFF,MICALL2,MIEF2,MTCL1,MTOR,MXI1,MYBPC1,NBPF3,NDEL1,NF1,NFKBIA,NFKBIE,NKAP,NODAL,NOV,NUMA1,NUP93,OSCP1,PAK1,PDCD5,PIK3R2,PKD1,PKD2,PLAGL2,PPFIA1,PPM1A,PPM1B,PPP1R13B,PPP2R5A,PRKCD,PSMB7,PTGS2,PTPN14,RAB11A,RAB11FIP2,RAB23,RANGAP1,RHOA,RTN4,SAE1,SETD2,SFN,SFRP2,SHH,SIN3A,SLC17A9,SMAD3,SNX33,SPHK1,SPTBN1,SREBF1,SRI,SSH1,STARD7,STK11,STX8,SULF2,TCF7L2,TENM1,TFDP1,TGFB3,TLR7,TM9SF4,TMEM30A,TMSB4X,TP73,TPR,UBL4B,UBR5,VIL1,VTI1B,WASHC1,WNK3,XPO1,XPO4,YWHAQ,YWHAZ,ZBTB17,ZIC1	MammalFishAncestor	118.815
GO.Biological.Process	GO:0060537	muscle.tissue.development	180	1.402529e-123	1.811647e-119	1.006470e-121	1.473373e+0	ACTA1,ACTC1,ACVR1,ADAMTS9,ALDH1A2,ARID1A,ASB2,BCL9,BCL9L,CASQ1,CHRNA1,COL11A1,COL19A1,COPS2,DLL4,DNER,EMD,EP300,EYA1,FLNB,FOS,FOXL2,FOXN2,FOXP2,GATA6,GJA5,GPX1,GTF3C5,HOMER1,HOXD10,HOXD9,KAT2A,KDM6B,KLF5,KLHL40,KLHL41,LRP2,MED1,MEF2C,MSC,MTOR,MYBPC3,MYF5,MYF6,MYH11,MYL2,MYL6B,MYOM1,MYOM2,NDUFV2,NEURL1,NEXN,NF1,NOTCH1,NPPA,NPPB,NR2F2,OBSL1,P2RX2,PDGFRA,PHOX2B,PITX1,PITX2,PKD2,POU4F1,PROX1,PROX2,RARB,RBP4,RYR1,RYR2,SGCG,SHH,SIX1,SIX4,SMAD1,SOX6,SRPK3,STAC3,TAZ,TBX2,TCAP,TENM4,TGFBR3,TNNC1,TNNI1,TNNT2,TPM1,TSC1,UBE4B,VAX1,WNT2,WT1,XIRP2,ZBTB18,ZFPM2	MammalFishAncestor	118.742
GO.Biological.Process	GO:0099131	ATP.hydrolysis.coupled.ion.transmembrane.transport	181	2.613109e-123	3.375353e-119	1.864836e-121	2.639008e+0	ABCB11,ABCC1,ABCC10,ABCC3,ABCC4,ABCC6,ABCC8,ABCC9,ATP13A3,ATP1A2,ATP1A4,ATP2A2,ATP2A3,ATP2C1,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP6V0A1,ATP6V0A2,ATP6V1A,ATP6V1F,ATP7A,CFTR	MammalFishAncestor	118.472
GO.Biological.Process	GO:0045596	negative.regulation.of.cell.differentiation	182	5.164880e-123	6.671475e-119	3.665646e-121	1.311144e+0	ABCA1,ABCC8,ADCY6,ADGRV1,ANKRD26,ASXL1,AXIN1,BAG5,BHLHA15,BHLHE41,C16orf45,CAPN3,CDK12,CDKL3,CERS2,CHADL,CORO1C,CTDP1,CTR9,CUL4A,CYLD,DACT3,DDIT3,DDX6,DENND5A,DICER1,DLX1,DLX2,DNM3,DRD3,EDNRB,EIF2AK4,EPHA4,ESRRB,FBN1,FKBP4,FOXA2,FOXO3,FSTL4,GATA3,GBP1,GFI1,GLI2,GLI3,GORASP1,GPS2,GSK3B,H1FOO,HIST1H4A,HIST1H4B,HIST1H4C,HIST1H4D,HIST1H4E,HIST1H4F,HIST1H4H,HOXA5,HOXA7,HOXA9,HOXB8,ID2,INHA,INHBA,INPP5F,INSIG1,IRX3,ISL2,ITGB1BP1,JAG1,JDP2,KANK1,KCTD11,KDM4A,LDB1,LDLRAD4,LRIG2,LRP1,MCF2,MED1,MEIS1,MEIS2,MEN1,MIB1,MT3,MYCN,N4BP2L2,NF1,NFE2L2,NFKBIA,NKX2-1,NKX2-2,NKX6-1,NKX6-2,NLGN3,NODAL,NOTCH1,NOV,NPHP3,NR2E1,NR2F1,NRARP,NTN1,OMG,P2RY12,PAK1,PAQR3,PAX6,PDCD4,PHOX2B,PITX3,PLPP7,POSTN,POU4F2,PPARG,PPP2CA,PRDM6,PTBP1,PTCH1,PTPN2,PTPRG,PTPRS,RAPGEF2,RARB,RBM15,RHOA,RNF6,RORA,RTN4,RTN4RL1,SEMA3F,SEZ6,SFRP2,SHH,SIX2,SIX3,SIX4,SKOR1,SMAD3,SORT1,SOX2,SOX6,SPART,SPDEF,STAT1,STAT3,STAT5B,SUZ12,TBX1,TBX21,TCTA,THOC2,TOB1,TOB2,TP73,TRIM11,TRIO,TRPV4,TSC1,TWSG1,USH2A,VASN,VAX1,WNT7A,ZADH2,ZBTB46,ZEB1,ZFP36L2,ZFPM2,ZHX2,ZNF536	MammalFishAncestor	118.176
GO.Biological.Process	GO:0030705	cytoskeleton-dependent.intracellular.transport	183	6.350460e-123	8.202889e-119	4.482453e-121	1.952201e+0	AP3B1,AP3B2,AP3M1,ARHGAP21,BLOC1S5,CEP131,DST,DYNC1H1,DYNC1I1,DYNC1I2,DYNC2H1,DYNC2LI1,HTT,ICK,IFT122,IFT43,IFT80,IFT81,IFT88,KIF17,KIF1A,KIF1B,KIF23,KIF3A,KIF3B,KIF3C,KIF5A,KIF5B,KIF5C,KLC3,LRPPRC,MYO5A,NDE1,NDEL1,PEX14,PRKCZ,RABL2B,RHOT1,RHOT2,SSX2IP,TNPO1,TTC21A,TTC21B,TTC30A,TTC30B,UBB,WASL,WDR19,WDR34	MammalFishAncestor	118.086
GO.Biological.Process	GO:0071326	cellular.response.to.monosaccharide.stimulus	184	1.663729e-122	2.149039e-118	1.167956e-120	2.272617e+0	ENDOG,FOXO3,GAS6,GCLC,GCLM,GJB6,ICAM1,IRS2,KCNJ11,MEN1,PAX2,PDK3,POLG,PTPRN,PTPRN2,RAB11FIP2,RAF1,RAP1A,SERPINF1,SIN3A,SLC26A6,SLC2A5,TWNK,UNC13B,ZNF236	MammalFishAncestor	117.668
GO.Biological.Process	GO:0008203	cholesterol.metabolic.process	185	2.570080e-122	3.319772e-118	1.794472e-120	2.143314e+0	ABCA1,ACLY,ANGPTL3,APOB,ARV1,CEL,CES1,CFTR,CLN8,CUBN,CYP51A1,CYP7B1,DHCR24,GGPS1,HDLBP,HMGCR,IDI1,IDI2,INSIG1,LDLR,LDLRAP1,LEPR,LIPC,MSMO1,MT3,MVK,OSBPL1A,PCSK9,PON1,SCAP,SCARF1,SREBF1,STARD3,VLDLR	MammalFishAncestor	117.479
GO.Biological.Process	GO:1904951	positive.regulation.of.establishment.of.protein.localization	186	3.161330e-122	4.083490e-118	2.195425e-120	1.431589e+0	ACSL3,ACTL6A,ANK3,ARIH2,BAG3,BAMBI,BAP1,BCAP31,BCAS3,BMF,BMP6,CCT4,CEP131,CEP290,CFTR,CRH,CTSK,DHX36,DHX9,DPH6,EDAR,EDEM1,EFCAB7,EMD,EXOC1,F2R,F2RL1,FGA,FGB,FGG,FLNA,FYN,GAPDH,GAS6,GATA3,GCG,GLI3,GLMN,GLS2,GOLPH3L,GPI,GPR26,GPR27,GSK3B,HCAR2,HK1,HUWE1,HYAL2,ICE1,IFIH1,IRS2,ITGB1BP1,JUP,KANK1,KAT2A,KIF5B,LRP1,LRRC46,MAPK11,MAPK8,MBP,MED1,MFF,MICALL2,MIEF2,MTCL1,MYBPC1,MYO18A,MYOM1,NBPF3,NKAP,NKX6-1,NLGN2,NOD2,NODAL,NUP93,OSCP1,PAK1,PDCD5,PDX1,PFKM,PIK3R2,PLAGL2,POSTN,PPIA,PPID,PPM1A,PPP1R13B,PPP3CB,PRKCD,PRKCZ,PSMB7,PTGS2,PTPN23,RBP4,RGCC,RHOA,SAE1,SEC24A,SFN,SFRP2,SHH,SLC17A9,SMAD3,SPHK1,SPTBN1,SRI,STARD7,SULF2,TARDBP,TCF7L2,TENM1,TFDP1,TGFB3,TLR7,TLR8,TM9SF4,TMEM30A,TP73,TPR,TRPV4,UBL4B,UBR5,UNC13B,XPO4,YWHAQ,YWHAZ,ZBTB17,ZIC1	MammalFishAncestor	117.389
GO.Biological.Process	GO:0060838	lymphatic.endothelial.cell.fate.commitment	187	3.274203e-122	4.229288e-118	2.261651e-120	5.098698e+0	NR2F2,PROX1	MammalFishAncestor	117.374
GO.Biological.Process	GO:0042147	retrograde.transport,.endosome.to.Golgi	188	5.203503e-122	6.721365e-118	3.575194e-120	2.469386e+0	ANKFY1,ARFRP1,ARL1,CLN5,CLTC,DENND5A,ERC1,EVI5,FAM109A,GBF1,GCC2,PIKFYVE,RAB9A,SNX2,SPAG9,STX10,TBC1D14,TBC1D5,TMEM87A,UBE2O,VPS26A,VPS29,VPS54,VTI1A,VTI1B,WASHC1,ZFYVE21	MammalFishAncestor	117.173
GO.Biological.Process	GO:0007519	skeletal.muscle.tissue.development	189	7.386701e-122	9.541402e-118	5.048361e-120	1.882699e+0	ACTA1,ASB2,BCL9,BCL9L,CASQ1,CHRNA1,COL19A1,COPS2,DNER,EMD,EP300,FLNB,FOS,FOXL2,FOXN2,FOXP2,GPX1,GTF3C5,HOMER1,HOXD10,HOXD9,KLF5,KLHL40,KLHL41,MEF2C,MSC,MYF5,MYF6,MYL6B,MYOM1,MYOM2,NEURL1,NF1,NOTCH1,NR2F2,P2RX2,PHOX2B,PITX1,PITX2,RYR1,SIX1,SIX4,SRPK3,STAC3,TAZ,VAX1,ZBTB18	MammalFishAncestor	117.02
GO.Biological.Process	GO:0035672	oligopeptide.transmembrane.transport	190	7.622203e-122	9.845600e-118	5.181895e-120	7.970820e+0	ABCB9,ABCC1,CDH17,SLC15A1	MammalFishAncestor	117.007
GO.Biological.Process	GO:0031333	negative.regulation.of.protein.complex.assembly	191	9.634746e-122	1.244520e-117	6.515812e-120	1.962449e+0	ARFGEF1,CAPZA1,CAPZA2,CLDN7,CTNNBIP1,DDX3X,FKBP4,GSK3B,HIP1R,IMPACT,KANK1,KIF14,LDLRAD4,LMO4,LMOD2,MKKS,PEX14,PEX5,PPM1A,PRKCD,PRKCZ,RAF1,SMAD6,SPTA1,SPTAN1,SPTBN1,SPTBN2,SPTBN4,TMSB4X,TRIM9,ULK1,VDAC2,VIL1,VILL,ZNF451	MammalFishAncestor	116.905
GO.Biological.Process	GO:0008306	associative.learning	192	3.406176e-121	4.399758e-117	2.291540e-119	2.139366e+0	ABCC8,ATP1A2,CRH,DRD3,FOS,FOXB1,HMGCR,HRH1,KIT,KMT2A,MEIS2,MTOR,NEUROD2,NF1,NLGN3,NPS,NPTX2,PIAS1,PPP1R1B,RELN,SHANK1,SNAP25,TANC1,TBR1,UCN	MammalFishAncestor	116.357
GO.Biological.Process	GO:0042552	myelination	193	3.947393e-121	5.098848e-117	2.641890e-119	2.022272e+0	ADAM22,AKT1,AMIGO1,ANK2,ARHGEF10,CNTNAP1,DAG1,DHH,DICER1,EIF2B2,ERCC2,FIG4,GNPAT,HEXB,MBP,MPP5,MYO5A,MYOC,NAB1,NF1,NKX6-2,PARD3,PIKFYVE,POU3F1,POU3F2,SBF2,SCN2A,SCN8A,SERINC5,TENM4,TSC1	MammalFishAncestor	116.293
GO.Biological.Process	GO:0001656	metanephros.development	194	4.087741e-121	5.280135e-117	2.721719e-119	1.819458e+0	ACAT1,DLG5,EYA1,FBN1,FGF8,FOXD1,FRAS1,GATA3,GLI3,HOXA11,HOXC11,IRX1,IRX2,IRX3,LAMB2,LHX1,NF1,NIPBL,OSR2,PAX2,PDGFRA,PKD1,PKD2,POU3F3,PTCH1,SALL1,SHH,SIX1,SIX2,SIX4,STAT1,WT1	MammalFishAncestor	116.277
GO.Biological.Process	GO:0061767	negative.regulation.of.lung.blood.pressure	195	1.163942e-120	1.503464e-116	7.710071e-119	1.314449e+1	SMAD3	MammalFishAncestor	115.823
GO.Biological.Process	GO:0061373	mammillary.axonal.complex.development	196	6.043262e-120	7.806082e-116	3.982695e-118	6.107306e+0	FOXB1,ZEB2	MammalFishAncestor	115.108
GO.Biological.Process	GO:0051222	positive.regulation.of.protein.transport	197	1.528937e-119	1.974928e-115	1.002501e-117	1.443509e+0	ACSL3,ACTL6A,ANK3,ARIH2,BAG3,BAMBI,BAP1,BCAP31,BCAS3,BMP6,CEP131,CEP290,CFTR,CRH,CTSK,DHX36,DHX9,DPH6,EDAR,EDEM1,EFCAB7,EMD,EXOC1,F2R,F2RL1,FGA,FGB,FGG,FLNA,FYN,GAPDH,GAS6,GATA3,GCG,GLI3,GLMN,GLS2,GOLPH3L,GPI,GPR26,GPR27,GSK3B,HCAR2,HK1,HUWE1,HYAL2,ICE1,IFIH1,IRS2,ITGB1BP1,JUP,KANK1,KAT2A,KIF5B,LRP1,LRRC46,MAPK11,MBP,MED1,MFF,MICALL2,MIEF2,MTCL1,MYBPC1,MYO18A,MYOM1,NBPF3,NKAP,NKX6-1,NLGN2,NOD2,NODAL,NUP93,OSCP1,PAK1,PDCD5,PDX1,PFKM,PIK3R2,PLAGL2,POSTN,PPIA,PPID,PPM1A,PPP3CB,PRKCD,PRKCZ,PSMB7,PTGS2,PTPN23,RBP4,RGCC,RHOA,SAE1,SEC24A,SFN,SFRP2,SHH,SLC17A9,SMAD3,SPHK1,SPTBN1,SRI,STARD7,SULF2,TARDBP,TCF7L2,TENM1,TGFB3,TLR7,TLR8,TM9SF4,TMEM30A,TPR,TRPV4,UBL4B,UBR5,UNC13B,XPO4,ZBTB17,ZIC1	MammalFishAncestor	114.704
GO.Biological.Process	GO:0033365	protein.localization.to.organelle	198	1.796396e-119	2.320405e-115	1.171922e-117	1.420418e+0	ABCA7,AKT1,ANK2,AP3B1,AP3M1,ARFRP1,ARL1,ARL5A,ATP6V1D,ATRX,BBIP1,BBS2,BCAP31,BMF,BRCA2,BUB1B,C5orf42,CC2D2A,CEP131,CNEP1R1,CNTLN,COL1A1,CSE1L,CSNK1D,CTDNEP1,DAG1,DCP1A,DCTN2,DDIT3,DDX1,DDX3X,DHX9,DIAPH1,DNAJB6,DNAJC19,DNLZ,DYNC2H1,ESR1,FAM53B,GBF1,GCC2,GNPTAB,GPN3,GRPEL1,HEATR3,HK1,HSP90AA1,HSPA4,IFT122,IMMP1L,IMMP2L,IPO9,KPNA2,KPNA4,LAMP1,LAMP2,LAMTOR5,LARS,MARCH5,MFF,MFN2,MOAP1,MORC3,MT3,MTX2,MTX3,NABP2,NCKIPSD,NDUFA13,NEDD4,NFKBIA,NR5A1,NUP133,NUP188,NUP214,OBSCN,OBSL1,OSBPL8,PACS1,PAM16,PAQR3,PAX6,PDIA2,PEX14,PEX2,PEX5,PEX5L,PHB2,PIBF1,PIK3R4,PIKFYVE,PLRG1,PMM1,PMPCA,PYGO1,RAB10,RAB11A,RAB11FIP3,RAB35,RAN,RANBP1,RANBP2,RERE,RPA1,RPF2,RPL10,RPL19,RPL21,RPL22,RPL27A,RPL30,RPL32,RPL35,RPL39,RPL4,RPL41,RPL5,RPL9,RPLP1,RPS10,RPS15,RPS2,RPS26,RPS3A,RRS1,RYR2,SEC63,SHH,SIX1,SIX2,SIX3,SIX4,SKP1,SLF1,SLF2,SNF8,SNUPN,SPAG5,SPTBN1,SRGN,SRP14,SRP54,SRP68,SRP72,SSB,STAT3,SYNE1,SZT2,TAF3,TCTN1,TMEM30A,TNPO1,TNPO3,TOB1,TOMM20,TPR,TSC2,TSPAN10,TTC21A,TTC21B,TUB,UBA52,VPS41,VTI1A,VTI1B,XPO1,ZFYVE9	MammalFishAncestor	114.634
GO.Biological.Process	GO:0071333	cellular.response.to.glucose.stimulus	199	3.690398e-119	4.766887e-115	2.395421e-117	2.271642e+0	ENDOG,FOXO3,GAS6,GCLC,GCLM,GJB6,ICAM1,IRS2,KCNJ11,MEN1,PAX2,PDK3,POLG,PTPRN,PTPRN2,RAB11FIP2,RAF1,RAP1A,SERPINF1,SIN3A,TWNK,UNC13B,ZNF236	MammalFishAncestor	114.322
GO.Biological.Process	GO:0001822	kidney.development	200	4.210754e-119	5.439031e-115	2.719515e-117	1.451932e+0	ACAT1,ADAMTS16,AGTR1,ALDH1A2,ARG2,BMP6,C5orf42,CEP290,CRLF1,CTNNBIP1,DCHS2,DLG5,ENPEP,EPHA4,EYA1,FAT4,FBN1,FGF8,FOXD1,FRAS1,GATA3,GCNT1,GCNT3,GLI2,GLI3,GLIS2,HNF1B,HOXA11,HOXC11,HOXD11,HYAL2,IRX1,IRX2,IRX3,JAG1,KCNJ8,LAMB2,LHX1,LZTS2,MEF2C,MMP17,MYO1E,NF1,NID1,NIPBL,NOTCH1,NPHP3,NPNT,NUP93,OSR2,PAX2,PCSK5,PCSK9,PDGFRA,PGF,PKD1,PKD2,PLCE1,POU3F3,PPAT,PROX1,PTCH1,PYGO1,RARB,RIDA,RPGRIP1L,RRM2B,SALL1,SDC1,SERPINF1,SHH,SIM1,SIX1,SIX2,SIX4,SMAD1,SMAD3,SMAD6,SMAD9,STAT1,SULF1,SULF2,TFAP2A,TNS2,TP73,TSC1,WDPCP,WT1	MammalFishAncestor	114.264
GO.Biological.Process	GO:0045444	fat.cell.differentiation	201	4.882087e-119	6.306192e-115	3.137409e-117	1.838196e+0	ADRB1,ANGPTL8,ATF2,BBS2,CEBPD,CTBP2,EP300,FBXO9,FFAR4,GPX1,ITGA6,LRRC8C,MED1,MKKS,NIPBL,NOC3L,NR4A2,NR4A3,OSBPL8,PIAS1,PLAC8,PPARG,PRDM16,PSMB8,PTGS2,SLC2A4,SMAD6,SREBF1,TCF7L2,TMEM120B,WNT5B,ZNF516	MammalFishAncestor	114.2
GO.Biological.Process	GO:0042692	muscle.cell.differentiation	202	5.917680e-119	7.643867e-115	3.784093e-117	1.508895e+0	ACTA1,ACTC1,ACTG1,ACVR1,ADAM12,ADGRB3,ADM,AKT1,ANK2,ARID1A,ASB2,ATP2A2,AXIN1,BCL9,CAPN3,CASQ1,CHRNB1,DNER,DTYMK,EDNRB,FLNC,GATA6,GLMN,GPX1,H3F3B,HMGCR,HOMER1,JAG1,KAT2A,KDM6B,KLHL40,KLHL41,KRT8,LEF1,LMOD2,MAPK12,MEF2C,MTOR,MYBPC1,MYBPC2,MYBPC3,MYBPHL,MYEF2,MYF5,MYF6,MYH11,MYH3,MYL2,MYOM1,MYOM2,MYOZ1,MYOZ2,NEXN,NFATC2,NOS1,NOTCH1,NPNT,NPPA,NPPB,OBSCN,OBSL1,P2RX2,PDGFRA,PITX1,PITX2,PROX1,PROX2,RARB,RORA,RYR1,SDC1,SGCG,SHH,SIX1,SIX4,SMARCD3,SORT1,SOX6,SPAG9,SPEG,STAC3,SYNE1,TANC1,TBX1,TBX2,TCAP,TCF7L2,TPM1,TRIM54,TSC1,WFIKKN2,WT1	MammalFishAncestor	114.117
GO.Biological.Process	GO:0007632	visual.behavior	203	6.048193e-119	7.812451e-115	3.848498e-117	2.344950e+0	ABCC8,ATP1A2,DRD3,FOXB1,HMGCR,HOXA1,HRH1,KIT,KMT2A,MEIS2,MTOR,NF1,NLGN3,NPS,PIAS1,PPP1R1B,TANC1	MammalFishAncestor	114.107
GO.Biological.Process	GO:0035583	sequestering.of.TGFbeta.in.extracellular.matrix	204	9.184339e-119	1.186341e-114	5.815397e-117	5.752364e+0	FBN1,FBN2,LTBP1	MammalFishAncestor	113.926
GO.Biological.Process	GO:0035270	endocrine.system.development	205	1.768723e-118	2.284659e-114	1.114468e-116	1.683766e+0	AKT1,ALDH1A2,BMP6,CRH,CRKL,DKK3,FGF8,FOXA2,GATA3,GATA6,GLI1,GLI2,GSX1,HOXA3,HOXA5,HOXB3,HOXD3,INSM1,LHX3,MAP2K1,MDK,MEN1,MNX1,NEUROG3,NF1,NKX2-1,NKX2-2,NKX6-1,NKX6-2,NR5A1,ONECUT1,ONECUT2,OTP,PAX1,PAX6,PDGFRA,PDX1,PITX1,PITX2,POU3F2,RAF1,SALL1,SHH,SIX1,SIX3,SLC6A3,SMAD3,SOX2,TBX1,WT1	MammalFishAncestor	113.641
GO.Biological.Process	GO:0021912	regulation.of.transcription.from.RNA.polymerase.II.promoter.involved.in.spinal.cord.motor.neuron.fate.specification	206	2.808818e-118	3.628150e-114	1.761238e-116	6.007273e+0	NKX6-1,NKX6-2,PAX6	MammalFishAncestor	113.44
GO.Biological.Process	GO:2000674	regulation.of.type.B.pancreatic.cell.apoptotic.process	207	1.015566e-117	1.311807e-113	6.337230e-116	4.935148e+0	EIF2S1,PDX1,TCF7L2	MammalFishAncestor	112.882
GO.Biological.Process	GO:1900181	negative.regulation.of.protein.localization.to.nucleus	208	1.244559e-117	1.607597e-113	7.728831e-116	2.115698e+0	CCDC22,CYLD,DACT3,DCLK1,DCLK2,EMD,GAS6,GSK3B,KEAP1,LZTS2,MDFIC,MTOR,MXI1,NF1,NFKBIA,NFKBIE,NOV,PKD1,PKD2,PPM1A,PPM1B,RAB23,SIN3A,SRI,TMSB4X	MammalFishAncestor	112.794
GO.Biological.Process	GO:0072001	renal.system.development	209	1.947274e-117	2.515294e-113	1.203490e-115	1.429790e+0	ACAT1,ADAMTS16,AGTR1,ALDH1A2,ARG2,BMP6,C5orf42,CEP290,COL4A1,CRLF1,CTNNBIP1,DCHS2,DLG5,EMX2,ENPEP,EPHA4,EYA1,FAT4,FBN1,FGF8,FOXD1,FRAS1,GATA3,GCNT1,GCNT3,GLI2,GLI3,GLIS2,HNF1B,HOXA11,HOXC11,HOXD11,HYAL2,IRX1,IRX2,IRX3,ITGA6,ITGB4,JAG1,KCNJ8,LAMB2,LHX1,LZTS2,MEF2C,MMP17,MYO1E,NF1,NID1,NIPBL,NOTCH1,NPHP3,NPNT,NUP93,OSR2,PAX2,PCSK5,PCSK9,PDGFRA,PGF,PKD1,PKD2,PLCE1,POU3F3,PPAT,PROX1,PTCH1,PYGO1,RARB,RBP4,RIDA,RPGRIP1L,RRM2B,SALL1,SDC1,SEC63,SERPINF1,SHH,SIM1,SIX1,SIX2,SIX4,SMAD1,SMAD3,SMAD6,SMAD9,STAT1,SULF1,SULF2,TFAP2A,TNS2,TP73,TSC1,WDPCP,WT1	MammalFishAncestor	112.599
GO.Biological.Process	GO:0048665	neuron.fate.specification	210	5.686942e-117	7.345823e-113	3.498011e-115	2.185662e+0	DBX1,DMRT3,EVX1,EYA1,GLI2,GLI3,GSX2,HOXC10,HOXD10,ISL2,LHX3,MNX1,MYT1L,NKX2-2,NKX6-1,NKX6-2,PAX6,POU3F2,POU4F1,SIX1	MammalFishAncestor	112.134
GO.Biological.Process	GO:0032602	chemokine.production	211	6.519767e-116	8.421583e-112	3.991272e-114	5.916083e+0	F2RL1,FOXP1,MCOLN2,TUSC2	MammalFishAncestor	111.075
GO.Biological.Process	GO:0070925	organelle.assembly	212	8.146333e-116	1.052262e-111	4.963499e-114	1.405886e+0	ABCC4,ABRAXAS2,ACTA1,ACTC1,ACTG1,AGFG1,AKAP9,AMBRA1,ARHGEF10,ARMC4,ATG4B,ATG4C,ATG7,ATP6V1D,BBIP1,BBS10,BBS2,BBS5,BCCIP,BIN2,C5orf42,CAPN3,CASQ1,CC2D2A,CCDC136,CCDC39,CCDC63,CCNO,CEP131,CEP135,CEP152,CEP164,CEP192,CEP290,CEP76,CFAP46,CFAP74,CIRBP,CLASP1,CNOT7,CSNK1D,DCTN2,DDX3X,DDX6,DNAAF4,DNAH1,DNAH5,DNAH7,DNAH8,DRC1,DYNC1H1,DYNC1I2,DYNC2H1,DYNC2LI1,DZIP1,ENSG00000248710,ENSG00000251569,FAM161A,FARP2,FBF1,FLNA,FOPNL,GABARAP,GALNT11,HAUS1,HSP90AA1,ICK,IFT122,IFT43,IFT80,IFT81,IFT88,INO80,IQUB,KIF17,KIF23,KIF3A,KIF3B,KIF3C,KLHL41,KRT8,LMOD2,LSM14A,LSM4,MARK4,MDN1,MFN2,MKKS,MPV17L2,MYBPC1,MYBPC2,MYBPC3,MYBPHL,MYH11,MYH3,MYL2,MYO7A,MYOM1,MYOM2,MYOZ1,MYOZ2,MZT1,NCOR1,NDE1,NEK1,NEK2,NEK6,NEK7,NEURL1,NLGN2,NOP2,NOTCH1,NPHP3,NRXN1,NUMA1,OBSCN,OBSL1,ODF2,OFD1,OGFOD1,ONECUT1,ONECUT2,PARVA,PDGFRA,PIBF1,PPAN,PPAN-P2RY11,PROX1,PTPN23,PUM2,RAB11A,RAB20,RAB23,RAB32,RABL2B,RB1CC1,RFX4,RHOA,RILP,RILPL1,RILPL2,RPF1,RPF2,RPGRIP1L,RPL10,RPL3L,RPL5,RPS10,RPS15,RPS27L,RRS1,RSL24D1,SDCCAG8,SEPT2,SH3PXD2A,SIX4,SNAP29,SNF8,SPAG1,SPAG17,SPICE1,SSX2IP,STAM2,STX17,SYNPO2,TCAP,TCTN1,TCTN2,TEKT2,TMEM67,TMF1,TNPO1,TPM1,TRIM59,TTC21B,TTC30A,TTC30B,TTC8,TTLL5,TUBA4A,TUBB4B,TUBG1,TUBGCP4,TUBGCP5,TUBGCP6,TXNDC8,UBE2B,UBXN2A,VIL1,VPS37A,VPS37B,WASHC1,WDPCP,WDR19,WDR34,WRAP73,ZMYND10,ZNF207	MammalFishAncestor	110.978
GO.Biological.Process	GO:0045104	intermediate.filament.cytoskeleton.organization	213	1.376586e-115	1.778136e-111	8.348057e-114	2.854024e+0	AGFG1,DES,DNAJB6,DST,EPPK1,ERBIN,INA,KRT18,KRT3,NDEL1,PKP1,RAF1,SHH,VPS54	MammalFishAncestor	110.75
GO.Biological.Process	GO:0048663	neuron.fate.commitment	214	4.086214e-115	5.278163e-111	2.466431e-113	1.836694e+0	AXIN1,DBX1,DLL4,DLX1,DLX2,DMRT3,EVX1,EYA1,FOXN4,GLI2,GLI3,GSX1,GSX2,HOXC10,HOXD10,ID2,ISL2,LHX3,MNX1,MYT1L,NKX2-1,NKX2-2,NKX6-1,NKX6-2,NOTCH1,PAX6,POU3F2,POU4F1,SHH,SIX1,TBR1,ZNF521	MammalFishAncestor	110.278
GO.Biological.Process	GO:0006921	cellular.component.disassembly.involved.in.execution.phase.of.apoptosis	215	6.456669e-115	8.340079e-111	3.879107e-113	4.231927e+0	ACVR1C,BOK,CDK5RAP3,DICER1,DNASE1L3,DNASE2B,ENDOG,FOXL2	MammalFishAncestor	110.079
GO.Biological.Process	GO:0035194	posttranscriptional.gene.silencing.by.RNA	216	1.257001e-114	1.623668e-110	7.516982e-113	2.745745e+0	AGO1,AGO3,AGO4,CNOT7,DGCR8,DHX9,DICER1,PRKRA,PUM1,PUM2,RAN,SMAD1,SMAD3,STAT3,TNRC6A,ZC3H7B	MammalFishAncestor	109.79
GO.Biological.Process	GO:0042093	T-helper.cell.differentiation	217	1.907020e-114	2.463298e-110	1.135160e-112	3.016319e+0	ATP7A,BATF,FOXP1,GATA3,LEF1,RORA,STAT3	MammalFishAncestor	109.608
GO.Biological.Process	GO:1904339	negative.regulation.of.dopaminergic.neuron.differentiation	218	3.610008e-114	4.663047e-110	2.139013e-112	6.315394e+0	GSK3B,SHH	MammalFishAncestor	109.331
GO.Biological.Process	GO:0045103	intermediate.filament-based.process	219	4.362116e-114	5.634545e-110	2.572852e-112	2.830817e+0	AGFG1,DES,DNAJB6,DST,EPPK1,ERBIN,INA,KRT18,KRT3,NDEL1,PKP1,RAF1,SHH,VPS54	MammalFishAncestor	109.249
GO.Biological.Process	GO:0007016	cytoskeletal.anchoring.at.plasma.membrane	220	6.406896e-114	8.275788e-110	3.761722e-112	4.442827e+0	ANK3,DAG1,FLNB,JUP,SHANK1,SPTBN4,TLN2	MammalFishAncestor	109.082
GO.Biological.Process	GO:0061470	T.follicular.helper.cell.differentiation	221	2.027557e-113	2.618995e-109	1.185066e-111	6.476363e+0	FOXP1	MammalFishAncestor	108.582
GO.Biological.Process	GO:0010172	embryonic.body.morphogenesis	222	9.025158e-113	1.165780e-108	5.251260e-111	4.632155e+0	IFT122,MAB21L2,ZNF281	MammalFishAncestor	107.933
GO.Biological.Process	GO:0043066	negative.regulation.of.apoptotic.process	223	1.051445e-112	1.358152e-108	6.090366e-111	1.297798e+0	AATF,ACTC1,ACVR1,AGO4,AKT1,AMBRA1,ANKLE2,AREL1,ARF4,ARG2,ARHGAP10,AVEN,AZU1,BAG3,BAG5,BARHL1,BCL2L10,BIRC6,BIRC7,BNIP2,BOK,C5AR1,CAPN3,CD40LG,CLDN7,COL2A1,COMP,COPS5,CRLF1,CSF2,CTTN,DDX3X,DHCR24,DLX1,DNAJB6,DNAJC3,DNAJC5,DOCK8,EDNRB,EIF5A,EN2,ENO1,ERBB3,ERC1,EVI2B,EYA1,F2R,FAIM,FANK1,FASLG,FFAR4,FGA,FGB,FGF20,FGF8,FGG,FKBP8,FLNA,FNIP1,FOXB1,FOXP1,FYN,GABRB2,GAS6,GATA3,GATA6,GCG,GCLC,GCLM,GLI2,GLI3,GPI,GPX1,GSK3B,HCK,HHIP,HIP1R,HIPK3,HMGCR,HNF1B,HTATIP2,HTT,ICAM1,IRS2,ITGA6,IVNS1ABP,KDM2B,KDR,KIF14,KITLG,KRT18,LAMTOR5,LEF1,LHX3,LHX4,LRP1,MAP2K5,MAPK8,MCL1,MDK,MED1,MEF2C,MEIS3,MGMT,MNAT1,MT3,MTOR,MYD88,MYO18A,NAA38,NDUFA13,NFE2L2,NFKBIA,NOD2,NONO,NOTCH1,NR2E1,NR4A2,NR4A3,OXR1,PA2G4,PAK5,PAX2,PDCD4,PDK4,PDX1,PHB2,PIAS1,PIM3,PLAC8,POU3F3,POU4F1,PRKCA,PRKCD,PRKCQ,PRKCZ,PRKDC,PROK2,PSMG2,PTGFR,PTGS2,PTRH2,QARS,RAF1,RARB,RASA1,RB1CC1,RNF34,ROCK1,RPL10,RPS3A,RPS6KB1,RRM2B,SELENOS,SET,SFN,SFRP2,SH3RF1,SHH,SIN3A,SIX1,SIX4,SLC39A10,SMAD3,SMAD6,SPHK1,STAT3,STAT5B,STK40,SUPV3L1,TAX1BP1,TBX1,TCF7,TCF7L2,TFAP2A,TGFB3,TIAF1,TMEM161A,TMF1,TNFAIP8,TNFRSF6B,TOX3,TP73,TRAP1,TXNDC12,TXNDC5,TYRO3,UBA52,UBB,UBE2B,UCN,UFM1,UNG,URI1,USP47,VDAC2,VIL1,WNK3,WNT7A,WT1,YWHAZ,ZMYND11,ZNF304	MammalFishAncestor	107.867
GO.Biological.Process	GO:0033627	cell.adhesion.mediated.by.integrin	224	1.515479e-112	1.957544e-108	8.739037e-111	3.779331e+0	ADAM17,FBN1,ICAM1,ITGA6,ITGB6,NOV,NPNT	MammalFishAncestor	107.708
GO.Biological.Process	GO:0048870	cell.motility	225	1.648684e-112	2.129605e-108	9.464912e-111	1.259312e+0	ABCC1,ACVR1,ADAM17,AGTR1,AIMP1,ANKS1A,APCDD1,APOB,ARF4,ARHGEF16,ARPC5L,ARSB,ARX,ATP1A4,ATP5B,AUTS2,AZU1,BAMBI,BARHL1,BARHL2,BBS2,BIN2,C16orf45,C5AR1,CALCA,CATSPER3,CCDC39,CCL20,CD248,CDKL5,CENPV,CFAP44,CFAP46,CHGA,COL1A1,COL1A2,CORO1C,CSF3R,CSPG4,CTHRC1,CTTN,CXCR5,CYP7B1,DAPK2,DCLK1,DGKZ,DMRT1,DNAAF4,DNAH1,DNAH11,DNAH2,DNAH5,DNAH7,DNAH8,DNER,DOCK1,DOCK4,DOCK8,DPCD,DPP4,DRC1,DRGX,DST,EDNRB,ELANE,EMX2,ENPEP,ENPP2,EPHA4,F2RL1,FAP,FAT2,FEZF1,FGF8,FLNA,FLT1,FN1,FOLR1,FOXB1,FSCN1,FSCN2,FYN,GAS6,GATA3,GBF1,GCNT1,GLI3,GPX1,GRB14,GYPA,GYPB,HCK,HEXB,HOXA5,HOXB9,HRH1,ICAM1,IER2,ITGA6,ITGB1BP1,ITGB4,JAK1,JMY,JUP,KALRN,KDR,KIT,KITLG,LAMB1,LAMC1,LEF1,LHX1,LRP12,LURAP1,LYST,MAP2K1,MATN2,MCOLN2,MDK,MEF2C,MEGF8,MYO18A,NAV1,NDE1,NDEL1,NEURL1,NFATC2,NKX2-1,NKX6-1,NODAL,NOTCH1,NOV,NOX1,NR2E1,NR2F2,NR4A2,NRCAM,NTN1,NUP188,NUP93,OGDH,P2RY12,PAK5,PAK6,PALLD,PARVA,PAX6,PDGFRA,PHOX2B,PIK3CB,PIK3CD,PIK3R2,PITX2,PKN2,PKN3,PLCG1,PLPP1,PLXNB3,PLXND1,POU3F2,POU3F3,POU4F1,PPIA,PPP1R9B,PREX1,PRKCD,PRKCQ,PRKCZ,PROX1,PRTN3,PSTPIP2,PTK6,PTPN6,PTPRF,RAPGEF2,RELN,RERE,RHOA,ROCK1,RPS6KB1,RTN4,SDC1,SDC3,SDCCAG8,SELPLG,SEMA3F,SETD2,SHH,SHTN1,SIX1,SIX2,SIX3,SIX4,SLC16A3,SLC22A16,SOX18,SPEM1,SPNS2,STARD13,STAT5B,TBX1,TBX21,TEKT2,TGFBR3,THBS4,TMEM201,TMF1,TNFRSF11A,TNFSF11,TNFSF12,TNK1,TOP2B,TSPAN1,TTLL5,TYK2,TYRO3,UBE2B,UNK,USP33,USP9X,USP9Y,VAX1,VIL1,WDPCP,WNT7A,WWC1,ZEB2,ZRANB1	MammalFishAncestor	107.672
GO.Biological.Process	GO:0051899	membrane.depolarization	226	2.985819e-112	3.856782e-108	1.706541e-110	2.219079e+0	ANK2,ATP1A2,CACNA1A,CACNA1B,CACNA1C,CACNA1D,CACNA1F,CACNA1G,CACNA2D1,CACNB3,CACNB4,CACNG4,CATSPER3,CHRNA4,KMT2A,NALCN,PRKCZ,SCN10A,SCN11A,SCN1A,SCN2A,SCN3A,SCN5A,SCN7A,SCN8A,SCN9A	MammalFishAncestor	107.414
GO.Biological.Process	GO:0097324	melanocyte.migration	227	3.516661e-112	4.542471e-108	2.001089e-110	5.607905e+0	KIT,ZEB2	MammalFishAncestor	107.343
GO.Biological.Process	GO:0016441	posttranscriptional.gene.silencing	228	3.529527e-112	4.559090e-108	1.999601e-110	2.710581e+0	AGO1,AGO3,AGO4,CNOT7,DGCR8,DHX9,DICER1,PRKRA,PUM1,PUM2,RAN,SMAD1,SMAD3,STAT3,TNRC6A,ZC3H7B	MammalFishAncestor	107.341
GO.Biological.Process	GO:0060538	skeletal.muscle.organ.development	229	1.182390e-111	1.527293e-107	6.669402e-110	1.799037e+0	ACTA1,ASB2,BCL9,BCL9L,CASQ1,CHRNA1,COL19A1,COPS2,DNER,EMD,EP300,FLNB,FOS,FOXL2,FOXN2,FOXP2,GPX1,GTF3C5,HOMER1,HOXD10,HOXD9,KLF5,KLHL40,KLHL41,MEF2C,MSC,MYF5,MYF6,MYL6B,MYOM1,MYOM2,NEURL1,NF1,NOTCH1,NR2F2,P2RX2,PHOX2B,PITX1,PITX2,RYR1,SIX1,SIX4,SRPK3,STAC3,TAZ,VAX1,WT1,ZBTB18	MammalFishAncestor	106.816
GO.Biological.Process	GO:0009952	anterior/posterior.pattern.specification	230	1.429593e-111	1.846605e-107	8.028719e-110	1.583061e+0	ABI1,ACVR2A,ALDH1A2,ATM,AXIN1,BPTF,CDX2,CELSR2,CRKL,CTNNBIP1,DDIT3,EMX2,EP300,FEZF1,FGF8,FOXA2,FOXB1,GLI2,GLI3,HNF1B,HOXA10,HOXA11,HOXA3,HOXA5,HOXA6,HOXA7,HOXB1,HOXB2,HOXB3,HOXB4,HOXB5,HOXB6,HOXB7,HOXB8,HOXB9,HOXC10,HOXC11,HOXC13,HOXC4,HOXC5,HOXC6,HOXC8,HOXC9,HOXD10,HOXD13,HOXD3,HOXD4,HOXD8,HOXD9,KAT2A,KDM2B,KMT2A,LDB1,LEF1,LHX1,MED12,MIB1,MYF5,MYF6,NODAL,NOTCH1,NR2F2,NRARP,OTX1,OTX2,PAX1,PAX6,PBX3,PCSK5,POFUT1,PRKDC,SFRP2,SHH,SIX2,SIX3,SMAD3,TBX1,TCAP,TSHZ1,WT1,ZEB2	MammalFishAncestor	106.734
GO.Biological.Process	GO:0072078	nephron.tubule.morphogenesis	231	1.522254e-111	1.966295e-107	8.512102e-110	1.830920e+0	ADAMTS16,CTNNBIP1,EYA1,FAT4,FGF8,FOXD1,GATA3,GLI3,HNF1B,HOXA11,HOXD11,IRX1,IRX2,IRX3,LHX1,NPNT,PAX2,PGF,PKD1,PKD2,PTCH1,SALL1,SHH,SIX1,WT1	MammalFishAncestor	106.706
GO.Biological.Process	GO:0072080	nephron.tubule.development	232	2.266171e-111	2.927213e-107	1.261730e-109	1.747805e+0	ACAT1,ADAMTS16,CTNNBIP1,EYA1,FAT4,FGF8,FOXD1,GATA3,GLI3,HNF1B,HOXA11,HOXD11,IRX1,IRX2,IRX3,JAG1,LHX1,MEF2C,NOTCH1,NPNT,PAX2,PGF,PKD1,PKD2,POU3F3,PTCH1,SALL1,SHH,SIX1,WT1	MammalFishAncestor	106.534
GO.Biological.Process	GO:0060548	negative.regulation.of.cell.death	233	2.444380e-111	3.157406e-107	1.355110e-109	1.278467e+0	AATF,ABCB4,ACTC1,ACVR1,AGO4,AKT1,AMBRA1,ANKLE2,AREL1,ARF4,ARG2,ARHGAP10,ATG7,AVEN,AZU1,BAG3,BAG5,BARHL1,BCL2L10,BIRC6,BIRC7,BNIP2,BOK,C5AR1,CAPN3,CD40LG,CHGA,CLDN7,COL2A1,COMP,COPS5,CRH,CRLF1,CSF2,CTTN,DDX3X,DHCR24,DLX1,DNAJA3,DNAJB6,DNAJC3,DNAJC5,DOCK8,EDNRB,EIF4G1,EIF5A,EN2,ENO1,ERBB3,ERC1,EVI2B,EYA1,F2R,FAIM,FANK1,FASLG,FFAR4,FGA,FGB,FGF20,FGF8,FGG,FKBP8,FLNA,FNIP1,FOXB1,FOXP1,FYN,GABRB2,GAS6,GATA3,GATA6,GCG,GCLC,GCLM,GLI2,GLI3,GPI,GPX1,GSK3B,HCK,HHIP,HIP1R,HIPK3,HMGCR,HNF1B,HTATIP2,HTT,ICAM1,IMPACT,IRS2,ITGA6,IVNS1ABP,KANK2,KDM2B,KDM4A,KDR,KIF14,KIT,KITLG,KRT18,LAMTOR5,LEF1,LHX3,LHX4,LRP1,LRPAP1,MAP2K5,MAPK8,MCL1,MDK,MECOM,MED1,MEF2C,MEIS3,MET,MGMT,MNAT1,MT3,MTOR,MYD88,MYO18A,NAA38,NDUFA13,NFE2L2,NFKBIA,NOD2,NONO,NOTCH1,NOV,NR2E1,NR4A2,NR4A3,NUP93,OXR1,PA2G4,PAK5,PAX2,PDCD4,PDE12,PDK4,PDX1,PHB2,PIAS1,PIM3,PLAC8,POU3F3,POU4F1,PRKCA,PRKCD,PRKCQ,PRKCZ,PRKDC,PROK2,PSMG2,PTGFR,PTGS2,PTRH2,QARS,RAF1,RARB,RASA1,RB1CC1,RNF34,ROCK1,RPL10,RPS3A,RPS6KB1,RRM2B,SELENOS,SERPINF1,SET,SFN,SFRP2,SH3RF1,SHH,SIN3A,SIX1,SIX4,SLC25A4,SLC39A10,SMAD3,SMAD6,SPHK1,STAT3,STAT5B,STK40,SUPV3L1,TAX1BP1,TBX1,TCF7,TCF7L2,TFAP2A,TGFB3,TIAF1,TMEM161A,TMEM259,TMF1,TNFAIP8,TNFRSF6B,TOX3,TP73,TRAP1,TSC1,TXNDC12,TXNDC5,TYRO3,UBA52,UBB,UBE2B,UCN,UFM1,UNG,URI1,USP47,VDAC2,VIL1,WISP3,WNK3,WNT7A,WT1,YWHAZ,ZFPM2,ZMYND11,ZNF304	MammalFishAncestor	106.501
GO.Biological.Process	GO:0051176	positive.regulation.of.sulfur.metabolic.process	234	4.292473e-111	5.544587e-107	2.369482e-109	4.591091e+0	COMT,NFE2L2,TCF7L2	MammalFishAncestor	106.256
GO.Biological.Process	GO:0007517	muscle.organ.development	235	1.230653e-110	1.589634e-106	6.764402e-109	1.468633e+0	ACTA1,ACTC1,ASB2,BCL9,BCL9L,CAPN3,CASQ1,CHRNA1,COL11A1,COL19A1,COPS2,DLL4,DNER,EMD,EP300,FHL1,FHL3,FLNB,FOS,FOXK1,FOXL2,FOXN2,FOXP2,FXR1,GPX1,GSC,GTF3C5,HOMER1,HOXD10,HOXD9,ITGB1BP2,KLF5,KLHL40,KLHL41,LAMA2,LRP2,MAPK12,MED1,MEF2B,MEF2C,MKX,MSC,MYBPC3,MYF5,MYF6,MYH3,MYL2,MYL6B,MYOM1,MYOM2,NEB,NEURL1,NF1,NOTCH1,NR2F2,P2RX2,PAX3,PHOX2B,PITX1,PITX2,POU4F1,POU6F1,PROX1,RYR1,RYR2,SGCA,SGCE,SGCG,SHOX2,SIX1,SIX4,SOX6,SPEG,SRI,SRPK3,STAC3,TAZ,TBX1,TCAP,TCF12,TGFBR3,TNNC1,TNNI1,TNNT2,TPM1,UBE4B,UTRN,VAX1,WNT2,WT1,XIRP2,ZBTB18,ZBTB42,ZFHX3,ZFPM2	MammalFishAncestor	105.799
GO.Biological.Process	GO:0014037	Schwann.cell.differentiation	236	1.761055e-110	2.274755e-106	9.638791e-109	2.783143e+0	ADAM22,AKT1,ARHGEF10,CNTNAP1,DAG1,DICER1,ERBB3,LAMA2,LAMB2,MED12,MPP5,MYOC,NAB1,NF1,PARD3,POU3F1,POU3F2	MammalFishAncestor	105.643
GO.Biological.Process	GO:0016579	protein.deubiquitination	237	2.980701e-110	3.850171e-106	1.624545e-108	1.632491e+0	ABRAXAS1,ABRAXAS2,ACTB,ACTL6A,ASXL1,ASXL2,ATXN3L,ATXN7,ATXN7L3,AXIN1,BAP1,CCNA1,CFTR,CLSPN,COPS5,CYLD,ENY2,EP300,ESR1,FOXK1,GATA3,IFIH1,INO80,INO80D,JOSD2,KAT2A,KEAP1,MBD5,MBD6,MINDY2,NFKBIA,NOD2,OGT,OTUB2,OTUD4,OTULIN,PSMA1,PSMA5,PSMA6,PSMA7,PSMB2,PSMB7,PSMB8,PSMB9,PSMD11,PSMD12,PSMD14,PSMD2,PSMD6,RHOA,RHOT1,SENP8,SMAD1,SMAD3,SNX3,STAM2,SUDS3,TADA2B,TOMM20,TRRAP,UBA52,UBB,UCHL3,USP1,USP12,USP13,USP19,USP24,USP30,USP32,USP33,USP35,USP37,USP4,USP42,USP43,USP44,USP45,USP47,USP5,USP53,USP54,USP9X,USP9Y,VCPIP1,WDR20,WDR48,ZRANB1	MammalFishAncestor	105.415
GO.Biological.Process	GO:0060836	lymphatic.endothelial.cell.differentiation	238	5.271178e-110	6.808781e-106	2.860832e-108	4.311324e+0	NR2F2,PROX1,PROX2,SOX18	MammalFishAncestor	105.167
GO.Biological.Process	GO:0072088	nephron.epithelium.morphogenesis	239	1.264806e-109	1.633750e-105	6.835774e-108	1.814260e+0	ADAMTS16,CTNNBIP1,EYA1,FAT4,FGF8,FOXD1,GATA3,GLI3,HNF1B,HOXA11,HOXD11,IRX1,IRX2,IRX3,LHX1,NPNT,PAX2,PGF,PKD1,PKD2,PTCH1,SALL1,SHH,SIX1,SIX2,WT1	MammalFishAncestor	104.787
GO.Biological.Process	GO:0009165	nucleotide.biosynthetic.process	240	1.561140e-109	2.016525e-105	8.402186e-108	1.750431e+0	ACAT1,ADCY5,ADCY6,ADCY7,ADCY9,ADK,ADM,ADSS,ADSSL1,AK4,AK5,AK8,AK9,AMPD2,AMPD3,APRT,ASPDH,ATIC,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP5S,ATP6V0A1,ATP6V0A2,DCTD,DTYMK,DUT,IMPDH2,NADK,NAXD,NME4,NMNAT1,NMNAT2,NPPA,NPPB,PAICS,PAPSS1,PPAT,PRPS2,PTGS2,RFK,RRM2B,SLC22A13,SLC25A13,SLC35B2,SLC35B3,SLC5A8,STOML2,UCKL1,UCN2,UMPS,UPP2	MammalFishAncestor	104.695
GO.Biological.Process	GO:0048016	inositol.phosphate-mediated.signaling	241	1.656856e-109	2.140161e-105	8.880336e-108	2.893267e+0	HRH1,INPP5A,ITPR1,ITPR2,ITPR3,NFATC1,NFATC2,PLCE1,PPP3CB	MammalFishAncestor	104.67
GO.Biological.Process	GO:0043902	positive.regulation.of.multi-organism.process	242	1.814859e-109	2.344253e-105	9.686997e-108	1.852690e+0	CCNT1,CD4,CNOT7,CTDP1,DDX3X,DHX9,EDNRB,EP300,F2RL1,FAM170B,GAPDH,GLRA1,GTF2B,HACD3,HYAL3,INHBA,LEF1,LHFPL2,MDFIC,MVB12B,NELFB,NELFE,NOTCH1,NR5A2,PABPC1,PDE12,PKN2,POLR2A,POLR2E,POLR2K,PPIA,PPID,PRF1,SMARCA4,SMC3,TAF11,TFAP4,TMEM250,TMPRSS2,TRIM11,VPS37B,ZP4	MammalFishAncestor	104.63
GO.Biological.Process	GO:0046949	fatty-acyl-CoA.biosynthetic.process	243	1.824951e-109	2.357289e-105	9.700779e-108	3.357541e+0	ACACA,ACLY,ACSF3,ACSL1,ACSL3,ACSL5,ACSL6,CBR4,ELOVL3,ELOVL5,FASN,HACD2,SCD5	MammalFishAncestor	104.628
GO.Biological.Process	GO:0006307	DNA.dealkylation.involved.in.DNA.repair	244	2.265098e-109	2.925827e-105	1.199109e-107	4.173888e+0	ALKBH2,ALKBH5,ASCC3,FTO,MGMT	MammalFishAncestor	104.534
GO.Biological.Process	GO:0070646	protein.modification.by.small.protein.removal	245	2.291352e-109	2.959739e-105	1.208057e-107	1.616658e+0	ABRAXAS1,ABRAXAS2,ACTB,ACTL6A,ASXL1,ASXL2,ATXN3L,ATXN7,ATXN7L3,AXIN1,BAP1,CCNA1,CFTR,CLSPN,COPS2,COPS4,COPS5,COPS7A,CYLD,ENY2,EP300,ESR1,FOXK1,GATA3,IFIH1,INO80,INO80D,JOSD2,KAT2A,KEAP1,MBD5,MBD6,MINDY2,NFKBIA,NOD2,OGT,OTUB2,OTUD4,OTULIN,PSMA1,PSMA5,PSMA6,PSMA7,PSMB2,PSMB7,PSMB8,PSMB9,PSMD11,PSMD12,PSMD14,PSMD2,PSMD6,RHOA,RHOT1,SENP1,SENP6,SENP8,SMAD1,SMAD3,SNX3,STAM2,SUDS3,TADA2B,TOMM20,TRRAP,UBA52,UBB,UCHL3,USP1,USP12,USP13,USP19,USP24,USP30,USP32,USP33,USP35,USP37,USP4,USP42,USP43,USP44,USP45,USP47,USP5,USP53,USP54,USP9X,USP9Y,VCPIP1,WDR20,WDR48,ZRANB1	MammalFishAncestor	104.529
GO.Biological.Process	GO:0072028	nephron.morphogenesis	246	2.881567e-109	3.722120e-105	1.513057e-107	1.812277e+0	ADAMTS16,CTNNBIP1,EYA1,FAT4,FGF8,FOXD1,GATA3,GLI3,HNF1B,HOXA11,HOXD11,IRX1,IRX2,IRX3,LHX1,NPNT,PAX2,PGF,PKD1,PKD2,PTCH1,SALL1,SHH,SIX1,SIX2,WT1	MammalFishAncestor	104.429
GO.Biological.Process	GO:0070482	response.to.oxygen.levels	247	3.236740e-109	4.180897e-105	1.692671e-107	1.495271e+0	ABCB4,ADAM17,ADM,AGTRAP,AKT1,ALKBH5,ARNT,ATG7,ATM,ATP6V0A2,ATP6V1A,ATP7A,BRIP1,CBFA2T3,CHRNA4,COL1A1,CPEB2,CUL2,DNMT3A,DPP4,EDNRA,EGLN3,ENDOG,EP300,ERCC2,FOXO3,GATA6,GNB1,HIF1AN,HP1BP3,ICAM1,ITPR1,ITPR2,KCNMA1,MMP2,MT3,MTHFR,MTOR,NF1,NFE2L2,NOS1,NOTCH1,NOX1,NPPA,NPPB,NR4A2,P2RX2,PAK1,PDK1,PDK3,PGF,PGK1,PHB2,PLOD1,POLG,POSTN,PPARG,PRKCB,PSMA1,PSMA5,PSMA6,PSMA7,PSMB2,PSMB7,PSMB8,PSMB9,PSMD11,PSMD12,PSMD14,PSMD2,PSMD6,PTGS2,RAF1,RBX1,RGCC,RORA,RYR1,RYR2,SCAP,SCFD1,SLC2A4,SMAD3,STOX1,TGFB3,TGFBR3,TM9SF4,TSC1,UBA52,UBB,VASN	MammalFishAncestor	104.379
GO.Biological.Process	GO:0031047	gene.silencing.by.RNA	248	3.476685e-109	4.490834e-105	1.810820e-107	2.327883e+0	AGO1,AGO3,AGO4,ASZ1,CNOT7,CNOT9,DGCR8,DHX9,DICER1,HENMT1,PABPC1,PIWIL1,PRKRA,PUM1,PUM2,RAN,SMAD1,SMAD3,STAT3,TDRD1,TNRC6A,ZC3H7B	MammalFishAncestor	104.348
GO.Biological.Process	GO:0072006	nephron.development	249	3.588596e-109	4.635389e-105	1.861602e-107	1.610083e+0	ACAT1,ADAMTS16,CTNNBIP1,DCHS2,ENPEP,EYA1,FAT4,FGF8,FOXD1,GATA3,GLI3,HNF1B,HOXA11,HOXD11,IRX1,IRX2,IRX3,JAG1,LAMB2,LHX1,MEF2C,MYO1E,NID1,NOTCH1,NPNT,NUP93,PAX2,PDGFRA,PGF,PKD1,PKD2,PLCE1,POU3F3,PTCH1,SALL1,SHH,SIX1,SIX2,SULF1,SULF2,WT1	MammalFishAncestor	104.334
GO.Biological.Process	GO:0032836	glomerular.basement.membrane.development	250	5.602972e-108	7.237359e-104	2.894944e-106	3.892791e+0	LAMB2,MYO1E,NID1,SULF1,SULF2,WT1	MammalFishAncestor	103.14
GO.Biological.Process	GO:0002285	lymphocyte.activation.involved.in.immune.response	251	7.691160e-108	9.934671e-104	3.958036e-106	2.023636e+0	APBB1IP,ATP7A,BATF,CD180,CD40LG,CDH17,EIF2AK4,F2RL1,FOXP1,GATA3,ICAM1,LEF1,MSH6,PLCL2,RAB27A,RORA,STAT3,SWAP70,TSC1,UNC13D	MammalFishAncestor	103.003
GO.Biological.Process	GO:0060322	head.development	252	2.869197e-107	3.706142e-103	1.470691e-105	1.258003e+0	ABCB4,ACAT1,ACSL3,ACTB,AK4,AK8,AKT3,ALDH1A2,ALDH1A3,ANKRD11,ANXA3,ARID1A,ARMC4,ARX,ATIC,ATM,ATP7A,ATRX,AXIN1,BAG3,BAIAP2,BARHL1,BBS2,BOK,BPTF,BRCA2,C12orf57,C16orf45,C5AR1,C5orf42,CDK5RAP3,CEP120,CEP290,CHD5,CIC,CLN5,CNP,COL1A1,COL4A1,CRH,CSRNP1,CTTNBP2,DCLK1,DCLK2,DCT,DLG5,DLX1,DLX2,DLX5,DLX6,DNAH5,DOCK7,DPCD,DSCAML1,DYNC2H1,EDNRA,EFNA2,EMX2,EN2,EZH1,FANCC,FAT4,FEZF1,FGF8,FLNA,FOXB1,FOXO3,FOXP2,FYN,FZD6,GDF7,GLI1,GLI2,GLI3,GNAO1,GNB4,GNPAT,GSC,GSK3B,GSX1,GSX2,H3F3B,HERC1,HMX2,HMX3,HNF1B,HNRNPD,HOXB1,HOXB2,HOXB3,HSPG2,HTR5A,IMMP2L,INA,INHBA,IRS2,KAT2A,KDM2B,KDM6B,KIF14,KIF1A,KIF5B,KNDC1,LAMB1,LDB1,LEF1,LHX1,LHX3,LRP1,LRP2,MAP2K1,MAPKAP1,MBP,MDK,MED1,MEN1,METTL14,MKKS,MMP2,MNAT1,MT3,MTOR,MYH3,NAGLU,NDE1,NDEL1,NEURL1,NEUROD2,NEUROG3,NF1,NIPBL,NKX2-1,NKX2-2,NODAL,NOTCH1,NR2E1,NR2F2,NR4A2,NR4A3,OGDH,OSR2,OTP,OTX1,OTX2,PAFAH1B3,PAK1,PAPD4,PAX2,PAX6,PAX9,PDGFRA,PHF8,PHLPP2,PHOX2A,PHOX2B,PITX1,PITX2,PITX3,PLXNB2,POU3F1,POU3F2,POU3F3,POU4F1,POU6F1,PRKDC,PROX1,PTCH1,PTPRG,PTPRS,QARS,RAB18,RAF1,RAPGEF2,RARB,RELN,RERE,RFX4,RHOA,RIDA,RORA,RPGRIP1L,RTN4,RTN4RL1,SALL1,SALL3,SCN5A,SEC16A,SEMA6D,SETD2,SEZ6,SHH,SIX3,SLC38A3,SLC4A10,SLC6A11,SLC6A17,SLC6A3,SLIT1,SMAD1,SMAD9,SOX2,SPHK1,SPTBN2,STXBP3,SUDS3,SYPL2,SYT1,SZT2,TAF1,TBR1,TBX1,TCTN1,TGFB3,TMEM57,TOP2B,TSC1,TTBK1,TTC21B,TWSG1,TYRO3,UNCX,UQCRQ,VAX1,WNT2,WNT2B,WNT7A,XRN2,YWHAQ,ZEB2,ZIC1,ZIC2	MammalFishAncestor	102.431
GO.Biological.Process	GO:0060216	definitive.hemopoiesis	253	5.103061e-107	6.591624e-103	2.605385e-105	3.368129e+0	HOXB3,HOXB4,KMT2A,MEIS1,SP3,TGFBR3,ZFP36L2	MammalFishAncestor	102.181
GO.Biological.Process	GO:0017148	negative.regulation.of.translation	254	4.434123e-106	5.727557e-102	2.254944e-104	1.844157e+0	AGO1,AGO3,AGO4,CIRBP,CNOT7,CNOT9,CPEB2,CPEB3,DDX3X,DGCR8,DICER1,EIF2AK1,EIF2AK4,EIF2S1,EIF4EBP2,EIF4EBP3,ENC1,FXR1,GAPDH,HNRNPD,METTL14,PRKRA,PUM1,PUM2,RAN,RIDA,SMAD1,SMAD3,STAT3,SYNCRIP,TNRC6A,TOB1,TPR,TSC1,UNK,UPF1,ZC3H12D,ZC3H7B,ZFP36L2,ZNF540	MammalFishAncestor	101.242
GO.Biological.Process	GO:0061004	pattern.specification.involved.in.kidney.development	255	5.028572e-106	6.495406e-102	2.547218e-104	3.087887e+0	FOXD1,IRX1,IRX2,IRX3,PAX2	MammalFishAncestor	101.187
GO.Biological.Process	GO:0061074	regulation.of.neural.retina.development	256	5.222851e-106	6.746357e-102	2.635296e-104	5.270311e+0	DLL4,DLX1,DLX2,POU4F2,SIX3	MammalFishAncestor	101.171
GO.Biological.Process	GO:0001937	negative.regulation.of.endothelial.cell.proliferation	257	7.762167e-106	1.002639e-101	3.901319e-104	2.564870e+0	AIMP1,ATP5A1,DLL4,NF1,NR2F2,RGCC,SPARC,STAT1,SULF1,VASH1	MammalFishAncestor	100.999
GO.Biological.Process	GO:0001666	response.to.hypoxia	258	8.311506e-106	1.073597e-101	4.161230e-104	1.505169e+0	ABCB4,ADAM17,ADM,AGTRAP,AKT1,ALKBH5,ARNT,ATM,ATP7A,BRIP1,CBFA2T3,CHRNA4,CPEB2,CUL2,DNMT3A,DPP4,EDNRA,EGLN3,ENDOG,EP300,ERCC2,FOXO3,GATA6,GNB1,HIF1AN,HP1BP3,ICAM1,ITPR1,ITPR2,KCNMA1,MMP2,MT3,MTHFR,MTOR,NF1,NFE2L2,NOS1,NOTCH1,NPPA,NPPB,NR4A2,P2RX2,PAK1,PDK1,PDK3,PGF,PGK1,PHB2,PLOD1,POSTN,PRKCB,PSMA1,PSMA5,PSMA6,PSMA7,PSMB2,PSMB7,PSMB8,PSMB9,PSMD11,PSMD12,PSMD14,PSMD2,PSMD6,PTGS2,RAF1,RBX1,RGCC,RORA,RYR1,RYR2,SCAP,SCFD1,SLC2A4,SMAD3,STOX1,TGFB3,TGFBR3,TM9SF4,UBA52,UBB,VASN	MammalFishAncestor	100.969
GO.Biological.Process	GO:0001701	in.utero.embryonic.development	259	1.411958e-105	1.823826e-101	7.041800e-104	1.463679e+0	ACVR1,ADAM10,ADM,AKT1,ANKRD11,APOB,ARNT,ATP7A,BIRC6,BPTF,BRCA2,BTF3,CCNB2,CDX2,COL4A3BP,CSF2,CTR9,CUL4A,DNAJB6,EDNRA,ELL,ENDOG,ERCC2,FOXD3,GATA3,GATA6,GCM1,GLI2,GLI3,GPI,HNF1B,HORMAD1,KAT2A,KEAP1,KIDINS220,KRT8,LEF1,LMX1B,MAP2K1,MED1,MFN2,MIB1,MYO1E,NDEL1,NEK2,NODAL,NOTCH1,NR2F2,PDGFRA,PITX2,PKD1,PKD2,PLCD1,PLCG1,PRDM14,PTCH1,RBBP6,RCN1,RESP18,RPGRIP1L,SALL4,SEC24C,SEC24D,SETD2,SF3B6,SIN3A,SLC30A1,SLC39A1,SMAD3,SOX18,SOX6,SP3,STK3,SYF2,TCTN1,TET1,TGFB3,THOC2,TPM1,UBE2B,UBR3,VASH1,WDR19,WNT2,ZFPM2,ZNF568	MammalFishAncestor	100.739
GO.Biological.Process	GO:0071694	maintenance.of.protein.location.in.extracellular.region	260	1.642993e-105	2.122254e-101	8.162516e-104	5.056324e+0	FBN1,FBN2,LTBP1	MammalFishAncestor	100.673
GO.Biological.Process	GO:1903902	positive.regulation.of.viral.life.cycle	261	1.783087e-105	2.303213e-101	8.824573e-104	2.153740e+0	CCNT1,CD4,CNOT7,CTDP1,DDX3X,DHX9,EP300,GTF2B,HACD3,LEF1,MDFIC,NELFB,NELFE,NOTCH1,NR5A2,PABPC1,PDE12,PKN2,POLR2A,POLR2E,POLR2K,PPIA,PPID,SMARCA4,SMC3,TAF11,TFAP4,TMPRSS2,TRIM11,VPS37B	MammalFishAncestor	100.638
GO.Biological.Process	GO:0016482	cytosolic.transport	262	2.222274e-105	2.870511e-101	1.095615e-103	1.918721e+0	AKTIP,ANKFY1,AP1G1,ARFRP1,ARL1,CES1,CLN5,CLTC,CORO7,DENND5A,DOPEY1,DOPEY2,ERC1,EVI5,FAM109A,GBF1,GCC2,LAMP1,MON2,PIKFYVE,PTPN23,RAB9A,RILP,SNF8,SNX2,SORT1,SPAG9,STX10,STX8,TBC1D14,TBC1D5,TMEM87A,UBE2O,VPS13A,VPS13C,VPS26A,VPS29,VPS54,VTI1A,VTI1B,WASHC1,WDR81,ZFYVE21	MammalFishAncestor	100.542
GO.Biological.Process	GO:0003205	cardiac.chamber.development	263	6.415891e-105	8.287406e-101	3.151105e-103	1.540718e+0	ACVR1,ANK2,ARID1A,C5orf42,COL11A1,CPE,DHRS3,DLL4,FGF8,GATA3,GATA6,GJA5,JAG1,LMO4,LRP2,LTBP1,MED1,MEF2C,MYBPC3,MYL2,NOTCH1,NPHP3,NRP2,PARVA,PCSK5,PITX2,PLXND1,POU4F1,PROX1,RARB,RBM15,RBP4,RYR2,SALL1,SALL4,SAV1,SCN5A,SFRP2,SHOX2,SMAD6,SMARCD3,TBX1,TBX2,TGFBR3,TNNC1,TNNI1,TNNT2,TPM1,UBE4B,WNT2,XIRP2,ZFPM2	MammalFishAncestor	100.082
GO.Biological.Process	GO:0086010	membrane.depolarization.during.action.potential	264	8.463571e-105	1.093239e-100	4.141059e-103	2.327678e+0	ANK2,ATP1A2,CACNA1A,CACNA1B,CACNA1C,CACNA1D,CACNA1F,CACNA1G,CACNA2D1,CATSPER3,NALCN,SCN10A,SCN11A,SCN1A,SCN2A,SCN3A,SCN5A,SCN7A,SCN8A,SCN9A	MammalFishAncestor	99.9613
GO.Biological.Process	GO:0060290	transdifferentiation	265	1.086144e-104	1.402972e-100	5.294235e-103	5.279505e+0	INSM1,NEUROG3,PDX1,SMAD3	MammalFishAncestor	99.853
GO.Biological.Process	GO:0043254	regulation.of.protein.complex.assembly	266	1.202055e-104	1.552694e-100	5.837197e-103	1.456443e+0	ANKRA2,ARFGEF1,ARHGAP18,ARPC3,ARPC5L,BAIAP2,BAIAP2L1,BBS10,BMF,CAMSAP1,CAMSAP2,CAPZA1,CAPZA2,CDC42EP4,CDH17,CDT1,CLASP1,CLDN7,CLIP1,CSF2,CTNNBIP1,CTTN,CUL4A,CUL4B,CYFIP1,DDX3X,EIF4G1,ERCC2,ESR1,FARP2,FBLIM1,FKBP4,FNIP1,FNIP2,FSCN1,GBP5,GSK3B,HCK,HIP1R,HNF1B,HSP90AA1,ICAM1,ICE1,IDE,IMPACT,INSM1,IQGAP2,JMY,KANK1,KIF14,LDLRAD4,LMO4,LMOD2,MET,MIEF2,MITF,MKKS,MPP7,MTOR,NAV3,NUMA1,PAK1,PEX14,PEX5,PIEZO1,PPM1A,PPP1R9A,PREX1,PRKCD,PRKCZ,PSRC1,RAF1,RASA1,RBX1,RPA1,SENP6,SLAIN2,SLF1,SLF2,SMAD6,SPIRE1,SPTA1,SPTAN1,SPTBN1,SPTBN2,SPTBN4,TAF1,TAF7,TENM1,TMSB4X,TRIM9,ULK1,UNC13B,VDAC2,VIL1,VILL,VPS41,WASF1,WASHC1,WASL,WHAMM,ZNF451	MammalFishAncestor	99.8089
GO.Biological.Process	GO:0035633	maintenance.of.permeability.of.blood-brain.barrier	267	1.759927e-104	2.273298e-100	8.514224e-103	8.134285e+0	ABCB4,MBP,PTGS2	MammalFishAncestor	99.6433
GO.Biological.Process	GO:0061034	olfactory.bulb.mitral.cell.layer.development	268	2.422660e-104	3.129350e-100	1.167668e-102	6.430653e+0	OGDH,SALL1	MammalFishAncestor	99.5045
GO.Biological.Process	GO:1903844	regulation.of.cellular.response.to.transforming.growth.factor.beta.stimulus	269	2.480054e-104	3.203486e-100	1.190887e-102	1.870879e+0	ADAM17,BAMBI,BCL9L,DKK3,DLX1,FBN1,FBN2,FOLR1,LDLRAD4,LTBP1,MEN1,NKX2-1,NPNT,ONECUT1,ONECUT2,PEG10,PPM1A,PRDM16,RNF111,SKOR1,SMAD3,SMAD6,SNX25,STK11,TGFB3,TGFBR3,UBA52,UBB,VASN,WFIKKN2,ZEB1,ZNF451	MammalFishAncestor	99.4944
GO.Biological.Process	GO:0034243	regulation.of.transcription.elongation.from.RNA.polymerase.II.promoter	270	2.732284e-104	3.529291e-100	1.307145e-102	3.912664e+0	AXIN1,CTR9,ELL,NELFB,NELFE,RECQL5,SHH,SUPT6H,ZMYND11	MammalFishAncestor	99.4523
GO.Biological.Process	GO:0006468	protein.phosphorylation	271	5.134735e-104	6.632537e-100	2.447431e-102	1.257743e+0	AATK,ABI1,ACVR1,ACVR1C,ACVR2A,ADAM10,ADCK5,ADORA2B,AKAP9,AKT1,AKT3,ARHGEF6,ATM,AXIN1,BIRC6,BIRC7,BMP2K,BTRC,BUB1B,CAMK2D,CAMKK1,CCNC,CCNE1,CCNH,CCNT1,CD40LG,CDC37,CDC7,CDK11A,CDK11B,CDK12,CDK17,CDK19,CDK3,CDK8,CDKL1,CDKL3,CDKL5,CIT,CLSPN,CRKL,CSF2,CSNK1A1L,CSNK1D,DAPK2,DCLK1,DCLK2,DLG4,DUSP5,EIF2AK1,EIF2AK4,EIF2S1,ENSG00000167524,EPHA4,ERBB3,ERC1,ERCC2,ERCC6,FASTKD1,FGF16,FGF20,FGF5,FGF8,FLT1,FLT3,FNIP2,FYN,GAS6,GDF7,GPS2,GRK1,GRK4,GSK3B,HACD3,HCK,HIPK3,HIPK4,HSP90AA1,ICK,IL12RB1,IL3,IRS2,JAK1,KALRN,KCNH4,KDR,KIT,KITLG,KL,KLB,KSR2,LATS2,LRRK1,MAP2K1,MAP2K5,MAP3K20,MAP4K2,MAP4K5,MAPK10,MAPK11,MAPK12,MAPK8,MARK4,MAST2,MAST4,MBP,MDFIC,MED1,MEF2C,MEN1,MET,MMD2,MNAT1,MOK,MORC3,MT3,MTOR,MYO3A,MYO3B,NEK1,NEK2,NEK6,NEK7,NEK9,NF1,NOD2,NPRL2,OBSCN,OXSR1,PAK1,PAK5,PAK6,PAN3,PAQR3,PDGFRA,PDK1,PDK2,PDK3,PDK4,PEBP1,PELI1,PHKA2,PHKB,PIBF1,PIK3CD,PIK3R4,PIM3,PKD1,PKN2,PKN3,POU4F2,PPM1D,PPP1R1B,PPP3CB,PPP4R1,PRKAB1,PRKACB,PRKCA,PRKCB,PRKCD,PRKCQ,PRKCZ,PRKD2,PRKD3,PRKDC,PRKG2,PRKRA,PSMA1,PSMA5,PSMA6,PSMA7,PSMB2,PSMB7,PSMB8,PSMB9,PSMD11,PSMD12,PSMD14,PSMD2,PSMD6,PTK6,PTPN6,RAF1,RAPGEF2,RASA1,RASA3,RASGRP3,RASGRP4,RBX1,RELN,RHO,RIPK4,ROCK1,ROR1,RPS6KB1,RPS6KC1,RPS6KL1,RSRC1,RUNX3,SGK3,SKP1,SLK,SMAD1,SMAD9,SPAG9,SPEG,SPTA1,SPTAN1,SPTBN1,SPTBN2,SPTBN4,SRMS,SRPK3,STAT5A,STAT5B,STK11,STK24,STK25,STK3,STK32C,STK33,STK39,STK40,TAB2,TAF1,TAOK1,TAOK3,TGFBR3,TLK1,TLR7,TNFSF11,TNIK,TNK1,TOP1,TPR,TRIO,TSSK6,TTBK1,TYK2,TYRO3,UBA52,UBB,ULK1,WEE1,WNK3,ZFP36L2,ZMYM2	MammalFishAncestor	99.1783
GO.Biological.Process	GO:0043124	negative.regulation.of.I-kappaB.kinase/NF-kappaB.signaling	272	1.650700e-103	2.132209e-99	7.839004e-102	2.288048e+0	CCDC22,CYLD,ESR1,MAPKBP1,NFKBIA,NOV,PPM1A,PPM1B,RHOH,RORA,STAT1,TANK,TMSB4X,TRIM59,ZMYND11	MammalFishAncestor	98.6712
GO.Biological.Process	GO:0051270	regulation.of.cellular.component.movement	273	2.436759e-103	3.147562e-99	1.152953e-101	1.250783e+0	ACVR1,ACVR1C,ADAM10,ADAM17,ADAMTS9,ADRA2A,AKAP9,AKT1,ANGPTL3,ANK2,ANXA3,ARHGAP18,ARMC4,ARSB,ATP1A2,ATP2A2,ATP5A1,ATP5B,ATP7A,BBS2,BCAS3,C16orf45,C5AR1,C5AR2,CACNA1C,CAMK2D,CAVIN1,CCAR1,CCDC39,CCL20,CCSAP,CERS2,CLASP1,CLDN7,CLIC4,CMKLR1,CNIH2,COL1A1,CORO1C,CYP19A1,DACH1,DAG1,DAPK2,DIAPH1,DLG5,DLL4,DNAH11,DOCK1,DOCK4,DOCK7,DOCK8,ECM1,ELANE,ELP5,ELP6,ENPP2,EPPK1,ERBB3,F2R,F2RL1,FGF16,FLNA,FLT1,FN1,FOXP1,GAS6,GATA3,GJA5,GSX2,GTPBP4,HMCN2,HOXA7,HYAL1,HYAL2,ICAM1,IGSF10,INPP5F,INSM1,IRS2,ITGA6,ITGB1BP1,JAG1,JUP,KANK1,KDR,KIF14,KIT,KITLG,LAMA2,LAMA3,LAMA4,LAMB1,LAMC2,LAMP1,LDB1,LDLRAD4,LEF1,LMO4,LRIG2,LRP1,MACF1,MAP2K5,MARVELD3,MCTP1,MEGF8,MET,MIIP,MKKS,MTOR,MYBPC3,MYOC,NAV3,NEXN,NF1,NFE2L2,NIPBL,NISCH,NKD1,NKX2-1,NKX6-1,NODAL,NOTCH1,NOV,NR2E1,NR2F2,NRP2,NSMF,NTN1,ONECUT1,ONECUT2,OSBPL8,P2RY12,PAK1,PAX6,PDGFRA,PGAM4,PGF,PIK3CD,PITX2,PKN2,PLCG1,PLXNB2,PLXNB3,PLXND1,POSTN,POU4F2,PPARG,PRDM14,PREX1,PRKCA,PRKD2,PROX1,PTGS2,PTPN23,PTPRG,RAB11A,RAF1,RAPGEF2,RELN,RGCC,RHOA,RHOB,RHOT1,RNF207,RNF41,ROCK1,RPS6KB1,RRAS2,RTN4,RYR2,SASH1,SCAI,SCN5A,SEMA3F,SEMA6D,SERPINF1,SFRP2,SGK3,SHH,SHTN1,SLC26A5,SLK,SMAD3,SPAG9,SPARC,SPHK1,SRI,SSH1,SSX2IP,STARD13,STAT3,STAT5A,STK24,SULF1,SWAP70,TACR2,TBR1,TGFBR3,THBS4,TMEM102,TMSB4X,TNNC1,TNNT2,TPM1,TRPV4,TTLL6,VASH1,VCL,VIL1,WASHC1,WASL,WDPCP,WNT5B,WNT7A,ZNF304	MammalFishAncestor	98.502
GO.Biological.Process	GO:0031076	embryonic.camera-type.eye.development	274	3.948596e-103	5.100401e-99	1.861460e-101	2.243501e+0	ALDH1A2,ALDH1A3,ARID1A,KDM2B,PAX2,PAX6,PITX2,PROX1,SIX3,SP3,TBX2,TFAP2A,WDR19,ZEB1	MammalFishAncestor	98.2924
GO.Biological.Process	GO:0018105	peptidyl-serine.phosphorylation	275	6.536959e-103	8.443790e-99	3.070469e-101	1.672993e+0	AKT1,AKT3,ATM,CAMK2D,CAMKK1,CDC7,CLSPN,CSNK1A1L,CSNK1D,DAPK2,DCLK1,DCLK2,GAS6,GSK3B,HIPK3,HIPK4,LATS2,MAPK12,MAPK8,MAST2,MAST4,MORC3,MTOR,NEK6,PDK3,PKD1,PKN2,PKN3,PPP1R1B,PRKCA,PRKCB,PRKCD,PRKCQ,PRKCZ,PRKD2,PRKDC,PRKG2,SGK3,STK11,STK32C,STK33,STK39,TAF1,TOP1,TTBK1,ULK1	MammalFishAncestor	98.0735
GO.Biological.Process	GO:0048709	oligodendrocyte.differentiation	276	1.564590e-102	2.020981e-98	7.322395e-101	1.975335e+0	BOK,CNP,CNTNAP1,EIF2B2,ERCC2,GLI3,HDAC10,HDAC11,MED12,NKX2-1,NKX2-2,NKX6-1,NKX6-2,NLGN3,NOTCH1,PAX6,PRDM8,PTPRZ1,SHH,SOX6,TENM4,TRPC4,WASF3	MammalFishAncestor	97.6944
GO.Biological.Process	GO:0048706	embryonic.skeletal.system.development	277	2.241305e-102	2.895094e-98	1.045160e-100	1.623965e+0	ACVR2A,ALX3,AXIN1,COL11A1,COL1A1,COL2A1,DLX1,DLX2,DMRT2,DSCAML1,EYA1,GLI3,GSC,HOXA1,HOXA11,HOXA3,HOXA5,HOXA6,HOXA7,HOXB1,HOXB2,HOXB3,HOXB4,HOXB5,HOXB6,HOXB7,HOXB8,HOXB9,HOXC11,HOXC5,HOXC6,HOXC9,HOXD1,HOXD10,HOXD3,HOXD4,HOXD9,HYAL1,IRX5,KIAA1217,LHX1,MED12,MEF2C,MEGF8,MYCN,MYF5,NIPBL,NODAL,OSR2,PCSK5,PDGFRA,RBP4,SETD2,SHH,SHOX2,SIX1,SIX2,SIX4,SLC39A1,SMAD3,SP3,SULF1,SULF2,TBX1,TFAP2A,TGFB3,WDR19,ZEB1	MammalFishAncestor	97.5383
GO.Biological.Process	GO:0001764	neuron.migration	278	3.479907e-102	4.494996e-98	1.616905e-100	1.588618e+0	ARX,AUTS2,BARHL1,BARHL2,CDKL5,DCLK1,DNAAF4,DNER,DRGX,FEZF1,FYN,GAS6,GATA3,LHX1,LRP12,MATN2,MEF2C,NAV1,NDE1,NDEL1,NKX2-1,NKX6-1,NR2F2,NR4A2,NRCAM,NTN1,PAX6,PHOX2B,PITX2,RAPGEF2,RELN,SDCCAG8,TOP2B,UNK,USP9X,VAX1	MammalFishAncestor	97.3473
GO.Biological.Process	GO:0042110	T.cell.activation	279	5.038371e-102	6.508064e-98	2.332639e-100	1.586468e+0	ADAM17,APBB1IP,ATP7A,BATF,CD4,CYLD,DDOST,DLL4,DNAJA3,DOCK8,DPP4,EIF2AK4,F2RL1,FKBP1B,FOXP1,FYN,FZD8,GATA3,GLI3,ICAM1,KIT,LEF1,LEPR,NEDD4,NKAP,PAX1,PIK3CD,PPP3CB,PREX1,PRKDC,PTPN2,RAB27A,RHOH,RORA,SATB1,SHH,SMAD3,SP3,STAT3,STAT5B,STK11,STOML2,TBX21,TCF7,TSC1,WASHC1,ZFP36L2	MammalFishAncestor	97.1865
GO.Biological.Process	GO:0031016	pancreas.development	280	8.605455e-102	1.111567e-97	3.969881e-100	1.773793e+0	AKT1,ALDH1A2,BMP6,CCDC39,CELA1,FOXA2,GATA6,INSM1,MEIS2,MEN1,MNX1,NEUROG3,NKX2-2,NKX6-1,NKX6-2,NPHP3,NR5A2,ONECUT1,ONECUT2,PAX6,PDX1,PPDPF,PROX1,SHH,TCF7L2	MammalFishAncestor	96.9541
GO.Biological.Process	GO:0030262	apoptotic.nuclear.changes	281	1.963550e-101	2.536318e-97	9.026041e-100	4.068137e+0	ACVR1C,CDK5RAP3,DICER1,DNASE1L3,DNASE2B,ENDOG,FOXL2	MammalFishAncestor	96.5958
GO.Biological.Process	GO:0045292	mRNA.cis.splicing,.via.spliceosome	282	2.666886e-101	3.444817e-97	1.221566e-99	4.167211e+0	DDX23,PSIP1,RNF113A,RNF113B,SFSWAP,SNRNP200,SNRPC	MammalFishAncestor	96.4628
GO.Biological.Process	GO:0008366	axon.ensheathment	283	3.800248e-101	4.908780e-97	1.734551e-99	1.884262e+0	ADAM22,AKT1,AMIGO1,ANK2,ARHGEF10,CNTNAP1,DAG1,DHH,DICER1,EIF2B2,ERCC2,FIG4,GNPAT,HEXB,MBP,MPP5,MYO5A,MYOC,NAB1,NF1,NKX6-2,PARD3,PIKFYVE,POU3F1,POU3F2,PRX,SBF2,SCN2A,SCN8A,SERINC5,TENM4,TSC1	MammalFishAncestor	96.309
GO.Biological.Process	GO:0017015	regulation.of.transforming.growth.factor.beta.receptor.signaling.pathway	284	7.191053e-101	9.288683e-97	3.270663e-99	1.857399e+0	ADAM17,BAMBI,BCL9L,DKK3,FBN1,FBN2,FOLR1,LDLRAD4,LTBP1,MEN1,NKX2-1,NPNT,ONECUT1,ONECUT2,PEG10,PPM1A,PRDM16,RNF111,SKOR1,SMAD3,SMAD6,SNX25,STK11,TGFB3,TGFBR3,UBA52,UBB,VASN,WFIKKN2,ZEB1,ZNF451	MammalFishAncestor	96.032
GO.Biological.Process	GO:0034638	phosphatidylcholine.catabolic.process	285	9.651872e-101	1.246732e-96	4.374499e-99	7.420079e+0	ENPP2,LIPC,PNPLA8	MammalFishAncestor	95.9042
GO.Biological.Process	GO:0071593	lymphocyte.aggregation	286	1.396885e-100	1.804356e-96	6.308938e-99	1.580739e+0	ADAM17,APBB1IP,ATP7A,BATF,CD4,CYLD,DDOST,DLL4,DNAJA3,DOCK8,DPP4,EIF2AK4,F2RL1,FKBP1B,FOXP1,FYN,FZD8,GATA3,GLI3,ICAM1,KIT,LEF1,LEPR,NEDD4,NKAP,PAX1,PIK3CD,PPP3CB,PREX1,PRKDC,PTPN2,RAB27A,RHOH,RORA,SATB1,SHH,SMAD3,SP3,STAT3,STAT5B,STK11,STOML2,TBX21,TCF7,TSC1,WASHC1,ZFP36L2	MammalFishAncestor	95.7437
GO.Biological.Process	GO:0018202	peptidyl-histidine.modification	287	2.849204e-100	3.680317e-96	1.282340e-98	4.658919e+0	DNAJC24,DPH1,DPH6,DPH7,HIF1AN	MammalFishAncestor	95.4341
GO.Biological.Process	GO:0007418	ventral.midline.development	288	7.007714e-100	9.051864e-96	3.143008e-98	5.260273e+0	GLI1,GLI2,SHH	MammalFishAncestor	95.0433
GO.Biological.Process	GO:0021938	smoothened.signaling.pathway.involved.in.regulation.of.cerebellar.granule.cell.precursor.cell.proliferation	288	7.007714e-100	9.051864e-96	3.143008e-98	5.260273e+0	GLI1,GLI2,SHH	MammalFishAncestor	95.0433
GO.Biological.Process	GO:0042473	outer.ear.morphogenesis	290	8.554135e-100	1.104938e-95	3.810130e-98	3.715550e+0	EYA1,HOXA1,PRKRA,SALL1,TBX1	MammalFishAncestor	94.9567
GO.Biological.Process	GO:2001233	regulation.of.apoptotic.signaling.pathway	291	9.389438e-100	1.212834e-95	4.167813e-98	1.473734e+0	ACVR1,AKT1,APOPT1,BAG5,BBC3,BCAP31,BCL2L10,BIRC6,BMF,BOK,COL2A1,CSF2,CTTN,CYLD,DAPK2,DDIT3,DDX3X,ENO1,EYA1,FASLG,FGA,FGB,FGG,FYN,GCLC,GCLM,GPX1,GSK3B,HIP1R,HTT,HYAL2,ICAM1,INHBA,ITGA6,IVNS1ABP,MADD,MAP2K5,MAPK8,MCL1,MEIS3,MFF,MOAP1,NACC2,NDUFA13,NF1,NFE2L2,NONO,NOX1,NR4A2,PAK5,PDCD5,PDIA2,PDX1,PLAGL2,PPP1R13B,PRKCD,PRKRA,PTGS2,PTPN2,QARS,RAF1,RB1CC1,RNF34,RPS6KB1,RRM2B,SELENOS,SFN,SFRP2,SH3RF1,SMAD3,ST18,STK3,TCF7L2,TFAP4,TFDP1,TMEM102,TMEM161A,TNFSF12,TP73,TRAP1,TXNDC12,UBB,URI1,USP47,VDAC2,YWHAQ,YWHAZ,ZMYND11	MammalFishAncestor	94.9162
GO.Biological.Process	GO:0060459	left.lung.development	292	9.589581e-100	1.238686e-95	4.242076e-98	5.053773e+0	NODAL,PITX2,SHH	MammalFishAncestor	94.907
GO.Biological.Process	GO:0034329	cell.junction.assembly	293	1.084708e-99	1.401117e-95	4.781970e-98	1.750048e+0	ACTB,ACTG1,ANK2,CAPZA1,CNTNAP1,COL17A1,CTTN,DLG5,FBF1,FBLIM1,FLNA,FLNC,FN1,FSCN1,GJA5,GJB1,GJB2,GNPAT,ITGA6,ITGB4,JUP,LAMA3,LAMC1,LAMC2,LIMS1,MARVELD3,MICALL2,MPP5,MPP7,MYO9A,PARD3,PKN2,PKP4,PLEC,PRKCA,RHOA,STRN,TLN2,TRPV4,VCL,VMP1,WHAMM	MammalFishAncestor	94.8535
GO.Biological.Process	GO:0021527	spinal.cord.association.neuron.differentiation	294	3.537772e-99	4.569740e-95	1.554333e-97	3.587562e+0	GDF7,GSX1,GSX2,LHX1,LHX3,LMO4	MammalFishAncestor	94.3401
GO.Biological.Process	GO:0009142	nucleoside.triphosphate.biosynthetic.process	295	3.975012e-99	5.134523e-95	1.740516e-97	2.604064e+0	ADK,AK4,AK5,AK8,AK9,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP5S,ATP6V0A1,ATP6V0A2,DTYMK,IMPDH2,NME4,SLC25A13,STOML2,UCKL1	MammalFishAncestor	94.2895
GO.Biological.Process	GO:0030217	T.cell.differentiation	296	4.541391e-99	5.866115e-95	1.981796e-97	1.691590e+0	ADAM17,ATP7A,BATF,CD4,CYLD,DLL4,DNAJA3,FOXP1,FZD8,GATA3,GLI3,KIT,LEF1,LEPR,NKAP,PAX1,PIK3CD,PPP3CB,PREX1,PRKDC,PTPN2,RHOH,RORA,SATB1,SHH,SP3,STAT3,STAT5B,STK11,TBX21,TCF7,TSC1,ZFP36L2	MammalFishAncestor	94.2316
GO.Biological.Process	GO:0036293	response.to.decreased.oxygen.levels	297	1.207941e-98	1.560297e-94	5.253527e-97	1.481335e+0	ABCB4,ADAM17,ADM,AGTRAP,AKT1,ALKBH5,ARNT,ATM,ATP7A,BRIP1,CBFA2T3,CHRNA4,CPEB2,CUL2,DNMT3A,DPP4,EDNRA,EGLN3,ENDOG,EP300,ERCC2,FOXO3,GATA6,GNB1,HIF1AN,HP1BP3,ICAM1,ITPR1,ITPR2,KCNMA1,MMP2,MT3,MTHFR,MTOR,NF1,NFE2L2,NOS1,NOTCH1,NPPA,NPPB,NR4A2,P2RX2,PAK1,PDK1,PDK3,PGF,PGK1,PHB2,PLOD1,POSTN,PRKCB,PSMA1,PSMA5,PSMA6,PSMA7,PSMB2,PSMB7,PSMB8,PSMB9,PSMD11,PSMD12,PSMD14,PSMD2,PSMD6,PTGS2,RAF1,RBX1,RGCC,RORA,RYR1,RYR2,SCAP,SCFD1,SLC2A4,SMAD3,STOX1,TGFB3,TGFBR3,TM9SF4,TSC1,UBA52,UBB,VASN	MammalFishAncestor	93.8068
GO.Biological.Process	GO:0010927	cellular.component.assembly.involved.in.morphogenesis	298	1.585177e-98	2.047573e-94	6.871051e-97	1.991154e+0	ACTA1,ACTC1,ACTG1,AGFG1,ANK2,CAPN3,CASQ1,CCDC136,CNTNAP1,DICER1,ERCC2,FIG4,GNPAT,KLHL41,KRT8,LMOD2,MPP5,MYBPC1,MYBPC2,MYBPC3,MYBPHL,MYH11,MYH3,MYL2,MYOM1,MYOM2,MYOZ1,MYOZ2,OBSCN,OBSL1,PDGFRA,PIKFYVE,PROX1,SIX4,TCAP,TENM4,TMF1,TPM1,TXNDC8	MammalFishAncestor	93.6888
GO.Biological.Process	GO:0090662	ATP.hydrolysis.coupled.transmembrane.transport	299	2.304620e-98	2.976878e-94	9.956113e-97	2.338986e+0	ABCB11,ABCC1,ABCC10,ABCC3,ABCC4,ABCC6,ABCC8,ABCC9,ATP13A3,ATP1A2,ATP1A4,ATP2A2,ATP2A3,ATP2C1,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP6V0A1,ATP6V0A2,ATP6V1A,ATP6V1F,ATP7A,CFTR	MammalFishAncestor	93.5262
GO.Biological.Process	GO:0009314	response.to.radiation	300	2.527226e-98	3.264418e-94	1.088139e-96	1.438739e+0	AANAT,ABCA4,ABCC8,ABCG5,ABRAXAS1,AKT1,ATM,ATP1A2,BHLHE40,BMF,BRCA2,CACNA1F,CACNA2D4,CIRBP,CLOCK,CRTC1,CUL4B,CYP2R1,DNMT3A,DRD3,DTL,EIF2AK4,EIF2S1,ELANE,EP300,ERCC2,ERCC6,EYA1,FBXL3,FECH,FOS,FOXB1,GATA3,GJA10,GNAT1,GNAT2,GNB1,GPX1,GRK1,HMGCR,HOXA1,HRH1,HYAL1,HYAL2,HYAL3,ICAM1,ID2,IMPACT,INO80,INTS7,JUND,KIT,KMT2A,LZIC,MAP3K20,MAPK10,MAPK8,MBD4,MEIS2,MEN1,MGMT,MSH6,MTOR,NABP2,NEDD4,NF1,NIPBL,NLGN3,NMU,NPS,NR2E3,PAPD4,PDC,PDE6C,PDE6G,PIAS1,POLG,POLK,PPID,PPM1D,PPP1CC,PPP1R1B,PRKDC,PTGS2,RAD9B,RBM4B,RHO,RHOB,RS1,SEMA5B,SFRP2,SLC1A3,SLC24A1,SLC4A10,SMC1A,STK11,TAF1,TANC1,TANK,TIPIN,TMEM161A,TNFRSF11A,TP53BP1,TP53I13,TP73,UBE2A,UBE2B,UBE4B,USP1,USP47,XRCC3	MammalFishAncestor	93.4862
GO.Biological.Process	GO:0031129	inductive.cell-cell.signaling	301	2.836685e-98	3.664146e-94	1.217324e-96	6.589584e+0	SALL1	MammalFishAncestor	93.436
GO.Biological.Process	GO:0048534	hematopoietic.or.lymphoid.organ.development	302	4.653461e-98	6.010876e-94	1.990356e-96	1.336565e+0	ABI1,ADAM17,ANXA2,ARIH2,ASXL1,ATM,ATP11C,ATP7A,BATF,BRCA2,C12orf29,CBFA2T3,CCNB2,CD248,CD4,CD40LG,CDH17,CEBPD,CRKL,CSF2,CUL4A,CXCR5,CYLD,DCSTAMP,DLL4,DNAJA3,EFNA2,EIF2AK1,EP300,ERCC2,EVI2B,F2RL1,FARP2,FLT3,FNIP1,FOXP1,FZD8,GAB2,GAS6,GATA3,GFI1,GLI3,HERC6,HOXA3,HOXB3,HOXB4,HOXB7,HYAL2,IL3,INHA,INHBA,JAG1,KCNAB2,KDR,KIT,KITLG,KMT2A,LEF1,LEPR,LMO4,LRRC8A,LRRK1,MAD1L1,MAP2K1,MECOM,MED1,MEF2C,MEIS1,MLF1,MMP21,MT1G,MYO1E,NFE2L1,NFKB2,NKAP,ONECUT1,OSTM1,PAPD4,PAX1,PDGFRA,PGM3,PIK3CD,PITX2,PLCL2,PPARG,PPP2R3C,PPP3CB,PREX1,PRKDC,PRRC2C,PRTN3,PTPN2,PTPN6,PTPRZ1,PYGO1,RAF1,RASGRP4,RBM15,RBM47,RHOH,RORA,RRS1,RUNX3,SART3,SATB1,SBNO2,SFRP2,SH3PXD2A,SHH,SIN3A,SIX1,SIX4,SLC11A2,SOX6,SP3,SPNS2,SPTA1,STAT3,STAT5B,STK11,STK3,TAZ,TBX1,TBX21,TCF7,TCTA,TET2,TGFBR3,TNFRSF11A,TNFSF11,TPO,TSC1,TUSC2,TWSG1,TYRO3,VPS33A,WDR7,WNT2B,ZBTB24,ZFP36L2	MammalFishAncestor	93.2211
GO.Biological.Process	GO:0009119	ribonucleoside.metabolic.process	303	4.868372e-98	6.288476e-94	2.075405e-96	1.571259e+0	ACAT1,ACLY,ADK,ADSS,ADSSL1,AFG1L,AHCYL1,AK4,AK5,AK9,ALDOC,AMD1,AMPD3,APRT,ATP1A2,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP5S,ATP6V0A1,ATP6V0A2,ATP6V1A,COX6C,COX7B,COX8C,CROT,DLD,DLG4,ENO1,ENO2,ENO4,ENSG00000266953,GALK1,GAMT,GAPDH,GNAI3,GPHN,GPI,HK1,HKDC1,HMGCR,IMPDH2,MAGI3,MBIP,MFN1,MYH3,MYH4,MYH8,NADK,NDUFA1,NDUFA12,NDUFA13,NDUFA5,NDUFAF7,NDUFB10,NDUFB5,NDUFS1,NDUFS6,NDUFS7,NDUFV2,NME4,NMNAT1,NT5C2,NT5E,NUDT3,OGDH,OLA1,PAPSS1,PDC,PDCL2,PFKM,PGAM4,PGK1,PGM1,PRPS2,PRTFDC1,RAB23,SLC25A13,SLC35B2,SLC35B3,STOML2,SULT6B1,TAZ,TPI1,UCKL1,UMPS,UPP2,UQCRHL,UQCRQ	MammalFishAncestor	93.2015
GO.Biological.Process	GO:0043570	maintenance.of.DNA.repeat.elements	304	9.511520e-98	1.228603e-93	4.041457e-96	4.930987e+0	TCF7L2	MammalFishAncestor	92.9106
GO.Biological.Process	GO:0002252	immune.effector.process	305	1.283489e-97	1.657883e-93	5.435681e-96	1.331109e+0	ABCC9,ABI1,ACAA1,ACLY,ACTB,ACTG1,ADAM10,ADAM17,AIMP1,ALDOC,AMPD3,ANXA2,ANXA3,APBB1IP,APEH,APRT,ARHGAP45,ARHGAP9,ARPC3,ARSA,ARSB,ATG7,ATP11B,ATP6V0A1,ATP6V1D,ATP7A,AZU1,BAIAP2,BATF,BIN2,BRI3,BTN3A2,C19orf66,C1R,C1RL,C1S,C2,C5AR1,CARD9,CD180,CD40LG,CDH17,CEP290,CFB,CFD,CHGA,CNN2,CNOT7,COPB1,CPNE1,CTSS,CYFIP1,DDOST,DDX3X,DENND1B,DHX58,DIAPH1,DNAJC13,DNAJC3,DNAJC5,DOCK1,DYNC1H1,EIF2AK4,ELANE,ERP44,EXOC1,F2RL1,FOLR3,FOXP1,FYN,GALNS,GATA3,GBF1,GBP1,GBP3,GCA,GCNT3,GHDC,GPI,GPR84,HCK,HERC5,HEXB,HPSE,HSP90AA1,HUWE1,HVCN1,HYAL2,ICAM1,IDH1,IFIH1,IMPDH2,IQGAP2,IRF5,JAG1,JUP,KCNAB2,KCNJ8,KIT,LAMP1,LAMP2,LAMTOR1,LEF1,LPCAT1,LRP1,LSM14A,LTA4H,LYST,MAGT1,MASP2,METTL7A,MSH6,MYH2,NCBP3,NCKIPSD,NEU1,NR4A3,P2RX1,PA2G4,PAK1,PGM1,PIK3CB,PIK3CD,PIK3R2,PKP1,PLAC8,PLCG1,PLCL2,PLPP4,POLR3B,POLR3G,POLR3H,PPIA,PRF1,PRKCD,PRTN3,PSMA5,PSMB7,PSMD11,PSMD12,PSMD14,PSMD2,PSMD6,PTPN6,PTPRN2,PYGL,QSOX1,RAB10,RAB18,RAB27A,RAB3A,RAB5C,RAP1A,RGCC,RHOA,RHOF,ROCK1,RORA,SBNO2,SCAMP1,SERINC5,SERPINA3,SETD2,SLC2A5,SNAP23,SNAP25,SNAP29,SPTAN1,SRP14,STAT1,STAT3,STXBP3,SWAP70,TLR7,TLR8,TMEM30A,TRIM11,TSC1,TUBB4B,TUSC2,TXNDC5,UBR4,UNC13D,VCL,WASL,WIPF1,ZMYND11	MammalFishAncestor	92.7804
GO.Biological.Process	GO:0000768	syncytium.formation.by.plasma.membrane.fusion	306	2.003847e-97	2.588369e-93	8.458723e-96	2.667640e+0	ADAM12,ADGRB3,DCSTAMP,NOS1,PITX2,SBNO2,SH3PXD2A,TANC1,TCTA	MammalFishAncestor	92.587
GO.Biological.Process	GO:0048385	regulation.of.retinoic.acid.receptor.signaling.pathway	307	2.597948e-97	3.355769e-93	1.093085e-95	3.241811e+0	ASXL1,CTBP2,DHRS3,NR2C1,ZNF536	MammalFishAncestor	92.4742
GO.Biological.Process	GO:0048566	embryonic.digestive.tract.development	308	3.006243e-97	3.883164e-93	1.260768e-95	2.015834e+0	ALDH1A2,GLI2,GLI3,HNF1B,ID2,NIPBL,PCSK5,PDGFRA,PITX2,RARB,SALL1,SHH,SHOX2,SIX2,TCF7	MammalFishAncestor	92.4108
GO.Biological.Process	GO:0007159	leukocyte.cell-cell.adhesion	309	3.384207e-97	4.371380e-93	1.414686e-95	1.531010e+0	ADAM17,APBB1IP,ATP7A,BATF,CD4,CD40LG,CYLD,DDOST,DLL4,DNAJA3,DOCK8,DPP4,EIF2AK4,F2RL1,FKBP1B,FOXP1,FYN,FZD8,GATA3,GCNT1,GLI3,ICAM1,KIT,LEF1,LEPR,NEDD4,NKAP,NT5E,PAX1,PIK3CD,PPP3CB,PREX1,PRKDC,PTPN2,RAB27A,RHOH,ROCK1,RORA,SATB1,SELPLG,SHH,SMAD3,SP3,STAT3,STAT5B,STK11,STOML2,TBX21,TCF7,TSC1,WASHC1,ZFP36L2	MammalFishAncestor	92.3594
GO.Biological.Process	GO:0060271	cilium.assembly	310	3.557033e-97	4.594620e-93	1.482135e-95	1.533787e+0	ABCC4,AKAP9,ARMC4,ATP6V1D,BBIP1,BBS10,BBS2,BBS5,C5orf42,CC2D2A,CCDC39,CCDC63,CCNO,CEP131,CEP135,CEP152,CEP164,CEP192,CEP290,CEP76,CFAP46,CFAP74,CLASP1,CSNK1D,DCTN2,DNAAF4,DNAH1,DNAH5,DNAH7,DNAH8,DRC1,DYNC1H1,DYNC1I2,DYNC2H1,DYNC2LI1,DZIP1,ENSG00000248710,ENSG00000251569,FAM161A,FBF1,FLNA,FOPNL,GALNT11,HAUS1,HSP90AA1,ICK,IFT122,IFT43,IFT80,IFT81,IFT88,IQUB,KIF17,KIF3A,KIF3B,KIF3C,MARK4,MKKS,NDE1,NEK1,NEK2,NEURL1,NOTCH1,NPHP3,ODF2,OFD1,ONECUT1,ONECUT2,PARVA,PIBF1,PTPN23,RAB11A,RAB23,RABL2B,RFX4,RILP,RILPL1,RILPL2,RPGRIP1L,SDCCAG8,SEPT2,SNAP29,SPAG1,SPAG17,SSX2IP,TCTN1,TCTN2,TEKT2,TMEM67,TNPO1,TRIM59,TTC21B,TTC30A,TTC30B,TTC8,TTLL5,TUBA4A,TUBB4B,TUBG1,UBE2B,WDPCP,WDR19,WDR34,ZMYND10	MammalFishAncestor	92.3378
GO.Biological.Process	GO:0008610	lipid.biosynthetic.process	311	3.696753e-97	4.775096e-93	1.535401e-95	1.370776e+0	ABCB11,ABHD3,ACACA,ACACB,ACLY,ACP6,ACSF3,ACSL1,ACSL3,ACSM4,ADM,AGPS,ALDH1A2,ALDH1A3,ARV1,ATM,B3GALT1,CBR4,CERS2,CERS4,CERS6,CES1,CFTR,CHPT1,CLN8,COL4A3BP,COQ2,CPNE1,CRH,CYP17A1,CYP19A1,CYP2R1,CYP51A1,CYP7B1,DECR2,DHCR24,DHRS9,DOLK,ELOVL3,ELOVL5,ERG28,FASN,FDX2,FGF16,FGF20,FGF5,FGF8,FIG4,GGPS1,GNPAT,GPAT3,HACD2,HACD3,HEXB,HMGCR,HSD17B1,IDI1,IDI2,INPP5E,INPP5F,INPPL1,INSIG1,IRS2,ISYNA1,KL,KLB,LIAS,LIPC,LPCAT1,LPCAT2,LPCAT3,LPGAT1,LPIN2,LTA4H,MBOAT2,MOGAT1,MSMO1,MTMR14,MTMR7,MVK,MYO5A,OSBPL1A,OSBPL6,OSBPL7,OXSM,P2RX1,PCYT1B,PDSS1,PI4KA,PIGB,PIGC,PIGK,PIGL,PIGN,PIGO,PIGQ,PIGS,PIGV,PIGY,PIK3CB,PIK3CD,PIK3R2,PIK3R3,PIK3R4,PIK3R5,PIK3R6,PIKFYVE,PIP4K2C,PITPNM2,PLA2G4A,PLA2G4B,PLA2G4F,PLCE1,PLPP1,PNPLA8,PRKAB1,PRKD2,PRKD3,PTGES3,PTGS2,PTPN13,PYURF,RAB4A,SAMD8,SBF1,SCD5,SERINC5,SGMS2,SGPP2,SLC44A4,SPHK1,SRD5A3,SREBF1,ST6GALNAC5,ST8SIA3,ST8SIA5,STARD3,STARD7,TAMM41,TAZ,TFCP2L1	MammalFishAncestor	92.321
GO.Biological.Process	GO:0034622	cellular.macromolecular.complex.assembly	312	4.372994e-97	5.648596e-93	1.810448e-95	1.327471e+0	AARS2,AGO1,AGO3,AGO4,AKAP9,ARMC4,ATF1,ATP6V0A1,ATP6V0A2,ATPAF2,ATRX,AXIN1,BBS10,BCS1L,BRD2,CADPS,CAND2,CASQ1,CCDC39,CCDC63,CCNH,CDT1,CENPI,CENPU,CENPV,CHAF1B,CIRBP,CLASP1,CLTC,CNOT7,COBLL1,CORO7,CSNK1D,CTTN,CUL4A,CUL4B,DACH1,DDX1,DDX20,DDX23,DDX3X,DDX6,DENR,DHX9,DIAPH1,DICER1,DMAC1,DMXL1,DMXL2,DNAAF4,DNAH1,DNAH5,DNAH7,DNAH8,DNM3,DRC1,DYNC1H1,EIF4B,ERCC2,EXOC8,FAM103A1,FCHO2,FGA,FGB,FGG,FKBP4,GPX4,GTF2A2,GTF2B,GTF3C5,H1FOO,H3F3B,HAT1,HDGFL3,HIP1R,HIST1H1A,HIST1H1C,HIST1H1D,HIST1H1E,HIST1H1T,HIST1H2BB,HIST1H2BC,HIST1H2BD,HIST1H2BE,HIST1H2BF,HIST1H2BG,HIST1H2BH,HIST1H2BI,HIST1H3A,HIST1H3B,HIST1H3C,HIST1H3D,HIST1H3E,HIST1H3F,HIST1H3G,HIST1H4A,HIST1H4B,HIST1H4C,HIST1H4D,HIST1H4E,HIST1H4F,HIST1H4G,HIST1H4H,HLA-DMA,HLA-DMB,HNF1B,HP1BP3,HSP90AA1,HSPA4,IMMP1L,IMMP2L,ITGB3BP,KAT6B,LMOD2,LSM14A,LSM4,LUC7L,LUC7L3,MAP7D3,MCMDC2,MCTS1,MDN1,MICALL2,MKKS,MNAT1,MPV17L2,MSRB1,MYBPC1,MYBPC2,MYBPC3,MYBPHL,MYH11,MYOM1,MYOM2,MZT1,NAP1L1,NAP1L5,NDE1,NDEL1,NDUFA1,NDUFA12,NDUFA13,NDUFA5,NDUFAF3,NDUFAF7,NDUFAF8,NDUFB10,NDUFB5,NDUFS1,NDUFS6,NDUFS7,NDUFV2,NIN,NOP2,NUP93,OBSL1,OGFOD1,PCDHGA3,PIAS1,PPAN,PPAN-P2RY11,PREX1,PRPF3,PRPF6,PSIP1,PSMD11,PSMG2,PTGES3,PUM2,RBM5,RBMX,RBX1,RIC3,RPA1,RPF1,RPF2,RPL10,RPL3L,RPL5,RPS10,RPS15,RPS27L,RRS1,RSL24D1,RTN4,SAR1A,SART3,SDHAF4,SEC24A,SEC24C,SEC24D,SEC31A,SET,SETSIP,SF1,SF3A3,SFSWAP,SHPRH,SHQ1,SKP1,SLAIN2,SMAD1,SMAD3,SNAP23,SNAP25,SNAP29,SNRNP200,SNRPC,SNRPD1,SNRPF,SNUPN,SPAG1,SRP54,SRPK3,TAF1,TAF11,TAF1B,TAF2,TAF4,TAF7,TAF7L,TAZ,TBCA,TCAP,TEKT2,TGFBR3,TM9SF4,TMEM33,TOMM20,TRPV4,TSPYL2,TTC19,TUBG1,TUBG2,TUBGCP4,TUBGCP5,TUBGCP6,TXNL4B,UBA52,UBB,UBE2K,UNC13B,UQCC2,USH1C,USP4,VAMP4,VIL1,WASF1,WASF3,XRCC3,ZFYVE9,ZMYND10,ZNF207	MammalFishAncestor	92.2481
GO.Biological.Process	GO:1901657	glycosyl.compound.metabolic.process	313	9.751774e-97	1.259637e-92	4.024398e-95	1.523607e+0	ACAT1,ACLY,ADK,ADSS,ADSSL1,AFG1L,AHCYL1,AK4,AK5,AK9,ALDOC,AMD1,AMPD3,APRT,ATIC,ATP1A2,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP5S,ATP6V0A1,ATP6V0A2,ATP6V1A,CBR4,COX6C,COX7B,COX8C,CROT,DLD,DLG4,DPYS,ENO1,ENO2,ENO4,ENSG00000266953,GALK1,GAMT,GAPDH,GNAI3,GPHN,GPI,HK1,HKDC1,HMGCR,IMPDH2,KL,KLB,LCTL,MAGI3,MBIP,MFN1,MYH3,MYH4,MYH8,NADK,NDUFA1,NDUFA12,NDUFA13,NDUFA5,NDUFAF7,NDUFB10,NDUFB5,NDUFS1,NDUFS6,NDUFS7,NDUFV2,NME4,NMNAT1,NT5C2,NT5E,NUDT3,OGDH,OLA1,PAPSS1,PDC,PDCL2,PFKM,PGAM4,PGK1,PGM1,PPAT,PRPS2,PRTFDC1,RAB23,SLC25A13,SLC35B2,SLC35B3,STOML2,SULT6B1,TAZ,TPI1,UCKL1,UMPS,UPP2,UQCRHL,UQCRQ	MammalFishAncestor	91.8998
GO.Biological.Process	GO:0019049	evasion.or.tolerance.of.host.defenses.by.virus	314	1.307105e-96	1.688388e-92	5.377030e-95	9.085608e+0	SMAD3	MammalFishAncestor	91.7725
GO.Biological.Process	GO:0006949	syncytium.formation	315	1.450657e-96	1.873814e-92	5.948615e-95	2.653920e+0	ADAM12,ADGRB3,DCSTAMP,NOS1,PITX2,SBNO2,SH3PXD2A,TANC1,TCTA	MammalFishAncestor	91.7273
GO.Biological.Process	GO:0050882	voluntary.musculoskeletal.movement	316	1.772772e-96	2.289890e-92	7.246486e-95	6.404108e+0	ITPR1,MTOR,VTI1A	MammalFishAncestor	91.6402
GO.Biological.Process	GO:0061082	myeloid.leukocyte.cytokine.production	317	2.423267e-96	3.130134e-92	9.874240e-95	5.681092e+0	CHGA,GAS6,KIT	MammalFishAncestor	91.5044
GO.Biological.Process	GO:0046034	ATP.metabolic.process	318	4.664499e-96	6.025133e-92	1.894696e-94	1.858724e+0	AFG1L,AK4,AK5,AK9,ALDOC,AMPD3,ATP1A2,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP5S,ATP6V0A1,ATP6V0A2,ATP6V1A,COX6C,COX7B,COX8C,DLD,ENO1,ENO2,ENO4,ENSG00000266953,GALK1,GAPDH,GPI,HK1,HKDC1,MYH3,MYH4,MYH8,NADK,NDUFA1,NDUFA12,NDUFA13,NDUFA5,NDUFAF7,NDUFB10,NDUFB5,NDUFS1,NDUFS6,NDUFS7,NDUFV2,NMNAT1,OGDH,OLA1,PFKM,PGAM4,PGK1,PGM1,SLC25A13,STOML2,TAZ,TPI1,UQCRHL,UQCRQ	MammalFishAncestor	91.22
GO.Biological.Process	GO:0008589	regulation.of.smoothened.signaling.pathway	319	1.218320e-95	1.573704e-91	4.933241e-94	1.899115e+0	BTRC,CHSY1,DLG5,DYNC2H1,GLI1,GLI2,GLI3,GLIS2,HHIP,IFT122,KCTD11,OTX2,PRKACB,PTCH1,RFX4,RORA,RPGRIP1L,SALL3,SCUBE3,SHH,SHOX2,TCTN1,TTC21B,ZIC1	MammalFishAncestor	90.8031
GO.Biological.Process	GO:0006304	DNA.modification	320	1.478958e-95	1.910370e-91	5.969906e-94	2.202615e+0	ALKBH2,ALKBH5,ASCC3,ASZ1,ATRX,BAZ2A,DNMT1,DNMT3A,EHMT1,EHMT2,FOS,FTO,GATAD2A,KMT2A,MBD4,MGMT,NTHL1,PPM1D,SMUG1,TDRD1,TET1,TET2,UNG	MammalFishAncestor	90.7189
GO.Biological.Process	GO:0007346	regulation.of.mitotic.cell.cycle	321	1.578142e-95	2.038486e-91	6.350424e-94	1.340647e+0	AATF,ADAM17,AFAP1L2,AKAP9,AKT1,ANAPC10,ANAPC15,ANAPC7,ARID3A,ATF2,ATM,ATRX,BORA,BRCA2,BRD7,BTRC,BUB1B,BUB3,CCSAP,CDC7,CDK11A,CDK11B,CDK19,CDK3,CDK5RAP3,CDK8,CDT1,CEP131,CEP135,CEP152,CEP164,CEP192,CEP290,CEP76,CHFR,CLASP1,CLSPN,CLTC,CNOT7,CNOT9,CSNK1D,CTDSPL,CUL4A,CUL4B,CUL9,CYLD,DCTN2,DDX3X,DMRT1,DRD3,DTL,DYNC1H1,DYNC1I2,EIF4G1,EP300,ERCC2,FANCI,FAP,FBXO43,FGF8,FHL1,FOXN3,GBF1,GPSM2,HAUS1,HSP90AA1,HYAL1,ID2,INO80,KANK2,KIF14,KNTC1,LSM10,MAD1L1,MAP2K1,MAP2K5,MAP4K2,MAP4K5,MEIS2,MIIP,MKI67,NABP2,NACC2,NDE1,NEK1,NEK2,NEK6,NEK7,NUMA1,OBSL1,ODF2,OFD1,OXSR1,PAK1,PAK5,PAK6,PHB2,PHOX2B,PIM3,PKD1,PKD2,PKN2,PLRG1,PPP1R9B,PRKCA,PRKDC,PSMA1,PSMA5,PSMA6,PSMA7,PSMB2,PSMB7,PSMB8,PSMB9,PSMD11,PSMD12,PSMD14,PSMD2,PSMD6,PSMG2,PSRC1,PTCH1,PTPN6,RAB11A,RAD9B,RANBP1,RANBP2,RBL2,RBX1,RGCC,RPS27L,RPS6KB1,SDCCAG8,SFN,SIN3A,SKP1,SLF1,SLF2,SLK,SMAD3,SMARCA4,SMARCD3,SMC1A,SMC3,SPHK1,STAG1,STAT5B,STK24,STK25,STK3,STK39,STOX1,SYF2,TAOK1,TAOK3,TFAP4,TFDP1,TIPIN,TNIK,TOM1L2,TOP2B,TP73,TPR,TTC28,TUBA4A,TUBB4B,TUBG1,UBA52,UBB,USP44,USP47,XRCC3,ZFP36L2,ZNF207,ZWILCH	MammalFishAncestor	90.6907
GO.Biological.Process	GO:0050881	musculoskeletal.movement	322	2.064177e-95	2.666297e-91	8.280427e-94	3.263019e+0	CHRNA1,CHRNB1,DRD3,HOMER1,ITPR1,MTOR,MYH3,MYH8,RPS6KB1,STAC3,TCAP,TNNC1,TNNI1,VPS54,VTI1A	MammalFishAncestor	90.5741
GO.Biological.Process	GO:0072081	specification.of.nephron.tubule.identity	323	2.468182e-95	3.188151e-91	9.870436e-94	3.409142e+0	IRX1,IRX2,IRX3	MammalFishAncestor	90.4965
GO.Biological.Process	GO:1902580	single-organism.cellular.localization	324	4.078817e-95	5.268608e-91	1.626114e-93	1.282745e+0	ABCA1,ACACA,ACACB,AGRN,AKAP9,AKT1,ANK2,ANK3,ANXA2,AP3B1,AP3B2,AP3M1,ARFRP1,ARHGAP21,ARL5A,ATG4B,ATG4C,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5G1,ATP5G3,ATP5L,ATP5S,BBIP1,BBS2,BBS5,BLOC1S5,BMF,CACNB3,CADPS,CAPN3,CEP131,CES1,CHGA,CLASP1,CLIP1,COL4A3BP,CPE,CPT1B,CSE1L,DAG1,DCTN2,DLG4,DNAJA3,DNAJC5,DNAJC6,DNLZ,DNM3,DST,DYNC1H1,DYNC1I1,DYNC1I2,DYNC2H1,DYNC2LI1,ENSG00000258472,EYA1,FAM53B,FCHO2,FLNA,GAS6,GLRB,GOLPH3L,GPHN,GPN3,GPR158,GPSM2,GRIN3B,GRPEL1,HEATR3,HPS6,HSP90AA1,HSPA4,HTT,ICK,ICMT,IFT122,IFT43,IFT80,IFT81,IFT88,IPO9,ITGB1BP1,JUP,KIF17,KIF1A,KIF1B,KIF23,KIF3A,KIF3B,KIF3C,KIF5A,KIF5B,KIT,KLC3,KPNA2,KPNA4,KRT18,LDLR,LDLRAP1,LIN7A,LRPPRC,MACF1,MKKS,MOAP1,MPP5,MT3,MYO5A,MYO7A,NCKIPSD,NDE1,NDEL1,NDUFA13,NFKBIA,NLGN2,NLGN3,NR4A3,NRXN1,NUMA1,NUP133,NUP188,NUP210,NUP214,NUP93,OTOF,PACS1,PACSIN1,PALM,PAM16,PARD3,PAX6,PCLO,PEX14,PEX2,PEX5,PEX5L,PHB2,PIK3CD,POLR2M,PRKCZ,PRKG2,PTCH1,RAB10,RAB11A,RAB27A,RAB32,RAB3A,RABL2B,RAN,RANBP1,RANBP2,RAPGEF2,RAPGEF6,RELN,RERE,RHOT1,RHOT2,RILPL1,RILPL2,RIMS2,ROCK1,RPL10,RPL19,RPL21,RPL22,RPL27A,RPL30,RPL32,RPL35,RPL39,RPL4,RPL41,RPL5,RPL9,RPLP1,RPS10,RPS15,RPS2,RPS26,RPS3A,SAR1A,SEC24A,SEC24C,SEC24D,SEC31A,SEC63,SEH1L,SH3GL2,SIX2,SIX3,SKAP1,SLC25A20,SLMAP,SNAP23,SNAP25,SNAP29,SNUPN,SPAG5,SPIRE1,SPTBN1,SPTBN4,SRP14,SRP54,SRP68,SRP72,SSB,SSX2IP,STAT3,STOML2,STX2,SYNE3,SYP,SYT1,SYT2,SYT3,TAP1,TMEM88,TNIK,TNPO1,TNPO3,TOB1,TOMM20,TPR,TRAM1,TRIM9,TSC1,TSC2,TSPAN15,TTC21A,TTC21B,TTC30A,TTC30B,TUB,UBA52,UBB,UNC13B,UNC13C,WASHC1,WASL,WDR19,WDR34,WNK3,WNT7A,ZDHHC23,ZFYVE9	MammalFishAncestor	90.2783
GO.Biological.Process	GO:0071559	response.to.transforming.growth.factor.beta	325	9.822514e-95	1.268774e-90	3.903920e-93	1.588989e+0	ACVR1,BAMBI,COL1A1,COL1A2,COL4A2,DLX1,FBN1,FOS,FYN,GDF15,GDF9,HYAL2,LIMS1,LTBP2,MEF2C,MEN1,NODAL,PARD3,PDCD5,POSTN,PPM1A,PRKCZ,RHOA,RUNX3,SMAD1,SMAD3,SMAD6,SMAD9,SOX6,TGFB3,TGFBR3,TWSG1,UBA52,UBB,USP9X,USP9Y,WFIKKN2,WNT2,WNT7A,ZFHX3,ZFP36L2,ZFYVE9	MammalFishAncestor	89.8966
GO.Biological.Process	GO:0001944	vasculature.development	326	1.183139e-94	1.528261e-90	4.687916e-93	1.313573e+0	ACVR1,ADAMTS9,ADIPOR2,ADM,AIMP1,AKT1,ALDH1A2,ANGPTL3,ANGPTL6,ANXA2,APOB,ARHGAP22,ARHGAP24,ARID1A,ATP5B,ATP7A,BCAS3,C5orf42,CDX2,CLIC4,COL1A1,COL1A2,COL4A1,COL4A2,CRKL,CSPG4,DAG1,DDIT3,DLL4,DYNC2H1,ECM1,EDNRA,ELK3,ENPEP,EYA1,FAP,FGF8,FLT1,FN1,FOLR1,FZD8,GATA6,GJA5,GLI3,GLMN,GPI,GPX1,HOXA1,HOXA3,HOXA7,HOXB13,HOXB3,HPSE,HSPG2,HTATIP2,IMMP2L,ITGB1BP1,JAG1,KDR,KLF5,LEF1,LEPR,LRP1,LRP2,LTBP1,MAP2K1,MED1,MEF2C,MEGF8,MEIS1,MIB1,MMP2,MMP21,MYO1E,NEDD4,NF1,NODAL,NOTCH1,NOV,NOX1,NR2F2,NRARP,NRCAM,NRP2,OTULIN,PARVA,PAX6,PCSK5,PDE3B,PDGFRA,PGF,PIK3CB,PIK3R6,PITX2,PKD1,PKD2,PLCD1,PLXND1,POFUT1,PPP3CB,PRKCA,PRKD2,PROK1,PROK2,PROX1,PROX2,PTGS2,PTPN14,RAPGEF2,RASA1,RBM15,RHOB,RNF213,RORA,SERPINF2,SETD2,SFRP2,SHH,SIX1,SMAD6,SOX18,SPHK1,STK11,TBX1,TBX2,TBX4,TCF7L2,TGFBR3,TNFSF12,VASH1,WNT2,WNT7A,WT1,ZFPM2,ZNF304	MammalFishAncestor	89.8158
GO.Biological.Process	GO:0006413	translational.initiation	327	1.495044e-94	1.931148e-90	5.905652e-93	2.042326e+0	ABCE1,COPS5,DDX3Y,DENR,DHX29,EIF2B2,EIF2S1,EIF3G,EIF3M,EIF4B,EIF4E3,EIF4G1,EIF4G2,EIF4G3,MCTS1,MTIF3,PABPC1,PTBP1,RPL10,RPL19,RPL21,RPL22,RPL27A,RPL30,RPL32,RPL35,RPL39,RPL4,RPL41,RPL5,RPL9,RPLP1,RPS10,RPS15,RPS2,RPS26,RPS3A,SSB,UBA52,YAE1D1	MammalFishAncestor	89.7142
GO.Biological.Process	GO:0007015	actin.filament.organization	328	2.289533e-94	2.957390e-90	9.016432e-93	1.619673e+0	ABI1,ACTA1,ACTC1,ARHGAP12,ARPC3,ARPC5L,BAIAP2,BAIAP2L1,CGNL1,COBLL1,CORO7,CTTN,DIAPH1,ERMN,FLNA,FRY,FRYL,FSCN1,FSCN2,INPPL1,IQGAP2,JMY,LMOD2,MICAL2,MICALL2,MSRB1,MYBPC1,MYBPC2,MYBPC3,MYBPHL,MYOM1,MYOM2,OBSL1,PACSIN1,PPP1R9A,PREX1,PROX1,RHOA,RHOF,RND1,SHROOM1,SHTN1,SPIRE1,SPTA1,SWAP70,TCAP,TMSB4X,TNNT2,TPM1,TRPV4,USH1C,VIL1,WASF1,WASF3,WASHC1,WASL,WHAMM,WIPF1	MammalFishAncestor	89.5291
GO.Biological.Process	GO:0010389	regulation.of.G2/M.transition.of.mitotic.cell.cycle	329	2.904303e-94	3.751488e-90	1.140270e-92	1.742600e+0	AKAP9,ATM,CDC7,CDK3,CDK5RAP3,CEP131,CEP135,CEP152,CEP164,CEP192,CEP290,CEP76,CLASP1,CLSPN,CSNK1D,DCTN2,DTL,DYNC1H1,DYNC1I2,FANCI,FHL1,FOXN3,HAUS1,HSP90AA1,KIF14,MIIP,NDE1,NEK2,ODF2,OFD1,PHOX2B,PSMA1,PSMA5,PSMA6,PSMA7,PSMB2,PSMB7,PSMB8,PSMB9,PSMD11,PSMD12,PSMD14,PSMD2,PSMD6,RAB11A,RBX1,SDCCAG8,SIN3A,SKP1,SMARCD3,STOX1,SYF2,TAOK3,TUBA4A,TUBB4B,TUBG1,UBA52,UBB,USP47	MammalFishAncestor	89.4258
GO.Biological.Process	GO:0007183	SMAD.protein.complex.assembly	330	5.648322e-94	7.295938e-90	2.210890e-92	4.672855e+0	SMAD1,SMAD3,ZFYVE9	MammalFishAncestor	89.1369
GO.Biological.Process	GO:2001214	positive.regulation.of.vasculogenesis	331	5.808590e-94	7.502956e-90	2.266754e-92	3.902118e+0	ADM,ASB4,HIF1AN,KDR,RAP1A,RAPGEF2	MammalFishAncestor	89.1248
GO.Biological.Process	GO:0019319	hexose.biosynthetic.process	332	5.825162e-94	7.524362e-90	2.266374e-92	2.624599e+0	ALDOC,CHST15,CRTC2,ENO1,ENO2,ENSG00000266953,G6PC2,GAPDH,GPD2,GPI,MDH1,PGAM4,PGK1,PGM1,RBP4,SLC25A12,SLC25A13,TPI1	MammalFishAncestor	89.1235
GO.Biological.Process	GO:1901509	regulation.of.endothelial.tube.morphogenesis	333	6.633587e-94	8.568604e-90	2.573154e-92	5.213898e+0	FOXP1	MammalFishAncestor	89.0671
GO.Biological.Process	GO:0016125	sterol.metabolic.process	334	7.354277e-94	9.499520e-90	2.844168e-92	1.898145e+0	ABCA1,ACLY,ANGPTL3,APOB,ARV1,CEL,CES1,CFTR,CLN8,CUBN,CYP17A1,CYP19A1,CYP51A1,CYP7B1,DHCR24,ERG28,FDX2,GGPS1,HDLBP,HMGCR,IDI1,IDI2,INSIG1,LDLR,LDLRAP1,LEPR,LIPC,MSMO1,MT3,MVK,OSBPL1A,PCSK9,PON1,SCAP,SCARF1,SREBF1,STARD3,VLDLR	MammalFishAncestor	89.0223
GO.Biological.Process	GO:0048732	gland.development	335	8.010304e-94	1.034691e-89	3.088630e-92	1.341518e+0	ABCB4,ACAT1,ACO2,AK4,AKT1,ALDH1A2,ALDH1A3,APRT,ASXL1,ATM,ATP7A,BTRC,CCDC39,CCNB2,CELA1,CLCN2,CRH,CRKL,CYP19A1,CYP7B1,DAG1,DKK3,EDAR,ESR1,FASN,FGF8,FKBP4,FOXB1,GATA3,GATA6,GDF7,GFER,GLI1,GLI2,GLI3,GSX1,HFE,HNF1B,HNRNPD,HOXA3,HOXA5,HOXB13,HOXB3,HOXB9,HOXD13,HOXD3,HOXD9,ID2,INSM1,IRS2,KALRN,KDM5B,KRT76,LEF1,LHX3,LMO4,MAD1L1,MAP2K1,MDK,MED1,MGMT,NEURL1,NF1,NFKBIA,NKX2-1,NKX2-8,NODAL,NOTCH1,NPHP3,NR5A1,NTN1,ONECUT1,ONECUT2,OTP,PAX1,PAX6,PCSK9,PDGFRA,PDX1,PHB2,PITX1,PITX2,PKD1,PKD2,PLXND1,POU3F2,PPAT,PPDPF,PRKDC,PROX1,PTCH1,RAF1,RAP1A,RB1CC1,RPGRIP1L,RPL32,SALL1,SEC63,SHH,SIX1,SIX3,SIX4,SLC6A3,SMAD3,SMARCC1,SOX2,SP3,STAT5A,STAT5B,SULF2,TBX1,TBX2,TFCP2L1,TGFB3,TGFBR3,TNFRSF11A,TNFSF11,TWSG1,UMPS,WNT2,WT1	MammalFishAncestor	88.9852
GO.Biological.Process	GO:0044334	canonical.Wnt.signaling.pathway.involved.in.positive.regulation.of.epithelial.to.mesenchymal.transition	336	8.460751e-94	1.092875e-89	3.252605e-92	4.729983e+0	TCF7L2	MammalFishAncestor	88.9614
GO.Biological.Process	GO:0071359	cellular.response.to.dsRNA	337	1.723300e-93	2.225987e-89	6.605302e-92	2.654372e+0	AGO1,AGO3,AGO4,DGCR8,DHX9,DICER1,IFIH1,PDE12,PRKRA,PUM1,PUM2,SMAD1,SMAD3,ZC3H7B	MammalFishAncestor	88.6525
GO.Biological.Process	GO:0001568	blood.vessel.development	338	6.178438e-93	7.980688e-89	2.361150e-91	1.315658e+0	ACVR1,ADAMTS9,ADIPOR2,ADM,AIMP1,AKT1,ALDH1A2,ANGPTL3,ANGPTL6,ANXA2,APOB,ARHGAP22,ARHGAP24,ARID1A,ATP5B,ATP7A,BCAS3,C5orf42,CDX2,CLIC4,COL1A1,COL1A2,COL4A1,COL4A2,CRKL,CSPG4,DAG1,DDIT3,DLL4,DYNC2H1,ECM1,EDNRA,ELK3,ENPEP,EYA1,FAP,FGF8,FLT1,FN1,FOLR1,FZD8,GATA6,GJA5,GLI3,GLMN,GPI,GPX1,HOXA1,HOXA3,HOXA7,HOXB13,HOXB3,HPSE,HSPG2,HTATIP2,ITGB1BP1,JAG1,KDR,KLF5,LEF1,LEPR,LRP1,LRP2,LTBP1,MAP2K1,MED1,MEF2C,MEGF8,MEIS1,MIB1,MMP2,MMP21,MYO1E,NEDD4,NF1,NOTCH1,NOV,NOX1,NR2F2,NRARP,NRCAM,NRP2,OTULIN,PARVA,PAX6,PCSK5,PDE3B,PDGFRA,PGF,PIK3CB,PIK3R6,PITX2,PKD1,PKD2,PLCD1,PLXND1,POFUT1,PRKCA,PRKD2,PROK1,PROK2,PROX1,PTGS2,RAPGEF2,RASA1,RBM15,RHOB,RNF213,RORA,SERPINF2,SETD2,SFRP2,SHH,SIX1,SMAD6,SOX18,SPHK1,TBX1,TBX2,TBX4,TCF7L2,TGFBR3,TNFSF12,VASH1,WNT2,WNT7A,WT1,ZFPM2,ZNF304	MammalFishAncestor	88.098
GO.Biological.Process	GO:0007601	visual.perception	339	6.395499e-93	8.261066e-89	2.436893e-91	1.577105e+0	ABCA4,ABCC6,ADGRV1,ATXN7,BBS10,BBS2,BBS5,CACNA1F,CACNA2D4,CDH23,COL11A1,COL1A1,COL2A1,CRYBA1,CRYGA,CRYGB,CRYGC,CRYGD,DHRS3,DLL4,DNAJC19,FAM161A,FSCN2,GJA10,GJA3,GJA8,GJD2,GLRA1,GLRB,GNAT1,GNAT2,GRK1,HMCN1,IMPG1,IRX5,LAMB2,MIP,MKKS,MYO3A,MYO3B,MYO5A,MYO7A,MYO9A,NR2E1,NR2E3,NYX,OAT,OCLM,PAX2,PAX6,PDC,PDE6C,PDE6G,POU4F3,POU6F2,RBP4,RDH12,RHO,RS1,SEMA5B,SIX3,SIX6,SLC24A1,USH2A,ZIC2	MammalFishAncestor	88.083
GO.Biological.Process	GO:0017183	peptidyl-diphthamide.biosynthetic.process.from.peptidyl-histidine	340	7.102896e-93	9.174811e-89	2.698474e-91	4.751024e+0	DNAJC24,DPH1,DPH6,DPH7	MammalFishAncestor	88.0374
GO.Biological.Process	GO:1904685	positive.regulation.of.metalloendopeptidase.activity	341	1.466720e-92	1.894562e-88	5.555901e-91	1.096612e+1	MBP,STAT3	MammalFishAncestor	87.7225
GO.Biological.Process	GO:0021846	cell.proliferation.in.forebrain	342	2.201633e-92	2.843849e-88	8.315349e-91	2.283696e+0	ARX,CEP120,DCT,DOCK7,EMX2,FGF8,GLI3,KIF14,KIF1A,POU3F2,POU3F3,SIX3,WNT7A,ZEB2	MammalFishAncestor	87.5461
GO.Biological.Process	GO:0045995	regulation.of.embryonic.development	343	2.267630e-92	2.929098e-88	8.539643e-91	1.628792e+0	CCSAP,CDX2,CLASP1,DAG1,DMRT2,DVL2,FOXA2,GATA3,GCM1,HNF1B,LAMA2,LAMA3,LAMA4,LHX1,MAP2K5,MBP,NFE2L2,NIPBL,NKD1,NODAL,NOTCH1,NPHP3,NRARP,OTX2,PHLDB1,PRKACB,RNF207,SFRP2,SHH,SIX1,SIX4,STK3,STOX1,SULF1,TBX2,TENM4,WDPCP,WNT2,WNT2B	MammalFishAncestor	87.5333
GO.Biological.Process	GO:0044782	cilium.organization	344	3.315284e-92	4.282352e-88	1.244870e-90	1.510173e+0	ABCC4,AKAP9,ARMC4,ATP6V1D,BBIP1,BBS10,BBS2,BBS5,C5orf42,CC2D2A,CCDC39,CCDC63,CCNO,CEP131,CEP135,CEP152,CEP164,CEP192,CEP290,CEP76,CFAP46,CFAP74,CLASP1,CSNK1D,DCTN2,DNAAF4,DNAH1,DNAH5,DNAH7,DNAH8,DRC1,DYNC1H1,DYNC1I2,DYNC2H1,DYNC2LI1,DZIP1,ENSG00000248710,ENSG00000251569,FAM161A,FBF1,FLNA,FOPNL,GALNT11,HAUS1,HSP90AA1,ICK,IFT122,IFT43,IFT80,IFT81,IFT88,IQUB,KIF17,KIF3A,KIF3B,KIF3C,MARK4,MKKS,MNS1,NDE1,NEK1,NEK2,NEURL1,NOTCH1,NPHP3,ODF2,OFD1,ONECUT1,ONECUT2,PARVA,PIBF1,PTPN23,RAB11A,RAB23,RABL2B,RFX4,RILP,RILPL1,RILPL2,RPGRIP1L,SDCCAG8,SEPT2,SNAP29,SPAG1,SPAG17,SSX2IP,TCTN1,TCTN2,TEKT2,TMEM67,TNPO1,TRIM59,TTC21A,TTC21B,TTC30A,TTC30B,TTC8,TTLL5,TUBA4A,TUBB4B,TUBG1,UBE2B,WDPCP,WDR19,WDR34,ZMYND10	MammalFishAncestor	87.3683
GO.Biological.Process	GO:0021691	cerebellar.Purkinje.cell.layer.maturation	345	4.516426e-92	5.833867e-88	1.690976e-90	1.050320e+1	RERE	MammalFishAncestor	87.234
GO.Biological.Process	GO:0048708	astrocyte.differentiation	346	8.145389e-92	1.052140e-87	3.040867e-90	2.200579e+0	GCM1,LAMB2,LRP1,MAP2K1,MT3,NF1,NKX2-2,NOTCH1,PAX6,POU3F2,ROR1,SHH,SOX6,STAT3	MammalFishAncestor	86.9779
GO.Biological.Process	GO:0071879	positive.regulation.of.adrenergic.receptor.signaling.pathway	347	9.495505e-92	1.226534e-87	3.534681e-90	4.596122e+0	ARRDC3,NOS1	MammalFishAncestor	86.9113
GO.Biological.Process	GO:0035510	DNA.dealkylation	348	9.644127e-92	1.245732e-87	3.579689e-90	3.193314e+0	ALKBH2,ALKBH5,ASCC3,FTO,MGMT,TET1,TET2	MammalFishAncestor	86.9046
GO.Biological.Process	GO:0048386	positive.regulation.of.retinoic.acid.receptor.signaling.pathway	349	9.950852e-92	1.285352e-87	3.682956e-90	6.570723e+0	ASXL1,CTBP2,NR2C1	MammalFishAncestor	86.891
GO.Biological.Process	GO:0016055	Wnt.signaling.pathway	350	1.691345e-91	2.184710e-87	6.242030e-90	1.410391e+0	AGO1,AGO3,AGO4,APCDD1,AXIN1,BCL9,BCL9L,BRD7,BTRC,CCNE1,CCNY,CELA1,CELSR2,CLTC,CPE,CSNK1A1L,CSNK1D,CTHRC1,CTNNBIP1,CTR9,CYLD,DACT3,DDIT3,DDX3X,DKK2,DKK3,DVL2,FAM53B,FBXW4,FGF8,FZD10,FZD6,FZD8,GATA3,GLI1,GNAO1,GNAT2,GNB1,GSK3B,HOXB9,INVS,KLHL12,LDB1,LEF1,LZTS2,MACF1,MED12,MYOC,NFATC1,NKD1,NPHP3,NR4A2,OTULIN,PDE6G,PITX2,PLCB2,PPM1A,PPP3CB,PRICKLE2,PSMA1,PSMA5,PSMA6,PSMA7,PSMB2,PSMB7,PSMB8,PSMB9,PSMD11,PSMD12,PSMD14,PSMD2,PSMD6,PYGO1,RBX1,RHOA,ROR1,RYR2,SDC1,SFRP2,SHH,SKP1,SMAD3,SNX3,STK11,STRN,TCF7,TCF7L2,TLE3,TMEM198,TMEM88,TNIK,TNRC6A,UBA52,UBB,UBE2B,VPS26A,VPS29,WNT2,WNT2B,WNT5B,WNT7A,ZBTB33,ZRANB1	MammalFishAncestor	86.6606
GO.Biological.Process	GO:0046174	polyol.catabolic.process	351	1.798014e-91	2.322495e-87	6.616794e-90	3.347277e+0	GK2,GK3P,GPD2,INPP5A,INPP5E,MTMR7,NUDT3,TPI1	MammalFishAncestor	86.634
GO.Biological.Process	GO:0010608	posttranscriptional.regulation.of.gene.expression	352	3.214980e-91	4.152790e-87	1.179770e-89	1.405646e+0	AGO1,AGO3,AGO4,AKT1,BARHL2,C12orf65,CDC37,CIRBP,CNOT7,CNOT9,CPEB2,CPEB3,CSDC2,CYFIP1,DCP1A,DDX1,DDX3X,DDX6,DGCR8,DHX36,DHX9,DICER1,DIS3,DNAJC3,EIF2AK1,EIF2AK4,EIF2B2,EIF2S1,EIF4B,EIF4E3,EIF4EBP2,EIF4EBP3,EIF4G1,EIF4G2,EIF4G3,EIF5A,EIF5A2,ENC1,ENSG00000203546,ESR1,EXOSC8,FOXO3,FXR1,GAPDH,GCN1,GLE1,H3F3B,HIST1H3A,HIST1H3B,HIST1H3C,HIST1H3D,HIST1H3E,HIST1H3F,HIST1H3G,HIST1H4A,HIST1H4B,HIST1H4C,HIST1H4D,HIST1H4E,HIST1H4F,HIST1H4H,HNRNPD,IMPACT,LARP4,LARP4B,LARS,LRPPRC,LSM14A,LSM14B,MAP2K1,METTL14,MPV17L2,MTG2,MTOR,MYCN,MYD88,NACC2,NCOR1,NEURL1,NOLC1,NUP133,NUP188,NUP210,NUP214,NUP93,OGFOD1,PA2G4,PABPC1,PDE12,PIWIL1,POLR2A,POLR2E,POLR2K,PRKCA,PRKCD,PRKRA,PSMA1,PSMA5,PSMA6,PSMA7,PSMB2,PSMB7,PSMB8,PSMB9,PSMD11,PSMD12,PSMD14,PSMD2,PSMD6,PSTK,PUM1,PUM2,RAN,RANBP2,RBM4B,RIDA,RMND1,RPL10,RPL5,RPS27L,RPS6KB1,SECISBP2L,SEH1L,SET,SMAD1,SMAD3,SMG7,STAT3,SYNCRIP,TARDBP,TARS2,THRAP3,TNPO1,TNRC6A,TOB1,TPR,TRAP1,TSC1,UBA52,UBB,UCN,UNK,UPF1,UPF3B,UQCC2,XPO1,YBX2,YTHDF1,YWHAZ,ZC3H10,ZC3H12D,ZC3H14,ZC3H7B,ZFP36L2,ZNF540	MammalFishAncestor	86.3817
GO.Biological.Process	GO:0070486	leukocyte.aggregation	353	3.831160e-91	4.948709e-87	1.401901e-89	1.542890e+0	ADAM17,APBB1IP,ATP7A,BATF,CD4,CYLD,DDOST,DLL4,DNAJA3,DOCK8,DPP4,EIF2AK4,F2RL1,FKBP1B,FOXP1,FYN,FZD8,GATA3,GLI3,ICAM1,KIT,LEF1,LEPR,NEDD4,NKAP,PAX1,PIK3CD,PPP3CB,PREX1,PRKDC,PTPN2,RAB27A,RHOH,RORA,SATB1,SHH,SMAD3,SP3,STAT3,STAT5B,STK11,STOML2,TBX21,TCF7,TSC1,WASHC1,ZFP36L2	MammalFishAncestor	86.3055
GO.Biological.Process	GO:0021675	nerve.development	354	6.682335e-91	8.631572e-87	2.438297e-89	1.780454e+0	ATP8B1,DAG1,DICER1,DRGX,ERBB3,GABRB2,GLI3,HOXA1,HOXA3,HOXB1,HOXB2,HOXB3,HOXD3,LRIG2,NAV2,NKX2-2,NRP2,PAX2,PHOX2A,PHOX2B,POU4F1,POU4F3,RNF165,SALL1,SEMA3F,SIX1,SIX4,SLC1A3,SULF1,SULF2,TBX1,TFAP2A,UNC13B	MammalFishAncestor	86.0639
GO.Biological.Process	GO:0021699	cerebellar.cortex.maturation	355	6.918708e-91	8.936895e-87	2.517435e-89	1.028395e+1	RERE	MammalFishAncestor	86.0488
GO.Biological.Process	GO:0002293	alpha-beta.T.cell.differentiation.involved.in.immune.response	356	1.513467e-90	1.954945e-86	5.491419e-89	2.610960e+0	ATP7A,BATF,FOXP1,GATA3,LEF1,RORA,STAT3	MammalFishAncestor	85.7089
GO.Biological.Process	GO:0048625	myoblast.fate.commitment	357	1.937869e-90	2.503145e-86	7.011612e-89	4.428194e+0	PITX1,TCF7L2	MammalFishAncestor	85.6015
GO.Biological.Process	GO:0002292	T.cell.differentiation.involved.in.immune.response	358	4.416035e-90	5.704192e-86	1.593350e-88	2.583933e+0	ATP7A,BATF,FOXP1,GATA3,LEF1,RORA,STAT3,TSC1	MammalFishAncestor	85.2438
GO.Biological.Process	GO:0046364	monosaccharide.biosynthetic.process	359	6.759978e-90	8.731864e-86	2.432274e-88	2.515370e+0	ALDOC,CHST15,CRTC2,ENO1,ENO2,ENSG00000266953,G6PC2,GAPDH,GPD2,GPI,MDH1,PGAM4,PGK1,PGM1,RBP4,SLC25A12,SLC25A13,TKT,TPI1	MammalFishAncestor	85.0589
GO.Biological.Process	GO:0009145	purine.nucleoside.triphosphate.biosynthetic.process	360	9.110080e-90	1.176749e-85	3.268747e-88	2.949797e+0	ADK,AK9,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP5S,ATP6V0A1,ATP6V0A2,IMPDH2,NME4,SLC25A13,STOML2	MammalFishAncestor	84.9293
GO.Biological.Process	GO:0007420	brain.development	361	1.578467e-89	2.038906e-85	5.647939e-88	1.239890e+0	ABCB4,ACAT1,ACSL3,ACTB,AK4,AK8,AKT3,ALDH1A2,ALDH1A3,ANXA3,ARID1A,ARMC4,ARX,ATIC,ATM,ATP7A,ATRX,AXIN1,BAG3,BAIAP2,BARHL1,BBS2,BOK,BPTF,BRCA2,C12orf57,C16orf45,C5AR1,C5orf42,CDK5RAP3,CEP120,CEP290,CHD5,CIC,CLN5,CNP,COL4A1,CRH,CTTNBP2,DCLK1,DCLK2,DCT,DLG5,DLX1,DLX2,DLX5,DNAH5,DOCK7,DPCD,DSCAML1,DYNC2H1,EFNA2,EMX2,EN2,EZH1,FANCC,FAT4,FEZF1,FGF8,FLNA,FOXB1,FOXO3,FOXP2,FYN,FZD6,GDF7,GLI1,GLI2,GLI3,GNAO1,GNB4,GNPAT,GSC,GSK3B,GSX1,GSX2,H3F3B,HERC1,HMX2,HMX3,HNF1B,HNRNPD,HOXB1,HOXB2,HOXB3,HSPG2,HTR5A,IMMP2L,INA,INHBA,IRS2,KAT2A,KDM2B,KDM6B,KIF14,KIF1A,KIF5B,KNDC1,LAMB1,LDB1,LEF1,LHX1,LHX3,LRP1,LRP2,MAP2K1,MAPKAP1,MBP,MDK,MED1,MEN1,METTL14,MKKS,MNAT1,MT3,MTOR,NAGLU,NDE1,NDEL1,NEURL1,NEUROD2,NEUROG3,NF1,NIPBL,NKX2-1,NKX2-2,NODAL,NOTCH1,NR2E1,NR2F2,NR4A2,NR4A3,OGDH,OTP,OTX1,OTX2,PAFAH1B3,PAK1,PAPD4,PAX2,PAX6,PHF8,PHLPP2,PHOX2A,PHOX2B,PITX1,PITX2,PITX3,PLXNB2,POU3F1,POU3F2,POU3F3,POU4F1,POU6F1,PRKDC,PROX1,PTCH1,PTPRG,PTPRS,QARS,RAB18,RAPGEF2,RARB,RELN,RERE,RFX4,RHOA,RIDA,RORA,RPGRIP1L,RTN4,RTN4RL1,SALL1,SALL3,SCN5A,SEC16A,SEMA6D,SETD2,SEZ6,SHH,SIX3,SLC38A3,SLC4A10,SLC6A11,SLC6A17,SLC6A3,SLIT1,SMAD1,SMAD9,SOX2,SPHK1,SPTBN2,STXBP3,SUDS3,SYPL2,SYT1,SZT2,TAF1,TBR1,TCTN1,TMEM57,TOP2B,TSC1,TTBK1,TTC21B,TWSG1,TYRO3,UNCX,UQCRQ,VAX1,WNT2,WNT2B,WNT7A,XRN2,YWHAQ,ZEB2,ZIC1,ZIC2	MammalFishAncestor	84.6906
GO.Biological.Process	GO:0034465	response.to.carbon.monoxide	362	3.903762e-89	5.042489e-85	1.392953e-87	5.650033e+0	KCNMA1	MammalFishAncestor	84.2974
GO.Biological.Process	GO:0043038	amino.acid.activation	363	6.680387e-89	8.629056e-85	2.377150e-87	2.479391e+0	AARS2,AASDH,AIMP1,AIMP2,CARS2,CCDC12,DALRD3,EEF1E1,FARSB,GATB,LARS,MARS,NARS,NARS2,PPA1,PPA2,QARS,TARS2	MammalFishAncestor	84.064
GO.Biological.Process	GO:2001237	negative.regulation.of.extrinsic.apoptotic.signaling.pathway	364	1.496119e-88	1.932537e-84	5.309167e-87	1.796348e+0	ACVR1,AKT1,BIRC6,COL2A1,CSF2,CTTN,EYA1,FASLG,FGA,FGB,FGG,FYN,GCLC,GCLM,GPX1,HTT,ICAM1,ITGA6,MAP2K5,MCL1,PAK5,RAF1,RB1CC1,RNF34,RPS6KB1,SFRP2,SH3RF1,TCF7L2,ZMYND11	MammalFishAncestor	83.7139
GO.Biological.Process	GO:0034249	negative.regulation.of.cellular.amide.metabolic.process	365	2.046563e-88	2.643545e-84	7.242590e-87	1.735343e+0	ABCA7,AGO1,AGO3,AGO4,CIRBP,CNOT7,CNOT9,CPEB2,CPEB3,DDX3X,DGCR8,DICER1,EIF2AK1,EIF2AK4,EIF2S1,EIF4EBP2,EIF4EBP3,ENC1,FXR1,GAPDH,HNRNPD,METTL14,PRKRA,PUM1,PUM2,RAN,RIDA,SMAD1,SMAD3,STAT3,SYNCRIP,TNRC6A,TOB1,TPR,TSC1,UNK,UPF1,ZC3H12D,ZC3H7B,ZFP36L2,ZNF540	MammalFishAncestor	83.5778
GO.Biological.Process	GO:0007034	vacuolar.transport	366	3.229278e-88	4.171258e-84	1.139688e-86	1.908575e+0	AKTIP,ANKFY1,AP1G1,AP3B1,AP3M1,ARSB,CDX2,GCC2,GNPTAB,LAMP1,LAMP2,LARS,LYST,NEDD4,PCDHGA3,PCSK9,PIK3R4,RAB12,RHOB,RILP,SNF8,SORT1,STX8,TMEM106B,VPS33A,VPS39,VPS41,VPS54,VTI1A,VTI1B	MammalFishAncestor	83.3797
GO.Biological.Process	GO:0097531	mast.cell.migration	367	3.346720e-88	4.322958e-84	1.177918e-86	5.668714e+0	CHGA,KIT,PIK3CD,STAT5B	MammalFishAncestor	83.3642
GO.Biological.Process	GO:0001678	cellular.glucose.homeostasis	368	3.910420e-88	5.051090e-84	1.372579e-86	1.932882e+0	ABCC8,ENDOG,FOXO3,GAS6,GCLC,GCLM,GJB6,HK1,HKDC1,ICAM1,IRS2,KCNJ11,MEN1,OGT,PAX2,PDK3,PIK3R2,POLG,PTPRN,PTPRN2,RAB11FIP2,RAF1,RANBP2,RAP1A,SERPINF1,SIN3A,TWNK,UNC13B,ZNF236	MammalFishAncestor	83.2966
GO.Biological.Process	GO:0051146	striated.muscle.cell.differentiation	369	6.470357e-88	8.357760e-84	2.264976e-86	1.545294e+0	ACTA1,ACTC1,ACTG1,ACVR1,ADAM12,ADGRB3,AKT1,ARID1A,BCL9,CAPN3,CASQ1,CHRNB1,DNER,FLNC,GATA6,GPX1,HOMER1,KAT2A,KDM6B,KLHL40,KLHL41,KRT8,LEF1,LMOD2,MEF2C,MTOR,MYBPC1,MYBPC2,MYBPC3,MYBPHL,MYEF2,MYH11,MYH3,MYL2,MYOM1,MYOM2,MYOZ1,MYOZ2,NEXN,NFATC2,NOS1,NPPA,NPPB,OBSCN,OBSL1,P2RX2,PDGFRA,PITX2,PROX1,PROX2,RARB,RYR1,SDC1,SHH,SIX4,SORT1,SOX6,SPAG9,STAC3,TANC1,TCAP,TPM1,TSC1,WFIKKN2,WT1	MammalFishAncestor	83.0779
GO.Biological.Process	GO:0048596	embryonic.camera-type.eye.morphogenesis	370	6.786709e-88	8.766392e-84	2.369295e-86	2.314322e+0	ALDH1A3,ARID1A,KDM2B,PAX2,PAX6,PROX1,SIX3,SP3,TBX2,TFAP2A,ZEB1	MammalFishAncestor	83.0572
GO.Biological.Process	GO:0016477	cell.migration	371	1.296594e-87	1.674810e-83	4.514314e-86	1.237364e+0	ABCC1,ACVR1,ADAM17,AGTR1,AIMP1,ANKS1A,APCDD1,APOB,ARF4,ARHGEF16,ARPC5L,ARSB,ARX,ATP5B,AUTS2,AZU1,BAMBI,BARHL1,BARHL2,BIN2,C16orf45,C5AR1,CALCA,CCL20,CD248,CDKL5,CENPV,CHGA,COL1A1,COL1A2,CORO1C,CSF3R,CSPG4,CTHRC1,CTTN,CXCR5,CYP7B1,DAPK2,DCLK1,DGKZ,DMRT1,DNAAF4,DNER,DOCK1,DOCK4,DOCK8,DPP4,DRGX,EDNRB,ELANE,EMX2,ENPEP,EPHA4,F2RL1,FAP,FAT2,FEZF1,FGF8,FLNA,FLT1,FN1,FOLR1,FOXB1,FSCN1,FSCN2,FYN,GAS6,GATA3,GBF1,GCNT1,GLI3,GPX1,GRB14,GYPA,GYPB,HCK,HEXB,HOXA5,HOXB9,HRH1,ICAM1,ITGA6,ITGB1BP1,JAK1,JUP,KALRN,KDR,KIT,KITLG,LAMB1,LAMC1,LEF1,LHX1,LRP12,LURAP1,LYST,MATN2,MCOLN2,MDK,MEF2C,MEGF8,MYO18A,NAV1,NDE1,NDEL1,NFATC2,NKX2-1,NKX6-1,NODAL,NOTCH1,NOV,NOX1,NR2E1,NR2F2,NR4A2,NRCAM,NTN1,NUP188,NUP93,OGDH,P2RY12,PAK5,PAK6,PALLD,PARVA,PAX6,PDGFRA,PHOX2B,PIK3CB,PIK3CD,PIK3R2,PITX2,PKN2,PKN3,PLCG1,PLPP1,PLXNB3,PLXND1,POU3F2,POU3F3,POU4F1,PPIA,PPP1R9B,PREX1,PRKCD,PRKCQ,PRKCZ,PROX1,PRTN3,PSTPIP2,PTK6,PTPN6,PTPRF,RAPGEF2,RELN,RERE,RHOA,ROCK1,RPS6KB1,RTN4,SDC1,SDC3,SDCCAG8,SELPLG,SEMA3F,SETD2,SHH,SHTN1,SIX1,SIX2,SIX3,SIX4,SLC16A3,SOX18,SPNS2,STARD13,STAT5B,TBX1,TBX21,TGFBR3,THBS4,TMEM201,TNFRSF11A,TNFSF11,TNFSF12,TNK1,TOP2B,TSPAN1,TYK2,TYRO3,UNK,USP33,USP9X,USP9Y,VAX1,WDPCP,WNT7A,WWC1,ZEB2,ZRANB1	MammalFishAncestor	82.776
GO.Biological.Process	GO:0001658	branching.involved.in.ureteric.bud.morphogenesis	372	1.668356e-87	2.155015e-83	5.793052e-86	1.885393e+0	ADAMTS16,CTNNBIP1,EYA1,FAT4,FGF8,FOXD1,GLI3,HOXA11,HOXD11,LHX1,NPNT,PAX2,PGF,PKD2,PTCH1,SALL1,SHH,SIX1,WT1	MammalFishAncestor	82.6665
GO.Biological.Process	GO:0002181	cytoplasmic.translation	373	1.779289e-87	2.298308e-83	6.161683e-86	3.304120e+0	DENR,EIF3M,EIF4G1,MCTS1,PTBP1,RPL22,RPL27A,RPL30,RPL4,RPL9,RPLP1,RPS3A,SSB	MammalFishAncestor	82.6386
GO.Biological.Process	GO:0006884	cell.volume.homeostasis	374	2.069119e-87	2.672681e-83	7.146206e-86	3.494071e+0	CLCN6,KCNMA1,LRRC8A,SLC12A2,TRPV4	MammalFishAncestor	82.5731
GO.Biological.Process	GO:0034660	ncRNA.metabolic.process	375	2.169603e-87	2.802476e-83	7.473270e-86	1.458012e+0	AARS2,AGO1,AGO3,AGO4,AIMP1,AIMP2,ASZ1,CARS2,CAVIN1,CCDC12,CCNT1,CPSF1,CSNK1D,CSTF2,CTU2,DALRD3,DCAF13,DDX1,DDX51,DDX52,DGCR8,DICER1,DIS3,DIS3L,EEF1E1,ELL,ELP4,ELP5,ELP6,EMG1,ENSG00000203546,EXOSC10,EXOSC8,FARSB,FCF1,GATB,GTF2A2,GTF2B,GTF3A,GTF3C4,GTF3C5,GTF3C6,HENMT1,HSD17B10,ICE1,ICE2,IMP3,INTS1,INTS12,INTS14,INTS2,INTS7,KIAA0391,KRR1,LARS,LSM6,MARS,MDN1,MRM1,MRPS9,MYBL1,NABP2,NARS,NARS2,NOL11,NOLC1,NOP2,NPM3,NSA2,PA2G4,PAPD5,PDCD11,PIWIL1,POLR2A,POLR2E,POLR2K,POP1,PPA1,PPA2,PRKRA,PSTK,PUS1,QARS,QTRT2,RAN,RNF113A,RNF113B,RPAP2,RPF1,RPF2,RPL10,RPL19,RPL21,RPL22,RPL27A,RPL30,RPL32,RPL35,RPL39,RPL4,RPL41,RPL5,RPL9,RPLP1,RPRD2,RPS10,RPS15,RPS2,RPS26,RPS3A,RRS1,SKIV2L2,SMAD1,SMAD3,SNAPC4,SNAPC5,SSB,TAF11,TAF1B,TAF5,TARS2,TBL3,TDRD1,TEX10,TFB1M,TRDMT1,TRMT1,TRMT2B,TRMT5,TRMT61A,UBA52,UTP11,UTP15,UTP20,UTP6,WDR12,WDR18,WDR3,WDR37,XRN2,ZNF143	MammalFishAncestor	82.5525
GO.Biological.Process	GO:0007227	signal.transduction.downstream.of.smoothened	376	6.453536e-87	8.336032e-83	2.217030e-85	6.378870e+0	IFT122,SHH	MammalFishAncestor	82.079
GO.Biological.Process	GO:0030177	positive.regulation.of.Wnt.signaling.pathway	377	1.037143e-86	1.339678e-82	3.553522e-85	1.602448e+0	ANKRD6,AXIN1,BAMBI,COL1A1,CSNK1D,CTDNEP1,DDX3X,DKK2,DLX5,DVL2,FAM53B,JUP,KANK1,LRRK1,MACF1,NKD1,NRARP,PPM1A,PSMA1,PSMA5,PSMA6,PSMA7,PSMB2,PSMB7,PSMB8,PSMB9,PSMD11,PSMD12,PSMD14,PSMD2,PSMD6,SALL1,SFRP2,SHH,SMARCA4,SULF1,SULF2,TMEM198,UBA52,UBB,UBR5,WNT2,WNT2B,WNT7A,ZEB2,ZRANB1	MammalFishAncestor	81.873
GO.Biological.Process	GO:0021695	cerebellar.cortex.development	378	1.798303e-86	2.322868e-82	6.145153e-85	2.089138e+0	ATP7A,GLI1,GLI2,HERC1,KIF14,KNDC1,LDB1,LHX1,MAP2K1,MDK,NAGLU,NEUROD2,OGDH,PROX1,RERE,RFX4,RORA,SEZ6,SPTBN2,UQCRQ,WNT7A	MammalFishAncestor	81.634
GO.Biological.Process	GO:0006309	apoptotic.DNA.fragmentation	379	2.534010e-86	3.273181e-82	8.636361e-85	4.365922e+0	DICER1,DNASE1L3,DNASE2B,ENDOG,FOXL2	MammalFishAncestor	81.485
GO.Biological.Process	GO:2000729	positive.regulation.of.mesenchymal.cell.proliferation.involved.in.ureter.development	380	2.731724e-86	3.528568e-82	9.285705e-85	6.245553e+0	SHH,SIX1	MammalFishAncestor	81.4524
GO.Biological.Process	GO:0072358	cardiovascular.system.development	381	2.980687e-86	3.850153e-82	1.010539e-84	1.294458e+0	ACVR1,ADAMTS9,ADIPOR2,ADM,AIMP1,AKT1,ALDH1A2,ANGPTL3,ANGPTL6,ANXA2,APOB,ARHGAP22,ARHGAP24,ARID1A,ATP5B,ATP7A,BCAS3,C5orf42,CDX2,CLIC4,COL1A1,COL1A2,COL4A1,COL4A2,CRKL,CSPG4,DAG1,DDIT3,DLL4,DYNC2H1,ECM1,EDNRA,ELK3,ENPEP,EYA1,FAP,FGF8,FLT1,FN1,FOLR1,FZD8,GATA6,GJA5,GLI3,GLMN,GPI,GPX1,HOXA1,HOXA3,HOXA7,HOXB13,HOXB3,HPSE,HSPG2,HTATIP2,IMMP2L,ITGB1BP1,JAG1,KDR,KLF5,LEF1,LEPR,LRP1,LRP2,LTBP1,MAP2K1,MED1,MEF2C,MEGF8,MEIS1,MIB1,MMP2,MMP21,MYO1E,NDUFS6,NEDD4,NF1,NODAL,NOTCH1,NOV,NOX1,NR2F2,NRARP,NRCAM,NRP2,OTULIN,PARVA,PAX6,PCSK5,PDE3B,PDGFRA,PGF,PIK3CB,PIK3R6,PITX2,PKD1,PKD2,PLCD1,PLXND1,POFUT1,PPP3CB,PRKCA,PRKD2,PROK1,PROK2,PROX1,PROX2,PTGS2,PTPN14,RAPGEF2,RASA1,RBM15,RHOB,RNF213,RORA,SERPINF2,SETD2,SFRP2,SHH,SIX1,SMAD6,SOX18,SPHK1,STK11,TBX1,TBX2,TBX4,TCF7L2,TGFBR3,TNFSF12,VASH1,WDPCP,WNT2,WNT7A,WT1,ZFPM2,ZNF304	MammalFishAncestor	81.4145
GO.Biological.Process	GO:0070328	triglyceride.homeostasis	382	4.859727e-86	6.277309e-82	1.643275e-84	3.229810e+0	ANGPTL3,ANGPTL8,LIPC,MED13,RORA	MammalFishAncestor	81.2022
GO.Biological.Process	GO:0048496	maintenance.of.animal.organ.identity	383	3.276265e-85	4.231952e-81	1.104948e-83	4.090097e+0	ADGRV1,NPHP3,USH2A	MammalFishAncestor	80.3735
GO.Biological.Process	GO:0043583	ear.development	384	5.390461e-85	6.962858e-81	1.813244e-83	1.424395e+0	ALDH1A3,ATP8B1,CDH23,CEBPD,CEP290,CHRNA9,COL11A1,COL2A1,CTHRC1,DLX5,DLX6,DVL2,ECE1,ESRRB,EYA1,FAT4,FGF20,FGF8,FREM2,FZD6,GABRB2,GATA3,GJB2,GJB6,GLI2,GLI3,GSC,HMX2,HMX3,HOXA1,INSIG1,JAG1,LHX3,LIN7A,LRTOMT,MYO15A,MYO3A,MYO3B,MYO7A,NAGLU,NIPBL,NOTCH1,NR4A3,NTN1,OSR2,OTX1,PAX2,PDZD7,PHOX2B,POU4F3,PRKRA,PROX1,ROR1,RPGRIP1L,SALL1,SHH,SIX1,SIX2,SIX4,SLC26A5,SLC44A4,SOX2,SPARC,STOX1,TBX1,TCAP,TFAP2A,TGFB3,TSHZ1,USH1C,USH2A,WDPCP,WDR19,ZEB1,ZIC1	MammalFishAncestor	80.1572
GO.Biological.Process	GO:0008154	actin.polymerization.or.depolymerization	385	8.710870e-85	1.125183e-80	2.922553e-83	2.443882e+0	ABI1,COBLL1,CORO7,CTTN,DIAPH1,LMOD2,MICAL2,MICALL2,MSRB1,PREX1,VIL1,WASF1,WASF3,WASL,WIPF1	MammalFishAncestor	79.9488
GO.Biological.Process	GO:1904209	positive.regulation.of.chemokine.(C-C.motif).ligand.2.secretion	386	1.058186e-84	1.366859e-80	3.541085e-83	6.967981e+0	MBP,POSTN	MammalFishAncestor	79.8643
GO.Biological.Process	GO:0051152	positive.regulation.of.smooth.muscle.cell.differentiation	387	1.193028e-84	1.541034e-80	3.982001e-83	3.430442e+0	KIT,PIAS1,SHH,SMARCD3	MammalFishAncestor	79.8122
GO.Biological.Process	GO:1903533	regulation.of.protein.targeting	388	1.451194e-84	1.874507e-80	4.831204e-83	1.460949e+0	ACTL6A,ANK3,ARIH2,BAG3,BAMBI,BAP1,BMP6,CCDC22,CTSK,CYLD,DACT3,DPH6,EDAR,EFCAB7,EMD,F2R,FLNA,FYN,GAS6,GLI3,GLS2,GPR26,GSK3B,HUWE1,HYAL2,ITGB1BP1,JUP,KANK1,KAT2A,KEAP1,LRRC46,MDFIC,MED1,MFF,MICALL2,MIEF2,MTCL1,MTOR,MXI1,MYBPC1,NBPF3,NF1,NFKBIA,NFKBIE,NKAP,NODAL,NOV,NUP93,OSCP1,PAK1,PDCD5,PIK3R2,PKD1,PKD2,PLAGL2,PPM1A,PPM1B,PRKCD,PSMB7,PTGS2,RAB23,RHOA,SAE1,SFRP2,SHH,SLC17A9,SMAD3,SPHK1,SREBF1,SRI,STARD7,SULF2,TGFB3,TLR7,TMSB4X,TPR,UBL4B,UBR5,ZBTB17,ZIC1	MammalFishAncestor	79.7271
GO.Biological.Process	GO:0009416	response.to.light.stimulus	389	1.608029e-84	2.077091e-80	5.339566e-83	1.500078e+0	AANAT,ABCA4,ABCC8,AKT1,ATP1A2,BHLHE40,BMF,BRCA2,CACNA1F,CACNA2D4,CIRBP,CLOCK,CRTC1,CUL4B,DRD3,DTL,EIF2AK4,EIF2S1,ELANE,EP300,ERCC2,ERCC6,FBXL3,FECH,FOS,FOXB1,GJA10,GNAT1,GNAT2,GNB1,GPX1,GRK1,HMGCR,HOXA1,HRH1,HYAL1,HYAL2,HYAL3,ID2,IMPACT,INO80,JUND,KIT,KMT2A,MAPK10,MAPK8,MEIS2,MEN1,MSH6,MTOR,NEDD4,NF1,NLGN3,NMU,NPS,NR2E3,PAPD4,PDC,PDE6C,PDE6G,PIAS1,POLG,POLK,PPID,PPP1CC,PPP1R1B,PTGS2,RBM4B,RHO,RS1,SEMA5B,SLC1A3,SLC24A1,SLC4A10,STK11,TAF1,TANC1,TIPIN,TMEM161A,TP53I13,TP73,UBE2A,UBE2B,UBE4B,USP1,USP47	MammalFishAncestor	79.6825
GO.Biological.Process	GO:0006605	protein.targeting	390	1.692009e-84	2.185568e-80	5.604021e-83	1.442384e+0	AKAP12,AKAP6,AKT1,AP3B1,AP3M1,AP4S1,ATG4B,ATG4C,CACNG3,CDC37,CSE1L,DAG1,DNAJC19,DNLZ,ERBIN,FAM53B,GABARAP,GCC2,GNPTAB,GPN3,GRPEL1,HEATR3,HSP90AA1,HSPA4,ICMT,IMMP1L,IMMP2L,IPO9,KPNA2,KPNA4,LAMP2,LARS,LTBP2,MFF,MFN2,MT3,MTX2,MTX3,NCKIPSD,NDUFA13,NEDD4,NFKBIA,NUP133,NUP188,NUP214,PACS1,PAM16,PAN3,PARD3,PEX14,PEX2,PEX5,PEX5L,PHB2,PIK3R4,PMM1,PMPCA,RAB27A,RAN,RANBP1,RANBP2,RERE,RPL10,RPL19,RPL21,RPL22,RPL27A,RPL30,RPL32,RPL35,RPL39,RPL4,RPL41,RPL5,RPL9,RPLP1,RPS10,RPS15,RPS2,RPS26,RPS3A,SEC63,SIX2,SIX3,SNF8,SNUPN,SPTBN1,SRP14,SRP54,SRP68,SRP72,STAT3,TNPO1,TNPO3,TOB1,TOMM20,TPR,TRAM1,TSC2,UBA52,VPS41,VTI1A,VTI1B,YWHAQ,YWHAZ,ZFYVE9	MammalFishAncestor	79.6604
GO.Biological.Process	GO:0034101	erythrocyte.homeostasis	391	2.481497e-84	3.205350e-80	8.197825e-83	2.049472e+0	AMPD3,ERCC2,GATA3,GPI,HOXB6,INHA,INHBA,KIT,MED1,NFE2L1,PTPN2,SLC11A2,SOX6,SP3,TGFBR3	MammalFishAncestor	79.4941
GO.Biological.Process	GO:0097194	execution.phase.of.apoptosis	392	3.351305e-84	4.328881e-80	1.104306e-82	2.329223e+0	ACVR1C,AKT1,BCAP31,BOK,CASP7,CDK5RAP3,CLSPN,DICER1,DNASE1L3,DNASE2B,ENDOG,FOXL2,MADD,PRKCD,PRKCQ,ROCK1,SATB1,STK24,TAOK1	MammalFishAncestor	79.3636
GO.Biological.Process	GO:0035585	calcium-mediated.signaling.using.extracellular.calcium.source	393	4.382686e-84	5.661116e-80	1.440487e-82	8.035029e+0	CACNA1C	MammalFishAncestor	79.2471
GO.Biological.Process	GO:0030111	regulation.of.Wnt.signaling.pathway	394	4.420967e-84	5.710563e-80	1.449381e-82	1.386651e+0	ANKRD10,ANKRD6,APCDD1,AXIN1,BAMBI,BTRC,CCNY,COL1A1,CSNK1D,CTDNEP1,CTHRC1,CTNNBIP1,CYLD,DACT3,DDIT3,DDX3X,DKK2,DKK3,DLX5,DVL2,EMD,ESR1,FAM53B,FOLR1,FOXO3,FZD6,G3BP1,GLI1,GLI3,GSC,GSK3B,HNF1B,IGFBP6,INVS,JUP,KANK1,KLHL12,LATS2,LEF1,LRP1,LRRK1,LZTS2,MACF1,MDFIC,MED12,NFATC1,NKD1,NOTCH1,NPHP3,NRARP,PPM1A,PPP2CA,PSMA1,PSMA5,PSMA6,PSMA7,PSMB2,PSMB7,PSMB8,PSMB9,PSMD11,PSMD12,PSMD14,PSMD2,PSMD6,RBX1,RNF213,SALL1,SFRP2,SHH,SHISA2,SIX3,SMARCA4,SNX3,SOX2,STK11,STK3,SULF1,SULF2,TCF7L2,TMEM198,TMEM88,TSC2,UBA52,UBB,UBR5,WNT2,WNT2B,WNT5B,WNT7A,ZEB2,ZRANB1	MammalFishAncestor	79.2433
GO.Biological.Process	GO:0051225	spindle.assembly	395	6.620752e-84	8.552025e-80	2.165070e-82	2.286947e+0	ABRAXAS2,ARHGEF10,BCCIP,CEP192,CLASP1,CSNK1D,FLNA,HAUS1,INO80,KIF23,KIF3B,MZT1,NCOR1,NEK2,NEK6,NEK7,NUMA1,PIBF1,RAB11A,RHOA,SPICE1,TUBGCP4,TUBGCP5,TUBGCP6,WASHC1,WRAP73,ZNF207	MammalFishAncestor	79.0679
GO.Biological.Process	GO:0042063	gliogenesis	396	7.776420e-84	1.004480e-79	2.536566e-82	1.469222e+0	ADAM22,AKT1,APCDD1,ARHGEF10,AZU1,BOK,C16orf45,CNP,CNTNAP1,CSPG4,DAG1,DICER1,DNER,EIF2B2,EPHA4,ERBB3,ERCC2,FGF5,GCM1,GLI3,GPR157,HDAC10,HDAC11,HEXB,LAMA2,LAMB1,LAMB2,LEF1,LRP1,MAP2K1,MATN2,MED12,METTL14,MPP5,MT3,MYOC,NAB1,NF1,NKX2-1,NKX2-2,NKX6-1,NKX6-2,NLGN3,NOTCH1,NR2E1,P2RY12,PARD3,PAX2,PAX6,PHOX2B,POU3F1,POU3F2,PRDM8,PTPRZ1,RELN,ROR1,RTN4,SHH,SOX2,SOX6,STAT3,TENM4,TRPC4,WASF3	MammalFishAncestor	78.9981
GO.Biological.Process	GO:0032467	positive.regulation.of.cytokinesis	397	8.895977e-84	1.149093e-79	2.894442e-82	2.621922e+0	CENPV,CIT,CSPP1,CXCR5,DRD3,KIF14,KIF23,KIF3B,PKN2,PKP4,RHOA	MammalFishAncestor	78.9396
GO.Biological.Process	GO:0031023	microtubule.organizing.center.organization	398	1.590711e-83	2.054721e-79	5.162617e-82	2.025425e+0	ARHGEF10,BCAS3,BRCA2,CEP120,CEP135,CEP152,CEP192,CETN3,CHD3,CLASP1,CNTLN,GCC2,HAUS1,KIF3A,KIF3B,NDE1,NDEL1,NEK2,NIN,ODF2,PKD2,SDCCAG8,SSX2IP,TUBE1,TUBGCP4,TUBGCP5,TUBGCP6,USP33	MammalFishAncestor	78.6872
GO.Biological.Process	GO:0006754	ATP.biosynthetic.process	399	2.055394e-83	2.654952e-79	6.654016e-82	3.238996e+0	AK9,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP5S,ATP6V0A1,ATP6V0A2,SLC25A13,STOML2	MammalFishAncestor	78.5759
GO.Biological.Process	GO:0014044	Schwann.cell.development	400	3.416653e-83	4.413291e-79	1.103323e-81	2.755179e+0	ADAM22,AKT1,ARHGEF10,CNTNAP1,DAG1,DICER1,LAMB2,MED12,MPP5,MYOC,NF1,PARD3,POU3F1,POU3F2	MammalFishAncestor	78.3552
GO.Biological.Process	GO:0032383	regulation.of.intracellular.cholesterol.transport	401	3.847830e-83	4.970242e-79	1.239462e-81	5.586411e+0	ANXA2,ARV1,LDLRAP1,PCSK9	MammalFishAncestor	78.3036
GO.Biological.Process	GO:0050953	sensory.perception.of.light.stimulus	402	3.856566e-83	4.981526e-79	1.239186e-81	1.533270e+0	ABCA4,ABCC6,ADGRV1,ATXN7,BBS10,BBS2,BBS5,CACNA1F,CACNA2D4,CDH23,COL11A1,COL1A1,COL2A1,CRYBA1,CRYGA,CRYGB,CRYGC,CRYGD,DHRS3,DLL4,DNAJC19,FAM161A,FSCN2,GJA10,GJA3,GJA8,GJD2,GLRA1,GLRB,GNAT1,GNAT2,GRK1,HMCN1,IMPG1,IRX5,LAMB2,MIP,MKKS,MYO3A,MYO3B,MYO5A,MYO7A,MYO9A,NR2E1,NR2E3,NYX,OAT,OCLM,PAX2,PAX6,PDC,PDE6C,PDE6G,POU4F3,POU6F2,RBP4,RDH12,RHO,RS1,SEMA5B,SIX3,SIX6,SLC24A1,USH1C,USH2A,ZIC2	MammalFishAncestor	78.3026
GO.Biological.Process	GO:0010694	positive.regulation.of.alkaline.phosphatase.activity	403	4.110167e-83	5.309103e-79	1.317395e-81	3.806667e+0	MEF2C,NPNT,SMAD3	MammalFishAncestor	78.275
GO.Biological.Process	GO:0072539	T-helper.17.cell.differentiation	404	5.125414e-83	6.620497e-79	1.638737e-81	4.545892e+0	BATF,RORA,STAT3	MammalFishAncestor	78.1791
GO.Biological.Process	GO:0006623	protein.targeting.to.vacuole	405	5.869402e-83	7.581507e-79	1.871977e-81	2.876426e+0	AP3B1,AP3M1,GCC2,GNPTAB,LAMP2,LARS,NEDD4,PIK3R4,SNF8,VPS41,VTI1A,VTI1B	MammalFishAncestor	78.1202
GO.Biological.Process	GO:0010909	positive.regulation.of.heparan.sulfate.proteoglycan.biosynthetic.process	406	2.034026e-82	2.627351e-78	6.471309e-81	4.183932e+0	TCF7L2	MammalFishAncestor	77.5805
GO.Biological.Process	GO:0009259	ribonucleotide.metabolic.process	407	2.052813e-82	2.651619e-78	6.515033e-81	1.445868e+0	ACAT1,ACLY,ADCY5,ADCY6,ADCY7,ADCY9,ADK,ADM,ADSS,ADSSL1,AFG1L,AK4,AK5,AK9,ALDOC,AMPD2,AMPD3,APRT,ATIC,ATP1A2,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP5S,ATP6V0A1,ATP6V0A2,ATP6V1A,COX6C,COX7B,COX8C,CROT,DLD,DLG4,ENO1,ENO2,ENO4,ENSG00000266953,GALK1,GAPDH,GNAI3,GPHN,GPI,HK1,HKDC1,HMGCR,IMPDH2,MAGI3,MBIP,MFN1,MYH3,MYH4,MYH8,NADK,NDUFA1,NDUFA12,NDUFA13,NDUFA5,NDUFAF7,NDUFB10,NDUFB5,NDUFS1,NDUFS6,NDUFS7,NDUFV2,NME4,NMNAT1,NPPA,NPPB,NT5C2,NT5E,NUDT3,OGDH,OLA1,PAICS,PAPSS1,PDE3B,PDE4A,PDE4C,PDE7A,PDE8B,PFKM,PGAM4,PGK1,PGM1,PPAT,PRPS2,RAB23,RFK,RORA,SLC25A13,SLC35B2,SLC35B3,STOML2,SULT6B1,TAZ,TPI1,UCKL1,UCN2,UMPS,UPP2,UQCRHL,UQCRQ	MammalFishAncestor	77.5765
GO.Biological.Process	GO:0002366	leukocyte.activation.involved.in.immune.response	408	2.275725e-82	2.939554e-78	7.204789e-81	1.376350e+0	ACAA1,ACLY,ADAM10,ALDOC,AMPD3,ANXA2,ANXA3,APBB1IP,APEH,APRT,ARHGAP45,ARHGAP9,ARSA,ARSB,ATG7,ATP11B,ATP6V0A1,ATP6V1D,ATP7A,AZU1,BATF,BIN2,BRI3,C5AR1,CD180,CD40LG,CDH17,CEP290,CFD,CHGA,CNN2,COPB1,CPNE1,CTSS,CYFIP1,DDOST,DDX3X,DIAPH1,DNAJC13,DNAJC3,DNAJC5,DYNC1H1,EIF2AK4,ELANE,ERP44,F2RL1,FOLR3,FOXP1,GALNS,GATA3,GCA,GHDC,GPI,GPR84,HEXB,HPSE,HSP90AA1,HUWE1,HVCN1,ICAM1,IDH1,IMPDH2,IQGAP2,JUP,KCNAB2,KIT,LAMP1,LAMP2,LAMTOR1,LEF1,LPCAT1,LTA4H,MAGT1,METTL7A,MSH6,NEU1,NR4A3,P2RX1,PA2G4,PGM1,PIK3CD,PKP1,PLAC8,PLCL2,PPIA,PRKCD,PRTN3,PSMA5,PSMB7,PSMD11,PSMD12,PSMD14,PSMD2,PSMD6,PTPN6,PTPRN2,PYGL,QSOX1,RAB10,RAB18,RAB27A,RAB3A,RAB5C,RAP1A,RHOA,RHOF,ROCK1,RORA,SBNO2,SCAMP1,SERPINA3,SLC2A5,SNAP23,SNAP25,SNAP29,SPTAN1,SRP14,STAT3,STXBP3,SWAP70,TMEM30A,TSC1,TUBB4B,TXNDC5,UBR4,UNC13D,VCL	MammalFishAncestor	77.5317
GO.Biological.Process	GO:0009152	purine.ribonucleotide.biosynthetic.process	409	5.093671e-82	6.579495e-78	1.608678e-80	1.877095e+0	ACAT1,ADCY5,ADCY6,ADCY7,ADCY9,ADK,ADM,ADSS,ADSSL1,AK5,AK9,AMPD2,AMPD3,APRT,ATIC,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP5S,ATP6V0A1,ATP6V0A2,IMPDH2,NME4,NPPA,NPPB,PAICS,PAPSS1,PPAT,PRPS2,SLC25A13,SLC35B2,SLC35B3,STOML2,UCN2	MammalFishAncestor	77.1818
GO.Biological.Process	GO:0051151	negative.regulation.of.smooth.muscle.cell.differentiation	410	6.591190e-82	8.513840e-78	2.076546e-80	3.862895e+0	PDCD4,PRDM6,SHH	MammalFishAncestor	77.0699
GO.Biological.Process	GO:0032916	positive.regulation.of.transforming.growth.factor.beta3.production	411	6.598254e-82	8.522965e-78	2.073714e-80	7.190505e+0	SMAD3	MammalFishAncestor	77.0694
GO.Biological.Process	GO:0090596	sensory.organ.morphogenesis	412	6.933316e-82	8.955764e-78	2.173729e-80	1.376994e+0	ALDH1A3,ARID1A,AXIN1,C12orf57,CEP290,CHRNA9,COL11A1,COL2A1,CRB1,CRYGB,CTHRC1,DLX5,DLX6,DVL2,EYA1,FASLG,FBN1,FBN2,FGF8,FOXL2,FOXN4,FSCN2,FZD6,GATA3,GJB6,GLI2,GLI3,GNAT1,GNAT2,GSC,HMX2,HMX3,HOXA1,HOXC13,IFT122,INSIG1,IRX5,JAG1,KDM2B,LHX1,MEGF11,MEIS1,MFN2,MYO15A,MYO3A,MYO3B,MYO7A,NAGLU,NF1,NIPBL,NKD1,NR2E3,NR4A3,NTN1,OSR2,OTX1,PAX2,PAX6,PDE6C,PDZD7,PITX2,PITX3,POU4F3,PRKRA,PROX1,PROX2,RARB,RBP4,RS1,SALL1,SDK1,SDK2,SIX1,SIX2,SIX3,SIX4,SLC44A4,SP3,STAT3,TBX1,TBX2,TCAP,TENM3,TFAP2A,TSHZ1,USH1C,WDPCP,WDR19,WNT2,WNT2B,ZEB1,ZIC1	MammalFishAncestor	77.0479
GO.Biological.Process	GO:0046785	microtubule.polymerization	413	9.183783e-82	1.186269e-77	2.872323e-80	2.846284e+0	AKAP9,CLASP1,CSNK1D,HDGFL3,MAP7D3,MZT1,NDE1,NDEL1,NIN,SLAIN2,TRPV4,TUBG1,TUBG2,TUBGCP4,TUBGCP5,TUBGCP6,ZNF207	MammalFishAncestor	76.9258
GO.Biological.Process	GO:1902869	regulation.of.amacrine.cell.differentiation	414	9.978545e-82	1.288929e-77	3.113354e-80	6.032744e+0	DLX1,DLX2,POU4F2	MammalFishAncestor	76.8898
GO.Biological.Process	GO:0006463	steroid.hormone.receptor.complex.assembly	415	1.424100e-81	1.839510e-77	4.432554e-80	8.442200e+0	FKBP4	MammalFishAncestor	76.7353
GO.Biological.Process	GO:0002551	mast.cell.chemotaxis	416	1.625731e-81	2.099957e-77	5.047973e-80	5.582118e+0	CHGA,KIT,PIK3CD	MammalFishAncestor	76.6778
GO.Biological.Process	GO:2001234	negative.regulation.of.apoptotic.signaling.pathway	417	2.084592e-81	2.692667e-77	6.457236e-80	1.563145e+0	ACVR1,AKT1,BAG5,BCL2L10,BIRC6,BOK,COL2A1,CSF2,CTTN,DDX3X,ENO1,EYA1,FASLG,FGA,FGB,FGG,FYN,GCLC,GCLM,GPX1,HTT,ICAM1,ITGA6,IVNS1ABP,MAP2K5,MCL1,MEIS3,NDUFA13,NFE2L2,NONO,NR4A2,PAK5,PDX1,PTGS2,QARS,RAF1,RB1CC1,RNF34,RPS6KB1,RRM2B,SELENOS,SFRP2,SH3RF1,TCF7L2,TMEM161A,TRAP1,TXNDC12,URI1,USP47,VDAC2,ZMYND11	MammalFishAncestor	76.5698
GO.Biological.Process	GO:0030325	adrenal.gland.development	418	2.175722e-81	2.810380e-77	6.723397e-80	2.408115e+0	CRH,DKK3,INSM1,MDK,NF1,NR5A1,PDGFRA,SALL1,WT1	MammalFishAncestor	76.5512
GO.Biological.Process	GO:0032782	bile.acid.secretion	419	2.176847e-81	2.811833e-77	6.710819e-80	6.272915e+0	ABCB11,ABCB4,ABCC3,AQP9	MammalFishAncestor	76.551
GO.Biological.Process	GO:0071705	nitrogen.compound.transport	420	3.756217e-81	4.851905e-77	1.155216e-79	1.366812e+0	ABCA1,ABCA7,ABCB1,ABCB4,ABCB7,ABCB9,ABCC1,ABCG2,AGFG1,ALKBH5,AQP9,ATP11B,ATP8B1,C2orf83,CADPS,CALHM1,CD320,CDC40,CDH17,CHRM5,COL4A3BP,CPSF1,CPSF3,CSF2,CUBN,DHX9,EIF5A,EIF5A2,ENY2,FKBP1B,FLVCR2,FOLR1,FOLR2,FOLR3,GJB1,GLE1,GLS,GLS2,GPN3,HNF1B,HNRNPA1,HNRNPA3,KIF5C,LMBRD1,LRP2,LRPPRC,MMAA,MYO5A,NCBP3,NF1,NFKBIE,NISCH,NUP133,NUP188,NUP210,NUP214,NUP93,OCA2,P2RX1,PCLO,PDX1,PPFIA1,PPFIA2,PTPRN,PTPRN2,RAB11FIP2,RAB3A,RAF1,RAN,RANBP1,RANBP2,RAPGEF4,RHCE,RHCG,RHD,RIMS2,SEH1L,SERINC5,SIDT1,SLC12A2,SLC15A1,SLC16A10,SLC16A2,SLC18A2,SLC19A3,SLC1A3,SLC1A5,SLC22A13,SLC22A16,SLC22A4,SLC25A12,SLC25A13,SLC25A17,SLC25A2,SLC25A20,SLC25A32,SLC25A4,SLC25A42,SLC29A4,SLC35B2,SLC35B3,SLC36A1,SLC38A10,SLC38A11,SLC38A3,SLC38A6,SLC3A1,SLC43A2,SLC44A4,SLC6A1,SLC6A11,SLC6A17,SLC6A2,SLC6A3,SLC6A5,SLC7A2,SMG7,SNAP23,SNAP25,SNUPN,SRRM1,SSB,STXBP3,SUPT6H,SYT1,TACR2,TAF7,TAP1,THOC2,THOC7,TMEM30A,TOMM20,TPR,TRPC4,TRPV4,TSC1,UNC13B,UPF1,UPF3B,XPO1	MammalFishAncestor	76.3141
GO.Biological.Process	GO:0060993	kidney.morphogenesis	421	6.224337e-81	8.039976e-77	1.909733e-79	1.609983e+0	ADAMTS16,CTNNBIP1,EYA1,FAT4,FGF8,FOXD1,FRAS1,GATA3,GCNT1,GCNT3,GLI3,HNF1B,HOXA11,HOXD11,IRX1,IRX2,IRX3,LHX1,NPHP3,NPNT,PAX2,PGF,PKD1,PKD2,PTCH1,SALL1,SHH,SIX1,SIX2,WT1	MammalFishAncestor	76.0947
GO.Biological.Process	GO:0006857	oligopeptide.transport	422	8.603277e-81	1.111285e-76	2.633377e-79	4.874103e+0	ABCB9,ABCC1,CDH17,SLC15A1	MammalFishAncestor	75.9542
GO.Biological.Process	GO:0001578	microtubule.bundle.formation	423	1.110069e-80	1.433876e-76	3.389778e-79	2.016379e+0	ARMC4,BBS2,CC2D2A,CCDC39,CCDC63,CFAP46,CFAP74,CLASP1,CLIP1,DNAAF4,DNAH1,DNAH5,DNAH7,DNAH8,DRC1,MAP2,MARK4,MTCL1,NAV1,NEURL1,NUMA1,PSRC1,SPAG1,SPAG17,TEKT2,TTLL5,TTLL6,UBE2B,ZMYND10,ZNF207	MammalFishAncestor	75.8435
GO.Biological.Process	GO:0002286	T.cell.activation.involved.in.immune.response	424	1.168533e-80	1.509394e-76	3.559892e-79	2.250193e+0	APBB1IP,ATP7A,BATF,EIF2AK4,F2RL1,FOXP1,GATA3,ICAM1,LEF1,RAB27A,RORA,STAT3,TSC1	MammalFishAncestor	75.8212
GO.Biological.Process	GO:0006974	cellular.response.to.DNA.damage.stimulus	425	1.214239e-80	1.568433e-76	3.690429e-79	1.319559e+0	AATF,ABRAXAS1,ACTL6A,AKT1,ALKBH2,ALKBH5,AP5Z1,AQR,ARID3A,ARMT1,ASCC3,ASTE1,ATF2,ATM,ATRX,BATF,BCCIP,BCL2L10,BOK,BRCA2,BRIP1,C14orf39,CCNH,CCNO,CDC7,CDK3,CDK5RAP3,CEP164,CHAF1B,CHRNA4,CLOCK,CLSPN,CNOT7,CNOT9,COPS2,COPS4,COPS5,COPS7A,CUL4A,CUL4B,DCLRE1A,DDIT3,DDX1,DNA2,DTL,EGLN3,EIF2AK4,ENDOV,EP300,EPC2,ERCC2,ERCC6,ETAA1,EYA1,FAAP100,FANCC,FANCI,FNIP2,FOXN3,FOXO3,FTO,HELQ,HERC2,HIST1H4A,HIST1H4B,HIST1H4C,HIST1H4D,HIST1H4E,HIST1H4F,HIST1H4H,HMGA1,HUWE1,IMMP2L,ING4,INO80,INO80D,INTS7,JMY,KIN,MAP3K20,MAPK12,MARF1,MBD4,MCL1,MCMDC2,MCTS1,MEIOB,MEN1,MGMT,MLH3,MNAT1,MOAP1,MRPS9,MSH6,MTOR,MUM1,MYO6,NABP2,NEK1,NEXMIF,NFATC2,NIPBL,NONO,NPLOC4,NTHL1,PDS5A,PDS5B,PHLDA3,PMS2,POLA1,POLE,POLG,POLK,POLL,POLR2A,POLR2E,POLR2K,PRKDC,PSMD14,RAD54B,RAD9B,RBBP6,RBL2,RBX1,RECQL5,REV3L,RFC1,RFC5,RGCC,RIF1,RNF111,RPA1,RPS27L,RRM2B,RTEL1,RTEL1-TNFRSF6B,SETD2,SFN,SFR1,SHISA5,SHPRH,SLC30A9,SLF1,SLF2,SMC1A,SMC3,SMUG1,STK11,SYF2,TAF1,TANK,TAOK1,TAOK3,TFAP4,TFDP1,TIPIN,TLK1,TP53BP1,TP73,TRIP12,TRRAP,UBA52,UBB,UBE2A,UBE2B,UBE2U,UBR5,UNG,UPF1,USP1,USP43,USP45,USP47,WAC,WDR48,XRCC3,ZBTB4,ZFYVE26,ZSWIM7	MammalFishAncestor	75.8045
GO.Biological.Process	GO:1900825	regulation.of.membrane.depolarization.during.cardiac.muscle.cell.action.potential	426	1.369198e-80	1.768593e-76	4.151627e-79	5.601787e+0	ANK3,GJA5,SLMAP	MammalFishAncestor	75.7524
GO.Biological.Process	GO:0006417	regulation.of.translation	427	1.753876e-80	2.265482e-76	5.305578e-79	1.424755e+0	AGO1,AGO3,AGO4,AKT1,BARHL2,C12orf65,CIRBP,CNOT7,CNOT9,CPEB2,CPEB3,CYFIP1,DDX1,DDX3X,DDX6,DGCR8,DHX9,DICER1,DNAJC3,EIF2AK1,EIF2AK4,EIF2B2,EIF2S1,EIF4B,EIF4E3,EIF4EBP2,EIF4EBP3,EIF4G1,EIF4G2,EIF4G3,EIF5A,EIF5A2,ENC1,ENSG00000203546,ESR1,FOXO3,FXR1,GAPDH,GCN1,GLE1,H3F3B,HIST1H3A,HIST1H3B,HIST1H3C,HIST1H3D,HIST1H3E,HIST1H3F,HIST1H3G,HIST1H4A,HIST1H4B,HIST1H4C,HIST1H4D,HIST1H4E,HIST1H4F,HIST1H4H,HNRNPD,IMPACT,LARP4,LARP4B,LARS,LRPPRC,LSM14A,LSM14B,MAP2K1,METTL14,MPV17L2,MTG2,MTOR,MYCN,NCOR1,NEURL1,NOLC1,NUP133,NUP188,NUP210,NUP214,NUP93,OGFOD1,PA2G4,PABPC1,PIWIL1,POLR2A,POLR2E,POLR2K,PRKRA,PSTK,PUM1,PUM2,RAN,RANBP2,RBM4B,RIDA,RMND1,RPL10,RPL5,RPS27L,RPS6KB1,SECISBP2L,SEH1L,SMAD1,SMAD3,STAT3,SYNCRIP,TARS2,TNRC6A,TOB1,TPR,TRAP1,TSC1,UCN,UNK,UPF1,UPF3B,UQCC2,YBX2,YTHDF1,ZC3H10,ZC3H12D,ZC3H7B,ZFP36L2,ZNF540	MammalFishAncestor	75.6448
GO.Biological.Process	GO:0022011	myelination.in.peripheral.nervous.system	428	2.438774e-80	3.150164e-76	7.360197e-79	2.730564e+0	ADAM22,AKT1,ARHGEF10,CNTNAP1,DAG1,DICER1,MPP5,MYOC,NF1,PARD3,POU3F1,POU3F2	MammalFishAncestor	75.5017
GO.Biological.Process	GO:0021766	hippocampus.development	429	4.703902e-80	6.076030e-76	1.416324e-78	1.801415e+0	ANXA3,BBS2,DCLK2,DLX1,DLX2,EMX2,EZH1,GLI3,GSK3B,HTR5A,KDM6B,KIF14,KIF5B,LEF1,MDK,MKKS,NKX2-1,NR2E1,NR4A3,OGDH,PAPD4,PHLPP2,PROX1,PTPRS,RELN,TSC1,UQCRQ,XRN2,ZEB2	MammalFishAncestor	75.2164
GO.Biological.Process	GO:0050796	regulation.of.insulin.secretion	430	5.699127e-80	7.361562e-76	1.711991e-78	1.519121e+0	ABCC8,ACVR1C,ADCY5,ADRA2A,BMP8A,CACNA1A,CACNA1C,CACNA1D,CFTR,CLOCK,CRH,DPP4,ENSA,ENY2,FKBP1B,FOXA2,G6PC2,GCG,GLP1R,GPR27,HADH,HMGCR,IRS2,ITPR1,ITPR2,ITPR3,KCNJ11,KIF5B,MIDN,MTNR1B,NKX6-1,NLGN2,NOV,NRXN1,PDE8B,PDX1,PFKM,PIM3,PPP3CB,PRKCA,RAP1A,RAPGEF4,RBP4,SLC25A4,SLC2A2,SNAP25,SREBF1,SRI,TARDBP,TCF7L2,UQCC2	MammalFishAncestor	75.133
GO.Biological.Process	GO:2000343	positive.regulation.of.chemokine.(C-X-C.motif).ligand.2.production	431	1.072154e-79	1.384901e-75	3.213228e-78	5.688612e+0	MBP,MCOLN2,POSTN	MammalFishAncestor	74.8586
GO.Biological.Process	GO:0048193	Golgi.vesicle.transport	432	1.450911e-79	1.874142e-75	4.338291e-78	1.464123e+0	ANK2,ANK3,ANKFY1,AP1G1,AP3B2,ARF4,ARFGAP1,ARFGEF2,ARFRP1,ARL1,ATP9A,ATP9B,BBS2,BCAP31,CAPZA1,CAPZA2,CCDC22,CHIC2,CNIH2,COL7A1,COPB1,COPB2,COPZ1,COPZ2,CORO7,CSNK1D,CUX2,CYTH3,DCTN2,DOPEY1,DOPEY2,DYNC1H1,DYNC1I1,DYNC1I2,ENSG00000256060,EXOC1,EXOC5,F9,FOLR1,GAS6,GBF1,GCC2,GOLGA3,GOLPH3L,GORASP1,HTT,KIF23,KIF3A,KIF3B,KIF3C,KIF5A,KLC1,KLC2,KLHL12,KRT18,LAMP1,LLGL1,MACF1,MON2,MYO18A,MYO5A,NAPG,NBAS,PACS1,PITPNB,PPP6C,RAB10,RAB1B,RABIF,SAR1A,SAR1B,SCAMP1,SCFD1,SEC16A,SEC22A,SEC22C,SEC23IP,SEC24A,SEC24C,SEC24D,SEC31A,SNAP23,SNX2,SORT1,SPTA1,SPTAN1,SPTBN1,SPTBN2,SPTBN4,STX17,TBC1D14,TRAPPC2,TRAPPC2L,VPS13A,VPS13C,VPS54,VTI1A,VTI1B,WHAMM,YIF1A	MammalFishAncestor	74.7272
GO.Biological.Process	GO:0045665	negative.regulation.of.neuron.differentiation	433	1.776392e-79	2.294566e-75	5.299228e-78	1.417267e+0	ADCY6,BAG5,CDKL3,CERS2,DDX6,DENND5A,DLX1,DLX2,DNM3,EDNRB,EIF2AK4,EPHA4,FKBP4,FOXO3,FSTL4,GFI1,GLI3,GORASP1,GSK3B,ID2,INPP5F,IRX3,ISL2,JAG1,KANK1,LRIG2,LRP1,MCF2,MED1,MEIS1,MIB1,MT3,NKX2-2,NLGN3,NOTCH1,NR2E1,NR2F1,NTN1,OMG,PAQR3,PAX6,PHOX2B,POU4F2,PTPRG,PTPRS,RAPGEF2,RHOA,RNF6,RTN4,RTN4RL1,SEMA3F,SEZ6,SHH,SIX3,SOX2,SPART,THOC2,TP73,TRPV4,TSC1,ZHX2,ZNF536	MammalFishAncestor	74.6393
GO.Biological.Process	GO:0072384	organelle.transport.along.microtubule	434	3.472759e-79	4.485763e-75	1.033586e-77	2.134831e+0	AP3B1,AP3B2,AP3M1,ARHGAP21,BLOC1S5,DYNC1H1,DYNC1I1,HTT,KIF1B,KIF23,KIF3A,KIF3B,KIF3C,KIF5B,LRPPRC,NDE1,NDEL1,PEX14,PRKCZ,RHOT1,RHOT2,UBB	MammalFishAncestor	74.3482
GO.Biological.Process	GO:0007041	lysosomal.transport	435	3.500527e-79	4.521631e-75	1.039455e-77	1.959617e+0	AKTIP,ANKFY1,AP1G1,AP3B1,AP3M1,ARSB,CDX2,GCC2,GNPTAB,LAMP1,LAMP2,LARS,LYST,NEDD4,PCDHGA3,PCSK9,RAB12,RHOB,RILP,SORT1,STX8,TMEM106B,VPS33A,VPS39,VPS41,VPS54	MammalFishAncestor	74.3447
GO.Biological.Process	GO:0046470	phosphatidylcholine.metabolic.process	436	4.218856e-79	5.449496e-75	1.249884e-77	2.212511e+0	ABHD3,CHPT1,ENPP2,LIPC,LPCAT1,LPCAT2,LPCAT3,LPIN2,MBOAT2,PCYT1B,PLA2G4A,PLA2G4B,PLA2G4F,PNPLA8,PON1,SLC44A4,STARD7	MammalFishAncestor	74.2636
GO.Biological.Process	GO:0090307	mitotic.spindle.assembly	437	4.455751e-79	5.755494e-75	1.317047e-77	2.604860e+0	ABRAXAS2,ARHGEF10,BCCIP,CLASP1,FLNA,KIF23,KIF3B,MZT1,NEK2,PIBF1,RAB11A,RHOA,SPICE1,TUBGCP4,TUBGCP5,TUBGCP6,WRAP73,ZNF207	MammalFishAncestor	74.2399
GO.Biological.Process	GO:1905600	regulation.of.receptor-mediated.endocytosis.involved.in.cholesterol.transport	438	5.550388e-79	7.169436e-75	1.636858e-77	7.628327e+0	ANXA2,LDLRAP1,PCSK9	MammalFishAncestor	74.1445
GO.Biological.Process	GO:0071322	cellular.response.to.carbohydrate.stimulus	439	1.325210e-78	1.711774e-74	3.899257e-77	1.888268e+0	ENDOG,FOXO3,GAS6,GCLC,GCLM,GJB6,ICAM1,IRS2,KCNJ11,MEN1,PAX2,PDK3,POLG,PRKCB,PTPRN,PTPRN2,RAB11FIP2,RAF1,RAP1A,SERPINF1,SIN3A,SLC26A6,SLC2A5,TWNK,UNC13B,ZNF236	MammalFishAncestor	73.7666
GO.Biological.Process	GO:0034373	intermediate-density.lipoprotein.particle.remodeling	440	1.422658e-78	1.837647e-74	4.176471e-77	9.354654e+0	LIPC	MammalFishAncestor	73.7357
GO.Biological.Process	GO:0042073	intraciliary.transport	441	1.528160e-78	1.973924e-74	4.476019e-77	2.546443e+0	CEP131,DYNC2H1,DYNC2LI1,ICK,IFT122,IFT43,IFT80,IFT81,IFT88,KIF17,KIF3A,KIF3B,KIF3C,RABL2B,SSX2IP,TNPO1,TTC21A,TTC21B,TTC30A,TTC30B,WDR19,WDR34	MammalFishAncestor	73.7047
GO.Biological.Process	GO:0016925	protein.sumoylation	442	1.531477e-78	1.978209e-74	4.475586e-77	2.107643e+0	EYA1,IFIH1,KIAA1586,L3MBTL2,MITF,NUP133,NUP188,NUP210,NUP214,NUP93,PIAS1,RANBP2,RANGAP1,SAE1,SEH1L,SENP1,SENP6,SP3,SUMO4,TOP1,TOP2B,TP53BP1,TPR,ZNF451	MammalFishAncestor	73.7037
GO.Biological.Process	GO:0021680	cerebellar.Purkinje.cell.layer.development	443	2.205553e-78	2.848913e-74	6.430954e-77	2.626117e+0	ATP7A,HERC1,KIF14,LDB1,LHX1,NAGLU,RERE,RORA,SEZ6,SPTBN2,UQCRQ	MammalFishAncestor	73.5453
GO.Biological.Process	GO:0045687	positive.regulation.of.glial.cell.differentiation	444	2.792611e-78	3.607216e-74	8.124360e-77	2.208892e+0	DAG1,DICER1,GSX2,MTOR,NKX2-2,NKX6-1,NKX6-2,NOTCH1,PPARG,SHH,TENM4,TP73	MammalFishAncestor	73.4428
GO.Biological.Process	GO:0060348	bone.development	445	2.865766e-78	3.701710e-74	8.318449e-77	1.487580e+0	ABI1,ALPL,ANKRD11,ANXA2,ASXL1,BMP6,CHSY1,COL1A1,COL2A1,COMP,DHRS3,DLX5,EP300,FAT4,FGF8,FOXN3,FOXP1,GLI3,HOXA11,HOXB4,INPPL1,INSIG1,KIT,LRRK1,MATN1,MED1,MEF2C,MEGF8,MEIS1,MYOC,NAB1,OSR2,PAX1,PITX2,PTPN6,RAB23,RARB,RHOA,RYR1,SFRP2,SHOX2,SLC38A10,SMAD1,SMAD9,SP5,SPARC,SPNS2,SULF1,SULF2,TFAP2A,TGFB3,TRPV4	MammalFishAncestor	73.4316
GO.Biological.Process	GO:0002263	cell.activation.involved.in.immune.response	446	3.831654e-78	4.949347e-74	1.109719e-76	1.362470e+0	ACAA1,ACLY,ADAM10,ALDOC,AMPD3,ANXA2,ANXA3,APBB1IP,APEH,APRT,ARHGAP45,ARHGAP9,ARSA,ARSB,ATG7,ATP11B,ATP6V0A1,ATP6V1D,ATP7A,AZU1,BATF,BIN2,BRI3,C5AR1,CD180,CD40LG,CDH17,CEP290,CFD,CHGA,CNN2,COPB1,CPNE1,CTSS,CYFIP1,DDOST,DDX3X,DIAPH1,DNAJC13,DNAJC3,DNAJC5,DYNC1H1,EIF2AK4,ELANE,ERP44,F2RL1,FOLR3,FOXP1,GALNS,GATA3,GBF1,GCA,GHDC,GPI,GPR84,HEXB,HPSE,HSP90AA1,HUWE1,HVCN1,ICAM1,IDH1,IMPDH2,IQGAP2,JUP,KCNAB2,KIT,LAMP1,LAMP2,LAMTOR1,LEF1,LPCAT1,LRP1,LTA4H,MAGT1,METTL7A,MSH6,NEU1,NR4A3,P2RX1,PA2G4,PGM1,PIK3CD,PKP1,PLAC8,PLCL2,PPIA,PRKCD,PRTN3,PSMA5,PSMB7,PSMD11,PSMD12,PSMD14,PSMD2,PSMD6,PTPN6,PTPRN2,PYGL,QSOX1,RAB10,RAB18,RAB27A,RAB3A,RAB5C,RAP1A,RHOA,RHOF,ROCK1,RORA,SBNO2,SCAMP1,SERPINA3,SLC2A5,SNAP23,SNAP25,SNAP29,SPTAN1,SRP14,STAT3,STXBP3,SWAP70,TMEM30A,TSC1,TUBB4B,TXNDC5,UBR4,UNC13D,VCL	MammalFishAncestor	73.3055
GO.Biological.Process	GO:0045664	regulation.of.neuron.differentiation	447	3.930151e-78	5.076576e-74	1.135699e-76	1.232511e+0	ADCY6,ADGRB3,AKT1,ALKAL1,AMIGO1,ARSB,ATF1,BAG5,BAIAP2,BARHL2,BEND6,BMP6,CAMSAP2,CASZ1,CDH4,CDK5RAP3,CDKL3,CDKL5,CERS2,CHN1,CPEB3,CPNE1,CPNE9,CRTC1,CSNK1D,CTTN,CUX2,CYB5D2,CYFIP1,DDX6,DENND5A,DLG5,DLX1,DLX2,DNM3,EDNRB,EIF2AK4,EIF4G1,ENC1,EPHA4,EYA1,FEZF1,FGF20,FIG4,FKBP1B,FKBP4,FN1,FOXO3,FSTL4,FYN,GATA3,GDF7,GFI1,GLI2,GLI3,GORASP1,GSK3B,HOXD3,ID2,IMPACT,INPP5F,IRX3,ISL2,JAG1,KALRN,KANK1,KCTD11,KDM4A,KIDINS220,KNDC1,LPAR3,LRIG2,LRP1,MACF1,MAP2,MAP2K1,MCF2,MED1,MEF2C,MEGF8,MEIS1,MIB1,MMD2,MT3,MTOR,MYCN,NCKIPSD,NCS1,NDEL1,NEDD4,NEURL1,NEUROD2,NEUROG3,NFE2L2,NKX2-2,NKX6-1,NLGN3,NOTCH1,NR2E1,NR2F1,NRCAM,NSMF,NTN1,OBSL1,OMG,PACSIN1,PAK1,PAQR3,PAX6,PHOX2B,PLXNB2,PLXNB3,PLXND1,POU3F2,POU4F2,PPP1R9A,PREX1,PROX1,PTK6,PTPRF,PTPRG,PTPRS,RAB11A,RAP1A,RAPGEF2,RARB,RELN,RETREG3,RHOA,RIMS2,RNF6,RTN4,RTN4RL1,SCARF1,SDK1,SEMA3F,SERPINF1,SEZ6,SFRP2,SHANK1,SHH,SHOX2,SHTN1,SIPA1L1,SIX1,SIX3,SNAP25,SNX3,SOX2,SPAG9,SPART,SS18L1,SSH1,SSH2,STK11,STK24,STK25,SYT1,SYT2,SYT3,TBR1,TCF12,TENM3,THOC2,TMEM106B,TMEM30A,TNIK,TP73,TRIM67,TRPV2,TRPV4,TSC1,VLDLR,WNT7A,ZEB1,ZEB2,ZHX2,ZNF536	MammalFishAncestor	73.2944
GO.Biological.Process	GO:0021782	glial.cell.development	448	4.721281e-78	6.098479e-74	1.361268e-76	1.799844e+0	ADAM22,AKT1,ARHGEF10,CNTNAP1,DAG1,DICER1,EIF2B2,ERCC2,HDAC10,HDAC11,LAMB2,LRP1,MED12,MPP5,MT3,MYOC,NF1,NKX2-2,NKX6-2,PARD3,POU3F1,POU3F2,PRDM8,ROR1,SHH,TENM4,WASF3	MammalFishAncestor	73.2148
GO.Biological.Process	GO:0019693	ribose.phosphate.metabolic.process	449	8.626120e-78	1.114236e-73	2.481594e-76	1.422106e+0	ACAT1,ACLY,ADCY5,ADCY6,ADCY7,ADCY9,ADK,ADM,ADSS,ADSSL1,AFG1L,AK4,AK5,AK9,ALDOC,AMPD2,AMPD3,APRT,ATIC,ATP1A2,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP5S,ATP6V0A1,ATP6V0A2,ATP6V1A,COX6C,COX7B,COX8C,CROT,DLD,DLG4,ENO1,ENO2,ENO4,ENSG00000266953,GALK1,GAPDH,GNAI3,GPHN,GPI,H6PD,HK1,HKDC1,HMGCR,IMPDH2,MAGI3,MBIP,MFN1,MYH3,MYH4,MYH8,NADK,NDUFA1,NDUFA12,NDUFA13,NDUFA5,NDUFAF7,NDUFB10,NDUFB5,NDUFS1,NDUFS6,NDUFS7,NDUFV2,NME4,NMNAT1,NPPA,NPPB,NT5C2,NT5E,NUDT3,OGDH,OLA1,PAICS,PAPSS1,PDE3B,PDE4A,PDE4C,PDE7A,PDE8B,PFKM,PGAM4,PGK1,PGM1,PPAT,PRPS2,PYGL,RAB23,RFK,RORA,RPE,RPEL1,RPIA,SLC25A13,SLC35B2,SLC35B3,STOML2,SULT6B1,TAZ,TKT,TPI1,UCKL1,UCN2,UMPS,UPP2,UQCRHL,UQCRQ	MammalFishAncestor	72.953
GO.Biological.Process	GO:0060083	smooth.muscle.contraction.involved.in.micturition	450	1.107186e-77	1.430152e-73	3.178116e-76	4.873569e+0	KCNMA1	MammalFishAncestor	72.8446
GO.Biological.Process	GO:0046329	negative.regulation.of.JNK.cascade	451	1.188466e-77	1.535142e-73	3.403861e-76	2.449297e+0	AKT1,F2RL1,GPS2,HIPK3,MARVELD3,MECOM,MEN1,NCOR1,PDCD4,SFRP2,TAOK3,TP73,ZMYND11	MammalFishAncestor	72.8139
GO.Biological.Process	GO:0098840	protein.transport.along.microtubule	452	1.233278e-77	1.593025e-73	3.524392e-76	2.483481e+0	CEP131,DYNC2H1,DYNC2LI1,ICK,IFT122,IFT43,IFT80,IFT81,IFT88,KIF17,KIF1A,KIF3A,KIF3B,KIF3C,RABL2B,SSX2IP,TNPO1,TTC21A,TTC21B,TTC30A,TTC30B,WDR19,WDR34	MammalFishAncestor	72.7978
GO.Biological.Process	GO:0051961	negative.regulation.of.nervous.system.development	453	1.236449e-77	1.597121e-73	3.525654e-76	1.351126e+0	ABCC8,ADCY6,BAG5,C16orf45,CDKL3,CERS2,DDX6,DENND5A,DICER1,DLX1,DLX2,DNM3,DRD3,EDNRB,EIF2AK4,EPHA4,FIG4,FKBP4,FOXO3,FSTL4,GFI1,GLI3,GORASP1,GSK3B,ID2,IFT122,INPP5F,IRX3,ISL2,JAG1,KANK1,KCTD11,KDM4A,LRIG2,LRP1,MCF2,MED1,MEIS1,MIB1,MT3,MYCN,NEUROD2,NF1,NKX2-2,NKX6-1,NKX6-2,NLGN3,NOTCH1,NR2E1,NR2F1,NTN1,OMG,PAQR3,PAX6,PHOX2B,PITX3,POU4F2,PRKACB,PTPRG,PTPRS,RAPGEF2,RFX4,RHOA,RNF6,RTN4,RTN4RL1,SEMA3F,SEZ6,SHH,SIX3,SLIT1,SOX2,SPART,STAT3,THOC2,TP73,TRIM11,TRPV4,TSC1,VAX1,WNT7A,ZHX2,ZNF536	MammalFishAncestor	72.7967
GO.Biological.Process	GO:1900180	regulation.of.protein.localization.to.nucleus	454	1.449549e-77	1.872382e-73	4.124190e-76	1.505281e+0	AKT1,BAG3,BAMBI,BMP6,CCDC22,CCT4,CDK5RAP3,CYLD,DACT3,DCLK1,DCLK2,EDAR,EFCAB7,EMD,F2R,FLNA,FYN,GAS6,GLI3,GLIS2,GSK3B,HYAL2,JUP,KANK1,KEAP1,LZTS2,MDFIC,MED1,MTOR,MXI1,NF1,NFKBIA,NFKBIE,NODAL,NOV,NUP93,PIK3R2,PKD1,PKD2,PPM1A,PPM1B,PRKCD,PTGS2,RAB23,RHOA,SFRP2,SHH,SIN3A,SMAD3,SPHK1,SRI,STK11,SULF2,TGFB3,TLR7,TMSB4X,TPR,UBR5,ZIC1	MammalFishAncestor	72.7276
GO.Biological.Process	GO:0009949	polarity.specification.of.anterior/posterior.axis	455	1.509424e-77	1.949723e-73	4.285105e-76	6.457390e+0	SHH	MammalFishAncestor	72.71
GO.Biological.Process	GO:0014858	positive.regulation.of.skeletal.muscle.cell.proliferation	455	1.509424e-77	1.949723e-73	4.285105e-76	6.457390e+0	SHH	MammalFishAncestor	72.71
GO.Biological.Process	GO:0060782	regulation.of.mesenchymal.cell.proliferation.involved.in.prostate.gland.development	455	1.509424e-77	1.949723e-73	4.285105e-76	6.457390e+0	SHH	MammalFishAncestor	72.71
GO.Biological.Process	GO:0060783	mesenchymal.smoothened.signaling.pathway.involved.in.prostate.gland.development	455	1.509424e-77	1.949723e-73	4.285105e-76	6.457390e+0	SHH	MammalFishAncestor	72.71
GO.Biological.Process	GO:0061189	positive.regulation.of.sclerotome.development	455	1.509424e-77	1.949723e-73	4.285105e-76	6.457390e+0	SHH	MammalFishAncestor	72.71
GO.Biological.Process	GO:1905327	tracheoesophageal.septum.formation	455	1.509424e-77	1.949723e-73	4.285105e-76	6.457390e+0	SHH	MammalFishAncestor	72.71
GO.Biological.Process	GO:2000062	negative.regulation.of.ureter.smooth.muscle.cell.differentiation	455	1.509424e-77	1.949723e-73	4.285105e-76	6.457390e+0	SHH	MammalFishAncestor	72.71
GO.Biological.Process	GO:2000063	positive.regulation.of.ureter.smooth.muscle.cell.differentiation	455	1.509424e-77	1.949723e-73	4.285105e-76	6.457390e+0	SHH	MammalFishAncestor	72.71
GO.Biological.Process	GO:2000357	negative.regulation.of.kidney.smooth.muscle.cell.differentiation	455	1.509424e-77	1.949723e-73	4.285105e-76	6.457390e+0	SHH	MammalFishAncestor	72.71
GO.Biological.Process	GO:2000358	positive.regulation.of.kidney.smooth.muscle.cell.differentiation	455	1.509424e-77	1.949723e-73	4.285105e-76	6.457390e+0	SHH	MammalFishAncestor	72.71
GO.Biological.Process	GO:0035019	somatic.stem.cell.population.maintenance	465	2.236076e-77	2.888339e-73	6.211483e-76	1.757225e+0	BCL9,BCL9L,CDX2,CUL4A,FOXD3,FOXP1,KIT,LDB1,NR2E1,POLR2A,POLR2E,POLR2K,PRDM14,PRDM16,RAF1,SALL1,SALL4,SIX2,SOX2,STAT3,WNT7A,ZFP36L2,ZHX2	MammalFishAncestor	72.5394
GO.Biological.Process	GO:0006164	purine.nucleotide.biosynthetic.process	466	2.267430e-77	2.928839e-73	6.285063e-76	1.838966e+0	ACAT1,ADCY5,ADCY6,ADCY7,ADCY9,ADK,ADM,ADSS,ADSSL1,AK5,AK9,AMPD2,AMPD3,APRT,ATIC,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP5S,ATP6V0A1,ATP6V0A2,IMPDH2,NME4,NPPA,NPPB,PAICS,PAPSS1,PPAT,PRPS2,SLC25A13,SLC35B2,SLC35B3,STOML2,UCN2	MammalFishAncestor	72.5333
GO.Biological.Process	GO:0014902	myotube.differentiation	467	6.506367e-77	8.404274e-73	1.799630e-75	1.992097e+0	ACTA1,ADAM12,ADGRB3,BCL9,DNER,GPX1,HOMER1,KLHL40,KLHL41,MEF2C,MYEF2,NFATC2,NOS1,P2RX2,PITX2,RYR1,SHH,SIX4,SORT1,STAC3,TANC1	MammalFishAncestor	72.0755
GO.Biological.Process	GO:0021937	cerebellar.Purkinje.cell-granule.cell.precursor.cell.signaling.involved.in.regulation.of.granule.cell.precursor.cell.proliferation	468	9.909359e-77	1.279992e-72	2.735025e-75	3.916324e+0	GLI1,GLI2,LHX1,SHH	MammalFishAncestor	71.8928
GO.Biological.Process	GO:0032989	cellular.component.morphogenesis	469	1.397780e-76	1.805512e-72	3.849707e-75	1.218289e+0	ABI1,ACTA1,ACTC1,ACTG1,AGFG1,AKIP1,AMIGO1,ANK2,ANK3,ARHGEF26,ARX,ASXL1,ATL1,ATP7A,AUTS2,B4GAT1,BAIAP2,BOC,C12orf57,CAPN3,CASQ1,CCDC136,CDH4,CDKL3,CELSR2,CHN1,CLIC4,CNP,CNTNAP1,COL4A3BP,CPNE1,CRYGB,CTTN,CYFIP1,DAG1,DCLK1,DICER1,DLG4,DLX5,DMRT1,DOCK7,DPYSL4,DRGX,DSCAML1,EFNA2,EIF2AK4,EP300,EPHA4,ERCC2,FEZF1,FGF8,FIG4,FLNA,FLNB,FN1,FOXB1,FOXD1,FRY,FRYL,FYN,GAB2,GATA3,GDF7,GLI2,GLI3,GNPAT,GP5,IMPACT,IRS2,ISL2,KIDINS220,KIF14,KIF5A,KIF5B,KIF5C,KLHL10,KLHL41,KRT8,LAMA2,LAMB1,LAMB2,LAMC1,LEF1,LGI1,LHX1,LHX3,LHX4,LHX9,LLGL1,LMOD2,MAP2,MATN1,MATN2,MED1,MEF2C,MET,MFF,MICALL2,MNX1,MPP5,MYBPC1,MYBPC2,MYBPC3,MYBPHL,MYH11,MYH3,MYL2,MYO7A,MYOM1,MYOM2,MYOZ1,MYOZ2,NDEL1,NDUFS6,NKX2-1,NKX2-8,NLGN3,NODAL,NOTCH1,NR2E1,NR4A2,NR4A3,NRCAM,NRP2,NRXN1,NTN1,NTN4,OBSCN,OBSL1,OMG,OTX2,PACSIN1,PAK1,PALLD,PARD3,PARVA,PAX2,PAX6,PDGFRA,PDZD7,PHOX2B,PIK3CB,PIK3CD,PIKFYVE,PLCG1,PLXNB3,POSTN,POU4F1,POU4F2,POU4F3,PPP3CB,PRDM14,PREX2,PRKCA,PRKCQ,PRKCZ,PROX1,PROX2,PTCH1,PTPN6,PTPRZ1,RAB10,RAB3A,RADIL,RAP1GAP,RELN,RERE,RILPL1,RILPL2,RNF165,ROCK1,SART3,SCFD1,SEMA3B,SEMA3F,SEMA5B,SH3GL2,SHANK1,SHH,SHROOM1,SHTN1,SIX4,SLC11A2,SLC1A3,SLC9A6,SLIT1,SLITRK3,SNX2,SOX6,SPTA1,SPTAN1,SPTBN1,SPTBN2,SPTBN4,SSH1,STK11,STK24,STK25,SUPV3L1,SZT2,TBCE,TCAP,TCTN1,TENM1,TENM2,TENM3,TENM4,TFCP2L1,THOC2,TMEM106B,TMF1,TOP2B,TPM1,TXNDC8,TYRO3,UBB,ULK1,UNK,USP33,USP9X,VAX1,VCL,VLDLR,VPS33A,WASF1,WASL,WDPCP,WDR19,WEE1,WNT7A,ZEB2	MammalFishAncestor	71.7434
GO.Biological.Process	GO:0030097	hemopoiesis	470	1.517224e-76	1.959798e-72	4.169783e-75	1.312914e+0	ABI1,ADAM17,ANXA2,ARIH2,ASXL1,ATM,ATP11C,ATP7A,BATF,BRCA2,C12orf29,CBFA2T3,CD4,CD40LG,CDH17,CEBPD,CSF2,CUL4A,CYLD,DCSTAMP,DLL4,DNAJA3,EFNA2,EIF2AK1,EP300,ERCC2,EVI2B,F2RL1,FARP2,FLT3,FNIP1,FOXP1,FZD8,GAB2,GAS6,GATA3,GFI1,GLI3,HERC6,HOXB3,HOXB4,HOXB7,HYAL2,IL3,INHA,INHBA,JAG1,KCNAB2,KDR,KIT,KITLG,KMT2A,LEF1,LEPR,LRRC8A,LRRK1,MECOM,MED1,MEF2C,MEIS1,MLF1,MMP21,MT1G,MYO1E,NFE2L1,NKAP,ONECUT1,OSTM1,PAPD4,PAX1,PDGFRA,PGM3,PIK3CD,PLCL2,PPARG,PPP3CB,PREX1,PRKDC,PRRC2C,PRTN3,PTPN2,PTPN6,PTPRZ1,PYGO1,RASGRP4,RBM47,RHOH,RORA,RRS1,RUNX3,SART3,SATB1,SBNO2,SFRP2,SH3PXD2A,SHH,SIN3A,SLC11A2,SOX6,SP3,SPTA1,STAT3,STAT5B,STK11,STK3,TAZ,TBX21,TCF7,TCTA,TET2,TGFBR3,TNFRSF11A,TNFSF11,TPO,TSC1,TUSC2,TWSG1,TYRO3,VPS33A,WDR7,WNT2B,ZBTB24,ZFP36L2	MammalFishAncestor	71.7078
GO.Biological.Process	GO:0033092	positive.regulation.of.immature.T.cell.proliferation.in.thymus	471	7.352572e-76	9.497317e-72	2.016416e-74	6.284938e+0	SHH	MammalFishAncestor	71.0224
GO.Biological.Process	GO:0030029	actin.filament-based.process	472	8.825027e-76	1.139929e-71	2.415103e-74	1.313302e+0	ABI1,ACTA1,ACTB,ACTC1,ACTG1,ADRA2A,ANK2,ARHGAP12,ARPC3,ARPC5L,ATP2C1,AUTS2,BAIAP2,BAIAP2L1,CACNA1C,CACNA1D,CACNA1G,CACNA2D1,CAMK2D,CAPN3,CASQ1,CGNL1,CNN2,COBLL1,CORO1C,CORO6,CORO7,CTTN,DES,DIAPH1,DNAJB6,ERMN,FARP2,FGD6,FHL3,FLII,FLNA,FLNB,FRY,FRYL,FSCN1,FSCN2,GJA5,INF2,INPPL1,IQGAP2,IQSEC1,IQSEC2,JMY,KCND3,KCNJ3,KCNJ8,KIF23,KIT,KLHL41,KRT8,LIMCH1,LLGL1,LMOD2,LURAP1,MAPKAP1,MICAL2,MICALL2,MSRB1,MYBPC1,MYBPC2,MYBPC3,MYBPHL,MYH10,MYH11,MYH2,MYH3,MYH4,MYH8,MYL2,MYL6B,MYO18A,MYO1E,MYO5A,MYO6,MYO7A,MYOM1,MYOM2,MYOZ1,MYOZ2,NEB,NF1,NISCH,OBSCN,OBSL1,PACSIN1,PAK1,PAK5,PAK6,PALLD,PARVA,PDGFRA,PDLIM4,PI4KA,PLEK2,PPP1R9A,PREX1,PRKCZ,PROX1,RHOA,RHOF,RND1,ROCK1,RYR2,S1PR2,SCN1A,SCN5A,SHROOM1,SHTN1,SIPA1L1,SIX4,SPIRE1,SPTA1,SSH1,SSH2,STRIP1,SWAP70,TBCK,TCAP,TMSB4X,TNIK,TNNC1,TNNI1,TNNT2,TPM1,TRPV4,USH1C,VIL1,WASF1,WASF3,WASHC1,WASL,WHAMM,WIPF1,XIRP2	MammalFishAncestor	70.9431
GO.Biological.Process	GO:0072594	establishment.of.protein.localization.to.organelle	473	1.061176e-75	1.370721e-71	2.897930e-74	1.439406e+0	AKT1,AP3B1,AP3M1,BMF,BRCA2,CSE1L,DAG1,DDIT3,DNAJC19,DNLZ,FAM53B,GCC2,GNPTAB,GPN3,GRPEL1,HEATR3,HK1,HSP90AA1,HSPA4,IFT122,IMMP1L,IMMP2L,IPO9,KPNA2,KPNA4,LAMP1,LAMP2,LARS,MFF,MFN2,MOAP1,MT3,MTX2,MTX3,NABP2,NCKIPSD,NDUFA13,NEDD4,NFKBIA,NUP133,NUP188,NUP214,PACS1,PAM16,PEX14,PEX2,PEX5,PEX5L,PHB2,PIK3R4,PMM1,PMPCA,RAB10,RAB11A,RAN,RANBP1,RANBP2,RERE,RPL10,RPL19,RPL21,RPL22,RPL27A,RPL30,RPL32,RPL35,RPL39,RPL4,RPL41,RPL5,RPL9,RPLP1,RPS10,RPS15,RPS2,RPS26,RPS3A,RYR2,SEC63,SIX2,SIX3,SNF8,SNUPN,SPTBN1,SRP14,SRP54,SRP68,SRP72,STAT3,TNPO1,TNPO3,TOB1,TOMM20,TPR,TSC2,TSPAN10,UBA52,VPS41,VTI1A,VTI1B,ZFYVE9	MammalFishAncestor	70.8631
GO.Biological.Process	GO:0043433	negative.regulation.of.sequence-specific.DNA.binding.transcription.factor.activity	474	1.414382e-75	1.826957e-71	3.854340e-74	1.623416e+0	ACOD1,BHLHE40,BRMS1,BTRC,CDK5RAP3,CMKLR1,COMMD6,CTNNBIP1,CYLD,DDIT3,EIF2AK4,ERBIN,ESR1,FLNA,FOXA2,FZD6,GAS6,GFI1,GLIS2,ID2,KEAP1,MAP2K5,MED13,MEN1,NFKBIA,OTULIN,PELI1,PEX14,PHB2,POU4F2,PROX1,PTCH1,RLIM,SETD6,TAF3,TAX1BP1,TCF7L2,TMSB4X	MammalFishAncestor	70.7383
GO.Biological.Process	GO:0072522	purine-containing.compound.biosynthetic.process	475	1.552013e-75	2.004735e-71	4.220495e-74	1.773947e+0	ACAT1,ADCY5,ADCY6,ADCY7,ADCY9,ADK,ADM,ADSS,ADSSL1,AK5,AK9,AMD1,AMPD2,AMPD3,APRT,ATIC,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP5S,ATP6V0A1,ATP6V0A2,IMPDH2,NME4,NPPA,NPPB,NT5E,PAICS,PAPSS1,PPAT,PRPS2,PRTFDC1,SLC25A13,SLC35B2,SLC35B3,STOML2,UCN2	MammalFishAncestor	70.6979
GO.Biological.Process	GO:0009116	nucleoside.metabolic.process	476	1.648604e-75	2.129502e-71	4.473743e-74	1.470231e+0	ACAT1,ACLY,ADK,ADSS,ADSSL1,AFG1L,AHCYL1,AK4,AK5,AK9,ALDOC,AMD1,AMPD3,APRT,ATIC,ATP1A2,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP5S,ATP6V0A1,ATP6V0A2,ATP6V1A,COX6C,COX7B,COX8C,CROT,DLD,DLG4,DPYS,ENO1,ENO2,ENO4,ENSG00000266953,GALK1,GAMT,GAPDH,GNAI3,GPHN,GPI,HK1,HKDC1,HMGCR,IMPDH2,MAGI3,MBIP,MFN1,MYH3,MYH4,MYH8,NADK,NDUFA1,NDUFA12,NDUFA13,NDUFA5,NDUFAF7,NDUFB10,NDUFB5,NDUFS1,NDUFS6,NDUFS7,NDUFV2,NME4,NMNAT1,NT5C2,NT5E,NUDT3,OGDH,OLA1,PAPSS1,PDC,PDCL2,PFKM,PGAM4,PGK1,PGM1,PPAT,PRPS2,PRTFDC1,RAB23,SLC25A13,SLC35B2,SLC35B3,STOML2,SULT6B1,TAZ,TPI1,UCKL1,UMPS,UPP2,UQCRHL,UQCRQ	MammalFishAncestor	70.6717
GO.Biological.Process	GO:0007020	microtubule.nucleation	477	2.058236e-75	2.658623e-71	5.573634e-74	3.351914e+0	AKAP9,CLASP1,CSNK1D,MZT1,NDE1,NDEL1,NIN,SLAIN2,TUBG1,TUBG2,TUBGCP4,TUBGCP5,TUBGCP6	MammalFishAncestor	70.5753
GO.Biological.Process	GO:1902749	regulation.of.cell.cycle.G2/M.phase.transition	478	2.127495e-75	2.748085e-71	5.749132e-74	1.632594e+0	AKAP9,ATM,CDC7,CDK3,CDK5RAP3,CEP131,CEP135,CEP152,CEP164,CEP192,CEP290,CEP76,CLASP1,CLSPN,CSNK1D,DCTN2,DTL,DYNC1H1,DYNC1I2,FANCI,FHL1,FOXN3,HAUS1,HSP90AA1,KIF14,MIIP,NDE1,NEK2,ODF2,OFD1,PHOX2B,PSMA1,PSMA5,PSMA6,PSMA7,PSMB2,PSMB7,PSMB8,PSMB9,PSMD11,PSMD12,PSMD14,PSMD2,PSMD6,RAB11A,RBX1,SDCCAG8,SIN3A,SKP1,SMARCD3,STOX1,SYF2,TAOK3,TUBA4A,TUBB4B,TUBG1,UBA52,UBB,USP47	MammalFishAncestor	70.561
GO.Biological.Process	GO:1904035	regulation.of.epithelial.cell.apoptotic.process	479	4.431179e-75	5.723754e-71	1.194938e-73	1.940112e+0	BOK,CD248,CD40LG,EIF2S1,FASLG,FGA,FGB,FGG,FOXO3,GAS6,GATA3,ICAM1,KDR,MTOR,NFE2L2,PDCD4,PDX1,RGCC,SORT1,TCF7L2	MammalFishAncestor	70.2423
GO.Biological.Process	GO:0030218	erythrocyte.differentiation	480	6.669094e-75	8.614469e-71	1.794681e-73	2.034666e+0	ERCC2,GATA3,INHA,INHBA,KIT,MED1,NFE2L1,PTPN2,SLC11A2,SOX6,SP3,TGFBR3	MammalFishAncestor	70.0648
GO.Biological.Process	GO:0032446	protein.modification.by.small.protein.conjugation	481	1.308542e-74	1.690244e-70	3.514020e-73	1.278296e+0	AKT1,AKTIP,AMFR,ANAPC10,ANAPC15,ANAPC7,AREL1,ARIH2,ARRDC1,ARRDC4,ASB14,ASB15,ASB16,ASB2,ASB3,ASB4,ASB7,ASB8,ATG7,BACH2,BIRC6,BIRC7,BTBD1,BTRC,BUB1B,BUB3,C18orf25,CAND2,CCDC22,CDCA3,CDK5RAP3,CHFR,CTR9,CUL2,CUL4A,CUL4B,CUL9,DCAF13,DCAF17,DCUN1D1,DCUN1D2,DERL1,DTL,ENC1,EYA1,FBXL14,FBXL18,FBXL20,FBXL22,FBXL3,FBXL4,FBXL5,FBXO11,FBXO21,FBXO30,FBXO43,FBXO9,FBXW4,G2E3,HECTD1,HECTD4,HERC1,HERC2,HERC3,HERC5,HERC6,HIST1H2BB,HIST1H2BC,HIST1H2BD,HIST1H2BE,HIST1H2BF,HIST1H2BG,HIST1H2BH,HIST1H2BI,HUWE1,IFIH1,JADE2,KBTBD11,KCTD10,KCTD11,KDM2B,KEAP1,KIAA1586,KLHDC8B,KLHL10,KLHL11,KLHL12,KLHL2,KLHL23,KLHL26,KLHL29,KLHL31,KLHL40,KLHL41,KLHL5,L3MBTL2,LMO7,LNX1,MARCH5,MARCH7,MED1,MED12,MIB1,MIB2,MITF,MKRN2,MSL2,MYCBP2,NEDD4,NEURL1,NEUROD2,NFE2L2,NUP133,NUP188,NUP210,NUP214,NUP93,OTULIN,PAX6,PCGF6,PDZRN3,PELI1,PEX2,PEX5,PIAS1,PRKDC,PSMA1,PSMA5,PSMA6,PSMA7,PSMB2,PSMB7,PSMB8,PSMB9,PSMD11,PSMD12,PSMD14,PSMD2,PSMD6,RANBP2,RANGAP1,RBBP6,RBX1,RLIM,RNF111,RNF133,RNF141,RNF152,RNF165,RNF19A,RNF213,RNF216,RNF34,RNF41,RNF6,RNFT1,RYBP,SAE1,SASH1,SEH1L,SELENOS,SENP1,SENP6,SH3RF1,SH3RF2,SHPRH,SKP1,SP3,SPSB2,SUMO4,SUZ12,TAF1,TOP1,TOP2B,TP53BP1,TPR,TRIM11,TRIM59,TRIM9,TRIP12,TRPC4AP,UBA5,UBA52,UBAC1,UBB,UBE2A,UBE2B,UBE2G1,UBE2K,UBE2O,UBE2U,UBE2Z,UBE3B,UBE3C,UBE4A,UBE4B,UBR3,UBR4,UBR5,UBR7,UCHL3,UFM1,USP5,USP9X,VCPIP1,WAC,WDSUB1,WSB2,ZER1,ZNF451	MammalFishAncestor	69.7721
GO.Biological.Process	GO:0046649	lymphocyte.activation	482	1.895742e-74	2.448730e-70	5.080353e-73	1.390845e+0	ADAM17,APBB1IP,ATM,ATP11C,ATP7A,BATF,CD180,CD4,CD40LG,CDH17,CHRNA4,CXCR5,CYLD,DDOST,DLL4,DNAJA3,DOCK8,DPP4,EIF2AK4,EP300,F2RL1,FKBP1B,FLT3,FNIP1,FOXP1,FYN,FZD8,GATA3,GLI3,ICAM1,IMPDH2,KIT,LEF1,LEPR,LRRC8A,MEF2C,MSH6,NEDD4,NKAP,ONECUT1,PAX1,PIK3CD,PLCL2,PPP3CB,PREX1,PRF1,PRKCB,PRKCD,PRKDC,PTPN2,RAB27A,RHOH,RORA,SATB1,SHH,SMAD3,SP3,STAT3,STAT5B,STK11,STOML2,SWAP70,TBX21,TCF7,TSC1,TUSC2,TYRO3,UNC13D,WASHC1,ZFP36L2	MammalFishAncestor	69.6111
GO.Biological.Process	GO:0033262	regulation.of.nuclear.cell.cycle.DNA.replication	483	2.293693e-74	2.962763e-70	6.134085e-73	3.176587e+0	ATRX,CDC7,CDT1,DACH1,INO80,TIPIN	MammalFishAncestor	69.5283
GO.Biological.Process	GO:2000736	regulation.of.stem.cell.differentiation	484	2.340459e-74	3.023171e-70	6.246221e-73	1.698678e+0	CDK12,ESRRB,GATA3,GATA6,H1FOO,H3F3B,HIST1H3A,HIST1H3B,HIST1H3C,HIST1H3D,HIST1H3E,HIST1H3F,HIST1H3G,HIST1H4A,HIST1H4B,HIST1H4C,HIST1H4D,HIST1H4E,HIST1H4F,HIST1H4H,HOXB4,JAG1,KMT2A,LDB1,LMO1,N4BP2L2,NFE2L2,NOTCH1,PDGFRA,PSMA1,PSMA5,PSMA6,PSMA7,PSMB2,PSMB7,PSMB8,PSMB9,PSMD11,PSMD12,PSMD14,PSMD2,PSMD6,SOX6,STAT3,TCF12,TP73,UBA52,UBB,ZFP36L2	MammalFishAncestor	69.5195
GO.Biological.Process	GO:0043473	pigmentation	485	4.966717e-74	6.415508e-70	1.322785e-72	1.710878e+0	AP1G1,AP3B1,ATP7A,BBS2,BBS5,BLOC1S5,DCT,DCTN2,EDAR,EDNRB,FIG4,GLI3,HPS6,KIT,KRT76,LEF1,LRMDA,LYST,MEF2C,MITF,MKKS,MYO5A,MYO7A,NF1,OCA2,POMC,RAB11A,RAB27A,RAB32,SPARC,SZT2,USP13,VPS33A,ZEB2	MammalFishAncestor	69.1928
GO.Biological.Process	GO:0006753	nucleoside.phosphate.metabolic.process	486	5.876367e-74	7.590503e-70	1.561832e-72	1.356256e+0	ACAT1,ACLY,ADCY5,ADCY6,ADCY7,ADCY9,ADK,ADM,ADSS,ADSSL1,AFG1L,AK4,AK5,AK8,AK9,ALDOC,AMPD2,AMPD3,APRT,ASPDH,ATIC,ATP1A2,ATP5A1,ATP5B,ATP5C1,ATP5D,ATP5EP2,ATP5G1,ATP5G3,ATP5L,ATP5S,ATP6V0A1,ATP6V0A2,ATP6V1A,CNP,COX6C,COX7B,COX8C,CROT,DCTD,DLD,DLG4,DNPH1,DTYMK,DUT,ENO1,ENO2,ENO4,ENSG00000266953,ENTPD8,FMO1,FMO2,GALK1,GAPDH,GNAI3,GPD2,GPHN,GPI,GPX1,H6PD,HK1,HKDC1,HMGCR,IDH1,IMPDH2,KCNAB2,LDHB,LHPP,MAGI3,MBD4,MBIP,MDH1,MFN1,MYH3,MYH4,MYH8,NADK,NAXD,NDUFA1,NDUFA12,NDUFA13,NDUFA5,NDUFAF7,NDUFB10,NDUFB5,NDUFS1,NDUFS6,NDUFS7,NDUFV2,NME4,NMNAT1,NMNAT2,NOX1,NPPA,NPPB,NT5C2,NT5C3B,NT5E,NTHL1,NUDT3,OGDH,OLA1,PAICS,PAPSS1,PDE3B,PDE4A,PDE4C,PDE7A,PDE8B,PFKM,PGAM4,PGK1,PGM1,PPAT,PRPS2,PTGS2,RAB23,RFK,RORA,RPE,RPEL1,RPIA,RRM2B,SLC22A13,SLC25A13,SLC35B2,SLC35B3,SLC5A8,SMUG1,STOML2,SULT6B1,TAZ,TKT,TPI1,UCKL1,UCN2,UMPS,UNG,UPP2,UQCRHL,UQCRQ	MammalFishAncestor	69.1197
GO.Biological.Process	GO:1902748	positive.regulation.of.lens.fiber.cell.differentiation	487	7.981300e-74	1.030945e-69	2.116929e-72	5.920905e+0	ZEB2	MammalFishAncestor	68.9868
GO.Biological.Process	GO:0010575	positive.regulation.of.vascular.endothelial.growth.factor.production	488	8.315672e-74	1.074135e-69	2.201097e-72	2.415613e+0	ADORA2B,ARNT,C5AR1,HPSE,NODAL,NOX1,PTGS2,RORA,SULF1,SULF2	MammalFishAncestor	68.9689
GO.Biological.Process	GO:0006651	diacylglycerol.biosynthetic.process	489	9.334484e-74	1.205735e-69	2.465716e-72	7.606570e+0	MOGAT1,PLCE1	MammalFishAncestor	68.9187
GO.Biological.Process	GO:2000195	negative.regulation.of.female.gonad.development	490	1.165217e-73	1.505111e-69	3.071655e-72	4.185415e+0	HYAL3,NR5A1,WT1,ZFPM2	MammalFishAncestor	68.8224
GO.Biological.Process	GO:0032368	regulation.of.lipid.transport	491	1.283662e-73	1.658106e-69	3.376998e-72	1.800177e+0	ABCA1,ABCA7,ABCB4,ABCG5,ABCG8,AGTR1,AKT1,ANXA2,ARV1,BMP6,CRH,CYP19A1,GALR1,GDF9,IRS2,KDM5B,LAMTOR1,LDLRAP1,LRP1,NCOR1,NFKBIA,PCSK9,PLA2R1,POMC,PON1,PPARG,PRKCD,PTCH1,SHH,TMF1,TNFRSF11A,TNFSF11,WASHC1	MammalFishAncestor	68.7804
GO.Biological.Process	GO:0019075	virus.maturation	492	1.469208e-73	1.897776e-69	3.857268e-72	7.177181e+0	MVB12B	MammalFishAncestor	68.7218
GO.Biological.Process	GO:0010874	regulation.of.cholesterol.efflux	493	2.062842e-73	2.664573e-69	5.404813e-72	3.166363e+0	ABCA1,ABCA7,LAMTOR1,LRP1,NFKBIA,PON1,PTCH1,SHH	MammalFishAncestor	68.5744
GO.Biological.Process	GO:0072009	nephron.epithelium.development	494	2.310740e-73	2.984783e-69	6.042071e-72	1.542151e+0	ACAT1,ADAMTS16,CTNNBIP1,EYA1,FAT4,FGF8,FOXD1,GATA3,GLI3,HNF1B,HOXA11,HOXD11,IRX1,IRX2,IRX3,JAG1,LAMB2,LHX1,MEF2C,MYO1E,NOTCH1,NPNT,NUP93,PAX2,PGF,PKD1,PKD2,POU3F3,PTCH1,SALL1,SHH,SIX1,SIX2,WT1	MammalFishAncestor	68.5251
GO.Biological.Process	GO:0021915	neural.tube.development	495	2.599969e-73	3.358380e-69	6.784606e-72	1.517901e+0	ADM,ALDH1A2,AMBRA1,ARID1A,CC2D2A,CTHRC1,DVL2,FGF8,FKBP8,FOLR1,FOXB1,FZD6,GDF7,GLI2,GLI3,GLMN,GSC,IFT122,ITPK1,KAT2A,KDM2B,LIAS,LMO4,LRP2,MED12,MIB1,NF1,NODAL,NOTCH1,NUP133,PAX2,PAX6,PKD1,PKD2,PLXNB2,PRKACB,PROX1,PTCH1,RPGRIP1L,SALL4,SETD2,SFRP2,SHH,STK3,TCF7,TCTN1,TSC1,TSC2,WDR19,ZEB2	MammalFishAncestor	68.4739
GO.Biological.Process	GO:0007228	positive.regulation.of.hh.target.transcription.factor.activity	496	3.162678e-73	4.085231e-69	8.236353e-72	6.023304e+0	SHH	MammalFishAncestor	68.3888
GO.Biological.Process	GO:0009408	response.to.heat	497	4.209750e-73	5.437734e-69	1.094111e-71	1.824102e+0	AKT1,ATXN3L,BAG3,CALCA,CASQ1,CLPB,DNAJA2,DNAJA3,DNAJB4,EIF2B2,EIF2S1,GCLC,HSP90AA1,MKI67,NF1,NOS1,PIRT,PSIP1,PTGS2,RPS6KB1,TFEC,TPR,TRPV2,TRPV4	MammalFishAncestor	68.2646
GO.Biological.Process	GO:0045321	leukocyte.activation	498	4.722488e-73	6.100038e-69	1.224907e-71	1.265372e+0	ACAA1,ACLY,ADAM10,ADAM17,ALDOC,AMPD3,ANXA2,ANXA3,APBB1IP,APEH,APRT,ARHGAP45,ARHGAP9,ARSA,ARSB,ATG7,ATM,ATP11B,ATP11C,ATP6V0A1,ATP6V1D,ATP7A,AZU1,BATF,BIN2,BRI3,C5AR1,CD180,CD4,CD40LG,CDH17,CEP290,CFD,CHGA,CHRNA4,CNN2,COPB1,CPNE1,CSF2,CTSS,CXCR5,CYFIP1,CYLD,DCSTAMP,DDOST,DDX3X,DIAPH1,DLL4,DNAJA3,DNAJC13,DNAJC3,DNAJC5,DOCK8,DPP4,DYNC1H1,EIF2AK4,ELANE,EP300,ERP44,F2RL1,FKBP1B,FLT3,FNIP1,FOLR3,FOXP1,FYN,FZD8,GALNS,GATA3,GCA,GHDC,GLI3,GPI,GPR84,HEXB,HPSE,HSP90AA1,HUWE1,HVCN1,HYAL2,ICAM1,IDH1,IMPDH2,IQGAP2,JUP,KCNAB2,KIT,LAMP1,LAMP2,LAMTOR1,LEF1,LEPR,LPCAT1,LRRC8A,LTA4H,MAGT1,MEF2C,METTL7A,MSH6,MT1G,NEDD4,NEU1,NKAP,NR4A3,ONECUT1,P2RX1,PA2G4,PAX1,PGM1,PIK3CD,PKP1,PLAC8,PLCL2,PPIA,PPP3CB,PREX1,PRF1,PRKCB,PRKCD,PRKDC,PRTN3,PSMA5,PSMB7,PSMD11,PSMD12,PSMD14,PSMD2,PSMD6,PTPN2,PTPN6,PTPRN2,PYGL,QSOX1,RAB10,RAB18,RAB27A,RAB3A,RAB5C,RAP1A,RHOA,RHOF,RHOH,ROCK1,RORA,SATB1,SBNO2,SCAMP1,SELPLG,SERPINA3,SHH,SLC2A5,SLC7A2,SMAD3,SNAP23,SNAP25,SNAP29,SP3,SPTAN1,SRP14,STAT3,STAT5B,STK11,STOML2,STXBP3,SWAP70,TBX21,TCF7,TLR7,TLR8,TMEM30A,TSC1,TUBB4B,TUSC2,TXNDC5,TYRO3,UBR4,UNC13D,VCL,WASHC1,ZFP36L2	MammalFishAncestor	68.2147
GO.Biological.Process	GO:0050708	regulation.of.protein.secretion	499	1.002177e-72	1.294512e-68	2.594212e-71	1.341288e+0	ABCC8,ACVR1C,ADCY5,ADRA2A,ARG2,BMP6,BMP8A,C5AR2,CACNA1A,CACNA1C,CACNA1D,CD40LG,CFTR,CLOCK,CRH,DHX36,DHX9,DPP4,DRD3,ENSA,ENY2,EXOC1,F2R,F2RL1,FFAR4,FGA,FGB,FGG,FKBP1B,FN1,FOXA2,FOXP1,G6PC2,GAPDH,GAS6,GATA3,GBP1,GCG,GJA5,GLMN,GLP1R,GOLPH3L,GPI,GPR27,HADH,HCAR2,HK1,HMGCR,HYAL2,IFIH1,IRS2,ITPR1,ITPR2,ITPR3,KCNJ11,KIF5B,LLGL1,LLGL2,MAPK11,MAPKBP1,MBP,MIDN,MTNR1B,MYO18A,MYOM1,NKX6-1,NLGN2,NOD2,NOV,NRXN1,PDE8B,PDX1,PFKM,PIM3,POSTN,PPIA,PPID,PPP3CB,PRKCA,PRKCZ,PTPN23,RAB11FIP3,RAP1A,RAPGEF4,RBP4,RGCC,RHBDF2,SEC24A,SLC25A4,SLC2A2,SNAP25,SPTBN1,SREBF1,SRGN,SRI,STXBP5,TARDBP,TCF7L2,TGFB3,TLR8,TMSB4X,TRPV4,UNC13B,UQCC2	MammalFishAncestor	67.8879
GO.Biological.Process	GO:0008202	steroid.metabolic.process	500	2.013861e-72	2.601304e-68	5.202609e-71	1.562630e+0	ABCA1,ABCB11,ACAA1,ACLY,ADM,ANGPTL3,APOB,ARV1,ATP8B1,CEL,CES1,CFTR,CLN8,CRH,CUBN,CYP17A1,CYP19A1,CYP2R1,CYP51A1,CYP7B1,DHCR24,DHRS9,ERG28,FDX2,GGPS1,HDLBP,HMGCR,HSD17B1,IDI1,IDI2,INSIG1,LDLR,LDLRAP1,LEPR,LIPC,LRP2,MSMO1,MT3,MVK,NR1I2,NR5A2,OSBPL1A,OSBPL6,OSBPL7,PCSK9,PON1,SCAP,SCARF1,SREBF1,STARD3,STAT5B,TFCP2L1,VLDLR	MammalFishAncestor	67.5848
#.GO.Biological.Process	12917	1	1000	MammalFishAncestor	inf