GO.Biological.Process	GO:0001817	regulation.of.cytokine.production	1	1e-300	1e-300	1e-300	1.337792e+0	ABCC8,ABL1,ACE2,ACP5,ADAM8,ADCYAP1,ADIPOQ,ADORA2B,ADRA2A,AFAP1L2,AGER,AGPAT1,AGPAT2,AGT,AGTR2,AKAP8,AKIRIN2,ALOX15B,ANGPT1,ANKRD17,ANKRD2,ANXA1,ANXA4,APOA1,APOA2,APOD,ARFGEF2,ARG1,ARG2,ARHGEF2,ARRB1,ARRB2,ASB1,ATF4,ATG5,ATP6AP2,AXL,BANK1,BAP1,BCL10,BCL3,BCL6,BIRC2,BIRC3,BPI,BRCA1,BST2,BTK,C1QBP,C1QTNF3,C3,C3AR1,C5,C5orf30,CACTIN,CADM1,CARD11,CARD16,CARD17,CARD18,CASP1,CASP5,CCBE1,CCDC88B,CCL19,CCL2,CCL3,CCM2L,CCR2,CCR7,CD14,CD2,CD226,CD24,CD274,CD276,CD28,CD2AP,CD34,CD36,CD3E,CD40,CD46,CD58,CD6,CD74,CD80,CD83,CD86,CD96,CDH3,CEBPB,CEBPG,CHIA,CHID1,CHUK,CIDEA,CLC,CLEC4E,CLEC6A,CLEC9A,CLU,CMKLR1,CRCP,CREB1,CRTAM,CRYBA1,CSF1R,CSK,CTNNB1,CX3CL1,CYBA,CYBB,CYP1B1,DDT,DDX3X,DDX41,DDX58,DDX60,DHX9,DLL1,DRD2,DTX4,EBI3,EGR1,EIF2AK2,EIF2AK3,ELF1,ENSG00000173366,EP300,EPHA2,EPX,EREG,ERRFI1,EZR,F11R,F2,F2R,F2RL1,FADD,FAM49B,FCER1G,FCN1,FERMT1,FFAR2,FFAR3,FFAR4,FGFR1,FGR,FLOT1,FLT4,FN1,FOXJ1,FOXP3,FURIN,FZD5,GAPDH,GAS6,GATA3,GATA4,GATA6,GBA,GDF2,GHSR,GPAM,GPATCH3,GPNMB,GPR18,GPRC5B,GPSM3,GSDMD,GSTP1,HAVCR2,HDAC2,HDAC7,HEG1,HGF,HHLA2,HIF1A,HMGB1,HMGB2,HMHB1,HMOX1,HPSE,HRAS,HSF1,HSP90AB1,HSPB1,HTR2B,IDO1,IFNA2,IFNAR1,IFNB1,IFNG,IFNL1,IGF2BP1,IGF2BP2,IGF2BP3,IKBKE,IL10,IL12A,IL12B,IL12RB1,IL12RB2,IL13,IL15,IL17A,IL17B,IL17F,IL17RA,IL17RB,IL17RC,IL18,IL18R1,IL1A,IL1B,IL1R2,IL1RAP,IL1RL1,IL1RL2,IL2,IL20RB,IL21,IL23A,IL23R,IL26,IL27,IL27RA,IL33,IL36A,IL36B,IL36RN,IL4,IL5RA,IL6,IL6R,IL6ST,IL9,INAVA,INHA,INHBA,INHBB,INPP5D,INS,IQGAP1,IRAK1,IRAK3,IRF1,IRF3,IRF4,IRF7,IRF8,ISG15,ISL1,ITCH,JAK2,JAK3,JPH4,KARS,KAT5,KLF2,KLF4,KLRK1,LAPTM4B,LBP,LEF1,LEP,LGALS9,LGR4,LILRA4,LILRB2,LITAF,LPL,LRRC32,LRRFIP1,LTB,LUM,LURAP1,LY96,LYN,MALT1,MAP2K3,MAP3K7,MAPK11,MAPK13,MAPK14,MAPK3,MAPKAPK2,MAST2,MB21D1,MC1R,MCOLN2,MEFV,MERTK,MIF,MMP12,MRE11,MUL1,MYB,NAV3,NCKAP1L,NDFIP1,NFAM1,NFATC4,NFKB1,NFKB2,NLRC3,NLRC5,NLRP1,NLRP10,NLRP2,NLRP7,NLRP9,NLRX1,NMI,NOD1,NOP53,NOS2,NR1H4,NR4A3,NUTF2,ORM1,ORM2,OTUD5,OTUD7B,P2RX7,PAEP,PANX1,PARK7,PCBP2,PDCD1LG2,PDE4B,PDE4D,PELI1,PER1,PF4,PGLYRP1,PGLYRP2,PGLYRP3,PIK3R1,PIN1,PLCB1,PLCG2,PML,POLR1C,POLR2F,POLR2H,POLR2L,POLR3A,POLR3B,POLR3C,POLR3D,POLR3E,POLR3F,POLR3GL,POLR3K,POMC,PQBP1,PRG2,PRG3,PRKCQ,PRKCZ,PRKD2,PRKDC,PTAFR,PTGER4,PTPN22,PTPRS,PYCARD,PYDC1,PYDC2,RAB7B,RAC1,RARA,RASGRP1,REL,RELA,RELB,RGCC,RIOK3,RIPK1,RIPK2,RIPK3,RNF125,RNF128,RNF135,RNF216,RNF26,RPS27A,RPS3,RPS6KA4,RPS6KA5,RSAD2,RUNX1,S1PR3,SAA1,SARS,SASH3,SCAMP5,SCGB1A1,SEC14L1,SELENOK,SEMA7A,SERPINB7,SETD2,SIGIRR,SLAMF6,SLC11A1,SMAD4,SMAD7,SNAI2,SOCS1,SOCS5,SOD1,SPHK1,SPN,SPON2,SRC,SSC5D,STAT1,STAT6,SULF2,SYK,SYT11,TAX1BP1,TBC1D23,TBK1,TGFB1,TGFB2,THBS1,TIA1,TICAM1,TIGIT,TIRAP,TKFC,TLR1,TLR10,TLR2,TLR3,TLR4,TLR5,TLR6,TLR9,TMEM173,TMIGD2,TNF,TNFAIP3,TNFRSF13C,TNFRSF14,TNFRSF21,TNFRSF8,TNFRSF9,TRAF2,TRAF3,TRAF3IP1,TRAF6,TRAIP,TRIB2,TRIL,TRIM21,TRIM25,TRIM32,TRIM6,TRPM4,TSPAN6,TSPO,TWIST1,TXK,UBA7,UBASH3A,UBC,UBE2J1,UBE2L6,UCN,UFD1,VSIG4,VTCN1,WNT11,WNT3A,WNT5A,XBP1,XCL1,XRCC5,XRCC6,YY1,ZBP1,ZBTB20,ZC3H12A,ZFP36,ZFPM1,ZNF580,ZP3	TetrapodAncestor	300
GO.Biological.Process	GO:0001933	negative.regulation.of.protein.phosphorylation	1	1e-300	1e-300	1e-300	1.356336e+0	ABL1,ADAR,ADARB1,ADIPOQ,ADORA2A,AIDA,AKT1S1,AMBP,ANGPT1,APC,APOE,ARRB1,ARRB2,ASH1L,ASPN,ATF3,ATG14,BAK1,BAX,BDKRB1,BDKRB2,BGN,BMP4,BMP7,C14orf166,C1QL4,C3orf33,C9orf72,CACTIN,CALM1,CALM2,CALM3,CAMK2N1,CAMK2N2,CASP3,CAV1,CAV3,CBL,CBLB,CBLC,CCNB1,CD109,CD300A,CDK5RAP1,CDKN1A,CDKN1B,CDKN1C,CDKN2A,CDKN2B,CDKN2C,CDKN2D,CEBPA,CEP85,CHAD,CHMP6,CHORDC1,CHP1,CIB1,CISH,CNKSR3,CRYBA1,CSK,CTDSP1,CTDSP2,CTDSPL,DAB2IP,DACT1,DBNDD2,DCN,DDIT4,DEPTOR,DGKQ,DKK1,DLG1,DMD,DMTN,DNAJA1,DNAJC10,DTNBP1,DUS2,DUSP1,DUSP10,DUSP16,DUSP18,DUSP19,DUSP2,DUSP21,DUSP22,DUSP26,DUSP3,DUSP6,DUSP7,DUSP8,DUSP9,DVL1,EFNA1,EIF3A,ENG,ENPP1,EPHA1,EPHB2,ERRFI1,EZR,F2RL1,FABP4,FAM129A,FAM212A,FAM212B,FBLN1,FBXO7,FGFR1OP,FKBP1A,FKTN,FLCN,FLRT1,FLRT2,FLRT3,FOXM1,FOXO1,GADD45A,GADD45B,GBA,GFRA2,GGNBP2,GMFB,GMFG,GNAQ,GP1BA,GPD1L,GPER1,GPRC5A,GPS1,GREM1,GSKIP,GSTP1,H2AFY,HDAC3,HEXIM1,HEXIM2,HGF,HHEX,HMGCR,HSPB1,HSPH1,IBTK,IGBP1,IGF1R,IL1B,IL2,IL6,INCA1,INPP5J,INPP5K,INSM1,IRAK3,ITCH,JUN,KAT2B,KIRREL1,KIRREL2,KLF4,LATS1,LATS2,LAX1,LDLRAD4,LEMD2,LIF,LMO3,LRP5,LRP6,LRRC15,LRRC19,LRRC3,LRRC3C,LRRC4,LRRC4C,LRRC66,LRRK2,LRRTM1,LRRTM3,LRRTM4,LRTM1,LRTM2,LYN,MAPK8IP1,MARVELD3,MAS1,MBIP,MECOM,MEN1,MICAL1,MLLT1,MLXIPL,MTOR,MVP,MYADM,MYC,MYOCD,NCK1,NCK2,NF1,NF2,NLRP6,NOG,NPM1,NTF3,NTRK3,NUP62,P2RX7,PAFAH1B1,PAK2,PARD3,PARD6A,PARK7,PARP14,PBK,PBLD,PDE4D,PDPK1,PER1,PHB,PID1,PIK3R2,PIN1,PINK1,PKIA,PKIB,PKIG,PKN1,PLK1,PLPP3,PMEPA1,PODN,PODNL1,PPARGC1A,PPEF2,PPM1E,PPM1F,PPP1R15A,PPP1R15B,PPP1R1A,PPP1R1C,PPP5C,PREX1,PRKAG2,PRKAR1A,PRKAR1B,PRKAR2B,PRKCD,PRKCZ,PRKDC,PRKN,PRKRIP1,PRR5L,PSCA,PSEN1,PSMD10,PTEN,PTPN1,PTPN22,PTPRJ,PTPRR,PWP1,PYCARD,PYDC1,RANBP9,RAPGEF1,RASSF2,RB1,RGN,RGS14,RGS2,RGS3,RGS4,RNF149,RPS6KA6,RPTOR,RTN4R,RTN4RL2,SAMSN1,SEMA4D,SERPINB3,SFN,SFRP1,SFRP2,SH3BP5,SHB,SIRT1,SIRT2,SIRT3,SLC9A3R1,SLIT2,SMAD4,SMAD7,SMCR8,SMPD1,SMYD3,SNCA,SNX6,SOCS1,SOCS2,SOCS3,SOCS4,SOCS5,SOCS6,SOCS7,SORL1,SPINK1,SPRED1,SPRED2,SPRY1,SPRY2,SPRY4,SRCIN1,STK38,STRAP,SYNJ2BP,TARBP2,TARDBP,TBC1D10C,TERF2IP,TESC,TGFB1,THY1,TIMP3,TLR4,TNFAIP3,TNIP1,TP73,TRAF3IP1,TRIB1,TRIB2,TRIB3,TSC2,TSG101,TWIST1,UBASH3B,UCHL1,UVSSA,VPS25,VRK3,WARS,WEE2,WNK1,WNK2,WWTR1,XDH,YWHAG,ZBED3,ZC3H12A,ZFYVE28,ZNF675	TetrapodAncestor	300
GO.Biological.Process	GO:0001934	positive.regulation.of.protein.phosphorylation	1	1e-300	1e-300	1e-300	1.226015e+0	ABI1,ABL1,ACE,ACKR3,ACSL1,ACVR1B,ACVR2A,ACVR2B,ACVRL1,ADAM8,ADAM9,ADCY2,ADCY3,ADCY4,ADCY5,ADCY8,ADCYAP1,ADIPOQ,ADNP,ADORA1,ADORA2B,ADRA1A,ADRA1B,ADRA2A,ADRA2B,ADRA2C,ADRB2,ADRB3,AFAP1L2,AGER,AGT,AIF1,AJUBA,AKAP13,AKT2,ALK,ALKAL1,ALOX15,ALS2,ANGPT1,ANGPT4,ANKRD6,APLNR,APP,AR,ARAF,AREG,ARHGAP8,ARHGEF2,ARL2BP,ARL6IP5,ARRB1,ARRB2,ATG14,ATM,ATP2B4,ATP6AP1,AVP,AVPI1,AXIN2,BAG4,BAK1,BANK1,BAX,BCAR3,BCL2,BMP10,BMP15,BMP2,BMP4,BMP5,BMP6,BMP7,BMP8A,BMP8B,BMPER,BMPR1A,BMPR2,BRAF,BRAT1,C1QTNF1,C1QTNF2,C3,C5,C8orf4,CAB39,CACUL1,CALCR,CALM1,CALM2,CALM3,CAMK1,CAMKK1,CAMKK2,CAPRIN2,CARD10,CARD14,CARTPT,CAV1,CAV2,CAVIN3,CCDC88A,CCK,CCL1,CCL11,CCL13,CCL14,CCL15,CCL15-CCL14,CCL16,CCL17,CCL18,CCL19,CCL2,CCL21,CCL22,CCL23,CCL3,CCL3L3,CCL4,CCL4L2,CCL5,CCL7,CCL8,CCNB1,CCND1,CCND2,CCND3,CCNH,CCNK,CCNL1,CCNL2,CCNT2,CCR1,CCR7,CD24,CD27,CD36,CD3E,CD40,CD44,CD74,CD80,CD81,CDC25B,CDC42,CDC6,CDH2,CDK1,CDK10,CDK20,CDK5,CDK5R1,CDK5R2,CDK9,CDKN1A,CDKN1B,CDON,CEMIP,CENPE,CFLAR,CHEK2,CHI3L1,CHRNA3,CIB1,CKS1B,CKS2,CLCF1,CLIP3,CLU,CNTF,CNTN1,COPS8,CREBL2,CRK,CRKL,CSF1,CSF1R,CSF3,CSK,CSNK1D,CSNK2B,CSPG4,CTF1,CTGF,CTNNB1,CX3CL1,CXCR4,CYR61,CYSLTR2,DAB1,DAB2,DAB2IP,DAXX,DBF4B,DBNL,DDR2,DDRGK1,DDT,DDX3X,DGKQ,DKK1,DLG1,DNAJC27,DRD2,DRD4,DSTYK,DUSP15,DUSP19,DUSP22,DUSP6,DUSP7,DUSP9,DVL1,DVL3,DYNAP,ECT2,EDA2R,EDAR,EDN1,EDN3,EDNRB,EFNA1,EFNA5,EGF,EGFR,EGR1,EHD4,EIF2AK2,EMP2,ENG,ENPP2,EPGN,EPHA4,EPHA7,EPHA8,EPO,ERBB2,ERBB4,ERCC6,EREG,ERN1,ERN2,ERP29,ETAA1,EZH2,F2,F2R,F2RL1,FAM129A,FAM20A,FAM58A,FAS,FBXO18,FBXW7,FFAR4,FGD2,FGF1,FGF10,FGF13,FGF18,FGF19,FGF2,FGF20,FGF21,FGF23,FGF4,FGF7,FGF9,FGFR1,FGFR2,FGFR3,FGFR4,FGG,FIZ1,FLCN,FLOT1,FLT1,FLT3LG,FLT4,FMR1,FRS2,FSHR,FZD1,FZD10,FZD4,FZD5,FZD7,FZD8,GADD45A,GADD45B,GADD45G,GAREM1,GAS6,GCNT2,GDF1,GDF10,GDF11,GDF2,GDF3,GDF5,GDF6,GFRA2,GH1,GHR,GLIPR2,GNG3,GPER1,GPNMB,GPR183,GPR37,GPR37L1,GPR55,GPRC5B,GREM1,GRM4,GRM5,GSK3A,HACD3,HAND2,HAVCR2,HAX1,HBEGF,HCLS1,HCRTR1,HDAC2,HDAC3,HES1,HES5,HGF,HIPK2,HMGB1,HMGCR,HRAS,HSF1,HSP90AB1,HSPA2,HSPA5,HSPH1,HTR2A,HTR2B,HTR2C,IAPP,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNB1,IFNE,IFNG,IFNK,IFNL1,IFNW1,IGF1,IGF2,IGFBP4,IKBKG,IL12A,IL12B,IL13,IL15,IL18,IL1B,IL2,IL20,IL21,IL23A,IL23R,IL24,IL26,IL31RA,IL34,IL4,IL5,IL6,IL6R,IL6ST,INAVA,INHA,INHBA,INHBB,INS,IQGAP1,IQGAP3,IRAK1,IRGM,ISL1,ITGA1,ITGA5,ITGAV,JAK2,JCAD,JTB,JUN,KARS,KISS1,KITLG,KL,KRAS,KSR1,LACRT,LAMTOR2,LAMTOR3,LAT,LATS1,LCP2,LEFTY1,LEFTY2,LEP,LGALS9,LIF,LPAR1,LPAR3,LRP4,LRP8,LRRK2,LTBR,LYN,MAD2L2,MADD,MALT1,MAP2K2,MAP2K3,MAP2K4,MAP2K6,MAP2K7,MAP3K1,MAP3K10,MAP3K11,MAP3K12,MAP3K13,MAP3K14,MAP3K15,MAP3K19,MAP3K2,MAP3K21,MAP3K3,MAP3K4,MAP3K5,MAP3K6,MAP3K7,MAP3K7CL,MAP3K8,MAP3K9,MAP4K1,MAP4K3,MAP4K4,MAPK1,MAPK10,MAPK11,MAPK14,MAPK3,MAPK8IP1,MAPK8IP3,MAPKAP1,MAPKAPK2,MAPKAPK3,MAPKAPK5,MAPRE3,MARCO,MARK2,MAS1,MID1,MIF,MINK1,MLST8,MMD,MMD2,MMP9,MOB2,MOS,MRE11,MRNIP,MST1R,MSTN,MTCP1,MTOR,MUC20,MUL1,MUSK,MYDGF,NAB2,NBN,NCF1,NCKAP1L,NDRG4,NDST1,NECAB2,NEK1,NEK10,NEK4,NENF,NEURL1,NGF,NKX3-1,NOD1,NOTCH1,NOTCH2,NOX4,NPM1,NPTN,NPY5R,NQO2,NRG1,NRG3,NRK,NRP1,NTF3,NTRK1,NTRK2,NTRK3,OPRD1,OPRK1,OPRL1,OPRM1,OSM,P2RX7,P2RY1,PAK1,PAK2,PAK3,PAK4,PAK5,PARK7,PARP14,PARP16,PARP9,PDCD10,PDE5A,PDE6H,PDE8A,PDGFA,PDGFB,PDGFC,PDGFD,PDGFRB,PDPK1,PEA15,PELI2,PFN2,PHB,PIH1D1,PIK3CA,PIK3CG,PIK3R5,PIK3R6,PIN1,PINK1,PKD1,PKD2,PKN1,PLA2G1B,PLA2G2A,PLA2G5,PLA2G6,PLCB1,PLCE1,PLCG1,PLK1,PPP1R15A,PPP2R3C,PRKAA1,PRKACA,PRKACG,PRKAG2,PRKAR1A,PRKAR1B,PRKAR2B,PRKCA,PRKCD,PRKCE,PRKCZ,PRKD1,PRKD2,PRLR,PRMT1,PROK1,PROK2,PROM2,PROX1,PRR5,PRR5L,PSAP,PSEN1,PSMD10,PTEN,PTK2,PTK2B,PTPN1,PTPN11,PTPN22,PYCARD,RAC1,RAD50,RAF1,RALB,RAP1A,RAP1B,RAP2A,RAP2B,RAP2C,RAPGEF1,RAPGEF2,RAPGEF3,RARRES2,RASGRP1,RASSF2,RB1CC1,RBPMS,RELN,RET,RGCC,RICTOR,RIPK1,RIPK2,RIPK3,RIT2,ROBO1,ROCK2,ROR2,RPS27A,RPS3,RPS6KA4,RPS6KA5,RPTOR,RSPO1,RYK,S100A12,S100A7,SAA1,SASH1,SBK2,SDC4,SDCBP,SEMA4C,SEMA4D,SEMA7A,SFRP2,SHC1,SHC2,SIRT1,SLC11A1,SLC27A1,SLC30A10,SMAD4,SMYD3,SNCA,SNX9,SOCS3,SOD1,SORBS3,SOX2,SOX9,SPAG9,SPDYA,SPHK1,SPN,SPRY2,SQSTM1,SRC,SRCIN1,SSTR4,STAP1,STAP2,STK24,STK26,STK4,STRADA,STRADB,SYK,TAB1,TAB2,TAB3,TAOK1,TAOK2,TBK1,TBX1,TCL1A,TCL1B,TDGF1,TEC,TEK,TELO2,TENM1,TERF2IP,TGFB1,TGFB2,TGFBR1,TGFBR2,THBS1,THBS4,THPO,TIAM1,TIMP2,TIRAP,TLR3,TLR4,TLR6,TLR9,TMEM189-UBE2V1,TNF,TNFAIP8L3,TNFRSF10A,TNFRSF10B,TNFRSF11A,TNFRSF14,TNFRSF18,TNFRSF19,TNFRSF1A,TNFSF11,TNFSF15,TNFSF18,TNIK,TNK2,TNKS1BP1,TOM1L1,TP53,TP73,TPD52L1,TPX2,TRAF2,TRAF4,TRAF6,TRAF7,TREM2,TRIM5,TRIM6,TRPC5,TRPC6,TTK,TXN,UBC,UBE2N,UCN,UNC119,UNC5CL,VANGL2,VAPB,VEGFA,VEGFC,VLDLR,VTN,WDFY2,WNK1,WNK3,WNT1,WNT11,WNT16,WNT3A,WNT5A,WNT7A,WNT7B,WWC1,XCL1,XCL2,XDH,XRCC5,XRCC6,YES1,ZC3H12A,ZFP91,ZNF622	TetrapodAncestor	300
GO.Biological.Process	GO:0001944	vasculature.development	1	1e-300	1e-300	1e-300	1.276168e+0	AAMP,ACKR3,ACTA2,ACVR2B,ACVRL1,ADAM15,ADAM8,ADAMTS9,ADGRA2,ADGRG1,ADIPOR2,ADM2,AGGF1,AHR,AMOT,ANGPT1,ANGPT2,ANGPT4,ANGPTL4,ANKRD17,ANPEP,ANTXR1,AP2B1,APOB,APOD,APOE,APOLD1,AQP1,ARHGAP22,ARHGAP24,ARID1A,ARID2,ATPIF1,B4GALT1,B9D1,BAK1,BAX,BCAS3,BMP4,BMPER,BMPR1A,BMPR2,C1GALT1,C5orf42,CALCRL,CAV1,CCBE1,CCL2,CCM2,CD34,CDC42,CDH13,CDH2,CDH5,CHD7,CIB1,CITED1,COL15A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL8A1,COL8A2,CRKL,CSPG4,CTGF,CTNNB1,CUL7,CX3CL1,CXCL8,CXCR3,CYP1B1,CYR61,DAB2IP,DCTN5,DHCR7,DLL1,DLL4,DLX3,DNM2,DYNC2H1,E2F7,E2F8,ECSCR,EDN1,EFNA1,EFNB2,EGF,EGFL7,EGR1,EGR3,EIF2AK3,ELK3,ENG,ENPEP,ENSG00000259753,EPAS1,EPC1,EPGN,EPHA1,EPHA2,EPHB1,EPHB2,EPHB3,EPHB4,ERAP1,EREG,ERRFI1,ESM1,ETS1,EYA1,FBXW7,FBXW8,FGF1,FGF10,FGF18,FGF2,FGF6,FGF9,FGFR1,FGFR2,FLT1,FLT4,FLVCR1,FMNL3,FN1,FOSL1,FOXC1,FOXC2,FOXF1,FOXH1,FOXN1,FOXO1,FOXS1,FZD4,FZD5,FZD8,GAB1,GATA6,GBX2,GDF2,GGNBP2,GJA4,GJC1,GLI3,GNA13,GPC3,GPLD1,GPR4,GREM1,HAND1,HAND2,HAS2,HDAC7,HEG1,HES1,HEY1,HEY2,HHEX,HIF1A,HIF3A,HMOX1,HOXA1,HPGD,HPSE,HRG,HS6ST1,HSPG2,ID1,IHH,IL18,IMMP2L,ITGA5,ITGAV,ITGB1,ITGB8,JAG1,JAM3,JMJD6,JUN,JUNB,KLF5,KRIT1,LAMA5,LEF1,LEMD3,LEP,LEPR,LGALS8,LIF,LOX,LOXL1,LOXL2,LRP1,LRP5,LUZP1,LYL1,MAP3K3,MAPK1,MAPK14,MCAM,MDM2,MEF2C,MEGF8,MEIS1,MEOX2,MESP1,MFGE8,MIB1,MMP14,MMP19,MMRN2,MYDGF,MYH9,MYLK,MYO1E,MYOCD,NAA15,NCL,NDNF,NDP,NDST1,NF1,NFATC4,NKX2-5,NKX3-1,NOG,NOS3,NOTCH1,NOTCH3,NOTCH4,NOV,NOX5,NPRL3,NR4A1,NRP1,NRP2,NSDHL,NTRK2,NUS1,OSR1,OTULIN,OVOL2,PAXIP1,PCSK5,PDCD10,PDCD6,PDCL3,PDGFA,PDGFB,PDGFRB,PDPN,PECAM1,PIK3CA,PIK3CG,PIK3R6,PITX2,PKD1,PKD2,PKNOX1,PLCD3,PLG,PLXDC1,PLXND1,PPP3CB,PRCP,PRDM1,PRICKLE1,PRKCA,PRKD1,PRKD2,PRKX,PROK1,PROK2,PROP1,PROX1,PRRX1,PSEN1,PTEN,PTK2,PTK2B,PTK7,PTPN14,PTPRB,QKI,RAMP1,RAMP2,RAPGEF1,RAPGEF2,RAPGEF3,RASA1,RASIP1,RBPJ,RECK,RHOJ,RIC8A,RNF213,ROBO1,ROBO4,ROM1,RSPO3,S100A7,S1PR1,SAT1,SCG2,SEC24B,SEMA3C,SEMA3E,SEMA4A,SEMA5A,SETD2,SFRP2,SGCB,SGPL1,SH2D2A,SHB,SHC1,SIRT1,SLC12A6,SLIT2,SMAD7,SMO,SNX17,SOCS3,SOS1,SOX17,SOX18,SOX4,SPHK1,SPHK2,SPI1,SPINT1,SPRED1,SRF,SRPK2,SRPX2,STAB2,STK4,STRA6,SUFU,SYK,T,TAB1,TAL1,TBX1,TBX2,TBX20,TBX3,TBX5,TCF21,TDGF1,TEAD2,TEK,TFAP2B,TGFB1,TGFB2,TGFBI,TGFBR1,TGFBR2,THBS1,THSD7A,THY1,TIE1,TIPARP,TMED2,TMEM100,TMEM2,TMEM204,TMEM231,TMPRSS6,TNFRSF12A,TNFSF12,TNNI3,TSPAN12,TYMP,UBP1,UNC5B,VASH1,VASH2,VAV2,VAV3,VEGFA,VEGFB,VEGFC,VEGFD,VEZF1,VHLL,WARS,WARS2,WASF2,WNT11,WNT7A,WNT7B,XBP1,ZBTB14,ZC3H12A,ZFAND5,ZFP36L1,ZFPM2,ZMIZ1	TetrapodAncestor	300
GO.Biological.Process	GO:0002520	immune.system.development	1	1e-300	1e-300	1e-300	1.301305e+0	ABI1,ABL1,ACE,ACIN1,ACTN1,ADA,ADAR,ADD1,ADGRG3,AGPAT5,AICDA,ANGPT1,ANLN,ANXA1,APP,ARHGEF7,ARID4A,ARMC6,ARTN,ASH2L,ASXL1,ATG5,ATM,ATP11C,ATPIF1,AXL,AZI2,BABAM1,BAK1,BARX1,BATF2,BATF3,BAX,BCL11B,BCL2,BCL2L11,BCL3,BCL6,BCR,BLNK,BMI1,BMP4,BMX,BRAF,BTK,CACNA1C,CAMK4,CARD11,CASP3,CASP8,CASP9,CBFB,CCL19,CCR4,CCR6,CCR7,CCR9,CD109,CD164,CD1D,CD28,CD34,CD3D,CD3E,CD74,CD79B,CD86,CD8A,CDC42,CDK13,CDK6,CDKN1C,CDKN2B,CEBPA,CEBPD,CEBPE,CEBPG,CHD2,CHD7,CIAPIN1,CIB1,CITED2,CLCF1,CLEC1B,CLEC4D,CLEC4E,CMTM7,COL24A1,CR2,CRIP2,CRKL,CSF1,CSF1R,CSF3,CTNNB1,CTNNBL1,CUL4A,CXCL13,CXCR5,DACT2,DCAF1,DCLRE1C,DHRS2,DHTKD1,DLL1,DLL4,DMTN,DNAJA3,DNASE2,DOCK10,DOCK11,DOCK2,DYRK3,EEF2,EFNA4,EGR1,EML1,EOMES,EP300,EPAS1,EPHA2,EPHB3,EPO,ERCC1,ERCC2,ESCO2,ETV6,EXO1,EXOSC3,EXOSC6,F2RL1,FADD,FAM20C,FAM210B,FAS,FCER1G,FGF10,FGFR2,FLCN,FLI1,FLT3LG,FLVCR1,FOXE1,FOXJ1,FOXL1,FOXN1,FOXP3,FST,FSTL3,FUT10,FUT7,FZD5,FZD7,FZD8,FZD9,G6PD,GAB2,GAS6,GATA2,GATA3,GLI3,GLO1,GLRX5,GON4L,GPC3,GPR18,GPR183,HAND2,HAVCR2,HBZ,HCLS1,HDAC4,HDAC5,HDAC9,HEATR9,HES1,HHEX,HIF1A,HIPK1,HIPK2,HMGB1,HMGB2,HNF1A,HSPA9,ICOS,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNB1,IFNE,IFNG,IFNK,IFNW1,IKZF1,IL10,IL12B,IL15,IL18R1,IL2,IL31RA,IL4,IL6,IL7,IL7R,INHA,INHBA,IRF1,IRF4,IRF8,ITFG2,ITGA4,ITGB1,ITK,ITM2A,ITPKB,JAG1,JAG2,JAGN1,JAK2,JAK3,JAM3,JARID2,JMJD6,JUN,JUNB,KAT6A,KAT8,KCNAB2,KDELR1,KIRREL3,KITLG,KLF1,KLF2,KLF4,KLF6,KMT2E,KRT75,L3MBTL1,L3MBTL3,LCK,LEF1,LEP,LEPR,LFNG,LGALS1,LGALS9,LIG4,LMO4,LRP5,LRRC17,LRRC8A,LTB,LTBR,LY6D,LYL1,LYN,MAD1L1,MAEA,MAFB,MALT1,MAPK1,MAPK14,MAPK3,MB,MECOM,MEF2C,MEIS1,MELK,MEOX1,MERTK,MFAP5,MFNG,MIXL1,MKNK2,MLF1,MLH1,MMP9,MSH2,MSH3,MSH6,MYH9,MYO1E,NARFL,NBEAL2,NBN,NCKAP1L,NCOA6,NFAM1,NFKB2,NHEJ1,NKX2-3,NKX2-5,NKX3-2,NOTCH2,NOTCH4,NTRK1,OCSTAMP,ONECUT1,OSTM1,PAFAH1B1,PAPD4,PARP1,PATZ1,PBX1,PCID2,PDE1B,PDPN,PGM3,PICALM,PIK3CD,PIK3R1,PIP4K2A,PIR,PITX2,PKN1,PKNOX1,PLA2G2D,PLCG2,PLCL2,PLEK,PML,POLB,POLL,POLM,POLQ,POU1F1,POU2F2,PPARG,PPP2R3C,PPP3CB,PRDX3,PREX1,PRKDC,PRKX,PSEN1,PSMB11,PTBP3,PTGER4,PTK2B,PTPN11,PTPN22,PTPRZ1,RAF1,RAG1,RAG2,RASGRP4,RB1,RBM47,RBPJ,RC3H1,RC3H2,RELB,REST,RET,RHAG,RIPK3,RNF168,RNF8,ROGDI,RORC,RPS14,RPS6,RRAS,RSAD2,RTKN2,RUNX1,RUNX2,SATB1,SBDS,SEMA4A,SERPINB12,SFRP1,SFRP2,SFXN1,SGPL1,SH2B3,SH3PXD2A,SHB,SIPA1L3,SIRT1,SLAMF6,SLC25A38,SLC40A1,SLC46A2,SLC7A6OS,SLC8A3,SMAD5,SMPD3,SNRK,SNX10,SOD1,SOX4,SP7,SPI1,SPN,SPNS2,SRC,SRF,SSBP3,STAT6,STK4,STON2,SYK,TAL1,TAZ,TBX1,TCF21,TCF3,TEK,TESC,TET2,TFRC,TGFB1,TGFB2,TGFBR1,TGFBR2,THEMIS,THOC5,THPO,THRA,TIPARP,TIRAP,TLR2,TMEM91,TMOD3,TNF,TNFAIP3,TNFRSF11A,TNFRSF13B,TNFSF11,TNFSF8,TOP2A,TPD52,TPO,TRAF6,TREM2,TROVE2,TRPM2,TSPAN2,TTC7A,TYR,TYRO3,UNG,VAV1,VCAM1,VEGFA,VPS33B,WASF2,WDR1,WDR7,WDR78,WNT1,WNT10B,WNT3A,WNT4,WNT5A,XRCC5,ZAP70,ZBTB1,ZBTB16,ZBTB24,ZFAT,ZFP36L1,ZFP36L2,ZFPM1,ZNF160,ZNF385A,ZNF683,ZNF784	TetrapodAncestor	300
GO.Biological.Process	GO:0002684	positive.regulation.of.immune.system.process	1	1e-300	1e-300	1e-300	1.297835e+0	ABI1,ABL1,ACIN1,ACTR2,ACTR3,ACVR1B,ACVR2A,ADA,ADAM8,ADGRE2,ADORA2B,AGER,AIF1,ANKRD17,ANKRD54,ANO6,ANXA1,AP1G1,AP3D1,APOB,APP,AQP3,ARG1,ARPC1A,ARPC1B,ARPC2,ARPC4,ARPC5,ATAD5,ATP11C,ATP6AP1,ATXN1L,AXL,BAD,BAG6,BAX,BCAR1,BCL10,BCL2,BCL6,BDKRB1,BIRC2,BIRC3,BLK,BRAF,BST1,BTK,BTLA,BTRC,C12orf4,C1QA,C1QB,C1QBP,C1QC,C3,C3AR1,C4A,C4B,C4BPA,C4BPB,C5,C6,C7,C8A,C8B,C8G,C9,CA2,CADM1,CALR,CAMK1D,CARD11,CASP8,CAV1,CCDC88B,CCL1,CCL19,CCL2,CCL21,CCL3,CCL4,CCL5,CCL7,CCL8,CCR1,CCR2,CCR6,CCR7,CD101,CD14,CD180,CD19,CD1D,CD2,CD209,CD226,CD24,CD247,CD27,CD274,CD276,CD28,CD300A,CD300LF,CD320,CD36,CD38,CD3D,CD3E,CD3G,CD40,CD46,CD47,CD5,CD55,CD59,CD6,CD74,CD79B,CD80,CD81,CD83,CD86,CDC42,CDKN1A,CFH,CFHR1,CFHR5,CFI,CFP,CHRNB2,CHUK,CLCF1,CLEC4A,CLEC4C,CLEC4D,CLEC4E,CLEC6A,CLEC7A,CLECL1,CLU,CMKLR1,CMTM3,CNPY3,CNR1,COLEC10,COLEC11,COLEC12,CORO1A,CR1,CR2,CREB1,CREB3,CRK,CRTAM,CSF1,CSF3,CSK,CTLA4,CTSB,CTSL,CUL1,CXCL1,CXCL10,CXCL11,CXCL13,CXCL14,CXCL2,CXCL3,CXCL5,CXCL6,CXCL8,CXCL9,CYBA,CYFIP1,CYFIP2,DAPK2,DDX58,DDX60,DENND1B,DHPS,DHX9,DMBT1,DNAJA3,DOCK8,DUSP10,EBI3,EDN1,EDN2,EDN3,EFNB1,EFNB2,EFNB3,EIF2AK4,ELMO1,ELMO2,ENSG00000173366,EP300,EPO,EREG,ETS1,EXOSC3,EXOSC6,F2RL1,F7,FADD,FAM19A3,FAM210B,FAM49B,FBXW11,FCER1G,FCER2,FCN1,FCN2,FCN3,FER,FES,FFAR2,FFAR3,FGF10,FGG,FGR,FLOT1,FLOT2,FLT3LG,FOS,FOXC1,FOXF1,FOXJ1,FOXP3,FYB1,FYB2,FZD5,GAB2,GAS6,GATA2,GATA3,GLI2,GLI3,GNAS,GPAM,GPLD1,GPR183,GPR32,GPR33,GPR68,GPRC5B,GPSM3,GRAP2,GRB2,HAVCR2,HAX1,HCK,HCLS1,HES1,HEXIM1,HHLA2,HIF1A,HLX,HMGB1,HMGB2,HMOX1,HMSD,HRAS,HRG,HSP90AB1,HSP90B1,HSPH1,ICAM2,ICOS,IDO1,IFNB1,IFNG,IFNK,IFNL1,IFNL2,IFNL3,IGF1,IGF2,IGFBP2,IGLL1,IGLL5,IHH,IKBKB,IKBKE,IKBKG,IL10,IL12A,IL12B,IL12RB1,IL13,IL13RA2,IL15,IL17A,IL18,IL18RAP,IL1A,IL1B,IL1R1,IL1RL1,IL1RL2,IL2,IL20,IL21,IL23A,IL23R,IL27RA,IL33,IL34,IL36B,IL4,IL5,IL6,IL6R,IL6ST,IL7,IL7R,INAVA,INHBA,INPP5D,IRAK1,IRAK3,IRAK4,IRF3,IRF7,IRGM,IRS2,ISG15,ITCH,ITGA2,ITGA2B,ITGA4,ITGAM,ITGB2,ITK,ITPKB,JAG1,JAK3,JUN,KARS,KIRREL1,KITLG,KLF10,KLHL6,KLRK1,KRAS,KRT1,LAT,LAT2,LAX1,LBP,LCK,LCP2,LEF1,LEP,LGALS1,LGALS3,LGALS9,LGMN,LIF,LILRB2,LILRB4,LIMK1,LRRC70,LY96,LYN,MADCAM1,MALT1,MAP2K6,MAP3K1,MAP3K14,MAP3K7,MAP3K8,MAPK1,MAPK14,MAPK3,MAPKAPK2,MAPKAPK3,MARCO,MASP1,MASP2,MATR3,MB21D1,MBL2,MEF2C,MIA3,MIF,MLH1,MMP12,MMP14,MOSPD2,MSH2,MSH6,MUC1,MUC12,MUC13,MUC15,MUC20,MUC3A,MUC4,MUC5AC,MUC5B,MUC6,MUCL1,MYB,MYO10,MYO18A,MYO1C,MYO1G,MZB1,NCK1,NCK2,NCKAP1,NCKAP1L,NCR3,NECTIN2,NFAM1,NFATC2,NFKB1,NLRC4,NLRC5,NLRP10,NOD1,NPHS1,NR1H3,NR1H4,NR4A3,NRAS,NSD2,OCSTAMP,OTULIN,P2RX7,PAG1,PAK1,PAK2,PAK3,PARK7,PARP9,PAXIP1,PCID2,PDCD1,PDCD1LG2,PDCD2,PDE4B,PDE4D,PDGFD,PDPK1,PELI1,PF4,PF4V1,PGC,PGLYRP1,PGLYRP2,PGLYRP3,PGLYRP4,PHB,PIK3AP1,PIK3C3,PIK3CA,PIK3CD,PIK3R1,PIK3R2,PIK3R6,PLA2G1B,PLA2G6,PLA2G7,PLCG1,PLCG2,PLD2,PLEKHA1,PLPP4,PLSCR1,PLVAP,PNP,POLR3B,POLR3C,POLR3D,POLR3F,POU4F1,PPARGC1B,PPBP,PPP2R3C,PQBP1,PRDM1,PRKACA,PRKACG,PRKCA,PRKCB,PRKCD,PRKCE,PRKCH,PRKCQ,PRKCZ,PRKD2,PRKDC,PRMT1,PSEN1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PSPC1,PTAFR,PTK2,PTK2B,PTPN11,PTPN22,PTPRJ,PYCARD,RAB29,RAB7B,RAC1,RAC2,RAF1,RAG1,RAP1A,RAPGEF1,RARA,RARRES2,RASAL3,RASGRP1,RB1,RBCK1,RBM14,RBP4,REG3G,RELA,RELB,RFTN1,RFTN2,RGCC,RIF1,RIOK3,RIPK1,RIPK2,RIPOR2,RNF31,ROR2,RPS27A,RPS3,RPS6KA3,RPS6KA5,RSAD2,RUNX1,S100A1,S100A14,S100A7,S100A8,S100A9,SART1,SASH3,SCIN,SELENOK,SELP,SEMA7A,SERPING1,SFPQ,SH2D1A,SH2D1B,SHB,SIRPG,SIRT1,SKAP2,SLA2,SLAMF6,SLC11A1,SLC39A10,SLC9B2,SMAP1,SNAI3,SNX4,SOCS1,SOCS5,SPACA3,SPG21,SPN,SPON2,SPPL3,SRC,STAP1,STAT1,STAT6,STX4,STX7,STXBP1,STXBP2,STYK1,SUSD4,SYK,TAB1,TAB2,TAB3,TAC1,TAL1,TBK1,TEC,TESC,TESPA1,TFRC,TGFB1,TGFB2,TGFBR2,THBS1,THBS4,THEMIS,THEMIS2,THPO,THY1,TICAM1,TICAM2,TIRAP,TLR1,TLR10,TLR2,TLR3,TLR4,TLR5,TLR6,TLR9,TMEM173,TMEM189-UBE2V1,TMEM64,TMIGD2,TNF,TNFAIP3,TNFRSF13C,TNFRSF14,TNFRSF18,TNFRSF21,TNFRSF4,TNFSF11,TNFSF13,TNFSF13B,TNFSF14,TNFSF18,TNFSF9,TNIP1,TNIP2,TNIP3,TRAF2,TRAF3,TRAF6,TRAT1,TREM2,TREML4,TRIB1,TRIL,TRIM5,TRIM6,TXK,UBC,UBE2D1,UBE2D2,UBE2D3,UBE2N,UNC93B1,UNG,VAMP8,VAV1,VAV2,VAV3,VCAM1,VEGFA,VEGFB,VEGFC,VEGFD,VNN1,VSIG4,VTCN1,WASF2,WDFY1,WIPF2,WIPF3,WNT3A,WNT5A,XBP1,XCL1,XRCC5,XRCC6,YES1,ZAP70,ZBTB1,ZBTB16,ZFP36L1,ZMIZ1,ZNF16,ZNF335,ZNF580,ZP3,ZP4	TetrapodAncestor	300
GO.Biological.Process	GO:0002694	regulation.of.leukocyte.activation	1	1e-300	1e-300	1e-300	1.342480e+0	ABL1,ABR,ADA,ADAM8,ADGRE2,ADGRF5,ADORA2A,ADORA2B,AGER,AHR,AIF1,ANXA1,AP1G1,AP3D1,APLF,APP,ARG1,ARG2,ATAD5,ATM,ATP11C,AXL,BAD,BANK1,BCL10,BCL2,BCL6,BCR,BMP4,BPI,BRAF,BST1,BTK,BTLA,C12orf4,CAMK4,CARD11,CASP3,CAV1,CBFB,CCDC88B,CCL19,CCL2,CCL21,CCL5,CCR2,CCR7,CD1D,CD2,CD209,CD226,CD24,CD247,CD27,CD274,CD276,CD28,CD300A,CD300LF,CD320,CD38,CD3D,CD3E,CD3G,CD40,CD46,CD47,CD5,CD55,CD59,CD6,CD74,CD80,CD81,CD83,CD86,CDC42,CDKN1A,CEBPB,CHRNB2,CLC,CLCF1,CLEC4G,CLECL1,CNR1,CNR2,CORO1A,CR1,CSK,CTLA4,CTNNB1,CYP26B1,DHPS,DLG1,DLG5,DNAJA3,DOCK8,DROSHA,DTX1,DUSP10,DUSP22,DUSP3,EBI3,EFNB1,EFNB2,EFNB3,EPO,ERBB2,EXOSC3,EXOSC6,F2RL1,FADD,FAM19A3,FAM49B,FANCA,FAS,FBXO7,FCER1G,FER,FES,FGF10,FGR,FLOT2,FLT3LG,FOXF1,FOXJ1,FOXN1,FOXP3,GAB2,GAL,GAS6,GATA2,GATA3,GLI2,GLI3,GNRH1,GPAM,GPER1,GPNMB,GPR183,GRAP2,GRB2,GSN,HAVCR2,HES1,HHLA2,HLX,HMGB1,HMGB3,HMOX1,HSPH1,ICOS,IDO1,IFNA2,IFNB1,IFNG,IFNL1,IFNL2,IFNL3,IGF1,IGF2,IGFBP2,IGLL1,IGLL5,IHH,IKZF3,IL10,IL12A,IL12B,IL12RB1,IL13,IL13RA2,IL15,IL18,IL1B,IL1RL1,IL1RL2,IL2,IL20RB,IL21,IL23A,IL23R,IL27,IL27RA,IL31RA,IL33,IL36B,IL4,IL5,IL6,IL6ST,IL7,IL7R,INHA,INHBA,INPP5D,IRF1,IRF4,IRS2,ITCH,ITGAM,ITGB2,ITPKB,JAK3,KARS,KIRREL1,KLRK1,LAT,LAX1,LBP,LCK,LDLR,LEP,LGALS1,LGALS3,LGALS9,LILRB2,LILRB4,LOXL3,LRRC32,LST1,LYN,MAD1L1,MALT1,MAP3K14,MAP3K7,MAP3K8,MEF2C,MERTK,METTL3,MIF,MILR1,MLH1,MMP14,MSH2,MSH6,MYB,MYO18A,MZB1,NCK1,NCK2,NCKAP1L,NDFIP1,NECTIN2,NFAM1,NFATC2,NFKBID,NPHS1,NR1H3,NR4A3,NSD2,PAG1,PAK1,PAK2,PAK3,PAWR,PAXIP1,PCID2,PDCD1,PDCD1LG2,PDE5A,PDPK1,PELI1,PGLYRP1,PGLYRP2,PGLYRP3,PIK3CA,PIK3R1,PIK3R6,PKN1,PLA2G10,PLA2G2D,PLA2G2F,PLSCR1,PNP,PPP2R3C,PRAM1,PRDM1,PRELID1,PRKAR1A,PRKCQ,PRKCZ,PTAFR,PTPN11,PTPN22,PYCARD,RAC1,RAC2,RAG1,RARA,RASAL3,RASGRP1,RC3H1,RHBDD3,RIF1,RIPK2,RIPK3,RIPOR2,RNF41,RPS3,RUNX1,SAMSN1,SART1,SASH3,SCGB1A1,SDC4,SELENOK,SFRP1,SHB,SHPK,SIRPG,SIT1,SLA2,SLC39A10,SLC46A2,SMAD7,SNCA,SNX4,SOCS1,SOCS5,SOCS6,SOD1,SOS1,SOX11,SOX13,SPACA3,SPINK5,SPN,SRC,STAP1,STAT6,STX4,STXBP1,STXBP2,STYK1,SYK,TAC1,TARM1,TBC1D10C,TESPA1,TFRC,TGFB1,TGFBR2,THBS1,THOC1,THY1,TICAM1,TIGIT,TIRAP,TLR4,TLR6,TLR9,TMEM131L,TMIGD2,TNFAIP3,TNFAIP8L2,TNFRSF13B,TNFRSF13C,TNFRSF14,TNFRSF18,TNFRSF21,TNFRSF4,TNFSF11,TNFSF13,TNFSF13B,TNFSF14,TNFSF18,TNFSF9,TNIP2,TRAF2,TRAF6,TSPAN32,TYRO3,UNG,VAMP8,VAV1,VAV3,VCAM1,VNN1,VSIG4,VTCN1,WNT3A,WNT5A,XBP1,XCL1,YES1,ZAP70,ZBTB1,ZBTB16,ZBTB7B,ZC3H12A,ZC3H8,ZEB1,ZFP36L1,ZFP36L2,ZMIZ1,ZNF335,ZNF683,ZP3,ZP4	TetrapodAncestor	300
GO.Biological.Process	GO:0007167	enzyme.linked.receptor.protein.signaling.pathway	1	1e-300	1e-300	1e-300	1.254040e+0	ABI1,ABL1,ABL2,ACTR2,ACTR3,ACVR1B,ACVR2A,ACVR2B,ACVRL1,ADAM9,ADRB2,AFP,AHI1,AKAP3,AKAP4,AKT1S1,AKT2,ALK,AMH,AMHR2,ANGPT1,ANGPT2,ANGPT4,ANGPTL1,ANOS1,AP2A1,AP2A2,AP2B1,AP2M1,AP2S1,AP3S1,APC,APELA,APH1A,APH1B,APPL1,AREG,ARHGEF7,ARID5B,ARPC1A,ARPC1B,ARPC2,ARPC4,ARPC5,ARRB2,ATOH8,ATP6AP1,ATP6V0A4,ATP6V0B,ATP6V0C,ATP6V0D1,ATP6V0D2,ATP6V0E1,ATP6V0E2,ATP6V1B1,ATP6V1B2,ATP6V1C1,ATP6V1C2,ATP6V1D,ATP6V1E1,ATP6V1E2,ATP6V1G1,ATP6V1G3,ATP6V1H,AXL,BAIAP2L2,BAMBI,BCAR1,BCR,BDKRB2,BDNF,BLK,BLNK,BMP10,BMP15,BMP2,BMP4,BMP5,BMP6,BMP7,BMP8A,BMP8B,BMPR1A,BMPR1B,BMPR2,BMX,BTBD11,BTC,BTK,C2CD5,CASP3,CAV2,CBL,CBLB,CCL2,CD3E,CD3EAP,CD7,CD8A,CD8B,CDC42,CDH5,CDK5R1,CEP57,CER1,CGN,CHRD,CHRDL1,CHRNA3,CITED1,CITED2,CLDN5,CLNK,CNKSR1,CNPY2,COL1A1,COL1A2,COL3A1,COL4A3,COL4A5,CPNE3,CREB1,CRIM1,CRK,CSF1,CSF1R,CSH1,CSK,CSPG4,CSRNP1,CTF1,CTGF,CUL5,CYBA,CYBB,CYFIP1,CYFIP2,DAB2IP,DDIT4,DDR1,DDR2,DDX5,DGKD,DGKQ,DLX5,DNM1,DOK1,DOK2,DOK5,DSG4,DUSP15,DUSP22,EFEMP1,EFNA1,EFNA3,EFNA4,EFNA5,EFNB1,EFNB2,EFNB3,EGF,EGFR,EGR1,EID2,EIF2AK3,EIF4EBP1,ELMO1,ELMO2,ENG,ENSG00000144785,ENSG00000251246,ENSG00000278139,ENSG00000282278,EPHA1,EPHA10,EPHA2,EPHA3,EPHA4,EPHA5,EPHA6,EPHA7,EPHA8,EPHB1,EPHB2,EPHB3,EPHB4,EPHB6,EPS15,EPS8,ERBB2,ERBB4,EREG,ESRP1,ESRP2,F11R,FAM83B,FAM83G,FAT4,FER,FERMT2,FES,FGF1,FGF10,FGF12,FGF16,FGF17,FGF18,FGF19,FGF2,FGF20,FGF21,FGF22,FGF23,FGF3,FGF4,FGF6,FGF7,FGF9,FGFBP1,FGFR1,FGFR2,FGFR3,FGFR4,FGFRL1,FGR,FIBP,FKBP1A,FLRT1,FLRT2,FLRT3,FLT1,FLT4,FMOD,FNTA,FOS,FOXC1,FOXC2,FOXH1,FOXO1,FOXO4,FRK,FRS2,FRS3,FSHB,FSTL1,FURIN,FUT8,GAB1,GAB2,GAREM1,GAS6,GCNT2,GDF1,GDF10,GDF11,GDF2,GDF3,GDF5,GDF6,GFRA1,GFRA2,GFRA4,GH1,GH2,GHR,GIGYF1,GIGYF2,GP6,GPLD1,GRAP,GRAP2,GRB10,GRB2,GRB7,GREM1,GREM2,GRIN1,GRIN2B,GSK3A,GTF2F1,GTF2F2,GUCA1B,GUCY2C,GUCY2D,GUCY2F,HAP1,HBEGF,HCK,HFE2,HGF,HIPK2,HNF4A,HNRNPH1,HNRNPM,HPGD,HPN,HRAS,HSPB1,ID1,IDE,IGF1,IGF1R,IGF2,IGF2R,IL31RA,IL6ST,INHA,INHBA,INHBB,INS,INSRR,IQGAP1,IRAK1,IRS1,IRS2,IRS4,ITGAV,ITGB5,ITK,ITSN1,JAK2,JAK3,JUN,KALRN,KIF16B,KL,KLF10,KRAS,LCK,LCP2,LEF1,LEFTY1,LEFTY2,LIF,LIFR,LNPEP,LRP4,LTBP4,LTK,LYN,MAGI2,MAP3K7,MAPK1,MAPK11,MAPK13,MAPK14,MAPK3,MAPKAPK2,MAPKAPK3,MATK,MEGF8,MET,MMP9,MPZL1,MST1,MST1R,MSTN,MSX1,MSX2,MTMR4,MTSS1,MUC20,MUSK,MVP,MYO1C,MYO1E,NCBP1,NCBP2,NCF1,NCF2,NCF4,NCK1,NCK2,NCKAP1,NCKAP1L,NCSTN,NDEL1,NDST1,NEDD8,NGEF,NGF,NGFR,NKX2-5,NLK,NOG,NPPC,NPR1,NPR2,NRAS,NRG1,NRG2,NRG3,NRG4,NRP1,NRP2,NRTN,NTF3,NTF4,NTRK1,NTRK2,NTRK3,PAG1,PAK1,PAK2,PAK3,PARD3,PARD6A,PARP1,PDCD6,PDGFA,PDGFB,PDGFC,PDGFD,PDGFRB,PDGFRL,PDK2,PDPK1,PDZD3,PHIP,PIGR,PIK3C2A,PIK3CA,PIK3R1,PIK3R2,PIK3R3,PLAT,PLCB1,PLCE1,PLCG1,PLEKHA1,PML,POLR2A,POLR2B,POLR2C,POLR2D,POLR2F,POLR2G,POLR2H,POLR2I,POLR2J,POLR2L,PPM1L,PRKCA,PRKCZ,PRKD1,PRKD2,PRL,PRLR,PSEN1,PSEN2,PSENEN,PTEN,PTK2,PTK2B,PTN,PTPN1,PTPN11,PTPN12,PTPRA,PTPRD,PTPRG,PTPRJ,PTPRK,PTPRR,PTPRT,PTPRU,PXN,RAB14,RAC1,RAF1,RAPGEF1,RAPGEF2,RASA1,RASGRP4,RASSF2,RBFOX2,RBM14,REPS2,RET,RGMA,RGMB,RGS14,RHOQ,ROCK2,ROR2,ROS1,RPE65,RPS27A,RPS6KA5,RUNX2,RYR2,SCX,SDC2,SDCBP,SETX,SGPL1,SH2B2,SH2D2A,SH2D6,SHB,SHC1,SHC2,SHC3,SHCBP1,SIPA1L1,SIRT2,SKI,SKIL,SLA,SLA2,SLC2A8,SLC30A10,SLC33A1,SMAD2,SMAD4,SMAD5,SMAD7,SMARCC1,SMURF1,SMURF2,SOCS2,SOCS5,SOCS7,SOGA1,SORBS1,SOS1,SOSTDC1,SOX9,SPRED1,SPRED2,SRC,SREBF1,SS18,STAP1,STMN1,STUB1,STXBP4,STYK1,SUB1,SULF2,SYK,T,TAB1,TCIRG1,TEC,TEK,TGFB1,TGFB1I1,TGFB2,TGFBR1,TGFBR2,TGFBRAP1,TGIF2,TIA1,TIAL1,TIAM1,TIPARP,TMEM100,TNK2,TRAT1,TRIM71,TRIO,TSC2,TXK,TXNIP,UBASH3B,UBC,UBE2D1,UBE2D3,UBE2M,USP15,USP9X,USP9Y,VAV1,VAV2,VAV3,VEGFA,VEGFB,VEGFC,VEGFD,VIL1,VIM,WASF2,WNT1,YES1,ZAP70,ZCCHC12,ZFAND5,ZFYVE16,ZFYVE27,ZNF106,ZNF8,ZYX	TetrapodAncestor	300
GO.Biological.Process	GO:0008284	positive.regulation.of.cell.proliferation	1	1e-300	1e-300	1e-300	1.218355e+0	ABL1,ACER2,ACER3,ACVRL1,ADA,ADCYAP1,ADGRG1,ADRA1D,ADRA2A,AGER,AGGF1,AGT,AGTR2,AIF1,AKIRIN2,AKR1B1,AKT2,ALDH3A1,ANXA1,APLN,AQP1,AR,AREG,ARG1,ARNT2,ASCL1,ASH2L,ASPM,ATAD5,ATF3,ATXN1L,AVP,AVPR1A,AVPR2,B4GALT1,BAD,BAMBI,BCL2,BCL2L1,BCL6,BIRC5,BIRC6,BMI1,BMP10,BMP2,BMP4,BMP5,BMP6,BMPR1A,BMPR2,BNC1,BST1,BTC,CACUL1,CALCRL,CALR,CAPN1,CARD11,CARM1,CASR,CAV2,CAV3,CBX8,CCDC88B,CCK,CCKBR,CCL11,CCL14,CCL19,CCL2,CCL5,CCNA2,CCNB1,CCND1,CCND2,CCR2,CCR3,CD1D,CD209,CD24,CD274,CD276,CD28,CD320,CD38,CD3E,CD40,CD46,CD47,CD55,CD59,CD6,CD74,CD80,CD81,CD86,CDC123,CDC20,CDC25B,CDC42,CDC6,CDCA7L,CDH13,CDH3,CDK1,CDK13,CDK2,CDK4,CDK6,CDKN1A,CDKN1B,CDON,CFLAR,CGA,CHRD,CHRM1,CHRNB2,CHTOP,CIB1,CLCF1,CLEC11A,CLECL1,CNBP,CNOT6,CNOT6L,CNOT8,CNTF,CNTFR,COL18A1,CORO1A,COX17,CRIP2,CRKL,CSF1,CSF1R,CSF3,CSNK2A1,CSNK2A3,CTF1,CTGF,CTNNB1,CTSH,CTSZ,CUL3,CUL4A,CX3CR1,CXCL10,CXCL5,CXCR2,CYBA,CYR61,DBF4B,DCT,DDR2,DDRGK1,DERL2,DHPS,DHX9,DISC1,DISP3,DLG1,DLL1,DLL4,DLX5,DMRTA2,DNAJA2,DNAJA3,DOT1L,DPPA2,DRD2,DRD3,DYNAP,E2F1,E2F3,EAPP,EBI3,EDN1,EDN2,EDN3,EDNRB,EFNB1,EFNB2,EGF,EGFL7,EGFR,EGR1,EGR3,EGR4,EIF5A2,ELL3,EMP2,EPCAM,EPGN,EPHA1,EPO,ERBB2,ERBB4,EREG,ERN1,ESM1,ESR1,ESRP2,ETS1,ETV5,EYA1,F2,F2R,F3,FABP1,FADD,FAM60A,FAM98A,FAM98B,FASLG,FER,FGF1,FGF10,FGF16,FGF17,FGF18,FGF19,FGF2,FGF20,FGF21,FGF3,FGF4,FGF6,FGF7,FGF9,FGFBP1,FGFR1,FGFR1OP,FGFR2,FGFR3,FGFR4,FLNA,FLT1,FLT3LG,FLT4,FN1,FNTB,FOSL1,FOSL2,FOXE3,FOXF1,FOXG1,FOXM1,FOXP2,FOXP3,FSHB,FTMT,FXN,FZD3,FZD7,FZD9,FZR1,GAB2,GADD45GIP1,GAREM1,GAS6,GATA6,GCNT2,GDF2,GDNF,GFAP,GHRH,GHRHR,GHSR,GJC2,GLI2,GLI3,GLP2R,GLUL,GPAM,GPER1,GPR183,GPR37L1,GREM1,GRK5,HAS2,HAVCR2,HBEGF,HCK,HCLS1,HDAC1,HDAC2,HDAC4,HES1,HES5,HEY2,HGF,HHLA2,HIF1A,HIPK1,HIPK2,HLX,HMGA2,HMGB1,HMGB2,HMGCR,HMGN5,HMOX1,HNRNPU,HPGD,HPN,HPSE,HPSE2,HRAS,HSF1,HSF4,HTR1A,HTR1B,HTR2A,HTR2B,HTRA1,ID1,ID2,ID4,IFNG,IGF1,IGF1R,IGF2,IGFBP2,IHH,IL10,IL12A,IL12B,IL12RB1,IL12RB2,IL13,IL15,IL18,IL1B,IL2,IL21,IL23A,IL23R,IL24,IL31RA,IL34,IL4,IL5,IL6,IL6R,IL6ST,IL7,IL9,INS,INSM1,IQGAP3,IRAK1,IRAK4,IRS1,IRS2,ISL1,ITGA2,ITGAV,ITGB1,JAK2,JAK3,JAML,JCAD,JUN,KCNA5,KDM4C,KDM5B,KIAA1524,KIF20B,KITLG,KLF5,KRAS,KRT6A,LACRT,LAMB1,LBH,LEF1,LEP,LEXM,LGALS9,LHX1,LHX5,LIF,LIFR,LIG4,LILRB2,LIN28A,LRG1,LRP5,LTBP3,LYN,MAB21L1,MAP3K5,MAPK1,MAPK14,MARCKSL1,MAS1,MATK,MCTS1,MDM2,MECP2,MEF2C,MIF,MLXIPL,MMP12,MMP9,MST1R,MTA3,MTOR,MVD,MYB,MYC,MYCN,MYDGF,MYOCD,MZB1,NAMPT,NCCRP1,NCK1,NCK2,NCKAP1L,NDUFS4,NES,NF1,NFATC2,NKX2-5,NKX2-6,NKX3-1,NME1,NME2,NOG,NOTCH1,NOTCH3,NPM1,NPY5R,NQO2,NR4A1,NR4A3,NRG1,NRP1,NRP2,NTF3,NTRK2,NTRK3,NUDT16,OCSTAMP,ODC1,OSM,OSMR,OSR1,PAK1,PAX2,PAX7,PAXBP1,PBX1,PDCD10,PDCD1LG2,PDCD2,PDCD6,PDCL3,PDF,PDGFA,PDGFB,PDGFC,PDGFD,PDGFRB,PELI1,PGGT1B,PHIP,PID1,PIM1,PITX2,PKHD1,PLA2G1B,PLAC8,PLAG1,PML,PNP,POU1F1,POU3F2,POU3F3,PPARD,PPARGC1A,PPP1R16B,PRAMEF1,PRAMEF12,PRAMEF14,PRAMEF19,PRAMEF20,PRC1,PRDX3,PRKAA1,PRKCA,PRKCH,PRKCI,PRKCQ,PRKCZ,PRKD1,PRKD2,PRKDC,PRMT1,PROK1,PROK2,PROX1,PRRX1,PTAFR,PTEN,PTGFR,PTH,PTH1R,PTHLH,PTK2,PTK2B,PTN,PURA,PYCARD,RAB25,RAC2,RARA,RARB,RARG,RASAL3,RBPJ,RBPMS2,REG3A,REG3G,RELA,RETN,RHOG,RICTOR,RIPK2,RNASEH2B,ROGDI,ROMO1,RPL23,RPRD1B,RPS15A,RPS3,RPS4X,RPTOR,RREB1,RTN4,RUNX2,S100A13,S100A6,S100B,S1PR1,S1PR3,SAPCD2,SASH3,SCG2,SCN5A,SCX,SDCBP,SELENOK,SEMA5A,SERPINB3,SERPINB7,SETD1A,SFRP1,SFRP2,SHC1,SHMT2,SHOX2,SIRPG,SIRT1,SIRT6,SIX2,SKP2,SLC25A27,SLC25A33,SLC25A5,SLC35F6,SLC39A10,SMAD4,SMO,SOX10,SOX11,SOX15,SOX4,SOX8,SOX9,SPDYA,SPHK1,SPHK2,SPN,SRPK2,SRSF6,SSBP3,SSR1,ST8SIA1,STAMBP,STAT1,STX3,STX4,STXBP4,SYK,T,TAC1,TAF1,TBC1D8,TBRG4,TBX1,TBX2,TBX20,TBX3,TBX5,TCIRG1,TCL1A,TDGF1,TEK,TERT,TFAP2B,TFRC,TGFB1,TGFB2,TGFBR1,TGFBR2,TGM1,TGM2,THBS1,THBS4,THPO,TIAL1,TIAM1,TICAM1,TIMP1,TIRAP,TLR4,TLR9,TMIGD2,TNC,TNF,TNFAIP3,TNFRSF11A,TNFRSF13C,TNFRSF4,TNFSF12,TNFSF13,TNFSF13B,TNFSF9,TNS3,TP63,TRAF6,TRPC5,TRPM4,TSHR,TSPAN31,TSPO,TSPYL5,TTK,TWIST1,UBE2A,UFL1,UTS2,UTS2R,VASH2,VAV3,VCAM1,VEGFA,VEGFB,VEGFC,VEGFD,VHLL,VIP,VIPR1,VSTM2A,VTCN1,WAPL,WDR77,WNT1,WNT10B,WNT3A,WNT5A,WNT7A,WWTR1,XBP1,XCL1,ZAP70,ZFPM2,ZMIZ1,ZNF16,ZNF335,ZNF580,ZNF703,ZP3,ZP4	TetrapodAncestor	300
GO.Biological.Process	GO:0008285	negative.regulation.of.cell.proliferation	1	1e-300	1e-300	1e-300	1.246166e+0	A4GNT,ABCC8,ABI1,ACVRL1,ADAMTS1,ADAMTS8,ADARB1,ADCYAP1,ADGRB1,ADGRG1,ADIPOQ,ADORA1,ADORA2A,ADORA3,ADRA1A,AGTR2,AIF1,ALOX15B,AMBRA1,APC,APOD,APOE,APOH,APP,AR,ARG1,ARG2,ARID2,ASCL2,ASPH,ATF5,ATM,ATOH8,ATP5A1,ATP8A2,ATPIF1,ATRAID,AXIN2,B4GALT1,B4GALT7,BAK1,BAP1,BAX,BCHE,BCL11B,BCL2,BCL6,BECN1,BMP2,BMP4,BMP5,BMP7,BMPR1B,BMPR2,BNIPL,BRIP1,BTG1,BTG2,BTG3,BTG4,BTK,C18orf54,C1QL4,CAMK2N1,CASK,CASP3,CAV1,CAV2,CCL23,CCL3L3,CCL8,CD109,CD164,CD274,CD300A,CD33,CD9,CDC6,CDC73,CDH13,CDH5,CDK10,CDK6,CDKN1A,CDKN1B,CDKN1C,CDKN2A,CDKN2B,CDKN2C,CDKN2D,CDKN3,CEBPA,CEBPB,CEND1,CER1,CERS2,CGREF1,CGRRF1,CHD5,CHERP,CIB1,CLEC4G,CNN1,CNOT8,COL18A1,COL4A3,COPS8,CPB2,CPEB1,CSF1R,CSK,CSNK2B,CTBP1,CTCF,CTLA4,CTNNA1,CTNNB1,CUL1,CUL2,CUL4A,CUL5,CXCL1,CXCL8,CYP1B1,CYP27B1,DAB2IP,DACH1,DDAH1,DDR1,DEC1,DFNA5,DHCR24,DHRS2,DIS3L2,DLC1,DLG1,DLG3,DLG5,DLL1,DLL4,DNAJA3,DPT,DRD2,DUSP10,E2F1,E2F3,E2F7,EFNB2,EIF2AK2,EMP3,ENPP7,EPHB1,ERBB2,ERBB4,EREG,ETS1,ETV3,F2R,FABP3,FABP6,FABP7,FAM129B,FBLN1,FBXO2,FBXO4,FBXW7,FERMT1,FEZF1,FGF10,FGFBP1,FGFR2,FGFRL1,FKTN,FLCN,FNTB,FOSL1,FOXJ1,FOXO4,FOXP3,FRK,FTH1,FUZ,FZD5,GAL,GAS8,GATA2,GATA3,GDF11,GDF2,GDF5,GGNBP2,GJA1,GLI3,GML,GNRH1,GPC3,GPER1,GPLD1,GPNMB,GREM1,GSTP1,HAVCR2,HDAC4,HES1,HGS,HMOX1,HNF4A,HPGDS,HPN,HRAS,HRG,HSF1,ID2,IDH2,IDO1,IFIT3,IFITM1,IFNG,IFNK,IFNL1,IFNLR1,IFT172,IFT52,IFT57,IFT74,IGFBP5,IGFBP6,IGFBP7,IHH,IL10,IL12A,IL12B,IL15,IL1A,IL1B,IL2,IL20RB,IL24,IL26,IL4,IL6,INCA1,ING2,ING5,INHBA,INPP5D,INSM1,INTU,IRF1,IRF6,ISL1,ITCH,ITGA1,JAK2,JARID2,JUN,KANK2,KARS,KAT2B,KCNK2,KDF1,KDM2B,KIFAP3,KISS1,KLF10,KLF11,KLF13,KLF4,KLF9,KRIT1,LBX1,LDOC1,LGALS9,LIF,LILRB2,LIMS2,LMNA,LRRC32,LST1,LYN,MAD1L1,MAGI2,MAPK11,MARVELD3,MCC,MDM4,MED25,MED31,MEF2C,MEIS1,MEN1,MFN2,MNT,MSTN,MSX1,MSX2,MTBP,MTSS1,MXD4,MYC,MYO16,MYOCD,MYOD1,MYOG,NCK2,NDFIP1,NDRG1,NDRG4,NELL1,NEURL1,NF1,NF2,NFIB,NGFR,NKX3-1,NLRC3,NME1,NOG,NOS3,NOTCH1,NOV,NOX4,NPM1,NPPC,NPR1,NPR3,NR2E3,NRK,NTRK1,NUP62,NUPR1,NUPR2,OGN,OPRM1,OSM,OVOL1,OVOL2,P3H1,P3H2,PAK1,PARP10,PAWR,PBLD,PBRM1,PDCD10,PDCD1LG2,PDCD5,PDE5A,PDPN,PELI1,PEMT,PER2,PEX2,PHB,PHF14,PHOX2B,PIM2,PINX1,PKD2,PKN1,PKP2,PLA2G2D,PLA2G2F,PLG,PLPP1,PLXNB1,PML,PMP22,PODN,POU1F1,PPARD,PPARG,PPARGC1A,PPM1D,PPP2R5C,PRDM1,PRDX4,PRKAR1A,PRKRA,PROX1,PTCH1,PTEN,PTGDR2,PTGES,PTGIR,PTH1R,PTHLH,PTK2B,PTN,PTPN14,PTPRJ,PTPRK,PTPRM,PTPRU,RAF1,RAPGEF1,RAPGEF2,RARA,RARB,RARG,RARRES1,RARRES3,RASSF5,RB1,RBBP4,RBM5,RBP4,RBPJ,RC3H1,RERG,REST,RGCC,RGN,RIPPLY3,RNF10,RNF139,RNF41,ROBO1,ROR2,RPS6KA2,RXFP2,S100A11,SCG2,SCGB1A1,SCIN,SDC4,SERPINE2,SFN,SFRP1,SFRP2,SFRP4,SFRP5,SH3BP4,SIRPG,SIRT2,SIRT6,SIX5,SKAP2,SKI,SLC6A4,SLC9A3R1,SLIT3,SLURP1,SMAD2,SMAD4,SMARCA2,SMARCB1,SMYD2,SNAI2,SOD2,SOX10,SOX11,SOX2,SOX4,SOX7,SOX9,SPEG,SPINT1,SPN,SPRY1,SPRY2,SRF,SRPX,SST,SSTR1,SSTR2,SSTR3,SSTR4,SSTR5,ST18,STAT1,STK4,STRAP,STRN,SULT2B1,SYNJ2BP,TAX1BP3,TBRG1,TBX5,TENM1,TERT,TES,TESC,TFAP2A,TFAP2B,TFF1,TGFB1,TGFB1I1,TGFB2,TGFBR1,TGFBR2,THAP12,THBS1,TIMP2,TINF2,TLR2,TMEM115,TMEM127,TMEM131L,TMIGD3,TNF,TNFAIP3,TNFRSF13B,TNFRSF14,TNFRSF21,TNFRSF8,TNFRSF9,TNMD,TNN,TNS2,TP53,TP53I11,TP53INP1,TP73,TRIB1,TRIM24,TRIM32,TSC2,TSG101,TSPAN32,TSPO,UMOD,VASH1,VDR,VEGFC,VIPR2,VSIG4,VTCN1,WARS,WDR77,WFDC1,WNK2,WNT10B,WNT11,WNT5A,WNT9A,XCL1,XDH,ZBTB16,ZBTB17,ZBTB49,ZBTB7C,ZEB1	TetrapodAncestor	300
GO.Biological.Process	GO:0009887	animal.organ.morphogenesis	1	1e-300	1e-300	1e-300	1.197337e+0	ABLIM1,ABR,ACP4,ACP5,ACTA2,ACTG2,ACVR2B,ACVRL1,ADAM15,ADAMTS1,ADAMTS16,ADAMTS5,ADARB1,ADGRG6,AES,AGTPBP1,AGTR2,AHI1,ALDH1A3,ALPL,ALX1,ALX4,AMELX,ANKRD1,APLP1,AQP1,AQP3,AQP5,AQP6,AR,AREG,ARG1,ARID1A,ARID2,ARID5B,ARL13B,ARL6,ASH1L,ASXL1,ATOH1,ATP6V1B1,ATP8A2,AXIN2,BAK1,BARX2,BAX,BBS4,BBS7,BCAR3,BCL11B,BCL2,BCL2L11,BCOR,BCR,BGLAP,BHLHE41,BMP1,BMP10,BMP2,BMP4,BMP5,BMP6,BMP7,BMPR1A,BMPR1B,BMPR2,BRAF,BSG,BSX,BTRC,C2CD3,CA2,CABP4,CALB1,CAPN1,CARM1,CAV1,CAV3,CCDC103,CCDC40,CCL11,CCL2,CCM2L,CDC42,CDH2,CDON,CDX1,CEBPB,CELSR1,CEMP1,CER1,CHD7,CHRNA10,CHRNA9,CHST11,CITED1,CITED2,CLDN5,CLIC5,CNNM4,CNTF,COL10A1,COL11A1,COL13A1,COL18A1,COL1A1,COL1A2,COL27A1,COL2A1,COL3A1,COL5A1,COL5A2,COL8A1,COL8A2,CRB1,CRB2,CRIP1,CRKL,CRX,CSF1,CSF1R,CSF3R,CSGALNACT1,CSRNP1,CTGF,CTNNA1,CTNNA2,CTNNB1,CTSH,CTSZ,CUL1,CUL3,CYP26B1,CYR61,DCANP1,DCHS1,DCN,DDR1,DGCR2,DHRS3,DIO3,DLC1,DLG1,DLG5,DLL1,DLL4,DLX3,DLX5,DNAAF1,DSCAM,DSCAML1,DSP,DUOX2,DVL1,E2F4,E2F5,EDA,EDAR,EDN1,EFEMP1,EFNA1,EFNB2,EGF,EGFR,EGLN1,EIF4A3,ELF3,ELN,EMX1,ENG,EP300,EPHA2,EPHB1,EPHB2,EPHB4,EREG,ERG,ERRFI1,ESR1,ESRP2,ETV7,EVL,EXOC4,EYA1,FAM20A,FAM20C,FANCC,FASLG,FAT4,FBN2,FEM1B,FGD1,FGF1,FGF10,FGF16,FGF18,FGF2,FGF4,FGF6,FGF7,FGF9,FGFR1,FGFR2,FGFR3,FGFRL1,FHL2,FJX1,FKBP1A,FLI1,FLRT2,FLVCR1,FMN1,FOXA1,FOXC1,FOXC2,FOXE1,FOXE3,FOXF1,FOXF2,FOXG1,FOXH1,FOXI1,FOXJ1,FOXL1,FOXN1,FOXN3,FOXN4,FOXO1,FRAS1,FREM1,FRS2,FUZ,FZD1,FZD2,FZD3,FZD5,FZD6,GAA,GATA2,GATA3,GATA4,GATA6,GBA,GBX2,GCNT3,GCNT4,GDF11,GDNF,GLG1,GLI2,GLI3,GMNN,GNAS,GNGT1,GPC3,GREM1,GRHL2,GRHL3,GSC,GSK3A,GZF1,HAND1,HAND2,HAS2,HCCS,HCN1,HDAC1,HDAC2,HEG1,HES1,HES5,HESX1,HEY1,HEY2,HEYL,HHEX,HIF1A,HIPK1,HIPK2,HLX,HMGN1,HNF1B,HOXA1,HOXC13,HPN,HRAS,HTR2B,HTRA1,ID1,ID2,ID3,ID4,IFITM5,IFT140,IFT172,IFT52,IFT57,IGFBP5,IHH,IL6,IL7,IMPAD1,INHBA,INSIG2,ISL1,ITGA2,ITGA8,ITGAX,ITGB4,JAG1,JAG2,JUN,KCNQ4,KDM2B,KDM5B,KDM6A,KIF26B,KLHL3,KRAS,KRT13,LAMA5,LAMB1,LBX1,LEF1,LEFTY1,LEMD2,LFNG,LGR4,LHFPL5,LHX1,LHX4,LHX8,LIF,LRIG1,LRIG3,LRP4,LRP5,LRP6,LRRK2,LY6H,MAFB,MAN2A1,MAPK1,MAPK14,MAPK3,MATN1,MDFI,MDM2,MEF2C,MEF2D,MEGF8,MEIS1,MESP1,MESP2,MFAP2,MFN2,MFRP,MGP,MIB1,MKKS,MMP13,MMP14,MMP16,MMP20,MSN,MSX1,MSX2,MTHFD1,MTHFD1L,MTOR,MYBPC3,MYC,MYCN,MYF6,MYH6,MYH7,MYL3,MYLK,MYLK2,NAB2,NDRG4,NDST1,NECTIN1,NECTIN3,NEK8,NEUROD1,NEUROG1,NF1,NF2,NFIB,NFIC,NIPBL,NKX2-3,NKX2-5,NKX3-1,NKX3-2,NKX6-1,NLE1,NOG,NOTCH1,NOTCH2,NOTO,NPHP3,NPPC,NPY1R,NPY2R,NPY5R,NR2E3,NR4A3,NR5A2,NRG1,NRG3,NRL,NRP1,NRP2,NSD2,NTF4,NTRK2,OLFM1,OLFM3,OSR1,OTOR,OTX1,OVOL2,P2RX7,PAFAH1B1,PALB2,PAM,PAPPA2,PAX2,PAX3,PAX4,PAX5,PAX7,PAX8,PAX9,PBX1,PCGF2,PDGFA,PDGFC,PDGFRB,PDZD7,PERP,PEX7,PGR,PHACTR4,PHLDA2,PHOSPHO1,PITX2,PKD1,PKD2,PKP2,PLAG1,PLEKHA1,PLXNA1,PLXND1,PML,POC1A,POLB,POU3F4,POU4F1,POU4F3,PPARA,PPARGC1B,PPP1R13L,PRDM1,PRKCI,PRKRA,PRKX,PROM1,PROP1,PROX1,PRRX1,PSEN1,PTCD2,PTCH1,PTEN,PTF1A,PTK2,PTK7,PTN,PTPRM,RAB23,RAB33B,RARA,RARB,RARG,RBP4,RBPJ,RBPMS2,RDH10,RDH13,RELA,RFLNB,RFNG,RING1,RIPPLY1,RIPPLY2,ROGDI,ROM1,ROR2,RORB,RP1,RPE65,RPGRIP1,RPL38,RPS6KA1,RS1,RSPO2,RTN4,RUNX2,RXRA,RYR1,RYR2,S1PR1,SATB2,SCN5A,SCRIB,SCX,SDK1,SDK2,SEC24B,SEMA3A,SEMA3C,SEMA6A,SERP1,SERPINB5,SERPINH1,SETD2,SETDB2,SFRP1,SFRP2,SFRP4,SFTPB,SGPL1,SHOX2,SHROOM2,SIRT6,SIX2,SKI,SLC24A4,SLC34A1,SLC39A3,SLC40A1,SLC6A4,SLC9A3R1,SLIT1,SLIT3,SLITRK6,SMAD2,SMAD4,SMAD7,SMARCC1,SMO,SNAI1,SNAI2,SOBP,SOD1,SOS1,SOSTDC1,SOX1,SOX11,SOX17,SOX18,SOX4,SOX8,SOX9,SPRY1,SPRY2,SRC,SRF,SSUH2,STAT6,STC1,STIL,STIM1,STRA6,STRC,SUFU,SYCP2,SYK,T,TAB1,TACSTD2,TBC1D20,TBX1,TBX15,TBX2,TBX20,TBX3,TBX5,TCF15,TCF21,TDRD7,TEAD2,TEK,TENM3,TFAP2A,TFAP2B,TGFB1,TGFB2,TGFBR1,TGFBR2,TGM2,TH,THBS3,THRA,THRB,THY1,TIFAB,TIPARP,TLE1,TLE2,TLE3,TMED2,TMEM100,TMEM176B,TMIE,TNC,TNF,TNFSF11,TNNC1,TNNI3,TNNT2,TOPORS,TP63,TRAF6,TREH,TRIP11,TRPM1,TSKU,TSPAN12,TTN,TUFT1,TULP1,TULP3,TWIST1,UCHL5,USH1C,USH1G,VANGL2,VAX2,VDR,VEGFA,VEGFC,VHLL,VSX1,WDR60,WDR72,WNK4,WNT1,WNT10A,WNT10B,WNT11,WNT16,WNT3A,WNT4,WNT5A,WNT6,WNT7A,WNT7B,WNT9A,WNT9B,WWOX,WWTR1,YY1,ZEB1,ZFAND5,ZFPM1,ZFPM2,ZIC1,ZIC3,ZMIZ1,ZNF335	TetrapodAncestor	300
GO.Biological.Process	GO:0022407	regulation.of.cell-cell.adhesion	1	1e-300	1e-300	1e-300	1.403418e+0	ABAT,ABL1,ADA,ADAM8,ADAMTS18,ADIPOQ,ADORA2A,AGER,AIF1,ALOX15,ANK3,ANXA1,AP3D1,APOA1,ARG1,ARG2,ASS1,B4GALNT2,BAD,BCL10,BCL6,BMP4,BMP7,BRAF,BTLA,C1QTNF1,CAMK4,CARD11,CASP3,CAV1,CBFB,CCDC88B,CCL19,CCL2,CCL21,CCL28,CCL5,CCM2L,CCR2,CCR7,CD1D,CD2,CD209,CD24,CD247,CD27,CD274,CD276,CD28,CD300A,CD3D,CD3E,CD3G,CD44,CD46,CD47,CD5,CD55,CD59,CD6,CD74,CD80,CD83,CD86,CD9,CDC42,CDH1,CEBPB,CELSR2,CITED2,CLC,CLEC4G,CLECL1,CORO1A,CR1,CSK,CTLA4,CTNNB1,CXCL13,CYP26B1,DHPS,DLG1,DLG5,DMTN,DNAJA3,DOCK8,DROSHA,DTX1,DUSP10,DUSP22,DUSP3,EBI3,EFNA5,EFNB1,EFNB2,EFNB3,EPB41L5,EPCAM,EPHA7,EPHB3,EPO,ERBB2,ETS1,FADD,FAM49B,FANCA,FERMT3,FGG,FLOT1,FLOT2,FOXA1,FOXA2,FOXJ1,FOXN1,FOXP3,FSTL3,GATA3,GCNT2,GLI2,GLI3,GNRH1,GPAM,GPNMB,GRAP2,GRB2,GSN,HAS2,HAVCR2,HES1,HHLA2,HLX,HMGB1,HSPH1,ICOS,IDO1,IFNA2,IFNB1,IFNG,IFNL1,IFNL2,IFNL3,IGF1,IGF2,IGFBP2,IHH,IL10,IL12A,IL12B,IL12RB1,IL15,IL18,IL1B,IL1RL2,IL1RN,IL2,IL20RB,IL21,IL23A,IL23R,IL27,IL36B,IL4,IL6,IL6ST,IL7,IL7R,IRF1,IRF4,ITCH,ITGA4,ITPKB,JAK2,JAK3,KIF26B,KIRREL1,KLF4,KLRK1,LAT,LAX1,LCK,LEF1,LEP,LGALS1,LGALS3,LGALS9,LILRB2,LILRB4,LOXL3,LRRC32,LYN,MAD1L1,MAD2L2,MALT1,MAP3K14,MAP3K7,MAP3K8,METTL3,MINK1,MYADM,MYB,MYO10,NCK1,NCK2,NCKAP1L,NDFIP1,NF2,NFATC2,NFKBID,NPHS1,NR4A3,PAG1,PAK1,PAK2,PAK3,PAWR,PDCD1,PDCD1LG2,PDE5A,PDPK1,PDPN,PELI1,PIEZO1,PIK3CA,PIK3R1,PIK3R6,PLA2G2D,PLA2G2F,PLG,PLPP3,PNP,PODXL,PPARA,PRDM1,PRELID1,PRKAR1A,PRKCA,PRKCD,PRKCQ,PRKCZ,PRKG1,PTAFR,PTK2,PTPN11,PTPN22,PYCARD,RAC1,RAC2,RAG1,RARA,RASAL3,RASGRP1,RC3H1,RDX,RGCC,RIPK2,RIPK3,RIPOR2,RNASE10,RPS3,RUNX1,SART1,SASH3,SCGB1A1,SDC4,SELENOK,SERPINE2,SHB,SIRPG,SIT1,SLC46A2,SMAD7,SOCS1,SOCS5,SOCS6,SOD1,SOS1,SOX13,SOX2,SPINK5,SPN,SRC,SYK,TARM1,TESPA1,TFRC,TGFB1,TGFBR2,THY1,TIGIT,TMEM131L,TMIGD2,TNF,TNFAIP8L2,TNFRSF13C,TNFRSF14,TNFRSF18,TNFRSF21,TNFSF11,TNFSF13B,TNFSF14,TNFSF18,TNFSF9,TNR,TRAF2,TRAF6,UBASH3B,VAV1,VCAM1,VNN1,VPS33B,VSIG4,VTCN1,WNT1,WNT3A,WNT4,WNT5A,XBP1,XCL1,YES1,YTHDF2,ZAP70,ZBTB1,ZBTB16,ZBTB7B,ZC3H8,ZEB1,ZMIZ1,ZNF683,ZNF703,ZP3,ZP4	TetrapodAncestor	300
GO.Biological.Process	GO:0022603	regulation.of.anatomical.structure.morphogenesis	1	1e-300	1e-300	1e-300	1.225392e+0	ABCC8,ABL1,ABR,ACTN4,ACTR2,ACVRL1,ADA,ADAM9,ADAMTS12,ADAMTS9,ADGRA2,ADGRB1,ADGRB2,ADGRB3,ADIPOQ,ADM2,ADNP,AGGF1,AGO4,AGT,AGTR2,AHI1,AJAP1,AKAP13,ALDOA,AMELX,AMOT,ANAPC2,ANGPT2,ANGPT4,ANGPTL4,ANKRD27,ANKRD6,ANXA1,ANXA3,AP1AR,AP2A1,AP2A2,AP2B1,AP2M1,AP2S1,APELA,APLNR,APOA1,APOE,APOH,AQP1,AR,ARAP1,ARAP3,ARC,ARHGAP15,ARHGAP18,ARHGAP35,ARHGAP4,ARHGAP44,ARHGDIA,ARHGEF19,ARHGEF7,ARPC2,ARPIN,ARRB2,ASPN,ATP10A,B4GALT1,BAMBI,BASP1,BAX,BCL11A,BCL2,BCL6,BCL9L,BCOR,BCR,BDNF,BMP10,BMP2,BMP4,BMP7,BMPR1A,BMPR2,BNIP3,BRAF,BRCA1,BRWD1,BRWD3,BTG1,BVES,C15orf62,C1QBP,C21orf2,C3,C3AR1,C4orf26,C5,C6,CALR,CAMK1,CAMK2B,CAMSAP1,CAPRIN1,CAPRIN2,CAPZB,CARM1,CARMIL1,CAV3,CCBE1,CCL11,CCL13,CCL2,CCL3,CCL7,CCR2,CCR3,CD34,CD36,CD40,CD44,CD53,CDC42,CDC42EP1,CDC42EP2,CDC42EP3,CDC42EP4,CDC42EP5,CDC42SE1,CDH4,CDK5,CDK5R1,CDKL5,CDX1,CELSR1,CELSR2,CFDP1,CFL1,CFLAR,CHAD,CHI3L1,CHRNA3,CHRNB2,CIB1,CITED1,CITED2,CLASP1,CLASP2,CLTC,CNMD,CNTF,CNTN2,COL4A3,COL5A1,COL5A2,CORO1A,CORO1B,CPB2,CPNE5,CPNE6,CRABP2,CRB2,CRK,CRKL,CSF1,CSF1R,CSNK1A1,CSNK1D,CSNK1E,CSNK1G1,CSNK1G2,CSNK1G3,CTNNB1,CTSH,CTTN,CUL7,CUX1,CUX2,CX3CL1,CX3CR1,CXCL10,CXCL13,CXCL8,CXCL9,CYBB,CYFIP1,CYP1B1,CYSLTR2,DAAM1,DAB1,DAB2,DAB2IP,DACT1,DAPK3,DCC,DCN,DDAH1,DDHD1,DDHD2,DHODH,DIAPH1,DISC1,DKK1,DKK4,DLC1,DLG1,DLL1,DLL4,DMP1,DMTN,DNM1L,DNM2,DOCK5,DPYSL2,DRAXIN,DSCAM,DUSP6,DVL1,DVL3,ECSCR,EDN1,EEF2K,EFNA1,EFNA3,EFNA5,EFNB2,EFNB3,EGLN1,EHD1,EHD2,EMP2,ENG,ENPP2,ENSG00000260272,EPB41,EPB41L3,EPHA1,EPHA2,EPHA4,EPHA7,EPHB2,EPHB3,EPS8,ERAP1,ERBB2,ERG,ESR1,ETS1,ETV5,EYA1,EZR,F2,F3,FAM129B,FASLG,FBLN1,FBXO31,FBXW7,FBXW8,FERMT2,FES,FGD1,FGD2,FGD3,FGD4,FGD5,FGF1,FGF10,FGF13,FGF2,FGF7,FGFR1,FGFR2,FGG,FGR,FIS1,FITM2,FLNA,FLOT1,FLT1,FLT3LG,FLT4,FMNL1,FMNL2,FMNL3,FN1,FOXA2,FOXC1,FOXC2,FOXJ1,FOXO4,FOXP2,FRS2,FSTL4,FUZ,FZD1,FZD2,FZD3,FZD4,FZD5,FZD6,FZD7,GAB1,GAL,GAS2,GATA2,GATA3,GATA4,GATA6,GDF2,GDI1,GDNF,GHSR,GNA12,GNA13,GOLGA4,GPC3,GPC4,GPC6,GPNMB,GPR4,GREM1,GRHL3,GRIN1,GTF2I,HAND2,HAS2,HCK,HDAC5,HDAC7,HDAC9,HES1,HES7,HEY1,HEY2,HGF,HHEX,HIF1A,HIF1AN,HIPK1,HIPK2,HMGA2,HMGB1,HMOX1,HNF1B,HNF4A,HPN,HRG,HSPB1,HSPB6,HSPG2,ID1,IFNG,IFRD1,IL10,IL17F,IL1A,IL1B,IL1RAPL1,IL1RN,IL4,IL6,INF2,ISL1,ISLR2,IST1,ITGA5,ITGA7,ITGB2,ITPKA,ITSN2,JCAD,KALRN,KANK1,KEL,KIF13B,KLF4,KRIT1,KRT1,L1CAM,LARP4,LEP,LFNG,LGR4,LHX1,LIF,LIMD1,LIMK1,LIMS2,LINGO1,LPAR1,LPAR3,LRG1,LRP4,LRP8,LRRC4C,LRRK2,LST1,LZTS1,LZTS3,MACF1,MAG,MAGI2,MAP1B,MAP2,MAPK14,MAPT,MARCH5,MARK2,MCF2,MEF2C,MEGF8,MELTF,MEOX2,MESP1,METRN,MFF,MIEF1,MIEF2,MKLN1,MKS1,MLLT3,MMP20,MMRN2,MSN,MSX1,MTDH,MTOR,MUL1,MYADM,MYC,MYDGF,MYF6,MYH10,MYH14,MYH9,MYL12B,MYLK3,MYO10,MYO19,MYOD1,MYOG,NDEL1,NEDD4L,NEFL,NET1,NEUROG3,NF1,NFATC2,NFATC4,NFIB,NGEF,NGF,NGFR,NKX6-1,NLGN1,NLGN3,NOG,NOS3,NOTCH1,NPHP3,NPR1,NRG1,NRP1,NTRK2,NTRK3,NUMB,OCSTAMP,OLFM1,OLFM4,OMA1,OMG,OPA1,OSR1,OSTN,OTX2,PAFAH1B1,PAK1,PAK3,PALM,PALM2,PALM2-AKAP2,PALMD,PARD6A,PARVB,PAX2,PAX8,PAX9,PDCD10,PDCD6,PDCL3,PDGFA,PDLIM5,PDPN,PDZD8,PF4,PFN1,PGK1,PHIP,PHLDB1,PHLDB2,PID1,PIK3R6,PIM1,PINK1,PKN1,PLAA,PLCG1,PLD6,PLEKHO1,PLXNA1,PLXNA2,PLXNA3,PLXNA4,PLXNB1,PLXNB2,PLXNC1,PLXND1,PML,POGLUT1,POR,POU3F2,PPARG,PPARGC1A,PPP1R16B,PPP3CA,PQBP1,PREX1,PRICKLE1,PRKCA,PRKCB,PRKD1,PRKD2,PRKN,PROK1,PROK2,PROX1,PRPF40A,PSEN1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTEN,PTGIS,PTK2,PTK2B,PTK7,PTN,PTPRD,PTPRM,PTPRO,PTPRS,RAB21,RAC1,RAC3,RAMP2,RAP1A,RAP2A,RAPGEF2,RAPGEF3,RASA1,RASAL1,RBPJ,RC3H1,RCC2,RDX,RELN,RET,RGCC,RHOJ,RHOQ,RHOU,RIMS1,RIPOR2,RLN2,RND2,RNF207,RNF6,RNH1,ROBO1,ROBO2,ROCK2,ROR2,RPS27A,RRAS,RREB1,RSPO2,RSPO3,RTN4,RTN4R,RUFY3,RUNX1,RUNX2,RXRA,RYK,S100A10,S100A13,S100B,SAPCD2,SARM1,SARS,SASH1,SCGB3A1,SCX,SDC2,SEC24B,SEMA3A,SEMA3C,SEMA3E,SEMA3G,SEMA4A,SEMA4D,SEMA5A,SEMA7A,SEPT7,SFRP1,SFRP2,SFRP5,SH3KBP1,SHOX2,SHROOM3,SIPA1L1,SIRT1,SIRT6,SIX2,SKIL,SLC26A5,SLC9A3R1,SLIT2,SLITRK1,SMAD4,SMO,SMURF1,SMURF2,SNAI2,SOX17,SOX8,SOX9,SP100,SPHK1,SPINK5,SPP1,SPRED1,SPRY1,SRC,SRCIN1,SRF,SRPX2,SRSF6,SSH2,SSH3,STARD13,STAT1,STAT2,STIM1,STRIP1,STRIP2,SULF2,SYNE3,SYNGAP1,SYNJ2BP,SYT1,SYT17,SYT2,SYT4,TACSTD2,TAOK2,TBCCD1,TBX1,TBX18,TBX2,TBX5,TBXA2R,TEK,TENM4,TERT,TFAP2A,TGFB1,TGFB2,TGFBR1,TGFBR2,TGIF2,THBS1,THBS2,THBS4,THY1,TIAM1,TIE1,TLX2,TMBIM1,TMEM100,TMEM135,TMEM2,TMIGD2,TNF,TNFAIP3,TNFRSF11B,TNFRSF12A,TNFRSF13C,TNFSF12,TNFSF13B,TNFSF14,TNIK,TNMD,TNR,TRAK1,TRAK2,TRIOBP,TRPC5,TRPC6,TSPAN12,TTBK2,TTL,TUBB2B,TWF2,TWIST1,UBC,UBE3A,ULK2,UNC13A,UST,UTS2,UTS2R,VANGL1,VANGL2,VASH1,VASH2,VAT1,VDR,VEGFA,VEGFB,VEGFC,VEGFD,VIL1,VPS35,VRK1,VRK2,VRK3,WARS,WASHC2C,WDR1,WDR36,WNT1,WNT10A,WNT11,WNT3,WNT3A,WNT4,WNT5A,WNT6,WNT7A,WNT9B,XBP1,XDH,XK,YWHAH,ZC3H12A,ZFYVE27,ZMYM2,ZMYM4,ZMYM5,ZMYM6,ZNF135,ZNRF3	TetrapodAncestor	300
GO.Biological.Process	GO:0030097	hemopoiesis	1	1e-300	1e-300	1e-300	1.313746e+0	ABI1,ABL1,ACE,ACIN1,ACTN1,ADA,ADAR,ADD1,ADGRG3,AGPAT5,AICDA,ANGPT1,ANLN,ANXA1,APP,ARHGEF7,ARID4A,ARMC6,ASH2L,ASXL1,ATG5,ATM,ATP11C,ATPIF1,AXL,AZI2,BABAM1,BAK1,BATF2,BATF3,BAX,BCL11B,BCL2,BCL3,BCL6,BCR,BLNK,BMI1,BMP4,BMX,BRAF,BTK,CAMK4,CARD11,CASP3,CASP8,CASP9,CBFB,CCL19,CCR6,CCR7,CCR9,CD109,CD164,CD1D,CD28,CD34,CD3D,CD3E,CD74,CD79B,CD86,CD8A,CDC42,CDK13,CDK6,CDKN1C,CDKN2B,CEBPA,CEBPD,CEBPE,CEBPG,CHD2,CHD7,CIAPIN1,CIB1,CLCF1,CLEC1B,CLEC4D,CLEC4E,CMTM7,COL24A1,CR2,CRIP2,CSF1,CSF1R,CSF3,CTNNB1,CUL4A,DACT2,DCAF1,DCLRE1C,DHRS2,DHTKD1,DLL1,DLL4,DMTN,DNAJA3,DNASE2,DOCK10,DOCK11,DOCK2,DYRK3,EEF2,EFNA4,EGR1,EML1,EOMES,EP300,EPAS1,EPHA2,EPO,ERCC1,ERCC2,ESCO2,ETV6,F2RL1,FADD,FAM20C,FAM210B,FAS,FCER1G,FGFR2,FLCN,FLI1,FLT3LG,FLVCR1,FOXN1,FOXP3,FST,FSTL3,FUT10,FUT7,FZD5,FZD7,FZD8,FZD9,G6PD,GAB2,GAS6,GATA2,GATA3,GLI3,GLO1,GLRX5,GON4L,GPC3,GPR18,GPR183,HBZ,HCLS1,HDAC4,HDAC5,HDAC9,HEATR9,HHEX,HIF1A,HIPK1,HIPK2,HMGB1,HNF1A,HSPA9,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNB1,IFNE,IFNG,IFNK,IFNW1,IKZF1,IL10,IL12B,IL15,IL18R1,IL2,IL31RA,IL4,IL6,IL7,IL7R,INHA,INHBA,IRF1,IRF4,IRF8,ITFG2,ITGA4,ITGB1,ITK,ITM2A,ITPKB,JAG1,JAG2,JAGN1,JAK2,JAK3,JAM3,JMJD6,JUN,JUNB,KAT6A,KAT8,KCNAB2,KDELR1,KIRREL3,KITLG,KLF1,KLF2,KLF4,KLF6,KMT2E,KRT75,L3MBTL1,L3MBTL3,LCK,LEF1,LEP,LEPR,LFNG,LGALS1,LIG4,LRRC8A,LTBR,LY6D,LYL1,LYN,MAEA,MAFB,MALT1,MAPK14,MB,MECOM,MEF2C,MEIS1,MELK,MEOX1,MERTK,MFAP5,MFNG,MIXL1,MKNK2,MLF1,MMP9,MSH2,MYH9,MYO1E,NARFL,NBEAL2,NCKAP1L,NCOA6,NFAM1,NHEJ1,NKX2-3,NKX2-5,NOTCH2,NOTCH4,NTRK1,OCSTAMP,ONECUT1,OSTM1,PAFAH1B1,PAPD4,PARP1,PATZ1,PBX1,PDE1B,PGM3,PICALM,PIK3CD,PIK3R1,PIP4K2A,PIR,PKNOX1,PLA2G2D,PLCG2,PLCL2,PLEK,PML,POLM,POU1F1,POU2F2,PPARG,PPP3CB,PRDX3,PREX1,PRKDC,PRKX,PSEN1,PSMB11,PTBP3,PTGER4,PTK2B,PTPN11,PTPN22,PTPRZ1,RAG1,RAG2,RASGRP4,RB1,RBM47,RBPJ,RC3H1,RC3H2,RELB,REST,RHAG,RIPK3,ROGDI,RORC,RPS14,RPS6,RRAS,RSAD2,RTKN2,RUNX1,RUNX2,SATB1,SEMA4A,SERPINB12,SFRP1,SFRP2,SFXN1,SGPL1,SH2B3,SH3PXD2A,SHB,SIPA1L3,SIRT1,SLAMF6,SLC25A38,SLC7A6OS,SLC8A3,SMAD5,SMPD3,SNRK,SNX10,SOX4,SP7,SPI1,SPN,SRC,SRF,SSBP3,STAT6,STK4,STON2,SYK,TAL1,TAZ,TCF3,TEK,TESC,TET2,TFRC,TGFB1,TGFB2,TGFBR2,THEMIS,THOC5,THPO,THRA,TIPARP,TIRAP,TLR2,TMEM91,TMOD3,TNF,TNFRSF11A,TNFRSF13B,TNFSF11,TNFSF8,TOP2A,TPD52,TPO,TRAF6,TREM2,TRPM2,TSPAN2,TTC7A,TYRO3,VAV1,VCAM1,VEGFA,VPS33B,WASF2,WDR1,WDR7,WDR78,WNT1,WNT10B,WNT3A,WNT4,WNT5A,XRCC5,ZAP70,ZBTB1,ZBTB16,ZBTB24,ZFAT,ZFP36L1,ZFP36L2,ZFPM1,ZNF160,ZNF385A,ZNF683,ZNF784	TetrapodAncestor	300
GO.Biological.Process	GO:0030155	regulation.of.cell.adhesion	1	1e-300	1e-300	1e-300	1.330295e+0	ABAT,ABI3BP,ABL1,ABL2,ACER2,ACTN4,ACVRL1,ADA,ADAM15,ADAM22,ADAM8,ADAM9,ADAMDEC1,ADAMTS18,ADGRG1,ADIPOQ,ADORA2A,AGER,AGR2,AIF1,AJAP1,ALOX15,ANGPT1,ANGPT2,ANK3,ANXA1,AP1AR,AP3D1,APOA1,APOD,ARG1,ARG2,ARHGAP6,ARHGDIA,ARHGDIB,ARHGEF7,ARL2,ARPC2,ASS1,ATXN3,B4GALNT2,BAD,BAG4,BCAS3,BCL10,BCL2,BCL6,BMP2,BMP4,BMP7,BRAF,BST1,BTLA,C1QBP,C1QTNF1,CALR,CAMK4,CAMSAP3,CARD11,CARMIL1,CASK,CASP3,CAV1,CBFB,CBLL1,CCDC80,CCDC88B,CCL19,CCL2,CCL21,CCL28,CCL5,CCM2L,CCR2,CCR7,CD164,CD1D,CD2,CD209,CD24,CD247,CD27,CD274,CD276,CD28,CD300A,CD36,CD3D,CD3E,CD3G,CD44,CD46,CD47,CD5,CD55,CD59,CD6,CD74,CD80,CD83,CD86,CD9,CDC42,CDH1,CDH13,CDK6,CDKN2A,CEBPB,CELSR2,CHRD,CIB1,CITED2,CLASP1,CLASP2,CLC,CLEC4G,CLECL1,COL16A1,COL1A1,COL26A1,COL8A1,CORO1A,CR1,CRK,CRKL,CSF1,CSK,CTLA4,CTNNB1,CX3CL1,CXCL13,CXCL8,CYP1B1,CYP26B1,CYR61,CYTH1,CYTH3,DAB1,DACT2,DAPK3,DDR1,DHPS,DISC1,DLC1,DLG1,DLG5,DLL1,DMP1,DMTN,DNAJA3,DNM2,DOCK5,DOCK8,DROSHA,DSCAM,DTX1,DUSP10,DUSP22,DUSP26,DUSP3,EBI3,ECM2,EDIL3,EFNA1,EFNA5,EFNB1,EFNB2,EFNB3,EGFLAM,EMP2,EPB41L4B,EPB41L5,EPCAM,EPHA1,EPHA2,EPHA3,EPHA7,EPHA8,EPHB3,EPO,ERBB2,ETS1,FADD,FAF1,FAM49B,FANCA,FBLN1,FERMT1,FERMT3,FES,FGG,FLCN,FLNA,FLOT1,FLOT2,FMN1,FN1,FOXA1,FOXA2,FOXC2,FOXF1,FOXJ1,FOXN1,FOXP3,FRMD5,FSTL3,FXYD5,FZD4,FZD7,GATA3,GCNT2,GLI2,GLI3,GNRH1,GPAM,GPM6B,GPNMB,GRAP2,GRB2,GREM1,GSN,HAS2,HAVCR2,HES1,HHLA2,HLX,HMGB1,HRG,HSD17B12,HSPH1,IBSP,ICOS,IDO1,IFNA2,IFNB1,IFNG,IFNL1,IFNL2,IFNL3,IFT74,IGF1,IGF2,IGFBP2,IHH,IL10,IL12A,IL12B,IL12RB1,IL15,IL18,IL1B,IL1RL2,IL1RN,IL2,IL20RB,IL21,IL23A,IL23R,IL27,IL36B,IL4,IL6,IL6ST,IL7,IL7R,IQGAP1,IRF1,IRF4,ITCH,ITGA2,ITGA3,ITGA4,ITGA5,ITGAV,ITPKB,JAG2,JAK2,JAK3,JAM2,KANK1,KIF26B,KIFAP3,KIRREL1,KLF4,KLRK1,KNG1,LAMA1,LAMA2,LAMA3,LAMA4,LAMA5,LAT,LAX1,LCK,LEF1,LEP,LGALS1,LGALS3,LGALS9,LILRB2,LILRB4,LMO7,LOXL3,LPXN,LRRC32,LYN,MACF1,MAD1L1,MAD2L2,MALT1,MAP3K14,MAP3K7,MAP3K8,MELTF,MEN1,METTL3,MIA3,MINK1,MMP14,MUC1,MYADM,MYB,MYO10,NCK1,NCK2,NCKAP1L,NDFIP1,NDNF,NET1,NF1,NF2,NFATC2,NFKBID,NINJ1,NOTCH1,NPHS1,NPY2R,NR4A3,NRP1,NUAK1,OLFM4,ONECUT1,PAG1,PAK1,PAK2,PAK3,PAWR,PDCD1,PDCD1LG2,PDE5A,PDPK1,PDPN,PELI1,PHLDB2,PIEZO1,PIK3CA,PIK3CG,PIK3R1,PIK3R6,PKD1,PLA2G2D,PLA2G2F,PLAU,PLEKHA2,PLET1,PLG,PLPP3,PLXNB1,PLXNB2,PLXNC1,PLXND1,PML,PNP,PODXL,PPARA,PPM1F,PPP1CB,PPP1R12A,PRDM1,PRELID1,PREX1,PRKAR1A,PRKCA,PRKCD,PRKCE,PRKCQ,PRKCZ,PRKD2,PRKG1,PRKX,PRSS2,PTAFR,PTEN,PTK2,PTK2B,PTN,PTPN11,PTPN22,PTPN23,PTPRJ,PTPRO,PYCARD,RAC1,RAC2,RAC3,RAG1,RARA,RASA1,RASAL3,RASGRP1,RC3H1,RCC2,RDX,RELL2,RET,RGCC,RHOD,RIPK2,RIPK3,RIPOR2,RNASE10,RND1,ROCK2,RPS3,RREB1,RSU1,RUNX1,S100A10,S1PR1,SAA1,SART1,SASH3,SCGB1A1,SDC4,SELENOK,SEMA3E,SEMA4D,SEMA5A,SERPINE2,SERPINI1,SFRP1,SFRP2,SHB,SIPA1,SIRPG,SIT1,SLC46A2,SLC9A1,SMAD7,SMOC2,SNAI2,SOCS1,SOCS5,SOCS6,SOD1,SOS1,SOX13,SOX2,SOX9,SPACA7,SPINK5,SPN,SPOCK1,SPOCK2,SRC,SRF,STX3,STX4,SYK,TACSTD2,TARM1,TBCD,TEK,TESC,TESPA1,TFE3,TFRC,TGFB1,TGFB2,TGFBI,TGFBR2,TGM2,THBS1,THY1,TIGIT,TMEM131L,TMIGD2,TNC,TNF,TNFAIP8L2,TNFRSF13C,TNFRSF14,TNFRSF18,TNFRSF21,TNFSF11,TNFSF13B,TNFSF14,TNFSF18,TNFSF9,TNR,TRAF2,TRAF6,TRIOBP,UBASH3B,UTRN,VAV1,VAV3,VCAM1,VEGFA,VEGFC,VIT,VNN1,VPS33B,VSIG4,VTCN1,VTN,VWC2,WASHC2C,WNT1,WNT3A,WNT4,WNT5A,XBP1,XCL1,YES1,YTHDF2,ZAP70,ZBTB1,ZBTB16,ZBTB7B,ZC3H8,ZEB1,ZMIZ1,ZNF645,ZNF683,ZNF703,ZP3,ZP4	TetrapodAncestor	300
GO.Biological.Process	GO:0030334	regulation.of.cell.migration	1	1e-300	1e-300	1e-300	1.239195e+0	AAMP,ABHD2,ABHD6,ABI3,ABL1,ABR,ACE,ACKR3,ACTN4,ACVR1B,ACVRL1,ADA,ADAM15,ADAM8,ADAM9,ADAMTS9,ADARB1,ADGRA2,ADGRB1,ADGRG1,ADGRG3,ADIPOQ,ADIPOR1,ADORA1,ADORA3,ADRA2A,AGT,AGTR2,AIF1,AJUBA,AKT2,ALOX15B,AMOT,AMOTL1,ANGPT1,ANGPT2,ANGPT4,ANO6,ANXA1,ANXA3,APC,APEX1,APOD,APOE,APOH,APP,AQP1,ARAP3,ARHGAP4,ARHGDIB,ARHGEF2,ARHGEF39,ARHGEF7,ARID2,ARPIN,ATOH8,ATP5A1,ATP8A1,BAG4,BCAR1,BCAS3,BCL2,BCR,BDKRB1,BMP10,BMP2,BMP4,BMP5,BMP7,BMPER,BMPR1A,BMPR2,BRAF,BST1,BST2,C16orf45,C1QBP,C3AR1,C5,C5orf30,CALR,CAMK1D,CAMSAP3,CAPN7,CARMIL1,CARMIL2,CBLL1,CCBE1,CCL1,CCL11,CCL19,CCL2,CCL21,CCL28,CCL3,CCL4,CCL5,CCL7,CCL8,CCR1,CCR2,CCR6,CCR7,CD274,CD300A,CD40,CD74,CDH13,CDK5,CEMIP,CERS2,CGA,CHRD,CIB1,CITED2,CLASP1,CLASP2,CMKLR1,COL18A1,COL1A1,COL3A1,CORO1A,CORO1B,CPEB1,CPNE3,CREB3,CRK,CSF1,CSF1R,CSNK2B,CTSH,CX3CL1,CX3CR1,CXCL1,CXCL10,CXCL11,CXCL13,CXCL14,CXCL16,CXCL2,CXCL3,CXCL5,CXCL6,CXCL8,CXCL9,CXCR3,CYGB,CYP19A1,CYP1B1,CYR61,DAB2,DAB2IP,DACH1,DAPK2,DAPK3,DCN,DDR2,DDRGK1,DDT,DDX58,DIAPH1,DLC1,DLG5,DLL4,DMTN,DOCK10,DOCK4,DOCK5,DOCK8,DPEP1,DPYSL3,DRD1,DRD2,DUSP10,EDN1,EDN2,EDN3,EFNA1,EGF,EGFR,ELP3,EMP2,ENG,ENPP2,ENSG00000259753,ENSG00000260272,EPB41L4B,EPB41L5,EPHA1,EPHA2,ERBB4,ETS1,EVL,F10,F2R,F2RL1,F3,F7,FADD,FAM60A,FAM83H,FAM89B,FBXO31,FER,FERMT3,FGF1,FGF10,FGF16,FGF18,FGF2,FGF4,FGF7,FGFR1,FGFR1OP,FGR,FLCN,FLNA,FLRT2,FLT1,FLT4,FN1,FOXC2,FOXF1,FOXO4,FRMD5,FSHB,FUZ,GAB1,GAS6,GATA3,GCNT2,GDF2,GLIPR2,GNA12,GNA13,GNRH1,GPER1,GPLD1,GPNMB,GPR18,GPR183,GPSM3,GRB7,GREM1,GSTP1,GTSE1,HACE1,HAS2,HBEGF,HDAC4,HDAC5,HDAC7,HDAC9,HGF,HIF1A,HMCN2,HMGB1,HMOX1,HRAS,HRG,HSPA5,HSPB1,IDH2,IFITM1,IFNG,IGF1,IGF1R,IGFBP5,IGSF10,IL12A,IL1A,IL1B,IL1R1,IL23A,IL24,IL33,IL4,IL6,IL6R,INS,INSL3,INSM1,IQGAP1,IRS2,ITGA2,ITGA2B,ITGA3,ITGA4,ITGA5,ITGAV,JAG1,JAG2,JAK2,JAM3,JCAD,JUN,KANK1,KARS,KIF20B,KITLG,KLF4,KLRK1,KRIT1,KRT16,LAMA1,LAMA2,LAMA3,LAMA4,LAMA5,LAMB1,LBP,LDB2,LDLRAD4,LEF1,LGALS3,LGALS9,LGR6,LMNA,LMO4,LPAR1,LRCH1,LRIG2,LRP1,LRRC15,LYN,MACF1,MADCAM1,MAGI2,MAPK1,MAPK14,MAPK3,MAPRE1,MARVELD3,MCAM,MCC,MCTP1,MDM2,MEOX2,MET,MIA3,MIEN1,MIF,MIIP,MINK1,MMP10,MMP14,MMP28,MMP9,MMRN2,MOSPD2,MPP1,MSN,MTA2,MTOR,MYADM,MYLK,MYO1C,MYOCD,MYPN,MYSM1,NAV3,NBL1,NCK1,NCKAP1L,NDRG4,NF1,NF2,NIPBL,NISCH,NKX6-1,NOG,NOTCH1,NOV,NOX4,NRG1,NRG3,NRP1,NRP2,NTF3,NTRK3,NUMB,ONECUT1,P2RX4,P2RY6,PADI2,PAK1,PAK3,PARD6B,PBLD,PDCD10,PDCD6,PDGFA,PDGFB,PDGFC,PDGFD,PDGFRB,PDPK1,PDPN,PF4,PF4V1,PFN1,PFN2,PHLDA2,PHLDB2,PIK3CD,PIK3R1,PITX2,PKP2,PLA2G7,PLAA,PLAU,PLCB1,PLCG1,PLET1,PLPP3,PLVAP,PLXNA1,PLXNA2,PLXNB2,PLXND1,PODN,PODXL,PPARD,PPARG,PPARGC1A,PPBP,PPM1F,PRCP,PREX1,PRKCA,PRKCE,PRKD1,PRKD2,PRKX,PROX1,PRR5L,PTAFR,PTEN,PTGER4,PTK2,PTK2B,PTN,PTP4A1,PTPN23,PTPRG,PTPRJ,PTPRK,PTPRM,PTPRR,PTPRU,PYCARD,RAB25,RAC1,RAC2,RAP2A,RAP2B,RAP2C,RAPGEF2,RARRES2,RCC2,RDX,RECK,RELN,RET,RETN,RFFL,RGCC,RHOD,RIPK3,RIPOR1,RIPOR2,RNF20,RNF41,ROBO1,ROBO4,ROCK2,ROR2,RRAS,RRAS2,RREB1,RTN4,RUFY3,S100A14,S100A7,S1PR1,SASH1,SCAI,SCARB1,SCRT1,SCRT2,SDC4,SDCBP,SELENOK,SELP,SEMA3A,SEMA3C,SEMA4A,SEMA4D,SEMA5A,SEMA6A,SEMA6D,SERPINB3,SERPINE2,SFRP1,SFRP2,SGK1,SH3BP1,SLC8A1,SLC8B1,SLC9A3R1,SLIT2,SLURP1,SMAD7,SMURF2,SNAI1,SNAI2,SOD2,SORL1,SOX14,SOX9,SP100,SPAG9,SPATA13,SPHK1,SPRED1,SPRY2,SRC,SRCIN1,SRF,SRGAP1,SRGAP2,SRGAP2B,SRGAP2C,SRGAP3,SRPX2,SST,STAP1,STARD13,STC1,STK24,STK26,STRAP,STX4,SUN2,SYDE1,SYNE2,SYNJ2BP,TAC1,TACSTD2,TBCCD1,TBX5,TDGF1,TEK,TERT,TGFB1,TGFB2,TGFBR1,TGFBR2,THBS1,THBS4,THY1,TIAM1,TIE1,TIMP1,TIRAP,TMEFF2,TMIGD1,TMIGD3,TMSB4Y,TNF,TNFAIP6,TNFRSF14,TNFRSF18,TNFSF14,TNFSF18,TP53INP1,TRIB1,TRIM32,TRIP6,ULK4,UNC5C,UNC5D,UTS2,VASH1,VCL,VEGFA,VEGFB,VEGFC,VEGFD,VIL1,VTN,WNT11,WNT4,WNT5A,WNT7A,XBP1,XCL1,ZC3H12A,ZMYND8,ZNF580,ZNF609,ZNF703,ZP3	TetrapodAncestor	300
GO.Biological.Process	GO:0031400	negative.regulation.of.protein.modification.process	1	1e-300	1e-300	1e-300	1.332997e+0	ABL1,ACER2,ADAR,ADARB1,ADGRB1,ADIPOQ,ADORA2A,AIDA,AKT1S1,AMBP,ANAPC1,ANAPC11,ANAPC16,ANAPC2,ANAPC4,ANAPC5,ANGPT1,APC,APOE,ARRB1,ARRB2,ASH1L,ASPN,ATF3,ATG14,ATG5,ATP2B4,BAK1,BAX,BCOR,BDKRB1,BDKRB2,BGN,BMP4,BMP7,BRCA1,C14orf166,C1QL4,C3orf33,C9orf72,CACTIN,CALM1,CALM2,CALM3,CAMK2N1,CAMK2N2,CASP3,CAV1,CAV3,CBL,CBLB,CBLC,CCNB1,CD109,CD300A,CDC16,CDC20,CDC23,CDC26,CDC27,CDK1,CDK2,CDK5,CDK5RAP1,CDKN1A,CDKN1B,CDKN1C,CDKN2A,CDKN2B,CDKN2C,CDKN2D,CEBPA,CEP85,CHAD,CHMP6,CHORDC1,CHP1,CIB1,CISH,CNKSR3,CRTAP,CRY1,CRY2,CRYBA1,CSK,CTBP1,CTDSP1,CTDSP2,CTDSPL,CTNNB1,DAB2IP,DACT1,DBNDD2,DCN,DDIT4,DEPTOR,DGKQ,DKK1,DLG1,DMD,DMTN,DNAJA1,DNAJC10,DNMT3B,DTNBP1,DTX3L,DUS2,DUSP1,DUSP10,DUSP16,DUSP18,DUSP19,DUSP2,DUSP21,DUSP22,DUSP26,DUSP3,DUSP6,DUSP7,DUSP8,DUSP9,DVL1,EFNA1,EIF3A,ENG,ENPP1,EPHA1,EPHB2,ERRFI1,EZR,F2RL1,FABP4,FAM129A,FAM212A,FAM212B,FBLN1,FBXO5,FBXO7,FGFR1OP,FKBP1A,FKBP1B,FKTN,FLCN,FLRT1,FLRT2,FLRT3,FOXM1,FOXO1,FOXP3,FRY,FSCB,FXYD1,FZR1,G6PD,GADD45A,GADD45B,GBA,GFRA2,GGNBP2,GMFB,GMFG,GNAQ,GNL3L,GP1BA,GPD1L,GPER1,GPRC5A,GPS1,GREM1,GSKIP,GSTP1,H2AFY,HDAC2,HDAC3,HDAC8,HEXIM1,HEXIM2,HGF,HHATL,HHEX,HINT2,HMG20A,HMG20B,HMGCR,HSPB1,HSPH1,IBTK,IGBP1,IGF1R,IKBKB,IL1B,IL2,IL6,INCA1,INPP5J,INPP5K,INSM1,IRAK3,ISG15,ITCH,JARID2,JUN,KAT2B,KDM3A,KDM4C,KDM5A,KIRREL1,KIRREL2,KLF15,KLF4,LATS1,LATS2,LAX1,LDLRAD4,LEMD2,LIF,LIMK1,LMO3,LRP5,LRP6,LRRC15,LRRC19,LRRC3,LRRC3C,LRRC4,LRRC4C,LRRC66,LRRK2,LRRTM1,LRRTM3,LRRTM4,LRTM1,LRTM2,LYN,MAD2L1,MAD2L2,MAPK8IP1,MARVELD3,MAS1,MASTL,MBIP,MECOM,MECP2,MEN1,MGAT4D,MICAL1,MLLT1,MLXIPL,MTF2,MTOR,MVP,MYADM,MYC,MYOCD,N4BP1,NCK1,NCK2,NCKAP1L,NCOA7,NF1,NF2,NLRP6,NOC2L,NOG,NPM1,NTF3,NTRK3,NUP62,NXN,OGT,OTUB1,OXR1,P2RX7,P3H1,PAFAH1B1,PAK2,PARD3,PARD6A,PARK7,PARP10,PARP14,PAX5,PBK,PBLD,PDCL3,PDE4D,PDPK1,PER1,PER2,PHB,PHF1,PIAS3,PID1,PIH1D1,PIK3R2,PIN1,PINK1,PINX1,PKIA,PKIB,PKIG,PKN1,PLAA,PLK1,PLPP3,PMEPA1,PML,PNKP,PODN,PODNL1,PPARGC1A,PPEF2,PPM1E,PPM1F,PPP1R15A,PPP1R15B,PPP1R16B,PPP1R1A,PPP1R1C,PPP1R8,PPP4R4,PPP5C,PREX1,PRKAG2,PRKAR1A,PRKAR1B,PRKAR2B,PRKCD,PRKCE,PRKCG,PRKCZ,PRKDC,PRKN,PRKRIP1,PRR5L,PSCA,PSEN1,PSMA2,PSMA3,PSMA4,PSMB1,PSMB10,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTEN,PTPA,PTPN1,PTPN22,PTPRJ,PTPRR,PWP1,PYCARD,PYDC1,RANBP9,RAPGEF1,RASD2,RASSF2,RB1,RELA,RGN,RGS14,RGS2,RGS3,RGS4,RNF149,RNF222,ROCK2,RPL11,RPL23,RPL5,RPS27A,RPS3,RPS6KA6,RPS7,RPTOR,RTN4R,RTN4RL2,SAMSN1,SDR16C5,SEMA4D,SENP2,SERPINB3,SFN,SFRP1,SFRP2,SGTA,SH3BP5,SHB,SIRT1,SIRT2,SIRT3,SKI,SLC9A3R1,SLIT2,SMAD4,SMAD7,SMARCB1,SMCR8,SMPD1,SMYD3,SNCA,SNTA1,SNX6,SOCS1,SOCS2,SOCS3,SOCS4,SOCS5,SOCS6,SOCS7,SORL1,SOX4,SPI1,SPINK1,SPOPL,SPRED1,SPRED2,SPRY1,SPRY2,SPRY4,SRCIN1,STK38,STRAP,SUFU,SYNJ2BP,TAF1,TARBP2,TARDBP,TBC1D10C,TERF2IP,TESC,TGFB1,THY1,TIMP3,TINF2,TIPRL,TLR4,TMEM59,TNF,TNFAIP3,TNIP1,TP73,TRAF3IP1,TRIB1,TRIB2,TRIB3,TRIM21,TRIM39,TRIP12,TSC2,TSG101,TSPO,TWIST1,U2AF2,UBASH3B,UBC,UBE2C,UBE2D1,UBE2E1,UBR5,UBXN1,UCHL1,UCN,UFL1,UVSSA,VPS25,VPS28,VRK3,WARS,WEE2,WNK1,WNK2,WNT1,WWTR1,XDH,XRCC1,YWHAB,YWHAE,YWHAG,ZBED3,ZC3H12A,ZFYVE28,ZNF675	TetrapodAncestor	300
GO.Biological.Process	GO:0033993	response.to.lipid	1	1e-300	1e-300	1e-300	1.265834e+0	AACS,AANAT,ABCA1,ABCA2,ABCA3,ABCB4,ABCC2,ABCC8,ABCG1,ABHD2,ABL1,ABL2,ABR,ACACA,ACER2,ACP5,ACSBG1,ACSL1,ADAM9,ADAMTS13,ADCY2,ADCY3,ADCY5,ADCYAP1,ADCYAP1R1,ADH5,ADIPOQ,ADNP2,AGL,AGT,AGTR2,AGXT,AICDA,AIF1,AIFM1,AKAP8,AKIRIN2,ALAD,ALDH3A1,ALPL,ANKRD1,ANXA1,ANXA3,APOA2,APOB,AQP1,AQP3,AR,AREG,ARG1,ARID1A,ARNT2,ARPC1B,ASCL1,ASXL1,ATP1A1,ATP1A2,ATP2B1,AVP,AVPR1A,AXL,BAD,BCHE,BCL2,BCR,BDKRB1,BGLAP,BID,BMP4,BMP6,BMP7,BRCA1,BRINP1,BRINP2,BRINP3,CA2,CA9,CACTIN,CALCOCO1,CALCR,CALR,CARD16,CARD17,CARM1,CASP1,CASP3,CASP8,CASP9,CASR,CAT,CATSPER1,CATSPER2,CATSPER4,CATSPERB,CATSPERD,CAV1,CBL,CCL1,CCL19,CCL2,CCL21,CCL3,CCL5,CCNA2,CCNB1,CCND1,CCNE1,CCR5,CCR7,CD14,CD180,CD27,CD36,CD38,CD40,CD6,CD80,CD86,CD96,CDC73,CDK19,CDK4,CDK6,CDK7,CDKN1A,CDKN1B,CDKN2D,CDO1,CEBPB,CEBPE,CFLAR,CFTR,CHUK,CITED1,CLDN1,CLDN4,CLK2,CMPK2,CNGA3,CNR1,CNR2,COL1A1,CPEB1,CPN1,CPS1,CPT1A,CREB1,CRHBP,CRLS1,CRYAB,CSF2RB,CSF3,CSNK2A1,CSNK2B,CTGF,CTNNB1,CTSH,CX3CR1,CXCL1,CXCL10,CXCL11,CXCL13,CXCL16,CXCL2,CXCL3,CXCL5,CXCL6,CXCL8,CXCL9,CYBA,CYBB,CYP1A1,CYP1A2,CYP24A1,CYP26B1,CYP27B1,CYP7A1,DAB2IP,DAXX,DCN,DDIT4,DDX17,DDX18,DDX5,DDX54,DGAT2,DKK1,DNAJA1,DNM1L,DNMT3A,DNMT3B,DSG1,DSG2,DUSP1,DUSP10,DYNAP,E2F1,EDN1,EDNRB,EEF2,EFNA5,EGFR,EGLN2,EIF4E,EIF4EBP1,ELK1,ENDOG,ENG,EPHA3,EPHX1,EPO,ERRFI1,ESR1,ESR2,ESRRA,ESRRB,ESRRG,ETS1,EZH2,F2R,F7,FABP3,FAM210B,FAS,FASLG,FBXO32,FDX1,FER,FFAR1,FFAR2,FFAR3,FGF10,FGF23,FGFR2,FHL2,FIBIN,FIS1,FKBP4,FOS,FOSB,FOSL1,FOXA1,FOXO1,FOXP2,FZD10,FZD4,FZD7,GABRB1,GATA2,GATA4,GBA,GCH1,GDAP1,GH1,GHRHR,GHSR,GIP,GIPR,GJA1,GJB3,GLB1,GLDC,GNAI1,GNG12,GNG2,GNRH1,GOT1,GPER1,GPLD1,GPR83,GRIP1,GSTP1,H2AFZ,HAMP,HAVCR2,HCK,HDAC2,HDAC5,HDAC8,HEY1,HMGB1,HMGB2,HMGCL,HMGCS1,HNF4A,HNF4G,HNMT,HNRNPA0,HNRNPD,HNRNPU,HPGD,HSD11B2,HSD17B2,HSF1,HTR1B,HTR5A,HTRA2,ID3,IDO1,IFNAR1,IFNB1,IFNG,IGF2R,IGFBP2,IGFBP7,IHH,IL10,IL10RA,IL12A,IL12B,IL12RB2,IL13,IL15,IL18,IL18BP,IL1B,IL1RN,IL22,IL23R,IL24,IL6,INHBA,INSIG2,IRAK1,IRAK3,IRF3,IRF8,IRGM,ISL1,ITGA2,JAK2,JUN,JUNB,KAT5,KCNJ11,KCNJ8,KCNK4,KCNMB1,KDM3A,KIF18A,KLF4,KLF9,KLRK1,KRAS,KRT13,LBP,LCN2,LDLR,LEF1,LEP,LGALS9,LILRB2,LITAF,LOX,LOXL1,LPAR1,LRP6,LRP8,LTBR,LTK,LY96,LYN,MAOB,MAPK1,MAPK14,MAPK3,MAPK8,MAPKAPK2,MAPKAPK3,MBD1,MBD2,MBD3,MDK,MDM2,MED13,MED14,MED17,MED24,MED30,MED4,MEF2C,METTL21C,MGARP,MGST1,MGST2,MLC1,MMP15,MPO,MRC1,MSN,MSTN,MSX2,MTDH,MYB,MYOD1,MYOG,NASP,NCOA1,NCOA3,NCOA4,NCOA6,NEFL,NFATC4,NFKB1,NFKB2,NFKBIB,NGFR,NKX3-1,NLRP7,NME1,NME2,NOCT,NOS2,NOS3,NOTCH1,NPAS4,NPC1,NQO1,NR0B1,NR0B2,NR1D1,NR1D2,NR1H2,NR1H3,NR1H4,NR1I2,NR2C1,NR2C2,NR2E3,NR2F6,NR3C1,NR4A1,NR4A2,NR4A3,NR5A2,NRIP1,NTRK3,NTSR1,NUGGC,OGG1,OPRK1,OPRL1,OPRM1,OR51E2,OSR1,OTUD5,OVCA2,OXT,OXTR,P2RX7,P2RY4,P2RY6,PABPN1,PADI2,PAF1,PALM3,PAM,PAPPA,PAQR5,PAQR6,PAQR7,PAQR8,PARP1,PAX2,PCK1,PCK2,PCNA,PDCD7,PDE4B,PDE4D,PDGFRB,PDK3,PELI1,PENK,PF4,PF4V1,PFKFB1,PGR,PGRMC2,PHB,PHEX,PIAS1,PIAS2,PID1,PIM1,PITX2,PLAA,PLCG2,PLN,PLPP1,PLSCR4,PMEPA1,PMVK,POU4F1,PPARA,PPARD,PPARG,PPARGC1A,PPARGC1B,PPBP,PRDX3,PRKAA1,PRKAA2,PRKCE,PRPF8,PRSS33,PSPH,PTAFR,PTCH1,PTEN,PTGDR,PTGER1,PTGER2,PTGER4,PTGES,PTGFR,PTGIR,PTH,PTK2B,PTK7,PTN,PTPN22,PTPRU,PYCARD,RAMP2,RARA,RARB,RARG,RASGRP4,RB1,RBBP7,RBBP8,RBFOX2,RBM14,RBP4,RELA,RELT,REN,REST,RET,RIPK2,RNF14,RNF4,ROCK2,RORB,RORC,RPS6KA3,RUVBL2,RWDD1,RXRA,RXRB,RXRG,S100A14,S100A7,S100A8,S100B,SAFB,SCARB1,SCGB1A1,SELE,SELP,SETX,SFRP1,SHPK,SLC10A3,SLC11A1,SLC34A1,SLC6A4,SLIT2,SLIT3,SLPI,SMAD2,SMARCD1,SMO,SMYD3,SNCA,SNRNP70,SNW1,SOCS2,SOX10,SOX30,SOX9,SPON2,SPP1,SRC,SRD5A1,SRD5A2,SREBF1,SRR,SST,SSTR1,SSTR2,SSTR3,SSTR4,SSTR5,STAP1,STAR,STC1,STC2,STRA8,STXBP1,T,TAC1,TACR3,TADA3,TAT,TBX1,TBXA2R,TEAD2,TESC,TFPI,TGFB1,TGFB1I1,TGFB2,TGFBR1,TGFBR2,TH,THBD,THBS1,THRA,THRAP3,THRB,TICAM1,TICAM2,TIE1,TIMP4,TIRAP,TLR2,TLR4,TLR5,TMEM161A,TNC,TNF,TNFAIP3,TNFRSF10A,TNFRSF10B,TNFRSF10C,TNFRSF10D,TNFRSF11A,TNFRSF11B,TNFRSF14,TNFRSF18,TNFRSF1A,TNFRSF1B,TNFRSF21,TNFRSF25,TNFRSF4,TNFRSF8,TNFRSF9,TNIP1,TNIP2,TNIP3,TPCN2,TPH2,TRAF6,TREM2,TRIB1,TRIM25,TRIM6,TRIM63,TRIML2,TRIP4,TSHB,TSPO,TWF2,TXNIP,TYMS,TYR,UBE2L3,UBE3A,UBR5,UCN,UCN3,UCP1,UCP2,UCP3,UGT1A1,UPF1,USP8,UTS2,VCAM1,VDR,VPS4B,WDR35,WFDC1,WNT10B,WNT11,WNT3,WNT3A,WNT5A,WNT6,WNT7A,WNT7B,WNT8A,WNT8B,WNT9A,WNT9B,XBP1,XRCC5,XRN1,YAP1,YES1,YWHAH,YY1,ZC3H12A,ZFP36,ZFP36L1,ZFP36L2,ZNF703	TetrapodAncestor	300
GO.Biological.Process	GO:0040012	regulation.of.locomotion	1	1e-300	1e-300	1e-300	1.216577e+0	AAMP,ABHD2,ABHD6,ABI3,ABL1,ABL2,ABR,ACE,ACKR3,ACTN4,ACVR1B,ACVRL1,ADA,ADAM15,ADAM8,ADAM9,ADAMTS9,ADARB1,ADGRA2,ADGRB1,ADGRG1,ADGRG3,ADIPOQ,ADIPOR1,ADORA1,ADORA2A,ADORA3,ADRA2A,AGER,AGT,AGTR2,AIF1,AJUBA,AKT2,ALOX15B,AMOT,AMOTL1,ANGPT1,ANGPT2,ANGPT4,ANO6,ANXA1,ANXA3,AP1AR,APC,APEX1,APOD,APOE,APOH,APP,AQP1,ARAP3,ARHGAP18,ARHGAP4,ARHGDIB,ARHGEF2,ARHGEF39,ARHGEF7,ARID2,ARPIN,ARRDC3,ARTN,ATOH8,ATP5A1,ATP8A1,BAG4,BBS4,BCAR1,BCAS3,BCL2,BCR,BDKRB1,BMP10,BMP2,BMP4,BMP5,BMP7,BMPER,BMPR1A,BMPR2,BRAF,BST1,BST2,BTC,BVES,C16orf45,C1QBP,C3AR1,C5,C5orf30,CALR,CAMK1D,CAMSAP3,CAPN7,CARMIL1,CARMIL2,CASR,CATSPER1,CAV2,CBLL1,CCBE1,CCDC125,CCL1,CCL11,CCL19,CCL2,CCL21,CCL28,CCL3,CCL4,CCL5,CCL7,CCL8,CCR1,CCR2,CCR4,CCR6,CCR7,CD274,CD300A,CD40,CD74,CD81,CDH13,CDK5,CDK6,CEMIP,CERS2,CFAP20,CGA,CHMP2A,CHMP2B,CHMP3,CHMP4B,CHMP4C,CHRD,CHRM1,CHRM4,CIB1,CITED2,CLASP1,CLASP2,CMKLR1,COL18A1,COL1A1,COL3A1,CORO1A,CORO1B,CPEB1,CPNE3,CREB3,CRK,CSF1,CSF1R,CSNK2B,CTNNA1,CTSH,CX3CL1,CX3CR1,CXCL1,CXCL10,CXCL11,CXCL13,CXCL14,CXCL16,CXCL2,CXCL3,CXCL5,CXCL6,CXCL8,CXCL9,CXCR3,CXCR4,CYGB,CYP19A1,CYP1B1,CYR61,DAB2,DAB2IP,DACH1,DAPK2,DAPK3,DCN,DDB1,DDR2,DDRGK1,DDT,DDX58,DIAPH1,DLC1,DLG5,DLL4,DMTN,DOCK10,DOCK4,DOCK5,DOCK8,DPEP1,DPYSL3,DRD1,DRD2,DRD3,DSCAM,DUSP10,EDN1,EDN2,EDN3,EFNA1,EFNB2,EGF,EGFR,ELP3,EMP2,ENG,ENPP2,ENSG00000259753,ENSG00000260272,EPB41L4B,EPB41L5,EPCAM,EPHA1,EPHA2,EPPIN,EPPIN-WFDC6,ERBB2,ERBB4,EREG,ETS1,EVL,F10,F2R,F2RL1,F3,F7,FADD,FAM60A,FAM83H,FAM89B,FBLN1,FBXO31,FBXO7,FER,FERMT3,FES,FGF1,FGF10,FGF16,FGF18,FGF2,FGF4,FGF7,FGFR1,FGFR1OP,FGR,FLCN,FLNA,FLRT2,FLT1,FLT4,FN1,FOXC2,FOXF1,FOXO4,FRMD5,FSHB,FUZ,GAB1,GAS6,GATA3,GCNT2,GDF2,GHSR,GLIPR2,GNA12,GNA13,GNRH1,GPER1,GPLD1,GPNMB,GPR18,GPR183,GPSM3,GRB7,GREM1,GSTP1,GTSE1,HACE1,HAS2,HBEGF,HDAC4,HDAC5,HDAC7,HDAC9,HGF,HIF1A,HMCN2,HMGB1,HMOX1,HRAS,HRG,HSPA5,HSPB1,HTR1D,IDH2,IFITM1,IFNG,IGF1,IGF1R,IGFBP5,IGSF10,IL12A,IL16,IL1A,IL1B,IL1R1,IL23A,IL24,IL33,IL4,IL6,IL6R,INS,INSL3,INSM1,IQCF1,IQGAP1,IRS2,ITGA2,ITGA2B,ITGA3,ITGA4,ITGA5,ITGAV,JAG1,JAG2,JAK2,JAM3,JCAD,JUN,KANK1,KARS,KIF20B,KITLG,KLF4,KLRK1,KRIT1,KRT16,LAMA1,LAMA2,LAMA3,LAMA4,LAMA5,LAMB1,LBP,LDB2,LDLRAD4,LEF1,LGALS3,LGALS9,LGR6,LMNA,LMO4,LPAR1,LRCH1,LRIG2,LRP1,LRRC15,LRRK2,LYN,MACF1,MADCAM1,MAGI2,MAPK1,MAPK14,MAPK3,MAPRE1,MARVELD3,MCAM,MCC,MCTP1,MDM2,MEGF8,MEMO1,MEOX2,MET,MIA3,MID2,MIEN1,MIF,MIIP,MINK1,MKKS,MMP10,MMP14,MMP28,MMP9,MMRN2,MOSPD2,MPP1,MSN,MTA2,MTOR,MYADM,MYLK,MYO1C,MYOCD,MYPN,MYSM1,NAV3,NBL1,NCK1,NCKAP1L,NDRG4,NF1,NF2,NIPBL,NISCH,NKX6-1,NOG,NOTCH1,NOV,NOX4,NRG1,NRG2,NRG3,NRG4,NRP1,NRP2,NTF3,NTRK3,NUMB,ONECUT1,OPRK1,P2RX4,P2RY6,PADI2,PAK1,PAK3,PARD6B,PBLD,PC,PDCD10,PDCD6,PDGFA,PDGFB,PDGFC,PDGFD,PDGFRB,PDPK1,PDPN,PF4,PF4V1,PFN1,PFN2,PGAM4,PHLDA2,PHLDB2,PHPT1,PIK3CD,PIK3R1,PIN1,PITX2,PKN1,PKP2,PLA2G7,PLAA,PLAU,PLCB1,PLCG1,PLET1,PLPP3,PLVAP,PLXNA1,PLXNA2,PLXNA3,PLXNA4,PLXNB2,PLXND1,PML,PODN,PODXL,PPARD,PPARG,PPARGC1A,PPBP,PPM1F,PRCP,PREX1,PRKCA,PRKCE,PRKD1,PRKD2,PRKX,PROX1,PRR5L,PTAFR,PTEN,PTGER4,PTK2,PTK2B,PTN,PTP4A1,PTPN23,PTPRG,PTPRJ,PTPRK,PTPRM,PTPRO,PTPRR,PTPRU,PYCARD,RAB25,RAC1,RAC2,RAF1,RAP2A,RAP2B,RAP2C,RAPGEF2,RARRES2,RCC2,RDX,RECK,RELN,RET,RETN,RFFL,RGCC,RGN,RHOD,RIPK3,RIPOR1,RIPOR2,RNASE10,RNF20,RNF41,ROBO1,ROBO2,ROBO4,ROCK2,ROR2,RRAS,RRAS2,RREB1,RTN4,RUFY3,S100A14,S100A7,S1PR1,SASH1,SCAI,SCARB1,SCG2,SCRT1,SCRT2,SDC4,SDCBP,SELENOK,SELP,SEMA3A,SEMA3C,SEMA4A,SEMA4D,SEMA5A,SEMA6A,SEMA6D,SEMG1,SEMG2,SERPINB3,SERPINE2,SFRP1,SFRP2,SGK1,SH3BP1,SLC26A5,SLC8A1,SLC8B1,SLC9A3R1,SLIT2,SLURP1,SMAD7,SMURF2,SNAI1,SNAI2,SNCA,SOD2,SORL1,SOX14,SOX9,SP100,SPAG9,SPATA13,SPHK1,SPOCK2,SPOCK3,SPRED1,SPRY2,SRC,SRCIN1,SRF,SRGAP1,SRGAP2,SRGAP2B,SRGAP2C,SRGAP3,SRPX2,SST,STAP1,STARD13,STC1,STK24,STK26,STRAP,STX3,STX4,SUN2,SYDE1,SYNE2,SYNJ2BP,TAC1,TAC4,TACR3,TACSTD2,TBCCD1,TBX5,TDGF1,TEK,TERT,TGFB1,TGFB2,TGFBR1,TGFBR2,THBS1,THBS4,THY1,TIAM1,TIE1,TIMP1,TIRAP,TMEFF2,TMIGD1,TMIGD3,TMSB4Y,TNF,TNFAIP6,TNFRSF14,TNFRSF18,TNFSF14,TNFSF18,TP53INP1,TRIB1,TRIM11,TRIM13,TRIM21,TRIM25,TRIM28,TRIM32,TRIM35,TRIM5,TRIM62,TRIM8,TRIP6,TSG101,TUBB2B,TWIST1,ULK4,UNC5C,UNC5D,USP14,UTS2,VAPA,VASH1,VCL,VEGFA,VEGFB,VEGFC,VEGFD,VIL1,VPS35,VPS37B,VPS4A,VPS4B,VTN,WNT11,WNT3,WNT3A,WNT4,WNT5A,WNT7A,XBP1,XCL1,ZC3H12A,ZMYND8,ZNF580,ZNF609,ZNF703,ZP3	TetrapodAncestor	300
GO.Biological.Process	GO:0042326	negative.regulation.of.phosphorylation	1	1e-300	1e-300	1e-300	1.340298e+0	ABL1,ADAR,ADARB1,ADIPOQ,ADORA2A,AHSG,AIDA,AJUBA,AKT1S1,AMBP,ANGPT1,APC,APOE,ARRB1,ARRB2,ASH1L,ASPN,ATF3,ATG14,BAK1,BAX,BDKRB1,BDKRB2,BGN,BMP4,BMP7,C14orf166,C1QL4,C3orf33,C9orf72,CACTIN,CALM1,CALM2,CALM3,CAMK2N1,CAMK2N2,CASP3,CAV1,CAV3,CBL,CBLB,CBLC,CCNB1,CD109,CD300A,CDK5RAP1,CDKN1A,CDKN1B,CDKN1C,CDKN2A,CDKN2B,CDKN2C,CDKN2D,CEBPA,CEP85,CHAD,CHMP6,CHORDC1,CHP1,CIB1,CISH,CNKSR3,COX11,CRYBA1,CSK,CTDSP1,CTDSP2,CTDSPL,DAB2IP,DACT1,DBNDD2,DCN,DDIT4,DEPTOR,DGKQ,DKK1,DLG1,DMD,DMTN,DNAJA1,DNAJC10,DNAJC15,DTNBP1,DUS2,DUSP1,DUSP10,DUSP16,DUSP18,DUSP19,DUSP2,DUSP21,DUSP22,DUSP26,DUSP3,DUSP6,DUSP7,DUSP8,DUSP9,DVL1,DYNLL1,EFNA1,EIF3A,ENG,ENPP1,EPHA1,EPHB2,ERRFI1,EZR,F2RL1,FABP4,FAM129A,FAM212A,FAM212B,FBLN1,FBP1,FBXO7,FGFR1OP,FKBP1A,FKTN,FLCN,FLRT1,FLRT2,FLRT3,FOXA2,FOXM1,FOXO1,GADD45A,GADD45B,GBA,GCKR,GFRA2,GGNBP2,GMFB,GMFG,GNAQ,GP1BA,GPD1L,GPER1,GPRC5A,GPS1,GRB10,GREM1,GSKIP,GSTP1,H2AFY,HDAC3,HDAC4,HEXIM1,HEXIM2,HGF,HHEX,HMGCR,HNRNPU,HSPB1,HSPH1,IBTK,IGBP1,IGF1R,IL1B,IL2,IL6,INCA1,INHA,INHBA,INPP5J,INPP5K,INSM1,IRAK3,IRS2,ITCH,JUN,KAT2B,KIRREL1,KIRREL2,KLF4,LATS1,LATS2,LAX1,LDLRAD4,LEMD2,LIF,LMO3,LRP5,LRP6,LRRC15,LRRC19,LRRC3,LRRC3C,LRRC4,LRRC4C,LRRC66,LRRK2,LRRTM1,LRRTM3,LRRTM4,LRTM1,LRTM2,LYN,MAPK8IP1,MAPT,MARVELD3,MAS1,MBIP,MECOM,MEN1,MICAL1,MLLT1,MLXIPL,MSTN,MTOR,MVP,MYADM,MYC,MYOCD,MYOG,NCK1,NCK2,NF1,NF2,NLRP6,NOG,NPM1,NPRL2,NTF3,NTRK3,NUP62,P2RX7,PAFAH1B1,PAK2,PARD3,PARD6A,PARK7,PARP14,PBK,PBLD,PDE12,PDE4D,PDPK1,PER1,PFKFB1,PHB,PID1,PIK3IP1,PIK3R2,PIN1,PINK1,PKIA,PKIB,PKIG,PKN1,PLK1,PLPP3,PMEPA1,PODN,PODNL1,PPARA,PPARGC1A,PPEF2,PPIF,PPM1E,PPM1F,PPP1R15A,PPP1R15B,PPP1R1A,PPP1R1C,PPP2R5A,PPP5C,PRDX3,PREX1,PRKAG2,PRKAR1A,PRKAR1B,PRKAR2B,PRKCD,PRKCZ,PRKDC,PRKN,PRKRIP1,PRR5L,PSCA,PSEN1,PSMD10,PTEN,PTPN1,PTPN22,PTPRJ,PTPRR,PWP1,PYCARD,PYDC1,RANBP9,RAPGEF1,RASSF2,RB1,RGN,RGS14,RGS2,RGS3,RGS4,RNF149,RPS6KA6,RPTOR,RTN4R,RTN4RL2,RUBCN,SAMSN1,SEMA4D,SERPINB3,SFN,SFRP1,SFRP2,SH3BP5,SHB,SIRT1,SIRT2,SIRT3,SIRT6,SLC9A3R1,SLIT2,SMAD4,SMAD7,SMCR8,SMPD1,SMYD3,SNCA,SNX6,SOCS1,SOCS2,SOCS3,SOCS4,SOCS5,SOCS6,SOCS7,SORL1,SPINK1,SPRED1,SPRED2,SPRY1,SPRY2,SPRY4,SRCIN1,STAP1,STK38,STRAP,SYNJ2BP,TARBP2,TARDBP,TBC1D10C,TERF2IP,TESC,TGFB1,THY1,TIGAR,TIMP3,TLR4,TNFAIP3,TNIP1,TP73,TRAF3IP1,TRIB1,TRIB2,TRIB3,TSC2,TSG101,TWIST1,UBASH3B,UCHL1,UVSSA,VPS25,VRK3,WARS,WEE2,WNK1,WNK2,WWTR1,XDH,YWHAG,ZBED3,ZC3H12A,ZFYVE28,ZNF675	TetrapodAncestor	300
GO.Biological.Process	GO:0042327	positive.regulation.of.phosphorylation	1	1e-300	1e-300	1e-300	1.220503e+0	ABI1,ABL1,ACE,ACKR3,ACSL1,ACVR1B,ACVR2A,ACVR2B,ACVRL1,ADAM8,ADAM9,ADCY2,ADCY3,ADCY4,ADCY5,ADCY8,ADCYAP1,ADIPOQ,ADNP,ADORA1,ADORA2B,ADRA1A,ADRA1B,ADRA2A,ADRA2B,ADRA2C,ADRB2,ADRB3,AFAP1L2,AGER,AGT,AIF1,AJUBA,AKAP13,AKT2,ALK,ALKAL1,ALOX15,ALS2,AMBRA1,ANGPT1,ANGPT4,ANKRD6,APLN,APLNR,APP,AR,ARAF,AREG,ARHGAP8,ARHGEF2,ARL2BP,ARL6IP5,ARRB1,ARRB2,ATG14,ATM,ATP2B4,ATP6AP1,AVP,AVPI1,AXIN2,BAD,BAG4,BAK1,BANK1,BAX,BCAR3,BCL10,BCL2,BMP10,BMP15,BMP2,BMP4,BMP5,BMP6,BMP7,BMP8A,BMP8B,BMPER,BMPR1A,BMPR2,BRAF,BRAT1,BTBD10,C1QTNF1,C1QTNF2,C3,C5,C8orf4,CAB39,CACUL1,CALCR,CALM1,CALM2,CALM3,CAMK1,CAMKK1,CAMKK2,CAPRIN2,CARD10,CARD14,CARTPT,CAV1,CAV2,CAVIN3,CCDC88A,CCK,CCL1,CCL11,CCL13,CCL14,CCL15,CCL15-CCL14,CCL16,CCL17,CCL18,CCL19,CCL2,CCL21,CCL22,CCL23,CCL3,CCL3L3,CCL4,CCL4L2,CCL5,CCL7,CCL8,CCNB1,CCND1,CCND2,CCND3,CCNH,CCNK,CCNL1,CCNL2,CCNT2,CCR1,CCR7,CD24,CD27,CD36,CD3E,CD40,CD44,CD74,CD80,CD81,CDC25B,CDC42,CDC6,CDH2,CDK1,CDK10,CDK20,CDK5,CDK5R1,CDK5R2,CDK9,CDKN1A,CDKN1B,CDON,CEMIP,CENPE,CFLAR,CHEK2,CHI3L1,CHRNA3,CIB1,CKS1B,CKS2,CLCF1,CLIP3,CLU,CNTF,CNTN1,COPS8,CREBL2,CRK,CRKL,CSF1,CSF1R,CSF3,CSK,CSNK1D,CSNK2B,CSPG4,CTF1,CTGF,CTNNB1,CX3CL1,CXCR4,CYR61,CYSLTR2,DAB1,DAB2,DAB2IP,DAXX,DBF4B,DBNL,DDR2,DDRGK1,DDT,DDX3X,DGKQ,DKK1,DLG1,DNAJC27,DRD2,DRD4,DSCAM,DSTYK,DUSP15,DUSP19,DUSP22,DUSP6,DUSP7,DUSP9,DVL1,DVL3,DYNAP,ECT2,EDA2R,EDAR,EDN1,EDN3,EDNRB,EFNA1,EFNA5,EGF,EGFR,EGR1,EHD4,EIF2AK2,EMP2,ENG,ENPP2,ENTPD5,EPGN,EPHA4,EPHA7,EPHA8,EPO,ERBB2,ERBB4,ERCC6,EREG,ERN1,ERN2,ERP29,ESRRB,ETAA1,EZH2,F2,F2R,F2RL1,FAM129A,FAM20A,FAM58A,FAS,FBXO18,FBXW7,FFAR4,FGD2,FGF1,FGF10,FGF13,FGF18,FGF19,FGF2,FGF20,FGF21,FGF23,FGF4,FGF7,FGF9,FGFR1,FGFR2,FGFR3,FGFR4,FGG,FGR,FIZ1,FLCN,FLOT1,FLT1,FLT3LG,FLT4,FMR1,FRS2,FSHR,FZD1,FZD10,FZD4,FZD5,FZD7,FZD8,GADD45A,GADD45B,GADD45G,GADD45GIP1,GAPDHS,GAREM1,GAS6,GCN1,GCNT2,GDF1,GDF10,GDF11,GDF2,GDF3,GDF5,GDF6,GFRA2,GH1,GHR,GLIPR2,GNG3,GPD1,GPER1,GPNMB,GPR183,GPR37,GPR37L1,GPR55,GPRC5B,GREM1,GRM4,GRM5,GSK3A,HACD3,HAND2,HAVCR2,HAX1,HBEGF,HCLS1,HCRTR1,HDAC2,HDAC3,HES1,HES5,HGF,HIF1A,HIPK2,HMGB1,HMGCR,HRAS,HSF1,HSP90AB1,HSPA2,HSPA5,HSPH1,HTR2A,HTR2B,HTR2C,IAPP,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNB1,IFNE,IFNG,IFNK,IFNL1,IFNW1,IGF1,IGF2,IGFBP4,IKBKG,IL12A,IL12B,IL13,IL15,IL18,IL1B,IL2,IL20,IL21,IL23A,IL23R,IL24,IL26,IL31RA,IL34,IL4,IL5,IL6,IL6R,IL6ST,INAVA,INHA,INHBA,INHBB,INS,IQGAP1,IQGAP3,IRAK1,IRGM,IRS1,ISL1,ITGA1,ITGA5,ITGAV,ITSN1,JAK2,JCAD,JTB,JUN,KARS,KCTD20,KISS1,KITLG,KL,KRAS,KSR1,LACRT,LAMTOR2,LAMTOR3,LAT,LATS1,LCP2,LEFTY1,LEFTY2,LEP,LEXM,LGALS9,LIF,LMO4,LPAR1,LPAR3,LRP4,LRP8,LRRK2,LTBR,LYN,MAD2L2,MADD,MALT1,MAP2K2,MAP2K3,MAP2K4,MAP2K6,MAP2K7,MAP3K1,MAP3K10,MAP3K11,MAP3K12,MAP3K13,MAP3K14,MAP3K15,MAP3K19,MAP3K2,MAP3K21,MAP3K3,MAP3K4,MAP3K5,MAP3K6,MAP3K7,MAP3K7CL,MAP3K8,MAP3K9,MAP4K1,MAP4K3,MAP4K4,MAPK1,MAPK10,MAPK11,MAPK14,MAPK3,MAPK8IP1,MAPK8IP3,MAPKAP1,MAPKAPK2,MAPKAPK3,MAPKAPK5,MAPRE3,MAPT,MARCO,MARK2,MAS1,MID1,MIF,MINK1,MLST8,MLXIPL,MMD,MMD2,MMP9,MOB1B,MOB2,MOS,MRE11,MRNIP,MST1R,MSTN,MTCP1,MTOR,MUC20,MUL1,MUSK,MYDGF,MYOG,NAB2,NBN,NCF1,NCKAP1L,NDRG4,NDST1,NECAB2,NEK1,NEK10,NEK4,NENF,NEURL1,NGF,NKX3-1,NOD1,NOTCH1,NOTCH2,NOX4,NPM1,NPTN,NPY5R,NQO2,NRG1,NRG3,NRK,NRP1,NTF3,NTRK1,NTRK2,NTRK3,OPRD1,OPRK1,OPRL1,OPRM1,OSM,P2RX7,P2RY1,PAK1,PAK2,PAK3,PAK4,PAK5,PARK7,PARP14,PARP16,PARP9,PDCD10,PDE5A,PDE6H,PDE8A,PDGFA,PDGFB,PDGFC,PDGFD,PDGFRB,PDPK1,PEA15,PELI2,PFKFB1,PFKFB2,PFKFB3,PFN2,PHB,PIFO,PIH1D1,PIK3CA,PIK3CG,PIK3R5,PIK3R6,PIN1,PINK1,PKD1,PKD2,PKN1,PLA2G1B,PLA2G2A,PLA2G5,PLA2G6,PLCB1,PLCE1,PLCG1,PLK1,PPARGC1B,PPP1R15A,PPP2R3C,PRKAA1,PRKAA2,PRKACA,PRKACG,PRKAG2,PRKAR1A,PRKAR1B,PRKAR2B,PRKCA,PRKCD,PRKCE,PRKCZ,PRKD1,PRKD2,PRLR,PRMT1,PROK1,PROK2,PROM2,PROX1,PRR5,PRR5L,PSAP,PSEN1,PSMD10,PTEN,PTK2,PTK2B,PTPN1,PTPN11,PTPN22,PYCARD,RAC1,RAD50,RAF1,RALB,RANBP2,RAP1A,RAP1B,RAP2A,RAP2B,RAP2C,RAPGEF1,RAPGEF2,RAPGEF3,RARRES2,RASGRP1,RASSF2,RB1CC1,RBPMS,RELN,RET,RGCC,RICTOR,RIPK1,RIPK2,RIPK3,RIT2,ROBO1,ROCK2,ROR2,RPS27A,RPS3,RPS6KA4,RPS6KA5,RPTOR,RSPO1,RYK,S100A12,S100A7,SAA1,SASH1,SBK2,SDC4,SDCBP,SEMA4C,SEMA4D,SEMA7A,SFRP2,SHC1,SHC2,SIRT1,SLC11A1,SLC27A1,SLC30A10,SMAD4,SMYD3,SNCA,SNX9,SOCS3,SOD1,SORBS3,SOX2,SOX9,SPAG9,SPDYA,SPHK1,SPN,SPRY2,SQSTM1,SRC,SRCIN1,SSTR4,STAP1,STAP2,STK24,STK26,STK4,STRADA,STRADB,SYK,TAB1,TAB2,TAB3,TAOK1,TAOK2,TBK1,TBX1,TCL1A,TCL1B,TDGF1,TEC,TEK,TELO2,TENM1,TERF2IP,TGFB1,TGFB2,TGFBR1,TGFBR2,THBS1,THBS4,THPO,TIAM1,TIGAR,TIMP2,TIRAP,TLR3,TLR4,TLR6,TLR9,TMEM189-UBE2V1,TNF,TNFAIP8L3,TNFRSF10A,TNFRSF10B,TNFRSF11A,TNFRSF14,TNFRSF18,TNFRSF19,TNFRSF1A,TNFSF11,TNFSF15,TNFSF18,TNIK,TNK2,TNKS1BP1,TOM1L1,TP53,TP73,TPD52L1,TPX2,TRAF2,TRAF4,TRAF6,TRAF7,TREM2,TRIM5,TRIM6,TRPC5,TRPC6,TTK,TXN,UBC,UBE2N,UCN,UNC119,UNC5CL,VANGL2,VAPB,VAV2,VAV3,VCP,VEGFA,VEGFC,VLDLR,VTN,WDFY2,WNK1,WNK3,WNT1,WNT11,WNT16,WNT3A,WNT5A,WNT7A,WNT7B,WWC1,XCL1,XCL2,XDH,XRCC5,XRCC6,YES1,ZC3H12A,ZFP91,ZNF16,ZNF622	TetrapodAncestor	300
GO.Biological.Process	GO:0043408	regulation.of.MAPK.cascade	1	1e-300	1e-300	1e-300	1.259408e+0	ABL1,ACKR3,ADAM8,ADAM9,ADCYAP1,ADIPOQ,ADORA1,ADORA2B,ADRA1A,ADRA1B,ADRA2A,ADRA2B,ADRA2C,ADRB2,ADRB3,AGER,AIDA,AJUBA,AKAP13,ALK,ALKAL1,ALOX15,AMBP,ANGPT1,ANKRD6,APIP,APOE,APP,AR,ARAF,ARHGAP8,ARL6IP5,ARRB1,ARRB2,ASH1L,ATF3,ATP6AP1,ATP6AP2,AVPI1,BANK1,BMP10,BMP15,BMP2,BMP4,BMP5,BMP6,BMP7,BMP8A,BMP8B,BMPER,BRAF,C1QL4,C1QTNF1,C1QTNF2,C3orf33,C5,CALCR,CAMK2N1,CARTPT,CAV1,CAV2,CAV3,CAVIN3,CBLC,CCL1,CCL11,CCL13,CCL14,CCL15,CCL15-CCL14,CCL16,CCL17,CCL18,CCL19,CCL2,CCL21,CCL22,CCL23,CCL3,CCL3L3,CCL4,CCL4L2,CCL5,CCL7,CCL8,CCR1,CCR7,CD24,CD27,CD300A,CD36,CD40,CD44,CD74,CD81,CDC42,CDH2,CDK1,CDK10,CDON,CFLAR,CHI3L1,CIB1,CNKSR3,CRK,CRKL,CRYBA1,CSF1R,CSK,CSPG4,CTGF,CTNNB1,CX3CL1,CXCR4,CYR61,CYSLTR2,DAB2IP,DACT1,DAXX,DBNL,DDT,DKK1,DLG1,DNAJA1,DNAJC27,DRD2,DRD4,DSTYK,DTNBP1,DUSP1,DUSP10,DUSP15,DUSP16,DUSP18,DUSP19,DUSP2,DUSP21,DUSP22,DUSP26,DUSP3,DUSP6,DUSP7,DUSP8,DUSP9,DVL3,EDA2R,EDAR,EDN1,EDN3,EFNA1,EGF,EGFR,EIF2AK2,EIF3A,EPGN,EPHA2,EPHA4,EPHA7,EPHA8,EPHB1,EPHB2,EPO,ERBB2,ERBB4,ERCC6,ERN1,ERN2,ERP29,ERRFI1,EZH2,EZR,F2R,F2RL1,FAM58A,FAM83D,FAS,FBLN1,FBXW7,FFAR4,FGD2,FGF1,FGF10,FGF18,FGF19,FGF2,FGF20,FGF21,FGF23,FGF4,FGF9,FGFR1,FGFR2,FGFR3,FGFR4,FGG,FKTN,FLCN,FLT1,FLT4,FN1,FOXM1,FOXO1,FRS2,FSHR,FZD10,FZD4,FZD5,FZD7,FZD8,GADD45A,GADD45B,GADD45G,GAREM1,GAS6,GBA,GCNT2,GDF1,GDF10,GDF11,GDF2,GDF3,GDF5,GDF6,GH1,GHR,GLIPR2,GNG3,GPER1,GPNMB,GPR183,GPR37,GPR37L1,GPR55,GPS1,GRB2,GRIK2,GRM4,GSTP1,HACD3,HAND2,HAVCR2,HCRTR1,HDAC3,HGF,HGS,HIPK2,HMGB1,HMGCR,HRAS,HSPH1,HTR2A,HTR2B,HTR2C,IAPP,ID1,IGBP1,IGF1,IGF1R,IGF2,IGFBP4,IKBKG,IL1B,IL26,IL6,INAVA,INHA,INHBA,INHBB,INPP5K,INS,IQGAP1,IQGAP3,IRAK1,IRAK3,ITCH,ITGA1,ITGAV,JAK2,JCAD,JUN,KARS,KISS1,KITLG,KL,KLF4,KRAS,KSR1,LAMTOR2,LAMTOR3,LAX1,LEFTY1,LEFTY2,LEMD2,LEP,LGALS9,LIF,LMO3,LPAR1,LPAR3,LRRK2,LTBR,LYN,MADD,MAGI3,MAP2K2,MAP2K3,MAP2K4,MAP2K6,MAP2K7,MAP3K1,MAP3K10,MAP3K11,MAP3K12,MAP3K13,MAP3K14,MAP3K15,MAP3K2,MAP3K21,MAP3K3,MAP3K4,MAP3K5,MAP3K6,MAP3K7,MAP3K7CL,MAP3K8,MAP3K9,MAP4K1,MAP4K3,MAP4K4,MAPK1,MAPK10,MAPK11,MAPK14,MAPK3,MAPK8IP1,MAPK8IP3,MAPKAPK2,MAPKAPK3,MAPKAPK5,MARCO,MARVELD3,MBIP,MECOM,MEN1,MID1,MIF,MINK1,MOS,MST1R,MSTN,MUC20,MUL1,MYC,MYDGF,NBR1,NCF1,NDRG4,NDST1,NECAB2,NEK10,NENF,NF1,NF2,NGF,NLRP6,NOD1,NOTCH1,NOTCH2,NOX4,NPFFR2,NPTN,NPY5R,NQO2,NRG1,NRK,NRP1,NTF3,NTRK1,NTRK2,NTRK3,NUP62,OPRK1,OPRM1,OSM,P2RX7,P2RY1,PAFAH1B1,PAK1,PAK2,PAK3,PAK4,PAK5,PBK,PDCD10,PDE5A,PDE6H,PDE8A,PDGFA,PDGFB,PDGFC,PDGFD,PDGFRB,PEA15,PELI2,PER1,PHB,PHLPP1,PIK3CG,PIK3R2,PIK3R5,PIK3R6,PIN1,PINK1,PKHD1,PKN1,PLA2G1B,PLA2G2A,PLA2G5,PLCB1,PLCE1,PLCG1,PPEF2,PRDX1,PRKAA1,PRKCA,PRKCD,PRKCE,PRKCZ,PRKD2,PRKN,PRMT1,PRMT5,PROK1,PROK2,PSAP,PSCA,PSEN1,PSMD10,PTEN,PTK2B,PTPN1,PTPN11,PTPN22,PTPRJ,PTPRR,PYCARD,RAF1,RANBP9,RAP1A,RAP1B,RAP2A,RAPGEF1,RAPGEF2,RASGRP1,RASSF2,RB1CC1,REN,RGS14,RGS2,RGS3,RGS4,RIPK1,RIPK2,RIT2,RNF149,RNF41,ROBO1,ROR2,ROS1,RPS27A,RPS3,RPS6KA6,RRAS,RYK,S100A12,S100A7,SAA1,SASH1,SBK2,SDCBP,SEMA4C,SEMA7A,SERPINB3,SFRP1,SFRP2,SH3RF1,SHC1,SHC2,SIRT3,SLC30A10,SLC9A3R1,SMAD4,SMPD1,SOD1,SORBS3,SORL1,SOX2,SPAG9,SPRED1,SPRED2,SPRY1,SPRY2,SPRY4,SRC,SSTR4,STK24,STK26,STK38,STYX,SYK,SYNGAP1,SYNJ2BP,TAB1,TAB2,TAB3,TAOK1,TAOK2,TBC1D10C,TBX1,TDGF1,TEK,TENM1,TGFB1,TGFB2,TGFBR1,THBS1,THPO,TIAM1,TIMP2,TIMP3,TIRAP,TLR3,TLR4,TLR6,TLR9,TMEM189-UBE2V1,TNF,TNFAIP8L3,TNFRSF11A,TNFRSF19,TNFSF11,TNIK,TNIP1,TP73,TPD52L1,TRAF2,TRAF4,TRAF6,TRAF7,TREM2,TRIB1,TRIB2,TRIB3,TRIM5,TSG101,UBC,UBE2N,UCHL1,ULK4,UNC5CL,VANGL2,VEGFA,VRK2,VRK3,WNK2,WNT16,WNT5A,WNT7A,WNT7B,WWC1,XCL1,XCL2,XDH,ZC3H12A,ZNF622,ZNF675	TetrapodAncestor	300
GO.Biological.Process	GO:0043549	regulation.of.kinase.activity	1	1e-300	1e-300	1e-300	1.230728e+0	ABI1,ABL1,ACE,ACSL1,ACVR2B,ADAM8,ADAM9,ADAR,ADARB1,ADCY2,ADCY3,ADCY4,ADCY5,ADCY8,ADCYAP1,ADIPOQ,ADNP,ADORA1,ADORA2A,ADORA2B,ADRA2A,ADRA2B,ADRA2C,ADRB2,AFAP1L2,AGER,AGT,AIDA,AJUBA,AKAP13,AKT1S1,ALK,ALKAL1,ALS2,AMBRA1,ANGPT1,ANGPT4,ANKRD54,APC,APOE,APP,ARAF,ARRB1,ASPN,ATG14,ATP2B4,AVPI1,BAD,BAK1,BAX,BGN,BMP2,BMP4,BMP7,BRAF,C14orf166,C1QTNF2,C5,C8orf4,CAB39,CACUL1,CALM1,CALM2,CALM3,CAMK1,CAMK2N1,CAMK2N2,CAMKK1,CAMKK2,CARD10,CARD14,CARTPT,CASP3,CAV1,CAV3,CBL,CBLB,CBLC,CCDC88A,CCKBR,CCL19,CCL21,CCL5,CCNB1,CCNB3,CCND1,CCND2,CCND3,CCNE1,CCNE2,CCNG1,CCNH,CCNK,CCNL1,CCNL2,CCNT2,CCNYL1,CCR7,CD24,CD300A,CD40,CD74,CD81,CDC25A,CDC25B,CDC25C,CDC42,CDC6,CDK1,CDK20,CDK4,CDK5,CDK5R1,CDK5R2,CDK5RAP1,CDK7,CDKN1A,CDKN1B,CDKN1C,CDKN2A,CDKN2B,CDKN2C,CDKN2D,CDKN3,CEBPA,CEMIP,CENPE,CEP85,CHAD,CHI3L1,CHMP6,CHORDC1,CHP1,CHRNA3,CIB1,CISH,CKS1B,CKS2,CLU,CNPPD1,COPS8,COX11,CRK,CRKL,CSF1,CSF1R,CSK,CSNK2B,CSPG4,CXCL10,CXCR4,CYR61,DAB1,DAB2IP,DAXX,DBF4B,DBNDD2,DBNL,DCN,DDR2,DDX3X,DEPTOR,DGKQ,DIRAS3,DKK1,DLG1,DNAJA1,DRD2,DRD4,DSTYK,DTNBP1,DUS2,DUSP1,DUSP10,DUSP16,DUSP18,DUSP19,DUSP2,DUSP21,DUSP22,DUSP26,DUSP3,DUSP6,DUSP7,DUSP8,DUSP9,DVL1,DVL3,DYNAP,ECT2,EDN1,EDN3,EFNA1,EFNA5,EGF,EGFR,EGR1,EIF2AK2,ELP3,EMP2,ENSG00000278139,EPGN,EPHA1,EPHA4,EPHA8,EPHB2,EPO,ERBB2,ERCC6,EREG,ERN1,ERN2,ERP29,ERRFI1,ETAA1,EZH2,F2,F2R,FABP4,FAF1,FAM20A,FAM212A,FAM212B,FAM58A,FBXO7,FBXW7,FGD2,FGF1,FGF10,FGF13,FGF18,FGF2,FGFR1,FGFR1OP,FGFR3,FGR,FLRT1,FLRT2,FLRT3,FLT1,FOXA2,FRS2,FZD10,FZD4,FZD5,FZD8,GADD45A,GADD45B,GADD45G,GAS6,GBA,GCKR,GCN1,GGNBP2,GH1,GHR,GMFB,GMFG,GNAQ,GNG3,GP1BA,GPRC5A,GPRC5B,GPS1,GREM1,GRM4,GRM5,GSKIP,GSTP1,GTF2H1,H2AFY,HACD3,HEXIM1,HEXIM2,HGF,HGS,HHEX,HMGB1,HMGCR,HNRNPU,HRAS,HSP90AB1,HSPA2,HSPA5,HSPB1,HSPH1,HTR2A,HTR2B,IBTK,IFNG,IGF1,IGF1R,IGF2,IKBKG,IL12B,IL18,IL1B,IL23A,IL23R,IL6,INAVA,INCA1,INPP5K,INS,IQGAP1,IQGAP3,IRAK1,IRAK3,IRGM,IRS1,IRS2,ITGA1,JAK2,JTB,KARS,KAT2B,KITLG,KLF4,KRAS,LAMTOR2,LAMTOR3,LAT,LATS1,LATS2,LAX1,LCP2,LDB2,LEP,LMO4,LPAR1,LPAR3,LRP5,LRP6,LRP8,LRRC15,LRRC19,LRRC3,LRRC3C,LRRC4,LRRC4C,LRRC66,LRRK2,LRRTM1,LRRTM3,LRRTM4,LRTM1,LRTM2,LYN,MADD,MALT1,MAP2K2,MAP2K3,MAP2K4,MAP2K6,MAP2K7,MAP3K1,MAP3K10,MAP3K11,MAP3K12,MAP3K13,MAP3K14,MAP3K15,MAP3K19,MAP3K2,MAP3K21,MAP3K3,MAP3K4,MAP3K5,MAP3K6,MAP3K7,MAP3K7CL,MAP3K8,MAP3K9,MAP4K1,MAP4K3,MAP4K4,MAPK1,MAPK10,MAPK11,MAPK14,MAPK3,MAPK8IP1,MAPK8IP3,MAPKAP1,MAPKAPK2,MAPKAPK3,MAPKAPK5,MAPRE3,MAPT,MARK2,MAS1,MBIP,MCPH1,MEN1,MIF,MINK1,MLLT1,MLST8,MMD,MMD2,MOS,MRE11,MRNIP,MST1,MST1R,MSTN,MTCP1,MTOR,MUC20,MUL1,MVP,MYOCD,NAB2,NBN,NCF1,NCK1,NCK2,NCKAP1L,NEK1,NEK10,NEK4,NEURL1,NF1,NF2,NGF,NKX3-1,NLRC5,NOD1,NOX4,NPFFR2,NPM1,NPRL2,NRBF2,NRG1,NRG3,NRK,NTF3,NTRK1,NTRK3,NUP62,P2RX7,PAK1,PAK2,PAK3,PAK4,PAK5,PARK7,PARP16,PDCD10,PDE5A,PDE6H,PDGFA,PDGFB,PDGFC,PDGFD,PDGFRB,PDPK1,PEA15,PFKFB1,PFKFB2,PIFO,PIH1D1,PIK3CA,PIK3CG,PIK3IP1,PIK3R1,PIK3R2,PIK3R3,PIK3R5,PIK3R6,PINK1,PKD1,PKD2,PKIA,PKIB,PKIG,PKMYT1,PKN1,PLA2G1B,PLCE1,PLCG1,PLK1,PODN,PODNL1,PPEF2,PPM1E,PPM1F,PPP1R1A,PPP1R1C,PPP2R3C,PPP2R5A,PRDX3,PREX1,PRKAA1,PRKACA,PRKACG,PRKAG2,PRKAR1A,PRKAR1B,PRKAR2B,PRKCD,PRKCZ,PRKD1,PRKN,PRKRIP1,PRLR,PROK1,PROK2,PROX1,PRR5,PSEN1,PSMD10,PTEN,PTK2,PTK2B,PTPN1,PTPN11,PTPN22,PTPRJ,PYCARD,PYDC1,RAC2,RAD50,RAF1,RALB,RANBP2,RAP1A,RAP2B,RAP2C,RAPGEF1,RAPGEF2,RASGRP1,RASSF2,RB1,RBL1,RELN,RGCC,RGN,RGS14,RGS2,RGS3,RGS4,RICTOR,RIPK1,RIPK2,RIPK3,ROBO1,ROR2,RPS27A,RPS3,RPTOR,RTN4R,RTN4RL2,RUBCN,S100A12,SAA1,SASH1,SBK2,SDC4,SERPINB3,SESN2,SFN,SFRP1,SFRP2,SH3BP5,SHB,SHC1,SHC2,SIRT1,SLC11A1,SLC27A1,SLC9A3R1,SMCR8,SMG8,SMPD1,SMYD3,SNCA,SNX6,SNX9,SOCS1,SOCS2,SOCS3,SOCS4,SOCS5,SOCS6,SOCS7,SOD1,SORL1,SPAG9,SPDYA,SPDYE16,SPDYE4,SPDYE5,SPDYE6,SPRED1,SPRED2,SPRY1,SPRY2,SRC,SRCIN1,STAP1,STK24,STK26,STK38,STK4,STRADA,STRADB,SYK,TAB1,TAB2,TAB3,TAOK1,TAOK2,TARBP2,TCL1A,TCL1B,TDGF1,TEK,TELO2,TENM1,TESC,TGFB1,TGFB2,TGFBR1,TGFBR2,THBS1,THY1,TIAM1,TIGAR,TIRAP,TLR3,TLR4,TLR6,TLR9,TMEM189-UBE2V1,TNF,TNFAIP3,TNFAIP8L3,TNFRSF10A,TNFRSF10B,TNFRSF11A,TNFSF11,TNFSF15,TNIK,TOM1L1,TP73,TPD52L1,TPX2,TRAF2,TRAF4,TRAF6,TRAF7,TRIB1,TRIB2,TRIB3,TRPT1,TSC2,TSG101,TTN,TXN,UBASH3B,UBC,UBE2N,UCHL1,UCN,UNC119,UVRAG,UVSSA,VAC14,VANGL2,VAPB,VAV2,VAV3,VEGFA,VLDLR,VPS25,WARS,WDR81,WDR91,WEE2,WNK1,WNT11,WNT3A,WNT5A,WNT7B,WWTR1,XRCC5,XRCC6,YWHAG,ZFP91,ZFYVE28,ZNF16,ZNF622,ZNF675	TetrapodAncestor	300
GO.Biological.Process	GO:0045597	positive.regulation.of.cell.differentiation	1	1e-300	1e-300	1e-300	1.192001e+0	AAMDC,ABL1,ABL2,ACIN1,ACTR2,ACVR1B,ACVR2A,ACVR2B,ACVRL1,ADA,ADAM8,ADAMTS20,ADAMTS9,ADCYAP1,ADD1,ADGRB1,ADIG,ADIPOQ,ADIRF,ADNP,ADRA2B,ADRA2C,AGER,AGT,AGTR1,AHI1,AKAP6,ALKAL1,ALOX15B,ALX1,ANAPC2,ANKRD1,ANKRD27,ANKRD54,ANXA1,AP3D1,APOA1,APOB,APOE,AR,ARF1,ARHGAP35,ARHGDIA,ARHGEF2,ARHGEF7,ARNTL,ARPC2,ARRB2,ASCL1,ASPA,ASPM,ATOH1,ATOH8,ATP11C,ATP6AP1,ATP8A2,ATRAID,AURKA,AVIL,AXIN2,AXL,BAD,BAMBI,BCL2,BCL6,BCL9L,BDNF,BIN1,BLOC1S6,BMP10,BMP2,BMP4,BMP5,BMP6,BMP7,BMPR1A,BMPR1B,BMPR2,BOC,BRAF,BRINP1,BRINP2,BRINP3,BTC,BTG1,BTK,C1QBP,C21orf91,CA2,CALR,CAMK1,CAMK1D,CAMK2B,CAPRIN1,CAPRIN2,CARM1,CARMIL1,CASP8,CAV3,CBFA2T2,CCDC3,CCDC71L,CCL19,CCR1,CCR2,CD101,CD24,CD27,CD34,CD36,CD46,CD53,CD74,CD80,CD83,CD86,CDC42,CDH2,CDH4,CDH5,CDKL5,CDON,CEBPA,CEBPB,CEBPD,CFLAR,CIB1,CLCF1,CLDN5,CMKLR1,CNR1,CNTF,CNTN1,COBL,COL1A1,CPEB1,CPNE5,CPNE6,CRABP2,CRB2,CREB1,CREBL2,CRK,CRKL,CRX,CSF1,CSF3,CSNK1D,CSNK1E,CTGF,CTH,CTNNA1,CTNNA2,CTNNB1,CUL7,CUX1,CUX2,CX3CR1,CXCL9,CXCR4,CYFIP1,CYP26B1,CYP27B1,CYR61,DAB1,DAB2,DAB2IP,DCT,DDR2,DDX56,DISC1,DKK1,DKKL1,DLG5,DMRTA2,DMTN,DNM1L,DNM2,DNMT3B,DOCK5,DPYSL3,DRD2,DSCAM,DUOXA1,DUSP10,DVL1,DYNLT1,ECT2,EDN1,EDN3,EEF2K,EFNA5,EFNB2,EHD1,EHD2,ELL3,ENG,ENSG00000260272,EOMES,EPB41L5,EPHA3,EPHA4,EPHB2,EPO,ETS1,ETV5,EZH2,FADD,FAM129B,FAM20C,FAM210B,FBN2,FBXO31,FBXO38,FBXW8,FES,FEZ1,FEZF1,FGF18,FGF2,FGF20,FGFR1,FGG,FKBP1B,FLNA,FLOT1,FLT3LG,FMR1,FN1,FNDC5,FOS,FOXA1,FOXC1,FOXG1,FOXJ1,FOXN1,FOXO6,FOXP3,FZD3,GAS6,GATA2,GATA3,GATA4,GATA6,GCNT2,GDF2,GDF3,GDF5,GDF6,GDI1,GDNF,GDPD2,GDPD5,GFAP,GJC2,GLI2,GLI3,GLIPR2,GNAS,GOLGA4,GPC1,GPER1,GPR68,GPRC5B,GREM1,H2AFY,H2AFY2,HAMP,HAP1,HAS2,HAX1,HCLS1,HDAC2,HES1,HEYL,HGF,HIF1A,HIF1AN,HLX,HMG20B,HMGB1,HMGB2,HSF4,HSP90AB1,HSPA5,HTR2A,HTR2C,ID4,IFITM1,IFNG,IGF1,IHH,IL12A,IL12B,IL12RB1,IL13,IL15,IL17A,IL18,IL1B,IL1RAP,IL1RAPL1,IL1RL2,IL2,IL20,IL23A,IL23R,IL34,IL36B,IL4,IL5,IL6,IL6R,IL6ST,IL7,IL7R,INHBA,INPP5D,INS,INSM1,IQGAP1,ISG15,ISL1,ISLR2,IST1,ITGA3,ITPKA,ITPKB,ITSN2,JAG1,JAK2,JUN,JUNB,KALRN,KATNB1,KDF1,KDM1A,KDM4C,KIF20B,KITLG,KLF10,KLF5,L1CAM,LEF1,LEP,LGALS9,LHX1,LIF,LIG4,LILRB2,LILRB4,LIMK1,LIN28A,LLPH,LMO3,LMOD3,LOXL2,LPAR1,LPAR3,LPL,LRP5,LRP8,LRRC7,LTBP3,LTK,LYN,MACF1,MAG,MAGI2,MAML1,MAMSTR,MAN2A1,MAP1B,MAP3K5,MAPK11,MAPK14,MAPK6,MAPK9,MAPT,MARK2,MEDAG,MEF2A,MEF2C,MEGF8,MESP1,METRN,METRNL,MMD,MMD2,MMP14,MOB2,MORF4L2,MSR1,MSX2,MTOR,MUL1,MYADM,MYB,MYF6,MYLK3,MYOCD,MYOD1,MYOG,NBL1,NCK1,NCKAP1L,NCOA1,NCOA3,NDEL1,NDNF,NDRG4,NEDD4L,NEFL,NEGR1,NEK5,NELL1,NET1,NEURL1,NEUROD1,NEUROD4,NEUROG1,NEUROG3,NF2,NFATC2,NFKB1,NGF,NGFR,NIPBL,NKX2-5,NKX6-1,NLGN1,NME1,NME2,NOCT,NOTCH1,NPPC,NPTN,NRG1,NRP1,NTRK1,NTRK2,NTRK3,NUMB,NUMBL,OCSTAMP,OLFM1,OLFM2,OLFM4,OLIG2,OPA1,OPRM1,OVOL2,PAFAH1B1,PAK1,PAK3,PARP1,PAX2,PAX4,PAX8,PCID2,PCP4,PDE3A,PDE5A,PDLIM7,PDPN,PF4,PHOX2B,PIAS1,PIK3R6,PIN1,PKDCC,PLA2G10,PLA2G2A,PLAA,PLAG1,PLCB1,PLK5,PLPPR5,PLXNB1,PLXNB2,PLXNC1,PLXND1,PNP,POR,POU4F1,PPARD,PPARG,PPARGC1B,PPP1R13L,PPP2R3C,PPP2R5B,PRDM1,PRDM16,PREX1,PRKCA,PRKCH,PRKCI,PRKCZ,PRKD1,PRKN,PRMT1,PRMT5,PROC,PROM1,PROX1,PRPF19,PSEN1,PTCH1,PTCH2,PTEN,PTK2B,PTK7,PTN,PTPRD,PWP1,RAB21,RAB7B,RAC1,RAC3,RAG1,RAMP2,RANBP3L,RAP1A,RAPGEF1,RAPGEF2,RARA,RARB,RARRES2,RASAL1,RASGRP1,RB1,RBM4,RBPJ,RELA,RELN,RET,RFX3,RGCC,RGS14,RHEB,RIMS1,RIPK1,RIPK2,RIPOR2,RIT2,RND2,ROBO1,ROBO2,ROR2,RPS6KA1,RPS6KA3,RREB1,RRN3,RUFY3,RUNX1,RUNX2,S100A10,SART1,SASH3,SCARB2,SCGB3A1,SCIN,SCN1B,SDCBP,SEMA3A,SEMA3C,SEMA4D,SEMA5A,SEMA6A,SEMA7A,SERPINB3,SERPINE2,SERPINI1,SETD3,SETX,SF3A2,SFN,SFRP1,SFRP2,SFRP4,SHANK1,SHB,SHOX2,SIRT1,SIRT2,SKIL,SLC9B2,SLIT2,SLITRK1,SMAD2,SMAD4,SMAD5,SMAP1,SMO,SMURF1,SMYD1,SNAI1,SNAI2,SNW1,SOCS1,SOCS2,SOCS3,SOCS5,SOX10,SOX11,SOX17,SOX2,SOX5,SOX8,SOX9,SP7,SPAG9,SPEN,SPINT1,SRF,SRGAP2C,SRRT,STAR,STAT1,STK4,STMN2,SUCO,SULT2B1,SYK,SYT1,SYT17,SYT2,SYT4,TACSTD2,TAL1,TBX1,TBX5,TCF3,TCF4,TENM3,TENM4,TERT,TESC,TESPA1,TGFB1,TGFB1I1,TGFB2,TGFBR1,TGFBR2,TGIF2,THPO,THRA,TIAM1,TIMP2,TLE6,TLR2,TMEM100,TMEM106B,TMEM64,TNF,TNFRSF12A,TNFSF11,TNFSF14,TNFSF9,TP63,TP73,TPH1,TRAF6,TRAK1,TRIB1,TRIM32,TRIOBP,TRPC5,TRPC6,TRPM4,TSPO,TUBB2B,TWF2,TWIST1,UBE2V2,UFL1,UNC13A,UTS2,VDR,VEGFA,VEGFC,VLDLR,VNN1,VSTM2A,VWC2,VWC2L,WDFY2,WIF1,WNT10B,WNT3,WNT3A,WNT4,WNT5A,WNT7B,WNT9A,WWTR1,XBP1,XRCC2,XRCC5,ZAP70,ZBTB1,ZBTB16,ZBTB7C,ZC3H12A,ZEB1,ZFP36,ZFP36L1,ZFYVE27,ZHX3,ZMIZ1,ZMYND8,ZNF16,ZNF335,ZNF365,ZNF385A,ZNF488,ZNF609,ZNF703,ZNF804A	TetrapodAncestor	300
GO.Biological.Process	GO:0045785	positive.regulation.of.cell.adhesion	1	1e-300	1e-300	1e-300	1.346107e+0	ABI3BP,ABL1,ADA,ADAM8,ADAM9,ADGRG1,AGER,AGR2,AIF1,ALOX15,ANGPT1,ANK3,ANXA1,AP3D1,APOA1,ARHGEF7,ARL2,ARPC2,BAD,BAG4,BCL10,BCL6,BMP7,BRAF,BTLA,C1QBP,CALR,CARD11,CARMIL1,CAV1,CCDC80,CCDC88B,CCL19,CCL2,CCL21,CCL28,CCL5,CCR2,CCR7,CD1D,CD209,CD24,CD247,CD27,CD274,CD276,CD28,CD36,CD3D,CD3E,CD3G,CD44,CD46,CD47,CD5,CD55,CD59,CD6,CD74,CD80,CD83,CD86,CDC42,CDH13,CDK6,CHRD,CIB1,CITED2,CLECL1,COL16A1,COL26A1,COL8A1,CORO1A,CRK,CRKL,CSF1,CSK,CTLA4,CX3CL1,CXCL13,CYR61,CYTH3,DHPS,DISC1,DMP1,DMTN,DNAJA3,DNM2,DOCK5,DOCK8,DUSP10,DUSP26,EBI3,ECM2,EDIL3,EFNB1,EFNB2,EFNB3,EGFLAM,EMP2,EPB41L4B,EPB41L5,EPHA1,EPO,ERBB2,ETS1,FADD,FAM49B,FERMT1,FGG,FLCN,FLNA,FLOT1,FLOT2,FMN1,FN1,FOXA1,FOXA2,FOXC2,FOXF1,FOXP3,FRMD5,FSTL3,GATA3,GCNT2,GLI2,GLI3,GPAM,GRAP2,GRB2,HAS2,HAVCR2,HES1,HHLA2,HLX,HMGB1,HRG,HSD17B12,HSPH1,IBSP,ICOS,IFNG,IFT74,IGF1,IGF2,IGFBP2,IHH,IL10,IL12A,IL12B,IL12RB1,IL15,IL18,IL1B,IL1RL2,IL2,IL21,IL23A,IL23R,IL36B,IL4,IL6,IL6ST,IL7,IL7R,IQGAP1,ITGA2,ITGA3,ITGA4,ITGA5,ITGAV,ITPKB,JAK2,JAK3,KIF26B,KIFAP3,KIRREL1,KLRK1,LCK,LEP,LGALS1,LGALS9,LILRB2,LILRB4,LYN,MALT1,MAP3K14,MAP3K7,MAP3K8,MYADM,MYB,MYO10,NCK1,NCK2,NCKAP1L,NDNF,NET1,NINJ1,NPHS1,NPY2R,NR4A3,NRP1,OLFM4,PAK1,PAK2,PAK3,PDCD1,PDCD1LG2,PDPK1,PDPN,PIEZO1,PIK3CA,PIK3R1,PIK3R6,PLEKHA2,PLPP3,PNP,PODXL,PPM1F,PREX1,PRKCA,PRKCE,PRKCQ,PRKCZ,PRKD2,PRSS2,PTAFR,PTK2B,PTN,PTPN11,PTPN23,PTPRJ,PYCARD,RAC1,RAC3,RAG1,RARA,RASAL3,RASGRP1,RELL2,RET,RHOD,RIPK2,RNASE10,RPS3,RREB1,RSU1,S100A10,SAA1,SART1,SASH3,SDC4,SELENOK,SFRP1,SFRP2,SHB,SIRPG,SMAD7,SMOC2,SOCS1,SOCS5,SOX2,SPN,SPOCK2,SRC,STX3,STX4,SYK,TEK,TESPA1,TFE3,TFRC,TGFB1,TGFB2,TGFBR2,TGM2,THY1,TMIGD2,TNF,TNFRSF13C,TNFRSF14,TNFRSF18,TNFSF11,TNFSF13B,TNFSF14,TNFSF18,TNFSF9,TRAF2,TRAF6,TRIOBP,UTRN,VAV1,VAV3,VCAM1,VEGFA,VEGFC,VIT,VNN1,VTCN1,VTN,VWC2,WNT3A,WNT4,WNT5A,XBP1,XCL1,YES1,ZAP70,ZBTB1,ZBTB16,ZMIZ1,ZP3,ZP4	TetrapodAncestor	300
GO.Biological.Process	GO:0045859	regulation.of.protein.kinase.activity	1	1e-300	1e-300	1e-300	1.242888e+0	ABI1,ABL1,ACE,ACSL1,ACVR2B,ADAM8,ADAM9,ADAR,ADARB1,ADCY2,ADCY3,ADCY4,ADCY5,ADCY8,ADCYAP1,ADIPOQ,ADNP,ADORA1,ADORA2A,ADORA2B,ADRA2A,ADRA2B,ADRA2C,ADRB2,AFAP1L2,AGER,AGT,AIDA,AJUBA,AKAP13,AKT1S1,ALK,ALKAL1,ALS2,ANGPT1,ANGPT4,ANKRD54,APC,APOE,APP,ARAF,ARRB1,ASPN,ATP2B4,AVPI1,BAK1,BAX,BGN,BMP2,BMP4,BMP7,BRAF,C14orf166,C1QTNF2,C5,C8orf4,CAB39,CACUL1,CALM1,CALM2,CALM3,CAMK1,CAMK2N1,CAMK2N2,CAMKK1,CAMKK2,CARD10,CARD14,CARTPT,CASP3,CAV1,CAV3,CBL,CBLB,CBLC,CCDC88A,CCL19,CCL21,CCL5,CCNB1,CCNB3,CCND1,CCND2,CCND3,CCNE1,CCNE2,CCNG1,CCNH,CCNK,CCNL1,CCNL2,CCNT2,CCNYL1,CCR7,CD24,CD300A,CD40,CD74,CD81,CDC25A,CDC25B,CDC25C,CDC42,CDC6,CDK1,CDK20,CDK4,CDK5,CDK5R1,CDK5R2,CDK5RAP1,CDK7,CDKN1A,CDKN1B,CDKN1C,CDKN2A,CDKN2B,CDKN2C,CDKN2D,CDKN3,CEBPA,CEMIP,CENPE,CEP85,CHAD,CHI3L1,CHMP6,CHORDC1,CHP1,CHRNA3,CIB1,CISH,CKS1B,CKS2,CLU,CNPPD1,COPS8,CRK,CRKL,CSF1,CSF1R,CSK,CSNK2B,CSPG4,CXCL10,CXCR4,CYR61,DAB1,DAB2IP,DAXX,DBF4B,DBNDD2,DBNL,DCN,DDR2,DDX3X,DEPTOR,DGKQ,DIRAS3,DKK1,DLG1,DNAJA1,DRD2,DRD4,DTNBP1,DUS2,DUSP1,DUSP10,DUSP16,DUSP18,DUSP19,DUSP2,DUSP21,DUSP22,DUSP26,DUSP3,DUSP6,DUSP7,DUSP8,DUSP9,DVL1,DVL3,DYNAP,ECT2,EDN1,EDN3,EFNA1,EFNA5,EGF,EGFR,EGR1,EIF2AK2,ELP3,EMP2,EPGN,EPHA1,EPHA4,EPHB2,EPO,ERBB2,ERCC6,EREG,ERN1,ERN2,ERP29,ERRFI1,ETAA1,EZH2,F2R,FABP4,FAF1,FAM20A,FAM212A,FAM212B,FAM58A,FBXO7,FBXW7,FGD2,FGF1,FGF10,FGF13,FGF18,FGF2,FGFR1,FGFR1OP,FGR,FLRT1,FLRT2,FLRT3,FLT1,FRS2,FZD10,FZD4,FZD5,FZD8,GADD45A,GADD45B,GADD45G,GAS6,GBA,GCN1,GGNBP2,GH1,GHR,GMFB,GMFG,GNAQ,GNG3,GP1BA,GPRC5A,GPRC5B,GPS1,GREM1,GRM4,GRM5,GSKIP,GSTP1,GTF2H1,H2AFY,HACD3,HEXIM1,HEXIM2,HGF,HGS,HHEX,HMGB1,HMGCR,HRAS,HSP90AB1,HSPA2,HSPA5,HSPB1,HSPH1,HTR2A,HTR2B,IBTK,IFNG,IGF1,IGF1R,IGF2,IKBKG,IL12B,IL18,IL1B,IL23A,IL23R,IL6,INAVA,INCA1,INPP5K,INS,IQGAP1,IQGAP3,IRAK1,IRAK3,IRGM,ITGA1,JAK2,JTB,KARS,KAT2B,KITLG,KRAS,LAMTOR2,LAMTOR3,LAT,LATS1,LATS2,LAX1,LCP2,LEP,LPAR1,LPAR3,LRP5,LRP6,LRP8,LRRC15,LRRC19,LRRC3,LRRC3C,LRRC4,LRRC4C,LRRC66,LRRK2,LRRTM1,LRRTM3,LRRTM4,LRTM1,LRTM2,LYN,MADD,MALT1,MAP2K2,MAP2K3,MAP2K4,MAP2K6,MAP2K7,MAP3K1,MAP3K10,MAP3K11,MAP3K12,MAP3K13,MAP3K14,MAP3K15,MAP3K19,MAP3K2,MAP3K21,MAP3K3,MAP3K4,MAP3K5,MAP3K6,MAP3K7,MAP3K7CL,MAP3K8,MAP3K9,MAP4K1,MAP4K3,MAP4K4,MAPK1,MAPK10,MAPK11,MAPK14,MAPK3,MAPK8IP1,MAPK8IP3,MAPKAP1,MAPKAPK2,MAPKAPK3,MAPKAPK5,MAPRE3,MARK2,MAS1,MBIP,MEN1,MIF,MINK1,MLLT1,MLST8,MMD,MMD2,MOS,MRNIP,MST1,MST1R,MTCP1,MTOR,MUC20,MUL1,MVP,MYOCD,NAB2,NCF1,NCK1,NCK2,NCKAP1L,NEK1,NEK10,NEK4,NEURL1,NF1,NF2,NGF,NKX3-1,NOD1,NOX4,NPFFR2,NPM1,NRG1,NRG3,NRK,NTF3,NTRK1,NTRK3,NUP62,P2RX7,PAK1,PAK2,PAK3,PAK4,PAK5,PARK7,PARP16,PDCD10,PDE5A,PDE6H,PDGFA,PDGFB,PDGFC,PDGFD,PDGFRB,PDPK1,PEA15,PIH1D1,PIK3CA,PIK3CG,PIK3R5,PIK3R6,PINK1,PKD1,PKD2,PKIA,PKIB,PKIG,PKMYT1,PKN1,PLA2G1B,PLCE1,PLCG1,PLK1,PODN,PODNL1,PPEF2,PPM1E,PPM1F,PPP1R1A,PPP1R1C,PPP2R3C,PREX1,PRKAA1,PRKACA,PRKACG,PRKAG2,PRKAR1A,PRKAR1B,PRKAR2B,PRKCD,PRKCZ,PRKRIP1,PRLR,PROK1,PROK2,PROX1,PRR5,PSEN1,PSMD10,PTEN,PTK2,PTK2B,PTPN1,PTPN11,PTPN22,PTPRJ,PYCARD,PYDC1,RAC2,RAF1,RALB,RAP1A,RAP2B,RAP2C,RAPGEF1,RAPGEF2,RASGRP1,RASSF2,RB1,RELN,RGCC,RGN,RGS14,RGS2,RGS3,RGS4,RICTOR,RIPK1,RIPK2,RIPK3,ROBO1,ROR2,RPS27A,RPS3,RPTOR,RTN4R,RTN4RL2,S100A12,SAA1,SASH1,SBK2,SDC4,SERPINB3,SESN2,SFN,SFRP1,SFRP2,SH3BP5,SHB,SHC1,SHC2,SIRT1,SLC11A1,SLC27A1,SLC9A3R1,SMCR8,SMG8,SMPD1,SMYD3,SNCA,SNX6,SNX9,SOCS1,SOCS2,SOCS3,SOCS4,SOCS5,SOCS6,SOCS7,SOD1,SORL1,SPAG9,SPDYA,SPDYE16,SPDYE4,SPDYE5,SPDYE6,SPRED1,SPRED2,SPRY1,SPRY2,SRC,SRCIN1,STAP1,STK24,STK26,STK38,STK4,STRADA,STRADB,SYK,TAB1,TAB2,TAB3,TAOK1,TAOK2,TARBP2,TCL1A,TCL1B,TDGF1,TELO2,TENM1,TESC,TGFB1,TGFB2,TGFBR1,TGFBR2,THBS1,THY1,TIAM1,TIRAP,TLR3,TLR4,TLR6,TLR9,TMEM189-UBE2V1,TNF,TNFAIP3,TNFRSF10A,TNFRSF10B,TNFRSF11A,TNFSF11,TNFSF15,TNIK,TOM1L1,TP73,TPD52L1,TPX2,TRAF2,TRAF4,TRAF6,TRAF7,TRIB1,TRIB2,TRIB3,TRPT1,TSC2,TSG101,TTN,TXN,UBASH3B,UBC,UBE2N,UCHL1,UCN,UNC119,UVRAG,UVSSA,VANGL2,VAPB,VEGFA,VLDLR,VPS25,WARS,WEE2,WNK1,WNT11,WNT3A,WNT5A,WNT7B,WWTR1,XRCC5,XRCC6,YWHAG,ZFP91,ZFYVE28,ZNF675	TetrapodAncestor	300
GO.Biological.Process	GO:0048534	hematopoietic.or.lymphoid.organ.development	1	1e-300	1e-300	1e-300	1.313982e+0	ABI1,ABL1,ACE,ACIN1,ACTN1,ADA,ADAR,ADD1,ADGRG3,AGPAT5,AICDA,ANGPT1,ANLN,ANXA1,APP,ARHGEF7,ARID4A,ARMC6,ARTN,ASH2L,ASXL1,ATG5,ATM,ATP11C,ATPIF1,AXL,AZI2,BABAM1,BAK1,BARX1,BATF2,BATF3,BAX,BCL11B,BCL2,BCL2L11,BCL3,BCL6,BCR,BLNK,BMI1,BMP4,BMX,BRAF,BTK,CAMK4,CARD11,CASP3,CASP8,CASP9,CBFB,CCL19,CCR6,CCR7,CCR9,CD109,CD164,CD1D,CD28,CD34,CD3D,CD3E,CD74,CD79B,CD86,CD8A,CDC42,CDK13,CDK6,CDKN1C,CDKN2B,CEBPA,CEBPD,CEBPE,CEBPG,CHD2,CHD7,CIAPIN1,CIB1,CITED2,CLCF1,CLEC1B,CLEC4D,CLEC4E,CMTM7,COL24A1,CR2,CRIP2,CRKL,CSF1,CSF1R,CSF3,CTNNB1,CUL4A,CXCL13,CXCR5,DACT2,DCAF1,DCLRE1C,DHRS2,DHTKD1,DLL1,DLL4,DMTN,DNAJA3,DNASE2,DOCK10,DOCK11,DOCK2,DYRK3,EEF2,EFNA4,EGR1,EML1,EOMES,EP300,EPAS1,EPHA2,EPHB3,EPO,ERCC1,ERCC2,ESCO2,ETV6,F2RL1,FADD,FAM20C,FAM210B,FAS,FCER1G,FGF10,FGFR2,FLCN,FLI1,FLT3LG,FLVCR1,FOXE1,FOXL1,FOXN1,FOXP3,FST,FSTL3,FUT10,FUT7,FZD5,FZD7,FZD8,FZD9,G6PD,GAB2,GAS6,GATA2,GATA3,GLI3,GLO1,GLRX5,GON4L,GPC3,GPR18,GPR183,HAND2,HBZ,HCLS1,HDAC4,HDAC5,HDAC9,HEATR9,HES1,HHEX,HIF1A,HIPK1,HIPK2,HMGB1,HNF1A,HSPA9,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNB1,IFNE,IFNG,IFNK,IFNW1,IKZF1,IL10,IL12B,IL15,IL18R1,IL2,IL31RA,IL4,IL6,IL7,IL7R,INHA,INHBA,IRF1,IRF4,IRF8,ITFG2,ITGA4,ITGB1,ITK,ITM2A,ITPKB,JAG1,JAG2,JAGN1,JAK2,JAK3,JAM3,JARID2,JMJD6,JUN,JUNB,KAT6A,KAT8,KCNAB2,KDELR1,KIRREL3,KITLG,KLF1,KLF2,KLF4,KLF6,KMT2E,KRT75,L3MBTL1,L3MBTL3,LCK,LEF1,LEP,LEPR,LFNG,LGALS1,LIG4,LMO4,LRP5,LRRC17,LRRC8A,LTB,LTBR,LY6D,LYL1,LYN,MAD1L1,MAEA,MAFB,MALT1,MAPK1,MAPK14,MAPK3,MB,MECOM,MEF2C,MEIS1,MELK,MEOX1,MERTK,MFAP5,MFNG,MIXL1,MKNK2,MLF1,MMP9,MSH2,MYH9,MYO1E,NARFL,NBEAL2,NCKAP1L,NCOA6,NFAM1,NFKB2,NHEJ1,NKX2-3,NKX2-5,NKX3-2,NOTCH2,NOTCH4,NTRK1,OCSTAMP,ONECUT1,OSTM1,PAFAH1B1,PAPD4,PARP1,PATZ1,PBX1,PCID2,PDE1B,PDPN,PGM3,PICALM,PIK3CD,PIK3R1,PIP4K2A,PIR,PITX2,PKN1,PKNOX1,PLA2G2D,PLCG2,PLCL2,PLEK,PML,POLB,POLM,POU1F1,POU2F2,PPARG,PPP2R3C,PPP3CB,PRDX3,PREX1,PRKDC,PRKX,PSEN1,PSMB11,PTBP3,PTGER4,PTK2B,PTPN11,PTPN22,PTPRZ1,RAF1,RAG1,RAG2,RASGRP4,RB1,RBM47,RBPJ,RC3H1,RC3H2,RELB,REST,RET,RHAG,RIPK3,ROGDI,RORC,RPS14,RPS6,RRAS,RSAD2,RTKN2,RUNX1,RUNX2,SATB1,SBDS,SEMA4A,SERPINB12,SFRP1,SFRP2,SFXN1,SGPL1,SH2B3,SH3PXD2A,SHB,SIPA1L3,SIRT1,SLAMF6,SLC25A38,SLC40A1,SLC46A2,SLC7A6OS,SLC8A3,SMAD5,SMPD3,SNRK,SNX10,SOD1,SOX4,SP7,SPI1,SPN,SPNS2,SRC,SRF,SSBP3,STAT6,STK4,STON2,SYK,TAL1,TAZ,TBX1,TCF21,TCF3,TEK,TESC,TET2,TFRC,TGFB1,TGFB2,TGFBR1,TGFBR2,THEMIS,THOC5,THPO,THRA,TIPARP,TIRAP,TLR2,TMEM91,TMOD3,TNF,TNFRSF11A,TNFRSF13B,TNFSF11,TNFSF8,TOP2A,TPD52,TPO,TRAF6,TREM2,TRPM2,TSPAN2,TTC7A,TYR,TYRO3,VAV1,VCAM1,VEGFA,VPS33B,WASF2,WDR1,WDR7,WDR78,WNT1,WNT10B,WNT3A,WNT4,WNT5A,XRCC5,ZAP70,ZBTB1,ZBTB16,ZBTB24,ZFAT,ZFP36L1,ZFP36L2,ZFPM1,ZNF160,ZNF385A,ZNF683,ZNF784	TetrapodAncestor	300
GO.Biological.Process	GO:0050863	regulation.of.T.cell.activation	1	1e-300	1e-300	1e-300	1.414414e+0	ABL1,ADA,ADAM8,ADORA2A,AGER,AIF1,ANXA1,AP3D1,ARG1,ARG2,BAD,BCL10,BCL6,BMP4,BRAF,BTLA,CAMK4,CARD11,CASP3,CAV1,CBFB,CCDC88B,CCL19,CCL2,CCL21,CCL5,CCR2,CCR7,CD1D,CD2,CD209,CD24,CD247,CD27,CD274,CD276,CD28,CD300A,CD3D,CD3E,CD3G,CD46,CD47,CD5,CD55,CD59,CD6,CD74,CD80,CD83,CD86,CDC42,CEBPB,CLC,CLEC4G,CLECL1,CORO1A,CR1,CSK,CTLA4,CTNNB1,CYP26B1,DHPS,DLG1,DLG5,DNAJA3,DOCK8,DROSHA,DTX1,DUSP10,DUSP22,DUSP3,EBI3,EFNB1,EFNB2,EFNB3,EPO,ERBB2,FADD,FAM49B,FANCA,FLOT2,FOXJ1,FOXN1,FOXP3,GATA3,GLI2,GLI3,GNRH1,GPAM,GPNMB,GRAP2,GRB2,GSN,HAVCR2,HES1,HHLA2,HLX,HMGB1,HSPH1,ICOS,IDO1,IFNA2,IFNB1,IFNG,IFNL1,IFNL2,IFNL3,IGF1,IGF2,IGFBP2,IHH,IL10,IL12A,IL12B,IL12RB1,IL15,IL18,IL1B,IL1RL2,IL2,IL20RB,IL21,IL23A,IL23R,IL27,IL36B,IL4,IL6,IL6ST,IL7,IL7R,IRF1,IRF4,ITCH,ITPKB,JAK3,KIRREL1,KLRK1,LAT,LAX1,LCK,LEP,LGALS1,LGALS3,LGALS9,LILRB2,LILRB4,LOXL3,LRRC32,LYN,MAD1L1,MALT1,MAP3K14,MAP3K7,MAP3K8,METTL3,MYB,NCK1,NCK2,NCKAP1L,NDFIP1,NFATC2,NFKBID,NPHS1,PAG1,PAK1,PAK2,PAK3,PAWR,PDCD1,PDCD1LG2,PDE5A,PDPK1,PELI1,PIK3CA,PIK3R1,PIK3R6,PLA2G2D,PLA2G2F,PNP,PRDM1,PRELID1,PRKAR1A,PRKCQ,PRKCZ,PTPN11,PTPN22,PYCARD,RAC1,RAC2,RAG1,RARA,RASAL3,RASGRP1,RC3H1,RIPK2,RIPK3,RIPOR2,RPS3,RUNX1,SART1,SASH3,SCGB1A1,SDC4,SELENOK,SHB,SIRPG,SIT1,SLC46A2,SMAD7,SOCS1,SOCS5,SOCS6,SOD1,SOS1,SOX13,SPINK5,SPN,SRC,SYK,TARM1,TESPA1,TFRC,TGFB1,TGFBR2,THY1,TIGIT,TMEM131L,TMIGD2,TNFAIP8L2,TNFRSF13C,TNFRSF14,TNFRSF18,TNFRSF21,TNFSF11,TNFSF13B,TNFSF14,TNFSF18,TNFSF9,TRAF2,TRAF6,VAV1,VCAM1,VNN1,VSIG4,VTCN1,XBP1,XCL1,YES1,ZAP70,ZBTB1,ZBTB16,ZBTB7B,ZC3H8,ZEB1,ZMIZ1,ZNF683,ZP3,ZP4	TetrapodAncestor	300
GO.Biological.Process	GO:0050865	regulation.of.cell.activation	1	1e-300	1e-300	1e-300	1.335135e+0	ABAT,ABL1,ABR,ADA,ADAM8,ADAMTS18,ADGRE2,ADGRF5,ADORA2A,ADORA2B,AGER,AHR,AIF1,ANXA1,AP1G1,AP3D1,APLF,APOE,APP,ARG1,ARG2,ATAD5,ATM,ATP11C,AXL,BAD,BANK1,BCL10,BCL2,BCL6,BCR,BMP4,BPI,BRAF,BST1,BTK,BTLA,C12orf4,C1QTNF1,CAMK4,CARD11,CASP3,CAV1,CBFB,CCDC88B,CCL19,CCL2,CCL21,CCL5,CCR2,CCR7,CD1D,CD2,CD209,CD226,CD24,CD247,CD27,CD274,CD276,CD28,CD300A,CD300LF,CD320,CD38,CD3D,CD3E,CD3G,CD40,CD46,CD47,CD5,CD55,CD59,CD6,CD74,CD80,CD81,CD83,CD86,CD9,CDC42,CDKN1A,CEBPB,CHRNB2,CLC,CLCF1,CLEC4G,CLECL1,CNR1,CNR2,CORO1A,CR1,CSK,CTGF,CTLA4,CTNNB1,CYGB,CYP26B1,DHPS,DLG1,DLG5,DMTN,DNAJA3,DOCK8,DROSHA,DTX1,DUSP10,DUSP22,DUSP3,EBI3,EFNB1,EFNB2,EFNB3,EPO,ERBB2,EXOSC3,EXOSC6,F2,F2RL1,FADD,FAM19A3,FAM49B,FANCA,FAS,FBXO7,FCER1G,FER,FES,FGF10,FGG,FGR,FLOT2,FLT3LG,FOXF1,FOXJ1,FOXN1,FOXP3,GAB2,GAL,GAS6,GATA2,GATA3,GLI2,GLI3,GNRH1,GPAM,GPER1,GPNMB,GPR183,GRAP2,GRB2,GSN,HAVCR2,HES1,HHLA2,HLX,HMGB1,HMGB3,HMOX1,HRG,HSPH1,ICOS,IDO1,IFNA2,IFNB1,IFNG,IFNL1,IFNL2,IFNL3,IGF1,IGF2,IGFBP2,IGLL1,IGLL5,IHH,IKZF3,IL10,IL12A,IL12B,IL12RB1,IL13,IL13RA2,IL15,IL18,IL1B,IL1RL1,IL1RL2,IL2,IL20RB,IL21,IL23A,IL23R,IL27,IL27RA,IL31RA,IL33,IL36B,IL4,IL5,IL6,IL6ST,IL7,IL7R,INHA,INHBA,INPP5D,IRF1,IRF4,IRS2,ITCH,ITGAM,ITGB2,ITPKB,JAK2,JAK3,KARS,KIRREL1,KLRK1,LAT,LAX1,LBP,LCK,LDLR,LEP,LGALS1,LGALS3,LGALS9,LILRB2,LILRB4,LMO4,LOXL3,LRRC32,LST1,LYN,MAD1L1,MALT1,MAP3K14,MAP3K7,MAP3K8,MEF2C,MERTK,METTL3,MIF,MILR1,MLH1,MMP14,MSH2,MSH6,MYB,MYO18A,MZB1,NCK1,NCK2,NCKAP1L,NDFIP1,NECTIN2,NFAM1,NFATC2,NFKBID,NOS3,NPHS1,NR1H3,NR4A3,NSD2,PAG1,PAK1,PAK2,PAK3,PAWR,PAXIP1,PCID2,PDCD1,PDCD1LG2,PDE5A,PDGFA,PDGFB,PDGFRB,PDPK1,PDPN,PELI1,PGLYRP1,PGLYRP2,PGLYRP3,PIK3CA,PIK3R1,PIK3R6,PKN1,PLA2G10,PLA2G2D,PLA2G2F,PLEK,PLSCR1,PNP,PPP2R3C,PRAM1,PRDM1,PRELID1,PRKAR1A,PRKCA,PRKCD,PRKCQ,PRKCZ,PRKG1,PTAFR,PTPN11,PTPN22,PYCARD,RAC1,RAC2,RAG1,RARA,RASAL3,RASGRP1,RC3H1,RHBDD3,RIF1,RIPK2,RIPK3,RIPOR2,RNF41,RPS3,RPS6KA1,RUNX1,SAMSN1,SART1,SASH3,SCGB1A1,SDC4,SELENOK,SELP,SERPINE2,SFRP1,SHB,SHPK,SIRPG,SIT1,SLA2,SLC39A10,SLC46A2,SMAD7,SNCA,SNX4,SOCS1,SOCS5,SOCS6,SOD1,SOS1,SOX11,SOX13,SOX15,SPACA3,SPINK5,SPN,SRC,STAP1,STAT6,STX4,STXBP1,STXBP2,STYK1,SYK,TAC1,TARM1,TBC1D10C,TEC,TESPA1,TFRC,TGFB1,TGFBR2,THBD,THBS1,THOC1,THY1,TICAM1,TIGIT,TIRAP,TLR4,TLR6,TLR9,TMEM131L,TMIGD2,TNFAIP3,TNFAIP8L2,TNFRSF13B,TNFRSF13C,TNFRSF14,TNFRSF18,TNFRSF21,TNFRSF4,TNFSF11,TNFSF13,TNFSF13B,TNFSF14,TNFSF18,TNFSF9,TNIP2,TRAF2,TRAF6,TSPAN32,TXK,TYRO3,UBASH3B,UNG,VAMP8,VAV1,VAV3,VCAM1,VNN1,VPS33B,VSIG4,VTCN1,WNT3A,WNT5A,XBP1,XCL1,YES1,ZAP70,ZBTB1,ZBTB16,ZBTB7B,ZC3H12A,ZC3H8,ZEB1,ZFP36L1,ZFP36L2,ZMIZ1,ZNF335,ZNF683,ZP3,ZP4	TetrapodAncestor	300
GO.Biological.Process	GO:0051249	regulation.of.lymphocyte.activation	1	1e-300	1e-300	1e-300	1.356750e+0	ABL1,ADA,ADAM8,ADORA2A,AGER,AHR,AIF1,ANXA1,AP1G1,AP3D1,APLF,ARG1,ARG2,ATAD5,ATM,ATP11C,AXL,BAD,BANK1,BCL10,BCL2,BCL6,BMP4,BRAF,BST1,BTK,BTLA,CAMK4,CARD11,CASP3,CAV1,CBFB,CCDC88B,CCL19,CCL2,CCL21,CCL5,CCR2,CCR7,CD1D,CD2,CD209,CD24,CD247,CD27,CD274,CD276,CD28,CD300A,CD320,CD38,CD3D,CD3E,CD3G,CD40,CD46,CD47,CD5,CD55,CD59,CD6,CD74,CD80,CD81,CD83,CD86,CDC42,CDKN1A,CEBPB,CHRNB2,CLC,CLCF1,CLEC4G,CLECL1,CORO1A,CR1,CSK,CTLA4,CTNNB1,CYP26B1,DHPS,DLG1,DLG5,DNAJA3,DOCK8,DROSHA,DTX1,DUSP10,DUSP22,DUSP3,EBI3,EFNB1,EFNB2,EFNB3,EPO,ERBB2,EXOSC3,EXOSC6,FADD,FAM49B,FANCA,FAS,FBXO7,FGF10,FLOT2,FLT3LG,FOXJ1,FOXN1,FOXP3,GAL,GAS6,GATA3,GLI2,GLI3,GNRH1,GPAM,GPNMB,GPR183,GRAP2,GRB2,GSN,HAVCR2,HES1,HHLA2,HLX,HMGB1,HMGB3,HSPH1,ICOS,IDO1,IFNA2,IFNB1,IFNG,IFNL1,IFNL2,IFNL3,IGF1,IGF2,IGFBP2,IGLL1,IGLL5,IHH,IKZF3,IL10,IL12A,IL12B,IL12RB1,IL13,IL15,IL18,IL1B,IL1RL2,IL2,IL20RB,IL21,IL23A,IL23R,IL27,IL27RA,IL36B,IL4,IL5,IL6,IL6ST,IL7,IL7R,INHA,INHBA,INPP5D,IRF1,IRF4,IRS2,ITCH,ITPKB,JAK3,KIRREL1,KLRK1,LAT,LAX1,LCK,LEP,LGALS1,LGALS3,LGALS9,LILRB2,LILRB4,LOXL3,LRRC32,LST1,LYN,MAD1L1,MALT1,MAP3K14,MAP3K7,MAP3K8,MEF2C,MERTK,METTL3,MIF,MLH1,MMP14,MSH2,MSH6,MYB,MZB1,NCK1,NCK2,NCKAP1L,NDFIP1,NFAM1,NFATC2,NFKBID,NPHS1,NSD2,PAG1,PAK1,PAK2,PAK3,PAWR,PAXIP1,PCID2,PDCD1,PDCD1LG2,PDE5A,PDPK1,PELI1,PGLYRP1,PGLYRP2,PGLYRP3,PIK3CA,PIK3R1,PIK3R6,PKN1,PLA2G2D,PLA2G2F,PNP,PPP2R3C,PRDM1,PRELID1,PRKAR1A,PRKCQ,PRKCZ,PTPN11,PTPN22,PYCARD,RAC1,RAC2,RAG1,RARA,RASAL3,RASGRP1,RC3H1,RHBDD3,RIF1,RIPK2,RIPK3,RIPOR2,RNF41,RPS3,RUNX1,SAMSN1,SART1,SASH3,SCGB1A1,SDC4,SELENOK,SFRP1,SHB,SIRPG,SIT1,SLA2,SLC39A10,SLC46A2,SMAD7,SOCS1,SOCS5,SOCS6,SOD1,SOS1,SOX11,SOX13,SPINK5,SPN,SRC,STAT6,SYK,TAC1,TARM1,TBC1D10C,TESPA1,TFRC,TGFB1,TGFBR2,THOC1,THY1,TICAM1,TIGIT,TIRAP,TLR4,TLR9,TMEM131L,TMIGD2,TNFAIP3,TNFAIP8L2,TNFRSF13B,TNFRSF13C,TNFRSF14,TNFRSF18,TNFRSF21,TNFRSF4,TNFSF11,TNFSF13,TNFSF13B,TNFSF14,TNFSF18,TNFSF9,TNIP2,TRAF2,TRAF6,TYRO3,UNG,VAV1,VAV3,VCAM1,VNN1,VSIG4,VTCN1,WNT3A,XBP1,XCL1,YES1,ZAP70,ZBTB1,ZBTB16,ZBTB7B,ZC3H8,ZEB1,ZFP36L1,ZFP36L2,ZMIZ1,ZNF335,ZNF683,ZP3,ZP4	TetrapodAncestor	300
GO.Biological.Process	GO:0051270	regulation.of.cellular.component.movement	1	1e-300	1e-300	1e-300	1.210759e+0	AAMP,ABHD2,ABHD6,ABI3,ABL1,ABL2,ABR,ACE,ACKR3,ACTN1,ACTN4,ACVR1B,ACVRL1,ADA,ADAM15,ADAM8,ADAM9,ADAMTS9,ADARB1,ADGRA2,ADGRB1,ADGRG1,ADGRG3,ADIPOQ,ADIPOR1,ADORA1,ADORA3,ADRA2A,AGT,AGTR2,AIF1,AJUBA,AKT2,ALOX15B,AMOT,AMOTL1,ANGPT1,ANGPT2,ANGPT4,ANK2,ANO6,ANXA1,ANXA3,AP1AR,APC,APEX1,APOD,APOE,APOH,APP,AQP1,ARAP1,ARAP3,ARHGAP18,ARHGAP4,ARHGDIB,ARHGEF2,ARHGEF39,ARHGEF7,ARID2,ARPIN,ATOH8,ATP1A1,ATP1A2,ATP5A1,ATP8A1,B4GALT1,BAG4,BBS4,BCAR1,BCAS3,BCL2,BCL6,BCR,BDKRB1,BMP10,BMP2,BMP4,BMP5,BMP7,BMPER,BMPR1A,BMPR2,BRAF,BST1,BST2,BTC,C16orf45,C1QBP,C21orf59,C3AR1,C5,C5orf30,CACNA1C,CALR,CAMK1D,CAMK2D,CAMSAP3,CAPN7,CARMIL1,CARMIL2,CATSPER1,CAV1,CAV3,CBLL1,CCBE1,CCDC125,CCDC40,CCDC65,CCL1,CCL11,CCL19,CCL2,CCL21,CCL28,CCL3,CCL4,CCL5,CCL7,CCL8,CCR1,CCR2,CCR6,CCR7,CD274,CD300A,CD40,CD74,CD81,CDH13,CDK5,CDK6,CDKN1B,CEMIP,CERS2,CFAP20,CGA,CHRD,CIB1,CITED2,CLASP1,CLASP2,CMKLR1,COL18A1,COL1A1,COL3A1,CORO1A,CORO1B,CPEB1,CPNE3,CREB3,CRK,CSF1,CSF1R,CSNK2B,CTNNA1,CTNNA3,CTSH,CX3CL1,CX3CR1,CXCL1,CXCL10,CXCL11,CXCL13,CXCL14,CXCL16,CXCL2,CXCL3,CXCL5,CXCL6,CXCL8,CXCL9,CXCR3,CYGB,CYP19A1,CYP1B1,CYR61,DAB2,DAB2IP,DACH1,DAPK2,DAPK3,DCN,DDR2,DDRGK1,DDT,DDX58,DIAPH1,DLC1,DLG1,DLG5,DLL4,DMTN,DNAAF1,DOCK10,DOCK4,DOCK5,DOCK8,DPEP1,DPYSL3,DRD1,DRD2,DSC2,DSCAM,DSG2,DSP,DUSP10,EDN1,EDN2,EDN3,EFNA1,EGF,EGFR,ELP3,EMP2,ENG,ENPP2,ENSG00000259753,ENSG00000260272,EPB41L4B,EPB41L5,EPCAM,EPHA1,EPHA2,EPPIN,EPPIN-WFDC6,ERBB2,ERBB4,EREG,ETS1,EVL,F10,F2R,F2RL1,F3,F7,FADD,FAM60A,FAM83H,FAM89B,FBLN1,FBXO31,FER,FERMT3,FES,FGF1,FGF10,FGF13,FGF16,FGF18,FGF2,FGF4,FGF7,FGFR1,FGFR1OP,FGR,FLCN,FLNA,FLRT2,FLT1,FLT4,FN1,FOXC2,FOXF1,FOXO4,FRMD5,FSHB,FUZ,GAB1,GAS6,GATA3,GATA4,GCNT2,GDF2,GLIPR2,GNA12,GNA13,GNRH1,GPER1,GPLD1,GPNMB,GPR18,GPR183,GPSM3,GRB7,GREM1,GSTP1,GTSE1,HACE1,HAP1,HAS2,HBEGF,HCN4,HDAC4,HDAC5,HDAC7,HDAC9,HGF,HIF1A,HMCN2,HMGB1,HMOX1,HRAS,HRG,HSPA5,HSPB1,IDH2,IFITM1,IFNG,IGBP1,IGF1,IGF1R,IGFBP5,IGSF10,IL12A,IL1A,IL1B,IL1R1,IL23A,IL24,IL33,IL4,IL6,IL6R,INS,INSL3,INSM1,IQCF1,IQGAP1,IRS2,ITGA2,ITGA2B,ITGA3,ITGA4,ITGA5,ITGAV,JAG1,JAG2,JAK2,JAM3,JCAD,JUN,JUP,KANK1,KARS,KCNE3,KCNJ2,KIF20B,KITLG,KLF4,KLRK1,KRIT1,KRT16,LAMA1,LAMA2,LAMA3,LAMA4,LAMA5,LAMB1,LBP,LDB2,LDLRAD4,LEF1,LGALS3,LGALS9,LGR6,LMNA,LMO4,LPAR1,LRCH1,LRIG2,LRP1,LRRC15,LYN,MACF1,MADCAM1,MAGI2,MAPK1,MAPK14,MAPK3,MAPRE1,MARVELD3,MCAM,MCC,MCTP1,MDM2,MEGF8,MEMO1,MEOX2,MET,MIA3,MIEN1,MIF,MIIP,MINK1,MKKS,MMP10,MMP14,MMP28,MMP9,MMRN2,MOSPD2,MPP1,MSN,MTA2,MTOR,MYADM,MYBPC3,MYLK,MYLK2,MYO1C,MYOCD,MYPN,MYSM1,NAV3,NBL1,NCK1,NCKAP1L,NDRG4,NEFH,NF1,NF2,NIPBL,NISCH,NKX6-1,NOG,NOS1AP,NOTCH1,NOV,NOX4,NRG1,NRG2,NRG3,NRG4,NRP1,NRP2,NTF3,NTRK3,NUMB,ONECUT1,P2RX4,P2RY6,PADI2,PAK1,PAK3,PARD6B,PBLD,PDCD10,PDCD6,PDE4B,PDE4D,PDGFA,PDGFB,PDGFC,PDGFD,PDGFRB,PDPK1,PDPN,PF4,PF4V1,PFN1,PFN2,PGAM4,PHLDA2,PHLDB2,PHPT1,PIK3CD,PIK3R1,PIN1,PITX2,PKHD1,PKN1,PKP2,PLA2G7,PLAA,PLAU,PLCB1,PLCG1,PLET1,PLN,PLPP3,PLVAP,PLXNA1,PLXNA2,PLXNA3,PLXNA4,PLXNB2,PLXND1,PODN,PODXL,PPARD,PPARG,PPARGC1A,PPBP,PPM1F,PRCP,PREX1,PRKCA,PRKCE,PRKD1,PRKD2,PRKX,PROX1,PRR5L,PTAFR,PTEN,PTGER4,PTK2,PTK2B,PTN,PTP4A1,PTPN23,PTPRG,PTPRJ,PTPRK,PTPRM,PTPRO,PTPRR,PTPRU,PYCARD,RAB25,RAC1,RAC2,RAF1,RAP2A,RAP2B,RAP2C,RAPGEF2,RARRES2,RCC2,RDX,RECK,RELN,RET,RETN,RFFL,RGCC,RGN,RHOD,RIPK3,RIPOR1,RIPOR2,RNASE10,RNF20,RNF207,RNF41,ROBO1,ROBO4,ROCK2,ROR2,RRAS,RRAS2,RREB1,RTN4,RUFY3,RYR2,S100A14,S100A7,S1PR1,SASH1,SCAI,SCARB1,SCN5A,SCRT1,SCRT2,SDC4,SDCBP,SELENOK,SELP,SEMA3A,SEMA3C,SEMA4A,SEMA4D,SEMA5A,SEMA6A,SEMA6D,SEMG1,SEMG2,SERPINB3,SERPINE2,SFRP1,SFRP2,SGK1,SH3BP1,SLC26A5,SLC8A1,SLC8B1,SLC9A3R1,SLIT2,SLURP1,SMAD7,SMURF2,SNAI1,SNAI2,SOD2,SORL1,SOX14,SOX9,SP100,SPAG9,SPATA13,SPHK1,SPOCK2,SPOCK3,SPRED1,SPRY2,SRC,SRCIN1,SRF,SRGAP1,SRGAP2,SRGAP2B,SRGAP2C,SRGAP3,SRI,SRPX2,SST,STAP1,STARD13,STC1,STK24,STK26,STMN1,STRAP,STX4,SUMO1,SUN2,SYDE1,SYNE2,SYNJ2BP,TAC1,TAC4,TACR3,TACSTD2,TBCCD1,TBX5,TDGF1,TEK,TERT,TGFB1,TGFB2,TGFBR1,TGFBR2,THBS1,THBS4,THY1,TIAM1,TIE1,TIMP1,TIRAP,TMEFF2,TMIGD1,TMIGD3,TMSB4Y,TNF,TNFAIP6,TNFRSF14,TNFRSF18,TNFSF14,TNFSF18,TNNC1,TNNT2,TP53INP1,TRIB1,TRIM32,TRIM58,TRIP6,TRPM4,TUBB2B,TWIST1,ULK4,UNC5C,UNC5D,UTS2,VASH1,VCL,VEGFA,VEGFB,VEGFC,VEGFD,VIL1,VTN,WNT11,WNT3,WNT3A,WNT4,WNT5A,WNT7A,XBP1,XCL1,ZC3H12A,ZMYND8,ZNF580,ZNF609,ZNF703,ZP3	TetrapodAncestor	300
GO.Biological.Process	GO:0051338	regulation.of.transferase.activity	1	1e-300	1e-300	1e-300	1.216335e+0	ABI1,ABL1,ACD,ACE,ACSL1,ACVR2B,ADAM8,ADAM9,ADAR,ADARB1,ADCY2,ADCY3,ADCY4,ADCY5,ADCY8,ADCYAP1,ADIPOQ,ADNP,ADORA1,ADORA2A,ADORA2B,ADRA2A,ADRA2B,ADRA2C,ADRB2,AFAP1L2,AGER,AGT,AIDA,AJUBA,AKAP13,AKT1S1,ALK,ALKAL1,ALS2,AMBRA1,ANAPC1,ANAPC11,ANAPC16,ANAPC2,ANAPC4,ANAPC5,ANGPT1,ANGPT4,ANKRD54,APC,APOE,APP,ARAF,ARRB1,ARRDC3,ARRDC4,ASPN,ATG14,ATP2B4,AURKB,AVPI1,BAD,BAK1,BAX,BGN,BMI1,BMP2,BMP4,BMP7,BRAF,BTRC,C14orf166,C1QTNF2,C5,C8orf4,CAB39,CACUL1,CALM1,CALM2,CALM3,CAMK1,CAMK2N1,CAMK2N2,CAMKK1,CAMKK2,CARD10,CARD14,CARTPT,CASP3,CAV1,CAV3,CBL,CBLB,CBLC,CCDC88A,CCKBR,CCL19,CCL21,CCL5,CCNB1,CCNB3,CCND1,CCND2,CCND3,CCNE1,CCNE2,CCNG1,CCNH,CCNK,CCNL1,CCNL2,CCNT2,CCNYL1,CCR7,CCT2,CCT4,CD24,CD300A,CD40,CD74,CD81,CDC14B,CDC16,CDC20,CDC20B,CDC23,CDC25A,CDC25B,CDC25C,CDC26,CDC27,CDC42,CDC6,CDK1,CDK2,CDK20,CDK4,CDK5,CDK5R1,CDK5R2,CDK5RAP1,CDK7,CDKN1A,CDKN1B,CDKN1C,CDKN2A,CDKN2B,CDKN2C,CDKN2D,CDKN3,CEBPA,CEMIP,CENPE,CEP85,CERS1,CHAD,CHCHD10,CHI3L1,CHMP6,CHORDC1,CHP1,CHRNA3,CHTF18,CIB1,CISH,CKS1B,CKS2,CLU,CNPPD1,COPS8,COX11,CRK,CRKL,CSF1,CSF1R,CSK,CSNK2B,CSPG4,CTNNB1,CUL1,CXCL10,CXCR4,CYR61,DAB1,DAB2IP,DAXX,DBF4B,DBNDD2,DBNL,DCN,DCUN1D1,DCUN1D3,DCUN1D4,DCUN1D5,DDR2,DDX3X,DEPTOR,DGKQ,DIRAS3,DKC1,DKK1,DLG1,DNAJA1,DRD2,DRD4,DSCC1,DSTYK,DTNBP1,DTX3L,DUS2,DUSP1,DUSP10,DUSP16,DUSP18,DUSP19,DUSP2,DUSP21,DUSP22,DUSP26,DUSP3,DUSP6,DUSP7,DUSP8,DUSP9,DVL1,DVL3,DYNAP,ECT2,EDN1,EDN3,EFNA1,EFNA5,EGF,EGFR,EGR1,EIF2AK2,EIF4A2,ELP3,EMP2,ENSG00000278139,EPGN,EPHA1,EPHA4,EPHA8,EPHB2,EPM2AIP1,EPO,ERBB2,ERCC6,EREG,ERN1,ERN2,ERP29,ERRFI1,ETAA1,EZH2,F2,F2R,FABP4,FAF1,FAM20A,FAM212A,FAM212B,FAM58A,FBXO5,FBXO7,FBXW7,FEM1A,FEM1B,FGD2,FGF1,FGF10,FGF13,FGF18,FGF2,FGFR1,FGFR1OP,FGFR3,FGR,FLRT1,FLRT2,FLRT3,FLT1,FOXA2,FRS2,FZD10,FZD4,FZD5,FZD8,FZR1,GADD45A,GADD45B,GADD45G,GAS6,GBA,GCKR,GCN1,GGNBP2,GH1,GHR,GMFB,GMFG,GNAQ,GNG3,GOLGA2,GP1BA,GPRC5A,GPRC5B,GPS1,GREM1,GRHL2,GRM4,GRM5,GSK3A,GSKIP,GSTP1,GTF2H1,H2AFY,HACD3,HEXIM1,HEXIM2,HGF,HGS,HHEX,HMBOX1,HMGB1,HMGCR,HMGN1,HNRNPA2B1,HNRNPD,HNRNPU,HRAS,HSP90AB1,HSPA2,HSPA5,HSPB1,HSPH1,HTR2A,HTR2B,IBTK,IFNG,IGF1,IGF1R,IGF2,IKBKG,IL12B,IL18,IL1B,IL23A,IL23R,IL6,INAVA,INCA1,INPP5K,INS,IQGAP1,IQGAP3,IRAK1,IRAK3,IRGM,IRS1,IRS2,ITGA1,JAK2,JTB,KARS,KAT2B,KITLG,KLF4,KRAS,LAMTOR2,LAMTOR3,LAT,LATS1,LATS2,LAX1,LCP2,LDB2,LEP,LIMK1,LMO4,LPAR1,LPAR3,LRP5,LRP6,LRP8,LRRC15,LRRC19,LRRC3,LRRC3C,LRRC4,LRRC4C,LRRC66,LRRK2,LRRTM1,LRRTM3,LRRTM4,LRTM1,LRTM2,LYN,MAD2L1,MAD2L2,MADD,MAGEC2,MALT1,MAP2K2,MAP2K3,MAP2K4,MAP2K6,MAP2K7,MAP3K1,MAP3K10,MAP3K11,MAP3K12,MAP3K13,MAP3K14,MAP3K15,MAP3K19,MAP3K2,MAP3K21,MAP3K3,MAP3K4,MAP3K5,MAP3K6,MAP3K7,MAP3K7CL,MAP3K8,MAP3K9,MAP4K1,MAP4K3,MAP4K4,MAPK1,MAPK10,MAPK11,MAPK14,MAPK15,MAPK3,MAPK8IP1,MAPK8IP3,MAPKAP1,MAPKAPK2,MAPKAPK3,MAPKAPK5,MAPRE3,MAPT,MARK2,MAS1,MASTL,MBIP,MCPH1,MEN1,MIF,MINK1,MLLT1,MLST8,MMD,MMD2,MOS,MRE11,MRNIP,MST1,MST1R,MSTN,MTCP1,MTOR,MUC20,MUL1,MVP,MYC,MYOCD,NAB2,NAF1,NBN,NCF1,NCK1,NCK2,NCKAP1L,NEK1,NEK10,NEK4,NEK7,NEURL1,NF1,NF2,NGF,NIPSNAP2,NKX3-1,NLRC5,NOD1,NOX4,NPFFR2,NPM1,NPRL2,NRBF2,NRG1,NRG3,NRK,NTF3,NTRK1,NTRK3,NUP62,NVL,P2RX7,PABPN1,PAK1,PAK2,PAK3,PAK4,PAK5,PARK7,PARM1,PARN,PARP16,PARP4,PDCD10,PDE5A,PDE6H,PDGFA,PDGFB,PDGFC,PDGFD,PDGFRB,PDPK1,PEA15,PFKFB1,PFKFB2,PHPT1,PIF1,PIFO,PIH1D1,PIK3CA,PIK3CG,PIK3IP1,PIK3R1,PIK3R2,PIK3R3,PIK3R5,PIK3R6,PIN1,PINK1,PINX1,PKD1,PKD2,PKIA,PKIB,PKIG,PKMYT1,PKN1,PLA2G1B,PLCE1,PLCG1,PLK1,PNKP,PODN,PODNL1,POT1,PPARG,PPEF2,PPM1E,PPM1F,PPP1R1A,PPP1R1C,PPP1R3F,PPP2R3C,PPP2R5A,PRDX3,PREX1,PRKAA1,PRKACA,PRKACG,PRKAG2,PRKAR1A,PRKAR1B,PRKAR2B,PRKCD,PRKCQ,PRKCZ,PRKD1,PRKN,PRKRIP1,PRLR,PROK1,PROK2,PROX1,PRR5,PSEN1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTEN,PTK2,PTK2B,PTPN1,PTPN11,PTPN22,PTPRJ,PYCARD,PYDC1,RAB1A,RAC2,RAD50,RAF1,RALB,RANBP2,RAP1A,RAP2B,RAP2C,RAPGEF1,RAPGEF2,RASGRP1,RASSF2,RB1,RBL1,RELN,RFC2,RFC3,RFC4,RGCC,RGN,RGS14,RGS2,RGS3,RGS4,RICTOR,RIPK1,RIPK2,RIPK3,ROBO1,ROR2,RPL11,RPL23,RPL5,RPS27A,RPS3,RPS7,RPTOR,RTN4R,RTN4RL2,RUBCN,S100A12,SAA1,SASH1,SBK2,SDC4,SERINC1,SERINC2,SERINC5,SERPINB3,SESN2,SFN,SFRP1,SFRP2,SH3BP5,SHB,SHC1,SHC2,SIRT1,SLC11A1,SLC27A1,SLC9A3R1,SMAD7,SMCR8,SMG6,SMG8,SMPD1,SMYD3,SNCA,SNX6,SNX9,SOCS1,SOCS2,SOCS3,SOCS4,SOCS5,SOCS6,SOCS7,SOD1,SORL1,SPAG9,SPDYA,SPDYE16,SPDYE4,SPDYE5,SPDYE6,SPRED1,SPRED2,SPRY1,SPRY2,SPTSSB,SRC,SRCIN1,STAP1,STK24,STK26,STK38,STK4,STRADA,STRADB,STUB1,SYK,TAB1,TAB2,TAB3,TAOK1,TAOK2,TARBP2,TCL1A,TCL1B,TCP1,TDGF1,TEK,TELO2,TENM1,TERF1,TESC,TGFB1,TGFB2,TGFBR1,TGFBR2,THBS1,THY1,TIAM1,TIGAR,TIRAP,TLR3,TLR4,TLR6,TLR9,TMEM189-UBE2V1,TNF,TNFAIP3,TNFAIP8L3,TNFRSF10A,TNFRSF10B,TNFRSF11A,TNFSF11,TNFSF15,TNIK,TNKS,TOM1L1,TOPORS,TP53,TP73,TPD52L1,TPX2,TRAF2,TRAF4,TRAF6,TRAF7,TRIB1,TRIB2,TRIB3,TRPT1,TSC2,TSG101,TTN,TXN,UBASH3B,UBC,UBE2C,UBE2D1,UBE2E1,UBE2I,UBE2L3,UBE2N,UBE2S,UCHL1,UCN,UNC119,UVRAG,UVSSA,VAC14,VANGL2,VAPB,VAV2,VAV3,VEGFA,VLDLR,VPS25,WARS,WDR81,WDR91,WEE2,WNK1,WNT11,WNT3A,WNT5A,WNT7B,WRAP53,WWTR1,XRCC5,XRCC6,YWHAG,ZFP36,ZFP91,ZFYVE28,ZNF16,ZNF622,ZNF675,ZYG11A,ZYG11B	TetrapodAncestor	300
GO.Biological.Process	GO:0060548	negative.regulation.of.cell.death	1	1e-300	1e-300	1e-300	1.231513e+0	AAMDC,AARS,AATF,ABCB4,ABL1,ACAA2,ACKR3,ADA,ADAM8,ADAMTS20,ADAR,ADCYAP1,ADCYAP1R1,ADNP,ADNP2,ADORA1,ADORA2A,AGAP2,AGO4,AGR2,AGR3,AHI1,AIF1,AIPL1,AKR1B1,AKT2,ALB,ALKBH1,AMBRA1,AMIGO2,ANGPT1,ANGPT4,ANGPTL4,ANXA1,ANXA4,ANXA5,APBB2,API5,APIP,APOE,APOH,AQP1,AR,ARAF,ARF4,ARG2,ARHGDIA,ARHGEF2,ARL6IP1,ARNT2,ARRB1,ARRB2,ASCL1,ASIC2,ASNS,ATAD3A,ATF4,ATF5,ATG5,ATOH1,ATP13A2,AURKA,AURKB,AVP,AXL,BABAM2,BAD,BAG1,BAG4,BAG6,BARD1,BARHL1,BAX,BCL10,BCL11B,BCL2,BCL2A1,BCL2L1,BCL2L10,BCL2L12,BCL2L2,BCL2L2-PABPN1,BCL3,BCL6,BDKRB2,BDNF,BECN1,BFAR,BID,BIRC2,BIRC3,BIRC5,BIRC6,BMP4,BMP5,BMP7,BNIP1,BNIP3,BNIP3L,BRAF,BRCA1,BTBD10,BTC,BTG2,C8orf4,CACYBP,CAMK1D,CARD14,CARD16,CASP2,CASP3,CASP8,CAST,CAT,CAV1,CBL,CBX4,CCAR2,CCL19,CCL2,CCL21,CCL5,CCND2,CCR7,CD27,CD34,CD38,CD44,CD59,CD74,CDC73,CDK1,CDK5,CDKN1A,CDKN1B,CDKN2D,CEBPB,CFDP1,CFL1,CFLAR,CHD8,CHGA,CHL1,CHMP2A,CHMP4A,CHMP4B,CHST11,CIAPIN1,CIB1,CIDEA,CITED1,CITED2,CLCF1,CLN3,CLU,CNTF,CNTFR,COL2A1,CORO1A,CPEB4,CREB1,CREB3,CREB3L1,CRYAA,CRYAB,CSF1R,CSF3,CSNK2A1,CTGF,CTH,CTNNA1,CTNNB1,CTSH,CTTN,CX3CL1,CX3CR1,CYR61,DAB2,DAD1,DAPK1,DCPS,DDB1,DDIAS,DDRGK1,DDX3X,DFFA,DHCR24,DHRS2,DKK1,DLL1,DNAJA1,DNAJA3,DNAJB6,DOCK8,DPEP1,DRAXIN,DSTYK,DUS2,DUSP1,DYNLT1,DYRK3,EDN1,EDNRB,EEF2K,EFNA1,EGFR,EGR3,EIF2AK2,ELL3,EN1,EPCAM,EPO,ERBB4,ERC1,ERCC5,EYA1,EYA2,EYA3,EYA4,F2R,FABP1,FADD,FAIM2,FAM129B,FAS,FASLG,FBXO7,FCER1G,FCMR,FFAR4,FGF10,FGF2,FGF20,FGF21,FGF4,FGFR2,FGG,FHL2,FIGNL1,FLNA,FLT3LG,FLT4,FMN2,FOXC1,FOXC2,FOXE3,FOXO1,FXN,FZD1,FZD3,FZD9,GABRA5,GABRB2,GABRB3,GAS6,GATA3,GATA6,GBA,GCLM,GDF5,GDNF,GFRAL,GHSR,GLI2,GLI3,GLO1,GNRH1,GOLPH3,GPAM,GPNMB,GPR37,GPR37L1,GREM1,GRIK2,GRIN1,GRINA,GRK5,GSTP1,HAND2,HAX1,HCK,HCLS1,HDAC1,HDAC2,HDAC3,HERPUD1,HEY2,HGF,HIF1A,HIGD1A,HIGD2A,HIP1R,HIPK2,HMGA2,HMGB2,HMGCR,HMGN5,HMOX1,HNF1B,HNRNPK,HPN,HRAS,HSF1,HSH2D,HSP90AB1,HSP90B1,HSPA5,HSPA9,HSPB1,HSPB6,HSPH1,HTR2B,HTRA2,HTT,HYOU1,HYPK,ID1,IDO1,IER3,IFI6,IFIT3,IGBP1,IGF1,IGF1R,IHH,IKBKB,IKBKG,IL10,IL13,IL19,IL1A,IL1B,IL2,IL2RB,IL31RA,IL4,IL6,IL6ST,IL7,ING2,INS,INSL6,IRAK1,IRF7,IRS2,ISL1,ITCH,ITGA5,ITGAV,ITGB1,ITPKB,ITSN1,IVNS1ABP,JAK2,JAK3,JUN,KANK2,KDM1A,KDM2B,KIFAP3,KITLG,KLF4,KLHL20,KRAS,KRIT1,LACRT,LAMP3,LEF1,LEP,LGALS3,LGMN,LHX4,LIG4,LIMS2,LMNA,LRP1,LRP6,LRPAP1,LRRK2,LTK,MAD2L1,MAEA,MAEL,MAG,MALT1,MAP2K4,MAP3K12,MAP4K4,MAPK8,MAPK8IP1,MDK,MDM2,MDM4,MECOM,MECP2,MEF2C,MEIS3,MERTK,MET,MICAL1,MIEN1,MIF,MMP9,MNT,MPO,MPV17L,MRE11,MSH2,MSX1,MSX2,MTDH,MTOR,MUC1,MYC,MYDGF,MYO18A,MYOCD,NAA15,NAA16,NAA35,NAA38,NAIP,NANOS3,NAT8,NCK1,NCKAP1L,NCOA7,NDNF,NDUFS3,NEFL,NES,NEUROD1,NFKB1,NGF,NGFR,NKX2-5,NKX2-6,NKX3-2,NLE1,NLRC4,NME2,NME5,NOC2L,NOG,NOL3,NOS3,NOTCH1,NOTCH2,NOV,NPAS2,NPC1,NPM1,NPY5R,NQO1,NR1H4,NR4A2,NR4A3,NRP1,NTF3,NTF4,NTRK1,NTRK2,NTRK3,NTSR1,NUAK2,NUGGC,NUP62,OGG1,OPA1,OSR1,OXR1,PACRG,PAFAH2,PAK2,PAK5,PALB2,PARK7,PARP16,PAX2,PAX4,PAX7,PAX8,PCGF2,PCID2,PDCD1,PDCD10,PDE12,PDE3A,PDE8A,PDGFRB,PDPK1,PDPN,PEA15,PELI3,PF4,PGAP2,PHIP,PIAS1,PIDD1,PIH1D1,PIK3CA,PIK3CG,PIK3R1,PIM1,PIM2,PIM3,PIN1,PINK1,PIP,PKHD1,PLAC8,PLCG2,PLK1,PLK2,PLK3,PM20D1,POR,POU3F3,POU3F4,POU4F1,PPARA,PPARD,PPARGC1A,PPIF,PPP5C,PPT1,PRAMEF1,PRAMEF12,PRAMEF14,PRAMEF19,PRAMEF20,PRDX2,PRDX3,PRDX5,PRELID1,PRKAA1,PRKAA2,PRKCA,PRKCD,PRKCG,PRKCH,PRKCI,PRKCQ,PRKCZ,PRKD1,PRKDC,PRKN,PRLR,PROC,PROK2,PROKR1,PROP1,PSAP,PSEN1,PSEN2,PSMC1,PSMC5,PSMD10,PSME3,PTEN,PTGFR,PTH,PTK2,PTK2B,PTPN1,PTTG1IP,PYCR1,RAD18,RAF1,RAG1,RAMP2,RARA,RARB,RARG,RASA1,RB1CC1,RBCK1,REL,RELA,RETREG1,RFFL,RGL2,RGN,RHBDD1,RIPK1,RIPK2,RNF144B,RNF34,RPS27A,RPS6,RPS6KA1,RPS6KA3,RRM2B,RRN3,RXFP2,SCG2,SCRT2,SCX,SEMA4D,SEMA5A,SERPINB13,SERPINB2,SERPINB9,SETX,SFN,SFRP1,SFRP2,SH3RF1,SHC1,SIAH2,SIRT1,SIRT4,SIRT5,SLC25A27,SLC25A5,SLC30A10,SLC35F6,SLC39A10,SLC40A1,SLC46A2,SLC9A1,SMAD4,SMO,SNAI1,SNAI2,SNCA,SNCB,SOCS2,SOCS3,SOD1,SOD2,SON,SORL1,SOX10,SOX11,SOX4,SOX8,SOX9,SPHK1,SPHK2,SPRY2,SQSTM1,SRC,SRSF6,STAMBP,STAR,STIL,STRADB,STXBP1,SYCP2,SYCP2L,SYNGAP1,SYVN1,TAF9,TAF9B,TAX1BP1,TBX1,TBX3,TCL1A,TDGF1,TEAD2,TEK,TERT,TEX11,TFAP2A,TFAP2B,TFAP2D,TGFBR1,THBS1,THOC6,TIGAR,TIMP1,TLDC1,TLE1,TM7SF3,TMBIM1,TMBIM4,TMBIM6,TMEM109,TMEM14A,TMEM161A,TMIGD1,TNF,TNFAIP3,TNFAIP8,TNFRSF10A,TNFRSF10B,TNFRSF10C,TNFRSF10D,TNFRSF18,TNFRSF1B,TNFSF10,TNFSF14,TNFSF18,TNIP2,TOPORS,TP53,TP63,TP73,TPT1,TRADD,TRAF2,TRAF6,TRAP1,TRIAP1,TRIM32,TSC22D4,TTPA,TWIST1,TWIST2,TXN,TXNDC5,TYRO3,UBC,UBE2V2,UCN,UCP2,UFL1,UNC5B,UNG,USP47,VEGFA,VHLL,VIL1,VNN1,VPS35,VPS4B,VSTM2L,VTCN1,WFS1,WISP1,WISP2,WNK3,WNT1,WNT11,WNT16,WNT3A,WNT4,WNT5A,WNT7A,WNT9A,XBP1,XIAP,XRCC2,YBX3,YME1L1,YWHAE,YWHAZ,ZC3H12A,ZC3HC1,ZFAND6,ZFPM2,ZNF16,ZNF385A,ZNF830,ZPR1	TetrapodAncestor	300
GO.Biological.Process	GO:0072358	cardiovascular.system.development	1	1e-300	1e-300	1e-300	1.270821e+0	AAMP,ABL1,ACKR3,ACTA2,ACVR2B,ACVRL1,ADAM15,ADAM8,ADAMTS9,ADGRA2,ADGRG1,ADIPOR2,ADM2,AGGF1,AHR,AMOT,ANGPT1,ANGPT2,ANGPT4,ANGPTL4,ANKRD17,ANPEP,ANTXR1,AP2B1,APOB,APOD,APOE,APOLD1,AQP1,ARHGAP22,ARHGAP24,ARID1A,ARID2,ATPIF1,B4GALT1,B9D1,BAK1,BAX,BCAS3,BMP4,BMPER,BMPR1A,BMPR2,C1GALT1,C5orf42,CALCRL,CAV1,CCBE1,CCL2,CCM2,CD34,CDC42,CDH13,CDH2,CDH5,CHD7,CIB1,CITED1,COL15A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL8A1,COL8A2,CRB2,CRKL,CSPG4,CTGF,CTNNB1,CUL7,CX3CL1,CXCL8,CXCR3,CYP1B1,CYR61,DAB2IP,DCTN5,DHCR7,DLL1,DLL4,DLX3,DNM2,DYNC2H1,E2F7,E2F8,ECSCR,EDN1,EFNA1,EFNB2,EGF,EGFL7,EGR1,EGR3,EIF2AK3,ELK3,ENG,ENPEP,ENSG00000259753,EPAS1,EPC1,EPGN,EPHA1,EPHA2,EPHB1,EPHB2,EPHB3,EPHB4,ERAP1,EREG,ERRFI1,ESM1,ETS1,EYA1,FBXW7,FBXW8,FGF1,FGF10,FGF18,FGF2,FGF6,FGF9,FGFR1,FGFR2,FLT1,FLT4,FLVCR1,FMNL3,FN1,FOSL1,FOXC1,FOXC2,FOXF1,FOXH1,FOXN1,FOXO1,FOXS1,FZD4,FZD5,FZD8,GAB1,GATA6,GBX2,GDF2,GGNBP2,GJA4,GJC1,GLI3,GNA13,GPC3,GPLD1,GPR4,GREM1,HAND1,HAND2,HAS2,HDAC7,HEG1,HES1,HEY1,HEY2,HHEX,HIF1A,HIF3A,HMOX1,HOXA1,HPGD,HPSE,HRG,HS6ST1,HSPG2,ID1,IHH,IL18,IMMP2L,ITGA5,ITGAV,ITGB1,ITGB8,JAG1,JAM3,JMJD6,JUN,JUNB,KCNQ1,KDM6A,KLF5,KRIT1,LAMA5,LEF1,LEMD3,LEP,LEPR,LGALS8,LIF,LOX,LOXL1,LOXL2,LRP1,LRP5,LUZP1,LYL1,MAP3K3,MAPK1,MAPK14,MCAM,MDM2,MEF2C,MEGF8,MEIS1,MEOX2,MESP1,MFGE8,MIB1,MMP14,MMP19,MMRN2,MYDGF,MYH9,MYLK,MYO1E,MYOCD,NAA15,NCL,NDNF,NDP,NDST1,NF1,NFATC4,NKX2-5,NKX3-1,NOG,NOS3,NOTCH1,NOTCH3,NOTCH4,NOV,NOX5,NPRL3,NR4A1,NRP1,NRP2,NSDHL,NTRK2,NUS1,NXN,OSR1,OTULIN,OVOL2,PAXIP1,PCSK5,PDCD10,PDCD6,PDCL3,PDGFA,PDGFB,PDGFRB,PDPN,PECAM1,PIK3CA,PIK3CG,PIK3R6,PITX2,PKD1,PKD2,PKNOX1,PLCD3,PLG,PLXDC1,PLXND1,POGLUT1,PPP3CB,PRCP,PRDM1,PRICKLE1,PRKCA,PRKD1,PRKD2,PRKX,PROK1,PROK2,PROP1,PROX1,PRRX1,PSEN1,PTEN,PTK2,PTK2B,PTK7,PTPN14,PTPRB,QKI,RAMP1,RAMP2,RAPGEF1,RAPGEF2,RAPGEF3,RASA1,RASIP1,RBPJ,RECK,RHOJ,RIC8A,RNF213,ROBO1,ROBO4,ROM1,RSPO3,S100A7,S1PR1,SAT1,SCG2,SEC24B,SEMA3C,SEMA3E,SEMA4A,SEMA5A,SETD2,SFRP2,SGCB,SGPL1,SH2D2A,SHB,SHC1,SIRT1,SLC12A6,SLIT2,SLITRK5,SMAD7,SMO,SNX17,SOCS3,SOS1,SOX17,SOX18,SOX4,SPHK1,SPHK2,SPI1,SPINT1,SPRED1,SRF,SRPK2,SRPX2,STAB2,STK4,STRA6,SUFU,SYK,T,TAB1,TAL1,TBX1,TBX2,TBX20,TBX3,TBX5,TCF21,TDGF1,TEAD2,TEK,TFAP2B,TGFB1,TGFB2,TGFBI,TGFBR1,TGFBR2,THBS1,THSD7A,THY1,TIE1,TIPARP,TMED2,TMEM100,TMEM2,TMEM204,TMEM231,TMPRSS6,TNFRSF12A,TNFSF12,TNNI3,TSPAN12,TYMP,UBP1,UNC5B,VASH1,VASH2,VAV2,VAV3,VEGFA,VEGFB,VEGFC,VEGFD,VEZF1,VHLL,WARS,WARS2,WASF2,WNT11,WNT7A,WNT7B,XBP1,ZBTB14,ZC3H12A,ZFAND5,ZFP36L1,ZFPM2,ZMIZ1	TetrapodAncestor	300
GO.Biological.Process	GO:1901701	cellular.response.to.oxygen-containing.compound	1	1e-300	1e-300	1e-300	1.263169e+0	AACS,AANAT,ABCA1,ABCB4,ABCC2,ABL1,ABL2,ACACA,ACTR2,ADAM9,ADAMTS13,ADCY2,ADCY3,ADCY4,ADCY5,ADCY8,ADIPOQ,ADNP2,ADPRHL2,ADRB2,AGER,AGRN,AGT,AGTR1,AGTR2,AGTRAP,AHCYL1,AICDA,AIF1,AIFM1,AKAP6,AKAP8,AKR1B1,AKT2,ANKRD1,ANKZF1,ANXA1,AOC1,AP3S1,APC,APEX1,APLP1,APOA4,APOB,APOBEC1,APP,APPL1,AQP1,AQP2,AQP8,AR,ARG1,ARHGEF2,ARID1B,ATF4,ATP2B1,ATP2B4,ATP6AP1,ATP6V0A4,ATP6V0B,ATP6V0C,ATP6V0D1,ATP6V0D2,ATP6V0E1,ATP6V0E2,ATP6V1B1,ATP6V1B2,ATP6V1C1,ATP6V1C2,ATP6V1D,ATP6V1E1,ATP6V1E2,ATP6V1G1,ATP6V1G3,ATP6V1H,AVPR1A,AXL,BAD,BAIAP2L2,BCAR1,BCL11A,BCL2L1,BCR,BECN1,BGLAP,BNIP3,BRCA1,BRINP1,BRINP2,BRINP3,BRIP1,BTK,C2CD5,CA2,CACNA1A,CACNA2D1,CACNB1,CACTIN,CALCRL,CAMK2A,CAMKK2,CAPN10,CAPN2,CARD16,CARD17,CASP1,CASP4,CASP9,CASR,CASTOR1,CAV1,CAV2,CBX8,CCL2,CCL3,CCL5,CCL7,CCNA2,CCNB1,CCR5,CD14,CD180,CD36,CD40,CD6,CD80,CD86,CDC5L,CDC6,CDC73,CDH1,CDK1,CDK19,CDK2,CDK4,CDK5,CDK5R1,CDK6,CEBPB,CEBPE,CERS1,CFLAR,CFTR,CHEK2,CHRM1,CHRM2,CHRM3,CHRM4,CHRM5,CHRNA3,CHRNB2,CHUK,CIB2,CLDN1,CLEC7A,CMPK2,COL16A1,COL1A1,COL1A2,COL3A1,COL5A2,COL6A1,COLEC12,CPB2,CPEB1,CPEB2,CPEB4,CPS1,CPT1A,CREB1,CRHBP,CRHR1,CRHR2,CRK,CRYGD,CSF3,CSH1,CSK,CTNNA1,CTNNB1,CX3CR1,CXCL10,CXCL16,CXCL6,CXCL8,CYBA,CYBB,CYFIP1,CYP1B1,CYP24A1,CYP26B1,CYP7A1,DAB2IP,DAPK1,DCPS,DDIT4,DDX11,DDX18,DENND4C,DGAT2,DMTN,DNM1L,DNM2,DNMT3A,DNMT3B,DPEP1,DRD1,DRD5,DYNAP,E2F1,ECT2,EDN1,EDNRB,EEF2K,EFNA5,EGFR,EGR1,EIF4E,EIF4EBP1,ELK1,ENDOG,ENPP1,ENSG00000256632,ENSG00000278139,EPHA3,EPHA4,ERCC6L2,ERN1,ERRFI1,ESR1,ETS1,EZH2,EZR,FABP1,FAM210B,FANCC,FBXO32,FDX1,FER,FFAR2,FFAR3,FGF21,FGF23,FGFR2,FIS1,FOS,FOXC2,FOXO1,FOXO4,FXN,FZD10,FZD4,FZD7,GAB1,GABPA,GAS6,GATA4,GCGR,GCK,GCLM,GDAP1,GH1,GH2,GHR,GHRHR,GHSR,GJB3,GLP1R,GLP2R,GLRA1,GLRA2,GLRX2,GNA11,GNA15,GNAI1,GNAQ,GNB2,GNG10,GNG11,GNG12,GNG13,GNG2,GNG3,GNG7,GNG8,GNRHR,GOT1,GPD1,GPER1,GPLD1,GRB2,GRIK5,GRK2,GRM5,GSK3A,GSTP1,GUCY1B3,H2AFZ,HAMP,HAVCR2,HCK,HCN1,HCN2,HCN3,HCN4,HDAC2,HDAC5,HDAC8,HDAC9,HMGB2,HMGCS1,HNRNPD,HNRNPU,HSF1,HSP90B1,HSPA5,HTRA2,ID1,ID3,IDE,IFNB1,IFNG,IGF1,IGF1R,IGF2,IGFBP5,IL10,IL12A,IL12B,IL15,IL18,IL18BP,IL18RAP,IL1B,IL24,IL6,INHBA,INHBB,INPP5K,INS,IPO5,IRAK1,IRF3,IRF8,IRGM,IRS1,IRS2,IRS4,ITGA2,ITPR2,JAK2,JAK3,JUN,JUP,KAT2B,KAT5,KCNB1,KCNC2,KCNE1,KCNJ11,KCNK4,KCNMB1,KCNQ1,KDM1A,KDM6B,KIF18A,KL,KLF1,KLF10,KLF11,KLF15,KLF2,KLF3,KLF4,KLF5,KLF9,KLRK1,KRT13,LAMTOR2,LAMTOR3,LAMTOR4,LARP1,LARS,LBP,LCN2,LDLR,LEP,LGALS1,LILRB2,LIN28A,LITAF,LPAR1,LPIN1,LRP1,LRP6,LRP8,LRRK2,LTK,LY96,LYN,LYPD1,MAP1LC3A,MAP2K4,MAP2K6,MAP3K5,MAPK1,MAPK14,MAPK3,MAPK8,MAPK9,MAS1,MAX,MDM2,MEF2C,MEN1,METTL21C,MGARP,MGST1,MLC1,MLXIPL,MMP3,MMP9,MPO,MPV17,MRC1,MSN,MSTN,MSX2,MTDH,MTOR,MYB,MYOD1,MYOG,NCF1,NCOA3,NDEL1,NDOR1,NET1,NEURL1,NEUROD1,NFATC4,NFKB1,NFKBIB,NGFR,NKX6-1,NLRP7,NME1,NME2,NME8,NOD1,NOS2,NOS3,NOX4,NPAS4,NQO1,NR1D1,NR1H3,NR1H4,NR3C1,NR4A1,NR4A2,NR4A3,NRIP1,NTRK2,NTRK3,NUGGC,OPA1,OPRK1,OR51E2,OSR1,OXR1,P2RX4,P2RY4,P2RY6,PABPN1,PAF1,PAK1,PARK7,PARP1,PAX2,PCGF2,PCK1,PCK2,PCNA,PDCD10,PDE2A,PDE3A,PDE4B,PDE4D,PDGFB,PDGFC,PDGFD,PDK2,PDK3,PDPK1,PDXP,PENK,PHEX,PHIP,PID1,PIK3C2A,PIK3CA,PIK3CG,PIK3R1,PIK3R2,PIK3R3,PIM1,PKD2,PKLR,PKM,PLA2G1B,PLAA,PLCB1,PLEKHA1,PLSCR4,POR,POU4F1,PPARD,PPARG,PPARGC1A,PPARGC1B,PPIF,PPP3CA,PPP5C,PRDX1,PRDX2,PRDX3,PRDX5,PRKAA1,PRKAA2,PRKACA,PRKACG,PRKAR1A,PRKAR1B,PRKAR2B,PRKCB,PRKCD,PRKCE,PRKCI,PRKCZ,PRKD1,PRKDC,PRKN,PRL,PRLR,PRPF8,PSEN1,PTAFR,PTCH1,PTEN,PTGDR,PTGER2,PTGER4,PTGFR,PTK2,PTK2B,PTK7,PTN,PTPN1,PTPN22,PTPRA,PTPRK,PTPRN2,PXN,PYCARD,RAB11B,RAB11FIP2,RAB11FIP5,RAB13,RAB31,RAB8A,RAD51,RAF1,RAP1A,RAP1B,RAPGEF1,RAPGEF2,RAPGEF3,RARA,RARG,RASGRP4,RECQL5,RELA,RET,RGS10,RGS8,RHOQ,RIPK2,ROCK2,ROMO1,RORB,RORC,RPE65,RPL23,RPS3,RPTOR,RRAGA,RRAGD,RUVBL2,RWDD1,RYR2,RYR3,SCARB1,SELENOT,SESN2,SESN3,SETX,SFRP1,SH2B2,SH3BP4,SHC1,SHMT1,SHPK,SIPA1,SIRT1,SIRT2,SLC25A33,SLC26A3,SLC29A1,SLC2A8,SLC30A10,SLC38A9,SLC5A5,SLC6A4,SLC8A1,SLC8A3,SLC9A1,SLIT2,SLURP2,SMARCC1,SMARCD1,SMO,SMYD3,SNCA,SNRNP70,SNW1,SOCS1,SOCS2,SOCS7,SOD1,SOD2,SOD3,SOGA1,SORBS1,SOS1,SOX10,SOX4,SOX9,SP1,SPAAR,SPI1,SPIDR,SPON2,SPP1,SRC,SRD5A1,SREBF1,SRF,SRSF5,SSTR1,SSTR2,SSTR3,STAP1,STAR,STAT6,STC1,STRA8,STXBP4,T,TAF1,TBC1D4,TBX1,TBXA2R,TCIRG1,TEAD2,TESC,TFPI,TGFB1,TH,TICAM1,TICAM2,TIMELESS,TIRAP,TLR2,TLR4,TLR5,TLR6,TNC,TNF,TNFAIP3,TNFRSF1B,TNIP1,TNIP2,TNIP3,TP53,TP53INP1,TRA2B,TRAF2,TRAF6,TREM2,TRIB3,TRPC6,TRPM2,TRPV1,TSHR,TSPO,TUSC5,TWF2,UBR1,UBR2,UCP1,UCP2,UGT1A1,UGT3A2,UMODL1,UNC13B,UPF1,USF1,USP8,VAMP2,VDR,WDR35,WDTC1,WNT1,WNT10B,WNT11,WNT3,WNT3A,WNT5A,WNT6,WNT7B,WNT8B,WNT9A,WNT9B,XBP1,XRCC5,XRN1,YES1,YWHAG,ZC3H12A,ZEB1,ZFP36,ZFP36L1,ZFP36L2,ZNF106,ZNF16,ZNF277,ZNF580,ZNF703	TetrapodAncestor	300
GO.Biological.Process	GO:1902533	positive.regulation.of.intracellular.signal.transduction	1	1e-300	1e-300	1e-300	1.261002e+0	ABL1,ABRA,ACKR3,ACTN4,ADA,ADAM8,ADAM9,ADCYAP1,ADCYAP1R1,ADGRG1,ADIPOQ,ADIPOR1,ADORA1,ADORA2B,ADRA1A,ADRA1B,ADRA2A,ADRA2B,ADRA2C,ADRB2,ADRB3,AGER,AGO1,AGO3,AGT,AJUBA,AKAP12,AKAP13,AKAP5,AKAP6,AKR1B1,ALK,ALKAL1,ALOX15,ALS2,ANGPT1,ANKRD1,ANKRD17,ANKRD6,APOA1,APOL3,APP,AR,ARAF,ARHGAP8,ARL2BP,ARL6IP5,ARRB1,ARRB2,ATM,ATP6AP1,ATR,AUTS2,AVPI1,AXL,BAD,BAG4,BANK1,BAX,BCAP31,BCL10,BCL2,BCL2L1,BCL2L11,BCLAF1,BECN1,BID,BIRC2,BIRC3,BMP2,BMP4,BMPER,BRAF,BRD4,BST2,BTC,C18orf32,C1QBP,C1QTNF1,C1QTNF12,C1QTNF2,C5,C8orf4,CALCR,CALM1,CALM2,CALM3,CALR,CANT1,CARD10,CARD11,CARD14,CARD16,CARTPT,CASP1,CASP10,CASP8,CAT,CAV1,CAV2,CAVIN3,CBL,CC2D1A,CCDC22,CCL1,CCL11,CCL13,CCL14,CCL15,CCL15-CCL14,CCL16,CCL17,CCL18,CCL19,CCL2,CCL21,CCL22,CCL23,CCL3,CCL3L3,CCL4,CCL4L2,CCL5,CCL7,CCL8,CCR1,CCR7,CD14,CD19,CD24,CD27,CD28,CD36,CD3E,CD40,CD44,CD74,CD80,CD81,CD86,CD8A,CDC42,CDH13,CDH2,CDK1,CDK10,CDON,CFLAR,CHD5,CHI3L1,CHUK,CIB1,CLCF1,CLEC16A,CLEC6A,CNTF,COL3A1,COPS8,CRK,CRKL,CRLF3,CSF1,CSF1R,CSF3,CSK,CSPG4,CTF1,CTGF,CTH,CTNNB1,CX3CL1,CXCL10,CXCL11,CXCL9,CXCR4,CXXC5,CYP1B1,CYSLTR2,DAB2IP,DAXX,DBNL,DCN,DDRGK1,DDT,DDX5,DDX60,DFNA5,DGKI,DKK1,DLG5,DNAJC27,DNM1L,DRD2,DRD4,DSTYK,DUSP15,DUSP19,DUSP22,DUSP6,DUSP7,DUSP9,DVL3,DYNLT1,ECT2,EDA,EDA2R,EDAR,EDN1,EDN3,EEF1D,EFNA1,EGF,EGFR,EIF2AK2,EPGN,EPHA4,EPHA8,EPO,ERBB2,ERBB4,ERCC6,EREG,ERN1,ERN2,ERP29,EZH2,F10,F2,F2R,F2RL1,F2RL3,F3,F7,FADD,FAM58A,FASLG,FBXO18,FBXW7,FFAR4,FGD2,FGF1,FGF10,FGF16,FGF17,FGF18,FGF19,FGF2,FGF20,FGF21,FGF22,FGF23,FGF3,FGF4,FGF6,FGF7,FGF9,FGFR1,FGFR2,FGFR3,FGFR4,FGG,FGR,FIS1,FKBP1A,FLCN,FLNA,FLT1,FLT4,FRMD7,FRS2,FSHR,FZD10,FZD4,FZD5,FZD7,FZD8,GAB1,GADD45A,GADD45B,GADD45G,GAREM1,GAS6,GATA3,GCNT2,GDF6,GH1,GHR,GIP,GJA1,GLIPR2,GNG3,GOLPH3,GOLT1B,GPER1,GPNMB,GPR17,GPR18,GPR183,GPR20,GPR35,GPR37,GPR37L1,GPR4,GPR55,GPR65,GPRC5B,GRB2,GREM1,GRM4,GSTM2,HACD3,HAND2,HAP1,HAVCR2,HAX1,HBEGF,HCLS1,HCRTR1,HDAC2,HDAC3,HES1,HES5,HEXIM1,HGF,HIC1,HINT1,HIP1,HIPK2,HMGB1,HMGCR,HMOX1,HPSE,HRAS,HSF1,HTR2A,HTR2B,HTR2C,HTR6,HTT,IAPP,ICOS,IFIT5,IFNA2,IFNG,IFNL1,IGF1,IGF2,IGFBP4,IGFBP5,IKBKB,IKBKE,IKBKG,IL12A,IL12B,IL13,IL15,IL18,IL18R1,IL19,IL1B,IL2,IL20,IL20RA,IL21,IL23A,IL23R,IL24,IL26,IL31RA,IL4,IL5,IL6,IL6R,IL6ST,INAVA,INS,IQGAP1,IQGAP3,IRAK1,IRAK4,IRF3,IRS1,IRS2,ISL1,ITGA1,ITGAV,ITPKB,ITSN1,JAK2,JCAD,JPH2,JUN,KARS,KIAA1161,KISS1,KITLG,KL,KRAS,KSR1,LACRT,LAMTOR2,LAMTOR3,LAMTOR4,LARS,LCK,LEP,LGALS1,LGALS9,LHCGR,LIF,LIN28A,LITAF,LMCD1,LPAR1,LPAR3,LPAR4,LPAR6,LRRK2,LTBR,LURAP1,LYN,MADD,MALT1,MAP2K2,MAP2K3,MAP2K4,MAP2K6,MAP2K7,MAP3K1,MAP3K10,MAP3K11,MAP3K12,MAP3K13,MAP3K14,MAP3K15,MAP3K2,MAP3K21,MAP3K3,MAP3K4,MAP3K5,MAP3K6,MAP3K7,MAP3K7CL,MAP3K8,MAP3K9,MAP4K1,MAP4K3,MAP4K4,MAPK1,MAPK10,MAPK11,MAPK14,MAPK3,MAPK8IP1,MAPK8IP3,MAPKAPK2,MAPKAPK3,MAPKAPK5,MARCO,MAS1,MC1R,MEIS3,MET,MIB2,MID1,MID2,MIER1,MIF,MINK1,MIOS,MLST8,MMD2,MOS,MST1R,MSX1,MTDH,MTOR,MUC20,MUL1,MYDGF,NCF1,NCK1,NCK2,NDFIP1,NDFIP2,NDRG4,NDST1,NECAB2,NEK10,NEK6,NENF,NGF,NKX3-1,NLGN1,NOD1,NOS1AP,NOTCH1,NOTCH2,NOX4,NPTN,NPY5R,NQO2,NRG1,NRG2,NRG4,NRK,NRP1,NTF3,NTRK1,NTRK2,NTRK3,NUP62,OPRK1,OPRM1,OSM,P2RX2,P2RX3,P2RX4,P2RX5,P2RX7,P2RY1,P2RY10,P2RY8,PAK1,PAK3,PARK7,PARP14,PARP9,PDCD10,PDE5A,PDE6H,PDE8A,PDGFA,PDGFB,PDGFC,PDGFD,PDGFRB,PEA15,PELI1,PELI2,PF4,PHB,PIAS4,PIH1D1,PIK3AP1,PIK3CA,PIK3CD,PIK3CG,PIK3R1,PIK3R2,PIK3R5,PIK3R6,PIM2,PINK1,PKD2,PKN1,PLA2G1B,PLA2G2A,PLA2G5,PLA2G6,PLCB1,PLCE1,PLCG1,PLEKHF1,PLEKHG5,PLK2,PLXNB1,PMAIP1,PPARD,PPP5C,PRKAA1,PRKCA,PRKCB,PRKCE,PRKCZ,PRKD1,PRKD2,PRKN,PRKRA,PRL,PRLR,PRMT1,PROK1,PROK2,PRR5,PRR5L,PSAP,PSEN1,PTEN,PTGIR,PTK2,PTK2B,PTP4A3,PTPN1,PTPN11,PTPN22,PTPRJ,PYCARD,RAC1,RAD9A,RAF1,RAP1A,RAP1B,RAPGEF1,RAPGEF2,RASD2,RASGEF1A,RASGRF1,RASGRP1,RASGRP4,RASSF2,RB1CC1,RBCK1,RC3H1,RC3H2,REL,RELA,RELN,RGL2,RHEB,RHOC,RICTOR,RIPK1,RIPK2,RIPK3,RIT2,RNF31,ROBO1,ROR2,RPL11,RPL23,RPS27A,RPS3,RPS7,RPTOR,RRAGA,RRAGD,RTN4,RTN4R,RYK,S100A12,S100A13,S100A4,S100A7,S100A8,S100A9,S100B,SAA1,SASH1,SDCBP,SEC13,SECTM1,SELP,SEMA4C,SEMA4D,SEMA5A,SEMA7A,SEPT4,SERINC3,SERPINA12,SFPQ,SHARPIN,SHC1,SHC2,SIAH1,SIRT1,SKIL,SLC30A10,SLC38A9,SLC44A2,SLC9A1,SLC9A3R1,SMCR8,SOCS3,SOD1,SORBS3,SOS1,SOX11,SOX2,SOX9,SPAG9,SPHK1,SPOP,SPPL3,SPRED1,SPRED2,SPRY2,SRC,SSTR4,STAP2,STK24,STK26,SYK,TAB1,TAB2,TAB3,TAOK1,TAOK2,TBK1,TBX1,TDGF1,TEK,TELO2,TENM1,TERF2IP,TFG,TGFB1,TGFB2,TGFBR1,TGM2,THBS1,THPO,TIAM1,TICAM1,TICAM2,TIMP2,TIRAP,TLR2,TLR3,TLR4,TLR6,TLR9,TMED4,TMEM101,TMEM189-UBE2V1,TNF,TNFAIP8L3,TNFRSF10A,TNFRSF10B,TNFRSF11A,TNFRSF18,TNFRSF19,TNFRSF1A,TNFSF10,TNFSF11,TNFSF14,TNFSF15,TNFSF18,TNIK,TNIP2,TP53,TP73,TPD52L1,TRADD,TRAF2,TRAF4,TRAF5,TRAF6,TRAF7,TRAT1,TRDN,TREM2,TRIM13,TRIM22,TRIM25,TRIM32,TRIM38,TRIM44,TRIM5,TRIM62,TRIM8,TRIP6,TSPAN6,TSPYL5,TXN,UBC,UBE2I,UBE2N,UBE3A,UNC5B,UNC5CL,VANGL2,VAPA,VAV1,VEGFA,WDR24,WDR59,WLS,WNT11,WNT16,WNT5A,WNT7A,WNT7B,WWC1,XCL1,XCL2,XDH,ZAP70,ZC3H12A,ZDHHC13,ZDHHC17,ZFP91,ZNF385A,ZNF622	TetrapodAncestor	300
GO.Biological.Process	GO:1903037	regulation.of.leukocyte.cell-cell.adhesion	1	1e-300	1e-300	1e-300	1.410149e+0	ABL1,ADA,ADAM8,ADORA2A,AGER,AIF1,ANXA1,AP3D1,ARG1,ARG2,ASS1,BAD,BCL10,BCL6,BMP4,BRAF,BTLA,CAMK4,CARD11,CASP3,CAV1,CBFB,CCDC88B,CCL19,CCL2,CCL21,CCL28,CCL5,CCR2,CCR7,CD1D,CD2,CD209,CD24,CD247,CD27,CD274,CD276,CD28,CD300A,CD3D,CD3E,CD3G,CD44,CD46,CD47,CD5,CD55,CD59,CD6,CD74,CD80,CD83,CD86,CDC42,CEBPB,CLC,CLEC4G,CLECL1,CORO1A,CR1,CSK,CTLA4,CTNNB1,CYP26B1,DHPS,DLG1,DLG5,DNAJA3,DOCK8,DROSHA,DTX1,DUSP10,DUSP22,DUSP3,EBI3,EFNB1,EFNB2,EFNB3,EPO,ERBB2,ETS1,FADD,FAM49B,FANCA,FLOT2,FOXJ1,FOXN1,FOXP3,GATA3,GLI2,GLI3,GNRH1,GPAM,GPNMB,GRAP2,GRB2,GSN,HAS2,HAVCR2,HES1,HHLA2,HLX,HMGB1,HSPH1,ICOS,IDO1,IFNA2,IFNB1,IFNG,IFNL1,IFNL2,IFNL3,IGF1,IGF2,IGFBP2,IHH,IL10,IL12A,IL12B,IL12RB1,IL15,IL18,IL1B,IL1RL2,IL2,IL20RB,IL21,IL23A,IL23R,IL27,IL36B,IL4,IL6,IL6ST,IL7,IL7R,IRF1,IRF4,ITCH,ITGA4,ITPKB,JAK3,KIRREL1,KLF4,KLRK1,LAT,LAX1,LCK,LEP,LGALS1,LGALS3,LGALS9,LILRB2,LILRB4,LOXL3,LRRC32,LYN,MAD1L1,MALT1,MAP3K14,MAP3K7,MAP3K8,METTL3,MYB,NCK1,NCK2,NCKAP1L,NDFIP1,NFATC2,NFKBID,NPHS1,NR4A3,PAG1,PAK1,PAK2,PAK3,PAWR,PDCD1,PDCD1LG2,PDE5A,PDPK1,PELI1,PIK3CA,PIK3R1,PIK3R6,PLA2G2D,PLA2G2F,PNP,PPARA,PRDM1,PRELID1,PRKAR1A,PRKCQ,PRKCZ,PTAFR,PTPN11,PTPN22,PYCARD,RAC1,RAC2,RAG1,RARA,RASAL3,RASGRP1,RC3H1,RIPK2,RIPK3,RIPOR2,RPS3,RUNX1,SART1,SASH3,SCGB1A1,SDC4,SELENOK,SHB,SIRPG,SIT1,SLC46A2,SMAD7,SOCS1,SOCS5,SOCS6,SOD1,SOS1,SOX13,SPINK5,SPN,SRC,SYK,TARM1,TESPA1,TFRC,TGFB1,TGFBR2,THY1,TIGIT,TMEM131L,TMIGD2,TNF,TNFAIP8L2,TNFRSF13C,TNFRSF14,TNFRSF18,TNFRSF21,TNFSF11,TNFSF13B,TNFSF14,TNFSF18,TNFSF9,TRAF2,TRAF6,VAV1,VCAM1,VNN1,VSIG4,VTCN1,XBP1,XCL1,YES1,ZAP70,ZBTB1,ZBTB16,ZBTB7B,ZC3H8,ZEB1,ZMIZ1,ZNF683,ZP3,ZP4	TetrapodAncestor	300
GO.Biological.Process	GO:2000145	regulation.of.cell.motility	1	1e-300	1e-300	1e-300	1.223888e+0	AAMP,ABHD2,ABHD6,ABI3,ABL1,ABL2,ABR,ACE,ACKR3,ACTN4,ACVR1B,ACVRL1,ADA,ADAM15,ADAM8,ADAM9,ADAMTS9,ADARB1,ADGRA2,ADGRB1,ADGRG1,ADGRG3,ADIPOQ,ADIPOR1,ADORA1,ADORA3,ADRA2A,AGT,AGTR2,AIF1,AJUBA,AKT2,ALOX15B,AMOT,AMOTL1,ANGPT1,ANGPT2,ANGPT4,ANO6,ANXA1,ANXA3,AP1AR,APC,APEX1,APOD,APOE,APOH,APP,AQP1,ARAP3,ARHGAP18,ARHGAP4,ARHGDIB,ARHGEF2,ARHGEF39,ARHGEF7,ARID2,ARPIN,ATOH8,ATP5A1,ATP8A1,BAG4,BBS4,BCAR1,BCAS3,BCL2,BCR,BDKRB1,BMP10,BMP2,BMP4,BMP5,BMP7,BMPER,BMPR1A,BMPR2,BRAF,BST1,BST2,BTC,C16orf45,C1QBP,C3AR1,C5,C5orf30,CALR,CAMK1D,CAMSAP3,CAPN7,CARMIL1,CARMIL2,CATSPER1,CBLL1,CCBE1,CCDC125,CCL1,CCL11,CCL19,CCL2,CCL21,CCL28,CCL3,CCL4,CCL5,CCL7,CCL8,CCR1,CCR2,CCR6,CCR7,CD274,CD300A,CD40,CD74,CD81,CDH13,CDK5,CDK6,CEMIP,CERS2,CFAP20,CGA,CHRD,CIB1,CITED2,CLASP1,CLASP2,CMKLR1,COL18A1,COL1A1,COL3A1,CORO1A,CORO1B,CPEB1,CPNE3,CREB3,CRK,CSF1,CSF1R,CSNK2B,CTNNA1,CTSH,CX3CL1,CX3CR1,CXCL1,CXCL10,CXCL11,CXCL13,CXCL14,CXCL16,CXCL2,CXCL3,CXCL5,CXCL6,CXCL8,CXCL9,CXCR3,CYGB,CYP19A1,CYP1B1,CYR61,DAB2,DAB2IP,DACH1,DAPK2,DAPK3,DCN,DDR2,DDRGK1,DDT,DDX58,DIAPH1,DLC1,DLG5,DLL4,DMTN,DOCK10,DOCK4,DOCK5,DOCK8,DPEP1,DPYSL3,DRD1,DRD2,DUSP10,EDN1,EDN2,EDN3,EFNA1,EGF,EGFR,ELP3,EMP2,ENG,ENPP2,ENSG00000259753,ENSG00000260272,EPB41L4B,EPB41L5,EPCAM,EPHA1,EPHA2,EPPIN,EPPIN-WFDC6,ERBB2,ERBB4,EREG,ETS1,EVL,F10,F2R,F2RL1,F3,F7,FADD,FAM60A,FAM83H,FAM89B,FBLN1,FBXO31,FER,FERMT3,FES,FGF1,FGF10,FGF16,FGF18,FGF2,FGF4,FGF7,FGFR1,FGFR1OP,FGR,FLCN,FLNA,FLRT2,FLT1,FLT4,FN1,FOXC2,FOXF1,FOXO4,FRMD5,FSHB,FUZ,GAB1,GAS6,GATA3,GCNT2,GDF2,GLIPR2,GNA12,GNA13,GNRH1,GPER1,GPLD1,GPNMB,GPR18,GPR183,GPSM3,GRB7,GREM1,GSTP1,GTSE1,HACE1,HAS2,HBEGF,HDAC4,HDAC5,HDAC7,HDAC9,HGF,HIF1A,HMCN2,HMGB1,HMOX1,HRAS,HRG,HSPA5,HSPB1,IDH2,IFITM1,IFNG,IGF1,IGF1R,IGFBP5,IGSF10,IL12A,IL1A,IL1B,IL1R1,IL23A,IL24,IL33,IL4,IL6,IL6R,INS,INSL3,INSM1,IQCF1,IQGAP1,IRS2,ITGA2,ITGA2B,ITGA3,ITGA4,ITGA5,ITGAV,JAG1,JAG2,JAK2,JAM3,JCAD,JUN,KANK1,KARS,KIF20B,KITLG,KLF4,KLRK1,KRIT1,KRT16,LAMA1,LAMA2,LAMA3,LAMA4,LAMA5,LAMB1,LBP,LDB2,LDLRAD4,LEF1,LGALS3,LGALS9,LGR6,LMNA,LMO4,LPAR1,LRCH1,LRIG2,LRP1,LRRC15,LYN,MACF1,MADCAM1,MAGI2,MAPK1,MAPK14,MAPK3,MAPRE1,MARVELD3,MCAM,MCC,MCTP1,MDM2,MEMO1,MEOX2,MET,MIA3,MIEN1,MIF,MIIP,MINK1,MKKS,MMP10,MMP14,MMP28,MMP9,MMRN2,MOSPD2,MPP1,MSN,MTA2,MTOR,MYADM,MYLK,MYO1C,MYOCD,MYPN,MYSM1,NAV3,NBL1,NCK1,NCKAP1L,NDRG4,NF1,NF2,NIPBL,NISCH,NKX6-1,NOG,NOTCH1,NOV,NOX4,NRG1,NRG2,NRG3,NRG4,NRP1,NRP2,NTF3,NTRK3,NUMB,ONECUT1,P2RX4,P2RY6,PADI2,PAK1,PAK3,PARD6B,PBLD,PDCD10,PDCD6,PDGFA,PDGFB,PDGFC,PDGFD,PDGFRB,PDPK1,PDPN,PF4,PF4V1,PFN1,PFN2,PGAM4,PHLDA2,PHLDB2,PHPT1,PIK3CD,PIK3R1,PIN1,PITX2,PKN1,PKP2,PLA2G7,PLAA,PLAU,PLCB1,PLCG1,PLET1,PLPP3,PLVAP,PLXNA1,PLXNA2,PLXNB2,PLXND1,PODN,PODXL,PPARD,PPARG,PPARGC1A,PPBP,PPM1F,PRCP,PREX1,PRKCA,PRKCE,PRKD1,PRKD2,PRKX,PROX1,PRR5L,PTAFR,PTEN,PTGER4,PTK2,PTK2B,PTN,PTP4A1,PTPN23,PTPRG,PTPRJ,PTPRK,PTPRM,PTPRR,PTPRU,PYCARD,RAB25,RAC1,RAC2,RAF1,RAP2A,RAP2B,RAP2C,RAPGEF2,RARRES2,RCC2,RDX,RECK,RELN,RET,RETN,RFFL,RGCC,RGN,RHOD,RIPK3,RIPOR1,RIPOR2,RNASE10,RNF20,RNF41,ROBO1,ROBO4,ROCK2,ROR2,RRAS,RRAS2,RREB1,RTN4,RUFY3,S100A14,S100A7,S1PR1,SASH1,SCAI,SCARB1,SCRT1,SCRT2,SDC4,SDCBP,SELENOK,SELP,SEMA3A,SEMA3C,SEMA4A,SEMA4D,SEMA5A,SEMA6A,SEMA6D,SEMG1,SEMG2,SERPINB3,SERPINE2,SFRP1,SFRP2,SGK1,SH3BP1,SLC26A5,SLC8A1,SLC8B1,SLC9A3R1,SLIT2,SLURP1,SMAD7,SMURF2,SNAI1,SNAI2,SOD2,SORL1,SOX14,SOX9,SP100,SPAG9,SPATA13,SPHK1,SPOCK2,SPOCK3,SPRED1,SPRY2,SRC,SRCIN1,SRF,SRGAP1,SRGAP2,SRGAP2B,SRGAP2C,SRGAP3,SRPX2,SST,STAP1,STARD13,STC1,STK24,STK26,STRAP,STX4,SUN2,SYDE1,SYNE2,SYNJ2BP,TAC1,TAC4,TACR3,TACSTD2,TBCCD1,TBX5,TDGF1,TEK,TERT,TGFB1,TGFB2,TGFBR1,TGFBR2,THBS1,THBS4,THY1,TIAM1,TIE1,TIMP1,TIRAP,TMEFF2,TMIGD1,TMIGD3,TMSB4Y,TNF,TNFAIP6,TNFRSF14,TNFRSF18,TNFSF14,TNFSF18,TP53INP1,TRIB1,TRIM32,TRIP6,TWIST1,ULK4,UNC5C,UNC5D,UTS2,VASH1,VCL,VEGFA,VEGFB,VEGFC,VEGFD,VIL1,VTN,WNT11,WNT4,WNT5A,WNT7A,XBP1,XCL1,ZC3H12A,ZMYND8,ZNF580,ZNF609,ZNF703,ZP3	TetrapodAncestor	300
GO.Biological.Process	GO:0002237	response.to.molecule.of.bacterial.origin	39	9.683193e-320	1.250778e-315	3.207123e-317	1.422168e+0	ABCA1,ABCC2,ABCC8,ABL1,ABR,ACP5,ADAM9,ADAMTS13,ADH5,AICDA,AKAP8,AKIRIN2,ALAD,ALPL,ANKRD1,APOB,ARG1,AXL,BCL10,BCR,BDKRB1,C4B,CACTIN,CARD16,CARD17,CASP1,CASP3,CASP8,CASP9,CCL2,CCL3,CCL5,CCR5,CCR7,CD14,CD180,CD24,CD27,CD36,CD40,CD6,CD80,CD86,CD96,CDC73,CDK19,CDK4,CEBPB,CEBPE,CHUK,CITED1,CLDN1,CMPK2,CNR1,CNR2,CPEB1,CPS1,CSF2RB,CSF3,CX3CR1,CXCL1,CXCL10,CXCL11,CXCL13,CXCL16,CXCL2,CXCL3,CXCL5,CXCL6,CXCL8,CXCL9,CYP1A1,CYP1A2,CYP27B1,DAB2IP,DCN,DUSP10,EDN1,EDNRB,ENSG00000173366,EPO,F2R,FAS,FASLG,FER,FGF10,FGFR2,FOS,FZD5,GCH1,GHSR,GJA1,GNG12,GNRH1,GSTP1,HAMP,HAVCR2,HCK,HDAC2,HDAC5,HMGB2,HNRNPA0,HPGD,HSF1,IDO1,IFNAR1,IFNG,IL10,IL10RA,IL12A,IL12B,IL12RB2,IL13,IL18,IL18BP,IL1B,IL23R,IL24,IL6,INAVA,IRAK1,IRAK3,IRF3,IRF8,IRGM,JAK2,JUN,JUNB,KCNJ8,KLRK1,LBP,LCN2,LGALS9,LILRB2,LITAF,LOXL1,LRRC70,LTBR,LY96,LYN,MALT1,MAOB,MAPK1,MAPK14,MAPK3,MAPK8,MAPKAPK2,MAPKAPK3,MEF2C,MGST1,MGST2,MPO,MRC1,MTDH,NFKB1,NFKB2,NFKBIB,NGFR,NLRP7,NOCT,NOS2,NOS3,NOTCH1,NR1D1,NR1H3,NR1H4,NUGGC,OPRK1,OPRM1,OTUD5,P2RX7,PABPN1,PAF1,PALM3,PCK1,PCK2,PDE4B,PDE4D,PELI1,PENK,PF4,PF4V1,PLAA,PLCG2,PLSCR4,PPARD,PPARGC1A,PPBP,PRDX3,PRKCE,PRPF8,PTAFR,PTGER1,PTGER2,PTGER4,PTGES,PTGFR,PTGIR,PTPN22,PYCARD,RARA,RELA,RELT,REN,RIPK2,RPS6KA3,S100A14,S100A7,S100A8,SCARB1,SCGB1A1,SELE,SELP,SHPK,SIRT2,SLC11A1,SLPI,SNCA,SPON2,SRC,SRR,SSC5D,STAP1,STAR,TAC1,TBXA2R,TFPI,TGFB1,TH,THBD,TICAM1,TICAM2,TIMP4,TIRAP,TLR1,TLR2,TLR4,TLR5,TLR6,TLR9,TNF,TNFAIP3,TNFRSF10A,TNFRSF10B,TNFRSF10C,TNFRSF10D,TNFRSF11A,TNFRSF11B,TNFRSF14,TNFRSF18,TNFRSF1A,TNFRSF1B,TNFRSF21,TNFRSF25,TNFRSF4,TNFRSF8,TNFRSF9,TNIP1,TNIP2,TNIP3,TRAF6,TREM2,TRIB1,TRIM6,TSPO,UGT1A1,UPF1,VCAM1,WDR35,WNT5A,XBP1,ZC3H12A,ZFP36	TetrapodAncestor	300
GO.Biological.Process	GO:0032496	response.to.lipopolysaccharide	40	1.639785e-317	2.118110e-313	5.295276e-315	1.428891e+0	ABCA1,ABCC2,ABCC8,ABL1,ABR,ACP5,ADAM9,ADAMTS13,ADH5,AICDA,AKAP8,AKIRIN2,ALAD,ALPL,ANKRD1,APOB,ARG1,AXL,BCR,BDKRB1,CACTIN,CARD16,CARD17,CASP1,CASP3,CASP8,CASP9,CCL2,CCL3,CCL5,CCR5,CCR7,CD14,CD180,CD27,CD36,CD40,CD6,CD80,CD86,CD96,CDC73,CDK19,CDK4,CEBPB,CEBPE,CHUK,CITED1,CLDN1,CMPK2,CNR1,CNR2,CPEB1,CPS1,CSF2RB,CSF3,CX3CR1,CXCL1,CXCL10,CXCL11,CXCL13,CXCL16,CXCL2,CXCL3,CXCL5,CXCL6,CXCL8,CXCL9,CYP1A1,CYP1A2,CYP27B1,DAB2IP,DCN,DUSP10,EDN1,EDNRB,EPO,F2R,FAS,FASLG,FER,FGF10,FGFR2,FOS,GCH1,GHSR,GJA1,GNG12,GNRH1,GSTP1,HAMP,HAVCR2,HCK,HDAC2,HDAC5,HMGB2,HNRNPA0,HPGD,HSF1,IDO1,IFNAR1,IFNG,IL10,IL10RA,IL12A,IL12B,IL12RB2,IL13,IL18,IL18BP,IL1B,IL23R,IL24,IL6,IRAK1,IRAK3,IRF3,IRF8,IRGM,JAK2,JUN,JUNB,KCNJ8,KLRK1,LBP,LCN2,LGALS9,LILRB2,LITAF,LOXL1,LTBR,LY96,LYN,MAOB,MAPK1,MAPK14,MAPK3,MAPK8,MAPKAPK2,MAPKAPK3,MEF2C,MGST1,MGST2,MPO,MRC1,MTDH,NFKB1,NFKB2,NFKBIB,NGFR,NLRP7,NOCT,NOS2,NOS3,NOTCH1,NR1D1,NR1H3,NR1H4,NUGGC,OPRK1,OPRM1,OTUD5,P2RX7,PABPN1,PAF1,PALM3,PCK1,PCK2,PDE4B,PDE4D,PELI1,PENK,PF4,PF4V1,PLAA,PLCG2,PLSCR4,PPARD,PPARGC1A,PPBP,PRDX3,PRKCE,PRPF8,PTAFR,PTGER1,PTGER2,PTGER4,PTGES,PTGFR,PTGIR,PTPN22,PYCARD,RARA,RELA,RELT,REN,RIPK2,RPS6KA3,S100A14,S100A7,S100A8,SCARB1,SCGB1A1,SELE,SELP,SHPK,SLC11A1,SLPI,SNCA,SPON2,SRC,SRR,STAP1,STAR,TAC1,TBXA2R,TFPI,TGFB1,TH,THBD,TICAM1,TICAM2,TIMP4,TIRAP,TLR2,TLR4,TLR5,TNF,TNFAIP3,TNFRSF10A,TNFRSF10B,TNFRSF10C,TNFRSF10D,TNFRSF11A,TNFRSF11B,TNFRSF14,TNFRSF18,TNFRSF1A,TNFRSF1B,TNFRSF21,TNFRSF25,TNFRSF4,TNFRSF8,TNFRSF9,TNIP1,TNIP2,TNIP3,TRAF6,TREM2,TRIB1,TRIM6,TSPO,UGT1A1,UPF1,VCAM1,WDR35,WNT5A,XBP1,ZC3H12A,ZFP36	TetrapodAncestor	300
GO.Biological.Process	GO:0022409	positive.regulation.of.cell-cell.adhesion	41	4.428656e-317	5.720495e-313	1.395243e-314	1.432851e+0	ADA,ADAM8,AGER,AIF1,ALOX15,ANK3,ANXA1,AP3D1,BAD,BCL10,BCL6,BMP7,BTLA,CARD11,CAV1,CCDC88B,CCL19,CCL2,CCL21,CCL5,CCR2,CD1D,CD209,CD24,CD247,CD27,CD274,CD276,CD28,CD3D,CD3E,CD3G,CD44,CD46,CD47,CD5,CD55,CD59,CD6,CD74,CD80,CD83,CD86,CDC42,CITED2,CLECL1,CORO1A,CSK,CTLA4,CXCL13,DHPS,DMTN,DNAJA3,DOCK8,DUSP10,EBI3,EFNB1,EFNB2,EFNB3,EPO,ETS1,FADD,FAM49B,FGG,FLOT1,FLOT2,FOXA1,FOXA2,FOXP3,FSTL3,GATA3,GCNT2,GLI2,GLI3,GPAM,GRAP2,GRB2,HAS2,HAVCR2,HES1,HHLA2,HLX,HMGB1,HSPH1,ICOS,IFNG,IGF1,IGF2,IGFBP2,IHH,IL10,IL12A,IL12B,IL12RB1,IL15,IL18,IL1B,IL1RL2,IL2,IL21,IL23A,IL23R,IL36B,IL4,IL6,IL6ST,IL7,IL7R,ITGA4,ITPKB,JAK3,KIF26B,KIRREL1,KLRK1,LCK,LEP,LGALS1,LGALS9,LILRB2,LILRB4,LYN,MALT1,MAP3K14,MAP3K7,MAP3K8,MYB,MYO10,NCK1,NCK2,NCKAP1L,NPHS1,NR4A3,PAK1,PAK2,PAK3,PDCD1,PDCD1LG2,PDPK1,PDPN,PIEZO1,PIK3CA,PIK3R1,PIK3R6,PLPP3,PNP,PODXL,PRKCQ,PRKCZ,PTAFR,PTPN11,PYCARD,RAC1,RAG1,RARA,RASAL3,RASGRP1,RIPK2,RNASE10,RPS3,SART1,SASH3,SELENOK,SHB,SIRPG,SMAD7,SOCS1,SOCS5,SOX2,SPN,SRC,SYK,TESPA1,TFRC,TGFB1,TGFBR2,THY1,TMIGD2,TNF,TNFRSF13C,TNFRSF14,TNFSF11,TNFSF13B,TNFSF14,TNFSF9,TRAF2,TRAF6,VAV1,VCAM1,VNN1,VTCN1,WNT3A,WNT5A,XBP1,XCL1,YES1,ZAP70,ZBTB1,ZBTB16,ZMIZ1,ZP3,ZP4	TetrapodAncestor	300
GO.Biological.Process	GO:0001568	blood.vessel.development	42	1.505616e-314	1.944804e-310	4.630486e-312	1.271756e+0	AAMP,ACKR3,ACTA2,ACVR2B,ACVRL1,ADAM15,ADAM8,ADAMTS9,ADGRA2,ADGRG1,ADIPOR2,ADM2,AGGF1,AHR,AMOT,ANGPT1,ANGPT2,ANGPT4,ANGPTL4,ANKRD17,ANPEP,ANTXR1,AP2B1,APOB,APOD,APOE,APOLD1,AQP1,ARHGAP22,ARHGAP24,ARID1A,ARID2,ATPIF1,B4GALT1,BAK1,BAX,BCAS3,BMP4,BMPER,BMPR1A,BMPR2,C1GALT1,C5orf42,CALCRL,CAV1,CCBE1,CCL2,CCM2,CD34,CDC42,CDH13,CDH2,CDH5,CHD7,CIB1,CITED1,COL15A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A1,COL8A1,COL8A2,CRKL,CSPG4,CTGF,CTNNB1,CUL7,CX3CL1,CXCL8,CXCR3,CYP1B1,CYR61,DAB2IP,DCTN5,DHCR7,DLL1,DLL4,DLX3,DNM2,DYNC2H1,E2F7,E2F8,ECSCR,EDN1,EFNA1,EFNB2,EGF,EGFL7,EGR1,EGR3,EIF2AK3,ELK3,ENG,ENPEP,ENSG00000259753,EPAS1,EPGN,EPHA1,EPHA2,EPHB1,EPHB2,EPHB3,EPHB4,ERAP1,EREG,ESM1,ETS1,EYA1,FBXW8,FGF1,FGF10,FGF18,FGF2,FGF6,FGF9,FGFR1,FGFR2,FLT1,FLT4,FLVCR1,FMNL3,FN1,FOSL1,FOXC1,FOXC2,FOXF1,FOXH1,FOXN1,FOXO1,FOXS1,FZD4,FZD5,FZD8,GAB1,GATA6,GBX2,GDF2,GGNBP2,GJA4,GJC1,GLI3,GNA13,GPC3,GPLD1,GPR4,GREM1,HAND1,HAND2,HAS2,HDAC7,HEG1,HES1,HEY1,HEY2,HHEX,HIF1A,HIF3A,HMOX1,HOXA1,HPGD,HPSE,HRG,HS6ST1,HSPG2,ID1,IHH,IL18,ITGA5,ITGAV,ITGB1,ITGB8,JAG1,JAM3,JMJD6,JUN,JUNB,KLF5,KRIT1,LAMA5,LEF1,LEMD3,LEP,LEPR,LOX,LOXL1,LOXL2,LRP1,LRP5,LUZP1,LYL1,MAP3K3,MAPK1,MAPK14,MCAM,MDM2,MEF2C,MEGF8,MEIS1,MEOX2,MESP1,MFGE8,MIB1,MMP14,MMP19,MMRN2,MYDGF,MYH9,MYLK,MYO1E,MYOCD,NAA15,NCL,NDNF,NDST1,NF1,NFATC4,NKX2-5,NKX3-1,NOG,NOS3,NOTCH1,NOTCH3,NOTCH4,NOV,NOX5,NPRL3,NR4A1,NRP1,NRP2,NSDHL,NTRK2,NUS1,OSR1,OTULIN,OVOL2,PAXIP1,PCSK5,PDCD10,PDCD6,PDCL3,PDGFA,PDGFB,PDGFRB,PECAM1,PIK3CA,PIK3CG,PIK3R6,PITX2,PKD1,PKD2,PKNOX1,PLCD3,PLG,PLXDC1,PLXND1,PRCP,PRDM1,PRICKLE1,PRKCA,PRKD1,PRKD2,PRKX,PROK1,PROK2,PROP1,PROX1,PRRX1,PSEN1,PTEN,PTK2,PTK2B,PTK7,PTPRB,QKI,RAMP1,RAMP2,RAPGEF1,RAPGEF2,RAPGEF3,RASA1,RASIP1,RBPJ,RECK,RNF213,ROBO1,ROBO4,RSPO3,S100A7,S1PR1,SAT1,SCG2,SEC24B,SEMA3C,SEMA3E,SEMA4A,SEMA5A,SETD2,SFRP2,SGPL1,SH2D2A,SHB,SHC1,SIRT1,SLC12A6,SLIT2,SMAD7,SMO,SNX17,SOCS3,SOS1,SOX17,SOX18,SOX4,SPHK1,SPHK2,SPI1,SPINT1,SPRED1,SRF,SRPK2,SRPX2,STAB2,STK4,STRA6,SUFU,SYK,T,TAB1,TAL1,TBX1,TBX2,TBX20,TBX3,TBX5,TCF21,TDGF1,TEAD2,TEK,TFAP2B,TGFB1,TGFB2,TGFBI,TGFBR1,TGFBR2,THBS1,THSD7A,THY1,TIE1,TIPARP,TMED2,TMEM100,TMEM2,TMPRSS6,TNFRSF12A,TNFSF12,TNNI3,TSPAN12,TYMP,UBP1,UNC5B,VASH1,VASH2,VAV2,VAV3,VEGFA,VEGFB,VEGFC,VEGFD,VEZF1,VHLL,WARS,WARS2,WASF2,WNT11,WNT7A,WNT7B,XBP1,ZBTB14,ZC3H12A,ZFP36L1,ZFPM2,ZMIZ1	TetrapodAncestor	300
GO.Biological.Process	GO:0040017	positive.regulation.of.locomotion	43	7.414555e-312	9.577381e-308	2.227298e-309	1.289389e+0	AAMP,ABL1,ACKR3,ACTN4,ACVR1B,ADAM8,ADAM9,ADGRA2,ADRA2A,AGER,AGT,AIF1,AKT2,AMOTL1,ANGPT1,ANGPT4,ANO6,ANXA3,APC,APP,AQP1,ARHGEF2,ARHGEF39,ARHGEF7,ARTN,ATOH8,ATP5A1,ATP8A1,BAG4,BCAR1,BCAS3,BCL2,BDKRB1,BMP2,BMP4,BMP7,BMPR2,BVES,C1QBP,C3AR1,CALR,CAMK1D,CAPN7,CARMIL1,CARMIL2,CASR,CAV2,CBLL1,CCBE1,CCL1,CCL11,CCL19,CCL2,CCL21,CCL3,CCL4,CCL5,CCL7,CCL8,CCR1,CCR2,CCR4,CCR6,CCR7,CD274,CD40,CD74,CDH13,CEMIP,CFAP20,CGA,CHMP2A,CHMP2B,CHMP3,CHMP4B,CHMP4C,CIB1,CLASP1,CLASP2,CMKLR1,COL18A1,COL1A1,CORO1A,CPEB1,CPNE3,CREB3,CRK,CSF1,CSF1R,CTSH,CXCL1,CXCL10,CXCL11,CXCL13,CXCL14,CXCL16,CXCL2,CXCL3,CXCL5,CXCL6,CXCL8,CXCL9,CYR61,DAB2,DAB2IP,DAPK2,DAPK3,DDB1,DDR2,DDRGK1,DIAPH1,DMTN,DOCK4,DOCK5,DOCK8,DRD1,DSCAM,EDN1,EDN2,EDN3,EGF,EGFR,ELP3,ENPP2,ENSG00000260272,EPB41L4B,EPB41L5,EPCAM,EPHA1,ETS1,F10,F2R,F2RL1,F3,F7,FADD,FAM83H,FAM89B,FBXO31,FER,FERMT3,FGF1,FGF10,FGF16,FGF18,FGF2,FGF7,FGFR1,FGFR1OP,FGR,FLNA,FLT1,FLT4,FN1,FOXC2,FOXF1,FOXO4,FSHB,GAB1,GAS6,GATA3,GCNT2,GLIPR2,GPER1,GPLD1,GPNMB,GPSM3,GRB7,GTSE1,HAS2,HBEGF,HDAC4,HDAC7,HDAC9,HGF,HIF1A,HMCN2,HMGB1,HRAS,HSPA5,HSPB1,IFNG,IGF1,IGF1R,IL12A,IL16,IL1A,IL1B,IL1R1,IL23A,IL4,IL6,IL6R,INS,INSL3,INSM1,IQCF1,IQGAP1,IRS2,ITGA2,ITGA2B,ITGA3,ITGA4,ITGA5,ITGAV,JAK2,JCAD,JUN,KARS,KIF20B,KITLG,LAMB1,LBP,LEF1,LGALS3,LGALS9,LGR6,LPAR1,LRRC15,LYN,MADCAM1,MAPK1,MAPK14,MAPK3,MAPRE1,MCAM,MDM2,MEGF8,MET,MIA3,MIEN1,MMP14,MMP9,MOSPD2,MTOR,MYADM,MYLK,MYO1C,NCKAP1L,NIPBL,NOTCH1,NOX4,NRP1,NRP2,NTF3,NTRK3,NUMB,ONECUT1,OPRK1,P2RX4,P2RY6,PAK1,PAK3,PC,PDCD10,PDCD6,PDGFA,PDGFB,PDGFC,PDGFD,PDGFRB,PDPN,PF4,PF4V1,PFN1,PGAM4,PHPT1,PIK3CD,PIK3R1,PLA2G7,PLAA,PLAU,PLCG1,PLET1,PLPP3,PLVAP,PODXL,PPBP,PPM1F,PREX1,PRKCA,PRKCE,PRKD1,PRKD2,PROX1,PTAFR,PTK2,PTK2B,PTP4A1,PYCARD,RAB25,RAC1,RAC2,RAPGEF2,RARRES2,RDX,RELN,RET,RETN,RHOD,RIPOR1,RIPOR2,RNASE10,ROCK2,ROR2,RRAS2,RREB1,RTN4,RUFY3,S100A14,S100A7,S1PR1,SASH1,SCARB1,SCG2,SDCBP,SELENOK,SELP,SEMA3A,SEMA3C,SEMA4D,SEMA5A,SEMA6A,SEMA6D,SERPINB3,SLC26A5,SLC8A1,SLIT2,SMURF2,SNAI1,SNAI2,SOD2,SOX9,SPAG9,SPHK1,SPOCK2,SPRY2,SRC,SRGAP2C,SRPX2,STX3,STX4,SUN2,SYDE1,SYNE2,TAC1,TAC4,TACR3,TDGF1,TEK,TERT,TGFB1,TGFB2,TGFBR1,TGFBR2,THBS1,THBS4,THY1,TIAM1,TIRAP,TNF,TNFAIP6,TNFRSF14,TNFRSF18,TNFSF14,TNFSF18,TRIM32,TRIP6,TSG101,TUBB2B,TWIST1,UTS2,VAPA,VEGFA,VEGFB,VEGFC,VEGFD,VIL1,VPS35,VPS37B,VPS4A,VPS4B,VTN,WNT11,WNT5A,WNT7A,XBP1,XCL1,ZC3H12A,ZNF580,ZNF609,ZNF703,ZP3	TetrapodAncestor	307.019
GO.Biological.Process	GO:0030335	positive.regulation.of.cell.migration	44	2.329238e-307	3.008677e-303	6.837902e-305	1.300122e+0	AAMP,ABL1,ACKR3,ACTN4,ACVR1B,ADAM8,ADAM9,ADGRA2,ADRA2A,AGT,AIF1,AKT2,AMOTL1,ANGPT1,ANGPT4,ANO6,ANXA3,APC,APP,AQP1,ARHGEF2,ARHGEF39,ARHGEF7,ATOH8,ATP5A1,ATP8A1,BAG4,BCAR1,BCAS3,BCL2,BDKRB1,BMP2,BMP4,BMP7,BMPR2,C1QBP,C3AR1,CALR,CAMK1D,CAPN7,CARMIL1,CARMIL2,CBLL1,CCBE1,CCL1,CCL11,CCL19,CCL2,CCL21,CCL3,CCL4,CCL5,CCL7,CCL8,CCR1,CCR2,CCR6,CCR7,CD274,CD40,CD74,CDH13,CEMIP,CGA,CIB1,CLASP1,CLASP2,CMKLR1,COL18A1,COL1A1,CORO1A,CPEB1,CPNE3,CREB3,CRK,CSF1,CSF1R,CTSH,CXCL1,CXCL10,CXCL11,CXCL13,CXCL14,CXCL16,CXCL2,CXCL3,CXCL5,CXCL6,CXCL8,CXCL9,CYR61,DAB2,DAB2IP,DAPK2,DAPK3,DDR2,DDRGK1,DIAPH1,DMTN,DOCK4,DOCK5,DOCK8,DRD1,EDN1,EDN2,EDN3,EGF,EGFR,ELP3,ENPP2,ENSG00000260272,EPB41L4B,EPB41L5,EPHA1,ETS1,F10,F2R,F2RL1,F3,F7,FADD,FAM83H,FAM89B,FBXO31,FER,FERMT3,FGF1,FGF10,FGF16,FGF18,FGF2,FGF7,FGFR1,FGFR1OP,FGR,FLNA,FLT1,FLT4,FN1,FOXC2,FOXF1,FOXO4,FSHB,GAB1,GAS6,GATA3,GCNT2,GLIPR2,GPER1,GPLD1,GPNMB,GPSM3,GRB7,GTSE1,HAS2,HBEGF,HDAC4,HDAC7,HDAC9,HGF,HIF1A,HMCN2,HMGB1,HRAS,HSPA5,HSPB1,IFNG,IGF1,IGF1R,IL12A,IL1A,IL1B,IL1R1,IL23A,IL4,IL6,IL6R,INS,INSL3,INSM1,IQGAP1,IRS2,ITGA2,ITGA2B,ITGA3,ITGA4,ITGA5,ITGAV,JAK2,JCAD,JUN,KARS,KIF20B,KITLG,LAMB1,LBP,LEF1,LGALS3,LGALS9,LGR6,LPAR1,LRRC15,LYN,MADCAM1,MAPK1,MAPK14,MAPK3,MAPRE1,MCAM,MDM2,MET,MIA3,MIEN1,MMP14,MMP9,MOSPD2,MTOR,MYADM,MYLK,MYO1C,NCKAP1L,NIPBL,NOTCH1,NOX4,NRP1,NRP2,NTF3,NTRK3,NUMB,ONECUT1,P2RX4,P2RY6,PAK1,PAK3,PDCD10,PDCD6,PDGFA,PDGFB,PDGFC,PDGFD,PDGFRB,PDPN,PF4,PF4V1,PFN1,PIK3CD,PIK3R1,PLA2G7,PLAA,PLAU,PLCG1,PLET1,PLPP3,PLVAP,PODXL,PPBP,PPM1F,PREX1,PRKCA,PRKCE,PRKD1,PRKD2,PROX1,PTAFR,PTK2,PTK2B,PTP4A1,PYCARD,RAB25,RAC1,RAC2,RAPGEF2,RARRES2,RDX,RELN,RET,RETN,RHOD,RIPOR1,RIPOR2,ROCK2,ROR2,RRAS2,RREB1,RTN4,RUFY3,S100A14,S100A7,S1PR1,SASH1,SCARB1,SDCBP,SELENOK,SELP,SEMA3A,SEMA3C,SEMA4D,SEMA5A,SEMA6A,SEMA6D,SERPINB3,SLC8A1,SMURF2,SNAI1,SNAI2,SOD2,SOX9,SPAG9,SPHK1,SPRY2,SRC,SRGAP2C,SRPX2,STX4,SUN2,SYDE1,SYNE2,TAC1,TDGF1,TEK,TERT,TGFB1,TGFB2,TGFBR1,TGFBR2,THBS1,THBS4,THY1,TIAM1,TIRAP,TNF,TNFAIP6,TNFRSF14,TNFRSF18,TNFSF14,TNFSF18,TRIM32,TRIP6,UTS2,VEGFA,VEGFB,VEGFC,VEGFD,VIL1,VTN,WNT11,WNT5A,WNT7A,XBP1,XCL1,ZC3H12A,ZNF580,ZNF609,ZNF703,ZP3	TetrapodAncestor	302.522
GO.Biological.Process	GO:0034097	response.to.cytokine	45	2.079876e-302	2.686576e-298	5.970169e-300	1.242124e+0	AANAT,ABCC2,ABCD4,ABCG4,ACKR2,ACKR3,ACKR4,ACP5,ACSL1,ACSL4,ADAM9,ADAMTS12,ADAMTS13,ADAMTS7,ADAR,ADIPOQ,ADIPOR1,ADIPOR2,AES,AFF3,AIF1,AIP,AKAP6,ALAD,ALOX15,ANKRD1,ANXA1,APOB,AQP4,ARF1,ARG1,ARHGEF2,ARID5B,ASPN,AVPR2,AXL,B3GNT2,BAD,BAG4,BBS4,BCAT2,BCL2,BCL2L1,BCLAF1,BGN,BIRC2,BIRC3,BOLA2B,BRCA1,BRWD1,BSPRY,BST2,BTK,C19orf66,CA1,CACTIN,CACYBP,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CANX,CARD14,CASP1,CASP3,CASP8,CCL1,CCL11,CCL13,CCL14,CCL15,CCL15-CCL14,CCL16,CCL17,CCL18,CCL19,CCL2,CCL21,CCL22,CCL23,CCL3,CCL3L3,CCL4,CCL4L2,CCL5,CCL7,CCL8,CCR1,CCR2,CCR3,CCR4,CCR5,CCR6,CCR7,CCR8,CCR9,CCRL2,CD14,CD27,CD274,CD300LF,CD38,CD40,CD44,CD58,CD70,CD74,CD86,CDC34,CDC42,CDC5L,CDIP1,CDK4,CDK9,CEBPA,CEBPB,CFL1,CHAD,CHI3L1,CHUK,CIB1,CIITA,CISH,CITED1,CLCF1,CLDN1,CLDN18,CMKLR1,CNTF,CNTFR,COL1A1,COL3A1,COMMD7,CORO1A,CREB1,CRHBP,CRLF2,CSF1,CSF1R,CSF2RA,CSF2RB,CSF3,CSF3R,CSNK2B,CTH,CX3CL1,CX3CR1,CXCL1,CXCL10,CXCL11,CXCL13,CXCL16,CXCL2,CXCL3,CXCL5,CXCL6,CXCL8,CXCL9,CXCR1,CXCR2,CXCR3,CXCR4,CXCR5,CXCR6,CYBA,CYP27B1,DAB2IP,DAPK1,DAPK3,DCN,DDOST,DDX41,DHX9,DOCK8,DPYSL3,DTX1,DUOX1,DUOX2,EBI3,EDA,EDA2R,EDAR,EDARADD,EDN1,EDN2,EED,EFHC2,EGR1,EIF2AK2,EIF4A2,ELOC,ENDOG,ENSG00000249624,EPO,EPOR,EPRS,EPS8,EREG,ETS1,ETV3,F3,FABP4,FAS,FASN,FER,FGF23,FGF4,FGG,FKBP1A,FLRT1,FLRT2,FLRT3,FNTB,FOS,FOSL1,FOXA2,FOXC1,FOXF1,FOXH1,FZD4,GAPDH,GAS6,GATA3,GBA,GCH1,GCLM,GFPT2,GHR,GLDC,GNAO1,GNPNAT1,GP1BA,GPD1,GPER1,GPR17,GPR35,GRB2,GREM2,GSK3A,GSS,GSTA2,HAMP,HAS2,HAX1,HCK,HCLS1,HDAC4,HIF1A,HIST1H3H,HIST1H3I,HIST1H3J,HIST2H3A,HIST2H3C,HIST2H3D,HMHB1,HNMT,HNRNPA2B1,HNRNPU,HSP90AB1,HSPA5,HSPA9,HTRA2,IFI27,IFI35,IFI6,IFIT1,IFIT2,IFIT3,IFITM1,IFITM2,IFITM3,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNAR1,IFNAR2,IFNB1,IFNE,IFNG,IFNGR1,IFNGR2,IFNK,IFNLR1,IFNW1,IGBP1,IKBKB,IKBKE,IL10,IL10RA,IL10RB,IL11RA,IL12A,IL12B,IL12RB1,IL12RB2,IL13,IL13RA1,IL13RA2,IL15,IL15RA,IL17A,IL17C,IL17F,IL17RA,IL17RB,IL17RC,IL17RD,IL17RE,IL17REL,IL18,IL18BP,IL18R1,IL18RAP,IL1A,IL1B,IL1F10,IL1R1,IL1R2,IL1RAP,IL1RAPL2,IL1RL1,IL1RL2,IL20RA,IL20RB,IL21R,IL22RA1,IL22RA2,IL23A,IL23R,IL24,IL27,IL27RA,IL2RB,IL2RG,IL31RA,IL36A,IL36B,IL36G,IL37,IL3RA,IL4,IL5,IL5RA,IL6,IL6R,IL6ST,IL7,IL7R,IL9,INPP5K,IRAK1,IRAK3,IRAK4,IRF1,IRF2,IRF3,IRF4,IRF6,IRF7,IRF8,IRF9,IRS1,IRS2,ISG15,ISG20,ITGA4,ITIH4,JAGN1,JAK2,JAK3,JARID2,JUN,JUNB,KARS,KCNJ11,KDM3A,KDM5B,KEAP1,KHSRP,KLF2,KLF4,KLF5,KLHL20,KRAS,KYNU,LAMP3,LCK,LCN2,LCP1,LEF1,LEP,LEPR,LGALS9,LIFR,LMNB1,LRAT,LRCH1,LRP8,LRRC15,LRRC19,LRRC3,LRRC3C,LRRC4,LRRC4C,LRRC66,LRRTM1,LRRTM3,LRRTM4,LRTM1,LRTM2,LTB,LTBR,MAP2K7,MAP3K14,MAP3K5,MAP4K3,MAPK1,MAPK3,MAPKAPK2,MAPKAPK3,MAT2A,MCF2,MCM2,MEFV,MID1,MIF,MKKS,MME,MPC1,MPL,MRC1,MRPL15,MSC,MSN,MST1R,MTAP,MTF2,MTHFR,MX1,MX2,MYBL2,MYLK3,MYNN,NCAM1,NCL,NEFH,NFIL3,NFKB1,NFKB2,NFYB,NGFR,NKX3-1,NKX6-1,NLRP7,NMI,NOS2,NPR2,NR5A2,NUB1,NUMBL,OAS1,OASL,OCLN,OCSTAMP,OSM,OSMR,OTUB1,OXTR,P4HB,PADI2,PAK2,PARP16,PCK1,PCK2,PDCD10,PDE12,PDE1B,PDE2A,PDGFB,PF4,PF4V1,PFKP,PGGT1B,PHB,PID1,PIGA,PIK3C3,PIK3CA,PIK3R1,PIK3R2,PITPNA,PLA2G10,PLA2G5,PLCB1,PLP2,PLSCR1,PLVAP,PML,PMM1,PNPT1,PODN,PODNL1,POU4F1,PPARGC1A,PPBP,PPP3CB,PRDM5,PRKCA,PRKCD,PRKCI,PRLR,PRPF8,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTAFR,PTGES,PTGIS,PTK2B,PTP4A3,PYCARD,PYDC1,RALA,RAP1B,RARA,RARG,RC3H1,REL,RELA,RELB,RELT,RFX2,RIF1,RIPK1,RIPK2,RIPOR2,RNASEL,RNF138,RNMT,RPL13A,RPL3,RPLP0,RPS16,RPS27A,RPS3,RPS6KA4,RPS6KA5,RSAD2,RTN4R,RTN4RL2,SAMHD1,SCGB1A1,SEC61A1,SELE,SERPINB2,SETD2,SFRP1,SHC1,SHMT1,SHMT2,SHPK,SIRT1,SKIL,SLC11A1,SLC25A5,SLC27A1,SLC30A8,SMAD4,SMAD7,SMARCA4,SNCA,SNRNP70,SNRPA1,SNX10,SOCS1,SOCS2,SOCS3,SOCS4,SOCS5,SOCS6,SOCS7,SOD1,SOD2,SOX1,SOX17,SOX9,SP100,SPOCK2,SPRY2,SRC,SRF,SRM,SRSF7,SSTR1,ST18,ST3GAL6,STAR,STAT1,STAT2,STAT4,STAT6,SYNCRIP,SYNGR1,TAF9,TALDO1,TCL1A,TCP1,TDGF1,TEX14,TFPI,TFRC,THBS1,THPO,TIMP1,TIMP2,TIMP4,TJP2,TLE4,TLR3,TMEM173,TNF,TNFRSF10A,TNFRSF10B,TNFRSF10C,TNFRSF10D,TNFRSF11A,TNFRSF11B,TNFRSF12A,TNFRSF13B,TNFRSF13C,TNFRSF14,TNFRSF17,TNFRSF18,TNFRSF19,TNFRSF1A,TNFRSF1B,TNFRSF21,TNFRSF25,TNFRSF4,TNFRSF8,TNFRSF9,TNFSF11,TNFSF12,TNFSF13,TNFSF13B,TNFSF14,TNFSF15,TNFSF18,TNFSF8,TNFSF9,TNIP2,TPR,TRADD,TRAF2,TRAF3,TRAF6,TRAFD1,TRIM21,TRIM22,TRIM25,TRIM32,TRIM34,TRIM38,TRIM5,TRIM6,TRIM62,TRIM63,TRIM68,TRIM8,TRPV1,TSLP,TUBA1B,TWISTNB,TXNDC17,TYMS,UBC,UBE2G2,UPF1,USP10,VCAM1,VEGFC,WDR35,WNT5A,XAF1,XBP1,XCL1,XCL2,XCR1,XRCC5,YBX3,YTHDC2,YY1,ZC3H12A,ZC3H15,ZFAND6,ZFP36,ZFP36L1,ZFP36L2,ZNF675	TetrapodAncestor	297.571
GO.Biological.Process	GO:0009611	response.to.wounding	46	5.207129e-302	6.726049e-298	1.462184e-299	1.288700e+0	A2M,ABHD2,ACHE,ACVRL1,ADAM15,ADAMTS13,ADIPOR2,ADORA2A,ADORA3,ADRA2A,ADRA2B,ADRA2C,AGER,AIF1,AJUBA,AK3,AKAP1,AKAP10,ALOX15,ANO6,ANXA1,ANXA5,APOA1,APOA5,APOD,APOH,AQP1,ARG1,ARHGAP35,ARHGEF19,ARRB1,ARRB2,AURKA,AXL,B4GALT1,BAX,BCL2,BCL9,BIN3,BLOC1S3,BLOC1S4,C1GALT1C1,C1QBP,C4BPB,C6orf89,CAPZA2,CAPZB,CARMIL1,CARMIL2,CASP3,CAV3,CCL2,CCM2L,CCNB1,CCR1,CCR2,CD34,CD36,CD40,CD44,CD59,CD9,CDC42,CDH3,CDK1,CDK5,CELSR1,CFLAR,CHL1,CLEC1B,COL1A1,COL1A2,COL3A1,COL5A1,CORO1B,CPB2,CPQ,CTGF,CTNNA1,CX3CL1,CX3CR1,CYP1A1,CYR61,DCBLD2,DCN,DDR1,DGKA,DGKB,DGKD,DGKE,DGKG,DGKI,DGKK,DGKQ,DGKZ,DHFR,DOCK11,DOCK6,DOCK8,DOCK9,DPYSL3,DRD2,DRD5,DSP,DST,DTNBP1,DYSF,EGFR,EHD1,EHD2,EHD3,ELK3,ENPP4,ENSG00000243696,ENSG00000259753,ENTPD2,EPB41L4B,EPO,ERBB2,ERBB4,EREG,ETS1,EYS,EZH2,F10,F11,F12,F13A1,F13B,F2,F2R,F2RL1,F2RL3,F3,F5,F7,F8,F9,FBLN1,FCER1G,FERMT3,FGF10,FGF2,FGF7,FGFR1OP2,FGFR2,FGG,FIBP,FLNA,FLRT3,FN1,FNTB,FOXF1,FUT10,FZD6,FZD7,FZD9,GAP43,GAS6,GATA2,GATA3,GATA4,GATA5,GATA6,GFAP,GGCX,GIP,GIPR,GLI3,GNA11,GNA12,GNA13,GNA14,GNA15,GNAQ,GNAS,GNG2,GP1BA,GP1BB,GP5,GP6,GP9,GPR4,GRHL3,GRIN2A,GRIN2C,GSN,H3F3A,HBB,HBD,HBE1,HBEGF,HBG1,HBG2,HDAC1,HDAC2,HHEX,HIF1A,HIST1H3H,HIST1H3I,HIST1H3J,HIST2H3A,HIST2H3C,HIST2H3D,HMG20B,HMOX1,HNF4A,HPS4,HPS5,HPSE,HRG,HSPB1,ID3,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNB1,IFRD1,IGF1,IL1A,IL24,IL6,INS,IRF1,IRF2,ISL1,ITGA2,ITGA2B,ITGA5,ITGA9,ITGB4,ITPK1,ITPR1,ITPR2,ITPR3,JAK2,JAM3,JAML,JMJD1C,JUN,KCNK2,KDM1A,KLKB1,KNG1,KRT6A,LACRT,LARGE1,LAT,LCK,LCP2,LGALS1,LGR6,LMAN1,LOX,LYN,MACF1,MAFF,MAFG,MAP2K4,MAP3K5,MAPK1,MAPK14,MAPK3,MATN2,MAX,MCAM,MDK,MERTK,METAP1,MFN2,MIA3,MICAL1,MMP12,MMRN1,MORN4,MSTN,MSX2,MTOR,MTPN,MUSTN1,MYF6,MYH9,MYL9,MYMK,MYOD1,MYOF,MYOG,NAIP,NDNF,NEFL,NF1,NINJ1,NINJ2,NLRP6,NMNAT3,NOG,NOL3,NOTCH1,NOV,NRG1,NRP1,NTRK1,NTRK3,OPRM1,P2RX2,P2RX3,P2RX4,P2RX5,P2RX6,P2RX7,P2RY1,PABPC4,PAFAH2,PAK1,PAPSS2,PATE4,PAX7,PDCD10,PDGFA,PDGFB,PDGFC,PDGFD,PDGFRB,PDPK1,PDPN,PF4,PF4V1,PHF21A,PIK3CA,PIK3CD,PIK3CG,PIK3R1,PIK3R5,PIK3R6,PKM,PLAT,PLAU,PLCG2,PLEK,PLET1,PLG,PLLP,PLSCR1,PPARA,PPARD,PRCP,PRKACA,PRKACG,PRKAR1A,PRKAR1B,PRKAR2B,PRKCA,PRKCB,PRKCD,PRKCE,PRKCG,PRKCH,PRKCQ,PROC,PROCR,PROS1,PROZ,PTK7,PTPN11,PTPN12,RAB27A,RAB5A,RAC1,RAC2,RAD51B,RAD51C,RAF1,RAP2B,RBSN,RCOR1,RHOC,RHOG,RIPOR1,RTN4RL2,S100A8,SAA1,SCARB1,SCRIB,SCUBE1,SDC4,SERPINA1,SERPINA10,SERPINA5,SERPINB2,SERPINC1,SERPIND1,SERPINE2,SERPING1,SH2B1,SH2B2,SH2B3,SLC11A1,SLC1A2,SLC1A3,SLC7A11,SMAD2,SOD1,SOX15,SOX2,SPRR3,SRC,SRF,STXBP1,SULF2,SYK,SYT11,SYT7,TEC,TFF1,TFF2,TFF3,TFPI,TFPI2,TGFB1,TGFB2,TGFBR1,TGFBR2,THBD,TIMP1,TLN1,TM4SF4,TMEFF2,TMEM110-MUSTN1,TMIGD3,TNC,TOR1A,TRIM72,TRPC3,TRPC6,TRPC7,TSPAN32,TSPO,TXK,TXN2,TYRO3,UBASH3B,VANGL2,VASH1,VAV1,VAV2,VAV3,VCL,VKORC1,VPS45,VWF,WNT1,WNT10B,WNT3A,WNT5A,WNT7A,YWHAZ,ZFP36,ZFP36L1,ZFP36L2,ZFPM1,ZFPM2	TetrapodAncestor	297.172
GO.Biological.Process	GO:0051272	positive.regulation.of.cellular.component.movement	47	5.939984e-299	7.672677e-295	1.632485e-296	1.288732e+0	AAMP,ABL1,ACKR3,ACTN4,ACVR1B,ADAM8,ADAM9,ADGRA2,ADRA2A,AGT,AIF1,AKT2,AMOTL1,ANGPT1,ANGPT4,ANO6,ANXA3,APC,APP,AQP1,ARHGEF2,ARHGEF39,ARHGEF7,ATOH8,ATP5A1,ATP8A1,BAG4,BCAR1,BCAS3,BCL2,BCL6,BDKRB1,BMP2,BMP4,BMP7,BMPR2,C1QBP,C3AR1,CALR,CAMK1D,CAPN7,CARMIL1,CARMIL2,CBLL1,CCBE1,CCL1,CCL11,CCL19,CCL2,CCL21,CCL3,CCL4,CCL5,CCL7,CCL8,CCR1,CCR2,CCR6,CCR7,CD274,CD40,CD74,CDH13,CEMIP,CFAP20,CGA,CIB1,CLASP1,CLASP2,CMKLR1,COL18A1,COL1A1,CORO1A,CPEB1,CPNE3,CREB3,CRK,CSF1,CSF1R,CTSH,CXCL1,CXCL10,CXCL11,CXCL13,CXCL14,CXCL16,CXCL2,CXCL3,CXCL5,CXCL6,CXCL8,CXCL9,CYR61,DAB2,DAB2IP,DAPK2,DAPK3,DDR2,DDRGK1,DIAPH1,DMTN,DOCK4,DOCK5,DOCK8,DRD1,DSCAM,EDN1,EDN2,EDN3,EGF,EGFR,ELP3,ENPP2,ENSG00000260272,EPB41L4B,EPB41L5,EPCAM,EPHA1,ETS1,F10,F2R,F2RL1,F3,F7,FADD,FAM83H,FAM89B,FBXO31,FER,FERMT3,FGF1,FGF10,FGF16,FGF18,FGF2,FGF7,FGFR1,FGFR1OP,FGR,FLNA,FLT1,FLT4,FN1,FOXC2,FOXF1,FOXO4,FSHB,GAB1,GAS6,GATA3,GCNT2,GLIPR2,GPER1,GPLD1,GPNMB,GPSM3,GRB7,GTSE1,HAS2,HBEGF,HDAC4,HDAC7,HDAC9,HGF,HIF1A,HMCN2,HMGB1,HRAS,HSPA5,HSPB1,IFNG,IGF1,IGF1R,IL12A,IL1A,IL1B,IL1R1,IL23A,IL4,IL6,IL6R,INS,INSL3,INSM1,IQCF1,IQGAP1,IRS2,ITGA2,ITGA2B,ITGA3,ITGA4,ITGA5,ITGAV,JAK2,JCAD,JUN,KARS,KIF20B,KITLG,LAMB1,LBP,LEF1,LGALS3,LGALS9,LGR6,LPAR1,LRRC15,LYN,MADCAM1,MAPK1,MAPK14,MAPK3,MAPRE1,MCAM,MDM2,MEGF8,MET,MIA3,MIEN1,MMP14,MMP9,MOSPD2,MTOR,MYADM,MYLK,MYO1C,NCKAP1L,NIPBL,NOS1AP,NOTCH1,NOX4,NRP1,NRP2,NTF3,NTRK3,NUMB,ONECUT1,P2RX4,P2RY6,PAK1,PAK3,PDCD10,PDCD6,PDGFA,PDGFB,PDGFC,PDGFD,PDGFRB,PDPN,PF4,PF4V1,PFN1,PGAM4,PHPT1,PIK3CD,PIK3R1,PLA2G7,PLAA,PLAU,PLCG1,PLET1,PLPP3,PLVAP,PODXL,PPBP,PPM1F,PREX1,PRKCA,PRKCE,PRKD1,PRKD2,PROX1,PTAFR,PTK2,PTK2B,PTP4A1,PYCARD,RAB25,RAC1,RAC2,RAPGEF2,RARRES2,RDX,RELN,RET,RETN,RHOD,RIPOR1,RIPOR2,RNASE10,RNF207,ROCK2,ROR2,RRAS2,RREB1,RTN4,RUFY3,S100A14,S100A7,S1PR1,SASH1,SCARB1,SDCBP,SELENOK,SELP,SEMA3A,SEMA3C,SEMA4D,SEMA5A,SEMA6A,SEMA6D,SERPINB3,SLC26A5,SLC8A1,SMURF2,SNAI1,SNAI2,SOD2,SOX9,SPAG9,SPHK1,SPOCK2,SPRY2,SRC,SRGAP2C,SRPX2,STMN1,STX4,SUN2,SYDE1,SYNE2,TAC1,TAC4,TACR3,TDGF1,TEK,TERT,TGFB1,TGFB2,TGFBR1,TGFBR2,THBS1,THBS4,THY1,TIAM1,TIRAP,TNF,TNFAIP6,TNFRSF14,TNFRSF18,TNFSF14,TNFSF18,TRIM32,TRIP6,TRPM4,TUBB2B,TWIST1,UTS2,VEGFA,VEGFB,VEGFC,VEGFD,VIL1,VTN,WNT11,WNT5A,WNT7A,XBP1,XCL1,ZC3H12A,ZNF580,ZNF609,ZNF703,ZP3	TetrapodAncestor	294.115
GO.Biological.Process	GO:0043065	positive.regulation.of.apoptotic.process	48	1.920368e-297	2.480539e-293	5.167790e-295	1.270946e+0	ABL1,ABR,ACER2,ADAM8,ADCY10,ADIPOQ,ADORA2A,AES,AGT,AGTR2,AIFM1,AIFM2,AKAP13,ALDH1A3,ANKRD1,ANO6,ANXA1,APAF1,APBB2,APC,APH1A,APH1B,ARHGEF1,ARHGEF11,ARHGEF12,ARHGEF16,ARHGEF17,ARHGEF19,ARHGEF2,ARHGEF26,ARHGEF3,ARHGEF4,ARHGEF7,ARHGEF9,ARL6IP5,ARRB1,ASCL1,ATF3,ATF4,ATF6,ATM,ATPIF1,B4GALT1,BAD,BAK1,BARD1,BAX,BCAP31,BCL10,BCL2,BCL2A1,BCL2L1,BCL2L10,BCL2L11,BCL2L13,BCL6,BCLAF1,BID,BIK,BIN1,BLID,BMP2,BMP4,BMP7,BMPR1B,BNIP3,BNIP3L,BTG1,C1QBP,C3orf38,CAMK1D,CAMK2A,CAMK2D,CAPN10,CASP1,CASP2,CASP3,CASP8,CASP9,CAV1,CCAR2,CCK,CCL3,CCL5,CD274,CD40,CDC34,CDC42,CDK19,CDK4,CDK5,CDK5R1,CDKN2A,CHEK2,CIDEB,CLIP3,CNR1,COL18A1,COL4A3,CRADD,CREB1,CRYBA1,CTGF,CTLA4,CTNNA1,CTNNB1,CTNNBL1,CTSC,CTSH,CTSZ,CYCS,CYP1B1,CYR61,DAB2IP,DAP,DAPK1,DAPK3,DCUN1D3,DDX3X,DEDD2,DFFA,DFNA5,DHODH,DKKL1,DLC1,DNAJA1,DNM1L,DNM2,DUSP1,DUSP6,DYNLL1,DYNLL2,E2F1,ECSCR,ECT2,EGLN3,EIF2AK3,EIF2B5,ENDOG,EPHA7,ERBB4,ERCC3,F2R,F3,FADD,FAF1,FAM162A,FAS,FASLG,FBXO18,FBXW7,FGD1,FGD2,FGD3,FGD4,FIS1,FLCN,FOSL1,FOXA1,FOXO1,FZD9,G0S2,GADD45A,GADD45B,GADD45G,GAL,GAPDH,GNA13,GPER1,GPLD1,GRAMD4,GRIK2,GRIK5,GRIN1,GRIN2A,GSK3A,GSN,GZMA,HDAC4,HIP1,HIP1R,HMGA2,HMGB1,HMGCR,HMOX1,HPGD,HRG,HRK,HSF1,HTRA2,HTT,IAPP,ID3,IDO1,IFI27,IFIT2,IFNB1,IFNG,IFT57,IGF2R,IL10,IL12A,IL12B,IL19,IL20RA,IL6,INCA1,ING3,ING5,INHBA,INHBB,INPP5D,ITGA1,ITGB1,ITM2C,ITSN1,JAK2,JMY,JUN,KALRN,KCNMA1,KLF11,KNG1,LATS1,LATS2,LCK,LDHA,LEP,LGALS13,LGALS14,LGALS16,LGALS9,LPAR1,LTBR,LTK,LYN,MAP2K4,MAP2K6,MAP3K10,MAP3K11,MAP3K5,MAP3K9,MAPK8,MAPK9,MAPT,MCF2,MCF2L,MEF2C,MELK,MFF,MLLT11,MMP9,MSX1,MSX2,MTCH1,MTCH2,MUL1,MYB,MYBBP1A,MYBL2,MYC,NCK1,NCK2,NCOA1,NCSTN,NET1,NEURL1,NEUROD1,NF1,NFATC4,NFKBID,NGEF,NGF,NGFR,NKX3-1,NLRC4,NLRP1,NLRP2,NMT1,NOD1,NOTCH1,NOX4,NQO1,NQO2,NR4A3,NSMAF,NTRK3,NTSR1,NUPR1,OBSCN,OSGIN1,OSM,P2RX7,PAK2,PAK3,PANO1,PARK7,PAWR,PDCD1,PDCD2,PDCD5,PDCD6,PDGFRB,PDIA3,PEA15,PIAS4,PIDD1,PIK3CD,PIN1,PINK1,PLA2G6,PLEKHF1,PLEKHG2,PLEKHG5,PMAIP1,PML,PNMA1,PNMA2,PNMA5,POU4F1,PPARG,PPARGC1A,PPIF,PPM1F,PPP1R13B,PPP2R1B,PPP3CC,PPP3R1,PRELID1,PREX1,PRKCD,PRKCI,PRKDC,PRKRA,PSEN1,PSEN2,PSENEN,PTEN,PTGIS,PTN,PTPA,PXT1,PYCARD,RAC1,RAD9A,RAPGEF2,RAPSN,RARB,RARG,RASGRF2,RASSF2,RBCK1,RBM5,REST,RET,RGCC,RIPK1,RIPK2,RIPK3,RNPS1,ROBO1,RPL11,RPS27A,RPS27L,RPS3,RPS6,RPS6KA2,RPS7,RRP1B,RYBP,S100A8,S100A9,S100B,SAP18,SCIN,SCRIB,SEPT4,SERINC3,SFN,SFPQ,SFRP1,SFRP2,SFRP4,SIAH1,SIK1,SIRT1,SIRT2,SKIL,SLC9A1,SLC9A3R1,SLIT2,SMPD1,SNCA,SOD1,SOS1,SOX4,SOX7,SPOP,SQSTM1,SRC,SRPK2,SRPX,ST18,STK17A,STK17B,STK4,STPG1,SUDS3,SYCE3,TFAP2A,TFAP2B,TFDP2,TGFB1,TGFB2,TGFBR1,TGM2,THBS1,TIA1,TIAM1,TIAM2,TIGAR,TIMP3,TLR3,TNF,TNFAIP8,TNFRSF10A,TNFRSF10B,TNFRSF12A,TNFRSF8,TNFSF10,TNFSF12,TNFSF15,TOP2A,TP53,TP53BP2,TP53INP1,TP63,TP73,TPD52L1,TRADD,TRAF2,TRAF6,TRAF7,TRIM35,TRIM39,TRIO,TRPV1,TSPO,TXNIP,UBC,UBE2M,UNC13B,UNC5C,USP17L30,VAV1,VAV2,VAV3,VCP,VDR,WDR35,WNT10B,WNT11,WNT3A,WNT5A,WWOX,XDH,YWHAB,YWHAE,YWHAG,YWHAH,YWHAZ,ZBTB16,ZC3H12A,ZC3H8,ZMAT3,ZNF205,ZNF346,ZNF622,ZSWIM2	TetrapodAncestor	292.605
GO.Biological.Process	GO:0002683	negative.regulation.of.immune.system.process	49	4.270448e-297	5.516138e-293	1.125742e-294	1.351545e+0	A2M,ABR,ADA,ADAR,ADCYAP1,ADGRF5,ADIPOQ,ADORA1,ADORA2A,ALOX15,AMBP,ANGPT1,ANXA1,APOA1,APOA2,APOD,ARG1,ARG2,ARRB2,ATM,AXL,BANK1,BCL10,BCL6,BCR,BMP4,BMP5,BPI,BPIFB1,BST2,BTK,C1QBP,C1QC,C4BPA,C4BPB,C5,CACTIN,CARTPT,CASP3,CCL2,CCL21,CCL28,CCL3,CCR2,CD14,CD274,CD300A,CD300LF,CD46,CD55,CD59,CD74,CD86,CD96,CDC73,CDK6,CEBPB,CIB1,CLDN18,CLEC12B,CLEC4G,CNR1,CNR2,COL3A1,CR1,CRK,CTLA4,CTNNB1,CUL4A,CYP19A1,DAB2IP,DCST1,DDT,DLG1,DLG5,DLL1,DRD2,DTX1,DUSP10,DUSP22,DUSP3,EIF2AK2,ELF1,ERBB2,EZR,F2RL1,FADD,FAM19A3,FAM3A,FAS,FBXO7,FCER1G,FER,FOXF1,FOXJ1,FOXP3,FSTL3,GABPA,GAL,GATA2,GLI3,GNRH1,GPAM,GPATCH3,GPER1,GPNMB,GPR17,GPR171,GPR18,GPR55,GPR68,GREM1,HAVCR2,HES1,HES5,HIST1H4J,HIST1H4K,HIST1H4L,HIST2H4B,HIST4H4,HLX,HMGB1,HMGB3,HMOX1,HSPA9,HTRA1,IDO1,IFIT1,IFNA2,IFNB1,IFNL1,IHH,IL10,IL12B,IL13RA2,IL1RL1,IL2,IL20RB,IL27RA,IL31RA,IL33,IL4,IL7R,INHA,INHBA,INPP5D,INS,IRAK3,IRF1,IRF4,ITCH,ITPKB,JAK3,KITLG,KLF13,KLRK1,LAX1,LDLR,LEO1,LGALS3,LGALS9,LGR4,LILRA4,LILRB2,LILRB4,LOXL3,LPXN,LRCH1,LRRC14,LRRC17,LRRC32,LST1,LY96,LYN,MAD1L1,MAFB,MEIS1,MEIS2,MERTK,MIF,MILR1,MIXL1,MMP12,MMP28,MUL1,MYC,NBL1,NDFIP1,NF1,NFKBID,NLRC3,NLRC5,NLRP6,NLRX1,NME1,NME2,NMI,NOTCH1,NOV,NPY5R,NR1D1,NR1H2,NR1H3,PADI2,PAF1,PAG1,PARP14,PAWR,PCBP2,PDCD1,PDCD1LG2,PDE5A,PDPK1,PELI1,PF4,PGLYRP1,PGLYRP2,PGLYRP3,PHPT1,PIK3R1,PKN1,PLA2G2D,PLA2G2F,PLCB1,PLCL2,PPARG,PPP3CB,PRDM1,PRKAR1A,PRKDC,PRMT1,PSMB4,PTGER4,PTK2B,PTPN22,PTPRJ,PTPRS,PVRIG,RAB7B,RARA,RC3H1,RHBDD3,RIOK3,RIPOR2,RNF125,RNF26,SAMSN1,SARM1,SCGB1A1,SCRIB,SDC4,SEC14L1,SERPINB4,SERPINB9,SERPING1,SFRP1,SLA2,SLIT2,SMAD7,SMPDL3B,SOCS5,SOCS6,SOX11,SOX9,SPINK5,SPN,STAP1,STAT6,TAPBPL,TARBP2,TARM1,TBC1D10C,TGFB1,TGFB2,THBS1,THOC1,THY1,TICAM1,TICAM2,TIGIT,TJP2,TKFC,TLR3,TLR4,TLR6,TLR9,TMBIM6,TMEM131L,TMEM176A,TMEM176B,TMEM178A,TNF,TNFAIP3,TNFAIP8L2,TNFRSF13B,TNFRSF14,TNFRSF21,TNFSF18,TRAF3IP1,TRAFD1,TRIB1,TSC22D4,TSPAN32,TSPAN6,TYRO3,UBASH3A,UBASH3B,UBQLN1,UFD1,VSIG4,VTCN1,WDR61,XCL1,ZBTB16,ZC3H12A,ZC3H8,ZFP36,ZFP36L1,ZFPM1,ZNF675	TetrapodAncestor	292.258
GO.Biological.Process	GO:0010942	positive.regulation.of.cell.death	50	2.996847e-295	3.871027e-291	7.742055e-293	1.258092e+0	ABL1,ABR,ACER2,ACOX2,ADAM8,ADCY10,ADIPOQ,ADORA2A,AES,AGT,AGTR2,AIFM1,AIFM2,AKAP13,ALDH1A3,ANKRD1,ANO6,ANXA1,APAF1,APBB2,APC,APH1A,APH1B,ARHGEF1,ARHGEF11,ARHGEF12,ARHGEF16,ARHGEF17,ARHGEF19,ARHGEF2,ARHGEF26,ARHGEF3,ARHGEF4,ARHGEF7,ARHGEF9,ARL6IP5,ARRB1,ASCL1,ATF3,ATF4,ATF6,ATM,ATPIF1,AXIN2,B4GALT1,BAD,BAK1,BARD1,BAX,BCAP31,BCL10,BCL2,BCL2A1,BCL2L1,BCL2L10,BCL2L11,BCL2L13,BCL6,BCLAF1,BID,BIK,BIN1,BLID,BMP2,BMP4,BMP7,BMPR1B,BNIP3,BNIP3L,BTG1,C1QBP,C3orf38,CALCR,CAMK1D,CAMK2A,CAMK2D,CAPN10,CASP1,CASP2,CASP3,CASP8,CASP9,CAV1,CCAR2,CCK,CCL3,CCL5,CD274,CD36,CD40,CDC34,CDC42,CDK19,CDK4,CDK5,CDK5R1,CDKN1A,CDKN1B,CDKN2A,CHEK2,CIDEB,CLIP3,CLU,CNR1,COL18A1,COL4A3,CRADD,CREB1,CRYBA1,CTGF,CTLA4,CTNNA1,CTNNB1,CTNNBL1,CTSC,CTSH,CTSZ,CYCS,CYP1B1,CYR61,CYSLTR2,DAB2IP,DAP,DAPK1,DAPK3,DAXX,DCUN1D3,DDIT4,DDX3X,DEDD2,DFFA,DFNA5,DHODH,DKK1,DKKL1,DLC1,DNAJA1,DNM1L,DNM2,DNMT3A,DUSP1,DUSP6,DYNLL1,DYNLL2,E2F1,ECSCR,ECT2,EFNB2,EGLN3,EGR1,EIF2AK3,EIF2B5,ELK1,ENDOG,EPHA7,ERBB4,ERCC3,F2R,F3,FADD,FAF1,FAM162A,FAS,FASLG,FBXO18,FBXW7,FGD1,FGD2,FGD3,FGD4,FIS1,FLCN,FOS,FOSL1,FOXA1,FOXO1,FZD9,G0S2,GADD45A,GADD45B,GADD45G,GAL,GAPDH,GNA13,GPER1,GPLD1,GRAMD4,GRIK2,GRIK5,GRIN1,GRIN2A,GSK3A,GSN,GZMA,HBA1,HBA2,HBB,HDAC4,HEBP2,HIP1,HIP1R,HMGA2,HMGB1,HMGCR,HMOX1,HP,HPGD,HRG,HRK,HSF1,HTRA2,HTT,IAPP,ID3,IDO1,IFI27,IFIT2,IFNB1,IFNG,IFT57,IGF2R,IL10,IL12A,IL12B,IL19,IL20RA,IL6,INCA1,ING3,ING5,INHBA,INHBB,INPP5D,ITGA1,ITGAM,ITGB1,ITM2C,ITSN1,JAK2,JMY,JUN,KALRN,KATNB1,KCNK2,KCNMA1,KLF11,KNG1,LATS1,LATS2,LCK,LDHA,LEP,LGALS13,LGALS14,LGALS16,LGALS9,LPAR1,LRP1,LRRK2,LTBR,LTK,LYN,MAP2K4,MAP2K6,MAP3K10,MAP3K11,MAP3K5,MAP3K9,MAPK8,MAPK9,MAPT,MARK4,MCF2,MCF2L,MEF2C,MELK,MFF,MLLT11,MMP3,MMP9,MSX1,MSX2,MTCH1,MTCH2,MTOR,MUL1,MYB,MYBBP1A,MYBL2,MYC,MYCN,NCK1,NCK2,NCOA1,NCSTN,NET1,NEURL1,NEUROD1,NF1,NFATC4,NFKBID,NGEF,NGF,NGFR,NKX3-1,NLRC4,NLRP1,NLRP2,NMT1,NOD1,NOTCH1,NOX4,NQO1,NQO2,NR4A3,NSMAF,NTRK1,NTRK3,NTSR1,NUPR1,OBSCN,OSGIN1,OSM,P2RX7,PAK2,PAK3,PANO1,PARK7,PARP1,PAWR,PDCD1,PDCD2,PDCD5,PDCD6,PDGFRB,PDIA3,PEA15,PHB,PIAS4,PICALM,PIDD1,PIK3CD,PIN1,PINK1,PLA2G6,PLEKHF1,PLEKHG2,PLEKHG5,PMAIP1,PML,PNMA1,PNMA2,PNMA5,POU4F1,PPARG,PPARGC1A,PPIF,PPM1F,PPP1R13B,PPP2R1B,PPP3CC,PPP3R1,PRELID1,PREX1,PRKCD,PRKCI,PRKDC,PRKRA,PRODH,PSEN1,PSEN2,PSENEN,PTEN,PTGIS,PTN,PTPA,PXT1,PYCARD,RAC1,RAD9A,RAPGEF2,RAPSN,RARB,RARG,RASGRF2,RASSF2,RBCK1,RBM5,REST,RET,RGCC,RIPK1,RIPK2,RIPK3,RNPS1,ROBO1,RPL11,RPS27A,RPS27L,RPS3,RPS6,RPS6KA2,RPS7,RRP1B,RYBP,S100A8,S100A9,S100B,SAP18,SAP30BP,SCIN,SCRIB,SEPT4,SERINC3,SFN,SFPQ,SFRP1,SFRP2,SFRP4,SIAH1,SIK1,SIRT1,SIRT2,SKIL,SLC9A1,SLC9A3R1,SLIT2,SMPD1,SNCA,SOD1,SOS1,SOX4,SOX7,SPOP,SQSTM1,SRC,SRPK2,SRPX,ST18,STK17A,STK17B,STK4,STPG1,SUDS3,SYCE3,TFAP2A,TFAP2B,TFDP2,TGFB1,TGFB2,TGFBR1,TGM2,THBS1,TIA1,TIAM1,TIAM2,TIGAR,TIMP3,TLR3,TLR4,TLR6,TNF,TNFAIP8,TNFRSF10A,TNFRSF10B,TNFRSF12A,TNFRSF8,TNFSF10,TNFSF12,TNFSF15,TOP2A,TP53,TP53BP2,TP53INP1,TP63,TP73,TPD52L1,TRADD,TRAF2,TRAF6,TRAF7,TRIM13,TRIM35,TRIM39,TRIO,TRPV1,TSPO,TXNIP,UBC,UBE2M,UCP2,UNC13B,UNC5C,USP17L30,VAV1,VAV2,VAV3,VCP,VDR,WDR35,WNT10B,WNT11,WNT3A,WNT5A,WWOX,XDH,YWHAB,YWHAE,YWHAG,YWHAH,YWHAZ,ZBTB16,ZC3H12A,ZC3H8,ZMAT3,ZNF205,ZNF346,ZNF622,ZNF746,ZSWIM2	TetrapodAncestor	290.412
GO.Biological.Process	GO:0048514	blood.vessel.morphogenesis	51	3.685132e-291	4.760085e-287	9.333500e-289	1.287521e+0	AAMP,ACKR3,ACVRL1,ADAM15,ADAM8,ADAMTS9,ADGRA2,ADGRG1,ADIPOR2,ADM2,AGGF1,AMOT,ANGPT1,ANGPT2,ANGPT4,ANGPTL4,ANPEP,APOB,APOD,APOE,APOLD1,ARHGAP22,ARHGAP24,ARID2,ATPIF1,B4GALT1,BAK1,BAX,BCAS3,BMP4,BMPER,BMPR1A,BMPR2,C1GALT1,CALCRL,CAV1,CCBE1,CCL2,CCM2,CD34,CDC42,CDH13,CDH2,CHD7,CIB1,CITED1,COL15A1,COL18A1,COL3A1,COL8A1,COL8A2,CSPG4,CTGF,CTNNB1,CUL7,CX3CL1,CXCL8,CXCR3,CYP1B1,CYR61,DAB2IP,DLL1,DLL4,E2F7,E2F8,ECSCR,EDN1,EFNA1,EFNB2,EGF,EGFL7,EGR3,EIF2AK3,ELK3,ENG,ENPEP,ENSG00000259753,EPAS1,EPGN,EPHA1,EPHA2,EPHB1,EPHB2,EPHB3,EPHB4,ERAP1,EREG,ESM1,ETS1,EYA1,FGF1,FGF10,FGF18,FGF2,FGF6,FGF9,FGFR1,FGFR2,FLT1,FLT4,FMNL3,FN1,FOXC1,FOXC2,FOXF1,FOXH1,FOXN1,FZD4,FZD5,FZD8,GAB1,GBX2,GDF2,GJC1,GNA13,GPLD1,GPR4,GREM1,HAND1,HAND2,HAS2,HDAC7,HEG1,HES1,HEY1,HEY2,HHEX,HIF1A,HIF3A,HMOX1,HOXA1,HPGD,HPSE,HRG,HS6ST1,HSPG2,ID1,IHH,IL18,ITGA5,ITGAV,ITGB1,JAG1,JAM3,JMJD6,JUN,JUNB,KLF5,KRIT1,LAMA5,LEF1,LEMD3,LEP,LEPR,LOX,LOXL2,LRP1,LRP5,MAPK14,MCAM,MEIS1,MEOX2,MFGE8,MMP14,MMP19,MMRN2,MYDGF,MYH9,MYLK,MYO1E,MYOCD,NAA15,NCL,NDNF,NF1,NFATC4,NKX2-5,NOG,NOS3,NOTCH1,NOTCH3,NOTCH4,NOV,NOX5,NPRL3,NR4A1,NRP1,NRP2,NTRK2,NUS1,OTULIN,OVOL2,PAXIP1,PDCD10,PDCD6,PDCL3,PDGFA,PDGFRB,PIK3CA,PIK3CG,PIK3R6,PITX2,PKD2,PKNOX1,PLCD3,PLXDC1,PLXND1,PRCP,PRDM1,PRKCA,PRKD1,PRKD2,PRKX,PROK1,PROK2,PROX1,PRRX1,PTEN,PTK2,PTK2B,PTPRB,QKI,RAMP1,RAMP2,RAPGEF3,RASA1,RASIP1,RBPJ,RNF213,ROBO1,ROBO4,RSPO3,S100A7,S1PR1,SAT1,SCG2,SEC24B,SEMA3E,SEMA4A,SEMA5A,SETD2,SFRP2,SGPL1,SH2D2A,SHB,SHC1,SIRT1,SLC12A6,SLIT2,SMAD7,SMO,SOS1,SOX17,SOX18,SOX4,SPI1,SPRED1,SRF,SRPK2,SRPX2,STAB2,STK4,STRA6,SYK,T,TAL1,TBX1,TBX2,TBX20,TBX5,TCF21,TDGF1,TEAD2,TEK,TFAP2B,TGFB1,TGFB2,TGFBI,TGFBR1,TGFBR2,THBS1,THSD7A,THY1,TIE1,TIPARP,TMEM100,TMEM2,TMPRSS6,TNFRSF12A,TNFSF12,TNNI3,TSPAN12,TYMP,UBP1,UNC5B,VASH1,VAV2,VAV3,VEGFA,VEGFB,VEGFC,VEGFD,VEZF1,VHLL,WARS,WARS2,WASF2,WNT11,WNT7A,WNT7B,XBP1,ZC3H12A,ZFP36L1,ZFPM2,ZMIZ1	TetrapodAncestor	286.322
GO.Biological.Process	GO:2000147	positive.regulation.of.cell.motility	52	3.702185e-291	4.782112e-287	9.196370e-289	1.287511e+0	AAMP,ABL1,ACKR3,ACTN4,ACVR1B,ADAM8,ADAM9,ADGRA2,ADRA2A,AGT,AIF1,AKT2,AMOTL1,ANGPT1,ANGPT4,ANO6,ANXA3,APC,APP,AQP1,ARHGEF2,ARHGEF39,ARHGEF7,ATOH8,ATP5A1,ATP8A1,BAG4,BCAR1,BCAS3,BCL2,BDKRB1,BMP2,BMP4,BMP7,BMPR2,C1QBP,C3AR1,CALR,CAMK1D,CAPN7,CARMIL1,CARMIL2,CBLL1,CCBE1,CCL1,CCL11,CCL19,CCL2,CCL21,CCL3,CCL4,CCL5,CCL7,CCL8,CCR1,CCR2,CCR6,CCR7,CD274,CD40,CD74,CDH13,CEMIP,CFAP20,CGA,CIB1,CLASP1,CLASP2,CMKLR1,COL18A1,COL1A1,CORO1A,CPEB1,CPNE3,CREB3,CRK,CSF1,CSF1R,CTSH,CXCL1,CXCL10,CXCL11,CXCL13,CXCL14,CXCL16,CXCL2,CXCL3,CXCL5,CXCL6,CXCL8,CXCL9,CYR61,DAB2,DAB2IP,DAPK2,DAPK3,DDR2,DDRGK1,DIAPH1,DMTN,DOCK4,DOCK5,DOCK8,DRD1,EDN1,EDN2,EDN3,EGF,EGFR,ELP3,ENPP2,ENSG00000260272,EPB41L4B,EPB41L5,EPCAM,EPHA1,ETS1,F10,F2R,F2RL1,F3,F7,FADD,FAM83H,FAM89B,FBXO31,FER,FERMT3,FGF1,FGF10,FGF16,FGF18,FGF2,FGF7,FGFR1,FGFR1OP,FGR,FLNA,FLT1,FLT4,FN1,FOXC2,FOXF1,FOXO4,FSHB,GAB1,GAS6,GATA3,GCNT2,GLIPR2,GPER1,GPLD1,GPNMB,GPSM3,GRB7,GTSE1,HAS2,HBEGF,HDAC4,HDAC7,HDAC9,HGF,HIF1A,HMCN2,HMGB1,HRAS,HSPA5,HSPB1,IFNG,IGF1,IGF1R,IL12A,IL1A,IL1B,IL1R1,IL23A,IL4,IL6,IL6R,INS,INSL3,INSM1,IQCF1,IQGAP1,IRS2,ITGA2,ITGA2B,ITGA3,ITGA4,ITGA5,ITGAV,JAK2,JCAD,JUN,KARS,KIF20B,KITLG,LAMB1,LBP,LEF1,LGALS3,LGALS9,LGR6,LPAR1,LRRC15,LYN,MADCAM1,MAPK1,MAPK14,MAPK3,MAPRE1,MCAM,MDM2,MET,MIA3,MIEN1,MMP14,MMP9,MOSPD2,MTOR,MYADM,MYLK,MYO1C,NCKAP1L,NIPBL,NOTCH1,NOX4,NRP1,NRP2,NTF3,NTRK3,NUMB,ONECUT1,P2RX4,P2RY6,PAK1,PAK3,PDCD10,PDCD6,PDGFA,PDGFB,PDGFC,PDGFD,PDGFRB,PDPN,PF4,PF4V1,PFN1,PGAM4,PHPT1,PIK3CD,PIK3R1,PLA2G7,PLAA,PLAU,PLCG1,PLET1,PLPP3,PLVAP,PODXL,PPBP,PPM1F,PREX1,PRKCA,PRKCE,PRKD1,PRKD2,PROX1,PTAFR,PTK2,PTK2B,PTP4A1,PYCARD,RAB25,RAC1,RAC2,RAPGEF2,RARRES2,RDX,RELN,RET,RETN,RHOD,RIPOR1,RIPOR2,RNASE10,ROCK2,ROR2,RRAS2,RREB1,RTN4,RUFY3,S100A14,S100A7,S1PR1,SASH1,SCARB1,SDCBP,SELENOK,SELP,SEMA3A,SEMA3C,SEMA4D,SEMA5A,SEMA6A,SEMA6D,SERPINB3,SLC26A5,SLC8A1,SMURF2,SNAI1,SNAI2,SOD2,SOX9,SPAG9,SPHK1,SPOCK2,SPRY2,SRC,SRGAP2C,SRPX2,STX4,SUN2,SYDE1,SYNE2,TAC1,TAC4,TACR3,TDGF1,TEK,TERT,TGFB1,TGFB2,TGFBR1,TGFBR2,THBS1,THBS4,THY1,TIAM1,TIRAP,TNF,TNFAIP6,TNFRSF14,TNFRSF18,TNFSF14,TNFSF18,TRIM32,TRIP6,TWIST1,UTS2,VEGFA,VEGFB,VEGFC,VEGFD,VIL1,VTN,WNT11,WNT5A,WNT7A,XBP1,XCL1,ZC3H12A,ZNF580,ZNF609,ZNF703,ZP3	TetrapodAncestor	286.32
GO.Biological.Process	GO:1902105	regulation.of.leukocyte.differentiation	53	1.470703e-290	1.899707e-286	3.584353e-288	1.407588e+0	ABL1,ACIN1,ADA,ADAM8,ADIPOQ,AGER,ANXA1,AP3D1,ATP11C,ATP6AP1,AXL,BAD,BCL6,BGLAP,BMP4,BRAF,BTK,C1QC,CA2,CAMK4,CARD11,CARTPT,CASP8,CBFB,CCL19,CCL3,CCR1,CD101,CD2,CD27,CD28,CD46,CD74,CD80,CD83,CD86,CDK6,CEBPB,CLDN18,CR1,CREB1,CSF1,CTLA4,CTNNB1,CUL4A,CYP26B1,DROSHA,DTX1,DUSP10,ERBB2,ESRRA,FADD,FANCA,FAS,FBXO7,FLT3LG,FOS,FOXJ1,FOXN1,FOXP3,FSHB,FSHR,FSTL3,GAS6,GATA2,GATA3,GLI2,GLI3,GNAS,GPR55,GPR68,HAX1,HCLS1,HLX,HMGB1,HMGB3,IFNA2,IFNB1,IFNG,IFNL1,IHH,IKZF3,IL12A,IL12B,IL12RB1,IL15,IL17A,IL18,IL1RL2,IL2,IL20,IL23A,IL23R,IL27,IL34,IL36B,IL4,IL5,IL6,IL7,IL7R,INHA,INHBA,INPP5D,IRF1,IRF4,IRF7,ITPKB,JAK3,JUN,KITLG,KLF10,LEF1,LGALS9,LHCGR,LIF,LILRB2,LILRB4,LOXL3,LRRC17,LYN,MAFB,METTL3,MMP14,MTOR,MYB,MYC,NCKAP1L,NDFIP1,NF1,NFAM1,NFATC2,NFKBID,NME1,NME2,OCSTAMP,PCID2,PF4,PGLYRP1,PGLYRP2,PGLYRP3,PIK3R1,PIK3R6,PNP,POU4F1,PPARGC1B,PPP2R3C,PRDM1,PRELID1,PRKCA,PRKCZ,RAG1,RARA,RASGRP1,RASSF2,RB1,RC3H1,RIPK1,RIPK2,RNF41,ROR2,RUNX1,SART1,SASH3,SFRP1,SHB,SIGLEC15,SLC46A2,SLC9B2,SMAD7,SOCS1,SOCS5,SOD1,SOS1,SOX13,SPINK5,SYK,TAL1,TESC,TESPA1,TFE3,TGFB1,TGFBR2,TJP2,TLR3,TLR4,TLR9,TMEM131L,TMEM176A,TMEM176B,TMEM178A,TMEM64,TNF,TNFRSF18,TNFSF11,TNFSF18,TNFSF9,TRAF6,TRIB1,UBASH3B,VNN1,XBP1,ZAP70,ZBTB1,ZBTB16,ZBTB7B,ZC3H8,ZEB1,ZFP36L1,ZFP36L2,ZFPM1,ZMIZ1,ZNF675,ZNF683	TetrapodAncestor	285.721
GO.Biological.Process	GO:0043066	negative.regulation.of.apoptotic.process	54	8.267584e-286	1.067924e-281	1.977637e-283	1.220427e+0	AAMDC,AARS,AATF,ABL1,ACAA2,ACKR3,ADA,ADAM8,ADAMTS20,ADAR,ADCYAP1,ADNP,ADORA1,ADORA2A,AGAP2,AGO4,AHI1,AIF1,AIPL1,AKR1B1,AKT2,ALB,ALKBH1,AMBRA1,AMIGO2,ANGPT1,ANGPT4,ANGPTL4,ANXA1,ANXA4,ANXA5,APBB2,API5,APIP,APOE,APOH,AQP1,AR,ARAF,ARF4,ARG2,ARHGDIA,ARHGEF2,ARL6IP1,ARNT2,ARRB1,ARRB2,ASCL1,ASIC2,ASNS,ATAD3A,ATF5,ATG5,ATOH1,AURKA,AURKB,AVP,AXL,BABAM2,BAD,BAG1,BAG4,BAG6,BARD1,BARHL1,BAX,BCL10,BCL11B,BCL2,BCL2A1,BCL2L1,BCL2L10,BCL2L12,BCL2L2,BCL2L2-PABPN1,BCL3,BCL6,BDKRB2,BDNF,BECN1,BFAR,BID,BIRC2,BIRC3,BIRC5,BIRC6,BMP4,BMP5,BMP7,BNIP1,BNIP3,BNIP3L,BRAF,BRCA1,BTC,BTG2,C8orf4,CAMK1D,CARD14,CARD16,CASP2,CASP3,CASP8,CAST,CAT,CAV1,CBL,CBX4,CCAR2,CCL19,CCL2,CCL21,CCL5,CCND2,CCR7,CD27,CD38,CD44,CD59,CD74,CDC73,CDK1,CDKN1A,CDKN1B,CDKN2D,CEBPB,CFDP1,CFL1,CFLAR,CHD8,CHL1,CHST11,CIAPIN1,CIB1,CIDEA,CITED1,CITED2,CLCF1,CLN3,CLU,CNTF,CNTFR,COL2A1,CORO1A,CPEB4,CREB3,CREB3L1,CRYAA,CRYAB,CSF1R,CSNK2A1,CTH,CTNNA1,CTNNB1,CTSH,CTTN,CX3CL1,CX3CR1,CYR61,DAB2,DAD1,DAPK1,DDB1,DDIAS,DDRGK1,DDX3X,DFFA,DHCR24,DHRS2,DKK1,DLL1,DNAJA1,DNAJB6,DOCK8,DPEP1,DRAXIN,DSTYK,DUSP1,DYRK3,EDN1,EDNRB,EEF2K,EFNA1,EGFR,EGR3,EIF2AK2,ELL3,EN1,EPCAM,EPO,ERBB4,ERC1,ERCC5,EYA1,EYA2,EYA3,EYA4,F2R,FABP1,FADD,FAIM2,FAM129B,FAS,FASLG,FCER1G,FCMR,FFAR4,FGF10,FGF20,FGF21,FGF4,FGFR2,FGG,FHL2,FIGNL1,FLNA,FLT3LG,FLT4,FMN2,FOXC1,FOXC2,FOXE3,FOXO1,FXN,FZD3,FZD9,GABRA5,GABRB2,GABRB3,GAS6,GATA3,GATA6,GCLM,GDF5,GDNF,GFRAL,GHSR,GLI2,GLI3,GLO1,GNRH1,GOLPH3,GPAM,GREM1,GRIK2,GRIN1,GRINA,GRK5,GSTP1,HAND2,HAX1,HCK,HCLS1,HDAC1,HDAC2,HDAC3,HERPUD1,HEY2,HGF,HIF1A,HIGD1A,HIGD2A,HIP1R,HIPK2,HMGA2,HMGB2,HMGCR,HMGN5,HMOX1,HNF1B,HNRNPK,HPN,HRAS,HSF1,HSH2D,HSP90AB1,HSP90B1,HSPA5,HSPA9,HSPB1,HSPB6,HSPH1,HTR2B,HTRA2,HTT,HYOU1,HYPK,ID1,IDO1,IER3,IFI6,IFIT3,IGBP1,IGF1,IGF1R,IHH,IKBKB,IL10,IL13,IL19,IL1A,IL1B,IL2,IL2RB,IL31RA,IL4,IL6,IL6ST,IL7,ING2,INS,INSL6,IRAK1,IRF7,IRS2,ISL1,ITCH,ITGA5,ITGAV,ITGB1,ITPKB,ITSN1,IVNS1ABP,JAK2,JAK3,JUN,KDM1A,KDM2B,KIFAP3,KITLG,KLF4,KLHL20,KRAS,KRIT1,LACRT,LAMP3,LEF1,LEP,LGALS3,LGMN,LHX4,LIG4,LIMS2,LMNA,LRP1,LRP6,LRRK2,LTK,MAD2L1,MAEA,MAEL,MAG,MALT1,MAP2K4,MAP3K12,MAP4K4,MAPK8,MAPK8IP1,MDK,MDM2,MDM4,MECP2,MEF2C,MEIS3,MERTK,MICAL1,MIEN1,MIF,MMP9,MNT,MPO,MPV17L,MRE11,MSH2,MSX1,MSX2,MTDH,MTOR,MUC1,MYC,MYDGF,MYO18A,MYOCD,NAA15,NAA16,NAA35,NAA38,NAIP,NANOS3,NAT8,NCKAP1L,NDNF,NDUFS3,NEFL,NES,NEUROD1,NFKB1,NGF,NGFR,NKX2-5,NKX2-6,NKX3-2,NLE1,NLRC4,NME2,NME5,NOC2L,NOG,NOL3,NOS3,NOTCH1,NOTCH2,NPM1,NPY5R,NQO1,NR1H4,NR4A2,NR4A3,NRP1,NTF3,NTF4,NTRK1,NTRK2,NTSR1,NUAK2,NUGGC,NUP62,OGG1,OPA1,OSR1,OXR1,PAFAH2,PAK2,PAK5,PALB2,PARK7,PAX2,PAX4,PAX7,PAX8,PCGF2,PCID2,PDCD1,PDCD10,PDE3A,PDGFRB,PDPK1,PDPN,PEA15,PELI3,PF4,PGAP2,PHIP,PIAS1,PIDD1,PIH1D1,PIK3CA,PIK3CG,PIK3R1,PIM1,PIM2,PIM3,PIN1,PINK1,PIP,PKHD1,PLAC8,PLK1,PLK2,PLK3,POR,POU3F3,POU3F4,POU4F1,PPARD,PPARGC1A,PPIF,PPT1,PRAMEF1,PRAMEF12,PRAMEF14,PRAMEF19,PRAMEF20,PRDX2,PRDX3,PRDX5,PRELID1,PRKAA1,PRKAA2,PRKCA,PRKCD,PRKCG,PRKCH,PRKCI,PRKCQ,PRKCZ,PRKDC,PRKN,PRLR,PROC,PROK2,PROKR1,PROP1,PSEN1,PSEN2,PSMD10,PSME3,PTEN,PTGFR,PTH,PTK2,PTK2B,PTPN1,PTTG1IP,RAF1,RAG1,RAMP2,RARA,RARB,RARG,RASA1,RB1CC1,RELA,RETREG1,RFFL,RGL2,RGN,RHBDD1,RIPK1,RIPK2,RNF144B,RNF34,RPS27A,RPS6,RPS6KA1,RPS6KA3,RRM2B,RRN3,RXFP2,SCG2,SCRT2,SCX,SEMA4D,SEMA5A,SERPINB13,SERPINB2,SERPINB9,SETX,SFN,SFRP1,SFRP2,SH3RF1,SHC1,SIAH2,SIRT1,SIRT4,SIRT5,SLC25A27,SLC25A5,SLC30A10,SLC35F6,SLC39A10,SLC40A1,SLC46A2,SLC9A1,SMO,SNAI1,SNAI2,SNCA,SNCB,SOCS2,SOCS3,SOD1,SOD2,SON,SOX10,SOX8,SOX9,SPHK1,SPHK2,SPRY2,SQSTM1,SRC,SRSF6,STAMBP,STAR,STIL,STRADB,STXBP1,SYCP2,SYNGAP1,SYVN1,TAF9,TAF9B,TAX1BP1,TBX1,TBX3,TCL1A,TDGF1,TEK,TERT,TEX11,TFAP2A,TFAP2B,TFAP2D,TGFBR1,THBS1,THOC6,TIMP1,TLE1,TMBIM1,TMBIM4,TMBIM6,TMEM14A,TMEM161A,TMIGD1,TNF,TNFAIP3,TNFAIP8,TNFRSF10A,TNFRSF10B,TNFRSF10C,TNFRSF10D,TNFRSF18,TNFRSF1B,TNFSF10,TNFSF14,TNFSF18,TNIP2,TOPORS,TP53,TP63,TP73,TPT1,TRADD,TRAF2,TRAF6,TRAP1,TRIAP1,TRIM32,TSC22D4,TWIST1,TWIST2,TXNDC5,TYRO3,UBC,UBE2V2,UCN,UCP2,UFL1,UNC5B,UNG,USP47,VEGFA,VHLL,VIL1,VNN1,VSTM2L,VTCN1,WFS1,WNK3,WNT1,WNT11,WNT4,WNT5A,WNT7A,WNT9A,XBP1,XIAP,XRCC2,YBX3,YME1L1,YWHAE,YWHAZ,ZC3H12A,ZC3HC1,ZFAND6,ZNF16,ZNF385A,ZNF830,ZPR1	TetrapodAncestor	280.971
GO.Biological.Process	GO:0043069	negative.regulation.of.programmed.cell.death	55	2.368205e-285	3.059010e-281	5.561837e-283	1.218505e+0	AAMDC,AARS,AATF,ABL1,ACAA2,ACKR3,ADA,ADAM8,ADAMTS20,ADAR,ADCYAP1,ADNP,ADORA1,ADORA2A,AGAP2,AGO4,AHI1,AIF1,AIPL1,AKR1B1,AKT2,ALB,ALKBH1,AMBRA1,AMIGO2,ANGPT1,ANGPT4,ANGPTL4,ANXA1,ANXA4,ANXA5,APBB2,API5,APIP,APOE,APOH,AQP1,AR,ARAF,ARF4,ARG2,ARHGDIA,ARHGEF2,ARL6IP1,ARNT2,ARRB1,ARRB2,ASCL1,ASIC2,ASNS,ATAD3A,ATF5,ATG5,ATOH1,AURKA,AURKB,AVP,AXL,BABAM2,BAD,BAG1,BAG4,BAG6,BARD1,BARHL1,BAX,BCL10,BCL11B,BCL2,BCL2A1,BCL2L1,BCL2L10,BCL2L12,BCL2L2,BCL2L2-PABPN1,BCL3,BCL6,BDKRB2,BDNF,BECN1,BFAR,BID,BIRC2,BIRC3,BIRC5,BIRC6,BMP4,BMP5,BMP7,BNIP1,BNIP3,BNIP3L,BRAF,BRCA1,BTC,BTG2,C8orf4,CAMK1D,CARD14,CARD16,CASP2,CASP3,CASP8,CAST,CAT,CAV1,CBL,CBX4,CCAR2,CCL19,CCL2,CCL21,CCL5,CCND2,CCR7,CD27,CD38,CD44,CD59,CD74,CDC73,CDK1,CDKN1A,CDKN1B,CDKN2D,CEBPB,CFDP1,CFL1,CFLAR,CHD8,CHL1,CHST11,CIAPIN1,CIB1,CIDEA,CITED1,CITED2,CLCF1,CLN3,CLU,CNTF,CNTFR,COL2A1,CORO1A,CPEB4,CREB3,CREB3L1,CRYAA,CRYAB,CSF1R,CSNK2A1,CTH,CTNNA1,CTNNB1,CTSH,CTTN,CX3CL1,CX3CR1,CYR61,DAB2,DAD1,DAPK1,DCPS,DDB1,DDIAS,DDRGK1,DDX3X,DFFA,DHCR24,DHRS2,DKK1,DLL1,DNAJA1,DNAJA3,DNAJB6,DOCK8,DPEP1,DRAXIN,DSTYK,DUSP1,DYRK3,EDN1,EDNRB,EEF2K,EFNA1,EGFR,EGR3,EIF2AK2,ELL3,EN1,EPCAM,EPO,ERBB4,ERC1,ERCC5,EYA1,EYA2,EYA3,EYA4,F2R,FABP1,FADD,FAIM2,FAM129B,FAS,FASLG,FCER1G,FCMR,FFAR4,FGF10,FGF20,FGF21,FGF4,FGFR2,FGG,FHL2,FIGNL1,FLNA,FLT3LG,FLT4,FMN2,FOXC1,FOXC2,FOXE3,FOXO1,FXN,FZD3,FZD9,GABRA5,GABRB2,GABRB3,GAS6,GATA3,GATA6,GCLM,GDF5,GDNF,GFRAL,GHSR,GLI2,GLI3,GLO1,GNRH1,GOLPH3,GPAM,GREM1,GRIK2,GRIN1,GRINA,GRK5,GSTP1,HAND2,HAX1,HCK,HCLS1,HDAC1,HDAC2,HDAC3,HERPUD1,HEY2,HGF,HIF1A,HIGD1A,HIGD2A,HIP1R,HIPK2,HMGA2,HMGB2,HMGCR,HMGN5,HMOX1,HNF1B,HNRNPK,HPN,HRAS,HSF1,HSH2D,HSP90AB1,HSP90B1,HSPA5,HSPA9,HSPB1,HSPB6,HSPH1,HTR2B,HTRA2,HTT,HYOU1,HYPK,ID1,IDO1,IER3,IFI6,IFIT3,IGBP1,IGF1,IGF1R,IHH,IKBKB,IL10,IL13,IL19,IL1A,IL1B,IL2,IL2RB,IL31RA,IL4,IL6,IL6ST,IL7,ING2,INS,INSL6,IRAK1,IRF7,IRS2,ISL1,ITCH,ITGA5,ITGAV,ITGB1,ITPKB,ITSN1,IVNS1ABP,JAK2,JAK3,JUN,KANK2,KDM1A,KDM2B,KIFAP3,KITLG,KLF4,KLHL20,KRAS,KRIT1,LACRT,LAMP3,LEF1,LEP,LGALS3,LGMN,LHX4,LIG4,LIMS2,LMNA,LRP1,LRP6,LRRK2,LTK,MAD2L1,MAEA,MAEL,MAG,MALT1,MAP2K4,MAP3K12,MAP4K4,MAPK8,MAPK8IP1,MDK,MDM2,MDM4,MECOM,MECP2,MEF2C,MEIS3,MERTK,MET,MICAL1,MIEN1,MIF,MMP9,MNT,MPO,MPV17L,MRE11,MSH2,MSX1,MSX2,MTDH,MTOR,MUC1,MYC,MYDGF,MYO18A,MYOCD,NAA15,NAA16,NAA35,NAA38,NAIP,NANOS3,NAT8,NCKAP1L,NDNF,NDUFS3,NEFL,NES,NEUROD1,NFKB1,NGF,NGFR,NKX2-5,NKX2-6,NKX3-2,NLE1,NLRC4,NME2,NME5,NOC2L,NOG,NOL3,NOS3,NOTCH1,NOTCH2,NPM1,NPY5R,NQO1,NR1H4,NR4A2,NR4A3,NRP1,NTF3,NTF4,NTRK1,NTRK2,NTSR1,NUAK2,NUGGC,NUP62,OGG1,OPA1,OSR1,OXR1,PAFAH2,PAK2,PAK5,PALB2,PARK7,PAX2,PAX4,PAX7,PAX8,PCGF2,PCID2,PDCD1,PDCD10,PDE3A,PDGFRB,PDPK1,PDPN,PEA15,PELI3,PF4,PGAP2,PHIP,PIAS1,PIDD1,PIH1D1,PIK3CA,PIK3CG,PIK3R1,PIM1,PIM2,PIM3,PIN1,PINK1,PIP,PKHD1,PLAC8,PLCG2,PLK1,PLK2,PLK3,POR,POU3F3,POU3F4,POU4F1,PPARD,PPARGC1A,PPIF,PPT1,PRAMEF1,PRAMEF12,PRAMEF14,PRAMEF19,PRAMEF20,PRDX2,PRDX3,PRDX5,PRELID1,PRKAA1,PRKAA2,PRKCA,PRKCD,PRKCG,PRKCH,PRKCI,PRKCQ,PRKCZ,PRKDC,PRKN,PRLR,PROC,PROK2,PROKR1,PROP1,PSEN1,PSEN2,PSMC5,PSMD10,PSME3,PTEN,PTGFR,PTH,PTK2,PTK2B,PTPN1,PTTG1IP,RAF1,RAG1,RAMP2,RARA,RARB,RARG,RASA1,RB1CC1,RBCK1,RELA,RETREG1,RFFL,RGL2,RGN,RHBDD1,RIPK1,RIPK2,RNF144B,RNF34,RPS27A,RPS6,RPS6KA1,RPS6KA3,RRM2B,RRN3,RXFP2,SCG2,SCRT2,SCX,SEMA4D,SEMA5A,SERPINB13,SERPINB2,SERPINB9,SETX,SFN,SFRP1,SFRP2,SH3RF1,SHC1,SIAH2,SIRT1,SIRT4,SIRT5,SLC25A27,SLC25A5,SLC30A10,SLC35F6,SLC39A10,SLC40A1,SLC46A2,SLC9A1,SMO,SNAI1,SNAI2,SNCA,SNCB,SOCS2,SOCS3,SOD1,SOD2,SON,SOX10,SOX8,SOX9,SPHK1,SPHK2,SPRY2,SQSTM1,SRC,SRSF6,STAMBP,STAR,STIL,STRADB,STXBP1,SYCP2,SYNGAP1,SYVN1,TAF9,TAF9B,TAX1BP1,TBX1,TBX3,TCL1A,TDGF1,TEK,TERT,TEX11,TFAP2A,TFAP2B,TFAP2D,TGFBR1,THBS1,THOC6,TIGAR,TIMP1,TLE1,TM7SF3,TMBIM1,TMBIM4,TMBIM6,TMEM14A,TMEM161A,TMIGD1,TNF,TNFAIP3,TNFAIP8,TNFRSF10A,TNFRSF10B,TNFRSF10C,TNFRSF10D,TNFRSF18,TNFRSF1B,TNFSF10,TNFSF14,TNFSF18,TNIP2,TOPORS,TP53,TP63,TP73,TPT1,TRADD,TRAF2,TRAF6,TRAP1,TRIAP1,TRIM32,TSC22D4,TWIST1,TWIST2,TXNDC5,TYRO3,UBC,UBE2V2,UCN,UCP2,UFL1,UNC5B,UNG,USP47,VEGFA,VHLL,VIL1,VNN1,VSTM2L,VTCN1,WFS1,WNK3,WNT1,WNT11,WNT4,WNT5A,WNT7A,WNT9A,XBP1,XIAP,XRCC2,YBX3,YME1L1,YWHAE,YWHAZ,ZC3H12A,ZC3HC1,ZFAND6,ZNF16,ZNF385A,ZNF830,ZPR1	TetrapodAncestor	280.514
GO.Biological.Process	GO:0072359	circulatory.system.development	56	3.055421e-283	3.946687e-279	7.047656e-281	1.190562e+0	AAMP,ABL1,ACKR3,ACTA2,ACVR2B,ACVRL1,ADAM15,ADAM19,ADAM8,ADAMTS1,ADAMTS9,ADAP2,ADGRA2,ADGRG1,ADGRG6,ADIPOR2,ADM2,ADRA1A,AGGF1,AGT,AGTR2,AHI1,AHR,AKAP13,AMOT,ANGPT1,ANGPT2,ANGPT4,ANGPTL4,ANK2,ANKRD1,ANKRD17,ANPEP,ANTXR1,AP1B1,AP2B1,APELA,APLNR,APOB,APOD,APOE,APOLD1,AQP1,ARHGAP22,ARHGAP24,ARID1A,ARID2,ARL13B,ASXL1,ATG5,ATM,ATPIF1,AXIN2,B4GALT1,B9D1,BAK1,BAX,BBS4,BBS7,BCAS3,BCOR,BICC1,BMP10,BMP2,BMP4,BMP5,BMP7,BMPER,BMPR1A,BMPR2,BVES,C1GALT1,C2CD3,C3orf58,C5orf42,CACNA1C,CACYBP,CALCRL,CALR,CASP3,CAV1,CAV3,CBY1,CCBE1,CCDC103,CCDC40,CCL2,CCM2,CCM2L,CCNB1,CD34,CDC42,CDH13,CDH2,CDH5,CDK1,CER1,CHD7,CIB1,CITED1,CITED2,CLDN5,COL11A1,COL15A1,COL18A1,COL1A1,COL1A2,COL2A1,COL3A1,COL5A1,COL8A1,COL8A2,COX17,CRB2,CRELD1,CRIP1,CRKL,CSPG4,CSRP3,CTGF,CTNNB1,CUL7,CX3CL1,CXADR,CXCL8,CXCR3,CYP1B1,CYR61,DAB2IP,DAND5,DAW1,DCHS1,DCTN5,DHCR7,DHRS3,DLC1,DLL1,DLL4,DLX3,DNAAF1,DNAH5,DNM2,DRC1,DSG2,DSP,DVL1,DYNC2H1,E2F7,E2F8,ECE2,ECSCR,EDN1,EFNA1,EFNB2,EGF,EGFL7,EGLN1,EGR1,EGR3,EIF2AK3,ELK3,ENG,ENPEP,ENSG00000259753,EOMES,EP300,EPAS1,EPC1,EPGN,EPHA1,EPHA2,EPHB1,EPHB2,EPHB3,EPHB4,EPOR,ERAP1,ERBB2,ERBB4,EREG,ERG,ERRFI1,ESM1,ETS1,EYA1,FAT4,FBXW7,FBXW8,FGF1,FGF10,FGF12,FGF18,FGF19,FGF2,FGF6,FGF9,FGFR1,FGFR2,FGFRL1,FHL2,FHOD3,FKBP1A,FLRT2,FLRT3,FLT1,FLT4,FLVCR1,FMNL3,FN1,FOSL1,FOXC1,FOXC2,FOXF1,FOXH1,FOXJ1,FOXL1,FOXN1,FOXN4,FOXO1,FOXS1,FREM2,FRS2,FZD1,FZD2,FZD4,FZD5,FZD8,GAA,GAB1,GALNT11,GATA3,GATA4,GATA6,GBX2,GDF2,GGNBP2,GJA1,GJA4,GJC1,GLI2,GLI3,GNA11,GNA13,GNAQ,GPC3,GPLD1,GPR4,GREM1,GRHL2,GRK2,GSK3A,GYS1,HAND1,HAND2,HAS2,HDAC7,HDAC9,HEG1,HES1,HEXIM1,HEY1,HEY2,HEYL,HHEX,HIF1A,HIF3A,HMOX1,HNRNPU,HOXA1,HPGD,HPSE,HRG,HS6ST1,HSPB11,HSPG2,HTR2B,ID1,ID3,IFT140,IFT172,IFT20,IFT52,IFT57,IFT74,IHH,IL18,IMMP2L,ISL1,ITGA3,ITGA5,ITGAV,ITGB1,ITGB8,JAG1,JAM3,JMJD6,JUN,JUNB,KCNAB1,KCNJ8,KCNK2,KCNQ1,KDM6A,KDM6B,KLF5,KRIT1,LAMA5,LBX1,LEF1,LEFTY1,LEMD2,LEMD3,LEP,LEPR,LGALS8,LIF,LMNA,LMO4,LOX,LOXL1,LOXL2,LRP1,LRP5,LRP6,LRRC10,LUZP1,LYL1,MAML1,MAP2K4,MAP3K3,MAPK1,MAPK14,MAPK3,MB,MBD1,MBD2,MBD3,MCAM,MDM2,MEF2A,MEF2C,MEF2D,MEGF8,MEIS1,MEOX2,MESP1,MESP2,MFGE8,MIB1,MIXL1,MKKS,MMP14,MMP19,MMRN2,MSX1,MSX2,MTERF4,MTHFD1,MTOR,MYBPC3,MYDGF,MYH6,MYH7,MYH9,MYL3,MYLK,MYLK2,MYLK3,MYO1E,MYOCD,MYPN,NAA15,NCL,NCOA6,NDNF,NDP,NDRG4,NDST1,NEBL,NEK8,NF1,NFATC4,NIPBL,NKX2-5,NKX2-6,NKX3-1,NOG,NOS3,NOTCH1,NOTCH2,NOTCH3,NOTCH4,NOTO,NOV,NOX4,NOX5,NPHP3,NPRL3,NPY1R,NPY2R,NPY5R,NR4A1,NRG1,NRP1,NRP2,NSD2,NSDHL,NTRK2,NTRK3,NUS1,NXN,OLFM1,OSR1,OTULIN,OVOL2,OXCT1,OXT,OXTR,PAM,PAX8,PAXIP1,PCNA,PCSK5,PDCD10,PDCD6,PDCL3,PDGFA,PDGFB,PDGFRB,PDLIM3,PDLIM5,PDPN,PECAM1,PIK3CA,PIK3CG,PIK3R6,PITX2,PKD1,PKD2,PKNOX1,PKP2,PLCD3,PLCE1,PLG,PLN,PLXDC1,PLXND1,POGLUT1,POU4F1,PPARA,PPARD,PPARG,PPP1R13L,PPP3CB,PRCP,PRDM1,PRICKLE1,PRKAR1A,PRKCA,PRKD1,PRKD2,PRKDC,PRKX,PROK1,PROK2,PROP1,PROX1,PRRX1,PSEN1,PSKH1,PTCD2,PTCH1,PTEN,PTK2,PTK2B,PTK7,PTN,PTPN11,PTPN14,PTPRB,QKI,RAF1,RAMP1,RAMP2,RAPGEF1,RAPGEF2,RAPGEF3,RARA,RARB,RASA1,RASIP1,RB1CC1,RBP4,RBPJ,RECK,REST,RHOJ,RIC8A,RIPPLY3,RNF213,ROBO1,ROBO4,ROM1,RSPO3,RTN4,RXRA,RYR1,RYR2,S100A7,S1PR1,SAT1,SCG2,SCN5A,SCUBE1,SCX,SEC24B,SEMA3C,SEMA3E,SEMA4A,SEMA5A,SETD2,SETDB2,SFRP2,SGCB,SGCD,SGCG,SGCZ,SGPL1,SH2D2A,SHB,SHC1,SHOX2,SIK1,SIRT1,SIRT6,SLC12A6,SLC8A1,SLC9A1,SLIT2,SLITRK5,SMAD2,SMAD4,SMAD7,SMO,SMYD1,SMYD2,SNAI1,SNAI2,SNX17,SOCS3,SORBS2,SOS1,SOX11,SOX17,SOX18,SOX4,SOX9,SPHK1,SPHK2,SPI1,SPINT1,SPRED1,SPRY1,SRF,SRI,SRPK2,SRPX2,STAB2,STIL,STK4,STRA6,SUFU,SYK,T,TAB1,TAB2,TAL1,TAZ,TBC1D32,TBX1,TBX2,TBX20,TBX3,TBX5,TCF21,TCF25,TDGF1,TEAD2,TEK,TENM4,TFAP2B,TFDP2,TGFB1,TGFB2,TGFBI,TGFBR1,TGFBR2,TH,THBS1,THSD7A,THY1,TIE1,TIPARP,TMED2,TMEM100,TMEM2,TMEM204,TMEM231,TMEM65,TMPRSS6,TNFRSF12A,TNFSF12,TNNC1,TNNI3,TNNT2,TRAF3IP1,TRIP11,TSC2,TSPAN12,TTN,TWIST1,TYMP,UBP1,UNC5B,VANGL2,VASH1,VASH2,VAV2,VAV3,VEGFA,VEGFB,VEGFC,VEGFD,VEZF1,VHLL,WARS,WARS2,WASF2,WNT11,WNT16,WNT3A,WNT5A,WNT7A,WNT7B,WNT8A,XBP1,XIRP1,ZBTB14,ZC3H12A,ZDHHC16,ZFAND5,ZFP36L1,ZFPM1,ZFPM2,ZIC3,ZMIZ1	TetrapodAncestor	278.404
GO.Biological.Process	GO:0051093	negative.regulation.of.developmental.process	57	2.745342e-282	3.546158e-278	6.221330e-280	1.190208e+0	ABCA1,ABCA5,ABCC8,ABCG1,ABL1,ABR,ACTN4,ACVRL1,ADAMTS12,ADAMTS7,ADAMTS9,ADCYAP1,ADGRB1,ADGRB2,ADGRB3,ADGRG1,ADIPOQ,ADIPOR1,ADRB2,ADRB3,AGT,AHSG,AMH,AMOT,ANGPT2,ANGPT4,ANKRD17,ANKRD2,ANKRD26,ANXA1,AP1AR,APOE,APOH,APP,AREG,ARF6,ARHGAP4,ARHGDIA,ARHGDIB,ARHGEF2,ARNTL,ARPIN,ASAP1,ASCL1,ASCL2,ASPM,ASPN,ASXL1,AXIN2,BBS12,BCL11A,BCL2,BCL2L12,BCL6,BCOR,BCR,BDNF,BHLHA15,BHLHE41,BMP2,BMP4,BMP5,BMP7,BMPR1A,BMPR2,BNIP3,BRINP1,C16orf45,C1QC,C1QL4,CALR,CARM1,CARTPT,CAV1,CAV3,CBFA2T2,CCDC85B,CCL17,CCL2,CCL3,CCND1,CCR1,CCR2,CD74,CD86,CDC73,CDH3,CDK13,CDK5,CDK5R1,CDK5RAP2,CDK6,CDKN1B,CEND1,CER1,CERS2,CETP,CFLAR,CHAD,CHRD,CIB1,CITED1,CLASP1,CLASP2,CLDN18,CMTM5,CNMD,CNTF,CNTN2,CNTN4,COL3A1,COL4A3,COL5A1,COL5A2,CPB2,CRMP1,CTDP1,CTDSP1,CTLA4,CTNNA1,CTNNB1,CTSZ,CUL4A,CX3CR1,CXCL10,CXCL14,DAB1,DAB2IP,DACT3,DAND5,DCC,DCN,DGUOK,DISP3,DIXDC1,DKK1,DKK4,DLL1,DLL3,DLL4,DMTN,DNM1L,DPYSL3,DRAXIN,DRD3,DTX1,DUSP10,DYNLT1,E2F1,ECSCR,EDNRB,EFEMP1,EFNA1,EFNA3,EFNA5,EFNB2,EFNB3,EGFR,EID2B,EIF2AK3,EIF2AK4,EIF4E,EIF4ENIF1,ELF5,ENPP1,EPHA2,EPHA4,EPHA7,EPHB1,EPHB2,ERBB2,ERBB4,EREG,ESRRB,EZH2,F2,FAM129B,FAM57B,FAM60A,FASLG,FBLN1,FBXO7,FBXW7,FERMT1,FGF10,FGF13,FGF23,FGF3,FGFR3,FKBP4,FLCN,FOXA1,FOXA2,FOXC1,FOXC2,FOXE3,FOXG1,FOXJ1,FOXM1,FOXO1,FOXO4,FOXP3,FRS2,FSTL3,FSTL4,FUOM,FUZ,FXN,FZD3,FZD7,FZR1,G6PD,GABPA,GAK,GAL,GAS6,GATA2,GATA3,GDF10,GDF11,GDF2,GDF3,GDF5,GDI1,GFAP,GJA1,GLI2,GLI3,GNRH1,GPER1,GPR161,GPR171,GPR37L1,GPR4,GPR55,GPR68,GREM1,GRHL2,GSK3A,GTF2I,HAND2,HDAC2,HDAC4,HDAC5,HDAC7,HDAC8,HES1,HES5,HEY2,HHEX,HIF1A,HIST1H4J,HIST1H4K,HIST1H4L,HIST2H4B,HIST4H4,HLX,HMG20A,HMGA2,HMGB1,HMGB3,HNF1B,HNRNPU,HOOK3,HPN,HRG,HSPA9,HSPG2,IAPP,ID1,ID2,ID3,ID4,IDH2,IFNA2,IFNB1,IFNG,IFNL1,IFRD1,IGF1,IGFBP5,IHH,IL13,IL17F,IL18,IL2,IL4,IL6,INHA,INHBA,INPP5D,INPP5J,IRF1,ISL1,ITGAV,ITGB1,ITM2C,ITPKB,JAG1,JAK3,JARID2,KANK1,KCNK2,KIAA0319,KLF13,KLF4,KRAS,KRIT1,LBH,LBX1,LDLRAD4,LEF1,LEO1,LEP,LFNG,LGALS1,LGMN,LILRB4,LIMD1,LIMS2,LIN28A,LINGO1,LMX1A,LOXL3,LPAR1,LRIG2,LRP1,LRP4,LRP5,LRRC17,LSM1,LUC7L,LYN,MAD2L2,MAFB,MAG,MAP4K4,MAPK1,MAPK11,MAPT,MARCH5,MBD1,MBNL3,MCF2,MDM2,MECP2,MED28,MEIS1,MEIS2,MELTF,MEN1,MEOX2,MEPE,MESP1,MIB1,MIF,MIXL1,MMP11,MMRN2,MSTN,MSX1,MSX2,MTMR2,MUL1,MYC,MYCN,MYOCD,NBR1,NDFIP1,NEPRO,NF1,NFATC4,NFIB,NFKBID,NGEF,NGFR,NKX2-5,NKX3-1,NKX3-2,NKX6-1,NLGN1,NLGN3,NME1,NME2,NMRK2,NOCT,NOG,NOTCH1,NOTCH3,NOTCH4,NOV,NPHP3,NPPC,NPR1,NPR2,NR0B1,NR1H2,NR1H3,NRG1,NRG3,NRP1,NTRK3,OLIG2,OMA1,OMG,OSR1,OSTN,OVOL2,PAEP,PAF1,PAFAH1B1,PAK1,PAX2,PAX8,PBLD,PBX1,PCM1,PDCD1,PDCD10,PDGFB,PF4,PGK1,PGLYRP1,PGLYRP2,PGLYRP3,PHF14,PHLDB2,PHOX2B,PIK3R1,PINK1,PKP2,PLAC8,PLK2,PLXNA3,PML,PMP22,PPARA,PPARD,PPARG,PPARGC1A,PPP3CA,PRAMEF1,PRAMEF12,PRAMEF14,PRAMEF19,PRAMEF20,PRICKLE1,PRKACA,PRKDC,PRKN,PRMT1,PRMT5,PRPF19,PSEN1,PTCH1,PTEN,PTH,PTHLH,PTK2,PTK2B,PTN,PTPRG,PTPRM,PTPRO,PTPRS,RAB29,RAI1,RANBP3L,RAP1GAP2,RAPGEF2,RAPGEF3,RARA,RARB,RARG,RBP4,RBPJ,RBPMS2,RC3H1,RCC2,REG3A,REG3G,REST,RFLNB,RGCC,RGMA,RGN,RIOX1,RIT2,RNF10,RNF6,ROBO1,ROBO2,ROCK2,RORB,RPS6KA6,RSPO2,RTN4,RTN4R,RTN4RL2,RUFY3,RUNX1T1,S100B,S1PR3,SARS,SDHAF2,SEMA3A,SEMA3E,SEMA3G,SEMA4A,SEMA4D,SEMA5A,SFMBT1,SFRP1,SFRP2,SFRP5,SHB,SIRT1,SIRT2,SIX2,SKI,SKIL,SKOR2,SLC30A10,SLC6A4,SLIT1,SLIT2,SMAD4,SMAD7,SMO,SNAI1,SNAI2,SNAPIN,SOCS2,SOCS5,SORL1,SOST,SOSTDC1,SOX10,SOX11,SOX15,SOX17,SOX2,SOX3,SOX8,SOX9,SPINK5,SPOCK1,SPP1,SPRED1,SRGAP2,SRGAP2C,SRSF6,STAP1,STARD13,STAT1,STC2,STK4,STMN2,STRAP,STX1B,SUFU,SYNGAP1,SYNJ2BP,SYT4,TACSTD2,TBX1,TBX18,TBX2,TBX3,TBX5,TBX6,TEK,TERF2,TERT,TGFB1,TGFB1I1,TGFB2,TGFBR1,TGFBR2,THBS1,THBS2,THBS4,THOC1,THOC2,THY1,TIE1,TIMP1,TJP2,TLL2,TLR2,TLR3,TLR4,TLX2,TLX3,TMEM131L,TMEM176A,TMEM176B,TMEM178A,TMEM64,TNF,TNFRSF11B,TNFRSF21,TNFRSF8,TNFSF18,TNMD,TNN,TNR,TP53INP1,TP63,TP73,TRAF3IP1,TRAK2,TRIB1,TRIB2,TRIB3,TRIM11,TRIM6,TRIM62,TRIM72,TRIO,TRPC5,TRPC6,TRPM4,TRPV1,TSPO,TTPA,TULP3,TUNAR,TWIST1,TWIST2,UBASH3B,UBE3A,UCMA,ULK2,USH2A,VASH1,VAT1,VHLL,VIM,WDR61,WDR77,WEE2,WNT1,WNT10B,WNT11,WNT3,WNT3A,WNT4,WNT5A,WNT7A,WNT9A,WNT9B,WWC1,WWC2,WWC3,WWTR1,XBP1,XDH,YBX1,YBX3,YWHAH,ZBTB16,ZC3H8,ZEB1,ZFP36,ZFP36L1,ZFP36L2,ZFPM1,ZFPM2,ZHX2,ZNF365,ZNF675,ZNF706	TetrapodAncestor	277.45
GO.Biological.Process	GO:0043068	positive.regulation.of.programmed.cell.death	58	8.242471e-282	1.064680e-277	1.835655e-279	1.261958e+0	ABL1,ABR,ACER2,ADAM8,ADCY10,ADIPOQ,ADORA2A,AES,AGT,AGTR2,AIFM1,AIFM2,AKAP13,ALDH1A3,ANKRD1,ANO6,ANXA1,APAF1,APBB2,APC,APH1A,APH1B,ARHGEF1,ARHGEF11,ARHGEF12,ARHGEF16,ARHGEF17,ARHGEF19,ARHGEF2,ARHGEF26,ARHGEF3,ARHGEF4,ARHGEF7,ARHGEF9,ARL6IP5,ARRB1,ASCL1,ATF3,ATF4,ATF6,ATM,ATPIF1,B4GALT1,BAD,BAK1,BARD1,BAX,BCAP31,BCL10,BCL2,BCL2A1,BCL2L1,BCL2L10,BCL2L11,BCL2L13,BCL6,BCLAF1,BID,BIK,BIN1,BLID,BMP2,BMP4,BMP7,BMPR1B,BNIP3,BNIP3L,BTG1,C1QBP,C3orf38,CAMK1D,CAMK2A,CAMK2D,CAPN10,CASP1,CASP2,CASP3,CASP8,CASP9,CAV1,CCAR2,CCK,CCL3,CCL5,CD274,CD40,CDC34,CDC42,CDK19,CDK4,CDK5,CDK5R1,CDKN1A,CDKN2A,CHEK2,CIDEB,CLIP3,CNR1,COL18A1,COL4A3,CRADD,CREB1,CRYBA1,CTGF,CTLA4,CTNNA1,CTNNB1,CTNNBL1,CTSC,CTSH,CTSZ,CYCS,CYP1B1,CYR61,DAB2IP,DAP,DAPK1,DAPK3,DCUN1D3,DDX3X,DEDD2,DFFA,DFNA5,DHODH,DKKL1,DLC1,DNAJA1,DNM1L,DNM2,DUSP1,DUSP6,DYNLL1,DYNLL2,E2F1,ECSCR,ECT2,EGLN3,EIF2AK3,EIF2B5,ENDOG,EPHA7,ERBB4,ERCC3,F2R,F3,FADD,FAF1,FAM162A,FAS,FASLG,FBXO18,FBXW7,FGD1,FGD2,FGD3,FGD4,FIS1,FLCN,FOSL1,FOXA1,FOXO1,FZD9,G0S2,GADD45A,GADD45B,GADD45G,GAL,GAPDH,GNA13,GPER1,GPLD1,GRAMD4,GRIK2,GRIK5,GRIN1,GRIN2A,GSK3A,GSN,GZMA,HDAC4,HIP1,HIP1R,HMGA2,HMGB1,HMGCR,HMOX1,HPGD,HRG,HRK,HSF1,HTRA2,HTT,IAPP,ID3,IDO1,IFI27,IFIT2,IFNB1,IFNG,IFT57,IGF2R,IL10,IL12A,IL12B,IL19,IL20RA,IL6,INCA1,ING3,ING5,INHBA,INHBB,INPP5D,ITGA1,ITGB1,ITM2C,ITSN1,JAK2,JMY,JUN,KALRN,KCNMA1,KLF11,KNG1,LATS1,LATS2,LCK,LDHA,LEP,LGALS13,LGALS14,LGALS16,LGALS9,LPAR1,LRRK2,LTBR,LTK,LYN,MAP2K4,MAP2K6,MAP3K10,MAP3K11,MAP3K5,MAP3K9,MAPK8,MAPK9,MAPT,MARK4,MCF2,MCF2L,MEF2C,MELK,MFF,MLLT11,MMP9,MSX1,MSX2,MTCH1,MTCH2,MUL1,MYB,MYBBP1A,MYBL2,MYC,NCK1,NCK2,NCOA1,NCSTN,NET1,NEURL1,NEUROD1,NF1,NFATC4,NFKBID,NGEF,NGF,NGFR,NKX3-1,NLRC4,NLRP1,NLRP2,NMT1,NOD1,NOTCH1,NOX4,NQO1,NQO2,NR4A3,NSMAF,NTRK1,NTRK3,NTSR1,NUPR1,OBSCN,OSGIN1,OSM,P2RX7,PAK2,PAK3,PANO1,PARK7,PAWR,PDCD1,PDCD2,PDCD5,PDCD6,PDGFRB,PDIA3,PEA15,PIAS4,PIDD1,PIK3CD,PIN1,PINK1,PLA2G6,PLEKHF1,PLEKHG2,PLEKHG5,PMAIP1,PML,PNMA1,PNMA2,PNMA5,POU4F1,PPARG,PPARGC1A,PPIF,PPM1F,PPP1R13B,PPP2R1B,PPP3CC,PPP3R1,PRELID1,PREX1,PRKCD,PRKCI,PRKDC,PRKRA,PSEN1,PSEN2,PSENEN,PTEN,PTGIS,PTN,PTPA,PXT1,PYCARD,RAC1,RAD9A,RAPGEF2,RAPSN,RARB,RARG,RASGRF2,RASSF2,RBCK1,RBM5,REST,RET,RGCC,RIPK1,RIPK2,RIPK3,RNPS1,ROBO1,RPL11,RPS27A,RPS27L,RPS3,RPS6,RPS6KA2,RPS7,RRP1B,RYBP,S100A8,S100A9,S100B,SAP18,SCIN,SCRIB,SEPT4,SERINC3,SFN,SFPQ,SFRP1,SFRP2,SFRP4,SIAH1,SIK1,SIRT1,SIRT2,SKIL,SLC9A1,SLC9A3R1,SLIT2,SMPD1,SNCA,SOD1,SOS1,SOX4,SOX7,SPOP,SQSTM1,SRC,SRPK2,SRPX,ST18,STK17A,STK17B,STK4,STPG1,SUDS3,SYCE3,TFAP2A,TFAP2B,TFDP2,TGFB1,TGFB2,TGFBR1,TGM2,THBS1,TIA1,TIAM1,TIAM2,TIGAR,TIMP3,TLR3,TNF,TNFAIP8,TNFRSF10A,TNFRSF10B,TNFRSF12A,TNFRSF8,TNFSF10,TNFSF12,TNFSF15,TOP2A,TP53,TP53BP2,TP53INP1,TP63,TP73,TPD52L1,TRADD,TRAF2,TRAF6,TRAF7,TRIM35,TRIM39,TRIO,TRPV1,TSPO,TXNIP,UBC,UBE2M,UNC13B,UNC5C,USP17L30,VAV1,VAV2,VAV3,VCP,VDR,WDR35,WNT10B,WNT11,WNT3A,WNT5A,WWOX,XDH,YWHAB,YWHAE,YWHAG,YWHAH,YWHAZ,ZBTB16,ZC3H12A,ZC3H8,ZMAT3,ZNF205,ZNF346,ZNF622,ZSWIM2	TetrapodAncestor	276.973
GO.Biological.Process	GO:0071900	regulation.of.protein.serine/threonine.kinase.activity	59	7.296431e-275	9.424800e-271	1.597424e-272	1.278806e+0	ABL1,ACSL1,ADAM8,ADAM9,ADIPOQ,ADORA1,ADORA2B,ADRA2A,ADRA2B,ADRB2,AGER,AIDA,AJUBA,AKAP13,ALK,ALS2,APC,APOE,ARAF,ARRB1,ATP2B4,AVPI1,BMP2,BMP4,BMP7,BRAF,C1QTNF2,C5,C8orf4,CAB39,CALM1,CALM2,CALM3,CAMK1,CARD10,CARD14,CARTPT,CASP3,CAV1,CAV3,CBLC,CCL19,CCNB1,CCNB3,CCND1,CCND2,CCND3,CCNE2,CCNG1,CCNH,CCNK,CCNL1,CCNL2,CCNT2,CCNYL1,CD24,CD300A,CD40,CD74,CD81,CDC25A,CDC25C,CDC6,CDK1,CDK5R1,CDK5R2,CDK5RAP1,CDK7,CDKN1A,CDKN1B,CDKN1C,CDKN2A,CDKN2B,CDKN2C,CDKN2D,CDKN3,CEBPA,CEMIP,CHI3L1,CHORDC1,CIB1,CKS1B,CKS2,CNPPD1,COPS8,CRK,CRKL,CSF1R,CSK,CSPG4,CXCR4,DAB2IP,DAXX,DBNL,DDX3X,DIRAS3,DKK1,DNAJA1,DRD4,DTNBP1,DUSP1,DUSP10,DUSP16,DUSP18,DUSP19,DUSP2,DUSP21,DUSP22,DUSP3,DUSP6,DUSP7,DUSP8,DUSP9,DVL3,EDN1,EDN3,EGF,EGFR,EIF2AK2,EPGN,EPHA4,EPHB2,ERBB2,ERCC6,ERN1,ERN2,ERP29,ETAA1,EZH2,F2R,FAM20A,FAM212A,FAM212B,FAM58A,FBXO7,FGD2,FGF1,FGF10,FGF18,FGF2,FGFR1,FLT1,FRS2,FZD10,FZD4,FZD5,FZD8,GADD45A,GADD45B,GADD45G,GBA,GH1,GHR,GNG3,GPS1,GRM4,GSTP1,GTF2H1,H2AFY,HACD3,HEXIM1,HEXIM2,HGF,HGS,HHEX,HMGCR,HRAS,HSP90AB1,HSPA2,HSPB1,HTR2A,HTR2B,IFNG,IGF1,IGF1R,IGF2,IKBKG,IL1B,INAVA,INCA1,INPP5K,IQGAP1,IQGAP3,IRAK1,IRAK3,IRGM,ITGA1,JAK2,KARS,KAT2B,KITLG,KRAS,LAMTOR2,LAMTOR3,LATS1,LATS2,LAX1,LPAR1,LPAR3,LRP5,LRP6,LRRK2,LYN,MADD,MALT1,MAP2K2,MAP2K3,MAP2K4,MAP2K6,MAP2K7,MAP3K1,MAP3K10,MAP3K11,MAP3K12,MAP3K13,MAP3K14,MAP3K15,MAP3K2,MAP3K21,MAP3K3,MAP3K4,MAP3K5,MAP3K6,MAP3K7,MAP3K7CL,MAP3K8,MAP3K9,MAP4K1,MAP4K3,MAP4K4,MAPK1,MAPK10,MAPK11,MAPK14,MAPK3,MAPK8IP1,MAPK8IP3,MAPKAPK2,MAPKAPK3,MAPKAPK5,MAPRE3,MAS1,MBIP,MEN1,MIF,MINK1,MLST8,MOS,MST1,MST1R,MTCP1,MUC20,MUL1,MYOCD,NEK10,NF1,NGF,NOD1,NOX4,NPFFR2,NRG1,NRK,NTF3,NTRK1,NTRK3,NUP62,P2RX7,PAK1,PAK3,PARP16,PDCD10,PDE5A,PDE6H,PDGFA,PDGFB,PDGFC,PDGFD,PDGFRB,PEA15,PIH1D1,PIK3CG,PIK3R5,PIK3R6,PKD1,PKD2,PKIA,PKIB,PKIG,PKMYT1,PKN1,PLA2G1B,PLCE1,PLCG1,PLK1,PPEF2,PRKAA1,PRKAG2,PRKAR1A,PRKAR1B,PRKAR2B,PRKCD,PROK1,PROK2,PROX1,PSEN1,PSMD10,PTEN,PTK2B,PTPN1,PTPN11,PTPN22,PTPRJ,PYCARD,RAF1,RALB,RAP1A,RAPGEF1,RAPGEF2,RASGRP1,RGCC,RGS14,RGS2,RGS3,RGS4,RIPK1,RIPK2,ROBO1,ROR2,RPS27A,RPS3,RPTOR,S100A12,SAA1,SASH1,SERPINB3,SESN2,SFN,SFRP1,SFRP2,SHC1,SHC2,SIRT1,SLC27A1,SMPD1,SNCA,SOD1,SORL1,SPAG9,SPDYA,SPRED1,SPRED2,SPRY1,SPRY2,SRC,STK24,STK26,STK38,STK4,STRADA,SYK,TAB1,TAB2,TAB3,TAOK1,TAOK2,TCL1A,TCL1B,TDGF1,TELO2,TENM1,TGFB1,TGFBR1,THBS1,THY1,TIAM1,TIRAP,TLR3,TLR4,TLR6,TLR9,TMEM189-UBE2V1,TNF,TNFAIP3,TNFRSF10A,TNFRSF10B,TNFRSF11A,TNFSF11,TNFSF15,TNIK,TP73,TPD52L1,TRAF2,TRAF4,TRAF6,TRAF7,TRIB1,TRIB2,TRIB3,TSG101,UBC,UBE2N,UCHL1,UVRAG,VANGL2,VEGFA,WEE2,WNK1,WNT5A,WNT7B,YWHAG,ZFP91,ZNF675	TetrapodAncestor	270.026
GO.Biological.Process	GO:0010563	negative.regulation.of.phosphorus.metabolic.process	60	1.265660e-273	1.634853e-269	2.724755e-271	1.244420e+0	ABL1,ADAR,ADARB1,ADIPOQ,ADORA2A,ADRA2A,AHSG,AIDA,AJUBA,AKAP6,AKT1S1,AMBP,ANGPT1,APC,APLP1,APOC1,APOE,ARFGEF3,ARRB1,ARRB2,ASH1L,ASPN,ATF3,ATG14,BAG4,BAK1,BAX,BDKRB1,BDKRB2,BGN,BMP4,BMP7,C14orf166,C1QL4,C3orf33,C9orf72,CACTIN,CALM1,CALM2,CALM3,CAMK2N1,CAMK2N2,CAMSAP3,CASP3,CAV1,CAV3,CBL,CBLB,CBLC,CCDC8,CCNB1,CCR2,CD109,CD2BP2,CD300A,CDA,CDK5RAP1,CDKN1A,CDKN1B,CDKN1C,CDKN2A,CDKN2B,CDKN2C,CDKN2D,CEBPA,CEP192,CEP85,CHAD,CHMP6,CHORDC1,CHP1,CIB1,CISH,CNKSR3,CNST,COX11,CRY2,CRYBA1,CSK,CTDSP1,CTDSP2,CTDSPL,DAB2IP,DACT1,DBNDD2,DCN,DDIT4,DEPTOR,DGKQ,DKK1,DLG1,DLG2,DLG3,DMD,DMTN,DNAJA1,DNAJC10,DNAJC15,DRD2,DRD3,DRD4,DTNBP1,DUS2,DUSP1,DUSP10,DUSP16,DUSP18,DUSP19,DUSP2,DUSP21,DUSP22,DUSP26,DUSP3,DUSP6,DUSP7,DUSP8,DUSP9,DVL1,DYNLL1,EDN1,EDNRB,EFNA1,EGLN1,EIF3A,ELFN1,ELFN2,ENG,ENPP1,EPHA1,EPHB2,ERRFI1,EZR,F2RL1,FABP4,FAM129A,FAM212A,FAM212B,FARP1,FBLN1,FBP1,FBXO7,FGFR1OP,FKBP15,FKBP1A,FKBP1B,FKTN,FLCN,FLRT1,FLRT2,FLRT3,FOXA2,FOXM1,FOXO1,GADD45A,GADD45B,GALR2,GALR3,GBA,GCKR,GFRA2,GGNBP2,GMFB,GMFG,GNAQ,GP1BA,GPATCH2,GPD1L,GPER1,GPR176,GPR87,GPRC5A,GPS1,GRB10,GREM1,GRM2,GRM3,GRM7,GRM8,GRXCR1,GSK3A,GSKIP,GSTP1,H2AFY,HDAC3,HDAC4,HEXIM1,HEXIM2,HGF,HHEX,HMGCR,HNRNPU,HPCA,HRH3,HSPB1,HSPH1,HTR1B,HTR1E,IBTK,IGBP1,IGF1R,IKBKB,IL1B,IL2,IL6,INCA1,INHA,INHBA,INPP5J,INPP5K,INSM1,IQGAP1,IRAK3,IRS2,ITCH,JUN,KAT2B,KIRREL1,KIRREL2,KLF4,KNL1,LATS1,LATS2,LAX1,LDLRAD4,LEMD2,LIF,LMO3,LMTK3,LPAR1,LRP5,LRP6,LRRC15,LRRC19,LRRC3,LRRC3C,LRRC4,LRRC4C,LRRC66,LRRK2,LRRTM1,LRRTM3,LRRTM4,LRTM1,LRTM2,LTB4R2,LYN,MAPK8IP1,MAPT,MARCO,MARF1,MARVELD3,MAS1,MASTL,MBIP,MECOM,MEN1,MICAL1,MLLT1,MLXIPL,MPHOSPH10,MSTN,MTOR,MVP,MYADM,MYC,MYO1D,MYOCD,MYOG,NCK1,NCK2,NCKAP1L,NF1,NF2,NIFK,NLRP6,NOG,NPM1,NPR3,NPRL2,NPY2R,NTF3,NTRK3,NUP62,OPRL1,OPRM1,OR56A1,OR56A4,OR5T3,P2RX7,PAFAH1B1,PAK2,PALM,PARD3,PARD6A,PARK7,PARP1,PARP14,PBK,PBLD,PCDH11X,PCIF1,PDE12,PDE2A,PDE4D,PDGFA,PDGFB,PDPK1,PDZD3,PER1,PFKFB1,PHB,PID1,PIK3IP1,PIK3R2,PIN1,PINK1,PKIA,PKIB,PKIG,PKMYT1,PKN1,PLEK,PLK1,PLPP3,PMEPA1,PODN,PODNL1,PPARA,PPARGC1A,PPEF2,PPIF,PPM1E,PPM1F,PPP1R15A,PPP1R15B,PPP1R16B,PPP1R1A,PPP1R1C,PPP1R26,PPP1R27,PPP1R35,PPP1R36,PPP1R37,PPP1R8,PPP2R5A,PPP4R4,PPP5C,PRDX3,PREX1,PRKAG2,PRKAR1A,PRKAR1B,PRKAR2B,PRKCA,PRKCD,PRKCZ,PRKDC,PRKN,PRKRIP1,PRR5L,PSCA,PSEN1,PSMD10,PTEN,PTPA,PTPN1,PTPN22,PTPRJ,PTPRR,PWP1,PYCARD,PYDC1,RANBP9,RAPGEF1,RASSF2,RB1,RBM26,RGN,RGS14,RGS2,RGS3,RGS4,RNF149,ROCK2,RPS6KA6,RPTOR,RRP1B,RTN4R,RTN4RL2,RUBCN,SAMSN1,SEMA4D,SERPINB3,SFI1,SFN,SFRP1,SFRP2,SH2D4A,SH3BP5,SH3RF2,SHB,SIRT1,SIRT2,SIRT3,SIRT6,SLC27A1,SLC7A14,SLC9A3R1,SLIT2,SMAD4,SMAD7,SMCR8,SMPD1,SMYD3,SNCA,SNX6,SOCS1,SOCS2,SOCS3,SOCS4,SOCS5,SOCS6,SOCS7,SORL1,SPINK1,SPOCD1,SPRED1,SPRED2,SPRY1,SPRY2,SPRY4,SRCIN1,SSTR4,STAP1,STK38,STRAP,SYNJ2BP,SYTL2,TARBP2,TARDBP,TBC1D10C,TERF2IP,TESC,TGFB1,TGFB2,THY1,TIGAR,TIMP3,TIPRL,TLR4,TMEM132D,TMEM225,TNF,TNFAIP3,TNIP1,TP73,TRAF3IP1,TRIB1,TRIB2,TRIB3,TSC2,TSG101,TSKS,TSPO,TWIST1,UBASH3B,UBN1,UCHL1,UVSSA,VPS25,VRK3,WARS,WDR81,WEE2,WNK1,WNK2,WWTR1,XDH,YWHAB,YWHAE,YWHAG,ZBED3,ZC3H12A,ZCCHC9,ZFYVE1,ZFYVE28,ZNF675	TetrapodAncestor	268.787
GO.Biological.Process	GO:0045936	negative.regulation.of.phosphate.metabolic.process	61	2.345814e-273	3.030088e-269	4.967357e-271	1.244315e+0	ABL1,ADAR,ADARB1,ADIPOQ,ADORA2A,ADRA2A,AHSG,AIDA,AJUBA,AKAP6,AKT1S1,AMBP,ANGPT1,APC,APLP1,APOC1,APOE,ARFGEF3,ARRB1,ARRB2,ASH1L,ASPN,ATF3,ATG14,BAG4,BAK1,BAX,BDKRB1,BDKRB2,BGN,BMP4,BMP7,C14orf166,C1QL4,C3orf33,C9orf72,CACTIN,CALM1,CALM2,CALM3,CAMK2N1,CAMK2N2,CAMSAP3,CASP3,CAV1,CAV3,CBL,CBLB,CBLC,CCDC8,CCNB1,CCR2,CD109,CD2BP2,CD300A,CDA,CDK5RAP1,CDKN1A,CDKN1B,CDKN1C,CDKN2A,CDKN2B,CDKN2C,CDKN2D,CEBPA,CEP192,CEP85,CHAD,CHMP6,CHORDC1,CHP1,CIB1,CISH,CNKSR3,CNST,COX11,CRY2,CRYBA1,CSK,CTDSP1,CTDSP2,CTDSPL,DAB2IP,DACT1,DBNDD2,DCN,DDIT4,DEPTOR,DGKQ,DKK1,DLG1,DLG2,DLG3,DMD,DMTN,DNAJA1,DNAJC10,DNAJC15,DRD2,DRD3,DRD4,DTNBP1,DUS2,DUSP1,DUSP10,DUSP16,DUSP18,DUSP19,DUSP2,DUSP21,DUSP22,DUSP26,DUSP3,DUSP6,DUSP7,DUSP8,DUSP9,DVL1,DYNLL1,EDN1,EDNRB,EFNA1,EGLN1,EIF3A,ELFN1,ELFN2,ENG,ENPP1,EPHA1,EPHB2,ERRFI1,EZR,F2RL1,FABP4,FAM129A,FAM212A,FAM212B,FARP1,FBLN1,FBP1,FBXO7,FGFR1OP,FKBP15,FKBP1A,FKBP1B,FKTN,FLCN,FLRT1,FLRT2,FLRT3,FOXA2,FOXM1,FOXO1,GADD45A,GADD45B,GALR2,GALR3,GBA,GCKR,GFRA2,GGNBP2,GMFB,GMFG,GNAQ,GP1BA,GPATCH2,GPD1L,GPER1,GPR176,GPR87,GPRC5A,GPS1,GRB10,GREM1,GRM2,GRM3,GRM7,GRM8,GRXCR1,GSKIP,GSTP1,H2AFY,HDAC3,HDAC4,HEXIM1,HEXIM2,HGF,HHEX,HMGCR,HNRNPU,HPCA,HRH3,HSPB1,HSPH1,HTR1B,HTR1E,IBTK,IGBP1,IGF1R,IKBKB,IL1B,IL2,IL6,INCA1,INHA,INHBA,INPP5J,INPP5K,INSM1,IQGAP1,IRAK3,IRS2,ITCH,JUN,KAT2B,KIRREL1,KIRREL2,KLF4,KNL1,LATS1,LATS2,LAX1,LDLRAD4,LEMD2,LIF,LMO3,LMTK3,LPAR1,LRP5,LRP6,LRRC15,LRRC19,LRRC3,LRRC3C,LRRC4,LRRC4C,LRRC66,LRRK2,LRRTM1,LRRTM3,LRRTM4,LRTM1,LRTM2,LTB4R2,LYN,MAPK8IP1,MAPT,MARCO,MARF1,MARVELD3,MAS1,MASTL,MBIP,MECOM,MEN1,MICAL1,MLLT1,MLXIPL,MPHOSPH10,MSTN,MTOR,MVP,MYADM,MYC,MYO1D,MYOCD,MYOG,NCK1,NCK2,NCKAP1L,NF1,NF2,NIFK,NLRP6,NOG,NPM1,NPR3,NPRL2,NPY2R,NTF3,NTRK3,NUP62,OPRL1,OPRM1,OR56A1,OR56A4,OR5T3,P2RX7,PAFAH1B1,PAK2,PALM,PARD3,PARD6A,PARK7,PARP1,PARP14,PBK,PBLD,PCDH11X,PCIF1,PDE12,PDE2A,PDE4D,PDGFA,PDGFB,PDPK1,PDZD3,PER1,PFKFB1,PHB,PID1,PIK3IP1,PIK3R2,PIN1,PINK1,PKIA,PKIB,PKIG,PKMYT1,PKN1,PLEK,PLK1,PLPP3,PMEPA1,PODN,PODNL1,PPARA,PPARGC1A,PPEF2,PPIF,PPM1E,PPM1F,PPP1R15A,PPP1R15B,PPP1R16B,PPP1R1A,PPP1R1C,PPP1R26,PPP1R27,PPP1R35,PPP1R36,PPP1R37,PPP1R8,PPP2R5A,PPP4R4,PPP5C,PRDX3,PREX1,PRKAG2,PRKAR1A,PRKAR1B,PRKAR2B,PRKCA,PRKCD,PRKCZ,PRKDC,PRKN,PRKRIP1,PRR5L,PSCA,PSEN1,PSMD10,PTEN,PTPA,PTPN1,PTPN22,PTPRJ,PTPRR,PWP1,PYCARD,PYDC1,RANBP9,RAPGEF1,RASSF2,RB1,RBM26,RGN,RGS14,RGS2,RGS3,RGS4,RNF149,ROCK2,RPS6KA6,RPTOR,RRP1B,RTN4R,RTN4RL2,RUBCN,SAMSN1,SEMA4D,SERPINB3,SFI1,SFN,SFRP1,SFRP2,SH2D4A,SH3BP5,SH3RF2,SHB,SIRT1,SIRT2,SIRT3,SIRT6,SLC27A1,SLC7A14,SLC9A3R1,SLIT2,SMAD4,SMAD7,SMCR8,SMPD1,SMYD3,SNCA,SNX6,SOCS1,SOCS2,SOCS3,SOCS4,SOCS5,SOCS6,SOCS7,SORL1,SPINK1,SPOCD1,SPRED1,SPRED2,SPRY1,SPRY2,SPRY4,SRCIN1,SSTR4,STAP1,STK38,STRAP,SYNJ2BP,SYTL2,TARBP2,TARDBP,TBC1D10C,TERF2IP,TESC,TGFB1,TGFB2,THY1,TIGAR,TIMP3,TIPRL,TLR4,TMEM132D,TMEM225,TNF,TNFAIP3,TNIP1,TP73,TRAF3IP1,TRIB1,TRIB2,TRIB3,TSC2,TSG101,TSKS,TSPO,TWIST1,UBASH3B,UBN1,UCHL1,UVSSA,VPS25,VRK3,WARS,WDR81,WEE2,WNK1,WNK2,WWTR1,XDH,YWHAB,YWHAE,YWHAG,ZBED3,ZC3H12A,ZCCHC9,ZFYVE1,ZFYVE28,ZNF675	TetrapodAncestor	268.519
GO.Biological.Process	GO:0071345	cellular.response.to.cytokine.stimulus	62	3.476346e-270	4.490396e-266	7.242574e-268	1.244462e+0	ABCC2,ABCD4,ABCG4,ACKR2,ACKR3,ACKR4,ACSL1,ADAMTS12,ADAMTS13,ADAMTS7,ADAR,ADIPOQ,ADIPOR1,ADIPOR2,AIF1,AIP,AKAP6,ALAD,ALOX15,ANKRD1,APOB,AQP4,ARF1,ARG1,ARHGEF2,ARID5B,ASPN,AXL,B3GNT2,BAD,BAG4,BBS4,BCAT2,BCLAF1,BGN,BIRC2,BIRC3,BOLA2B,BRCA1,BRWD1,BSPRY,BST2,BTK,CA1,CACTIN,CACYBP,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CANX,CARD14,CASP1,CCL1,CCL11,CCL13,CCL14,CCL15,CCL15-CCL14,CCL16,CCL17,CCL18,CCL19,CCL2,CCL21,CCL22,CCL23,CCL3,CCL3L3,CCL4,CCL4L2,CCL5,CCL7,CCL8,CCR1,CCR2,CCR3,CCR4,CCR5,CCR6,CCR7,CCR8,CCR9,CCRL2,CD27,CD300LF,CD40,CD44,CD58,CD70,CD74,CD86,CDC34,CDC42,CDC5L,CDIP1,CDK4,CDK9,CEBPA,CEBPB,CFL1,CHAD,CHI3L1,CHUK,CIB1,CIITA,CISH,CLCF1,CLDN1,CLDN18,CMKLR1,CNTF,CNTFR,COL1A1,COMMD7,CORO1A,CREB1,CRHBP,CRLF2,CSF1,CSF1R,CSF2RA,CSF2RB,CSF3,CSF3R,CSNK2B,CTH,CX3CL1,CX3CR1,CXCL1,CXCL10,CXCL11,CXCL13,CXCL2,CXCL3,CXCL5,CXCL6,CXCL8,CXCL9,CXCR1,CXCR2,CXCR3,CXCR4,CXCR5,CXCR6,CYBA,DAB2IP,DAPK1,DAPK3,DCN,DDX41,DHX9,DOCK8,DPYSL3,DTX1,DUOX1,DUOX2,EBI3,EDA,EDA2R,EDAR,EDARADD,EDN1,EDN2,EED,EFHC2,EGR1,EIF4A2,ELOC,ENSG00000249624,EPO,EPOR,EPRS,EPS8,EREG,ETV3,F3,FABP4,FAS,FASN,FER,FGF23,FGF4,FGG,FKBP1A,FLRT1,FLRT2,FLRT3,FOXC1,FOXF1,FOXH1,FZD4,GAPDH,GAS6,GATA3,GBA,GCLM,GFPT2,GHR,GLDC,GNPNAT1,GP1BA,GPD1,GPER1,GPR17,GPR35,GRB2,GREM2,GSK3A,GSTA2,HAMP,HAS2,HAX1,HCK,HCLS1,HDAC4,HIF1A,HIST1H3H,HIST1H3I,HIST1H3J,HIST2H3A,HIST2H3C,HIST2H3D,HMHB1,HNRNPA2B1,HNRNPU,HSP90AB1,HSPA5,HSPA9,HTRA2,IFI27,IFI35,IFI6,IFIT1,IFIT2,IFIT3,IFITM1,IFITM2,IFITM3,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNAR1,IFNAR2,IFNB1,IFNE,IFNG,IFNGR1,IFNGR2,IFNK,IFNLR1,IFNW1,IKBKB,IL10,IL10RA,IL10RB,IL11RA,IL12A,IL12B,IL12RB1,IL12RB2,IL13,IL13RA1,IL13RA2,IL15,IL15RA,IL17A,IL17C,IL17F,IL17RA,IL17RB,IL17RC,IL17RD,IL17RE,IL17REL,IL18,IL18BP,IL18R1,IL18RAP,IL1A,IL1B,IL1F10,IL1R1,IL1R2,IL1RAP,IL1RAPL2,IL1RL1,IL1RL2,IL20RA,IL20RB,IL21R,IL22RA1,IL22RA2,IL23A,IL23R,IL24,IL27,IL27RA,IL2RB,IL2RG,IL31RA,IL36A,IL36B,IL36G,IL37,IL3RA,IL5,IL5RA,IL6,IL6R,IL6ST,IL7,IL7R,IL9,INPP5K,IRAK1,IRAK3,IRAK4,IRF1,IRF2,IRF3,IRF4,IRF6,IRF7,IRF8,IRF9,IRS1,IRS2,ISG15,ISG20,ITGA4,JAGN1,JAK2,JAK3,JARID2,KARS,KCNJ11,KDM3A,KDM5B,KEAP1,KHSRP,KLF2,KLF4,KLF5,KRAS,LCK,LCN2,LCP1,LEF1,LEP,LEPR,LGALS9,LIFR,LMNB1,LRAT,LRCH1,LRP8,LRRC15,LRRC19,LRRC3,LRRC3C,LRRC4,LRRC4C,LRRC66,LRRTM1,LRRTM3,LRRTM4,LRTM1,LRTM2,LTB,LTBR,MAP3K14,MAP3K5,MAPK1,MAPK3,MAT2A,MCF2,MCM2,MID1,MIF,MKKS,MME,MPC1,MPL,MRC1,MRPL15,MSC,MSN,MST1R,MTAP,MTF2,MX1,MX2,MYBL2,MYLK3,MYNN,NCAM1,NCL,NEFH,NFIL3,NFKB1,NFYB,NGFR,NKX3-1,NKX6-1,NLRP7,NMI,NOS2,NPR2,NR5A2,NUMBL,OAS1,OASL,OCLN,OCSTAMP,OSM,OSMR,OTUB1,P4HB,PADI2,PAK2,PARP16,PCK1,PCK2,PDCD10,PDE12,PDE1B,PDE2A,PDGFB,PF4,PF4V1,PFKP,PHB,PID1,PIGA,PIK3C3,PIK3CA,PIK3R1,PIK3R2,PITPNA,PLA2G10,PLCB1,PLP2,PLVAP,PML,PMM1,PNPT1,PODN,PODNL1,POU4F1,PPARGC1A,PPBP,PRDM5,PRKCD,PRLR,PRPF8,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTAFR,PTGIS,PTK2B,PTP4A3,PYCARD,PYDC1,RALA,RAP1B,RARG,RC3H1,RELA,RELT,RFX2,RIF1,RIPK1,RIPOR2,RNASEL,RNF138,RNMT,RPL13A,RPL3,RPLP0,RPS16,RPS27A,RPS3,RPS6KA4,RPS6KA5,RSAD2,RTN4R,RTN4RL2,SAMHD1,SERPINB2,SFRP1,SHC1,SHMT1,SHPK,SIRT1,SLC25A5,SLC27A1,SMAD4,SMAD7,SMARCA4,SNRNP70,SNRPA1,SNX10,SOCS1,SOCS2,SOCS3,SOCS4,SOCS5,SOCS6,SOCS7,SOD1,SOD2,SOX1,SOX17,SOX9,SP100,SPOCK2,SPRY2,SRM,SRSF7,SSTR1,ST18,ST3GAL6,STAR,STAT1,STAT2,STAT4,STAT6,SYNCRIP,SYNGR1,TALDO1,TCL1A,TCP1,TDGF1,TEX14,TFPI,TFRC,THBS1,THPO,TJP2,TLE4,TLR3,TMEM173,TNF,TNFRSF10A,TNFRSF10B,TNFRSF10C,TNFRSF10D,TNFRSF11A,TNFRSF11B,TNFRSF12A,TNFRSF13B,TNFRSF13C,TNFRSF14,TNFRSF17,TNFRSF18,TNFRSF19,TNFRSF1A,TNFRSF1B,TNFRSF21,TNFRSF25,TNFRSF4,TNFRSF8,TNFRSF9,TNFSF11,TNFSF12,TNFSF13,TNFSF13B,TNFSF14,TNFSF15,TNFSF18,TNFSF8,TNFSF9,TNIP2,TPR,TRADD,TRAF2,TRAF3,TRAF6,TRIM21,TRIM22,TRIM25,TRIM34,TRIM38,TRIM5,TRIM6,TRIM62,TRIM68,TRIM8,TRPV1,TSLP,TUBA1B,TWISTNB,TXNDC17,UBC,UBE2G2,UPF1,USP10,VCAM1,VEGFC,WDR35,WNT5A,XAF1,XBP1,XCL1,XCL2,XCR1,XRCC5,YBX3,YY1,ZC3H12A,ZC3H15,ZFAND6,ZFP36,ZFP36L1,ZFP36L2,ZNF675	TetrapodAncestor	265.348
GO.Biological.Process	GO:1903706	regulation.of.hemopoiesis	63	4.531626e-269	5.853501e-265	9.291272e-267	1.317145e+0	ABL1,ACE,ACIN1,ACVR1B,ACVR2A,ADA,ADAM8,ADIPOQ,AGER,AGO1,AGO3,AGO4,ANKLE1,ANKRD54,ANXA1,AP3D1,ASH2L,ATP11C,ATP6AP1,ATXN1L,AXL,BAD,BCL6,BGLAP,BMP4,BRAF,BTK,C1QC,C8orf4,CA2,CAMK4,CARD11,CARTPT,CASP8,CBFB,CCL19,CCL3,CCR1,CD101,CD2,CD27,CD28,CD46,CD74,CD80,CD83,CD86,CDC73,CDK6,CEBPB,CIB1,CLDN18,CR1,CREB1,CSF1,CSF3,CSF3R,CTLA4,CTNNB1,CUL4A,CYP26B1,DLL1,DPY30,DROSHA,DTX1,DUSP10,EIF2AK2,EIF6,EP300,ERBB2,ESRRA,ETS1,FADD,FAM210B,FANCA,FAS,FBXO7,FES,FLCN,FLT3LG,FOS,FOXC1,FOXJ1,FOXN1,FOXP3,FSHB,FSHR,FSTL3,GABPA,GAS6,GATA2,GATA3,GLI2,GLI3,GNAS,GP1BA,GPR171,GPR55,GPR68,H3F3A,HAX1,HCLS1,HDAC1,HES1,HES5,HIF1A,HIST1H3H,HIST1H3I,HIST1H3J,HIST1H4J,HIST1H4K,HIST1H4L,HIST2H3A,HIST2H3C,HIST2H3D,HIST2H4B,HIST4H4,HLX,HMGB1,HMGB2,HMGB3,HSPA9,IFNA2,IFNB1,IFNG,IFNL1,IHH,IKZF3,IL12A,IL12B,IL12RB1,IL15,IL17A,IL18,IL1RL2,IL2,IL20,IL23A,IL23R,IL27,IL34,IL36B,IL4,IL5,IL6,IL7,IL7R,INHA,INHBA,INPP5D,IRF1,IRF4,IRF7,ISG15,ITCH,ITGA2B,ITPKB,JAG1,JAK3,JUN,KAT2B,KITLG,KLF10,KLF13,KMT2B,KMT2C,KMT2E,L3MBTL1,LEF1,LEO1,LEP,LGALS3,LGALS9,LHCGR,LIF,LILRB2,LILRB4,LMO2,LOXL3,LRRC17,LYN,MAFB,MAPK14,MEF2C,MEIS1,MEIS2,METTL3,MIXL1,MMP14,MOV10,MTOR,MYB,MYC,MYL9,NCKAP1L,NDFIP1,NF1,NFAM1,NFATC2,NFKBID,NME1,NME2,NOTCH1,NR4A3,OCSTAMP,PAF1,PCID2,PDCD2,PF4,PGLYRP1,PGLYRP2,PGLYRP3,PIK3R1,PIK3R6,PNP,POU4F1,PPARGC1B,PPP2R3C,PRDM1,PRELID1,PRKCA,PRKCB,PRKCQ,PRKCZ,PRMT1,PRMT6,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTK2B,PURB,RAB7B,RAG1,RARA,RARG,RASGRP1,RASSF2,RB1,RBBP5,RBFOX2,RC3H1,RIPK1,RIPK2,RNF41,ROR2,RPS27A,RUNX1,SART1,SASH3,SCIN,SETD1A,SFRP1,SHB,SIGLEC15,SLC46A2,SLC9B2,SMAD7,SMAP1,SOCS1,SOCS5,SOD1,SOS1,SOX13,SPI1,SPINK5,STAT1,SYK,TAL1,TCF3,TESC,TESPA1,TFE3,TGFB1,TGFBR2,THBS1,THPO,TJP2,TLR3,TLR4,TLR9,TMEM131L,TMEM176A,TMEM176B,TMEM178A,TMEM64,TNF,TNFRSF18,TNFSF11,TNFSF18,TNFSF9,TNRC6A,TNRC6B,TNRC6C,TP73,TRAF6,TRIB1,UBASH3B,UBC,VNN1,WDR5,WDR61,XBP1,YAP1,YTHDF2,ZAP70,ZBTB1,ZBTB16,ZBTB7B,ZC3H8,ZEB1,ZFP36,ZFP36L1,ZFP36L2,ZFPM1,ZMIZ1,ZNF16,ZNF675,ZNF683	TetrapodAncestor	264.233
GO.Biological.Process	GO:0071396	cellular.response.to.lipid	64	5.477119e-268	7.074795e-264	1.105437e-265	1.267025e+0	AACS,ABCA1,ABCB4,ABCC2,ABHD2,ABL1,ABL2,ACACA,ADAM9,ADAMTS13,ADCY2,ADCY3,ADCY5,ADCYAP1,ADNP2,AGTR2,AICDA,AIFM1,AKAP8,ANKRD1,ANXA1,APOB,AQP1,AR,ARG1,ARID1A,ATP1A1,ATP1A2,ATP2B1,AXL,BAD,BCR,BGLAP,BMP4,BMP7,BRCA1,BRINP1,BRINP2,BRINP3,CACTIN,CALCOCO1,CALR,CARD16,CARD17,CARM1,CASP1,CASP9,CASR,CCL2,CCL3,CCL5,CCNA2,CCNB1,CCNE1,CCR5,CD14,CD180,CD36,CD40,CD6,CD80,CD86,CDC73,CDK19,CDK4,CDK6,CDK7,CEBPB,CEBPE,CFLAR,CFTR,CLDN1,CMPK2,COL1A1,CPEB1,CPS1,CPT1A,CREB1,CRHBP,CSF3,CTNNB1,CX3CR1,CXCL10,CXCL16,CXCL6,CXCL8,CYP24A1,CYP26B1,CYP7A1,DAB2IP,DAXX,DDIT4,DDX17,DDX18,DDX5,DDX54,DGAT2,DNAJA1,DNM1L,DNMT3B,DYNAP,E2F1,EDN1,EDNRB,EFNA5,EGFR,EGLN2,EIF4E,EIF4EBP1,ELK1,EPHA3,EPHX1,ERRFI1,ESR1,ESR2,ESRRA,ESRRB,ESRRG,FAM210B,FBXO32,FDX1,FFAR2,FFAR3,FGF23,FGFR2,FHL2,FIS1,FKBP4,FOXO1,FZD10,FZD4,FZD7,GDAP1,GHSR,GJB3,GNAI1,GNG2,GPER1,GPLD1,GRIP1,GSTP1,H2AFZ,HAMP,HAVCR2,HCK,HDAC2,HDAC5,HDAC8,HEY1,HMGB2,HMGCS1,HNF4A,HNF4G,HNRNPD,HNRNPU,HSF1,HTRA2,ID3,IFNB1,IFNG,IL10,IL12A,IL12B,IL15,IL18,IL1B,IL24,IL6,INHBA,IRAK1,IRF3,IRF8,IRGM,ISL1,ITGA2,JAK2,KAT5,KCNK4,KCNMB1,KDM3A,KIF18A,KLF4,KLF9,KLRK1,KRT13,LBP,LCN2,LDLR,LEF1,LEP,LILRB2,LITAF,LPAR1,LRP6,LRP8,LTK,LY96,LYN,MAPK1,MAPK14,MAPK3,MAPK8,MED13,MED14,MED17,MED24,MED30,MED4,MEF2C,METTL21C,MGARP,MLC1,MRC1,MSN,MSTN,MSX2,MTDH,MYB,MYOD1,MYOG,NCOA1,NCOA3,NCOA4,NCOA6,NFATC4,NFKB1,NFKBIB,NKX3-1,NLRP7,NME1,NME2,NOS2,NOS3,NPAS4,NPC1,NR0B1,NR0B2,NR1D1,NR1D2,NR1H2,NR1H3,NR1H4,NR1I2,NR2C1,NR2C2,NR2E3,NR2F6,NR3C1,NR4A1,NR4A2,NR4A3,NR5A2,NRIP1,NTRK3,NUGGC,OPRK1,OR51E2,OSR1,P2RY4,P2RY6,PABPN1,PADI2,PAF1,PAQR5,PAQR6,PAQR7,PAQR8,PAX2,PCK1,PDE4B,PDE4D,PDK3,PENK,PGR,PGRMC2,PHB,PHEX,PIAS1,PIAS2,PID1,PIM1,PLAA,PLPP1,PLSCR4,PMEPA1,POU4F1,PPARA,PPARD,PPARG,PPARGC1A,PPARGC1B,PRKAA1,PRKAA2,PRKCE,PRPF8,PTAFR,PTCH1,PTGDR,PTGER2,PTGER4,PTGFR,PTK2B,PTK7,PTN,PTPN22,PYCARD,RARA,RARB,RARG,RASGRP4,RB1,RBFOX2,RBM14,RELA,REST,RET,RIPK2,RNF14,RNF4,ROCK2,RORB,RORC,RUVBL2,RWDD1,RXRA,RXRB,RXRG,SAFB,SCARB1,SETX,SFRP1,SHPK,SLC6A4,SMARCD1,SMO,SMYD3,SNRNP70,SNW1,SOX10,SOX9,SPON2,SPP1,SRC,SRD5A1,SREBF1,SSTR1,SSTR2,SSTR3,SSTR4,SSTR5,STAP1,STAR,STC1,STRA8,T,TADA3,TBX1,TBXA2R,TEAD2,TESC,TFPI,TGFB1,TGFB1I1,THRA,THRAP3,THRB,TICAM1,TICAM2,TLR2,TLR4,TLR5,TNC,TNF,TNFAIP3,TNFRSF1B,TNIP1,TNIP2,TNIP3,TRAF6,TRIP4,TSPO,TWF2,UBE2L3,UBE3A,UBR5,UCP1,UGT1A1,UPF1,USP8,VDR,WDR35,WNT10B,WNT11,WNT3,WNT3A,WNT5A,WNT6,WNT7B,WNT8B,WNT9A,WNT9B,XBP1,XRCC5,YAP1,YES1,YWHAH,ZC3H12A,ZFP36,ZFP36L1,ZFP36L2,ZNF703	TetrapodAncestor	263.15
GO.Biological.Process	GO:0007169	transmembrane.receptor.protein.tyrosine.kinase.signaling.pathway	65	2.678778e-267	3.460178e-263	5.323350e-265	1.255573e+0	ABI1,ABL1,ABL2,ACTR2,ACTR3,ADRB2,AHI1,AKT1S1,AKT2,ALK,ANGPT1,ANGPT2,ANGPT4,ANGPTL1,ANOS1,AP2A1,AP2A2,AP2B1,AP2M1,AP2S1,AP3S1,APC,APH1A,APH1B,APPL1,AREG,ARHGEF7,ARID5B,ARPC1A,ARPC1B,ARPC2,ARPC4,ARPC5,ATP6AP1,ATP6V0A4,ATP6V0B,ATP6V0C,ATP6V0D1,ATP6V0D2,ATP6V0E1,ATP6V0E2,ATP6V1B1,ATP6V1B2,ATP6V1C1,ATP6V1C2,ATP6V1D,ATP6V1E1,ATP6V1E2,ATP6V1G1,ATP6V1G3,ATP6V1H,AXL,BAIAP2L2,BCAR1,BCR,BDKRB2,BDNF,BLK,BLNK,BMPR2,BMX,BTC,BTK,C2CD5,CASP3,CAV2,CBL,CBLB,CCL2,CD3E,CD3EAP,CD7,CD8A,CD8B,CDC42,CDK5R1,CEP57,CHRNA3,CLNK,CNKSR1,COL1A1,COL4A3,COL4A5,CPNE3,CRIM1,CRK,CSF1,CSF1R,CSH1,CSK,CSPG4,CSRNP1,CTGF,CUL5,CYBA,CYBB,CYFIP1,CYFIP2,DAB2IP,DDIT4,DDR1,DDR2,DGKD,DGKQ,DNM1,DOK1,DOK2,DOK5,EFEMP1,EFNA1,EFNA3,EFNA4,EFNA5,EFNB1,EFNB2,EFNB3,EGF,EGFR,EIF2AK3,EIF4EBP1,ELMO1,ELMO2,ENSG00000251246,ENSG00000278139,ENSG00000282278,EPHA1,EPHA10,EPHA2,EPHA3,EPHA4,EPHA5,EPHA6,EPHA7,EPHA8,EPHB1,EPHB2,EPHB3,EPHB4,EPHB6,EPS15,EPS8,ERBB2,ERBB4,EREG,ESRP1,ESRP2,FAM83B,FAT4,FER,FES,FGF1,FGF10,FGF12,FGF16,FGF17,FGF18,FGF19,FGF2,FGF20,FGF21,FGF22,FGF23,FGF3,FGF4,FGF6,FGF7,FGF9,FGFBP1,FGFR1,FGFR2,FGFR3,FGFR4,FGFRL1,FGR,FIBP,FLRT1,FLRT2,FLRT3,FLT1,FLT4,FOXC1,FOXC2,FOXO1,FOXO4,FRK,FRS2,FRS3,GAB1,GAB2,GAREM1,GFRA1,GFRA2,GFRA4,GH1,GH2,GHR,GIGYF1,GIGYF2,GPLD1,GRAP,GRAP2,GRB10,GRB2,GRB7,GREM1,GRIN1,GRIN2B,GSK3A,GTF2F1,GTF2F2,HAP1,HBEGF,HCK,HGF,HNRNPH1,HNRNPM,HPN,HRAS,HSPB1,IDE,IGF1,IGF1R,IGF2,IGF2R,IL31RA,INS,INSRR,IQGAP1,IRS1,IRS2,IRS4,ITGAV,ITK,ITSN1,JAK2,JAK3,KALRN,KIF16B,KL,KRAS,LCK,LCP2,LTK,LYN,MAPK1,MAPK11,MAPK13,MAPK14,MAPK3,MAPKAPK2,MAPKAPK3,MATK,MET,MMP9,MPZL1,MST1,MST1R,MTSS1,MUC20,MUSK,MVP,MYO1C,MYO1E,NCBP1,NCBP2,NCF1,NCF2,NCF4,NCK1,NCK2,NCKAP1,NCKAP1L,NCSTN,NDEL1,NDST1,NGEF,NGF,NGFR,NOG,NRAS,NRG1,NRG2,NRG3,NRG4,NRP1,NRP2,NRTN,NTF3,NTF4,NTRK1,NTRK2,NTRK3,PAG1,PAK1,PAK2,PAK3,PDCD6,PDGFA,PDGFB,PDGFC,PDGFD,PDGFRB,PDGFRL,PDK2,PDPK1,PHIP,PIGR,PIK3C2A,PIK3CA,PIK3R1,PIK3R2,PIK3R3,PLAT,PLCB1,PLCE1,PLCG1,PLEKHA1,POLR2A,POLR2B,POLR2C,POLR2D,POLR2F,POLR2G,POLR2H,POLR2I,POLR2J,POLR2L,PRKCA,PRKCZ,PRKD1,PRKD2,PRL,PRLR,PSEN1,PSEN2,PSENEN,PTEN,PTK2,PTK2B,PTPN1,PTPN11,PTPN12,PTPRA,PTPRG,PTPRJ,PTPRR,PTPRT,PXN,RAB14,RAC1,RAF1,RAPGEF1,RAPGEF2,RASA1,RASGRP4,RASSF2,RBFOX2,REPS2,RET,RGS14,RHOQ,ROCK2,ROR2,ROS1,RPE65,RPS27A,RPS6KA5,SDC2,SDCBP,SETX,SGPL1,SH2B2,SH2D2A,SH2D6,SHB,SHC1,SHC2,SHC3,SHCBP1,SIPA1L1,SIRT2,SLA,SLA2,SLC2A8,SLC30A10,SMARCC1,SOCS2,SOCS5,SOCS7,SOGA1,SORBS1,SOS1,SOX9,SPRED1,SPRED2,SRC,SREBF1,SS18,STAP1,STMN1,STUB1,STXBP4,STYK1,SULF2,SYK,TCIRG1,TEC,TEK,TGFB1,TIA1,TIAL1,TIAM1,TIPARP,TNK2,TRAT1,TRIM71,TSC2,TXK,TXNIP,UBASH3B,UBC,VAV1,VAV2,VAV3,VEGFA,VEGFB,VEGFC,VEGFD,VIL1,WASF2,YES1,ZAP70,ZFAND5,ZFYVE27,ZNF106	TetrapodAncestor	262.461
GO.Biological.Process	GO:2000027	regulation.of.organ.morphogenesis	66	1.104417e-264	1.426575e-260	2.161478e-262	1.348337e+0	ABL1,AGT,AGTR2,AHI1,AJAP1,AMELX,ANKRD6,AP2A1,AP2A2,AP2B1,AP2M1,AP2S1,AR,ARHGEF19,ARRB2,ASPN,B4GALT1,BASP1,BAX,BCL2,BCOR,BMP10,BMP2,BMP4,BMP7,BMPR1A,BMPR2,C4orf26,CARM1,CAV3,CD34,CDC42,CELSR1,CELSR2,CFLAR,CHAD,CITED1,CITED2,CLTC,CNTF,CPB2,CSF1,CTNNB1,DAAM1,DAB2,DACT1,DKK1,DMP1,DVL1,DVL3,EDN1,ENG,ESR1,ETV5,EYA1,FBXW7,FGF1,FGF10,FGF7,FGFR1,FGFR2,FOXC1,FOXC2,FOXP2,FRS2,FZD1,FZD2,FZD3,FZD4,FZD5,FZD6,FZD7,GATA3,GDNF,GPC3,GPC4,GPC6,GREM1,GRHL3,HAND2,HES1,HGF,HNF1B,HPN,IFNG,ISL1,LGR4,LHX1,LIF,LIMS2,MAGI2,MESP1,MKS1,MLLT3,MMP20,MSX1,MYC,NFIB,NOG,NOTCH1,NPHP3,NUMB,PARD6A,PAX2,PAX8,PAX9,PDGFA,PFN1,PIM1,POR,PRICKLE1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTK7,PTN,RAC1,RBPJ,RNF207,ROR2,RPS27A,RSPO2,RSPO3,RUNX2,RXRA,RYK,SAPCD2,SEC24B,SEMA3C,SFRP1,SFRP2,SIX2,SMAD4,SMO,SMURF1,SMURF2,SNAI2,SOX17,SOX8,SOX9,SPRY1,SRSF6,STAT1,SULF2,TACSTD2,TBX1,TBX2,TBX5,TFAP2A,TGFB1,TGFB2,TGFBR1,TGFBR2,TIAM1,TNF,TNFAIP3,TNFRSF11B,TWIST1,UBC,VANGL1,VANGL2,VDR,VEGFA,WNT1,WNT10A,WNT11,WNT3A,WNT4,WNT5A,WNT6,WNT9B,XBP1,ZNRF3	TetrapodAncestor	259.846
GO.Biological.Process	GO:0048646	anatomical.structure.formation.involved.in.morphogenesis	67	1.601386e-264	2.068510e-260	3.087329e-262	1.187831e+0	AAMP,ABI1,ABL1,ACKR3,ACTN1,ACVR2B,ACVRL1,ADA,ADAM15,ADAM8,ADAMTS1,ADGRA2,ADGRB3,ADGRG1,ADGRG6,ADIPOR2,ADM2,AGGF1,AGTPBP1,AHI1,ALDH1A3,ALX1,AMELX,ANGPT1,ANGPT2,ANGPT4,ANGPTL4,ANK2,ANKRD1,ANPEP,APAF1,APOD,APOLD1,AR,ARHGAP22,ARHGAP24,ARHGAP35,ARID1A,ARL6,ATM,ATOH8,ATP8A2,ATP8B1,ATPIF1,AXIN2,B4GALT1,BBS4,BCAS3,BCL10,BCL2L11,BCL3,BCL6,BMP10,BMP4,BMP5,BMP7,BMPER,BMPR1A,BMPR2,BYSL,C16orf45,C1GALT1,CACNA1H,CALB1,CALCRL,CAPN2,CASP3,CASP9,CASQ1,CASQ2,CAV1,CAV3,CBLN1,CCBE1,CCDC136,CCL2,CCNB1IP1,CD109,CD34,CD9,CDC42,CDC73,CDH13,CDK5,CDK5R1,CDK5R2,CDON,CELSR1,CEND1,CFL1,CFL2,CFLAR,CHRD,CIB1,CITED2,CLEC1B,CNNM4,CNOT2,CNOT3,COBL,COL11A1,COL12A1,COL15A1,COL18A1,COL1A1,COL2A1,COL6A1,COL7A1,COL8A1,COL8A2,CRB2,CSF3R,CSPG4,CSRP3,CTGF,CTNNB1,CUL3,CX3CL1,CXCL13,CXCL8,CXCR3,CYP1B1,CYR61,DAB2IP,DCANP1,DCHS1,DEAF1,DKK1,DLC1,DLL1,DLL3,DLL4,DLX5,DSCAM,DUSP1,DUSP2,DVL1,DVL3,DYRK1B,E2F7,E2F8,ECSCR,EDA,EDAR,EDN1,EFNA1,EFNB2,EGF,EGFL7,EGLN1,EGR2,EGR3,EIF2AK3,ELF5,ELK3,ENG,ENPEP,ENSG00000259753,EOMES,EP300,EPAS1,EPB41L3,EPB41L5,EPGN,EPHA1,EPHA2,EPHB1,EPHB2,EPHB3,EPHB4,ERAP1,ERCC1,ERCC2,EREG,ERG,ERVFRD-1,ERVW-1,ESM1,ETS1,ETS2,EXOC4,EXT2,EYA1,EYA2,FABP9,FAIM2,FAM20A,FAM20C,FBN2,FER1L5,FGF1,FGF10,FGF18,FGF2,FGF6,FGF9,FGFR1,FGFR2,FHL2,FHOD3,FJX1,FKBP1A,FLT1,FLT4,FMN1,FMNL3,FN1,FOXA1,FOXA2,FOXC1,FOXC2,FOXF1,FOXH1,FOXN4,FOXO1,FRS2,FUZ,FZD1,FZD2,FZD3,FZD5,FZD6,FZD8,GAB1,GATA3,GATA6,GBX2,GDF2,GDF3,GDNF,GLI2,GLI3,GNA13,GNAS,GPC1,GPLD1,GPR4,GRB2,GREM1,GRHL2,GRHL3,GRID2,GSC,HAND1,HAND2,HDAC1,HDAC2,HERC1,HES5,HES7,HESX1,HEY1,HEY2,HEYL,HHEX,HIF1A,HIF3A,HIPK1,HIPK2,HMGA2,HMOX1,HNF1B,HOXA1,HPSE,HRG,HS6ST1,HSBP1,HSPG2,HTRA1,ID1,IFT172,IFT52,IFT57,IGSF22,IHH,IL18,INHBA,ISL1,ITGA2,ITGA3,ITGA4,ITGA5,ITGA7,ITGA8,ITGAV,ITGB1,ITGB2,ITGB4,ITGB5,JAG1,JAM3,JMJD6,JUN,JUNB,KBTBD8,KCNH1,KDM2B,KDM4C,KDM6A,KDM6B,KIF16B,KIF20B,KIF26B,KLF4,KLF5,KLHL12,KLHL6,KNL1,KRIT1,KRT19,LAMA3,LAMA5,LAMB1,LAMB3,LATS1,LDB3,LEF1,LEMD2,LEMD3,LEO1,LEP,LEPR,LFNG,LHX1,LHX2,LHX5,LMO4,LMOD1,LMOD3,LOXL2,LRP6,LUZP1,MAFB,MAPK1,MAPK14,MAPK3,MBOAT7,MCAM,MEF2A,MEF2C,MEIS1,MEOX1,MEOX2,MESP1,MESP2,MFGE8,MFN2,MIB1,MIXL1,MKS1,MMP14,MMP15,MMP19,MMP20,MMP8,MMP9,MMRN2,MSGN1,MSX1,MSX2,MTHFD1,MTHFD1L,MTMR2,MTPN,MYBPC1,MYBPC2,MYBPC3,MYBPH,MYDGF,MYF6,MYH3,MYH6,MYH9,MYLK3,MYMK,MYMX,MYOD1,MYOF,MYOM2,MYOM3,MYOZ3,MYPN,NAA15,NANOG,NBEAL2,NCL,NCMAP,NDNF,NEBL,NECTIN1,NECTIN2,NEUROG1,NF2,NFASC,NFATC4,NFIB,NFKB2,NKX2-5,NKX3-1,NKX3-2,NLE1,NOG,NOLC1,NOS1,NOS3,NOTCH1,NOTCH3,NOTCH4,NOV,NOX5,NPHS1,NR4A1,NR4A3,NRG3,NRP1,NRP2,NTF4,NUS1,OBSCN,OLFM1,OSR1,OTULIN,OTX2,OVOL2,PAF1,PAFAH1B1,PALB2,PAX2,PAX8,PCDH8,PDCD10,PDCD6,PDCL3,PDGFA,PDGFRB,PDPN,PEF1,PERP,PFN1,PHACTR4,PHOX2A,PIK3CA,PIK3CG,PIK3R6,PIKFYVE,PITX2,PKNOX1,PLA2G3,PLCD3,PLEKHO1,PLXDC1,PLXNA2,PLXNB2,PLXND1,PODXL,POFUT2,POGLUT1,PPARA,PPARGC1B,PPP3CB,PRCP,PRICKLE1,PRKACA,PRKAR1A,PRKCA,PRKD1,PRKD2,PRKDC,PRKX,PROK1,PROK2,PROM1,PROX1,PSEN1,PTCH1,PTEN,PTF1A,PTK2,PTK2B,PTK7,PTPN11,PTPN14,PTPRB,PTPRM,RALA,RAMP1,RAMP2,RAPGEF3,RARA,RARG,RASIP1,RBM46,RBP4,RBPJ,RDH10,RDH13,RELN,RET,RFX2,RIPPLY1,RIPPLY2,RNF213,ROBO1,ROBO4,ROR2,RPL7L1,RRP7A,RS1,RSPO3,RTF1,S100A7,S1PR1,SAT1,SCG2,SCRIB,SCX,SDC4,SDK1,SDK2,SEC24B,SEMA3C,SEMA3E,SEMA4A,SEMA4C,SEMA5A,SETD2,SF3B6,SFRP1,SFRP2,SH2D2A,SH3PXD2A,SHB,SHC1,SHROOM3,SIRT1,SIX2,SKI,SKIL,SLC12A6,SLC24A4,SLC34A1,SLC40A1,SLIT2,SMAD2,SMAD4,SMO,SNAI1,SNAI2,SOCS7,SOX11,SOX17,SOX18,SOX2,SOX4,SOX7,SOX8,SOX9,SPACA1,SPINT1,SRF,SRPK2,SRPX2,SSBP3,ST14,STAB2,STIL,STIM1,STK4,STRA6,SUFU,SYK,T,TAL1,TBC1D20,TBPL1,TBX1,TBX2,TBX20,TBX3,TBX5,TBX6,TCF15,TCF21,TCOF1,TDGF1,TEAD2,TEK,TENM4,TFAP2A,TFAP2B,TGFB1,TGFB2,TGFBI,TGFBR1,TGFBR2,TGM2,THBS1,THBS3,THSD7A,THY1,TIE1,TIFAB,TLR2,TLX2,TMED2,TMEM100,TMEM2,TMOD1,TMOD2,TMOD3,TMOD4,TMPRSS6,TNFRSF12A,TNFSF12,TNMD,TOPORS,TP63,TRAF6,TRIM71,TSC2,TSPAN12,TTN,TULP3,TWIST1,TXNDC8,TXNRD1,TYMP,UBP1,UGT8,UNC5B,VANGL2,VASH1,VASH2,VASP,VAV2,VAV3,VEGFA,VEGFB,VEGFC,VEGFD,VEZF1,VHLL,VTN,WARS,WASF2,WDR1,WDR72,WLS,WNT1,WNT10B,WNT11,WNT16,WNT3,WNT3A,WNT4,WNT5A,WNT6,WNT7A,WNT8A,WNT9B,XBP1,XRCC2,ZC3H12A,ZFPM1,ZNF385A,ZP3,ZPBP2	TetrapodAncestor	259.684
GO.Biological.Process	GO:0032101	regulation.of.response.to.external.stimulus	68	1.512178e-263	1.953280e-259	2.872471e-261	1.233893e+0	A2M,ABAT,ABCC8,ABR,ACE2,ACP5,ADA,ADAM8,ADAMTS12,ADAMTS18,ADCYAP1,ADGRA2,ADIPOQ,ADORA1,ADORA2A,ADORA2B,AGER,AGT,AGTR1,AHSG,AIF1,AJAP1,ANGPT2,ANKRD17,ANO6,ANXA1,AP1B1,AP1G1,AP1M1,AP1M2,AP1S2,AP1S3,AP2A1,AP2A2,AP2B1,AP2M1,AP2S1,APOA1,APOBEC3F,APOBEC3G,APOD,APOE,APOH,ARF1,ARG1,ARG2,ARTN,ASH1L,ASIC2,ATP6V1H,BAP1,BBS4,BCL6,BCR,BIRC2,BIRC3,BMP6,BMPR2,BRAF,BRD4,BST1,BTK,C1QA,C1QB,C1QBP,C1QC,C1QTNF1,C1QTNF12,C1QTNF3,C3,C3AR1,C4A,C4B,C4BPA,C4BPB,C5,C5orf30,C6,C7,C8A,C8B,C8G,C9,CACTIN,CALCRL,CALM1,CALR,CAMK1D,CARD16,CARTPT,CASK,CASP1,CASP4,CASP5,CASR,CAV1,CCK,CCL1,CCL19,CCL2,CCL21,CCL3,CCL4,CCL5,CCL7,CCR1,CCR2,CCR4,CCR6,CCR7,CD109,CD180,CD19,CD247,CD28,CD34,CD36,CD46,CD47,CD55,CD59,CD6,CD74,CD81,CD8B,CD9,CDH13,CDK19,CERS2,CFH,CFHR1,CFHR2,CFHR4,CFHR5,CFI,CFP,CHID1,CLASP1,CLASP2,CLEC4M,CLU,CMKLR1,CNGA1,CNGB1,CNR1,CNR2,CNTF,CORO1B,CPB2,CPN1,CPN2,CR1,CR2,CREB3,CREB3L3,CRK,CSF1,CTNNA2,CX3CL1,CX3CR1,CXCL1,CXCL10,CXCL11,CXCL13,CXCL14,CXCL2,CXCL3,CXCL5,CXCL6,CXCL8,CXCL9,CXCR4,CYBA,CYP19A1,CYP27B1,DAPK2,DDT,DDX58,DDX60,DHX9,DMTN,DOCK2,DRD1,DRD2,DRD3,DROSHA,DSCAM,DTX3L,DUOXA1,DUOXA2,DUSP10,DVL1,EDN1,EDN2,EDN3,EDNRB,EFNB2,EGFR,EIF2AK2,EIF2AK4,ELMO1,ELMOD2,ENPP4,ENSG00000173366,ENSG00000214732,ENSG00000255439,EPHA4,ESR1,ETS1,F11,F12,F2,F2R,F2RL1,F3,F7,FABP4,FABP7,FAM3A,FAM46A,FANCA,FCER1G,FEM1A,FFAR2,FFAR3,FFAR4,FGF1,FGF10,FGF16,FGF18,FGF2,FGF4,FGFR1,FGG,FKBP1B,FNDC4,FNTA,FNTB,FOXA2,FOXF1,FOXP3,GAS6,GATA3,GBA,GGT1,GHSR,GJA1,GNGT1,GP1BA,GPATCH3,GPER1,GPR17,GPR18,GPR183,GPRC5B,GPSM3,GREM1,GRID2,GRIN1,GRIN3A,GRK4,GRK7,GSTP1,GUCA1B,GUCA1C,GUCY2D,GUCY2F,HAVCR2,HCK,HGF,HMGB1,HMGCR,HPSE,HRG,HSPB1,HTRA1,IDO1,IFIT1,IFNG,IFNLR1,IL10,IL12A,IL12B,IL12RB1,IL15,IL16,IL17A,IL17B,IL17F,IL17RA,IL17RB,IL17RC,IL18,IL1B,IL1R1,IL1R2,IL1RL1,IL1RL2,IL2,IL20,IL20RB,IL21,IL22RA2,IL23A,IL23R,IL27,IL33,IL4,IL6,IL6R,IL6ST,INS,ISL1,ITCH,ITGA2,JAK2,JAM3,KANK2,KARS,KLF4,KLKB1,KLRK1,KNG1,KRT1,LACRT,LBH,LBP,LCK,LDLR,LEP,LGALS9,LPAR1,LPL,LRIG2,LRSAM1,LY86,LY96,LYN,MAPK13,MAPK14,MAPK3,MAS1,MB21D1,MCPH1,MEFV,MEGF8,MET,METAP1,METRNL,MGLL,MGST2,MIF,MKKS,MMP12,MMP26,MMP28,MOSPD2,MPP1,MTOR,MUL1,MYOD1,NBL1,NCKAP1L,NDEL1,NDFIP1,NENF,NFKB1,NLRC3,NLRP1,NLRP10,NLRP6,NLRP7,NLRX1,NMT1,NMT2,NOD1,NOP53,NOS2,NOS3,NOTCH1,NOV,NPFF,NPY,NPY5R,NR1D2,NR1H3,NR1H4,NRP1,NRXN1,NT5E,NTF3,NTRK3,OPRM1,OPTN,OSM,OSMR,OTUD7A,OTULIN,P2RX4,PADI2,PAK2,PARK7,PARP9,PBK,PCBP2,PDE2A,PDE6A,PDE6B,PDGFA,PDGFB,PDGFD,PDGFRB,PDPN,PER1,PF4,PF4V1,PGC,PGLYRP1,PGLYRP2,PHB,PHLDB2,PIK3AP1,PIK3CG,PLA2G2A,PLA2G7,PLAT,PLAU,PLEK,PLG,PLXNA1,PLXNA2,PLXNA3,PLXNA4,PPARA,PPARD,PPARG,PPBP,PPEF1,PPM1F,PPP2R3C,PQBP1,PRDM1,PRKCA,PRKCD,PRKCG,PRKCQ,PRKD1,PRKD2,PRKG1,PROC,PROS1,PROZ,PSMB4,PTEN,PTGER3,PTGER4,PTGIS,PTK2B,PTPRO,PTPRS,PYDC2,RAC1,RAC2,RARRES2,RELA,RGMA,RHBDD3,RICTOR,RIOK3,RIPK2,RIPOR2,RNF125,RNF216,RNF26,ROBO1,ROBO2,RTN4R,S100A12,S100A14,S100A7,S100A8,S100A9,S1PR1,SAA1,SAG,SASH1,SCARA5,SCG2,SCGB1A1,SCRIB,SEC14L1,SELE,SELENOK,SELP,SEMA3A,SEMA5A,SEMA7A,SERPINB2,SERPINC1,SERPINE2,SERPING1,SETD6,SHARPIN,SHPK,SIGIRR,SIRT2,SLC6A3,SLC8B1,SLIT2,SMPDL3B,SNAI2,SNCA,SNW1,SNX4,SOCS3,SOCS5,SOX15,SPAAR,SPINK5,SPN,SPP1,SPX,STAB2,STAP1,STAT1,STK24,STX3,STX4,STXBP5,SUSD4,SYK,SYT11,TAC1,TARBP2,TBC1D23,TBK1,TBXA2R,TC2N,TEC,TEK,TGFB1,TGFBR2,TGM2,THBD,THBS1,THBS4,TIAM1,TICAM1,TIRAP,TKFC,TLR10,TLR2,TLR3,TLR4,TLR6,TLR9,TMEM173,TMPRSS6,TNF,TNFAIP3,TNFAIP6,TNFAIP8L2,TNFRSF11A,TNFRSF1A,TNFRSF1B,TNFSF11,TNFSF14,TNFSF18,TNIP1,TNR,TRAF3,TRAF3IP1,TRAF6,TRIB1,TRIM24,TRIM44,TRIM5,TRIM6,TSPAN32,TSPAN6,TSPAN8,TUBB2B,TXK,TYRO3,UBASH3B,UCN,UFD1,UNC13B,USF1,USP14,USP18,VAMP8,VAV2,VEGFA,VEGFB,VEGFC,VEGFD,VPS33B,VPS35,VTN,WFDC1,WNT3,WNT3A,WNT4,WNT5A,XCL1,XIAP,ZC3H12A,ZNF580,ZP3,ZYX	TetrapodAncestor	258.709
GO.Biological.Process	GO:1902532	negative.regulation.of.intracellular.signal.transduction	69	6.133958e-260	7.923234e-256	1.148295e-257	1.280010e+0	ABL1,ACKR3,ADGRG3,ADIPOQ,ADIPOR1,ADRA1A,AIDA,AJUBA,AKT1S1,AMBP,APLNR,APOE,ARAP3,ARHGAP12,ARHGAP25,ARHGAP35,ARHGAP42,ARHGAP44,ARHGEF2,ARNTL,ARRB1,ARRB2,ASH1L,ASPN,ATF3,ATM,ATP2B4,BANK1,BCL2,BCL2L1,BCL2L10,BCL2L12,BCL2L2,BCL2L2-PABPN1,BCL3,BCL6,BDKRB2,BGN,BID,BMP4,BMP7,C12orf66,C1QBP,C1QL4,C1QTNF3,C3orf33,CALM1,CALM2,CALM3,CAMK2N1,CARD19,CASP8,CASQ2,CASTOR1,CASTOR2,CAV1,CAV3,CAVIN3,CBLC,CCAR2,CCDC125,CCDC22,CD2AP,CD300A,CD44,CD74,CDC34,CDKN2D,CHAD,CHP1,CIB1,CISH,CLU,CNKSR3,CREB3,CREB3L1,CRTC3,CRYBA1,CSK,CUL3,DAB1,DAB2IP,DACT1,DCN,DDIAS,DDIT4,DDX3X,DEPDC5,DEPTOR,DLC1,DLG1,DLG5,DNAJA1,DRD2,DRD3,DUSP1,DUSP10,DUSP16,DUSP18,DUSP19,DUSP2,DUSP21,DUSP22,DUSP26,DUSP3,DUSP6,DUSP7,DUSP8,DUSP9,DYRK1A,DYRK3,EFNA1,EIF3A,ELL3,EPHA2,EPHB2,EPM2A,EPO,ERRFI1,ESR1,EZR,F2RL1,FAF1,FBLN1,FBP1,FBXW11,FIGNL1,FKBP1B,FKTN,FLCN,FLRT1,FLRT2,FLRT3,FOXM1,FOXO1,G3BP2,GBA,GGNBP2,GP1BA,GPATCH3,GPD1L,GPER1,GPS1,GRINA,GSK3A,GSTM2,GSTP1,HDAC3,HDAC7,HERPUD1,HGS,HIF1A,HMGCR,HSPB1,HSPH1,HTRA2,HYOU1,IGBP1,IGF1R,IL10,IL1B,IL1RL1,ING2,INPP5K,INS,IRAK3,ITCH,ITFG2,ITGA3,ITGB1,ITPR1,IVNS1ABP,KANK1,KCTD13,KDM1A,KLF4,KPTN,LAX1,LEMD2,LEPROT,LIF,LIMD1,LITAF,LMBRD1,LMO3,LRRC15,LRRC19,LRRC3,LRRC3C,LRRC4,LRRC4C,LRRC66,LRRK2,LRRTM1,LRRTM3,LRRTM4,LRTM1,LRTM2,LYN,MAGI2,MAPK8IP1,MAPKAP1,MAPKAPK5,MARVELD3,MBIP,MDM2,MECOM,MEN1,MET,MFN2,MGRN1,MIF,MMP9,MSTN,MTM1,MUC1,MUL1,MYADM,MYC,NDUFS3,NEUROD1,NF1,NF2,NFKBID,NLRC3,NLRP6,NLRX1,NME5,NOC2L,NOL3,NOP53,NOV,NPRL2,NPRL3,NR1H4,NUP62,OPA1,OPTN,OTUD3,OTUD7A,OTUD7B,P2RX7,PAFAH1B1,PARK7,PARP14,PBK,PDCD6,PER1,PGAP2,PHB,PHLPP1,PHLPP2,PIK3IP1,PIK3R2,PIN1,PINK1,PKD2,PKHD1,PLEK,PLEKHA1,PODN,PODNL1,PPEF2,PPIF,PPP2CB,PPP2R5B,PPP2R5C,PREX1,PRKAA1,PRKAA2,PRKCD,PRKN,PSCA,PSMD10,PTEN,PTPN1,PTPN22,PTPRJ,PTPRR,PTTG1IP,PYCARD,PYDC2,RANBP9,RAPGEF1,RASA1,RASA2,RASA3,RASA4B,RASAL1,RASAL2,RASAL3,RASSF2,RELA,RFFL,RGS14,RGS2,RGS3,RGS4,RIOK3,RIPK1,RIPOR2,RNF125,RNF149,RNF152,RNF34,RPS6KA6,RRM2B,RRN3,RTN4R,RTN4RL2,SCAI,SEC14L1,SERPINB3,SERPINE2,SESN1,SESN2,SESN3,SFRP1,SFRP2,SFRP5,SH3BP1,SH3BP4,SIRT1,SIRT3,SLA2,SLC9A3R1,SLIT2,SMAD4,SMPD1,SNAI1,SNAI2,SOCS1,SOCS2,SOCS3,SOCS4,SOCS5,SOCS6,SOCS7,SOD2,SORL1,SPAAR,SPINK1,SPRED1,SPRED2,SPRY1,SPRY2,SPRY4,SRC,SRI,STAMBP,STAT1,STK38,STMN1,SYNGAP1,SYNJ2BP,SYVN1,SZT2,TAF9,TAF9B,TBC1D10C,TBC1D7,TGFB2,THBS1,THEM4,TIMP2,TIMP3,TKFC,TLE1,TLR4,TMBIM6,TMEM127,TMEM161A,TNFAIP1,TNFAIP3,TNFAIP8L1,TNIP1,TNIP3,TP73,TPT1,TRAP1,TRDN,TRIAP1,TRIB3,TRIM32,TSC2,TSPAN6,TWIST1,UBR1,UBR2,UCHL1,UFD1,USP10,USP47,VNN1,VRK3,WFS1,WNK2,WWC1,WWC2,WWC3,XBP1,XDH,YBX3,ZC3H12A,ZNF385A,ZNF675	TetrapodAncestor	255.101
GO.Biological.Process	GO:0006468	protein.phosphorylation	70	4.091037e-258	5.284392e-254	7.549132e-256	1.189010e+0	AAK1,ABI1,ABI2,ABL1,ABL2,ACVR1B,ACVR2A,ACVR2B,ACVRL1,ADCK1,ADCK2,ADCK5,ADM2,ADORA2B,AGT,AKAP13,AKT2,ALK,ALPK1,ALPK2,AMHR2,ANGPT1,ANKK1,APP,ARAF,ARTN,ATM,ATP13A2,ATP23,ATR,AURKA,AURKB,AURKC,AVP,AXL,BAZ1B,BCKDK,BCL2,BCR,BIRC5,BIRC6,BLK,BMP10,BMP2,BMP4,BMPR1A,BMPR1B,BMPR2,BMX,BRAF,BRAP,BRSK1,BRSK2,BTC,BTK,BTRC,BUB1,C19orf35,CAB39,CALM1,CAMK1,CAMK1D,CAMK1G,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CAMK4,CAMKK1,CAMKK2,CAMKV,CASK,CASR,CCL11,CCL19,CCL2,CCL3,CCL5,CCL8,CCM2,CCNA2,CCNB1,CCND1,CCNE1,CCNH,CCNK,CCNT2,CCR5,CDC25B,CDC42,CDC42BPA,CDC42BPB,CDC42BPG,CDC42EP5,CDK1,CDK10,CDK13,CDK14,CDK15,CDK16,CDK17,CDK18,CDK19,CDK2,CDK20,CDK4,CDK5,CDK5R1,CDK6,CDK7,CDK9,CDKL2,CDKL4,CDKL5,CFL1,CHEK1,CHEK2,CHUK,CIT,CLEC1B,CLK1,CLK2,CLK3,CLK4,CNTRL,CPNE3,CREB1,CRKL,CRY1,CRYAB,CSF1R,CSF2RA,CSF2RB,CSK,CSNK1A1,CSNK1D,CSNK1E,CSNK1G1,CSNK1G2,CSNK1G3,CSNK2A1,CSNK2A2,CSNK2A3,CSNK2B,CTBP1,CTSH,CUL1,CUL3,CUX1,DAB2IP,DAPK1,DAPK2,DAPK3,DAXX,DBNL,DCAF1,DCLK3,DDR1,DDR2,DGKQ,DGUOK,DLG4,DMPK,DOK5,DRD1,DSTYK,DUSP6,DUSP7,DUSP9,DYRK1A,DYRK1B,DYRK2,DYRK3,DYRK4,EEF2K,EFEMP1,EGF,EGFR,EIF2A,EIF2AK2,EIF2AK3,EIF2AK4,ENSG00000230626,ENSG00000258989,ENSG00000268643,ENSG00000272921,ENSG00000282218,ENSG00000282278,ENSG00000283952,EPGN,EPHA1,EPHA10,EPHA2,EPHA3,EPHA4,EPHA5,EPHA6,EPHA7,EPHA8,EPHB1,EPHB2,EPHB3,EPHB4,EPHB6,EPO,ERBB2,ERBB4,ERC1,ERCC2,ERCC3,ERCC6,EREG,ERG,ERLIN2,ERN1,ERN2,FAM20C,FASTK,FASTKD2,FASTKD3,FASTKD5,FBXW11,FER,FES,FGF1,FGF10,FGF13,FGF16,FGF17,FGF18,FGF19,FGF2,FGF20,FGF22,FGF23,FGF3,FGF4,FGF6,FGF7,FGF9,FGFR1,FGFR1OP,FGFR1OP2,FGFR2,FGFR3,FGFR4,FGR,FLT1,FLT4,FPGT-TNNI3K,FRK,FRS2,FRS3,FYB1,GAK,GAS6,GDF2,GDF6,GDNF,GFRA1,GFRA2,GFRA3,GFRA4,GHR,GLYCTK,GMFB,GMFG,GPS1,GRAP,GRAP2,GRB2,GRIN1,GRIN2A,GRIN2B,GRIN2C,GRIN2D,GRK2,GRK3,GRK4,GRK5,GRK6,GRK7,GSK3A,GTF2H1,GTF2H2,GTF2H3,GTF2H4,GUCY2C,GUCY2D,GUCY2F,HACD3,HASPIN,HBEGF,HCK,HGF,HIPK1,HIPK2,HIPK4,HMGA2,HRAS,HSF1,HTR2B,HUNK,HUS1,IGF1,IGF1R,IKBKB,IKBKE,IKBKG,IL12RB1,IL12RB2,IL15,IL17RD,IL18,IL1B,IL2,IL21,IL24,IL2RB,IL2RG,IL31RA,IL3RA,IL5,IL5RA,ILF3,INS,INSRR,IP6K3,IQGAP3,IRAK1,IRAK3,IRAK4,IRS1,IRS2,ITGAV,ITK,ITPKA,ITPKB,JAK2,JAK3,KALRN,KARS,KBTBD7,KCNH1,KCNH2,KCNH3,KCNH5,KCNH8,KITLG,KL,KRAS,KSR1,LAMTOR2,LAMTOR3,LAT,LATS1,LATS2,LCK,LEP,LGALS9,LIF,LIMK1,LIMK2,LIPE,LMTK2,LMTK3,LRRK2,LTK,LYN,MAK,MAML1,MAP2K2,MAP2K3,MAP2K4,MAP2K6,MAP2K7,MAP3K1,MAP3K10,MAP3K11,MAP3K12,MAP3K13,MAP3K14,MAP3K15,MAP3K19,MAP3K2,MAP3K21,MAP3K3,MAP3K4,MAP3K5,MAP3K6,MAP3K7,MAP3K7CL,MAP3K8,MAP3K9,MAP4K1,MAP4K3,MAP4K4,MAPK1,MAPK10,MAPK11,MAPK13,MAPK14,MAPK15,MAPK3,MAPK4,MAPK6,MAPK8,MAPK8IP1,MAPK8IP3,MAPK9,MAPKAPK2,MAPKAPK3,MAPKAPK5,MARK1,MARK2,MARK4,MAST1,MAST2,MAST3,MAST4,MASTL,MATK,MEF2A,MEF2C,MELK,MEN1,MERTK,MET,MEX3B,MINK1,MKNK1,MKNK2,MMD,MMD2,MOK,MOS,MST1R,MTOR,MUL1,MUSK,MYC,MYLK,MYLK2,MYLK3,MYLK4,MYOD1,NCAM1,NEFL,NEK1,NEK10,NEK11,NEK3,NEK4,NEK5,NEK6,NEK7,NEK8,NEK9,NF1,NFKB1,NIM1K,NLK,NME2,NOD1,NPHS1,NPR1,NPR2,NPRL2,NRAS,NRBP1,NRG1,NRG2,NRG4,NRK,NRTN,NTRK1,NTRK2,NTRK3,NUAK1,NUAK2,OBSCN,OOEP,OSM,OSR1,OXTR,P2RX7,PABPN1,PAK1,PAK2,PAK3,PAK4,PAK5,PAN3,PASK,PBK,PDGFA,PDGFB,PDGFRB,PDIK1L,PDK2,PDK3,PDPK1,PEA15,PEAK1,PELI1,PELI2,PELI3,PHKA1,PHKA2,PHKB,PHKG1,PHKG2,PICK1,PIK3C3,PIK3CA,PIK3CD,PIK3CG,PIK3R1,PIM1,PIM2,PIM3,PINK1,PKD1,PKDCC,PKMYT1,PKN1,PLK1,PLK2,PLK3,PLK4,PLK5,PLVAP,PML,PNCK,PPM1D,PPM1L,PPP3CB,PPP4R1,PPP5C,PRAG1,PRDX4,PRKAA1,PRKAA2,PRKAB1,PRKACA,PRKACG,PRKAG2,PRKAG3,PRKAR1B,PRKCA,PRKCB,PRKCD,PRKCE,PRKCG,PRKCH,PRKCI,PRKCQ,PRKCZ,PRKD1,PRKD2,PRKD3,PRKDC,PRKG2,PRKRA,PRKX,PRLR,PRPF4B,PSKH1,PSKH2,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PSPN,PTGER4,PTK2,PTK2B,PTK7,PTPN1,PTPRA,RAC1,RAF1,RANBP9,RAPGEF2,RARA,RASA1,RASA2,RASA3,RASAL1,RASAL2,RASAL3,RASGEF1A,RASGRF1,RASGRF2,RASGRP1,RASGRP4,RASSF2,RELN,RET,RHBDD3,RICTOR,RIOK1,RIOK2,RIOK3,RIPK1,RIPK2,RIPK3,RIPK4,RNASEL,ROCK2,ROR2,ROS1,RPS27A,RPS6KA1,RPS6KA2,RPS6KA3,RPS6KA4,RPS6KA5,RPS6KA6,RPS6KB2,RPS6KC1,SBK1,SBK2,SBK3,SCG2,SCYL1,SCYL2,SCYL3,SETX,SGK1,SGK2,SH2D3A,SH2D3C,SHC1,SHC2,SHC3,SIK1,SIK2,SIK3,SLA,SLA2,SMAD2,SMAD5,SMAD7,SMG1,SNRK,SOS1,SOX9,SPAG9,SPEG,SPRED1,SPTB,SPTBN2,SPTBN5,SQSTM1,SRC,SRPK1,SRPK2,ST3GAL1,STK16,STK17A,STK17B,STK19,STK24,STK26,STK31,STK32A,STK32B,STK32C,STK35,STK36,STK38,STK38L,STK4,STKLD1,STYK1,SYK,SYNGAP1,TAB1,TAB2,TAB3,TAF1,TAF1L,TAOK1,TAOK2,TBK1,TBRG4,TDGF1,TEC,TEK,TESK1,TESK2,TEX14,TGFB1,TGFB2,TGFBR1,TGFBR2,THY1,TIE1,TLK2,TLR2,TLR3,TLR4,TLR9,TMEM189-UBE2V1,TNF,TNFRSF19,TNFSF11,TNIK,TNIP2,TNK2,TNKS,TNNI3K,TOP1,TP53RK,TPR,TRAF6,TRIB1,TRIB3,TRIM24,TRIM28,TRIO,TRPM6,TRPM7,TSSK1B,TSSK2,TSSK3,TTBK2,TTK,TTN,TXK,TYRO3,UBC,UBE2N,UHMK1,ULK2,ULK3,ULK4,USP15,VRK1,VRK2,VRK3,WDR83,WEE2,WNK1,WNK2,WNK3,WNK4,WNT11,WNT5A,WNT7B,YES1,YWHAB,YWHAE,ZAP70,ZFP36,ZFP36L1,ZFP36L2,ZMYM2	TetrapodAncestor	253.277
GO.Biological.Process	GO:0050776	regulation.of.immune.response	71	1.581266e-255	2.042521e-251	2.876791e-253	1.234635e+0	A2M,ABI1,ABL1,ABR,ACTR2,ACTR3,ADA,ADAM8,ADAR,ADCYAP1,ADGRE2,ADORA2B,AGER,ALOX15,AMBP,ANGPT1,ANKRD17,ANXA1,AP1G1,APLF,APOA1,APOA2,APOB,ARG1,ARG2,ARPC1A,ARPC1B,ARPC2,ARPC4,ARPC5,ARRB2,ATAD5,ATG5,BAG6,BAX,BCAR1,BCL10,BCL2,BCL6,BCR,BIRC2,BIRC3,BLK,BPIFB1,BRAF,BST2,BTK,BTRC,C12orf4,C1QA,C1QB,C1QBP,C1QC,C3,C3AR1,C4A,C4B,C4BPA,C4BPB,C5,C6,C7,C8A,C8B,C8G,C9,CACNA1F,CACTIN,CADM1,CALM1,CARD11,CASP8,CAV1,CBFB,CCL19,CCL5,CCR2,CCR7,CD14,CD160,CD180,CD19,CD1D,CD200R1,CD209,CD226,CD24,CD247,CD276,CD28,CD300A,CD300C,CD300E,CD300LB,CD300LD,CD300LF,CD300LG,CD33,CD34,CD36,CD38,CD3D,CD3E,CD3G,CD40,CD46,CD55,CD59,CD74,CD79B,CD80,CD81,CD86,CD8A,CD8B,CD96,CD99,CDC42,CFH,CFHR1,CFHR2,CFHR4,CFHR5,CFI,CFP,CHUK,CLC,CLCF1,CLEC12B,CLEC2B,CLEC2D,CLEC4A,CLEC4C,CLEC4D,CLEC4E,CLEC4G,CLEC6A,CLEC7A,CLU,CMTM3,CNPY3,CNR1,COL1A1,COL1A2,COL2A1,COL3A1,COLEC10,COLEC11,COLEC12,CPB2,CPN1,CPN2,CR1,CR2,CRK,CRTAM,CSK,CTLA4,CTSB,CTSH,CTSL,CUL1,CXADR,CXCL13,CYBA,CYFIP1,CYFIP2,DAB2IP,DCST1,DDX58,DDX60,DENND1B,DHX9,DMBT1,DRD2,DUSP10,DUSP22,DUSP3,EIF2AK4,ELF1,ELF2,ELMO1,ELMO2,ENSG00000173366,EP300,ERAP1,EREG,ESR1,EXOSC3,EXOSC6,EZR,F2,F2RL1,FADD,FAM3A,FAM49B,FBXW11,FCER1G,FCER2,FCGRT,FCN1,FCN2,FCN3,FER,FES,FFAR2,FFAR3,FGG,FGR,FKBP1A,FLOT1,FOS,FOXF1,FOXJ1,FOXP3,FYB1,FYB2,FZD5,GAB2,GATA2,GATA3,GPATCH3,GPLD1,GPR17,GPR32,GPR33,GPRC5B,GRAP2,GRB2,HAVCR2,HCK,HEXIM1,HLX,HMGB1,HMGB2,HMOX1,HMSD,HRAS,HRG,HSP90AB1,HSP90B1,ICAM2,IDO1,IFITM1,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNAR1,IFNAR2,IFNB1,IFNG,IFNGR1,IFNGR2,IFNK,IFNL1,IFNL2,IFNL3,IGLL1,IGLL5,IKBKB,IKBKE,IKBKG,IL10,IL12A,IL12B,IL12RB1,IL13,IL13RA2,IL15,IL18,IL18RAP,IL1B,IL1RL1,IL2,IL20RB,IL21,IL23A,IL23R,IL27,IL27RA,IL33,IL4,IL6,IL6ST,IL7R,INAVA,INPP5D,INS,IRAK1,IRAK3,IRAK4,IRF1,IRF3,IRF4,IRF7,IRGM,ITCH,ITGA4,ITGAM,ITGB1,ITGB2,ITGB7,ITK,JAK2,JAK3,JAML,JUN,KARS,KIR2DL3,KLHL6,KLRB1,KLRC1,KLRD1,KLRF1,KLRK1,KRAS,KRT1,LAIR1,LAIR2,LAT,LAT2,LAX1,LBP,LCK,LCP2,LEP,LGALS3,LGALS9,LGMN,LGR4,LILRA1,LILRA4,LILRB2,LILRB4,LIMK1,LOXL3,LPXN,LRRC14,LRRC70,LY96,LYN,MADCAM1,MALT1,MAP2K4,MAP2K6,MAP2K7,MAP3K1,MAP3K7,MAPK1,MAPK10,MAPK14,MAPK3,MAPK8,MAPK9,MAPKAPK2,MAPKAPK3,MARCO,MASP1,MASP2,MATR3,MB21D1,MBL2,MEF2C,MIF,MLH1,MMP12,MS4A2,MSH2,MSH6,MUC1,MUC12,MUC13,MUC15,MUC20,MUC3A,MUC4,MUC5AC,MUC5B,MUC6,MUCL1,MUL1,MYB,MYO10,MYO1C,MYO1G,NCK1,NCKAP1,NCKAP1L,NCR1,NCR2,NCR3,NCR3LG1,NDFIP1,NECTIN2,NFAM1,NFATC1,NFATC2,NFATC3,NFKB1,NLRC3,NLRC4,NLRC5,NLRP10,NLRP6,NLRX1,NMI,NOD1,NOP53,NPDC1,NPY5R,NR1D1,NR1H2,NR1H3,NR1H4,NR4A3,NRAS,NSD2,OSCAR,OTUD7A,OTULIN,P2RX7,PAG1,PAK1,PAK2,PAK3,PARK7,PARP14,PARP9,PAWR,PAX5,PAXIP1,PDE4B,PDE4D,PDPK1,PELI1,PGC,PGLYRP1,PGLYRP2,PGLYRP3,PGLYRP4,PHB,PHPT1,PIAS1,PIGR,PIK3AP1,PIK3C3,PIK3CA,PIK3CD,PIK3R1,PIK3R2,PIK3R6,PKN1,PLA2G1B,PLA2G6,PLCG1,PLCG2,PLCL2,PLD2,PLEKHA1,PLPP4,PLSCR1,POLR3B,POLR3C,POLR3D,POLR3F,PPARG,PPP2R3C,PPP3CA,PPP3CB,PPP3R1,PQBP1,PRAM1,PRKACA,PRKACG,PRKCB,PRKCD,PRKCE,PRKCH,PRKCQ,PRKCZ,PRKD2,PRKDC,PROS1,PSEN1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PSPC1,PTAFR,PTK2,PTPN1,PTPN11,PTPN22,PTPRJ,PTPRS,PVRIG,PYCARD,RAB29,RAB7B,RAC1,RAC2,RAET1E,RAF1,RAP1A,RAPGEF1,RARA,RASGRP1,RBCK1,RBM14,RC3H1,REG3G,RELA,RELB,RFTN1,RFTN2,RGCC,RIF1,RIOK3,RIPK1,RIPK2,RIPK3,RNASEL,RNF125,RNF135,RNF31,RPS27A,RPS3,RPS6KA3,RPS6KA5,RSAD2,RUNX1,S100A1,S100A14,S100A8,S100A9,SAMHD1,SAMSN1,SARM1,SASH3,SCRIB,SEC14L1,SELL,SEMA7A,SERPINB4,SERPINB9,SERPING1,SFPQ,SH2D1A,SH2D1B,SHB,SHC1,SIGLEC7,SIGLEC9,SIRT1,SKAP2,SLA2,SLAMF6,SLC11A1,SLC25A6,SLC39A10,SMAD7,SMPDL3B,SNAI3,SNX4,SOCS1,SOCS3,SOCS5,SOS1,SPG21,SPINK5,SPN,SPNS2,SPON2,SPPL2A,SPPL2B,SPPL3,SRC,STAP1,STAT1,STAT2,STAT6,STX4,STX7,STXBP1,STXBP2,STYK1,SUMO1,SUSD4,SYK,TAB1,TAB2,TAB3,TBK1,TEC,TESPA1,TFRC,TGFB1,TGFB2,THEMIS,THEMIS2,THOC1,THY1,TICAM1,TICAM2,TIRAP,TKFC,TLR1,TLR10,TLR2,TLR3,TLR4,TLR5,TLR6,TLR9,TMEM173,TMEM189-UBE2V1,TNF,TNFAIP3,TNFRSF13C,TNFRSF14,TNFRSF21,TNFSF13,TNFSF13B,TNFSF18,TNIP1,TNIP2,TNIP3,TRAF2,TRAF3,TRAF6,TRAFD1,TRAT1,TREM1,TREM2,TREML1,TREML2,TREML4,TRIL,TRIM5,TRIM6,TRPM4,TSPAN6,TXK,TYRO3,UBASH3A,UBC,UBE2D1,UBE2D2,UBE2D3,UBE2N,UBQLN1,UFD1,ULBP1,ULBP3,UNC93B1,UNG,USP18,VAMP8,VAV1,VAV2,VAV3,VCAM1,VSIG4,VTN,WASF2,WDFY1,WIPF2,WIPF3,WNT5A,XBP1,XCL1,XIAP,XRCC5,XRCC6,YES1,ZAP70,ZBTB1,ZNF683,ZP3,ZP4	TetrapodAncestor	250.69
GO.Biological.Process	GO:0009894	regulation.of.catabolic.process	72	3.428983e-255	4.429217e-251	6.151691e-253	1.276375e+0	AAAS,AADAC,ABCD2,ABHD5,ACACB,ADAM8,ADAM9,ADGRB1,ADORA1,ADRA2A,ADRB2,AGAP2,AGO2,AIFM1,AKT2,ALAD,AMER1,ANAPC1,ANAPC11,ANAPC16,ANAPC2,ANAPC4,ANAPC5,ANKIB1,APAF1,APC,APOA1,APOA2,APOA4,APOA5,APOC1,APOC3,APOE,ARAF,ARIH1,ARNTL,ASB9,ATM,ATP13A2,ATP2B4,ATPIF1,ATRAID,ATXN3,AURKA,AZIN1,AZIN2,BAG6,BANP,BARD1,BAX,BBS7,BCAP31,BPGM,BRSK2,BSCL2,BTG2,BTRC,C4BPA,C4BPB,CAV1,CAV3,CCAR2,CCDC22,CCNB1,CD81,CDC16,CDC20,CDC23,CDC26,CDC27,CDC42,CDK1,CDK4,CDKN1B,CEBPA,CHEK2,CHFR,CIDEA,CLEC16A,CLU,CNOT1,CNOT8,CNR1,COMMD1,CPT1A,CRTC3,CSNK1A1,CSNK1D,CSNK1E,CSNK2A1,CSNK2A3,CTSC,CUL1,DAB2,DAB2IP,DACT1,DDA1,DDB1,DDIT4,DDRGK1,DERL2,DERL3,DET1,DFFA,DISC1,DTX3L,DVL1,ECD,ECSCR,EDEM1,EDEM2,EFNA1,EGF,EGFR,EGLN1,EGLN2,EIF6,ENDOG,ENSG00000273734,ENTPD5,EPHA4,ESRRB,ETFBKMT,EZR,FABP1,FAF1,FAM83D,FBP1,FBXL5,FBXO22,FBXO5,FBXW7,FGF21,FHIT,FLNA,FMC1,FMN2,FMR1,FOXO1,FURIN,FZR1,GABARAPL2,GAPDHS,GBA,GCK,GCKR,GGA1,GGA3,GIPC1,GJA1,GNA12,GPC3,GPD1,GPLD1,GRIN2A,GRIN2C,GSK3A,GTPBP1,HDAC4,HERPUD1,HGS,HIF1A,HMGB1,HP,HSF1,HSP90AB1,HSPBP1,HTR2A,HTT,IDE,IFNG,IGF1,IL10,IL1B,IL33,INS,IRAK3,IRS1,IRS2,ITCH,ITGB1,KCNE2,KEAP1,KHSRP,LAMP3,LAPTM4B,LATS1,LDLR,LGALS12,LONP2,LONRF1,LONRF2,LONRF3,LRIG2,LRP1,LRRK2,MAD2L1,MAD2L2,MDM2,MDM4,MLXIPL,MSN,MTM1,MTMR2,MTOR,MYLIP,MYOG,N4BP1,NANOS1,NANOS2,NANOS3,NBAS,NDC1,NDFIP1,NEDD4L,NELL1,NKD2,NOP53,NOS2,NRDC,NRG1,NSF,NUB1,NUDT15,NUP107,NUP153,NUP155,NUP160,NUP188,NUP205,NUP214,NUP35,NUP37,NUP43,NUP50,NUP54,NUP58,NUP62,NUP85,NUP88,NUP98,NUPL2,OAZ1,OAZ2,OAZ3,ODC1,OGT,OPHN1,OS9,P2RX7,PACSIN3,PANO1,PARK7,PBK,PDCL3,PFKFB1,PFKFB2,PFKFB3,PGAM1,PGAM2,PGAM4,PHB,PHKG2,PIAS1,PIK3CG,PIN1,PINK1,PKD1,PKP1,PKP3,PLIN5,PLK1,PLK2,PLK3,PML,PNPLA2,PNPT1,POLR2G,POM121,POM121C,PPARA,PPARGC1A,PPP1CB,PPP1R3B,PPP1R3D,PRICKLE1,PRKAA1,PRKAA2,PRKACA,PRKAG2,PRKCD,PRKCE,PRKCG,PRKN,PRR5L,PSEN1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTEN,PTK2,PTK2B,PTPN1,PTPN3,PTTG1IP,RAB7A,RAD23A,RAD23B,RAE1,RANBP2,RAPGEF3,RARRES2,RC3H1,RCHY1,RDX,RELA,RFWD2,RGN,RGP1,RHBDD3,RHBDF1,RIC1,RNF114,RNF125,RNF128,RNF138,RNF139,RNF14,RNF144A,RNF144B,RNF166,RNF180,RNF19B,RNF217,RNF40,RNF41,RPL11,RPL23,RPL5,RPS27A,RPS7,RYBP,SCARB1,SCO1,SDCBP,SEC22B,SECISBP2,SERPINB12,SERPINE2,SESN2,SF3B3,SGSM3,SGTA,SIRT2,SIRT6,SLIRP,SMAD7,SMARCC1,SMURF1,SNCA,SNF8,SNX1,SNX12,SNX9,SOCS4,SOCS5,SORL1,SOX17,SOX9,SPTLC1,SPTLC2,STUB1,STX5,SUFU,SUMO1,SUMO2,SVIP,TAF1,TAF9,THRA,TIGAR,TIMP1,TIMP2,TIMP3,TIMP4,TIPARP,TLK2,TMTC3,TNF,TNFAIP3,TNFRSF1B,TNFSF12,TNRC6B,TNRC6C,TPR,TRIB1,TRIB2,TRIB3,TRIM32,TRIM39,TWIST1,TYSND1,UBAC2,UBC,UBE2C,UBE2D1,UBE2E1,UBE2G2,UBE2J1,UBE2V2,UBE3A,UBQLN1,UBQLN4,UBXN1,UCHL5,UFL1,UPF1,UQCC2,USP13,USP14,USP25,VCP,VIP,VPS11,VPS28,VPS35,WDR91,WNT1,WNT10B,WNT5A,XBP1,YOD1,ZC3H12A,ZC3HAV1,ZFAND2A,ZFP36,ZFP36L1,ZFP36L2	TetrapodAncestor	250.354
GO.Biological.Process	GO:0030855	epithelial.cell.differentiation	73	3.530878e-254	4.560835e-250	6.247719e-252	1.247501e+0	ABCA12,ABL1,ACADVL,ACER1,ACTA2,ACTL8,ACVR2B,ACVRL1,ADAM9,AFDN,AGR2,AKT2,ANXA1,ANXA4,AR,ARHGEF26,ARID4A,ARX,ASCL1,ATOH1,B4GALT1,B9D1,BARX1,BASP1,BCL11B,BDH2,BFSP1,BFSP2,BMP15,BMP2,BMP4,BMP5,BMP6,BMP7,BMPR2,C1GALT1,CAMSAP3,CAPN1,CASP14,CASP3,CASP6,CBFA2T2,CBR1,CCDC78,CCM2,CCNO,CD24,CD34,CDC42,CDH2,CDH3,CDHR2,CDK1,CDK6,CDKN1A,CEBPB,CELA2A,CEP63,CERS3,CES1,CITED1,CLDN1,CLDN3,CLIC5,CNFN,CNN3,COL18A1,CPS1,CPT1A,CREB1,CRYGD,CSTA,CTNNB1,CTSB,CYP1A1,CYP26B1,DAB2,DACT2,DEUP1,DLG5,DLL1,DLX3,DLX5,DMBT1,DMRT1,DNASE1L2,DSC1,DSC2,DSC3,DSG1,DSG2,DSG3,DSG4,DSP,E2F4,E2F7,E2F8,EDF1,EHF,ELF3,ELF5,EMX1,ENG,EPB41L5,EPHA2,ERBB4,ERCC2,ERCC3,EREG,ESR1,EXPH5,EYA1,EZR,F11R,F2RL1,FA2H,FAM20C,FEM1B,FGF10,FGFR1,FGFR2,FLG,FLNB,FN3K,FNDC3A,FOSL2,FOXA1,FOXC2,FOXF1,FOXJ1,FOXN1,FRMD6,FRS2,FURIN,FZD1,FZD2,FZD7,FZR1,GATA3,GATA4,GATA5,GATA6,GDNF,GPAT4,GPR4,GREM1,GRHL2,GRXCR1,GSTA1,GSTA2,GSTK1,GSTM3,HAPLN2,HDAC1,HDAC2,HEG1,HES1,HES5,HEY1,HEY2,HHEX,HIF1A,HNF1B,HNRNPH3,HRH2,HRNR,HSD17B4,HYDIN,ID1,ID2,ID3,IFT74,IHH,IL31RA,INSM1,INTU,IQGAP1,IRF6,ITGA2,IVL,JAG1,JAG2,JUN,JUP,KAZN,KDF1,KDM5B,KDM6B,KLF15,KLF2,KLF4,KLF5,KRT1,KRT10,KRT12,KRT13,KRT14,KRT15,KRT16,KRT17,KRT19,KRT2,KRT20,KRT23,KRT24,KRT25,KRT26,KRT27,KRT28,KRT31,KRT32,KRT33A,KRT33B,KRT34,KRT35,KRT36,KRT37,KRT38,KRT39,KRT40,KRT5,KRT6A,KRT6B,KRT6C,KRT7,KRT71,KRT72,KRT73,KRT74,KRT75,KRT76,KRT77,KRT80,KRT81,KRT82,KRT83,KRT84,KRT85,KRT86,KRT9,KRTAP1-1,KRTAP1-5,KRTAP10-1,KRTAP10-10,KRTAP10-11,KRTAP10-12,KRTAP10-2,KRTAP10-4,KRTAP10-5,KRTAP10-6,KRTAP10-7,KRTAP10-8,KRTAP10-9,KRTAP11-1,KRTAP12-1,KRTAP12-3,KRTAP12-4,KRTAP13-1,KRTAP13-3,KRTAP13-4,KRTAP15-1,KRTAP17-1,KRTAP19-1,KRTAP19-5,KRTAP19-8,KRTAP2-1,KRTAP2-2,KRTAP2-3,KRTAP2-4,KRTAP20-2,KRTAP21-1,KRTAP21-2,KRTAP21-3,KRTAP23-1,KRTAP24-1,KRTAP27-1,KRTAP29-1,KRTAP3-1,KRTAP3-2,KRTAP3-3,KRTAP4-1,KRTAP4-11,KRTAP4-2,KRTAP4-4,KRTAP4-5,KRTAP4-6,KRTAP4-7,KRTAP4-8,KRTAP4-9,KRTAP5-1,KRTAP5-2,KRTAP5-3,KRTAP5-5,KRTAP5-6,KRTAP8-1,KRTAP9-1,KRTAP9-2,KRTAP9-6,KRTAP9-7,LAMA5,LATS1,LBH,LCE1F,LCE2D,LCE3A,LCE3E,LCE5A,LCE6A,LEF1,LELP1,LGALS3,LHFPL5,LIPK,LIPM,LIPN,LOR,LRTOMT,MAF,MAGI2,MARVELD2,MCIDAS,MCOLN3,MEF2C,MEN1,MESP1,MET,MSN,MTSS1,MYADM,MYO1E,MYO9A,NEUROD1,NEUROG3,NF2,NFIB,NKX3-2,NKX6-1,NOTCH1,NOTCH4,NPHS1,NPHS2,NR0B1,NR5A2,NRG1,NRP1,NTRK1,NTRK3,NUMB,NUP210L,ONECUT1,OPHN1,OVOL2,PAFAH1B1,PALLD,PAX2,PAX8,PCNA,PCSK6,PDE2A,PDE4D,PDGFB,PDPK1,PDPN,PDZD7,PELO,PERP,PGK1,PGR,PI3,PIH1D1,PIP5K1A,PITX2,PKP1,PKP2,PKP3,PLK4,PODXL,POF1B,POU4F3,PPARG,PPHLN1,PPL,PPP1R16B,PRDM1,PROM1,PROX1,PRR9,PRSS8,PSAP,PSAPL1,PTCH1,PTCH2,PTER,PTK7,PTN,PTPRO,PTPRS,RAB13,RAB25,RAP1A,RAP1B,RAP2C,RAPGEF1,RAPGEF2,RAPGEF3,RARA,RARB,RARG,RBPJ,RDX,RFX3,RFX6,RHCG,RILPL1,ROS1,RPTN,RXRA,S100A7,S1PR1,SAFB2,SCEL,SCRIB,SCUBE1,SCX,SEC24B,SFN,SH3BP1,SHARPIN,SHROOM3,SIDT2,SIPA1L3,SIX2,SKIL,SLC4A5,SLC4A7,SLC7A11,SLC9A3R1,SLC9A4,SLITRK6,SMAD4,SMO,SOD1,SOX11,SOX17,SOX18,SOX4,SOX8,SOX9,SPINK5,SPINK6,SPINK9,SPRR1A,SPRR1B,SPRR2A,SPRR2D,SPRR2F,SPRR2G,SPRR3,SPRR4,ST14,STC1,STK4,STRC,SYNE4,TAGLN,TAGLN2,TBC1D20,TBX1,TCF15,TCF21,TCHH,TDRD7,TFCP2L1,TGFB1,TGFB1I1,TGM1,TGM3,THRA,THRB,TIGAR,TJP1,TJP2,TMC1,TMEM100,TMEM231,TMEM79,TMOD1,TNMD,TOLLIP,TP63,TPP1,TSG101,TST,TXNIP,TYMS,UPK1B,UPK2,UPK3A,USH1C,USH2A,VEGFA,VEZF1,VHLL,VIL1,VIM,VSIG1,WDR77,WNT1,WNT11,WNT16,WNT4,WNT5A,WNT7A,WNT7B,XBP1,YIPF6,ZNF703	TetrapodAncestor	249.341
GO.Biological.Process	GO:0043410	positive.regulation.of.MAPK.cascade	74	1.219987e-252	1.575857e-248	2.129537e-250	1.254051e+0	ABL1,ACKR3,ADAM8,ADAM9,ADCYAP1,ADORA1,ADORA2B,ADRA1A,ADRA1B,ADRA2A,ADRA2B,ADRA2C,ADRB2,ADRB3,AGER,AJUBA,AKAP13,ALK,ALKAL1,ALOX15,ANGPT1,ANKRD6,APP,AR,ARAF,ARHGAP8,ARL6IP5,ARRB1,ARRB2,ATP6AP1,AVPI1,BANK1,BMP2,BMP4,BMPER,BRAF,C1QTNF1,C1QTNF2,C5,CALCR,CARTPT,CAV2,CAVIN3,CCL1,CCL11,CCL13,CCL14,CCL15,CCL15-CCL14,CCL16,CCL17,CCL18,CCL19,CCL2,CCL21,CCL22,CCL23,CCL3,CCL3L3,CCL4,CCL4L2,CCL5,CCL7,CCL8,CCR1,CCR7,CD24,CD27,CD36,CD40,CD44,CD74,CD81,CDC42,CDH2,CDK1,CDK10,CDON,CFLAR,CHI3L1,CIB1,CRK,CRKL,CSF1R,CSK,CSPG4,CTGF,CTNNB1,CX3CL1,CXCR4,CYSLTR2,DAB2IP,DAXX,DBNL,DDT,DKK1,DNAJC27,DRD2,DRD4,DSTYK,DUSP15,DUSP19,DUSP22,DUSP6,DUSP7,DUSP9,DVL3,EDA2R,EDAR,EDN1,EDN3,EFNA1,EGF,EGFR,EIF2AK2,EPGN,EPHA4,EPHA8,EPO,ERBB2,ERBB4,ERCC6,ERN1,ERN2,ERP29,EZH2,F2R,F2RL1,FAM58A,FBXW7,FFAR4,FGD2,FGF1,FGF10,FGF18,FGF19,FGF2,FGF20,FGF21,FGF23,FGF4,FGF9,FGFR1,FGFR2,FGFR3,FGFR4,FGG,FLT1,FLT4,FRS2,FSHR,FZD10,FZD4,FZD5,FZD7,FZD8,GADD45A,GADD45B,GADD45G,GAREM1,GAS6,GCNT2,GDF6,GH1,GHR,GLIPR2,GNG3,GPER1,GPNMB,GPR183,GPR37,GPR37L1,GPR55,GRM4,HACD3,HAND2,HAVCR2,HCRTR1,HGF,HIPK2,HMGB1,HMGCR,HRAS,HTR2A,HTR2B,HTR2C,IAPP,IGF1,IGF2,IGFBP4,IKBKG,IL1B,IL26,IL6,INAVA,INS,IQGAP1,IQGAP3,IRAK1,ITGA1,ITGAV,JAK2,JCAD,JUN,KARS,KISS1,KITLG,KL,KRAS,KSR1,LAMTOR2,LAMTOR3,LEP,LGALS9,LIF,LPAR1,LPAR3,LRRK2,LTBR,MADD,MAP2K2,MAP2K3,MAP2K4,MAP2K6,MAP2K7,MAP3K1,MAP3K10,MAP3K11,MAP3K12,MAP3K13,MAP3K14,MAP3K15,MAP3K2,MAP3K21,MAP3K3,MAP3K4,MAP3K5,MAP3K6,MAP3K7,MAP3K7CL,MAP3K8,MAP3K9,MAP4K1,MAP4K3,MAP4K4,MAPK1,MAPK10,MAPK11,MAPK14,MAPK3,MAPK8IP1,MAPK8IP3,MAPKAPK2,MAPKAPK3,MAPKAPK5,MARCO,MID1,MIF,MINK1,MOS,MST1R,MUC20,MUL1,MYDGF,NCF1,NDRG4,NDST1,NECAB2,NEK10,NENF,NGF,NOD1,NOTCH1,NOTCH2,NOX4,NPTN,NPY5R,NQO2,NRG1,NRK,NRP1,NTF3,NTRK1,NTRK2,NTRK3,OPRK1,OPRM1,OSM,P2RX7,P2RY1,PAK1,PAK3,PDCD10,PDE5A,PDE6H,PDE8A,PDGFA,PDGFB,PDGFC,PDGFD,PDGFRB,PEA15,PELI2,PHB,PIK3CG,PIK3R5,PIK3R6,PKN1,PLA2G1B,PLA2G2A,PLA2G5,PLCB1,PLCE1,PLCG1,PRKAA1,PRKCA,PRKCE,PRKCZ,PRKD2,PRMT1,PROK1,PROK2,PSAP,PSEN1,PTEN,PTK2B,PTPN1,PTPN11,PTPN22,PYCARD,RAF1,RAP1A,RAP1B,RAPGEF1,RAPGEF2,RASGRP1,RASSF2,RB1CC1,RIPK1,RIPK2,RIT2,ROBO1,ROR2,RPS27A,RPS3,RYK,S100A12,S100A7,SAA1,SASH1,SDCBP,SEMA4C,SEMA7A,SHC1,SHC2,SLC30A10,SOD1,SORBS3,SOX2,SPAG9,SPRY2,SRC,SSTR4,STK24,STK26,SYK,TAB1,TAB2,TAB3,TAOK1,TAOK2,TBX1,TDGF1,TEK,TENM1,TGFB1,TGFB2,TGFBR1,THBS1,THPO,TIAM1,TIMP2,TIRAP,TLR3,TLR4,TLR6,TLR9,TMEM189-UBE2V1,TNF,TNFAIP8L3,TNFRSF11A,TNFRSF19,TNFSF11,TNIK,TP73,TPD52L1,TRAF2,TRAF4,TRAF6,TRAF7,TREM2,TRIM5,UBC,UBE2N,UNC5CL,VANGL2,VEGFA,WNT16,WNT5A,WNT7A,WNT7B,WWC1,XCL1,XCL2,XDH,ZC3H12A,ZNF622	TetrapodAncestor	247.802
GO.Biological.Process	GO:1903039	positive.regulation.of.leukocyte.cell-cell.adhesion	75	7.576072e-249	9.786012e-245	1.304802e-246	1.428357e+0	ADA,ADAM8,AGER,AIF1,ANXA1,AP3D1,BAD,BCL10,BCL6,BTLA,CARD11,CAV1,CCDC88B,CCL19,CCL2,CCL21,CCL5,CCR2,CD1D,CD209,CD24,CD247,CD27,CD274,CD276,CD28,CD3D,CD3E,CD3G,CD44,CD46,CD47,CD5,CD55,CD59,CD6,CD74,CD80,CD83,CD86,CDC42,CLECL1,CORO1A,CSK,CTLA4,DHPS,DNAJA3,DOCK8,DUSP10,EBI3,EFNB1,EFNB2,EFNB3,EPO,ETS1,FADD,FAM49B,FLOT2,FOXP3,GATA3,GLI2,GLI3,GPAM,GRAP2,GRB2,HAS2,HAVCR2,HES1,HHLA2,HLX,HMGB1,HSPH1,ICOS,IFNG,IGF1,IGF2,IGFBP2,IHH,IL12A,IL12B,IL12RB1,IL15,IL18,IL1B,IL1RL2,IL2,IL21,IL23A,IL23R,IL36B,IL4,IL6,IL6ST,IL7,IL7R,ITGA4,ITPKB,JAK3,KIRREL1,KLRK1,LCK,LEP,LGALS1,LGALS9,LILRB2,LILRB4,LYN,MALT1,MAP3K14,MAP3K7,MAP3K8,MYB,NCK1,NCK2,NCKAP1L,NPHS1,NR4A3,PAK1,PAK2,PAK3,PDCD1,PDCD1LG2,PDPK1,PIK3CA,PIK3R1,PIK3R6,PNP,PRKCQ,PRKCZ,PTAFR,PTPN11,PYCARD,RAC1,RAG1,RARA,RASAL3,RASGRP1,RIPK2,RPS3,SART1,SASH3,SELENOK,SHB,SIRPG,SOCS1,SOCS5,SPN,SRC,SYK,TESPA1,TFRC,TGFB1,TGFBR2,THY1,TMIGD2,TNF,TNFRSF13C,TNFRSF14,TNFSF11,TNFSF13B,TNFSF14,TNFSF9,TRAF2,TRAF6,VAV1,VCAM1,VNN1,VTCN1,XBP1,XCL1,YES1,ZAP70,ZBTB1,ZBTB16,ZMIZ1,ZP3,ZP4	TetrapodAncestor	244.009
GO.Biological.Process	GO:0071363	cellular.response.to.growth.factor.stimulus	76	2.485184e-242	3.210112e-238	4.223832e-240	1.247057e+0	ACAP2,ACVR2A,ACVR2B,ACVRL1,ADAM9,ADAMTS12,ADAMTS7,AKT1S1,AMH,AMHR2,ANGPT2,ANKRD1,ANOS1,APAF1,APP,ARG1,ARRB2,BAG4,BAMBI,BCAR1,BECN1,BGLAP,BMP10,BMP15,BMP2,BMP4,BMP5,BMP6,BMP7,BMP8A,BMP8B,BMPR1A,BMPR1B,BMPR2,BRAF,CASP3,CASR,CAT,CAV1,CBL,CCL2,CCL5,CCNA2,CD44,CDC5L,CDH5,CEP57,CER1,CFLAR,CGN,CHRD,CHRDL1,CIB1,CITED1,CLDN1,CLDN5,CLEC3B,COL1A1,COL1A2,COL2A1,COL3A1,CORO1A,CORO1B,CPNE3,CPS1,CREB1,CRK,CSNK1D,CSNK1E,CTGF,CTNNB1,CX3CR1,CXCL13,CXCL8,DAB2IP,DDC,DDIT4,DDX5,DLL4,DLX5,DSG4,DSTYK,DUSP15,DUSP22,DYNC1LI2,E2F1,EDN1,EEF1A1,EEF2,EEF2K,EGFR,EGR1,EGR3,EHD1,EHD4,EID2,EIF4A3,ENG,EPB41L5,ERBB2,ERBB4,ERN1,ERRFI1,ESRP1,ESRP2,F11R,FAM83G,FAT4,FERMT2,FEZ1,FGF1,FGF10,FGF12,FGF16,FGF17,FGF18,FGF19,FGF2,FGF20,FGF21,FGF22,FGF23,FGF3,FGF4,FGF6,FGF7,FGF9,FGFBP1,FGFR1,FGFR2,FGFR3,FGFR4,FGFRL1,FIBP,FKBP1A,FLRT1,FLRT2,FLRT3,FLT1,FLT4,FMOD,FNTA,FOS,FOXC1,FOXH1,FRS2,FRS3,FSHB,FSTL1,FURIN,FUT8,GAB1,GAREM1,GAS1,GAS6,GATA3,GATA5,GATA6,GCLM,GCNT2,GDF1,GDF10,GDF2,GDF5,GDF6,GRB2,GREM2,GSTP1,GTF2F1,GTF2F2,HAP1,HAS2,HDAC2,HEYL,HFE2,HGF,HIPK2,HNRNPH1,HNRNPM,HPGD,HSPA5,HSPB1,HTR3A,HTRA2,IBSP,ID1,IL10,IL6,INHA,INPP5K,IQGAP1,ITGB5,JUN,KDM5B,KIF16B,KL,KLF10,KLF4,LEF1,LEFTY1,LEFTY2,LHX1,LRP4,LRP8,LTBP4,MAGI2,MAP3K7,MAPK1,MAPK14,MAPK3,MAPKAPK2,MCM7,MDM2,MEF2C,MEGF8,MICALL1,MSTN,MSX1,MSX2,MTMR4,MTSS1L,MYO1C,MYOG,NCBP1,NCBP2,NCL,NDST1,NEDD8,NGF,NGFR,NKX2-5,NLK,NOG,NOS1,NOTCH1,NOX4,NR3C1,NR4A1,NRP1,NRP2,NTRK1,NTRK2,NTRK3,OPRD1,PARD3,PARD6A,PARP1,PAX2,PAX9,PDCD5,PDE2A,PDE3A,PDE8A,PDGFB,PDGFD,PDGFRB,PDPK1,PENK,PFN1,PHOX2B,PLCG1,PLK5,PML,POLR2A,POLR2B,POLR2C,POLR2D,POLR2F,POLR2G,POLR2H,POLR2I,POLR2J,POLR2L,PPARGC1A,PPP2R5B,PRKCZ,PRKD1,PRKD2,PTEN,PTK2,PTN,PTPN11,PTPN12,PTPRK,PXN,RAB14,RAF1,RAMP2,RAP1A,RAPGEF1,RAPGEF2,RBFOX2,RDX,RELA,RGMA,RGMB,RIPK1,ROR2,RPL8,RPS27A,RUNX2,RYR2,SCX,SETX,SFRP1,SH3GL2,SHC1,SHCBP1,SIRT2,SKI,SKIL,SLC33A1,SMAD2,SMAD4,SMAD5,SMAD7,SMURF1,SMURF2,SNAI2,SNCA,SNRNP70,SOS1,SOSTDC1,SOX5,SOX9,SPINT1,SPRED1,SPRED2,SRC,SRD5A1,STAR,STK16,STMN2,T,TAB1,TAC1,TBX1,TDGF1,TGFB1,TGFB2,TGFBR1,TGFBR2,TGFBRAP1,TGIF1,TH,THBS1,TIA1,TIAL1,TMEM100,TMEM108,TNFRSF1B,TNMD,TRIM71,TRPV1,TWF2,TWIST1,UBC,UBE2D1,UBE2D3,UBE2M,UBE3A,USP15,USP8,USP9X,USP9Y,VCAM1,VEGFA,VIL1,VSTM2A,WNT10A,WNT4,WNT5A,WNT7A,WWOX,XCL1,YES1,ZCCHC12,ZFP36,ZFP36L1,ZFP36L2,ZFYVE16,ZFYVE27,ZNF8,ZPR1,ZYX	TetrapodAncestor	237.493
GO.Biological.Process	GO:0042060	wound.healing	77	1.463838e-241	1.890840e-237	2.455636e-239	1.285225e+0	A2M,ACVRL1,ADAM15,ADAMTS13,ADIPOR2,ADORA2A,ADRA2A,ADRA2B,ADRA2C,AJUBA,AK3,AKAP1,AKAP10,ALOX15,ANO6,ANXA1,ANXA5,APOA5,APOD,APOH,AQP1,ARHGAP35,ARHGEF19,ARRB1,ARRB2,AXL,B4GALT1,BCL9,BIN3,BLOC1S3,BLOC1S4,C1GALT1C1,C1QBP,C4BPB,C6orf89,CAPZA2,CAPZB,CARMIL1,CARMIL2,CASP3,CAV3,CCM2L,CCNB1,CD34,CD36,CD40,CD44,CD59,CD9,CDC42,CDH3,CELSR1,CFLAR,CLEC1B,COL1A1,COL1A2,COL3A1,COL5A1,CORO1B,CPB2,CPQ,CX3CL1,CYR61,DCBLD2,DCN,DDR1,DGKA,DGKB,DGKD,DGKE,DGKG,DGKI,DGKK,DGKQ,DGKZ,DOCK11,DOCK6,DOCK8,DOCK9,DRD5,DSP,DTNBP1,DYSF,EGFR,EHD1,EHD2,EHD3,ELK3,ENPP4,ENSG00000243696,ENSG00000259753,ENTPD2,EPB41L4B,ERBB2,ERBB4,EREG,ETS1,EYS,EZH2,F10,F11,F12,F13A1,F13B,F2,F2R,F2RL1,F2RL3,F3,F5,F7,F8,F9,FBLN1,FCER1G,FERMT3,FGF10,FGF2,FGFR1OP2,FGFR2,FGG,FIBP,FLNA,FN1,FNTB,FUT10,FZD6,FZD7,FZD9,GAP43,GAS6,GATA2,GATA3,GATA4,GATA5,GATA6,GGCX,GLI3,GNA11,GNA12,GNA13,GNA14,GNA15,GNAQ,GNAS,GNG2,GP1BA,GP1BB,GP5,GP6,GP9,GPR4,GRHL3,GSN,H3F3A,HBB,HBD,HBE1,HBEGF,HBG1,HBG2,HDAC1,HDAC2,HIF1A,HIST1H3H,HIST1H3I,HIST1H3J,HIST2H3A,HIST2H3C,HIST2H3D,HMG20B,HMOX1,HNF4A,HPS4,HPS5,HPSE,HRG,HSPB1,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNB1,IFRD1,IGF1,IL1A,IL24,IL6,INS,IRF1,IRF2,ITGA2,ITGA2B,ITGA5,ITGA9,ITPK1,ITPR1,ITPR2,ITPR3,JAK2,JAML,JMJD1C,KDM1A,KLKB1,KNG1,KRT6A,LACRT,LARGE1,LAT,LCK,LCP2,LGR6,LMAN1,LOX,LYN,MACF1,MAFF,MAFG,MAP3K5,MAPK1,MAPK14,MAPK3,MCAM,MERTK,METAP1,MFN2,MIA3,MICAL1,MMP12,MMRN1,MSTN,MSX2,MTOR,MTPN,MUSTN1,MYF6,MYH9,MYL9,MYMK,MYOD1,MYOF,MYOG,NDNF,NF1,NINJ1,NINJ2,NLRP6,NOG,NOTCH1,NOV,NRG1,OPRM1,P2RX2,P2RX3,P2RX4,P2RX5,P2RX6,P2RX7,P2RY1,PABPC4,PAFAH2,PAK1,PAPSS2,PAX7,PDCD10,PDGFA,PDGFC,PDGFD,PDGFRB,PDPK1,PDPN,PF4,PF4V1,PHF21A,PIK3CA,PIK3CD,PIK3CG,PIK3R1,PIK3R5,PIK3R6,PKM,PLAT,PLAU,PLCG2,PLEK,PLET1,PLG,PLSCR1,PPARA,PPARD,PRCP,PRKACA,PRKACG,PRKAR1A,PRKAR1B,PRKAR2B,PRKCA,PRKCB,PRKCD,PRKCE,PRKCG,PRKCH,PRKCQ,PROC,PROCR,PROS1,PROZ,PTK7,PTPN11,PTPN12,RAB27A,RAB5A,RAC1,RAC2,RAD51B,RAD51C,RAF1,RAP2B,RBSN,RCOR1,RHOC,RHOG,S100A8,SAA1,SCARB1,SCRIB,SCUBE1,SDC4,SERPINA1,SERPINA10,SERPINA5,SERPINB2,SERPINC1,SERPIND1,SERPINE2,SERPING1,SH2B1,SH2B2,SH2B3,SLC11A1,SLC7A11,SMAD2,SOX15,SOX2,SPRR3,SRC,SRF,STXBP1,SYK,SYT11,SYT7,TEC,TFF1,TFF2,TFF3,TFPI,TFPI2,TGFB1,TGFB2,TGFBR1,TGFBR2,THBD,TIMP1,TLN1,TM4SF4,TMEFF2,TMEM110-MUSTN1,TNC,TOR1A,TRIM72,TRPC3,TRPC6,TRPC7,TSPAN32,TXK,TYRO3,UBASH3B,VANGL2,VAV1,VAV2,VAV3,VCL,VKORC1,VPS45,VWF,WNT10B,WNT3A,WNT5A,WNT7A,YWHAZ,ZFPM1,ZFPM2	TetrapodAncestor	236.723
GO.Biological.Process	GO:0030162	regulation.of.proteolysis	78	9.050672e-241	1.169075e-236	1.498814e-238	1.241539e+0	A2M,A2ML1,ABTB1,ABTB2,ACER2,ADAM8,ADAM9,ADORA2A,ADRA2A,ADRM1,AGT,AHSG,AIFM1,AKIRIN2,ALAD,AMBP,ANAPC1,ANAPC11,ANAPC16,ANAPC2,ANAPC4,ANAPC5,ANGPTL8,ANKIB1,ANOS1,ANTXR1,APAF1,APLP2,APOE,APP,AQP1,ARAF,ARIH1,ARL6IP1,ARL6IP5,ARRB1,ARRB2,ASPH,ASTL,ATP13A2,ATPIF1,ATR,AURKA,AURKAIP1,AVP,BAD,BAG6,BAK1,BAX,BBS7,BCAP31,BCL10,BCL2L10,BCL2L11,BCL2L12,BCL2L13,BID,BIRC2,BIRC3,BIRC5,BIRC6,BLID,BST2,BTBD11,BTBD2,BTBD3,BTBD6,BTBD9,BTRC,C1QA,C1QB,C1QBP,C1QC,C2CD3,C3,C3AR1,C4A,C4B,C4BPA,C4BPB,C5,C6,C7,C8A,C8B,C8G,C9,CAMK2N1,CARD16,CARD17,CARD18,CASP1,CASP2,CASP3,CASP8,CASP9,CAST,CAV1,CAV3,CCAR2,CCBE1,CCDC22,CCK,CCNB1,CD109,CD19,CD27,CD44,CD46,CD55,CD59,CD81,CDC16,CDC20,CDC23,CDC26,CDC27,CDK1,CDK5,CDKN2D,CEBPA,CFH,CFHR1,CFHR2,CFHR4,CFHR5,CFI,CFP,CHAC1,CHFR,CIDEB,CLEC16A,CLEC3B,CLN3,CLN6,CLN8,CLPX,CLU,CNTN2,COL28A1,COL4A3,COL6A3,COL7A1,COMMD1,CPAMD8,CPB2,CPN1,CPN2,CR1,CR2,CRADD,CRB2,CRIM1,CRYAB,CSNK1A1,CSNK1D,CSNK1E,CSNK2A1,CST6,CST7,CSTA,CSTB,CTGF,CTSC,CTSH,CTSZ,CUL1,CYCS,CYFIP2,CYR61,DAB2,DAB2IP,DAP,DAPK1,DDA1,DDRGK1,DDX3X,DET1,DHCR24,DISC1,DLC1,DNAJB6,DNAJC1,DPEP1,DVL1,ECSCR,EFNA1,EFNA3,EGF,EGLN3,EIF2AK3,ENSG00000177359,ENSG00000214776,EPHA4,EPHA7,EPPIN,EPPIN-WFDC6,F12,F2,F2R,F3,FABP1,FADD,FAM162A,FAS,FASLG,FBLN1,FBXO22,FBXO5,FBXW11,FBXW7,FETUB,FGFR4,FHIT,FIS1,FMR1,FN1,FURIN,FZR1,GABARAPL2,GAPDH,GAS1,GAS6,GBA,GIPC1,GLG1,GNA12,GPC3,GPER1,GPLD1,GRAMD4,GSAP,GSN,HDAC2,HERPUD1,HGF,HIP1,HIP1R,HMGB1,HMSD,HPN,HRG,HSF1,HSP90AB1,HSPBP1,HTRA2,IDE,IFI27,IFI6,IFNG,IFT52,IFT57,IGBP1,IL10,IL1B,IL1R2,IL33,IL6,INPP5B,INS,IST1,ITCH,ITIH1,ITIH3,ITIH4,ITIH6,JAK2,KARS,KBTBD4,KCNE2,KEAP1,KIAA0141,KLF4,KLKB1,KNG1,LAMP3,LATS1,LCK,LCN1,LDLRAD3,LEF1,LGALS9,LONRF1,LONRF2,LONRF3,LPA,LRIG2,LRRK2,LTBP4,LXN,LYN,MAD2L1,MAP3K5,MAPK14,MAPK3,MAPT,MDM2,MEFV,MELTF,MICAL1,MMP14,MMP9,MTCH1,MTM1,MUL1,MYC,MYH9,N4BP1,NAIP,NEK5,NGF,NGFR,NKD2,NKX3-1,NLE1,NLRC4,NLRP1,NLRP2,NLRP7,NOD1,NOL3,NOP53,NR1H2,NRDC,NUB1,NUDT15,OGT,OPHN1,PACSIN3,PAK2,PANO1,PAPLN,PARK7,PARL,PAX2,PBK,PCID2,PCSK1N,PDCD2,PDCD5,PDCD6,PDCL3,PERP,PHB,PI15,PI16,PI3,PIAS1,PICALM,PIDD1,PIH1D1,PINK1,PKD1,PLAT,PLGRKT,PLK1,PLK2,PLK3,PMAIP1,PML,POR,PPARG,PPM1F,PRDX3,PRDX5,PRELID1,PRICKLE1,PRKACA,PRKCG,PRKN,PROS1,PSEN1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTEN,PTK2,PTK2B,PTPN3,PTTG1,PTTG2,PYCARD,PZP,R3HDML,RAD23A,RAD23B,RAF1,RAG1,RCHY1,RECK,RENBP,REST,RFFL,RFWD2,RGN,RHBDD1,RHBDF1,RIPK1,RIPK2,RNF114,RNF125,RNF138,RNF139,RNF14,RNF144A,RNF144B,RNF166,RNF180,RNF19B,RNF217,RNF34,RNF40,ROBO1,RPL11,RPL23,RPL5,RPS27A,RPS27L,RPS3,RPS6KA1,RPS6KA3,RPS7,RYBP,S100A8,S100A9,SCO1,SDCBP,SEMG1,SEMG2,SERPINA1,SERPINA10,SERPINA11,SERPINA12,SERPINA3,SERPINA4,SERPINA5,SERPINA6,SERPINA7,SERPINA9,SERPINB1,SERPINB10,SERPINB11,SERPINB12,SERPINB13,SERPINB2,SERPINB3,SERPINB4,SERPINB5,SERPINB6,SERPINB7,SERPINB8,SERPINB9,SERPINC1,SERPIND1,SERPINE2,SERPINE3,SERPING1,SERPINH1,SERPINI1,SERPINI2,SFN,SFRP2,SGTA,SH3RF1,SIAH2,SIRT1,SIRT2,SIRT4,SLPI,SMAD7,SMARCC1,SMURF1,SNCA,SNX12,SNX9,SOCS4,SOCS5,SORL1,SOX2,SOX7,SPINK1,SPINK13,SPINK14,SPINK4,SPINK5,SPINK6,SPINK7,SPINK9,SPINT1,SPINT3,SPINT4,SPOCK1,SPOCK2,SPOCK3,SPOP,SPOPL,SPP2,SRC,SSPO,ST18,STUB1,SUFU,SUMO1,SUMO2,SUSD4,SVIP,TAF1,TAF9,TBC1D10A,TFAP2B,TFPI,TFPI2,THBS1,TIMP1,TIMP2,TIMP3,TIMP4,TLK2,TMEM59,TMTC3,TNF,TNFAIP8,TNFRSF10A,TNFRSF10B,TNFRSF10C,TNFRSF10D,TNFRSF1B,TNFSF10,TNFSF14,TNFSF15,TNIP1,TNP1,TNP2,TP63,TRADD,TRAF2,TRAF3,TRIAP1,TRIB1,TRIB2,TRIB3,TRIM21,TRIM32,TRIM39,UBC,UBE2C,UBE2D1,UBE2E1,UBE2V2,UBE3A,UBQLN1,UBQLN4,UBXN1,UCHL5,UFL1,UMODL1,USP14,USP47,VCP,VEGFA,VIL1,VTN,WDR35,WFDC1,WFDC10A,WFDC12,WFDC13,WFDC2,WFDC3,WFDC5,WFDC6,WFDC8,WFIKKN1,WNT1,WNT10B,WNT3A,WNT9A,XBP1,XDH,XIAP,YWHAE,ZC3H12A,ZFAND2A	TetrapodAncestor	235.932
GO.Biological.Process	GO:0009617	response.to.bacterium	79	1.255308e-238	1.621481e-234	2.052508e-236	1.303638e+0	ABCA1,ABCC2,ABCC8,ABL1,ABR,ACP5,ADAM9,ADAMTS13,ADAMTS5,ADGRB1,ADH5,ADH7,AICDA,AKAP8,AKIRIN2,ALAD,ALPL,ANKRD1,ANKRD17,ANXA3,APOB,ARG1,AXL,BCL10,BCL3,BCR,BDKRB1,BPI,BPIFA1,BPIFA2,C10orf99,C4B,CACTIN,CARD16,CARD17,CASP1,CASP3,CASP8,CASP9,CAV1,CCL2,CCL3,CCL5,CCR4,CCR5,CCR7,CD14,CD160,CD180,CD1D,CD24,CD27,CD36,CD40,CD47,CD6,CD80,CD86,CD96,CDC73,CDK19,CDK4,CEBPB,CEBPE,CFP,CHGA,CHIT1,CHUK,CITED1,CLDN1,CLEC4D,CLEC4E,CMPK2,CNR1,CNR2,CPEB1,CPS1,CSF2RB,CSF3,CX3CR1,CXCL1,CXCL10,CXCL11,CXCL13,CXCL16,CXCL2,CXCL3,CXCL5,CXCL6,CXCL8,CXCL9,CYP1A1,CYP1A2,CYP27B1,DAB2IP,DCD,DCN,DEFB110,DEFB112,DEFB113,DEFB115,DEFB124,DEFB131A,DEFB133,DMBT1,DROSHA,DUSP10,EDN1,EDNRB,ENSG00000173366,EPHA2,EPO,EPPIN,EPPIN-WFDC6,ERAP1,F2,F2R,FAS,FASLG,FCER1G,FCN2,FER,FGF10,FGFR2,FGR,FOS,FUCA2,FZD5,GCH1,GHSR,GJA1,GNG12,GNLY,GNRH1,GSDMD,GSTP1,H2BFS,HAMP,HAVCR2,HCK,HDAC2,HDAC5,HIST2H2BE,HMGB2,HNRNPA0,HP,HPGD,HSF1,IDO1,IFNAR1,IFNB1,IFNE,IFNG,IGLL1,IGLL5,IL10,IL10RA,IL12A,IL12B,IL12RB2,IL13,IL18,IL18BP,IL1B,IL22RA1,IL23A,IL23R,IL24,IL27,IL27RA,IL6,IL6R,INAVA,IRAK1,IRAK3,IRF3,IRF8,IRGM,ISG15,JAK2,JCHAIN,JUN,JUNB,KCNJ8,KLRK1,KRT6A,LACRT,LBP,LCN2,LGALS9,LILRB2,LITAF,LOXL1,LPO,LRRC70,LTBR,LY96,LYG2,LYN,LYZ,LYZL1,LYZL2,LYZL4,LYZL6,MALT1,MAOB,MAPK1,MAPK14,MAPK3,MAPK8,MAPKAPK2,MAPKAPK3,MBL2,MEF2C,MGST1,MGST2,MPO,MR1,MRC1,MTDH,NFKB1,NFKB2,NFKBIB,NGFR,NLRC4,NLRP1,NLRP10,NLRP6,NLRP7,NOCT,NOD1,NOS2,NOS3,NOTCH1,NR1D1,NR1H3,NR1H4,NUGGC,OPRK1,OPRM1,OPTN,OTUD5,P2RX7,PABPN1,PAF1,PALM3,PCK1,PCK2,PDE4B,PDE4D,PELI1,PENK,PF4,PF4V1,PGLYRP1,PGLYRP2,PGLYRP3,PGLYRP4,PLA2G1B,PLA2G2A,PLA2G6,PLAA,PLAC8,PLCG2,PLSCR4,PPARD,PPARGC1A,PPBP,PPM1D,PRB3,PRDX3,PRG2,PRKCD,PRKCE,PRPF8,PTAFR,PTGER1,PTGER2,PTGER4,PTGES,PTGFR,PTGIR,PTPN22,PYCARD,RAB14,RAB1A,RAB29,RAG2,RARA,RARRES2,RBPJ,REG3G,RELA,RELT,REN,RIPK2,RNF5,ROMO1,RPL30,RPS6KA3,S100A12,S100A14,S100A7,S100A8,S100A9,SCARB1,SCGB1A1,SELE,SELP,SEMG1,SEMG2,SERPINB9,SHC1,SHPK,SIRT2,SLC11A1,SLPI,SNCA,SPACA1,SPACA3,SPACA4,SPACA7,SPN,SPON2,SRC,SRR,SSC5D,STAB2,STAP1,STAR,SYK,TAC1,TBK1,TBXA2R,TFPI,TGFB1,TH,THBD,TICAM1,TICAM2,TIMP4,TIRAP,TLR1,TLR2,TLR3,TLR4,TLR5,TLR6,TLR9,TNF,TNFAIP3,TNFRSF10A,TNFRSF10B,TNFRSF10C,TNFRSF10D,TNFRSF11A,TNFRSF11B,TNFRSF14,TNFRSF18,TNFRSF1A,TNFRSF1B,TNFRSF21,TNFRSF25,TNFRSF4,TNFRSF8,TNFRSF9,TNFSF8,TNIP1,TNIP2,TNIP3,TRAF6,TREM1,TREM2,TRIB1,TRIM6,TSPO,UGT1A1,UPF1,VCAM1,VIL1,WDR35,WFDC12,WNT5A,XBP1,ZC3H12A,ZFP36	TetrapodAncestor	233.79
GO.Biological.Process	GO:0070848	response.to.growth.factor	80	2.348674e-237	3.033782e-233	3.792228e-235	1.231426e+0	ACAP2,ACVR2A,ACVR2B,ACVRL1,ADAM9,ADAMTS12,ADAMTS7,AKT1S1,AMH,AMHR2,ANGPT2,ANKRD1,ANOS1,ANXA3,APAF1,APP,ARG1,ARRB2,ASCL1,BAG4,BAMBI,BCAR1,BECN1,BGLAP,BMP10,BMP15,BMP2,BMP4,BMP5,BMP6,BMP7,BMP8A,BMP8B,BMPR1A,BMPR1B,BMPR2,BRAF,CASP3,CASR,CAT,CAV1,CBL,CCL2,CCL5,CCNA2,CD44,CDC34,CDC5L,CDH5,CEP57,CER1,CFLAR,CGN,CHRD,CHRDL1,CIB1,CITED1,CLDN1,CLDN5,CLEC3B,COL1A1,COL1A2,COL2A1,COL3A1,CORO1A,CORO1B,CPNE3,CPS1,CREB1,CRK,CSNK1D,CSNK1E,CTGF,CTNNB1,CX3CR1,CXCL13,CXCL8,DAB2IP,DDC,DDIT4,DDX5,DLL4,DLX5,DSG4,DSTYK,DUSP15,DUSP22,DUSP6,DYNC1LI2,E2F1,EDN1,EEF1A1,EEF2,EEF2K,EGFR,EGR1,EGR3,EHD1,EHD4,EID2,EIF4A3,ELK1,ENG,EPB41L5,EPHA2,ERBB2,ERBB4,ERN1,ERRFI1,ESRP1,ESRP2,F11R,FAM83G,FASLG,FAT4,FER,FERMT2,FEZ1,FGF1,FGF10,FGF12,FGF16,FGF17,FGF18,FGF19,FGF2,FGF20,FGF21,FGF22,FGF23,FGF3,FGF4,FGF6,FGF7,FGF9,FGFBP1,FGFR1,FGFR2,FGFR3,FGFR4,FGFRL1,FIBP,FKBP1A,FLRT1,FLRT2,FLRT3,FLT1,FLT4,FMOD,FNDC4,FNTA,FOS,FOXC1,FOXH1,FRS2,FRS3,FSHB,FSTL1,FURIN,FUT8,GAB1,GAREM1,GAS1,GAS6,GATA3,GATA5,GATA6,GCLM,GCNT2,GDF1,GDF10,GDF2,GDF5,GDF6,GRB2,GREM2,GSTP1,GTF2F1,GTF2F2,HAP1,HAS2,HDAC2,HEYL,HFE2,HGF,HIPK2,HNRNPH1,HNRNPM,HPGD,HSPA5,HSPB1,HTR3A,HTRA2,IBSP,ID1,IL10,IL6,INHA,INPP5K,IQGAP1,ITGB5,JUN,KCNC1,KCNC2,KDM5B,KIF16B,KL,KLF10,KLF4,LEF1,LEFTY1,LEFTY2,LHX1,LRP4,LRP8,LTBP4,LUM,MAGI2,MAP3K7,MAPK1,MAPK14,MAPK3,MAPKAPK2,MCM7,MDM2,MEF2C,MEGF8,MEIS2,MEN1,MICALL1,MSTN,MSX1,MSX2,MTMR4,MTSS1L,MXRA5,MYC,MYO1C,MYOG,NCBP1,NCBP2,NCL,NDST1,NEDD8,NGF,NGFR,NKX2-5,NLK,NOG,NOS1,NOTCH1,NOX4,NR3C1,NR4A1,NRP1,NRP2,NTRK1,NTRK2,NTRK3,OPRD1,OPRM1,P2RY1,PARD3,PARD6A,PARP1,PAX2,PAX9,PDCD5,PDE2A,PDE3A,PDE8A,PDGFB,PDGFD,PDGFRB,PDPK1,PENK,PFN1,PHOX2B,PLCG1,PLK5,PML,POLR2A,POLR2B,POLR2C,POLR2D,POLR2F,POLR2G,POLR2H,POLR2I,POLR2J,POLR2L,PPARGC1A,PPP2R5B,PRKCZ,PRKD1,PRKD2,PTEN,PTH,PTK2,PTN,PTPN11,PTPN12,PTPRK,PXN,RAB14,RAF1,RAMP2,RAP1A,RAPGEF1,RAPGEF2,RBFOX2,RDX,RELA,RGMA,RGMB,RIPK1,ROR2,RPL8,RPS27A,RUNX2,RYR2,SCGB1A1,SCX,SETX,SFRP1,SH3GL2,SHC1,SHCBP1,SIRT2,SKI,SKIL,SLC33A1,SMAD2,SMAD4,SMAD5,SMAD7,SMURF1,SMURF2,SNAI2,SNCA,SNRNP70,SOS1,SOSTDC1,SOX2,SOX5,SOX9,SPINT1,SPRED1,SPRED2,SRC,SRD5A1,STAR,STK16,STMN2,T,TAB1,TAC1,TBC1D7,TBX1,TDGF1,TGFB1,TGFB2,TGFBR1,TGFBR2,TGFBRAP1,TGIF1,TH,THBS1,TIA1,TIAL1,TMEM100,TMEM108,TNC,TNFRSF1B,TNMD,TPR,TRIM71,TRPV1,TWF2,TWIST1,UBC,UBE2D1,UBE2D3,UBE2M,UBE3A,USP15,USP8,USP9X,USP9Y,VCAM1,VEGFA,VIL1,VSTM2A,WNT10A,WNT4,WNT5A,WNT7A,WWOX,XCL1,YES1,ZCCHC12,ZFHX3,ZFP36,ZFP36L1,ZFP36L2,ZFYVE16,ZFYVE27,ZNF8,ZPR1,ZYX	TetrapodAncestor	232.518
GO.Biological.Process	GO:0009896	positive.regulation.of.catabolic.process	81	6.076407e-237	7.848895e-233	9.689994e-235	1.341285e+0	AADAC,ABCD2,ABHD5,ADAM8,ADAM9,ADRA2A,ADRB2,AGO2,AKT2,AMER1,ANAPC1,ANAPC11,ANAPC16,ANAPC2,ANAPC4,ANAPC5,ANKIB1,APC,APOA1,APOA2,APOA4,APOA5,APOE,ARIH1,ASB9,ATM,ATPIF1,ATXN3,AURKA,BAG6,BARD1,BAX,BBS7,BCAP31,BTG2,BTRC,C4BPA,C4BPB,CAV1,CAV3,CCDC22,CCNB1,CD81,CDC16,CDC20,CDC23,CDC26,CDC27,CDK1,CDKN1B,CEBPA,CHFR,CLU,CNOT1,CNOT8,CPT1A,CSNK1A1,CSNK1D,CSNK1E,CSNK2A1,CSNK2A3,CTSC,CUL1,DAB2,DAB2IP,DACT1,DDB1,DDRGK1,DET1,DISC1,DTX3L,DVL1,ECSCR,EDEM1,EDEM2,EGF,EGLN2,ENDOG,ENSG00000273734,ENTPD5,ESRRB,EZR,FABP1,FBXL5,FBXO22,FBXO5,FBXW7,FGF21,FMR1,FOXO1,FURIN,FZR1,GAPDHS,GBA,GGA1,GGA3,GJA1,GPC3,GPD1,GPLD1,GSK3A,GTPBP1,HERPUD1,HIF1A,HMGB1,HSF1,HSPBP1,HTR2A,HTT,IDE,IFNG,IGF1,IL1B,IL33,INS,IRS1,IRS2,ITCH,KCNE2,KEAP1,KHSRP,LDLR,LONRF1,LONRF2,LONRF3,LRP1,LRRK2,MAD2L1,MDM2,MLXIPL,MSN,MYLIP,NANOS1,NANOS2,NANOS3,NDFIP1,NEDD4L,NKD2,NOP53,NRDC,NSF,NUB1,OAZ1,OAZ2,OAZ3,P2RX7,PACSIN3,PFKFB1,PFKFB2,PFKFB3,PHKG2,PIAS1,PLIN5,PLK1,PLK2,PLK3,PNPLA2,PNPT1,POLR2G,PPARA,PRICKLE1,PRKAA1,PRKAA2,PRKCD,PRKCE,PRKN,PRR5L,PSEN1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTEN,PTK2,PTK2B,PTPN1,PTTG1IP,RAB7A,RAD23A,RAPGEF3,RC3H1,RCHY1,RDX,RFWD2,RGN,RHBDD3,RNF114,RNF125,RNF128,RNF138,RNF139,RNF14,RNF144A,RNF144B,RNF166,RNF180,RNF19B,RNF217,RNF40,RNF41,RPS27A,SEC22B,SESN2,SGSM3,SGTA,SIRT2,SMAD7,SMURF1,SNCA,SNF8,SNX1,SNX9,SOCS4,SOCS5,SORL1,SOX17,SOX9,SPTLC1,SPTLC2,STUB1,STX5,SUMO1,SUMO2,TAF1,TIPARP,TMTC3,TNF,TNFAIP3,TNFRSF1B,TNFSF12,TNRC6B,TNRC6C,TRIB1,TRIB2,TRIB3,TRIM32,TWIST1,UBC,UBE2C,UBE2D1,UBE2E1,UBE2V2,UBQLN1,UPF1,UQCC2,USP13,VCP,VIP,VPS11,VPS28,VPS35,WNT5A,XBP1,ZC3H12A,ZC3HAV1,ZFAND2A,ZFP36,ZFP36L1,ZFP36L2	TetrapodAncestor	232.105
GO.Biological.Process	GO:1901342	regulation.of.vasculature.development	82	2.790520e-233	3.604515e-229	4.395750e-231	1.342437e+0	ABCC8,ABL1,ACVRL1,ADAMTS9,ADGRA2,ADGRB1,ADGRB2,ADGRB3,ADM2,AGGF1,AGT,AMOT,ANGPT2,ANGPT4,ANGPTL4,ANXA3,APELA,APLNR,APOH,AQP1,BMP4,BMP7,BRCA1,BTG1,C3,C3AR1,C5,C6,CCBE1,CCL11,CCL2,CCR2,CCR3,CD34,CD40,CFLAR,CHI3L1,CIB1,CNMD,COL4A3,CTH,CTNNB1,CTSH,CX3CL1,CX3CR1,CXCL10,CXCL13,CXCL8,CYBB,CYP1B1,CYSLTR2,DAB2IP,DCN,DDAH1,DLL1,DLL4,ECSCR,EFNA1,EFNA3,EFNB2,EGLN1,EGR1,EMP2,ENG,ENPP2,EPHA1,EPHA2,ERAP1,ERBB2,ETS1,F3,FAM129B,FASLG,FGF1,FGF2,FLT1,FOXC1,FOXC2,FOXO4,GAB1,GATA2,GATA4,GATA6,GDF2,GHSR,GPER1,GPNMB,GPR4,GREM1,GTF2I,HDAC5,HDAC7,HDAC9,HEY1,HEY2,HGF,HHEX,HIF1A,HIF1AN,HIPK1,HIPK2,HMGA2,HMGB1,HMOX1,HRG,HSPB1,HSPB6,HSPG2,ID1,IFNG,IL17F,IL1A,IL1B,IL6,ISL1,ITGA5,ITGB2,JCAD,KLF4,KRIT1,KRT1,LEP,LRG1,MEOX2,MMRN2,MTDH,MYDGF,MYOCD,NF1,NGFR,NOS3,NOTCH1,NPR1,NRP1,PDCD10,PDCD6,PDCL3,PDGFB,PDGFD,PF4,PGK1,PIK3R6,PLCG1,PLXND1,PML,PPARG,PPP1R16B,PRKCA,PRKCB,PRKD1,PRKD2,PROK1,PROK2,PTGIS,PTK2B,PTN,PTPRM,RAMP2,RAP1A,RAPGEF2,RAPGEF3,RGCC,RLN2,RNH1,ROCK2,RRAS,RUNX1,SARS,SASH1,SEMA3E,SEMA4A,SEMA5A,SERPINB7,SFRP1,SFRP2,SIRT1,SIRT6,SP100,SPHK1,SPINK5,SPRED1,SRPX2,STARD13,STAT1,STIM1,SYNJ2BP,TBXA2R,TEK,TERT,TGFBR2,THBS1,THBS2,THBS4,TIE1,TMEM100,TMEM2,TMIGD2,TNFAIP3,TNFRSF12A,TNFSF12,TNMD,TSPAN12,TWIST1,UTS2,UTS2R,VASH1,VASH2,VEGFA,VEGFB,VEGFC,VEGFD,WARS,WNT4,WNT5A,XBP1,XDH,ZC3H12A	TetrapodAncestor	228.443
GO.Biological.Process	GO:0001819	positive.regulation.of.cytokine.production	83	6.298636e-232	8.135948e-228	9.802347e-230	1.331062e+0	ABCC8,ABL1,ADAM8,ADCYAP1,ADIPOQ,ADORA2B,ADRA2A,AFAP1L2,AGER,AGPAT1,AGPAT2,AGT,AGTR2,AKIRIN2,ALOX15B,ANXA1,APOA2,ARFGEF2,ARHGEF2,ATF4,ATP6AP2,BCL10,BCL3,BRCA1,C1QTNF3,C3,C3AR1,C5,CADM1,CARD11,CASP1,CASP5,CCBE1,CCDC88B,CCL19,CCL2,CCL3,CCM2L,CCR2,CCR7,CD14,CD2,CD226,CD274,CD276,CD28,CD34,CD36,CD3E,CD40,CD46,CD58,CD6,CD74,CD80,CD83,CD86,CEBPB,CEBPG,CHIA,CHUK,CLEC4E,CLEC6A,CLEC9A,CLU,CRCP,CREB1,CRTAM,CSF1R,CTNNB1,CX3CL1,CYBA,CYBB,CYP1B1,DDT,DDX3X,DDX41,DDX58,DHX9,DRD2,EBI3,EGR1,EIF2AK2,EIF2AK3,EP300,EPX,EREG,F2R,F2RL1,FADD,FAM49B,FCER1G,FCN1,FERMT1,FFAR2,FFAR3,FGR,FLOT1,FLT4,FOXP3,FZD5,GAPDH,GATA3,GATA4,GDF2,GPRC5B,GPSM3,GSDMD,HAVCR2,HDAC2,HEG1,HGF,HHLA2,HIF1A,HMGB1,HMGB2,HMHB1,HMOX1,HPSE,HRAS,HSPB1,HTR2B,IDO1,IFNAR1,IFNG,IFNL1,IL10,IL12A,IL12B,IL12RB1,IL12RB2,IL13,IL15,IL17A,IL17B,IL17F,IL17RA,IL17RB,IL17RC,IL18,IL18R1,IL1A,IL1B,IL1RAP,IL1RL1,IL1RL2,IL2,IL20RB,IL21,IL23A,IL23R,IL26,IL27,IL27RA,IL33,IL36A,IL36B,IL4,IL6,IL6R,IL6ST,IL9,INAVA,INS,IRAK1,IRF1,IRF3,IRF4,IRF7,IRF8,ISL1,JAK2,KARS,KLRK1,LBP,LEP,LGALS9,LILRB2,LPL,LRRFIP1,LTB,LUM,LURAP1,LY96,MALT1,MAP3K7,MAPK11,MAPK13,MAPK14,MAPK3,MAPKAPK2,MB21D1,MCOLN2,MIF,MMP12,MRE11,MYB,NFAM1,NFATC4,NFKB1,NFKB2,NLRP1,NLRP10,NLRP2,NLRP9,NOD1,NR4A3,ORM1,ORM2,P2RX7,PAEP,PANX1,PARK7,PDE4B,PDE4D,PELI1,PF4,PIK3R1,PLCB1,PLCG2,POLR1C,POLR2F,POLR2H,POLR2L,POLR3A,POLR3B,POLR3C,POLR3D,POLR3E,POLR3F,POLR3GL,POLR3K,PQBP1,PRG2,PRG3,PRKCQ,PRKCZ,PRKD2,PRKDC,PTAFR,PTGER4,PTPN22,PYCARD,PYDC1,RAB7B,RARA,RASGRP1,RELA,RGCC,RIOK3,RIPK1,RIPK2,RNF135,RPS3,RSAD2,RUNX1,SAA1,SASH3,SCAMP5,SELENOK,SEMA7A,SERPINB7,SETD2,SLAMF6,SLC11A1,SOD1,SPN,SPON2,SRC,STAT1,STAT6,SULF2,SYK,TBC1D23,TBK1,TGFB1,THBS1,TICAM1,TIGIT,TIRAP,TLR1,TLR2,TLR3,TLR4,TLR5,TLR6,TLR9,TMEM173,TMIGD2,TNF,TNFRSF13C,TNFRSF14,TNFRSF8,TRAF2,TRAF6,TRIM32,TRIM6,TWIST1,TXK,UCN,VTCN1,WNT11,WNT3A,WNT5A,XBP1,XCL1,XRCC5,XRCC6,ZBP1,ZBTB20,ZFPM1,ZNF580,ZP3	TetrapodAncestor	227.09
GO.Biological.Process	GO:0006469	negative.regulation.of.protein.kinase.activity	84	2.676562e-227	3.457315e-223	4.115851e-225	1.363593e+0	ABL1,ADAR,ADARB1,ADIPOQ,ADORA2A,AIDA,AKT1S1,APC,APOE,ASPN,BGN,BMP4,BMP7,C14orf166,CAMK2N1,CAMK2N2,CASP3,CAV1,CAV3,CBL,CBLB,CBLC,CD300A,CDK5RAP1,CDKN1A,CDKN1B,CDKN1C,CDKN2A,CDKN2B,CDKN2C,CDKN2D,CEBPA,CEP85,CHAD,CHMP6,CHORDC1,CHP1,CIB1,CISH,DAB2IP,DBNDD2,DCN,DEPTOR,DNAJA1,DTNBP1,DUS2,DUSP1,DUSP10,DUSP16,DUSP18,DUSP19,DUSP2,DUSP21,DUSP22,DUSP26,DUSP3,DUSP6,DUSP7,DUSP8,DUSP9,DVL1,EPHA1,EPHB2,ERRFI1,FABP4,FAM212A,FAM212B,FBXO7,FGFR1OP,FLRT1,FLRT2,FLRT3,GADD45A,GADD45B,GBA,GGNBP2,GMFB,GMFG,GNAQ,GP1BA,GPRC5A,GPS1,GSKIP,GSTP1,H2AFY,HEXIM1,HEXIM2,HHEX,HMGCR,HSPB1,IBTK,IGF1R,IL1B,IL6,INCA1,INPP5K,IRAK3,KAT2B,LATS1,LATS2,LAX1,LRP5,LRP6,LRRC15,LRRC19,LRRC3,LRRC3C,LRRC4,LRRC4C,LRRC66,LRRTM1,LRRTM3,LRRTM4,LRTM1,LRTM2,LYN,MAPK8IP1,MBIP,MEN1,MLLT1,MVP,MYOCD,NCK1,NF1,NF2,NPM1,NUP62,PAK2,PARK7,PDPK1,PKIA,PKIB,PKIG,PKN1,PLK1,PODN,PODNL1,PPM1E,PPM1F,PPP1R1A,PPP1R1C,PREX1,PRKAG2,PRKAR1A,PRKAR1B,PRKAR2B,PRKCD,PRKRIP1,PSEN1,PTEN,PTPN1,PTPN22,PTPRJ,PYCARD,PYDC1,RB1,RGN,RGS14,RGS2,RGS3,RGS4,RPTOR,RTN4R,RTN4RL2,SERPINB3,SFN,SFRP1,SFRP2,SH3BP5,SHB,SIRT1,SMCR8,SMPD1,SMYD3,SNX6,SOCS1,SOCS2,SOCS3,SOCS4,SOCS5,SOCS6,SOCS7,SORL1,SPRED1,SPRED2,SPRY1,SPRY2,SRCIN1,STK38,TARBP2,TESC,THY1,TNFAIP3,TP73,TRIB1,TRIB2,TRIB3,TSC2,TSG101,UBASH3B,UCHL1,UVSSA,VPS25,WARS,WEE2,WNK1,WWTR1,YWHAG,ZFYVE28,ZNF675	TetrapodAncestor	222.461
GO.Biological.Process	GO:1901698	response.to.nitrogen.compound	85	9.182014e-226	1.186041e-221	1.395342e-223	1.185179e+0	AACS,AANAT,ABAT,ABCB4,ABCC2,ABCC8,ABL1,ACTR2,ADA,ADAMTS13,ADAR,ADCY2,ADCY3,ADCY4,ADCY5,ADCY8,ADGRL3,ADIPOQ,ADORA2A,ADRB2,ADSS,AGER,AGO1,AGO2,AGO3,AGO4,AGRN,AGRP,AGT,AGTR1,AGTR2,AGTRAP,AGXT,AHCYL1,AIF1,AIFM1,AKAP6,AKR1B1,AKT2,ALAD,ALDH3A1,ANXA1,AOC1,AP3S1,APC,APEX1,APLP1,APOBEC1,APP,APPL1,AQP1,AQP8,AREG,ARG1,ARHGEF2,ARID1B,ASCL1,ASNS,ATF4,ATP1A2,ATP2B4,ATP6AP1,ATP6V0A4,ATP6V0B,ATP6V0C,ATP6V0D1,ATP6V0D2,ATP6V0E1,ATP6V0E2,ATP6V1B1,ATP6V1B2,ATP6V1C1,ATP6V1C2,ATP6V1D,ATP6V1E1,ATP6V1E2,ATP6V1G1,ATP6V1G3,ATP6V1H,AVP,AVPR1A,AVPR1B,AVPR2,BAD,BAIAP2L2,BCAR1,BCHE,BCL11A,BCL2,BCL2L1,BIRC2,BMP7,BRAF,BRCA1,BRIP1,BSG,BTG2,C2CD5,CA2,CACNA1A,CACNA1S,CACNA2D1,CACNB1,CACYBP,CAMK2A,CAPN10,CAPN2,CARM1,CASP1,CASP3,CASP4,CASP6,CASQ2,CASR,CASTOR1,CAT,CAV1,CAV2,CAV3,CCKAR,CCL19,CCL2,CCNA2,CCND1,CCR7,CD36,CD40,CDC5L,CDC6,CDH1,CDK1,CDK2,CDK4,CDK5,CDK5R1,CDKN1A,CDKN1B,CDO1,CEBPB,CFL1,CFLAR,CFTR,CHRM1,CHRM2,CHRM3,CHRM4,CHRM5,CHRNA2,CHRNA3,CHRNA5,CHRNA6,CHRNB2,CHRNB3,CHRNB4,CHRND,CHRNE,CHRNG,CHUK,CIB2,CITED1,CNGA3,CNR1,CNR2,COL16A1,COL1A1,COL1A2,COL3A1,COL5A2,COL6A1,COLEC12,CPEB1,CPEB2,CPEB4,CPS1,CREB1,CRHBP,CRHR1,CRHR2,CRK,CRLS1,CRY1,CSH1,CSK,CTGF,CTNNA1,CTNNB1,CYBA,CYBB,CYC1,CYFIP1,DAXX,DBH,DDC,DDX1,DDX11,DDX21,DDX58,DENND4C,DGKQ,DHFR,DHODH,DHX15,DHX9,DIAPH1,DMTN,DNM2,DNMT3A,DNMT3B,DNTT,DPEP1,DRD1,DRD2,DRD3,DRD4,DRD5,DROSHA,DUOX1,DUOX2,DUSP1,EDN1,EEF2,EEF2K,EFTUD2,EGFR,EGLN1,EGR1,EGR2,EIF2B1,EIF2B3,EIF2B4,EIF2B5,EIF4EBP1,EIF6,ENPP1,ENSG00000255439,ENSG00000278139,EPHA4,EPM2AIP1,EREG,ERRFI1,EZH2,EZR,F7,FABP3,FADD,FDX1,FER,FGF21,FIS1,FKBP1A,FLOT1,FMR1,FOS,FOSB,FOSL1,FOXC2,FOXO1,FOXO4,FUNDC1,GAB1,GABPA,GABRB1,GABRB2,GABRB3,GABRG2,GAL,GCGR,GCK,GCLM,GGH,GH1,GH2,GHR,GHRHR,GHSR,GIP,GJA1,GLDC,GLP1R,GLP2R,GLRA1,GLRA2,GLRA3,GLRA4,GLRB,GNA11,GNA15,GNAI1,GNAO1,GNAQ,GNAT3,GNB2,GNG10,GNG11,GNG12,GNG13,GNG2,GNG3,GNG7,GNG8,GNRH1,GNRHR,GOT1,GPD1,GPER1,GPIHBP1,GPLD1,GPR22,GPRC6A,GRB2,GRIN1,GRIN2A,GRK2,GRM5,GSK3A,GSN,GSS,GSTM1,GSTM2,GSTM3,GSTP1,GUCY1B3,HADHA,HCN1,HCN2,HCN3,HCN4,HCRTR1,HCRTR2,HDAC2,HDAC5,HDAC8,HDAC9,HHEX,HLCS,HMGCS1,HMOX1,HNMT,HNRNPA2B1,HNRNPD,HOMER1,HPCA,HPRT1,HSD11B2,HSF1,HSP90AB1,HSP90B1,HSPA5,HTR1B,HTR2A,HTR3A,ID1,IDE,IFIT1,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNB1,IFNE,IFNK,IFNW1,IGF1,IGF1R,IGF2,IGFBP5,IL10,IL13,IL1B,IL6,INAVA,INHBB,INPP5K,INS,INSIG2,IPO5,IQGAP1,IRAK3,IRF3,IRS1,IRS2,IRS4,ITGA2,ITPR2,JAG1,JAK2,JAK3,JUN,JUNB,JUP,KALRN,KAT2B,KAT7,KCNC1,KCNC2,KCNE1,KCNJ11,KCNJ8,KCNK1,KCNQ1,KDM1A,KHK,KL,KLF1,KLF10,KLF11,KLF15,KLF2,KLF3,KLF4,KLF5,KYNU,LAMTOR2,LAMTOR3,LAMTOR4,LARP1,LARS,LDHA,LEP,LIN28A,LIN28B,LPIN1,LRP1,LRP5,LRP6,LRRK2,LYN,LYPD1,MAP1LC3A,MAP3K5,MAPK1,MAPK14,MAPK3,MARC1,MARC2,MAS1,MAX,MB21D1,MBD1,MC4R,MDM2,MEF2C,MEN1,METTL3,MGARP,MGST1,MGST2,MGST3,MMP19,MMP3,MSX1,MTHFR,MTOR,MUL1,NAIP,NCBP1,NDEL1,NDUFS4,NEFL,NEURL1,NFKB1,NGFR,NKX6-1,NLRP1,NME1,NME2,NNMT,NOD1,NOTCH1,NOX4,NPFF,NPFFR2,NPM1,NR1H4,NR4A1,NR4A2,NR4A3,NSMCE3,NTRK1,NTRK2,OGG1,OGT,OPA1,OPRK1,OPRM1,OR56A1,OR56A4,OR5T3,OTC,OXT,OXTR,P2RX2,P2RX3,P2RX4,P2RX5,P2RX6,P2RX7,PAK1,PANX1,PARP1,PAX4,PCK1,PCNA,PDE12,PDE1B,PDE2A,PDE3A,PDE4B,PDE4D,PDGFC,PDGFD,PDK2,PDPK1,PDXP,PEA15,PELI1,PEMT,PENK,PER1,PFKFB1,PHEX,PHIP,PIK3C2A,PIK3C3,PIK3CA,PIK3CG,PIK3R1,PIK3R2,PIK3R3,PKD2,PKLR,PKM,PLA2G1B,PLA2G5,PLCB1,PLN,PMAIP1,PNPT1,POR,PPARA,PPARG,PPARGC1A,PPARGC1B,PPP1R9B,PPP2R2A,PPP3CA,PPP5C,PQBP1,PRKAA1,PRKACA,PRKACG,PRKAR1A,PRKAR1B,PRKAR2B,PRKCD,PRKCE,PRKCG,PRKCI,PRKCZ,PRKDC,PRKN,PRKRA,PRL,PRLH,PRLR,PSEN1,PTAFR,PTEN,PTK2,PTK2B,PTN,PTPN1,PTPN22,PTPRA,PXN,QDPR,QRFPR,RAB13,RAB31,RAB8A,RAD51,RALB,RANBP2,RAP1A,RAP1B,RAPGEF1,RAPGEF2,RAPGEF3,RBBP4,RECQL5,RELA,REN,RETN,RFTN1,RFTN2,RGS10,RGS8,RHOQ,RIOK3,RIPK2,RNF40,RNLS,RPE65,RPL23,RPTOR,RRAGA,RRAGD,RRM2B,RYR1,RYR2,RYR3,SDK1,SELL,SESN2,SESN3,SFRP1,SH2B2,SH3BP4,SHC1,SHMT1,SIRT1,SIRT2,SLC1A2,SLC22A6,SLC25A33,SLC26A3,SLC27A1,SLC2A1,SLC2A8,SLC30A10,SLC34A1,SLC38A9,SLC3A2,SLC5A5,SLC6A3,SLC6A4,SLC7A11,SLC8A1,SLC8A3,SLC9A1,SLIT2,SLURP2,SMAD2,SMARCC1,SMPD1,SNCA,SNIP1,SOCS1,SOCS2,SOCS7,SOD1,SOGA1,SORBS1,SOS1,SOX9,SP1,SPAAR,SPIDR,SPOUT1,SRC,SRD5A1,SRD5A2,SREBF1,SRR,SRRT,SRSF4,SRSF5,SRSF6,SRSF9,SST,STAR,STAT1,STAT6,STC1,STC2,STXBP4,TAC1,TACR3,TAF1,TARBP2,TBC1D4,TCIRG1,TEK,TERT,TFF1,TGFB1,TH,THBD,TIAM1,TICAM1,TIMELESS,TIMP1,TIMP4,TLR2,TLR3,TLR4,TLR6,TMBIM6,TMED10,TMEM173,TNF,TNFAIP3,TNFSF10,TP53,TP73,TRAF2,TRDMT1,TREM2,TRIB3,TRIM71,TRPC3,TRPM2,TRPV1,TSHR,TSN,TSNAX,TSPO,TUSC5,TYMS,TYR,UBE3A,UBR1,UBR2,UCP2,UCP3,UFL1,UMODL1,UPRT,UQCRC1,USF1,VAMP2,VCAM1,WDTC1,WNT1,WNT10B,XBP1,XRN1,YWHAG,ZC3H7A,ZCCHC11,ZEB1,ZFP36L1,ZNF106,ZNF354A	TetrapodAncestor	220.926
GO.Biological.Process	GO:0090287	regulation.of.cellular.response.to.growth.factor.stimulus	86	3.066901e-225	3.961516e-221	4.606414e-223	1.310872e+0	ABL1,ACVR2A,ACVRL1,ADAMTS12,ADAMTS3,ADAMTSL2,ADGRA2,AGT,AGTR2,ASPN,BAMBI,BCL9L,BMP4,BMPER,BMPR2,CASK,CAV1,CAV2,CAV3,CCBE1,CD109,CD63,CDKN1C,CDKN2B,CER1,CFLAR,CHRD,CHRDL1,CHST11,CIDEA,CITED1,CITED2,CRB2,CTDSPL2,CTNNB1,CXCL13,CYFIP1,CYFIP2,CYR61,DAB2,DAB2IP,DAND5,DCN,DKK1,DKK3,DLL1,DNM2,DOK5,DSTYK,DUSP6,EID2,ENG,FAM129B,FAM20C,FAM89B,FBN2,FBXL15,FERMT1,FGF1,FGF10,FGF16,FGF18,FGF2,FGF4,FGF9,FGFBP1,FGFBP3,FGFR1,FGFR2,FLCN,FLT1,FSTL3,FUZ,FZD1,FZD4,GATA3,GATA4,GATA6,GDF2,GDF3,GDF5,GIPC1,GLG1,GPC1,GPC3,GRB10,GREM1,GREM2,HES1,HES5,HFE2,HHEX,HIF1A,HIPK2,HRG,HSP90AB1,HSPA5,HTRA1,HTRA3,HTRA4,IL17F,IL1B,ING2,ITGA3,ITGA5,ITGA8,JCAD,LDLRAD4,LEMD2,LEMD3,LRG1,LRIT3,LTBP4,MEN1,MMRN2,MSX1,MSX2,MTMR4,MYO1C,MYOCD,MYOF,NBL1,NEO1,NOG,NOTCH1,NPTN,ONECUT1,OTX2,PBLD,PCSK6,PDCD6,PDPK1,PELO,PIN1,PMEPA1,PPP2R5B,PRDM16,PRKCB,PRKD2,PTP4A3,PTPN1,RASL11B,RBPJ,RBPMS2,ROBO1,RPS27A,RUNX2,SDCBP,SFRP1,SFRP2,SFRP4,SFRP5,SHISA2,SIRT1,SKI,SKIL,SKOR2,SLIT2,SMAD2,SMAD4,SMAD7,SMURF1,SMURF2,SNW1,SNX6,SOST,SOSTDC1,SOX11,SPRY1,SPRY2,STRAP,STUB1,SULF2,TFAP2B,TGFB1,TGFB1I1,TGFBR1,TGFBR2,THBS1,TMEM108,TMEM204,TMPRSS6,TRIM33,UBC,VEGFA,VEGFC,VTN,VWC2,VWC2L,WFIKKN1,WNT1,WNT4,WNT5A,XDH,XIAP,ZEB1,ZNF423,ZNF703	TetrapodAncestor	220.402
GO.Biological.Process	GO:0051050	positive.regulation.of.transport	87	1.158666e-224	1.496649e-220	1.720286e-222	1.183963e+0	AACS,ABAT,ABCA1,ABCA12,ABCB4,ABCC8,ABCG1,ABL1,ABLIM3,ABR,ACHE,ACSL3,ACSM6,ACTN4,ADAM8,ADAM9,ADCYAP1,ADCYAP1R1,ADIPOQ,ADIPOR2,ADORA1,ADORA2A,ADORA2B,ADRA2A,ADRB2,AGER,AGT,AGTR2,AHCYL1,AHI1,AHSG,AKAP6,AKT2,ALG10B,ALOX15B,ANGPT1,ANK2,ANK3,ANKRD1,ANO1,ANO6,ANXA1,AP1G1,APELA,APLN,APLNR,APOA5,APOE,APP,AQP1,ARC,ARF1,ARHGEF7,ARL6IP1,ARRB1,ARRB2,ATAD1,ATG13,ATG5,ATP13A2,ATP1B1,ATP1B2,ATP1B3,ATP6AP1,ATP8A1,ATP8A2,ATPIF1,AVP,AVPR1A,AXL,AZIN1,AZIN2,B3GAT3,BAD,BAK1,BAMBI,BAP1,BAX,BCAP31,BCAS3,BCL2,BCL2L11,BCR,BDKRB1,BICD1,BID,BLK,BMP4,BMP6,BMPR1A,C1QTNF1,C1QTNF12,C1QTNF2,C1QTNF3,C2CD2L,C2CD5,C3,C4A,C4B,C5,C8orf4,CA2,CACNA1D,CACNA1G,CACNA1H,CACNA1I,CACNA2D1,CACNB2,CADM1,CADPS2,CALCR,CALM1,CALM2,CALM3,CALR,CALY,CAMK1,CAMK1D,CAMK2A,CAPN10,CARTPT,CASK,CASP1,CASP5,CASP8,CASQ1,CASR,CAV1,CAV3,CBL,CBLL1,CCK,CCL19,CCL2,CCL21,CCL3,CCL4,CCL5,CCR1,CD14,CD19,CD2,CD27,CD274,CD300LF,CD34,CD36,CD38,CD47,CD58,CD63,CDC42,CDH1,CDH2,CDH3,CDK1,CDK5,CDK5R1,CDK5R2,CDKL2,CEMIP,CFTR,CHERP,CHIA,CHMP2A,CHP1,CHRM1,CHRNB2,CHUK,CIB1,CLASP1,CLASP2,CLEC4E,CLEC6A,CLEC9A,CLIP3,CLTCL1,CNKSR3,CNST,CNTN1,COX17,CPB2,CRACR2A,CREB1,CREBL2,CRTAM,CSF1R,CSF3,CSNK2A2,CTDSPL2,CXCL10,CXCL11,CXCL9,CYB5R1,CYBA,CYP19A1,CYP4A11,DAB2,DACT1,DDX58,DHX9,DLG1,DLL1,DMAP1,DMD,DNM1,DNM1L,DNM2,DOC2B,DOCK2,DRD1,DRD2,DRD3,DRD4,DTNBP1,DTWD2,DYNC1H1,DYNLL1,DYNLL2,E2F1,ECT2,EDA,EDAR,EDEM1,EDEM2,EDN1,EDN3,EDNRB,EEF2K,EGF,EGFR,EHD1,EHD2,EHD3,ELMOD1,ENSG00000240045,ENSG00000278139,EPHB2,ERBB2,ERBB4,ERFE,EXPH5,EZR,F2,F2R,F2RL1,F2RL3,FAM20B,FBXW7,FCER1G,FCN1,FERMT1,FFAR1,FFAR2,FFAR3,FGF12,FGF14,FGF19,FGF21,FGFR1,FGG,FGR,FIS1,FLNA,FLOT1,FMR1,FXYD1,FZD5,G6PD,GAB2,GAL,GALR2,GAPDH,GAS6,GATA2,GATA3,GCK,GDNF,GHRH,GHRHR,GIP,GIPR,GJA1,GJC2,GLI3,GLRX,GLUD1,GLUL,GOLPH3,GPC3,GPD1L,GPER1,GPHA2,GPLD1,GPR68,GREM1,GRIN1,GRK2,GRM6,GRP,GSDMD,GSK3A,GSTM2,GTSE1,HAP1,HAVCR2,HCLS1,HDAC3,HES1,HGS,HHAT,HIF1A,HIP1,HIP1R,HIST1H1A,HMGB1,HMHB1,HNMT,HNRNPK,HOMER1,HPCA,HPS4,HSP90AB1,HSPA2,HTR2B,HTR3A,HTRA2,HTT,ICE1,IFNAR1,IFNG,IFNL3,IGF1,IL10,IL12B,IL13,IL17A,IL17F,IL17RA,IL17RB,IL17RC,IL18,IL18R1,IL1A,IL1B,IL1RAP,IL1RL1,IL2,IL23A,IL26,IL33,IL4,IL5,IL6,INHA,INHBA,INHBB,INPP5K,INS,IPO5,IRF3,IRS1,IRS2,ISL1,ITGA2,ITGAM,ITGAV,ITGAX,ITGB2,JAK2,JPH2,JUP,KANK1,KARS,KCNA1,KCNB1,KCNC1,KCNC2,KCNE1,KCNE2,KCNE3,KCNE5,KCNH2,KCNJ11,KCNJ2,KCNMB1,KCNN3,KCNQ1,KHDRBS1,KIF20B,KIF5B,KISS1,LACRT,LDLR,LDLRAP1,LEP,LEPROT,LGALS3,LGALS9,LIPG,LMAN2,LPAR3,LPL,LRAT,LRP1,LRRC26,LRRC38,LRRC52,LRRC55,LRRK2,MAGI2,MAP2K6,MAPK1,MAPK11,MAPK14,MAPK3,MAPK8,MBL2,MCU,MDM2,MERTK,MFF,MFGE8,MIB1,MIEF1,MIEF2,MIF,MIS18A,MLC1,MMP12,MPC2,MRGPRE,MSN,MTMR2,MYB,MYBPC1,MYLK,MYO18A,MYO1C,MYRIP,NCBP2,NCKAP1L,NCS1,NEDD4L,NIPSNAP2,NKX2-5,NKX3-1,NKX6-1,NLGN1,NLGN3,NLRP1,NLRP10,NLRP2,NMT1,NMUR1,NNAT,NOS1,NOS1AP,NPEPPS,NPR1,NPSR1,NPY2R,NR0B2,NR1H2,NR1H3,NR1H4,NR4A3,NRG1,NTF3,NTSR1,NUTF2,OAZ1,OAZ2,OPA1,OPRK1,OPRL1,OR51E2,ORM1,ORM2,OXCT1,OXT,OXTR,P2RX2,P2RX3,P2RX4,P2RX5,P2RX7,P2RY1,P2RY2,PAEP,PAK1,PANX1,PARK7,PARP1,PCK2,PCM1,PCNT,PDCD10,PDCD5,PDCD6IP,PDGFB,PDGFRB,PDPK1,PEMT,PFKFB2,PHPT1,PICALM,PICK1,PIK3R1,PIK3R2,PIK3R3,PINK1,PKD2,PKP2,PLA2G10,PLA2G1B,PLA2G6,PLAA,PLCG1,PLCG2,PLK3,PLTP,PMAIP1,POLR3A,PPARD,PPARG,PPP1R13B,PPP3CA,PPP3CB,PPP3CC,PPP3R1,PPT1,PRELID1,PRELID3A,PRKACA,PRKCD,PRKCE,PRKCI,PRKCZ,PRKN,PRR5L,PRSS8,PSEN1,PSMB7,PSMD8,PSMD9,PTAFR,PTCH1,PTGER4,PTH,PTPN11,PTPN22,PTPN23,PTX3,PYCARD,PYDC1,RAB15,RAB21,RAB27A,RAB27B,RAB29,RAB2B,RAB3B,RAB3D,RAB3GAP1,RAB5A,RAB7A,RAB8B,RAC2,RAP1A,RAPGEF1,RAPGEF3,RARRES2,RASGRP1,RASL10B,RBCK1,RBM22,RBP4,RBPMS,RDX,RELN,RETN,RFX6,RGCC,RGN,RHOQ,RHOU,RIOK2,RIPK2,RIPOR1,RNASEL,RNF207,RNF31,RPH3AL,RPL28,RUFY3,RUVBL1,RYR2,S100A1,S100A8,SAA1,SCAMP5,SCIN,SCN1B,SCN3B,SCN4B,SCN5A,SCP2,SCT,SCYL2,SDC4,SDCBP,SEC16B,SELE,SELENOI,SELENOK,SELENOT,SEMA5A,SERP1,SFN,SFRP2,SFRP4,SGIP1,SGK1,SGK2,SH3GLB1,SIRT1,SIRT3,SLC11A1,SLC1A2,SLC30A8,SLC34A1,SLC35D3,SLC51B,SLC6A4,SLC9A1,SMAD4,SMO,SMPD3,SNAPIN,SNCA,SNF8,SNIP1,SNX4,SORBS1,SORL1,SOX11,SOX4,SPACA3,SPHK1,SPP1,SPPL3,SRC,SREBF2,SRI,STAM,STAP1,STARD7,STC1,STIM1,STIM2,STOM,STX18,STX1A,STX1B,STX4,STXBP1,STXBP5,STXBP5L,SULF2,SUMO1,SYBU,SYK,SYNGR3,SYT1,SYT10,SYT4,SYT7,SYT9,SYTL2,SYTL4,TAC1,TAC4,TARDBP,TBC1D20,TBC1D5,TDRD12,TENM1,TERT,TESC,TF,TFDP2,TFR2,TGFB1,TGFB2,TGFBR1,THY1,TLR1,TLR2,TLR3,TLR4,TLR9,TM7SF3,TM9SF4,TMEM110,TMEM173,TMEM27,TMEM30B,TNF,TNFRSF11A,TNFRSF14,TNFRSF4,TNFSF11,TNFSF14,TOMM7,TOR1A,TP53,TP53BP2,TP63,TP73,TPR,TRDN,TRIAP1,TRIM28,TRIM6,TRIP6,TRPC1,TRPC3,TRPC6,TRPM4,TRPV1,TRPV3,TSG101,TSGA13,TSPO,TTN,TUB,TULP1,TWIST1,U2AF1,U2AF2,UBE2D3,UBE2J2,UBE2L3,UBL5,UBR5,UCN,UCN3,UGCG,UNC13A,UNC13B,USP36,VAMP2,VAMP8,VEGFA,VEGFC,VPS11,VPS28,VPS35,VPS37B,VPS4A,VPS4B,VSNL1,VTCN1,VTN,WBP11,WDR46,WDR75,WFS1,WLS,WNK2,WNK3,WNT3A,WNT5A,XBP1,XCL1,XPO4,YWHAB,YWHAE,YWHAG,YWHAH,YWHAZ,ZBED3,ZBTB17,ZC3H12A,ZDHHC8,ZIC1,ZNF205,ZP3,ZPR1	TetrapodAncestor	219.825
GO.Biological.Process	GO:0080135	regulation.of.cellular.response.to.stress	88	2.038406e-223	2.633009e-219	2.992056e-221	1.221165e+0	AAAS,ABL1,ACKR3,AGER,AGR2,AIDA,AJUBA,AKT1S1,AMBP,ANKLE1,ANKRD1,ANKRD6,APP,ARG2,ARHGEF2,ARL6IP5,ARNTL,ATF4,ATM,ATPIF1,ATR,ATXN3,AXIN2,BABAM1,BABAM2,BAD,BAG1,BAG2,BAG4,BAG6,BAK1,BAX,BCAP31,BCL2L1,BCL2L11,BCL2L12,BCL6,BCLAF1,BDKRB2,BFAR,BID,BMP2,BMP7,BMPR1A,BRAF,BRCA1,BRCC3,BRSK2,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CASP9,CAV1,CAV3,CBX8,CCAR2,CCL19,CCL21,CCR7,CD27,CD34,CD36,CD44,CD74,CDC42,CDK6,CDK9,CDKN2A,CDKN2D,CEBPG,CERS2,CHCHD2,CHEK1,CHEK2,CHORDC1,CLU,CNTF,CREB3,CREB3L1,CRY1,CRYAB,CTGF,CTNNB1,CUL4A,CXorf57,DAB2IP,DACT1,DAXX,DBNL,DDAH1,DDIAS,DDX11,DDX5,DEK,DERL2,DERL3,DHFR,DHX9,DKK1,DLG1,DNAJA1,DNAJB1,DNAJB6,DNAJC2,DTNBP1,DTX3L,DUSP10,DUSP15,DUSP19,DUSP22,DUSP3,DVL3,DYRK1A,DYRK3,EDA2R,EDAR,EDEM1,EDEM2,EDN1,EGFR,EIF2AK2,EIF2AK3,EIF2AK4,ELL3,ENDOG,EP300,EPHA4,EPHB1,EPO,ERCC1,ERCC4,ERCC6,ERN1,ERN2,ERP29,ETAA1,EYA1,EYA2,EYA3,EYA4,EZR,F2RL1,FAM168A,FAS,FBLN5,FBXO18,FBXO4,FBXO7,FBXW7,FEM1B,FGD2,FGF10,FGF19,FIGNL1,FIGNL2,FKBP1B,FKBP4,FKTN,FLT4,FMR1,FOXM1,FOXO1,FUT8,FZD1,FZD10,FZD4,FZD5,FZD7,FZD8,GADD45A,GADD45B,GADD45G,GBA,GCH1,GDF6,GPR37,GPR37L1,GRIK2,GRINA,GSTP1,H2AFX,HACD3,HAND2,HDAC3,HELB,HERPUD1,HGF,HIC1,HIF1A,HIKESHI,HIPK2,HMGA2,HMGB1,HMGCR,HNRNPK,HRAS,HSBP1,HSF1,HSP90AB1,HSPA5,HSPA8,HSPB1,HSPB8,HSPH1,HTRA2,HYOU1,IER3,IER5,IGBP1,IGF1R,IL1B,IL26,INAVA,ING2,INS,ITCH,KARS,KCNK2,KDM1A,KDM4D,KLF4,KLHL15,KRAS,LEP,LRIG2,LRRK2,LTBR,LYN,MAGI3,MAP2K2,MAP2K4,MAP2K7,MAP3K10,MAP3K11,MAP3K2,MAP3K21,MAP3K3,MAP3K4,MAP3K5,MAP3K6,MAP3K7,MAP3K9,MAP4K1,MAP4K4,MAPK1,MAPK3,MAPK8IP1,MAPK8IP3,MAPKAPK2,MAPT,MARVELD3,MB21D1,MBIP,MDM2,MECOM,MEN1,MET,MID1,MIF,MINK1,MLST8,MMP3,MRNIP,MSX1,MTOR,MUC1,MUL1,MYC,NBR1,NCF1,NCK1,NCK2,NCOA7,NDC1,NDEL1,NEK4,NEK6,NKX3-1,NME5,NOD1,NOL3,NPAS2,NPM1,NR4A3,NRK,NSD2,NSMCE1,NSMCE4A,NTRK3,NUAK1,NUDT16,NUDT16L1,NUP107,NUP153,NUP155,NUP160,NUP188,NUP205,NUP214,NUP35,NUP37,NUP43,NUP50,NUP54,NUP58,NUP62,NUP85,NUP88,NUP98,NUPL2,OGG1,OPA1,OPRK1,OS9,OTUB1,OXR1,P4HB,PAFAH1B1,PAK1,PARK7,PARP1,PARP9,PARPBP,PAWR,PAXIP1,PBK,PCNA,PDCD10,PDE8A,PDILT,PER1,PGAP2,PHLPP1,PIAS4,PIK3R1,PINK1,PKN1,PLCB1,PMAIP1,PML,PNPT1,POLH,POLQ,POM121,POM121C,PPEF2,PPP1R15A,PPP1R15B,PPP4C,PPP4R2,PRDX1,PRKCD,PRKCG,PRKDC,PRKN,PRMT1,PRRX1,PSAP,PSMD10,PTEN,PTK2B,PTPN1,PTPN22,PTPRS,PTTG1IP,PYCARD,PYCR1,RAD51,RAD51AP1,RAD52,RAD9A,RAE1,RANBP2,RAP2A,RAPGEF1,RASGRP1,RASSF2,RB1CC1,RECQL5,RFWD3,RGMA,RGN,RIF1,RINT1,RIPK1,RIPK2,RNASEH2B,RNF168,RNF169,RNF8,ROR2,RPA2,RPA3,RPS3,RPTOR,RSL1D1,RTN4R,RWDD3,SASH1,SDCBP,SEMA4C,SERINC3,SERPINB3,SETD2,SETMAR,SFPQ,SFRP1,SFRP2,SGTA,SH3RF1,SIRT1,SIRT6,SKIL,SLC30A10,SLF1,SLF2,SMYD2,SNAI1,SNAI2,SOD1,SOD2,SPAG9,SPIDR,SPOP,SPP1,SPRED1,SPRED2,STK24,STK26,SVIP,SYK,SYVN1,SZT2,TAF9,TAF9B,TAOK1,TAOK2,TERF2,TERF2IP,TERT,TEX15,TFIP11,TGFB2,THOC1,THOC5,THY1,TIAM1,TIGAR,TIMELESS,TIRAP,TLDC1,TLR3,TLR4,TLR6,TLR9,TMBIM6,TMEM161A,TMEM189-UBE2V1,TMEM33,TNF,TNFRSF11A,TNFRSF19,TNFSF11,TNIK,TNR,TP73,TPD52L1,TPR,TPT1,TRAF2,TRAF4,TRAF6,TRAP1,TRIAP1,TRIM28,TRIM32,TRIP12,TWIST1,TXN,UBAC2,UBE2G2,UBE2J1,UBE2N,UBE2V2,UBQLN1,UBR5,UBXN1,UIMC1,ULK4,UNC5CL,USP1,USP13,USP14,USP25,USP47,VANGL2,VASH1,VEGFA,VHLL,VNN1,WDR76,WFS1,WNT1,WNT16,WNT5A,WNT7A,WNT7B,XBP1,XDH,XRCC1,YBX3,YOD1,YPEL3,YWHAE,ZC3H12A,ZNF277,ZNF365,ZNF385A,ZNF622,ZNF675	TetrapodAncestor	218.58
GO.Biological.Process	GO:0035295	tube.development	89	4.592838e-223	5.932569e-219	6.665808e-221	1.199828e+0	AARD,ABCA12,ABL1,ACAT1,ACVR2B,ACVRL1,ADA,ADAMTS16,ADAMTS2,ADAMTSL2,ADGRG1,AGR2,AHI1,AKR1B1,ALX1,ALX4,AMBRA1,APAF1,AQP1,AQP11,AQP2,AR,AREG,ARG1,ARG2,ARHGAP35,ARID1A,ARL13B,ASCL1,ASXL1,ATOH8,ATP6AP2,ATXN1L,B4GALT1,BAG6,BBS4,BBS7,BCAS3,BCL10,BCL2,BCL2L11,BMP2,BMP4,BMP5,BMP7,BMPER,BMPR1A,BMPR2,BRIP1,BTRC,C1GALT1,C2CD3,CALB1,CASR,CAT,CBFA2T2,CCBE1,CCDC103,CCDC40,CCKBR,CCL11,CCM2,CCNB1,CDKN1A,CEBPA,CECR2,CELSR1,CER1,CFL1,CHD7,CHD8,CHI3L1,CHRD,CITED1,CITED2,CLDN18,CLMP,COBL,COL3A1,CPS1,CREB1,CRISPLD2,CSF1,CSF1R,CSNK2B,CTGF,CTNNB1,CTSH,CTSZ,CXCL8,CYP1A1,CYP1A2,DAB1,DAB2IP,DACT1,DACT2,DCHS1,DDR1,DEAF1,DHCR7,DLC1,DLG1,DLG5,DLL1,DLL4,DNAAF1,DPPA2,DPPA4,DVL1,DVL3,EDA,EDAR,EDN1,EDN2,EDNRB,EFNB2,EGF,EGFR,EIF4E,EIF4EBP1,EN1,ENG,EP300,EPAS1,EPB41L5,EPCAM,EPHA2,EPHA4,EPHA7,EPHB3,ERRFI1,ESR1,ESRP2,EYA1,FAM212A,FAT4,FERD3L,FGF1,FGF10,FGF18,FGF2,FGF7,FGF9,FGFR1,FGFR2,FLT4,FMN1,FOXA1,FOXC1,FOXC2,FOXE1,FOXF1,FOXF2,FOXH1,FOXJ1,FOXL1,FOXN4,FOXP2,FSTL3,FUZ,FZD1,FZD2,FZD3,FZD6,GATA2,GATA3,GATA4,GATA5,GATA6,GBX2,GDF11,GDF2,GDNF,GLI2,GLI3,GNA13,GPC3,GREM1,GRHL2,GRHL3,GSC,GZF1,HAND1,HAND2,HECA,HEG1,HES1,HES3,HES5,HEYL,HHEX,HIF1A,HIKESHI,HLX,HMGB1,HNF1B,HOXA1,HRH2,HS6ST1,HSD11B1,HSPB11,ID1,ID2,IFT140,IFT172,IFT52,IFT57,IGFBP5,IHH,ING2,INTU,ITGA3,ITGB4,ITPK1,JAG1,JMJD6,KDM2B,KDM5B,KDM6A,KIF18A,KIF20B,KIF26B,KLF2,KLF5,KLHL3,KRAS,LAMA5,LBX1,LEF1,LGR4,LGR5,LHX1,LHX2,LIF,LIPA,LMO4,LOX,LOXL3,LRP5,LRP6,LUZP1,MAN1A2,MAN2A1,MAPK1,MAPK3,MEF2C,MEGF8,MESP1,MET,MIB1,MIXL1,MKKS,MKS1,MMP14,MSX2,MTHFD1,MTHFD1L,MTSS1,MYC,MYCN,MYOCD,NDRG4,NF1,NFATC4,NFIA,NFIB,NIPBL,NKX2-3,NKX2-5,NKX2-6,NKX3-1,NKX3-2,NOG,NOS3,NOTCH1,NOTCH4,NOTO,NPHP3,NR4A3,NRP1,NUMB,OSR1,OTC,OVOL2,OXTR,PAK1,PAX2,PAX7,PAX8,PBX1,PCSK5,PDGFA,PDGFC,PDGFRB,PDPN,PFN1,PGR,PHACTR4,PHEX,PHF14,PITX2,PKD1,PKD2,PKDCC,PLXNA2,PLXNB2,PLXND1,PML,PODXL,POU3F3,PRDM1,PRICKLE1,PRKACA,PRKD2,PRKX,PROX1,PSEN1,PTCH1,PTK7,PTN,RAD21L1,RALA,RARA,RARB,RARG,RARRES2,RASIP1,RB1,RBP4,RBPJ,RBPMS2,RC3H2,RDH10,REC8,RET,ROBO2,RSPO2,RYR2,SALL2,SCRIB,SCT,SDC4,SEC24B,SEMA3C,SEMA3E,SEMA4C,SERPINE2,SETD2,SETDB2,SFRP1,SFRP2,SHOX2,SHROOM3,SIM1,SIM2,SIX2,SKI,SLC23A1,SLC4A2,SLIT2,SMAD2,SMAD4,SMAD5,SMAD7,SMO,SOSTDC1,SOX10,SOX11,SOX17,SOX18,SOX4,SOX8,SOX9,SPINT1,SPRY1,SPRY2,SRC,SREBF1,SRF,SSBP3,ST14,STARD13,STAT1,STIL,STK4,STRA6,SUFU,T,TAB1,TACSTD2,TBC1D20,TBC1D32,TBX1,TBX2,TBX20,TBX3,TBX5,TCF21,TEAD2,TFAP2B,TGFB1,TGFB2,TGFBR2,TGM2,THRA,THRB,TIGAR,TIMELESS,TMED2,TMEM107,TNC,TNF,TNS3,TP63,TRAF3IP1,TRAF4,TRAF6,TRIM71,TSC2,TULP3,TWIST1,TYMS,UMOD,VANGL2,VASP,VDR,VEGFA,VPS52,WNK4,WNT1,WNT11,WNT3A,WNT4,WNT5A,WNT6,WNT7A,WNT7B,WNT9B,YIPF6,ZEB1,ZFP36L1,ZFPM2,ZIC3,ZNF358	TetrapodAncestor	218.227
GO.Biological.Process	GO:0010243	response.to.organonitrogen.compound	90	7.034392e-220	9.086324e-216	1.009592e-217	1.191432e+0	AACS,AANAT,ABAT,ABCB4,ABCC2,ABCC8,ABL1,ACTR2,ADA,ADAMTS13,ADCY2,ADCY3,ADCY4,ADCY5,ADCY8,ADGRL3,ADIPOQ,ADORA2A,ADRB2,ADSS,AGER,AGRP,AGT,AGTR1,AGTR2,AGTRAP,AGXT,AHCYL1,AIF1,AIFM1,AKAP6,AKR1B1,AKT2,ALAD,ALDH3A1,ANXA1,AOC1,AP3S1,APC,APEX1,APLP1,APOBEC1,APP,APPL1,AQP1,AQP8,AREG,ARG1,ARHGEF2,ARID1B,ASCL1,ASNS,ATF4,ATP1A2,ATP2B4,ATP6AP1,ATP6V0A4,ATP6V0B,ATP6V0C,ATP6V0D1,ATP6V0D2,ATP6V0E1,ATP6V0E2,ATP6V1B1,ATP6V1B2,ATP6V1C1,ATP6V1C2,ATP6V1D,ATP6V1E1,ATP6V1E2,ATP6V1G1,ATP6V1G3,ATP6V1H,AVP,AVPR1A,AVPR1B,AVPR2,BAD,BAIAP2L2,BCAR1,BCHE,BCL11A,BCL2,BCL2L1,BIRC2,BMP7,BRAF,BRCA1,BRIP1,BSG,BTG2,C2CD5,CA2,CACNA1A,CACNA1S,CACNA2D1,CACNB1,CACYBP,CAMK2A,CAPN10,CAPN2,CARM1,CASP1,CASP3,CASP4,CASP6,CASQ2,CASR,CASTOR1,CAT,CAV1,CAV2,CAV3,CCKAR,CCL2,CCNA2,CCND1,CD36,CD40,CDC5L,CDC6,CDH1,CDK1,CDK4,CDK5,CDKN1A,CDKN1B,CDO1,CEBPB,CFL1,CFLAR,CFTR,CHRNA2,CHRNA3,CHRNA5,CHRNA6,CHRNB2,CHRNB3,CHRNB4,CHRND,CHRNE,CHRNG,CHUK,CIB2,CITED1,CNGA3,CNR1,CNR2,COL16A1,COL1A1,COL1A2,COL3A1,COL5A2,COL6A1,CPEB1,CPEB2,CPEB4,CPS1,CREB1,CRHBP,CRHR1,CRHR2,CRK,CRLS1,CRY1,CSH1,CSK,CTGF,CTNNA1,CTNNB1,CYBA,CYBB,CYC1,CYFIP1,DBH,DDC,DDX11,DENND4C,DGKQ,DHFR,DHODH,DHX15,DIAPH1,DMTN,DNM2,DNMT3A,DNMT3B,DNTT,DRD1,DRD2,DRD3,DRD4,DRD5,DUOX1,DUOX2,DUSP1,EDN1,EEF2,EEF2K,EFTUD2,EGFR,EGR1,EGR2,EIF2B1,EIF2B3,EIF2B4,EIF2B5,EIF4EBP1,EIF6,ENPP1,ENSG00000255439,ENSG00000278139,EPHA4,EPM2AIP1,EREG,ERRFI1,EZH2,EZR,F7,FABP3,FADD,FDX1,FER,FGF21,FIS1,FKBP1A,FOS,FOSB,FOSL1,FOXC2,FOXO1,FOXO4,FUNDC1,GAB1,GABPA,GABRB1,GABRB2,GABRB3,GABRG2,GAL,GCGR,GCK,GCLM,GGH,GH1,GH2,GHR,GHRHR,GHSR,GIP,GJA1,GLDC,GLP1R,GLP2R,GLRA1,GLRA2,GLRA3,GLRA4,GLRB,GNAI1,GNAO1,GNAT3,GNB2,GNG10,GNG11,GNG12,GNG13,GNG2,GNG3,GNG7,GNG8,GNRH1,GNRHR,GOT1,GPD1,GPER1,GPIHBP1,GPLD1,GPR22,GPRC6A,GRB2,GRIN1,GRIN2A,GRM5,GSK3A,GSN,GSS,GSTM2,GSTP1,HADHA,HCN1,HCN2,HCN3,HCN4,HCRTR1,HCRTR2,HDAC2,HDAC5,HDAC8,HDAC9,HHEX,HLCS,HMGCS1,HMOX1,HNMT,HNRNPD,HOMER1,HPCA,HPRT1,HSD11B2,HSF1,HSP90AB1,HSP90B1,HSPA5,HTR1B,HTR2A,HTR3A,ID1,IDE,IGF1,IGF1R,IGF2,IGFBP5,IL10,IL13,IL1B,IL6,INAVA,INHBB,INPP5K,INS,INSIG2,IPO5,IQGAP1,IRAK3,IRS1,IRS2,IRS4,ITGA2,ITPR2,JAG1,JAK2,JAK3,JUN,JUNB,JUP,KALRN,KAT2B,KAT7,KCNC1,KCNC2,KCNE1,KCNJ11,KCNK1,KCNQ1,KDM1A,KHK,KL,KLF1,KLF10,KLF11,KLF15,KLF2,KLF3,KLF4,KLF5,KYNU,LAMTOR2,LAMTOR3,LAMTOR4,LARP1,LARS,LDHA,LEP,LPIN1,LRP1,LRP5,LRP6,LRRK2,LYN,LYPD1,MAP1LC3A,MAPK1,MAPK14,MAPK3,MAS1,MAX,MBD1,MC4R,MDM2,MEF2C,MEN1,MGARP,MGST1,MGST2,MGST3,MMP19,MSX1,MTHFR,MTOR,NAIP,NDEL1,NDUFS4,NEFL,NEURL1,NFKB1,NGFR,NKX6-1,NLRP1,NME1,NME2,NNMT,NOD1,NOTCH1,NOX4,NPFF,NPFFR2,NR1H4,NR4A1,NR4A2,NR4A3,NTRK1,NTRK2,OGG1,OGT,OPA1,OPRK1,OPRM1,OR56A1,OR56A4,OR5T3,OTC,OXT,OXTR,P2RX2,P2RX3,P2RX4,P2RX5,P2RX6,P2RX7,PAK1,PANX1,PARP1,PAX4,PCK1,PCNA,PDE1B,PDE2A,PDE3A,PDE4B,PDE4D,PDGFC,PDGFD,PDK2,PDPK1,PDXP,PEA15,PEMT,PENK,PER1,PFKFB1,PHEX,PHIP,PIK3C2A,PIK3C3,PIK3CA,PIK3CG,PIK3R1,PIK3R2,PIK3R3,PKD2,PKLR,PKM,PLA2G1B,PLA2G5,PLN,PNPT1,POR,PPARA,PPARG,PPARGC1A,PPARGC1B,PPP1R9B,PPP2R2A,PPP3CA,PPP5C,PRKAA1,PRKACA,PRKACG,PRKAR1A,PRKAR1B,PRKAR2B,PRKCD,PRKCE,PRKCG,PRKCI,PRKCZ,PRKDC,PRKN,PRL,PRLH,PRLR,PSEN1,PTAFR,PTEN,PTK2,PTK2B,PTN,PTPN1,PTPN22,PTPRA,PXN,QDPR,QRFPR,RAB13,RAB31,RAB8A,RAD51,RANBP2,RAP1A,RAP1B,RAPGEF1,RAPGEF2,RAPGEF3,RBBP4,RECQL5,RELA,REN,RETN,RHOQ,RIPK2,RNF40,RNLS,RPE65,RPL23,RPTOR,RRAGA,RRAGD,RRM2B,RYR1,RYR2,RYR3,SDK1,SELL,SESN2,SESN3,SFRP1,SH2B2,SH3BP4,SHC1,SHMT1,SIRT1,SIRT2,SLC1A2,SLC22A6,SLC25A33,SLC26A3,SLC27A1,SLC2A1,SLC2A8,SLC30A10,SLC34A1,SLC38A9,SLC5A5,SLC6A3,SLC6A4,SLC7A11,SLC8A1,SLC8A3,SLC9A1,SLIT2,SMARCC1,SMPD1,SNCA,SOCS1,SOCS2,SOCS7,SOD1,SOGA1,SORBS1,SOS1,SOX9,SP1,SPAAR,SPIDR,SRC,SRD5A1,SRD5A2,SREBF1,SRR,SRSF4,SRSF5,SRSF6,SRSF9,SST,STAR,STAT1,STC1,STC2,STXBP4,TAC1,TACR3,TAF1,TBC1D4,TCIRG1,TEK,TFF1,TGFB1,TH,THBD,TIAM1,TIMELESS,TIMP1,TIMP4,TLR2,TLR4,TLR6,TMBIM6,TMED10,TNF,TNFAIP3,TNFSF10,TP53,TP73,TRDMT1,TREM2,TRIB3,TRPC3,TRPM2,TRPV1,TSHR,TSPO,TUSC5,TYMS,TYR,UBE3A,UBR1,UBR2,UCP2,UCP3,UFL1,UMODL1,UPRT,UQCRC1,USF1,VAMP2,VCAM1,WDTC1,WNT1,WNT10B,XBP1,XRN1,YWHAG,ZEB1,ZFP36L1,ZNF106,ZNF354A	TetrapodAncestor	215.042
GO.Biological.Process	GO:0050870	positive.regulation.of.T.cell.activation	91	1.486055e-219	1.919537e-215	2.109382e-217	1.418312e+0	ADA,ADAM8,AGER,AIF1,ANXA1,AP3D1,BAD,BCL10,BCL6,BTLA,CARD11,CAV1,CCDC88B,CCL19,CCL2,CCL21,CCL5,CCR2,CD1D,CD209,CD24,CD247,CD27,CD274,CD276,CD28,CD3D,CD3E,CD3G,CD46,CD47,CD5,CD55,CD59,CD6,CD74,CD80,CD83,CD86,CDC42,CLECL1,CORO1A,CSK,CTLA4,DHPS,DNAJA3,DOCK8,DUSP10,EBI3,EFNB1,EFNB2,EFNB3,EPO,FADD,FAM49B,FLOT2,FOXP3,GATA3,GLI2,GLI3,GPAM,GRAP2,GRB2,HAVCR2,HES1,HHLA2,HLX,HMGB1,HSPH1,ICOS,IFNG,IGF1,IGF2,IGFBP2,IHH,IL12A,IL12B,IL12RB1,IL15,IL18,IL1B,IL1RL2,IL2,IL21,IL23A,IL23R,IL36B,IL4,IL6,IL6ST,IL7,IL7R,ITPKB,JAK3,KIRREL1,KLRK1,LCK,LEP,LGALS1,LGALS9,LILRB2,LILRB4,LYN,MALT1,MAP3K14,MAP3K7,MAP3K8,MYB,NCK1,NCK2,NCKAP1L,NPHS1,PAK1,PAK2,PAK3,PDCD1,PDCD1LG2,PDPK1,PIK3CA,PIK3R1,PIK3R6,PNP,PRKCQ,PRKCZ,PTPN11,PYCARD,RAC1,RAG1,RARA,RASAL3,RASGRP1,RIPK2,RPS3,SART1,SASH3,SELENOK,SHB,SIRPG,SOCS1,SOCS5,SPN,SRC,SYK,TESPA1,TFRC,TGFB1,TGFBR2,THY1,TMIGD2,TNFRSF13C,TNFRSF14,TNFSF11,TNFSF13B,TNFSF14,TNFSF9,TRAF2,TRAF6,VAV1,VCAM1,VNN1,VTCN1,XBP1,XCL1,YES1,ZAP70,ZBTB1,ZBTB16,ZMIZ1,ZP3,ZP4	TetrapodAncestor	214.717
GO.Biological.Process	GO:0014070	response.to.organic.cyclic.compound	92	1.206057e-217	1.557864e-213	1.693330e-215	1.179467e+0	AACS,AANAT,ABAT,ABCA1,ABCA2,ABCA3,ABCB4,ABCC2,ABCD3,ABHD2,ABL1,ACACB,ACAT1,ACSBG1,ACSL1,ACSL3,ACTR2,ADA,ADAM9,ADAR,ADCY2,ADCY3,ADCY5,ADCYAP1,ADCYAP1R1,ADGRL3,ADIPOQ,ADORA2A,ADSS,AGL,AGO1,AGO2,AGO3,AGO4,AGT,AGTR2,AGXT,AIF1,AIFM1,AKAP6,ALAD,ALDH3A1,ALPL,AMH,ANGPT2,ANKRD1,ANXA1,ANXA3,AOC1,APEX1,APLP1,APOA2,APOA4,APOB,APP,AQP1,AQP3,AQP8,AR,AREG,ARG1,ARID1A,ARNT2,ARPC1B,ASCL1,ASNS,ATF4,ATP1A1,ATP1A2,ATP2B1,ATP2B4,AVP,AVPR1A,BAD,BAK1,BCHE,BCL2,BCL2L1,BECN1,BGLAP,BID,BIRC2,BMP2,BMP4,BMP6,BMP7,BRAF,BRCA1,BSG,BTG2,BTRC,CA2,CA9,CACNA1S,CALCOCO1,CALCR,CALR,CARM1,CASP1,CASP3,CASP6,CASP8,CASP9,CASQ2,CASR,CAT,CATSPER1,CATSPER2,CATSPER4,CATSPERB,CATSPERD,CAV1,CBL,CCL1,CCL2,CCL3,CCL5,CCNA2,CCNB1,CCND1,CCNE1,CCR5,CD36,CD38,CD40,CD83,CDC5L,CDH1,CDK1,CDK4,CDK5,CDK7,CDKN1A,CDKN1B,CDKN2D,CDO1,CEBPA,CEBPB,CFLAR,CFTR,CHEK2,CHKA,CHRNA2,CHRNA3,CHRNA5,CHRNA6,CHRNB2,CHRNB3,CHRNB4,CHRND,CHRNE,CHRNG,CIB2,CIDEA,CITED1,CLDN1,CLDN4,CNGA3,CNR1,COL1A1,COLEC12,CPN1,CPS1,CPT1A,CREB1,CRHBP,CRLS1,CRYAB,CSNK2A1,CSNK2B,CTGF,CTNNA1,CTNNB1,CXCL10,CYBA,CYBB,CYP1A1,CYP1A2,CYP1B1,CYP24A1,CYP27B1,CYP7A1,DAXX,DDIT4,DDX1,DDX17,DDX18,DDX21,DDX5,DDX54,DDX58,DGKQ,DHFR,DHODH,DHX9,DIAPH1,DMTN,DNAJA1,DNM1L,DNM2,DNMT3A,DNMT3B,DNTT,DRD1,DRD2,DRD3,DRD4,DRD5,DROSHA,DSG1,DSG2,DUOX1,DUOX2,DUSP1,DUSP6,DYNAP,EDN1,EDNRB,EEF2,EEF2K,EFNA5,EFTUD2,EGFR,EGLN2,EGR1,EIF4A3,EIF4E,EIF4EBP1,ELK1,ENDOG,ENG,ENSG00000255439,EPHX1,EPO,ERCC8,ERRFI1,ESR1,ESR2,ESRRA,ESRRB,ESRRG,ETS1,EZH2,EZR,F7,FADD,FAM210B,FAS,FBXO32,FDX1,FGF10,FGF23,FHL2,FIBIN,FIS1,FKBP1A,FKBP1B,FKBP4,FLOT1,FNTB,FOS,FOSB,FOSL1,FOXA1,FOXF1,FOXO1,FOXP2,G6PD,GABPA,GABRB1,GABRB2,GABRB3,GABRG2,GBA,GCLM,GDAP1,GH1,GHRHR,GHSR,GIP,GLB1,GLDC,GLI2,GNAI1,GNAO1,GNAT3,GNG2,GNRH1,GOT1,GPD1,GPER1,GPLD1,GPR83,GRIN1,GRIP1,GSK3A,GSN,GSTM2,GSTP1,H2AFZ,HAMP,HBE1,HCFC1,HCN1,HCN2,HCN3,HCN4,HDAC2,HDAC5,HDAC8,HEY1,HID1,HLCS,HMGB1,HMGB2,HMGCS1,HMOX1,HNF1B,HNF4A,HNF4G,HNMT,HNRNPA2B1,HNRNPD,HNRNPU,HOMER1,HPCA,HPGD,HSD11B2,HSF1,HSP90AB1,HSP90B1,HSPA5,HTR1B,HTR2A,HTR3A,HTR5A,ID1,ID3,IFIT1,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNB1,IFNE,IFNK,IFNW1,IGFBP2,IGFBP5,IGFBP7,IHH,IL10,IL13,IL15,IL18,IL1B,IL1RN,IL22,IL4,IL6,INHBA,INPP5K,IRAK3,IRF3,ISL1,ITGA2,ITPR2,JAK2,JUN,JUNB,JUP,KALRN,KAT5,KCNC2,KCNE1,KCNJ11,KCNJ8,KCNK1,KCNMB1,KCNQ1,KDM1A,KDM3A,KIF18A,KLF2,KLF4,KLF5,KLF9,KRAS,KYNU,LARP1,LDHA,LEF1,LEP,LGALS1,LIN28A,LIN28B,LONP2,LOX,LRP6,LRP8,LRRK2,LUM,LY6D,LYN,LYPD1,MAOB,MAP1LC3A,MAPK1,MAPK3,MB21D1,MBD1,MBD2,MBD3,MDK,MDM2,MED13,MED14,MED17,MED24,MED30,MED4,MEF2C,METTL21C,METTL3,MGARP,MLC1,MMP14,MMP15,MMP19,MSN,MSR1,MSTN,MSX1,MSX2,MTHFR,MTOR,MUL1,MYOD1,MYOG,NAMPT,NASP,NCBP1,NCOA1,NCOA3,NCOA4,NCOA6,NDUFS4,NEDD8,NEFL,NFATC4,NFKB1,NKX3-1,NKX6-1,NME1,NOTCH1,NOX4,NPAS4,NPC1,NPFF,NPM1,NQO1,NR0B1,NR0B2,NR1D1,NR1D2,NR1H2,NR1H3,NR1H4,NR1I2,NR2C1,NR2C2,NR2E3,NR2F6,NR3C1,NR4A1,NR4A2,NR4A3,NR5A2,NRIP1,NTRK1,NTRK3,OGG1,OPRK1,OPRL1,OPRM1,OR51E2,OR56A1,OR56A4,OR5T3,OTC,OXT,OXTR,P2RX2,P2RX3,P2RX4,P2RX5,P2RX6,P2RX7,P2RY1,P2RY6,PADI2,PAK2,PAK3,PAK4,PAM,PANX1,PAPPA,PAQR5,PAQR6,PAQR7,PAQR8,PARP1,PAX4,PCK1,PCK2,PCNA,PDCD7,PDE12,PDE2A,PDE3A,PDE4B,PDE4D,PDGFB,PDGFRB,PDXP,PEA15,PELI1,PENK,PER1,PFKFB1,PGR,PGRMC2,PHB,PHEX,PIAS1,PIAS2,PIK3CG,PIM1,PKD2,PKLR,PLA2G4F,PLA2G5,PLIN2,PLN,PLPP1,PMAIP1,PMEPA1,PMVK,PNPT1,POU4F1,PPARA,PPARD,PPARG,PPARGC1A,PPARGC1B,PPP1R9B,PPP2R2A,PPP5C,PQBP1,PRKAA1,PRKACA,PRKAR2B,PRKCE,PRKCG,PRKN,PRKRA,PSPH,PTAFR,PTCH1,PTEN,PTGER2,PTGES,PTGFR,PTH,PTK2B,PTN,PTPRU,RAD51,RAE1,RALB,RAMP2,RAP1A,RAP1B,RAPGEF1,RAPGEF2,RAPGEF3,RARA,RARB,RARG,RB1,RBBP7,RBBP8,RBFOX2,RBM14,RECQL5,RELA,REN,REST,RFTN1,RFTN2,RIOK3,RIPK2,RNF14,RNF4,RNLS,ROCK2,RORB,RORC,RUVBL2,RWDD1,RXRA,RXRB,RXRG,RYR1,RYR2,RYR3,S100B,SAFB,SCGB1A1,SDK1,SELL,SFRP1,SHMT1,SIRT2,SLC16A1,SLC22A6,SLC26A3,SLC26A5,SLC34A1,SLC3A2,SLC5A5,SLC6A3,SLC6A4,SLC7A11,SLC8A1,SLC8A3,SLC9A1,SLIT2,SLIT3,SMAD2,SMAD5,SMO,SMPD1,SMYD3,SNCA,SNIP1,SOCS2,SOD1,SOX10,SOX30,SPIDR,SPOUT1,SPP1,SRC,SRD5A1,SRD5A2,SREBF1,SRR,SRRT,SRSF2,SST,SSTR1,SSTR2,SSTR3,SSTR4,SSTR5,STAR,STAT1,STC1,STC2,STXBP1,TAC1,TACR3,TADA3,TAF1,TAF2,TARBP2,TAT,TBXA2R,TEK,TERT,TET2,TFPI,TGFB1,TGFB1I1,TGFB2,TGFBR1,TGFBR2,TH,THBD,THBS1,THRA,THRAP3,THRB,TIAM1,TICAM1,TIPARP,TLR2,TLR3,TMEM173,TNC,TNF,TPCN2,TPH2,TRIM25,TRIM63,TRIM71,TRIP4,TRPA1,TRPC3,TRPM2,TRPV1,TSN,TSNAX,TSPO,TXN2,TXNIP,TYMS,TYR,UBE2L3,UBE3A,UBR5,UCN,UCN3,UCP3,UGT1A1,UGT3A2,USP8,UTS2,VCAM1,VDR,WFDC1,WNT10B,WNT7A,WNT7B,WNT8B,XRN1,YAP1,YWHAH,ZC3H12A,ZC3H7A,ZCCHC11,ZFP36,ZFP36L1,ZFP36L2,ZNF354A,ZNF703	TetrapodAncestor	212.807
GO.Biological.Process	GO:1903708	positive.regulation.of.hemopoiesis	93	7.030517e-217	9.081319e-213	9.764859e-215	1.424560e+0	ACIN1,ACVR1B,ACVR2A,ADA,ADAM8,AGER,ANKRD54,ANXA1,AP3D1,ATP11C,ATP6AP1,ATXN1L,AXL,BAD,BCL6,BTK,CA2,CASP8,CCL19,CCR1,CD101,CD27,CD46,CD74,CD80,CD83,CD86,CREB1,CSF1,CSF3,DUSP10,ETS1,FADD,FAM210B,FES,FLT3LG,FOS,FOXC1,FOXP3,GAS6,GATA2,GATA3,GLI2,GLI3,GNAS,GPR68,HAX1,HCLS1,HIF1A,HLX,HMGB1,HMGB2,IFNG,IHH,IL12A,IL12B,IL12RB1,IL15,IL17A,IL18,IL1RL2,IL2,IL20,IL23A,IL23R,IL34,IL36B,IL4,IL5,IL6,IL7,IL7R,INHBA,INPP5D,ISG15,ITPKB,JAG1,JUN,KITLG,KLF10,LEF1,LEP,LGALS9,LIF,LILRB2,LILRB4,MAPK14,MMP14,MYB,NCKAP1L,OCSTAMP,PCID2,PDCD2,PF4,PIK3R6,PNP,POU4F1,PPARGC1B,PPP2R3C,PRDM1,PRKCA,PRKCZ,PRMT1,RAB7B,RAG1,RARA,RASGRP1,RB1,RIPK1,RIPK2,ROR2,RUNX1,SART1,SASH3,SCIN,SHB,SLC9B2,SMAP1,SOCS1,SOCS5,STAT1,SYK,TAL1,TESC,TESPA1,TGFB1,TGFBR2,THPO,TMEM64,TNF,TNFSF11,TNFSF9,TRAF6,TRIB1,VNN1,XBP1,ZAP70,ZBTB1,ZBTB16,ZFP36L1,ZMIZ1,ZNF16	TetrapodAncestor	212.042
GO.Biological.Process	GO:0043086	negative.regulation.of.catalytic.activity	94	1.415968e-214	1.829006e-210	1.945751e-212	1.199702e+0	A2M,A2ML1,ABL1,ACACB,ADAR,ADARB1,ADCYAP1,ADIPOQ,ADORA2A,ADRA2A,AGT,AHSG,AIDA,AIP,AJUBA,AKT1S1,AMBP,AMOT,ANAPC1,ANAPC11,ANAPC16,ANAPC2,ANAPC4,ANAPC5,ANGPTL4,ANOS1,ANP32E,ANXA1,ANXA3,ANXA4,ANXA5,AOC3,APBA3,APC,APLP2,APOA1,APOA2,APOC1,APOC3,APOE,APP,AQP1,ARFGEF3,ARL2,ARL6IP1,ARRB1,ARRB2,ASPN,ATP2B4,ATPIF1,ATR,AVP,BAG4,BBS4,BCAS3,BCL2L12,BGN,BICD1,BIRC2,BIRC3,BIRC5,BIRC6,BMP4,BMP7,BST2,C14orf166,C3,C4A,C4B,C5,CABIN1,CABP1,CAMK2N1,CAMK2N2,CAMSAP3,CAND1,CARD16,CARD17,CARD18,CASP3,CASP8,CAST,CAV1,CAV3,CBL,CBLB,CBLC,CCAR2,CCDC8,CCNB1,CCR2,CD109,CD27,CD2BP2,CD300A,CD44,CD46,CDC16,CDC20,CDC23,CDC26,CDC27,CDC42SE1,CDK1,CDK2,CDK5RAP1,CDKN1A,CDKN1B,CDKN1C,CDKN2A,CDKN2B,CDKN2C,CDKN2D,CEBPA,CEP192,CEP85,CERS1,CHAD,CHCHD10,CHMP6,CHORDC1,CHP1,CIB1,CISH,CLN3,CNN3,CNR1,CNR2,CNST,COL28A1,COL4A3,COL6A3,COL7A1,COX11,CPAMD8,CPEB2,CR1,CRB2,CRIM1,CRY2,CRYAB,CSK,CSNK2A1,CST6,CST7,CSTA,CSTB,CYP27B1,DAB2IP,DAOA,DBNDD2,DCN,DDX3X,DEPTOR,DFFA,DGKI,DHCR24,DLG2,DLG3,DNAJA1,DNAJB6,DPEP1,DRD2,DRD3,DRD4,DRD5,DTNBP1,DTX3L,DUS2,DUSP1,DUSP10,DUSP16,DUSP18,DUSP19,DUSP2,DUSP21,DUSP22,DUSP26,DUSP3,DUSP6,DUSP7,DUSP8,DUSP9,DVL1,EDNRB,EGLN1,EIF4A2,ELFN1,ELFN2,ENSG00000177359,ENSG00000214776,ENSG00000273734,EPHA1,EPHB2,EPPIN,EPPIN-WFDC6,ERRFI1,F11R,FABP1,FABP4,FAF2,FAM212A,FAM212B,FARP1,FBXO5,FBXO7,FETUB,FGFR1OP,FKBP15,FKBP1A,FKBP1B,FLRT1,FLRT2,FLRT3,FOXA2,FRY,FURIN,FZD10,FZR1,GADD45A,GADD45B,GALR2,GALR3,GAPDH,GAS6,GBA,GCHFR,GCKR,GGNBP2,GLA,GMFB,GMFG,GNAQ,GP1BA,GPATCH2,GPC3,GPR87,GPRC5A,GPS1,GRM2,GRM3,GRXCR1,GSK3A,GSKIP,GSTP1,GZMA,H2AFY,HERPUD1,HEXIM1,HEXIM2,HGF,HHEX,HMGCR,HMSD,HNRNPR,HNRNPU,HP,HPCA,HRAS,HRG,HRH3,HSPB1,HSPBP1,IBTK,IFI6,IFIT1,IGBP1,IGF1R,IKBKB,IL13,IL1B,IL6,IL7,INCA1,INPP5K,INS,IPO5,IQGAP1,IRAK3,IRS2,ITIH1,ITIH3,ITIH4,ITIH6,KAT2B,KDM5A,KLF4,KLRK1,KNG1,KNL1,LAMP3,LATS1,LATS2,LAX1,LCN1,LEF1,LEPR,LIMK1,LMTK2,LMTK3,LPA,LRCH1,LRP5,LRP6,LRRC15,LRRC19,LRRC3,LRRC3C,LRRC4,LRRC4C,LRRC66,LRRK2,LRRTM1,LRRTM3,LRRTM4,LRTM1,LRTM2,LTB4R2,LXN,LYN,MAD2L1,MAD2L2,MAPK8IP1,MAPT,MARCO,MARF1,MASTL,MBIP,MDM2,MEN1,MICAL1,MKKS,MLLT1,MMP9,MPHOSPH10,MSTN,MTRR,MVP,MYO1D,MYOCD,NAIP,NCK1,NCKAP1L,NEIL1,NES,NF1,NF2,NFKB1,NGF,NGFR,NIFK,NIPSNAP2,NLE1,NLRC4,NLRP7,NOL3,NOS1,NOS3,NOSIP,NOTCH1,NPM1,NPR3,NPRL2,NQO1,NUP62,OAZ1,OAZ2,OAZ3,OPRM1,OR56A1,OR56A4,OR5T3,OXA1L,PAK2,PALM,PAPLN,PARK7,PARP9,PAX2,PCDH11X,PCID2,PCIF1,PCSK1N,PDE6D,PDE6H,PDPK1,PDZD3,PHACTR1,PHACTR2,PHACTR3,PHPT1,PI15,PI16,PI3,PICALM,PIF1,PIH1D1,PIK3IP1,PINLYP,PINX1,PKIA,PKIB,PKIG,PKMYT1,PKN1,PLIN5,PLK1,PLN,PODN,PODNL1,POR,POT1,PPARG,PPIF,PPM1E,PPM1F,PPME1,PPP1R10,PPP1R12A,PPP1R14B,PPP1R14C,PPP1R14D,PPP1R15A,PPP1R17,PPP1R1A,PPP1R1C,PPP1R2,PPP1R26,PPP1R27,PPP1R2P3,PPP1R2P9,PPP1R35,PPP1R36,PPP1R37,PPP1R8,PPP1R9B,PPP2R5A,PPP4R4,PRDX3,PRDX5,PREX1,PRKAG2,PRKAR1A,PRKAR1B,PRKAR2B,PRKCA,PRKCD,PRKCZ,PRKN,PRKRIP1,PROS1,PRPSAP1,PRPSAP2,PSEN1,PSMA2,PSMA3,PSMA4,PSMB1,PSMB10,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTEN,PTN,PTPA,PTPN1,PTPN22,PTPRJ,PTPRN2,PTTG1,PTTG2,PTX3,PYCARD,PYDC1,PZP,R3HDML,RAF1,RAG1,RB1,RBM26,RCC2,RDX,RECK,RENBP,RFFL,RGN,RGS14,RGS2,RGS3,RGS4,RNF34,RNH1,ROCK2,RPL11,RPL23,RPL5,RPS27A,RPS6KA1,RPS6KA3,RPS7,RPTOR,RRP1B,RTKN,RTN4R,RTN4RL2,RUBCN,SAG,SCG5,SCGB1A1,SEMA4D,SERPINA1,SERPINA10,SERPINA11,SERPINA12,SERPINA3,SERPINA4,SERPINA5,SERPINA6,SERPINA7,SERPINA9,SERPINB1,SERPINB10,SERPINB11,SERPINB12,SERPINB13,SERPINB2,SERPINB3,SERPINB4,SERPINB5,SERPINB6,SERPINB7,SERPINB8,SERPINB9,SERPINC1,SERPIND1,SERPINE2,SERPINE3,SERPING1,SERPINH1,SERPINI1,SERPINI2,SFI1,SFN,SFRP1,SFRP2,SH2D4A,SH3BP4,SH3BP5,SH3RF1,SH3RF2,SHB,SIAH2,SIRT1,SLC7A14,SLIT2,SLN,SLPI,SMAD7,SMCR8,SMPD1,SMYD3,SNCA,SNCB,SNX6,SOCS1,SOCS2,SOCS3,SOCS4,SOCS5,SOCS6,SOCS7,SORL1,SPINK1,SPINK13,SPINK14,SPINK4,SPINK5,SPINK6,SPINK7,SPINK9,SPINT1,SPINT3,SPINT4,SPOCD1,SPOCK1,SPOCK2,SPOCK3,SPP2,SPRED1,SPRED2,SPRY1,SPRY2,SRC,SRCIN1,SSPO,STK38,SYTL2,TARBP2,TERF1,TERF2,TESC,TFAP2B,TFIP11,TFPI,TFPI2,TGFB2,THBS1,THY1,TIMP1,TIMP2,TIMP3,TIMP4,TIPRL,TLR9,TMBIM1,TMBIM6,TMED2,TMEM132D,TMEM225,TNF,TNFAIP3,TNFAIP8,TNFRSF10A,TNFRSF10B,TNFRSF10C,TNFRSF10D,TNFRSF1B,TNFSF14,TNK2,TNNI3,TNNT2,TP53,TP73,TRIAP1,TRIB1,TRIB2,TRIB3,TSC2,TSG101,TSKS,TXNIP,UBASH3B,UBC,UBE2C,UBE2D1,UBE2E1,UBN1,UBXN1,UCHL1,UCHL5,UGT1A1,UGT1A8,UMODL1,USP14,USP47,UVSSA,VCPKMT,VEGFA,VIL1,VPS25,VTN,WARS,WDR81,WDTC1,WEE2,WFDC1,WFDC10A,WFDC12,WFDC13,WFDC2,WFDC3,WFDC5,WFDC6,WFDC8,WFIKKN1,WNK1,WNT9A,WWTR1,XIAP,YWHAE,YWHAG,ZCCHC9,ZFP36,ZFYVE1,ZFYVE28,ZNF675	TetrapodAncestor	209.738
GO.Biological.Process	GO:0043409	negative.regulation.of.MAPK.cascade	95	6.711715e-214	8.669522e-210	9.125813e-212	1.463056e+0	ABL1,ADIPOQ,AIDA,AMBP,APOE,ARRB1,ASH1L,ATF3,BMP4,BMP7,C1QL4,C3orf33,CAMK2N1,CAV1,CAV3,CBLC,CD300A,CNKSR3,CRYBA1,CSK,DAB2IP,DACT1,DLG1,DNAJA1,DUSP1,DUSP10,DUSP16,DUSP18,DUSP19,DUSP2,DUSP21,DUSP22,DUSP26,DUSP3,DUSP6,DUSP7,DUSP8,DUSP9,EFNA1,EIF3A,EPHB2,ERRFI1,EZR,F2RL1,FBLN1,FKTN,FLCN,FOXM1,FOXO1,GBA,GPER1,GPS1,GSTP1,HDAC3,HMGCR,HSPH1,IGBP1,IGF1R,IL1B,INPP5K,IRAK3,ITCH,KLF4,LAX1,LEMD2,LIF,LMO3,LYN,MAPK8IP1,MARVELD3,MBIP,MECOM,MEN1,MYC,NF1,NF2,NLRP6,NUP62,P2RX7,PAFAH1B1,PBK,PER1,PHB,PIK3R2,PIN1,PINK1,PPEF2,PRKCD,PRKN,PSCA,PSMD10,PTEN,PTPN1,PTPN22,PTPRJ,PTPRR,RANBP9,RAPGEF1,RGS14,RGS2,RGS3,RGS4,RNF149,RPS6KA6,SERPINB3,SFRP1,SFRP2,SIRT3,SLC9A3R1,SMAD4,SMPD1,SORL1,SPRED1,SPRED2,SPRY1,SPRY2,SPRY4,STK38,SYNJ2BP,TBC1D10C,TIMP3,TLR4,TNIP1,TP73,UCHL1,VRK3,WNK2,ZNF675	TetrapodAncestor	209.062
GO.Biological.Process	GO:0001501	skeletal.system.development	96	1.513853e-212	1.955444e-208	2.036921e-210	1.223254e+0	ABI1,ACAN,ACD,ACP2,ACP5,ACVR2A,ACVR2B,ADAMTS4,AEBP1,AES,AHSG,AKAP13,ALPL,ALX1,ALX4,AMELX,AMER1,ANKH,ANO6,ARID5B,ARSE,ASH1L,ASXL1,AXIN2,BARX2,BBX,BCAN,BGLAP,BMP1,BMP2,BMP4,BMP5,BMP6,BMP7,BMP8A,BMP8B,BMPR1A,BMPR1B,BMPR2,CARM1,CD44,CDH11,CDKN1C,CDX1,CER1,CHAD,CHD7,CHI3L1,CHRD,CHRDL2,CHST11,CLEC3A,CMKLR1,CNMD,COL10A1,COL11A1,COL12A1,COL13A1,COL1A1,COL1A2,COL27A1,COL2A1,COL3A1,COL5A2,COL9A2,CREB3L2,CSGALNACT1,CSRNP1,CTGF,CTNNB1,CYP26B1,CYR61,CYTL1,DCANP1,DCHS1,DEAF1,DHRS3,DLG1,DLL3,DLX5,DSCAML1,DSPP,DYM,EDN1,EIF2AK3,EIF4A3,EN1,ENG,ENSG00000243696,EP300,EPHA2,ESRRA,ETS2,EVC,EXT1,EXTL1,EYA1,FAM20C,FAT4,FBN2,FGF18,FGF2,FGF4,FGF6,FGF9,FGFR1,FGFR2,FGFR3,FGFRL1,FLI1,FLVCR1,FMN1,FOXC1,FOXC2,FOXN3,FREM1,FUZ,GDF10,GDF11,GDF2,GDF3,GDF5,GH1,GLG1,GLI2,GLI3,GNA11,GNAQ,GNAS,GPLD1,GRHL2,GSC,HAND1,HAND2,HAPLN1,HAPLN2,HAPLN3,HAS2,HDAC4,HES5,HES7,HIF1A,HMGA2,HOXA1,HSPB11,IFITM5,IFT140,IFT172,IGF1,IGF2,IGFBP4,IHH,IL17F,IMPAD1,INHA,INSIG2,ITGB8,JAG2,KIAA1217,KLF10,LECT2,LEP,LHX1,LRP5,LRP6,LRRC17,LUM,MAPK14,MAPK3,MATN1,MATN3,MBTD1,MCPH1,MDFI,MEF2C,MEF2D,MEGF8,MEIS1,MEPE,MEX3C,MGP,MIGA2,MKKS,MKS1,MMP13,MMP14,MMP16,MMP9,MSX1,MSX2,MTHFD1,MTHFD1L,MUSTN1,MYCN,NAB2,NDST1,NEUROG1,NFIB,NIPBL,NKX3-2,NLE1,NOG,NOV,NPPC,NPR2,NPR3,NSD2,OSR1,OTOR,P2RX7,P3H1,PAFAH1B1,PAPPA2,PAPSS2,PAX5,PAX7,PBX1,PCGF2,PCSK5,PDGFC,PEX7,PHEX,PHOSPHO1,PIP4K2A,PITX1,PITX2,PKD1,PKDCC,PLEKHA1,PLS3,PLXNB1,POC1A,PPARGC1B,PPIB,PRDX1,PRELP,PRKRA,PRPSAP2,PRRX1,PSEN1,PTGER4,PTH,PTH1R,PTHLH,PTPN11,RAB23,RAB33B,RAI1,RANBP3L,RARA,RARB,RARG,RASSF2,RBP4,RDH10,RFLNB,RIPPLY1,RIPPLY2,ROR2,RPL38,RPS6KA3,RSPO2,RUNX1,RUNX2,RYR1,SATB2,SBDS,SCX,SEMA4D,SERP1,SERPINH1,SETD2,SFRP1,SFRP2,SFRP4,SGPL1,SHOX,SHOX2,SIX2,SKI,SLC39A3,SMAD2,SMAD5,SNAI1,SNAI2,SNX19,SOX11,SOX4,SOX9,SPNS2,SPP2,SRC,SRD5A1,SRD5A2,SRF,STC1,SUFU,SULF2,T,TAL1,TAPT1,TBX1,TBX15,TBX3,TCF15,TCOF1,TEAD4,TEK,TFAP2A,TGFB1,TGFB2,TGFBI,TGFBR1,TGFBR2,THBS3,THRA,TIFAB,TIMP1,TIPARP,TLL1,TMEM110-MUSTN1,TNFRSF11B,TP63,TRIM45,TRIP11,TRPS1,TULP3,TWIST1,TYMS,UFD1,USP1,VCAN,VDR,VKORC1,VPS33B,WASF2,WDR5,WDR60,WFIKKN1,WNT1,WNT10B,WNT11,WNT5A,WNT7A,WNT7B,WNT9A,WNT9B,WWOX,ZBTB16,ZEB1,ZFAND5,ZFPM1,ZNF385A	TetrapodAncestor	207.709
GO.Biological.Process	GO:0045765	regulation.of.angiogenesis	97	2.971554e-211	3.838356e-207	3.957068e-209	1.349726e+0	ABCC8,ABL1,ACVRL1,ADAMTS9,ADGRA2,ADGRB1,ADGRB2,ADGRB3,ADM2,AGGF1,AGT,AMOT,ANGPT2,ANGPT4,ANGPTL4,ANXA3,APELA,APLNR,APOH,AQP1,BRCA1,BTG1,C3,C3AR1,C5,C6,CCBE1,CCL11,CCL2,CCR2,CCR3,CD34,CD40,CHI3L1,CIB1,CNMD,COL4A3,CTNNB1,CTSH,CX3CL1,CX3CR1,CXCL10,CXCL13,CXCL8,CYBB,CYP1B1,CYSLTR2,DAB2IP,DCN,DDAH1,DLL1,DLL4,ECSCR,EFNA1,EFNA3,EGLN1,EMP2,ENG,ENPP2,EPHA1,EPHA2,ERAP1,ERBB2,ETS1,F3,FAM129B,FASLG,FGF1,FGF2,FLT1,FOXC1,FOXC2,FOXO4,GAB1,GATA2,GATA4,GATA6,GDF2,GHSR,GPNMB,GPR4,GREM1,GTF2I,HDAC5,HDAC7,HDAC9,HGF,HHEX,HIF1A,HIPK1,HIPK2,HMGA2,HMGB1,HMOX1,HRG,HSPB1,HSPB6,HSPG2,ID1,IL17F,IL1A,IL1B,IL6,ISL1,ITGA5,ITGB2,JCAD,KLF4,KRIT1,KRT1,LEP,LRG1,MEOX2,MMRN2,MTDH,MYDGF,NF1,NGFR,NOS3,NOTCH1,NPR1,NRP1,PDCD10,PDCD6,PDCL3,PF4,PGK1,PIK3R6,PLCG1,PLXND1,PML,PPARG,PPP1R16B,PRKCA,PRKCB,PRKD1,PRKD2,PROK1,PROK2,PTGIS,PTK2B,PTN,PTPRM,RAMP2,RAPGEF3,RGCC,RLN2,RNH1,ROCK2,RRAS,RUNX1,SARS,SASH1,SEMA3E,SEMA4A,SEMA5A,SFRP1,SFRP2,SIRT1,SIRT6,SP100,SPHK1,SPINK5,SPRED1,SRPX2,STARD13,STAT1,STIM1,SYNJ2BP,TBXA2R,TEK,TERT,TGFBR2,THBS1,THBS2,THBS4,TIE1,TMEM2,TMIGD2,TNFAIP3,TNFRSF12A,TNFSF12,TNMD,TSPAN12,TWIST1,UTS2,UTS2R,VASH1,VASH2,VEGFA,VEGFB,VEGFC,VEGFD,WARS,WNT5A,XBP1,ZC3H12A	TetrapodAncestor	206.416
GO.Biological.Process	GO:0040008	regulation.of.growth	98	3.339820e-211	4.314045e-207	4.402087e-209	1.201046e+0	ABL1,ACACB,ACVR1B,ACVRL1,ADAM15,ADIPOR1,ADIPOR2,ADNP,ADNP2,ADRB2,ADRB3,AES,AFG3L2,AGR2,AGRN,AGT,AGTR1,AGTR2,AKAP6,ALOX15B,ANAPC2,APBB2,APOE,APP,AR,ARHGAP4,ARHGEF11,ARMC10,ARX,ATP8A2,ATRN,AVP,AVPR1A,BAP1,BASP1,BBS4,BCAR1,BCL11A,BCL2,BCL2L11,BCL6,BDKRB1,BDNF,BLZF1,BMP10,BMP4,BMPR1A,BMPR2,BNIPL,BRAT1,BRD8,BRMS1L,BST2,BTG1,CACNA2D2,CAMK2D,CAPRIN2,CARM1,CAV3,CCAR2,CCDC85B,CCNB1,CD36,CD38,CDA,CDC42,CDC73,CDH4,CDHR2,CDK1,CDK19,CDK4,CDK5,CDK5R1,CDKL5,CDKN1A,CDKN1B,CDKN2A,CDKN2AIP,CDKN2C,CDKN2D,CHD7,CHPT1,CIB1,CISH,COLQ,CPNE5,CPNE6,CRABP2,CREB1,CREG1,CRIM1,CRLF3,CRYAB,CSF1,CSNK2A1,CSNK2A3,CTDP1,CTGF,CTTN,CXCL16,CYBA,CYFIP1,CYP27B1,CYR61,DAB2IP,DACT3,DCAF1,DCBLD2,DCC,DCUN1D3,DDR1,DDX3X,DERL2,DIO3,DISC1,DLL1,DMAP1,DNM2,DPYSL2,DRAXIN,DRD2,DRD3,DSCAM,DUSP10,DUSP6,E4F1,EBAG9,EDN1,EFNA5,EGFR,EGLN2,EI24,EIF4G2,ENPP1,EPB41L3,EPC1,EPHA7,ERBB2,ERBB4,ESM1,ESR2,EXOSC2,EXOSC4,EXOSC9,EXTL3,EZR,F2,FAM107A,FBLN5,FBP1,FGF13,FGF2,FGF20,FGF9,FGFR1,FGFR1OP,FGFR2,FGFR3,FLCN,FLVCR1,FN1,FOXC1,FOXC2,FOXS1,FSTL4,FXN,FXYD2,G6PD,GAL,GAP43,GAS6,GATA6,GDF2,GDF5,GDI1,GH1,GHR,GHRH,GHRHR,GHSR,GJA1,GOLGA4,GPAM,GPAT4,GPC3,GPR21,GREM1,GSK3A,H3F3A,H3F3C,HAMP,HBEGF,HDGFL2,HEPACAM,HEY2,HIF1A,HLX,HMGA2,HNF1B,HNF4A,HPN,HRG,HSF1,HTRA1,HTRA2,HTRA3,HTRA4,IFNG,IFRD1,IGF1,IGFBP2,IGFBP4,IGFBP5,IGFBP6,IGFBP7,IGFBPL1,IGSF11,IHH,IL10,IL12B,IL17RB,IL2,IL7,IL9,ING2,ING3,ING5,INHBA,INO80,INS,IRF8,ISLR2,IST1,ITCH,ITSN2,JADE1,JARID2,KAT5,KAZALD1,KCNK2,KCTD21,KCTD6,KDM2B,KIAA1109,KIF26A,KRT17,L1CAM,LAMTOR2,LATS1,LATS2,LBP,LEF1,LEP,LGMN,LIMK1,LMX1A,LPAR3,LTBP4,LUZP4,MACF1,MAD2L2,MAEL,MAG,MAP1B,MAPK11,MAPK14,MAPT,MBL2,MCTS1,MEF2C,MEGF8,MEIS1,MKKS,MMP14,MORF4L1,MORF4L2,MPO,MRGBP,MSTN,MSX1,MTM1,MTOR,MTPN,MUC12,MUL1,MUSK,MYOCD,MYOD1,N6AMT1,NAIF1,NANOS1,NCBP1,NDEL1,NDRG3,NDUFS3,NEDD4L,NEDD9,NET1,NIPBL,NKX2-5,NKX6-1,NOG,NOTCH1,NOTCH2,NOV,NPPC,NPR1,NPY1R,NRG1,NRG3,NRK,NRP1,NSMCE3,NTRK3,OGFR,OLFM1,OSBP,OSGIN1,OSGIN2,OSM,OSTN,PAFAH1B1,PAK1,PAK2,PAPPA2,PHB,PHLDA2,PIK3CA,PIM1,PIN1,PLAA,PLAC8,PLCB1,PLCE1,PLS1,PLXNA1,PLXNA2,PLXNA3,PLXNA4,PML,PNPT1,POR,POU1F1,POU3F2,PPARD,PPARG,PPIB,PPM1F,PPP1R9B,PPT1,PRKCQ,PRKDC,PRKN,PRL,PRLH,PROX1,PRSS2,PSMD10,PTCH1,PTEN,PTK2,PTK2B,PTPN11,PTPRJ,PTPRS,RAB21,RAG2,RAI1,RASAL1,RASGRP2,RB1,RBBP7,RBP4,RBPJ,RERG,RIMS1,RND2,RNF6,ROS1,RPS6KA1,RPS6KA3,RPTOR,RTN4,RTN4R,RUFY3,RUVBL1,RUVBL2,S100A8,S100A9,SASH3,SCGB3A1,SDCBP,SEMA3A,SEMA3G,SEMA4D,SEMA5A,SEMA7A,SERP1,SERPINE2,SERTAD2,SESN2,SFN,SFRP1,SFRP2,SGK1,SGK2,SGPL1,SH3BP4,SHC1,SIPA1,SIRT1,SLC25A33,SLC6A3,SLC6A4,SLC9A1,SLIT2,SLIT3,SMAD4,SMARCA2,SMARCA4,SMO,SMURF1,SOCS1,SOCS2,SOCS3,SOCS4,SOCS5,SOCS6,SOCS7,SOD1,SOX15,SOX17,SPAAR,SPHK1,SPOCK1,SPP1,SQSTM1,SRF,ST7L,STC2,STK4,SYT1,SYT17,SYT2,SYT4,TAF9,TAF9B,TAOK2,TBX2,TBX20,TBX5,TFCP2L1,TGFB1,TGFB2,TGFBR1,TGFBR2,TIRAP,TKT,TLL2,TMC8,TMEM8B,TMEM97,TNF,TNFRSF12A,TNKS2,TNR,TP53,TP53TG5,TP73,TRIM32,TRO,TRPC5,TSG101,TSPYL5,TTL,TWF2,UBE2E3,UCN,ULK2,UNC13A,USP47,UTS2R,VEGFA,VIL1,WDR36,WFDC1,WFS1,WISP1,WISP2,WNT11,WNT3,WNT3A,WNT5A,WRN,WWC1,WWC2,WWC3,YBX3,YEATS4,ZFPM2,ZFYVE27,ZMAT3,ZNF639,ZP3,ZPR1	TetrapodAncestor	206.365
GO.Biological.Process	GO:0010632	regulation.of.epithelial.cell.migration	99	1.953134e-209	2.522863e-205	2.548347e-207	1.337882e+0	AAMP,ABL1,ACVRL1,ADAM9,ADAMTS9,ADGRA2,ADGRB1,ADIPOR1,AGT,AGTR2,AMOTL1,ANGPT1,ANGPT2,ANGPT4,ANXA3,APOE,APOH,AQP1,ATOH8,ATP5A1,BCAR1,BCAS3,BMP10,BMP4,BMPER,BMPR2,CALR,CAPN7,CCBE1,CCR6,CD40,CIB1,CLASP1,CLASP2,CSNK2B,CTSH,CXCL13,DAB2IP,DCN,DLL4,DOCK5,DUSP10,EDN1,EFNA1,EMP2,ENPP2,EPB41L4B,EPB41L5,EPHA2,ETS1,EVL,FGF1,FGF10,FGF16,FGF18,FGF2,FGF4,FGF7,FGFR1,FLT4,FOXC2,GATA3,GDF2,GLIPR2,GPLD1,HAS2,HBEGF,HDAC5,HDAC7,HDAC9,HIF1A,HMGB1,HRG,HSPB1,IFNG,IL4,INSL3,ITGA2,ITGA3,JCAD,JUN,KLF4,KRIT1,MACF1,MARVELD3,MCC,MEOX2,MET,MMP9,MMRN2,MTOR,NF1,NOTCH1,NRP1,NRP2,P2RX4,PBLD,PDCD10,PDCD6,PDGFB,PDPK1,PFN1,PFN2,PLCG1,PLPP3,PPARG,PPM1F,PRCP,PRKCA,PRKCE,PRKD1,PRKD2,PROX1,PTEN,PTK2,PTK2B,PTPN23,PTPRG,PTPRM,PTPRR,RAB25,RGCC,ROCK2,RREB1,RTN4,SASH1,SCARB1,SEMA3A,SEMA4A,SEMA5A,SH3BP1,SLIT2,SOX9,SP100,SPRED1,SRC,SRPX2,STARD13,STC1,STRAP,SYNJ2BP,TAC1,TACSTD2,TDGF1,TEK,TGFB1,TGFB2,TGFBR2,THBS1,VASH1,VEGFA,VEGFC,VIL1,WNT5A,WNT7A,ZC3H12A,ZNF580	TetrapodAncestor	204.598
GO.Biological.Process	GO:0070372	regulation.of.ERK1.and.ERK2.cascade	100	2.417237e-209	3.122345e-205	3.122345e-207	1.330829e+0	ABL1,ACKR3,ADCYAP1,ADIPOQ,ADRA1A,AGER,ALKAL1,ALOX15,ANGPT1,APIP,APP,ARAF,ARHGAP8,ARRB1,ARRB2,ATF3,ATP6AP1,BMP2,BMP4,BMPER,BRAF,C1QL4,C3orf33,CALCR,CAMK2N1,CAVIN3,CCL1,CCL11,CCL13,CCL14,CCL15,CCL15-CCL14,CCL16,CCL17,CCL18,CCL19,CCL2,CCL21,CCL22,CCL23,CCL3,CCL3L3,CCL4,CCL4L2,CCL5,CCL7,CCL8,CCR1,CCR7,CD36,CD44,CD74,CFLAR,CHI3L1,CIB1,CNKSR3,CRYBA1,CSF1R,CSK,CTGF,CX3CL1,CYR61,CYSLTR2,DAB2IP,DDT,DLG1,DNAJC27,DRD2,DSTYK,DUSP1,DUSP10,DUSP26,DUSP3,DUSP6,EGFR,EIF3A,EPHA2,EPHA7,EPHB1,EPHB2,EPO,ERBB2,ERBB4,ERRFI1,EZR,F2R,F2RL1,FAM83D,FBLN1,FBXW7,FFAR4,FGF1,FGF10,FGF18,FGF19,FGF2,FGF20,FGF21,FGF23,FGF4,FGFR2,FGFR3,FGFR4,FGG,FLCN,FLT4,FN1,FRS2,FSHR,GAREM1,GAS6,GCNT2,GLIPR2,GPER1,GPNMB,GPR183,GPR55,GSTP1,HAND2,HAVCR2,HCRTR1,HMGB1,HMGCR,HRAS,HTR2A,HTR2B,HTR2C,IL1B,IL26,IL6,JUN,KARS,KLF4,LGALS9,LIF,LMO3,LYN,MAP2K2,MAPK3,MARCO,MIF,NDRG4,NECAB2,NEK10,NLRP6,NOD1,NOTCH1,NOTCH2,NOX4,NPTN,NPY5R,NQO2,NRP1,NTRK1,OPRM1,P2RY1,PDE8A,PDGFA,PDGFB,PDGFC,PDGFD,PDGFRB,PHB,PIN1,PKHD1,PLA2G2A,PLA2G5,PRKCA,PRKCZ,PRKD2,PRMT5,PSCA,PTEN,PTK2B,PTPN1,PTPN11,PTPN22,PTPRR,PYCARD,RAF1,RANBP9,RAP1A,RAP1B,RAPGEF1,RAPGEF2,RASGRP1,RGS14,RIPK2,ROS1,RPS6KA6,RRAS,S100A7,SEMA7A,SHC1,SIRT3,SLC30A10,SLC9A3R1,SMAD4,SPRY1,SPRY2,SPRY4,SRC,STYX,SYK,SYNJ2BP,TBC1D10C,TEK,TGFB1,THPO,TIAM1,TIMP3,TIRAP,TLR4,TNF,TNFAIP8L3,TNFRSF11A,TNFSF11,TNIP1,TREM2,VRK3,WNK2,XCL1,XCL2	TetrapodAncestor	204.506
GO.Biological.Process	GO:0033673	negative.regulation.of.kinase.activity	101	5.831659e-209	7.532754e-205	7.458172e-207	1.335555e+0	ABL1,ADAR,ADARB1,ADIPOQ,ADORA2A,AIDA,AJUBA,AKT1S1,APC,APOE,ASPN,BGN,BMP4,BMP7,C14orf166,CAMK2N1,CAMK2N2,CASP3,CAV1,CAV3,CBL,CBLB,CBLC,CD300A,CDK5RAP1,CDKN1A,CDKN1B,CDKN1C,CDKN2A,CDKN2B,CDKN2C,CDKN2D,CEBPA,CEP85,CHAD,CHMP6,CHORDC1,CHP1,CIB1,CISH,COX11,CSK,DAB2IP,DBNDD2,DCN,DEPTOR,DNAJA1,DTNBP1,DUS2,DUSP1,DUSP10,DUSP16,DUSP18,DUSP19,DUSP2,DUSP21,DUSP22,DUSP26,DUSP3,DUSP6,DUSP7,DUSP8,DUSP9,DVL1,EPHA1,EPHB2,ERRFI1,FABP4,FAM212A,FAM212B,FBXO7,FGFR1OP,FLRT1,FLRT2,FLRT3,FOXA2,GADD45A,GADD45B,GBA,GCKR,GGNBP2,GMFB,GMFG,GNAQ,GP1BA,GPRC5A,GPS1,GSKIP,GSTP1,H2AFY,HEXIM1,HEXIM2,HHEX,HMGCR,HNRNPU,HSPB1,IBTK,IGF1R,IL1B,IL6,INCA1,INPP5K,IRAK3,IRS2,KAT2B,LATS1,LATS2,LAX1,LRP5,LRP6,LRRC15,LRRC19,LRRC3,LRRC3C,LRRC4,LRRC4C,LRRC66,LRRTM1,LRRTM3,LRRTM4,LRTM1,LRTM2,LYN,MAPK8IP1,MAPT,MBIP,MEN1,MLLT1,MSTN,MVP,MYOCD,NCK1,NF1,NF2,NPM1,NPRL2,NUP62,PAK2,PARK7,PDPK1,PIK3IP1,PKIA,PKIB,PKIG,PKN1,PLK1,PODN,PODNL1,PPM1E,PPM1F,PPP1R1A,PPP1R1C,PPP2R5A,PRDX3,PREX1,PRKAG2,PRKAR1A,PRKAR1B,PRKAR2B,PRKCD,PRKN,PRKRIP1,PSEN1,PTEN,PTPN1,PTPN22,PTPRJ,PYCARD,PYDC1,RB1,RGN,RGS14,RGS2,RGS3,RGS4,RPTOR,RTN4R,RTN4RL2,RUBCN,SERPINB3,SFN,SFRP1,SFRP2,SH3BP5,SHB,SIRT1,SMCR8,SMPD1,SMYD3,SNX6,SOCS1,SOCS2,SOCS3,SOCS4,SOCS5,SOCS6,SOCS7,SORL1,SPRED1,SPRED2,SPRY1,SPRY2,SRCIN1,STK38,TARBP2,TESC,THY1,TNFAIP3,TP73,TRIB1,TRIB2,TRIB3,TSC2,TSG101,UBASH3B,UCHL1,UVSSA,VPS25,WARS,WEE2,WNK1,WWTR1,YWHAG,ZFYVE28,ZNF675	TetrapodAncestor	204.123
GO.Biological.Process	GO:0030036	actin.cytoskeleton.organization	102	1.117629e-208	1.443641e-204	1.415335e-206	1.269456e+0	ABI1,ABI2,ABL1,ABLIM2,ABLIM3,ABR,ACTN1,ACTN4,ACTR2,ACTR3,ACTR3B,ACTR3C,ADD1,ADRA2A,AIF1,ALDOA,ALKBH4,AMOT,ANKRD1,ANTXR1,ANXA1,AQP1,ARAP1,ARF1,ARF6,ARHGAP12,ARHGAP25,ARHGAP26,ARHGAP35,ARHGAP6,ARHGEF11,ARHGEF17,ARHGEF2,ARPC1A,ARPC1B,ARPC2,ARPC4,ARPC4-TTLL3,ARPC5,ARRB1,ATXN3,AUTS2,BAIAP2L2,BCAR1,BCL2,BCL6,BCR,BIN3,BMP10,BRSK2,CALR,CAP1,CAP2,CAPN10,CAPZB,CARMIL1,CARMIL2,CASQ1,CASQ2,CATIP,CAV3,CAVIN3,CCDC155,CCL11,CD2AP,CDC42,CDC42BPA,CDC42BPB,CDC42BPG,CDC42EP2,CDK5,CFL1,CFL2,CFLAR,CLRN1,CNN1,CNN3,COBL,CORO1A,CORO1B,CORO2B,CORO6,CSRP3,CTNNA1,CTTN,CUL3,CXADR,CXCL1,CYTH2,DAAM1,DAAM2,DBN1,DIAPH1,DIAPH2,DIAPH3,DLC1,DLG1,DMTN,DNAJB6,DOCK2,DPYSL3,DSTN,DTNBP1,EHD2,ELMO1,EMP2,ENSG00000284292,EPB41,EPB41L1,EPB41L2,EPB41L3,EPB41L4A,EPB41L4B,EPB41L5,EPS8,ESPN,ESPNL,EVL,EZR,F11R,FAT1,FER,FGD1,FGD2,FGD3,FGD4,FGD5,FGF10,FGF7,FHL3,FHOD3,FLII,FLNA,FLNB,FMN1,FMN2,FMNL1,FMNL2,FMNL3,FOXJ1,FRMD3,FRMD5,FRMD6,FRY,FRYL,FSCN1,FSCN3,GAB1,GAS2L3,GDPD2,GHSR,GPR65,GSN,HCLS1,HSP90B1,IGSF22,IKBKB,INF2,INPP5K,INSRR,IQSEC2,IQSEC3,ITGB1,ITGB5,ITPKA,JAK2,JMY,KCTD13,KLHL1,KLHL17,KPTN,KRAS,KRT19,LCP1,LDB3,LIMA1,LIMCH1,LIMK1,LMOD1,LMOD3,LURAP1,MAD2L2,MAPKAP1,MARCKS,MEF2A,MICAL1,MICAL3,MINK1,MKLN1,MOB2,MSRB2,MTSS1,MYBPC1,MYBPC2,MYBPC3,MYBPH,MYH10,MYH14,MYH3,MYH6,MYH9,MYLK3,MYO18A,MYO1B,MYOM2,MYOM3,MYOZ3,MYPN,NCK1,NCK2,NCKAP1L,NEBL,NEDD9,NF1,NF2,NISCH,NKX2-5,NPHP1,NPHP4,NPHS2,NRP1,NUAK2,OBSCN,OPHN1,PACSIN2,PAFAH1B1,PAK1,PAK2,PAK4,PAK5,PALLD,PARVB,PARVG,PAWR,PDCD6IP,PDGFA,PDGFRB,PDLIM3,PDLIM4,PDLIM7,PDPK1,PDXP,PFN1,PFN2,PFN3,PHACTR1,PHACTR4,PIP5K1A,PIP5K1C,PLA2G1B,PLEK,PLEK2,PLS1,PLS3,POF1B,PPARGC1B,PREX1,PRKAR1A,PRKCI,PRKCZ,PRKG1,PROX1,PTK2B,PTK7,PTPN1,RAB13,RAC1,RAC2,RAC3,RACGAP1,RALA,RAP1GDS1,RAP2A,RFLNA,RFLNB,RHOD,RHOG,RHOJ,RHOQ,RHOU,RICTOR,RND1,RND3,ROCK2,RUFY3,S1PR1,SBK2,SCIN,SDAD1,SDCBP,SH3BP1,SHC1,SHROOM4,SIPA1L1,SLC9A3R1,SORBS1,SORBS2,SORBS3,SPIRE1,SPIRE2,SPTBN5,SRC,SRF,SSH2,STRIP1,TAOK2,TBCK,TESK2,TLN1,TMOD1,TMOD2,TMOD3,TMOD4,TMSB4Y,TNF,TNFAIP1,TNIK,TNNT2,TNXB,TPM2,TPM3,TPM4,TRIM32,TRIOBP,TRIP10,TRPM7,TTC17,TTN,USH1C,VASP,VIL1,WASF2,WDR1,XIRP1,ZYX	TetrapodAncestor	203.841
GO.Biological.Process	GO:0051348	negative.regulation.of.transferase.activity	103	1.967747e-208	2.541739e-204	2.467708e-206	1.304803e+0	ABL1,ADAR,ADARB1,ADIPOQ,ADORA2A,AIDA,AJUBA,AKT1S1,ANAPC1,ANAPC11,ANAPC16,ANAPC2,ANAPC4,ANAPC5,APC,APOE,ASPN,BGN,BMP4,BMP7,C14orf166,CAMK2N1,CAMK2N2,CASP3,CAV1,CAV3,CBL,CBLB,CBLC,CCNB1,CD300A,CDC16,CDC20,CDC23,CDC26,CDC27,CDK1,CDK2,CDK5RAP1,CDKN1A,CDKN1B,CDKN1C,CDKN2A,CDKN2B,CDKN2C,CDKN2D,CEBPA,CEP85,CERS1,CHAD,CHCHD10,CHMP6,CHORDC1,CHP1,CIB1,CISH,COX11,CSK,DAB2IP,DBNDD2,DCN,DEPTOR,DNAJA1,DTNBP1,DTX3L,DUS2,DUSP1,DUSP10,DUSP16,DUSP18,DUSP19,DUSP2,DUSP21,DUSP22,DUSP26,DUSP3,DUSP6,DUSP7,DUSP8,DUSP9,DVL1,EIF4A2,EPHA1,EPHB2,ERRFI1,FABP4,FAM212A,FAM212B,FBXO5,FBXO7,FGFR1OP,FLRT1,FLRT2,FLRT3,FOXA2,FZR1,GADD45A,GADD45B,GBA,GCKR,GGNBP2,GMFB,GMFG,GNAQ,GP1BA,GPRC5A,GPS1,GSK3A,GSKIP,GSTP1,H2AFY,HEXIM1,HEXIM2,HHEX,HMGCR,HNRNPU,HSPB1,IBTK,IGF1R,IL1B,IL6,INCA1,INPP5K,IRAK3,IRS2,KAT2B,LATS1,LATS2,LAX1,LIMK1,LRP5,LRP6,LRRC15,LRRC19,LRRC3,LRRC3C,LRRC4,LRRC4C,LRRC66,LRRTM1,LRRTM3,LRRTM4,LRTM1,LRTM2,LYN,MAD2L1,MAD2L2,MAPK8IP1,MAPT,MBIP,MEN1,MLLT1,MSTN,MVP,MYOCD,NCK1,NF1,NF2,NIPSNAP2,NPM1,NPRL2,NUP62,PAK2,PARK7,PDPK1,PHPT1,PIF1,PIK3IP1,PINX1,PKIA,PKIB,PKIG,PKN1,PLK1,PODN,PODNL1,POT1,PPARG,PPM1E,PPM1F,PPP1R1A,PPP1R1C,PPP2R5A,PRDX3,PREX1,PRKAG2,PRKAR1A,PRKAR1B,PRKAR2B,PRKCD,PRKN,PRKRIP1,PSEN1,PSMA2,PSMA3,PSMA4,PSMB1,PSMB10,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTEN,PTPN1,PTPN22,PTPRJ,PYCARD,PYDC1,RB1,RGN,RGS14,RGS2,RGS3,RGS4,RPL11,RPL23,RPL5,RPS27A,RPS7,RPTOR,RTN4R,RTN4RL2,RUBCN,SERPINB3,SFN,SFRP1,SFRP2,SH3BP5,SHB,SIRT1,SMAD7,SMCR8,SMPD1,SMYD3,SNX6,SOCS1,SOCS2,SOCS3,SOCS4,SOCS5,SOCS6,SOCS7,SORL1,SPRED1,SPRED2,SPRY1,SPRY2,SRC,SRCIN1,STK38,TARBP2,TERF1,TESC,THY1,TNFAIP3,TP53,TP73,TRIB1,TRIB2,TRIB3,TSC2,TSG101,UBASH3B,UBC,UBE2C,UBE2D1,UBE2E1,UCHL1,UVSSA,VPS25,WARS,WEE2,WNK1,WWTR1,YWHAG,ZFP36,ZFYVE28,ZNF675	TetrapodAncestor	203.595
GO.Biological.Process	GO:0045321	leukocyte.activation	104	6.133519e-205	7.922666e-201	7.617949e-203	1.207840e+0	A1BG,ABCA13,ABL1,ACPP,ACTR10,ACTR2,ADA,ADA2,ADAM8,ADAM9,ADGRE3,ADGRE5,ADGRG3,AGA,AGL,AGPAT2,AHSG,AICDA,AIF1,AKAP17A,ALAD,ALDH3B1,ALDOA,ALOX5,ANO6,ANPEP,ANXA1,ANXA3,AOC1,AP1M1,AP2A2,APAF1,APEH,ARG1,ARL8A,ARPC5,ASAH1,ATAD3B,ATG5,ATM,ATP11A,ATP11B,ATP11C,ATP6AP2,ATP6V0C,ATP6V1D,ATP8A1,ATP8B4,AXL,AZI2,B4GALT1,BAG6,BAK1,BANK1,BATF2,BATF3,BAX,BCL11B,BCL2,BCL3,BCL6,BLNK,BMX,BPI,BRAF,BST1,BST2,BTK,C16orf62,C1orf35,C3,C3AR1,C6orf120,CAB39,CALML5,CAMK4,CAND1,CANT1,CAP1,CAPN1,CARD11,CASP8,CAT,CBFB,CBL,CCL19,CCL21,CCL3,CCL5,CCND3,CCR6,CCR7,CCR9,CCT2,CCT8,CD14,CD151,CD180,CD1D,CD2,CD276,CD28,CD300A,CD33,CD36,CD3D,CD3E,CD3G,CD40,CD44,CD47,CD53,CD55,CD58,CD59,CD6,CD63,CD68,CD7,CD74,CD79B,CD80,CD86,CD8A,CD8B,CD93,CDA,CDK13,CDK6,CEBPG,CFP,CHD7,CHGA,CHI3L1,CHIT1,CHRNB2,CHRNB4,CKAP4,CLCF1,CLEC12A,CLEC4C,CLEC4D,CLEC4E,CLEC7A,CLU,CMTM6,CMTM7,COMMD3,COMMD9,CORO1A,COTL1,CPLX2,CPNE3,CPPED1,CR1,CR2,CRACR2A,CREG1,CRISP3,CRISPLD2,CRTC3,CSF1,CSNK2B,CSTB,CTNNB1,CTPS1,CTSA,CTSB,CTSC,CTSD,CTSH,CTSZ,CX3CL1,CX3CR1,CXADR,CXCL1,CXCL6,CXCL8,CXCR1,CXCR2,CXCR5,CYB5R3,CYBA,CYBB,CYFIP1,CYP26B1,CYSTM1,DBNL,DCAF1,DCLRE1C,DDOST,DDX3X,DEGS1,DERA,DGAT1,DHRS2,DIAPH1,DLG1,DLL1,DLL4,DNAJA3,DNAJC13,DNASE1L1,DOCK10,DOCK11,DOCK2,DOCK8,DOK3,DPP7,DSC1,DSG1,DSN1,DSP,DYNC1H1,DYNC1LI1,DYNLL1,DYNLT1,EBI3,EDN1,EDN2,EEF1A1,EEF2,EGR1,EIF2AK4,ELF4,ENPP4,EOMES,EP300,EPHB1,EPX,ERCC1,EXO1,EXOSC3,EXOSC6,F2RL1,FABP5,FADD,FAF2,FAS,FCAR,FCER1G,FCN1,FGL2,FGR,FKBP1A,FKBP1B,FLG2,FLT3LG,FOXN1,FOXP3,FRK,FRMPD3,FTH1,FTL,FUCA1,FUCA2,FUT7,FZD5,FZD7,FZD8,FZD9,GAA,GAPT,GATA3,GDI2,GGH,GLA,GLB1,GLI3,GLIPR1,GM2A,GMFG,GNS,GOLGA7,GON4L,GPR18,GPR183,GPR84,GRN,GSDMD,GSN,GSTP1,GUSB,GYG1,HAVCR2,HBB,HDAC4,HDAC5,HDAC9,HEBP2,HELLS,HHEX,HK3,HMGB1,HMOX2,HNF1A,HP,HPRT1,HPSE,HRNR,HSH2D,HSP90AB1,HSPA8,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNAR1,IFNB1,IFNE,IFNG,IFNK,IFNW1,IGBP1,IGF2R,IKZF1,IKZF3,IL10,IL12B,IL13,IL15,IL18,IL18R1,IL18RAP,IL2,IL21R,IL23A,IL33,IL4,IL6,IL7,IL7R,ILF2,IMPDH1,INS,IQGAP1,IRF1,IRF4,IST1,ITFG2,ITGA4,ITGAM,ITGAV,ITGAX,ITGB1,ITGB2,ITK,ITM2A,ITPKB,JAG2,JAK3,JAML,JMJD6,JUN,JUP,KARS,KCNAB2,KDELR1,KIF13B,KLF6,KLRF2,KLRK1,KMT2E,KPNB1,KRT1,LAIR1,LAMTOR2,LAMTOR3,LAT,LAT2,LAX1,LBP,LCK,LCN2,LCP1,LCP2,LEF1,LEP,LEPR,LFNG,LGALS1,LGALS3,LIG4,LILRB2,LRG1,LRMP,LRRC7,LRRC8A,LTBR,LY6D,LYL1,LYN,LYZ,MAFB,MALT1,MAN2B1,MANBA,MAPK1,MAPK14,MAPT,MCEMP1,MEF2C,MERTK,MFNG,MGAM,MGST1,MIF,MILR1,MLEC,MLH1,MME,MMP25,MMP8,MMP9,MOSPD2,MPO,MS4A1,MS4A3,MSH2,MSH6,MSN,MVP,MYH9,NAPRT,NBEAL2,NBN,NCK1,NCK2,NCKAP1L,NCR1,NCR3,NCSTN,NDRG1,NDUFC2,NFAM1,NFASC,NFKB1,NHEJ1,NHLRC3,NIT2,NKX2-3,NLRC3,NME2,NOTCH2,NPC2,NR4A3,NRAS,NTRK1,OLFM4,OLR1,ONECUT1,ORM1,ORM2,ORMDL3,OSCAR,OSTF1,P2RX7,PADI2,PAFAH1B2,PATZ1,PDAP1,PDXK,PECAM1,PFKL,PGAM1,PGLYRP1,PGM2,PGRMC1,PIGR,PIK3CD,PIK3CG,PIK3R1,PKM,PKNOX1,PKP1,PLA2G2D,PLA2G3,PLAC8,PLAU,PLCG2,PLCL2,PLD1,PLEKHO2,PNP,POLM,POU1F1,POU2F2,PPBP,PPIE,PPP3CA,PPP3CB,PRCP,PRDX1,PRDX4,PREX1,PRG2,PRG3,PRKCB,PRKCD,PRKCE,PRKDC,PRLR,PRSS2,PRSS3,PSAP,PSEN1,PSMA2,PSMB1,PSMB11,PSMB7,PSMC2,PSMC3,PSMD1,PSMD11,PSMD13,PSMD2,PSMD3,PSMD7,PTAFR,PTGER4,PTGES2,PTK2B,PTPN22,PTPRB,PTPRJ,PTPRN2,PTX3,PYCARD,PYGB,QPCT,QSOX1,RAB14,RAB18,RAB24,RAB27A,RAB29,RAB31,RAB37,RAB3D,RAB44,RAB4B,RAB5B,RAB6A,RAB7A,RAB9B,RAC1,RAG1,RAG2,RAP1A,RAP1B,RAP2B,RAP2C,RASGRP1,RBPJ,RC3H1,RC3H2,RELB,RETN,RHOG,RIPK2,RIPK3,RNASET2,RNF168,RNF8,RORC,RPS6,RSAD2,RUNX2,S100A11,S100A12,S100A13,S100A7,S100A8,S100A9,S100P,SATB1,SDCBP,SELL,SEMA4A,SERPINA1,SERPINA3,SERPINB1,SERPINB10,SERPINB12,SERPINB3,SERPINB6,SH2D1B,SHB,SIGLEC9,SIRPA,SIRPB1,SKAP2,SLA2,SLAMF6,SLC11A1,SLC15A4,SLC27A2,SLC2A3,SLC44A2,SLCO4C1,SLPI,SNAP23,SNAP25,SNAP29,SNCA,SNX27,SOX4,SPACA3,SPI1,SPN,SRF,SRP14,STAT6,STBD1,STK11IP,STOM,STXBP2,SURF4,SVIP,SYK,SYNGR1,TARM1,TBC1D10C,TBK1,TCF3,TCIRG1,TCN1,TGFB1,TGFBR2,THEMIS,TICAM1,TICAM2,TIMP2,TLR1,TLR2,TLR3,TLR4,TLR6,TMBIM1,TMC6,TMEM173,TMEM63A,TNFAIP6,TNFRSF1B,TNFRSF4,TNFSF14,TNFSF18,TNFSF8,TOLLIP,TOM1,TPD52,TRAF6,TRAPPC1,TREML2,TRPM2,TRPV1,TTR,TUBB,TUBB4B,TXLNA,TXNDC5,TYRO3,UBR4,ULBP1,ULBP2,ULBP3,VAMP2,VAMP8,VAPA,VAT1,VAV1,VCAM1,VCL,VCP,VNN1,WNT1,WNT4,XRCC5,XRCC6,YPEL5,ZAP70,ZBTB1,ZFP36L1,ZFP36L2,ZFPM1,ZNF683	TetrapodAncestor	200.101
GO.Biological.Process	GO:0051347	positive.regulation.of.transferase.activity	105	1.295610e-204	1.673539e-200	1.593847e-202	1.201741e+0	ABI1,ABL1,ACD,ACE,ACSL1,ACVR2B,ADAM8,ADAM9,ADCY2,ADCY3,ADCY4,ADCY5,ADCY8,ADCYAP1,ADIPOQ,ADNP,ADORA1,ADORA2B,ADRA2A,ADRA2B,ADRA2C,ADRB2,AFAP1L2,AGER,AGT,AJUBA,AKAP13,ALK,ALKAL1,ALS2,AMBRA1,ANAPC1,ANAPC11,ANAPC16,ANAPC2,ANAPC4,ANAPC5,ANGPT1,ANGPT4,ARAF,ARRB1,ARRDC3,ARRDC4,ATG14,ATP2B4,AURKB,AVPI1,BAD,BAK1,BAX,BMI1,BMP2,BMP4,BRAF,BTRC,C1QTNF2,C5,C8orf4,CAB39,CACUL1,CALM1,CALM2,CALM3,CAMK1,CAMKK1,CAMKK2,CARD10,CARD14,CARTPT,CCDC88A,CCL19,CCL21,CCL5,CCNB1,CCND1,CCND2,CCND3,CCNH,CCNK,CCNL1,CCNL2,CCNT2,CCR7,CCT2,CCT4,CD24,CD40,CD74,CD81,CDC14B,CDC16,CDC20,CDC20B,CDC23,CDC25B,CDC26,CDC27,CDC42,CDC6,CDK1,CDK20,CDK5,CDK5R1,CDK5R2,CDKN1A,CDKN1B,CEMIP,CENPE,CHI3L1,CHRNA3,CHTF18,CIB1,CKS1B,CKS2,CLU,COPS8,CRK,CRKL,CSF1,CSF1R,CSK,CSPG4,CTNNB1,CUL1,CXCR4,CYR61,DAB1,DAB2IP,DAXX,DBF4B,DBNL,DCUN1D1,DCUN1D3,DCUN1D4,DCUN1D5,DDR2,DDX3X,DGKQ,DKC1,DKK1,DLG1,DRD2,DRD4,DSCC1,DSTYK,DTX3L,DUSP19,DUSP6,DUSP7,DUSP9,DVL3,DYNAP,ECT2,EDN1,EDN3,EFNA1,EFNA5,EGF,EGFR,EGR1,EIF2AK2,EMP2,EPGN,EPHA4,EPHA8,EPM2AIP1,EPO,ERBB2,ERCC6,EREG,ERN1,ERN2,ERP29,ETAA1,EZH2,F2,F2R,FAM20A,FAM58A,FBXO5,FBXW7,FGD2,FGF1,FGF10,FGF13,FGF18,FGF2,FGFR1,FGFR3,FGR,FLT1,FRS2,FZD10,FZD4,FZD5,FZD8,FZR1,GADD45A,GADD45B,GADD45G,GAS6,GCN1,GH1,GHR,GNG3,GOLGA2,GPRC5B,GREM1,GRHL2,GRM4,GRM5,GSK3A,HACD3,HGF,HMBOX1,HMGB1,HMGN1,HNRNPA2B1,HNRNPD,HRAS,HSP90AB1,HSPA2,HSPA5,HSPH1,HTR2A,HTR2B,IFNG,IGF1,IGF2,IKBKG,IL18,IL1B,INAVA,INS,IQGAP1,IQGAP3,IRAK1,IRGM,IRS1,ITGA1,JAK2,JTB,KARS,KITLG,KLF4,KRAS,LAMTOR2,LAMTOR3,LAT,LCP2,LEP,LMO4,LPAR1,LPAR3,LRP8,LRRK2,LYN,MAD2L1,MADD,MAGEC2,MALT1,MAP2K2,MAP2K3,MAP2K4,MAP2K6,MAP2K7,MAP3K1,MAP3K10,MAP3K11,MAP3K12,MAP3K13,MAP3K14,MAP3K15,MAP3K19,MAP3K2,MAP3K21,MAP3K3,MAP3K4,MAP3K5,MAP3K6,MAP3K7,MAP3K7CL,MAP3K8,MAP3K9,MAP4K1,MAP4K3,MAP4K4,MAPK1,MAPK10,MAPK11,MAPK14,MAPK15,MAPK3,MAPK8IP3,MAPKAP1,MAPKAPK2,MAPKAPK3,MAPKAPK5,MAPRE3,MAPT,MARK2,MAS1,MASTL,MIF,MINK1,MLST8,MMD,MMD2,MOS,MRE11,MRNIP,MST1R,MTCP1,MTOR,MUC20,MUL1,MYC,NAB2,NAF1,NBN,NCF1,NCKAP1L,NEK1,NEK10,NEK4,NEK7,NEURL1,NGF,NKX3-1,NOD1,NOX4,NPM1,NRG1,NRG3,NRK,NTF3,NTRK1,NTRK3,NVL,P2RX7,PABPN1,PAK1,PAK2,PAK3,PAK4,PAK5,PARK7,PARM1,PARN,PARP16,PDCD10,PDE5A,PDE6H,PDGFA,PDGFB,PDGFC,PDGFD,PDGFRB,PDPK1,PEA15,PFKFB1,PFKFB2,PIFO,PIH1D1,PIK3CA,PIK3CG,PIK3R5,PIK3R6,PIN1,PINK1,PKD1,PKD2,PKIB,PKN1,PLA2G1B,PLCE1,PLCG1,PLK1,PNKP,POT1,PPP2R3C,PRKAA1,PRKACA,PRKACG,PRKAG2,PRKAR1A,PRKAR1B,PRKAR2B,PRKCD,PRKCQ,PRKCZ,PRKD1,PRLR,PROK1,PROK2,PROX1,PRR5,PSEN1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTEN,PTK2,PTK2B,PTPN1,PTPN11,RAB1A,RAD50,RAF1,RALB,RANBP2,RAP1A,RAPGEF1,RAPGEF2,RASGRP1,RASSF2,RELN,RFC2,RFC3,RFC4,RGCC,RICTOR,RIPK1,RIPK2,RIPK3,ROBO1,ROR2,RPS27A,RPS3,RPTOR,S100A12,SAA1,SASH1,SBK2,SDC4,SERINC1,SERINC2,SERINC5,SHC1,SHC2,SIRT1,SLC11A1,SLC27A1,SNCA,SNX9,SOD1,SORL1,SPAG9,SPDYA,SPRY2,SRC,SRCIN1,STAP1,STK24,STK26,STK4,STRADA,STRADB,STUB1,SYK,TAB1,TAB2,TAB3,TAOK1,TAOK2,TCL1A,TCL1B,TCP1,TDGF1,TEK,TELO2,TENM1,TGFB1,TGFB2,TGFBR1,TGFBR2,THBS1,TIAM1,TIGAR,TIRAP,TLR3,TLR4,TLR6,TLR9,TMEM189-UBE2V1,TNF,TNFAIP8L3,TNFRSF10A,TNFRSF10B,TNFRSF11A,TNFSF11,TNFSF15,TNIK,TNKS,TOM1L1,TOPORS,TP73,TPD52L1,TPX2,TRAF2,TRAF4,TRAF6,TRAF7,TRIB3,TXN,UBC,UBE2C,UBE2D1,UBE2E1,UBE2I,UBE2L3,UBE2N,UBE2S,UCN,UNC119,VANGL2,VAPB,VAV2,VAV3,VEGFA,VLDLR,WNK1,WNT11,WNT3A,WNT5A,WNT7B,WRAP53,XRCC5,XRCC6,ZFP91,ZNF16,ZNF622	TetrapodAncestor	199.776
GO.Biological.Process	GO:0050867	positive.regulation.of.cell.activation	106	1.497510e-204	1.934334e-200	1.824843e-202	1.321446e+0	ADA,ADAM8,ADORA2B,AGER,AIF1,ANXA1,AP1G1,AP3D1,APP,ATAD5,ATP11C,AXL,BAD,BCL10,BCL2,BCL6,BST1,BTK,BTLA,CARD11,CAV1,CCDC88B,CCL19,CCL2,CCL21,CCL5,CCR2,CCR7,CD1D,CD2,CD209,CD226,CD24,CD247,CD27,CD274,CD276,CD28,CD320,CD38,CD3D,CD3E,CD3G,CD40,CD46,CD47,CD5,CD55,CD59,CD6,CD74,CD80,CD81,CD83,CD86,CDC42,CDKN1A,CHRNB2,CLCF1,CLECL1,CORO1A,CSK,CTGF,CTLA4,DHPS,DMTN,DNAJA3,DOCK8,DUSP10,EBI3,EFNB1,EFNB2,EFNB3,EPO,EXOSC3,EXOSC6,F2RL1,FADD,FAM19A3,FAM49B,FCER1G,FGF10,FGR,FLOT2,FLT3LG,FOXP3,GAB2,GAS6,GATA2,GATA3,GLI2,GLI3,GPAM,GPR183,GRAP2,GRB2,HAVCR2,HES1,HHLA2,HLX,HMGB1,HSPH1,ICOS,IFNG,IGF1,IGF2,IGFBP2,IGLL1,IGLL5,IHH,IL10,IL12A,IL12B,IL12RB1,IL13,IL15,IL18,IL1B,IL1RL1,IL1RL2,IL2,IL21,IL23A,IL23R,IL33,IL36B,IL4,IL5,IL6,IL6ST,IL7,IL7R,INPP5D,IRS2,ITGAM,ITGB2,ITPKB,JAK2,JAK3,KARS,KIRREL1,KLRK1,LBP,LCK,LEP,LGALS1,LGALS9,LILRB2,LILRB4,LYN,MALT1,MAP3K14,MAP3K7,MAP3K8,MEF2C,MIF,MLH1,MMP14,MSH2,MSH6,MYB,NCK1,NCK2,NCKAP1L,NECTIN2,NFATC2,NPHS1,NR4A3,NSD2,PAK1,PAK2,PAK3,PAXIP1,PCID2,PDCD1,PDCD1LG2,PDGFRB,PDPK1,PDPN,PELI1,PIK3CA,PIK3R1,PIK3R6,PLEK,PNP,PPP2R3C,PRDM1,PRKCQ,PRKCZ,PTAFR,PTPN11,PYCARD,RAC1,RAG1,RARA,RASAL3,RASGRP1,RIF1,RIPK2,RPS3,RPS6KA1,SART1,SASH3,SELENOK,SELP,SHB,SIRPG,SLC39A10,SNX4,SOCS1,SOCS5,SOX15,SPACA3,SPN,SRC,STAP1,STAT6,STX4,STXBP1,SYK,TAC1,TESPA1,TFRC,TGFB1,TGFBR2,THBS1,THY1,TICAM1,TIRAP,TLR4,TLR6,TLR9,TMIGD2,TNFRSF13C,TNFRSF14,TNFRSF4,TNFSF11,TNFSF13,TNFSF13B,TNFSF14,TNFSF9,TNIP2,TRAF2,TRAF6,UNG,VAMP8,VAV1,VAV3,VCAM1,VNN1,VTCN1,WNT3A,WNT5A,XBP1,XCL1,YES1,ZAP70,ZBTB1,ZBTB16,ZMIZ1,ZNF335,ZP3,ZP4	TetrapodAncestor	199.713
GO.Biological.Process	GO:0030278	regulation.of.ossification	107	1.644794e-203	2.124580e-199	1.985589e-201	1.336406e+0	ACVR2A,ACVR2B,ADRB2,AHSG,ANKH,ANO6,AREG,ATP6AP1,ATRAID,AXIN2,BCL2,BCOR,BGLAP,BMP2,BMP4,BMP6,BMP7,BMPR1A,BMPR1B,BMPR2,CCL3,CCR1,CDK6,CEBPA,CEBPB,CEBPD,CHRD,CITED1,CSF1,CTNNB1,CYP27B1,CYR61,DDR2,DDX5,DHRS3,DKK1,EGR2,ENPP1,ESRRA,FAM20C,FBN2,FGF23,FGFR2,FZD9,GDF10,GDF2,GDPD2,GFRA4,GLI3,GNAS,GPM6B,GREM1,HAND2,HDAC4,HDAC7,HDAC8,HGF,HIF1A,ID1,ID3,ID4,IFITM1,IFITM5,IGF1,IGFBP5,IL6,IL6R,IL6ST,INTU,ISG15,JAG1,KL,KREMEN1,KREMEN2,LIMD1,LRP4,LRP5,MAPK1,MAPK14,MAPK3,MATN1,MEF2C,MEN1,MEPE,MGP,MSX2,NBR1,NELL1,NIPBL,NOCT,NOG,NOTCH1,NPPC,OMD,OSR1,OSTN,OXT,P2RX7,PBX1,PDLIM7,PHOSPHO1,PIAS2,PKDCC,PRKACA,PRKD1,PTCH1,PTGER4,PTH,PTK2,PTK2B,RANBP3L,RASSF2,RBPJ,RFLNB,RIOX1,RORB,RUNX2,S1PR1,SEMA4D,SFRP1,SFRP2,SIX2,SKI,SLC8A1,SMAD5,SMOC1,SMURF1,SNAI2,SOST,SOX11,SOX9,SUCO,SUFU,TAC1,TFAP2A,TGFB1,TGFB2,TMEM64,TNF,TNN,TP63,TPH1,TRPM4,TWIST1,TWIST2,TXLNG,UCMA,WNT10B,WNT4,WNT5A,WNT7B,ZBTB16,ZHX3	TetrapodAncestor	198.673
GO.Biological.Process	GO:0043405	regulation.of.MAP.kinase.activity	108	2.200640e-202	2.842567e-198	2.632006e-200	1.275763e+0	ADAM8,ADAM9,ADIPOQ,ADORA1,ADORA2B,ADRA2A,ADRA2B,AGER,AIDA,AJUBA,AKAP13,ALK,APOE,ARAF,ARRB1,AVPI1,BMP2,BMP4,BMP7,BRAF,C1QTNF2,C5,CARTPT,CAV1,CAV3,CBLC,CCL19,CD24,CD300A,CD40,CD74,CD81,CDK1,CRK,CRKL,CSK,CSPG4,CXCR4,DAB2IP,DAXX,DBNL,DKK1,DNAJA1,DRD4,DTNBP1,DUSP1,DUSP10,DUSP16,DUSP18,DUSP19,DUSP2,DUSP21,DUSP22,DUSP3,DUSP6,DUSP7,DUSP8,DUSP9,DVL3,EDN1,EDN3,EGF,EGFR,EIF2AK2,EPGN,EPHA4,EPHB2,ERBB2,ERCC6,ERN1,ERN2,ERP29,EZH2,F2R,FGD2,FGF1,FGF10,FGF18,FGF2,FGFR1,FLT1,FRS2,FZD10,FZD4,FZD5,FZD8,GADD45A,GADD45B,GADD45G,GBA,GH1,GHR,GNG3,GPS1,GRM4,GSTP1,HACD3,HGF,HGS,HMGCR,HRAS,HTR2A,HTR2B,IGF1,IGF1R,IKBKG,IL1B,INAVA,INPP5K,IQGAP1,IQGAP3,IRAK1,IRAK3,ITGA1,JAK2,KARS,KITLG,KRAS,LAMTOR2,LAMTOR3,LAX1,LPAR1,LPAR3,LRRK2,LYN,MADD,MAP2K2,MAP2K3,MAP2K4,MAP2K6,MAP2K7,MAP3K1,MAP3K10,MAP3K11,MAP3K12,MAP3K13,MAP3K14,MAP3K15,MAP3K2,MAP3K21,MAP3K3,MAP3K4,MAP3K5,MAP3K6,MAP3K7,MAP3K7CL,MAP3K8,MAP3K9,MAP4K1,MAP4K3,MAP4K4,MAPK1,MAPK10,MAPK11,MAPK14,MAPK3,MAPK8IP1,MAPK8IP3,MAPKAPK2,MAPKAPK3,MAPKAPK5,MBIP,MIF,MINK1,MOS,MST1R,MUC20,MUL1,NEK10,NF1,NGF,NOD1,NOX4,NRG1,NRK,NTF3,NTRK1,NTRK3,NUP62,P2RX7,PAK1,PAK3,PDCD10,PDE5A,PDE6H,PDGFA,PDGFB,PDGFC,PDGFD,PDGFRB,PEA15,PIK3CG,PIK3R5,PIK3R6,PKN1,PLA2G1B,PLCE1,PLCG1,PPEF2,PRKAA1,PRKCD,PROK1,PROK2,PSEN1,PTK2B,PTPN1,PTPN11,PTPN22,PTPRJ,RAF1,RAP1A,RAPGEF1,RASGRP1,RGS14,RGS2,RGS3,RGS4,RIPK1,RIPK2,ROBO1,ROR2,RPS27A,RPS3,S100A12,SAA1,SASH1,SERPINB3,SFRP1,SFRP2,SHC1,SHC2,SMPD1,SOD1,SORL1,SPAG9,SPRED1,SPRED2,SPRY1,SPRY2,SRC,STK24,STK26,STK38,SYK,TAB1,TAB2,TAB3,TAOK1,TAOK2,TDGF1,TENM1,TGFB1,TGFBR1,THBS1,TIAM1,TLR4,TLR6,TLR9,TMEM189-UBE2V1,TNF,TNFRSF11A,TNFSF11,TNIK,TP73,TPD52L1,TRAF2,TRAF6,TRAF7,TRIB1,TRIB2,TRIB3,TSG101,UBC,UBE2N,UCHL1,VANGL2,VEGFA,WNT5A,WNT7B,ZNF675	TetrapodAncestor	197.546
GO.Biological.Process	GO:0045619	regulation.of.lymphocyte.differentiation	109	5.163605e-202	6.669829e-198	6.119109e-200	1.440177e+0	ABL1,ADA,ADAM8,ANXA1,AP3D1,ATP11C,AXL,BAD,BCL6,BMP4,BRAF,BTK,CAMK4,CARD11,CBFB,CCL19,CD2,CD27,CD28,CD46,CD74,CD80,CD83,CD86,CR1,CTLA4,CYP26B1,DROSHA,DTX1,DUSP10,ERBB2,FANCA,FAS,FBXO7,FLT3LG,FOXJ1,FOXN1,FOXP3,GAS6,GATA3,GLI2,GLI3,HLX,HMGB1,HMGB3,IFNA2,IFNB1,IFNG,IFNL1,IHH,IKZF3,IL12A,IL12B,IL12RB1,IL15,IL18,IL1RL2,IL2,IL23A,IL23R,IL27,IL36B,IL4,IL6,IL7,IL7R,INHA,INHBA,INPP5D,IRF1,IRF4,ITPKB,JAK3,LGALS9,LILRB2,LILRB4,LOXL3,METTL3,MMP14,MYB,NCKAP1L,NDFIP1,NFAM1,NFATC2,NFKBID,PCID2,PGLYRP1,PGLYRP2,PGLYRP3,PIK3R6,PNP,PPP2R3C,PRDM1,PRELID1,PRKCZ,RAG1,RARA,RASGRP1,RC3H1,RIPK2,RNF41,RUNX1,SART1,SASH3,SFRP1,SHB,SLC46A2,SMAD7,SOCS1,SOCS5,SOD1,SOS1,SOX13,SPINK5,SYK,TESPA1,TGFB1,TGFBR2,TLR9,TMEM131L,TNFRSF18,TNFSF18,TNFSF9,VNN1,XBP1,ZAP70,ZBTB1,ZBTB16,ZBTB7B,ZC3H8,ZEB1,ZFP36L1,ZFP36L2,ZMIZ1,ZNF683	TetrapodAncestor	197.176
GO.Biological.Process	GO:0045926	negative.regulation.of.growth	110	6.619089e-201	8.549877e-197	7.772616e-199	1.352244e+0	ACVR1B,ACVRL1,ADAM15,ADIPOR1,ADIPOR2,ADRB2,ADRB3,AGT,AGTR2,ALOX15B,APBB2,ARHGAP4,BCL11A,BCL2,BCL6,BDKRB1,BMP10,BMP4,BMPR2,BST2,BTG1,CAPRIN2,CAV3,CCAR2,CCDC85B,CD36,CDA,CDHR2,CDK5,CDK5R1,CDKN1A,CDKN1B,CDKN2A,CDKN2AIP,CDKN2C,CDKN2D,CRLF3,CRYAB,CTDP1,CYP27B1,DACT3,DCBLD2,DCC,DCUN1D3,DDX3X,DRAXIN,DUSP10,EI24,ENPP1,EPHA7,ESR2,FBP1,FGF13,FGFR3,FLCN,FSTL4,FXN,G6PD,GAL,GDF2,GJA1,GPC3,GREM1,GSK3A,HIF1A,HNF4A,HRG,IFNG,IFRD1,IGFBP5,IL10,IL12B,ING5,INHBA,IRF8,JADE1,JARID2,KCNK2,LBP,LGMN,MAG,MAPK11,MBL2,MEIS1,MPO,MSTN,MSX1,MUL1,NAIF1,NDRG3,NDUFS3,NOG,NOTCH1,NOTCH2,NOV,NPR1,NRP1,OSGIN1,OSGIN2,OSTN,PAK1,PHB,PLAC8,PLXNA3,PML,PNPT1,PPARD,PPARG,PPP1R9B,PPT1,PTCH1,PTEN,PTK2,PTPRJ,PTPRS,RAI1,RBBP7,RBP4,RERG,RNF6,RTN4,RTN4R,SCGB3A1,SEMA3A,SEMA3G,SEMA5A,SERPINE2,SERTAD2,SESN2,SFRP1,SFRP2,SH3BP4,SIPA1,SIRT1,SLC6A4,SLIT2,SLIT3,SMAD4,SMARCA2,SMARCA4,SOCS2,SOX17,SPP1,SQSTM1,ST7L,STC2,STK4,TBX5,TGFB1,TGFB2,TGFBR2,TIRAP,TLL2,TNF,TNR,TP53,TP53TG5,TP73,TRO,ULK2,WFDC1,WNT11,WNT3,WNT3A,WNT5A,WWC1,WWC2,WWC3	TetrapodAncestor	196.068
GO.Biological.Process	GO:0051707	response.to.other.organism	111	6.780695e-200	8.758624e-196	7.890652e-198	1.232638e+0	ABCA1,ABCC2,ABCC8,ABCC9,ABCF3,ABL1,ABR,ACP5,ACTA2,ADAM9,ADAMTS13,ADAMTS5,ADAR,ADARB1,ADGRB1,ADH5,ADH7,AGBL4,AGBL5,AICDA,AKAP8,AKIRIN2,ALAD,ALPL,ANKRD1,ANKRD17,ANXA3,APOB,APOBEC1,APOBEC3A,APOBEC3B,APOBEC3C,APOBEC3D,APOBEC3F,APOBEC3G,APOBEC3H,ARF1,ARG1,ATG16L1,ATG5,ATOX1,AXL,BAD,BAK1,BANF1,BATF2,BATF3,BCL10,BCL2,BCL2L1,BCL2L11,BCL3,BCR,BDKRB1,BECN1,BNIP3,BNIP3L,BPI,BPIFA1,BPIFA2,BPIFB1,BPIFB2,BST2,BTBD17,BTK,C10orf99,C19orf66,C4B,CACTIN,CARD16,CARD17,CASP1,CASP3,CASP8,CASP9,CAV1,CCDC130,CCDC88B,CCL11,CCL19,CCL2,CCL22,CCL3,CCL4,CCL5,CCL8,CCR4,CCR5,CCR7,CCT5,CD14,CD160,CD180,CD1D,CD24,CD27,CD36,CD40,CD47,CD6,CD80,CD86,CD8A,CD96,CDC73,CDK19,CDK4,CDK6,CEBPB,CEBPE,CFL1,CFP,CHGA,CHIA,CHIT1,CHRM2,CHUK,CITED1,CLDN1,CLEC4D,CLEC4E,CLEC6A,CLEC7A,CLU,CMPK2,CNR1,CNR2,COTL1,CPEB1,CPS1,CRCP,CREBZF,CRK,CSF2RB,CSF3,CX3CR1,CXCL1,CXCL10,CXCL11,CXCL13,CXCL16,CXCL2,CXCL3,CXCL5,CXCL6,CXCL8,CXCL9,CXCR4,CYP1A1,CYP1A2,CYP27B1,DAB2IP,DCD,DCN,DDIT4,DDX1,DDX17,DDX21,DDX3X,DDX41,DDX58,DDX60,DEFB110,DEFB112,DEFB113,DEFB115,DEFB124,DEFB131A,DEFB133,DMBT1,DROSHA,DUOX2,DUSP10,EDN1,EDNRB,EEF1G,EIF2AK2,EIF2AK4,ELMOD2,ENSG00000173366,EPHA2,EPO,EPPIN,EPPIN-WFDC6,EPX,ERAP1,EXOSC4,EXOSC5,F2,F2R,F2RL1,FADD,FAM111A,FAM3A,FAS,FASLG,FCER1G,FCN2,FCN3,FER,FGF10,FGFR2,FGR,FMR1,FOS,FOSL1,FOXP3,FUCA2,FZD5,GAPDH,GATA3,GBF1,GCH1,GHSR,GJA1,GNG12,GNLY,GNRH1,GPAM,GSDMD,GSTP1,GTF2F1,GUCY1A3,H2BFS,HAMP,HAVCR2,HCK,HDAC2,HDAC5,HIST2H2BE,HMGA2,HMGB2,HNRNPA0,HNRNPUL1,HP,HPGD,HRAS,HRG,HSF1,HSPB1,IDO1,IFI44,IFI44L,IFIT1,IFIT1B,IFIT2,IFIT3,IFIT5,IFITM1,IFITM2,IFITM3,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNAR1,IFNAR2,IFNB1,IFNE,IFNG,IFNGR1,IFNGR2,IFNK,IFNL1,IFNL2,IFNL3,IFNLR1,IFNW1,IGLL1,IGLL5,IKBKB,IKBKE,IKBKG,IL10,IL10RA,IL10RB,IL12A,IL12B,IL12RB2,IL13,IL17A,IL17RA,IL17RC,IL18,IL18BP,IL1B,IL22RA1,IL23A,IL23R,IL24,IL27,IL27RA,IL31RA,IL33,IL36RN,IL4,IL6,IL6R,ILF3,INAVA,IRAK1,IRAK3,IRF1,IRF2,IRF3,IRF4,IRF7,IRF8,IRF9,IRGM,ISG15,ISG20,ITCH,IVNS1ABP,JAGN1,JAK2,JCHAIN,JUN,JUNB,KCNJ8,KLRK1,KRT6A,LACRT,LBP,LCN2,LGALS8,LGALS9,LILRB2,LITAF,LOXL1,LPO,LRRC70,LTBR,LY96,LYG2,LYN,LYZ,LYZL1,LYZL2,LYZL4,LYZL6,MALT1,MAOB,MAP3K14,MAPK1,MAPK11,MAPK14,MAPK3,MAPK8,MAPKAPK2,MAPKAPK3,MB21D1,MBL2,MEF2C,MGST1,MGST2,MMP12,MPO,MR1,MRC1,MST1R,MTDH,MX1,MX2,NCBP3,NCK1,NFKB1,NFKB2,NFKBIB,NGFR,NLRC4,NLRC5,NLRP1,NLRP10,NLRP6,NLRP7,NLRP9,NOCT,NOD1,NOS2,NOS3,NOTCH1,NPC2,NR1D1,NR1H3,NR1H4,NT5C3A,NUGGC,OAS1,OASL,ODC1,OPRK1,OPRM1,OPTN,OTUD5,P2RX7,PABPN1,PAF1,PALM3,PCBP2,PCK1,PCK2,PDE4B,PDE4D,PDZD11,PELI1,PENK,PF4,PF4V1,PGLYRP1,PGLYRP2,PGLYRP3,PGLYRP4,PI3,PIM2,PLA2G1B,PLA2G2A,PLA2G6,PLAA,PLAC8,PLCG2,PLSCR1,PLSCR4,PMAIP1,PML,POLR3A,POLR3B,POLR3C,POLR3D,POLR3E,POLR3F,POLR3K,PPARD,PPARGC1A,PPBP,PPM1D,PQBP1,PRB3,PRDX3,PRG2,PRKCD,PRKCE,PRKRA,PRPF8,PRSS2,PRSS3,PSMA2,PTAFR,PTGER1,PTGER2,PTGER4,PTGES,PTGFR,PTGIR,PTPN22,PTX3,PYCARD,RAB14,RAB1A,RAB29,RAG2,RARA,RARRES2,RBPJ,REG3A,REG3G,RELA,RELT,REN,RIOK3,RIPK2,RNASEL,RNF5,ROMO1,RPL30,RPS15A,RPS6KA3,RRP1B,RSAD2,RTP4,S100A12,S100A14,S100A7,S100A8,S100A9,SAMHD1,SCARB1,SCGB1A1,SCRIB,SELE,SELP,SEMG1,SEMG2,SERINC3,SERINC5,SERPINB9,SETD2,SHC1,SHPK,SIRT2,SLC11A1,SLC25A6,SLFN11,SLPI,SNCA,SPACA1,SPACA3,SPACA4,SPACA7,SPN,SPON2,SRC,SRR,SSC5D,STAB2,STAP1,STAR,STAT1,STAT2,STMN1,SYK,TAC1,TBK1,TBXA2R,TFPI,TGFB1,TH,THBD,TICAM1,TICAM2,TIMP4,TIRAP,TLR1,TLR2,TLR3,TLR4,TLR5,TLR6,TLR9,TMEM173,TNF,TNFAIP3,TNFRSF10A,TNFRSF10B,TNFRSF10C,TNFRSF10D,TNFRSF11A,TNFRSF11B,TNFRSF14,TNFRSF18,TNFRSF1A,TNFRSF1B,TNFRSF21,TNFRSF25,TNFRSF4,TNFRSF8,TNFRSF9,TNFSF8,TNIP1,TNIP2,TNIP3,TPT1,TRAF6,TREM1,TREM2,TRIB1,TRIM11,TRIM22,TRIM25,TRIM34,TRIM5,TRIM6,TSPAN32,TSPO,UGT1A1,UNC93B1,UPF1,VCAM1,VIL1,VTCN1,WDR35,WFDC12,WIPI2,WNT5A,XBP1,XCL1,XPR1,ZC3H12A,ZC3HAV1,ZFP36	TetrapodAncestor	195.058
GO.Biological.Process	GO:0006954	inflammatory.response	112	4.248274e-199	5.487496e-195	4.899550e-197	1.302465e+0	ABCF1,ACKR2,ADAM8,ADGRE2,ADGRE5,ADORA1,ADORA2A,ADORA3,AFAP1L2,AGER,AGTR2,AHCY,AHSG,AIF1,ALOX15,ALOX5,ANO6,ANXA1,AOAH,AOC3,APOA2,APOL2,APOL3,ATRN,AXL,B4GALT1,BCL6,BDKRB1,BDKRB2,BLNK,BMP2,BMP6,BMPR1B,BTK,C3,C3AR1,C4A,C4B,C5,CAMK1D,CAMK4,CARD18,CASP4,CCL1,CCL11,CCL13,CCL14,CCL15,CCL15-CCL14,CCL16,CCL17,CCL18,CCL19,CCL2,CCL21,CCL22,CCL23,CCL3,CCL3L3,CCL4,CCL4L2,CCL5,CCL7,CCL8,CCR1,CCR2,CCR3,CCR4,CCR5,CCR6,CCR7,CCRL2,CD14,CD163,CD180,CD27,CD40,CD5L,CD6,CD96,CDO1,CEBPB,CHI3L1,CHIA,CHST1,CHST2,CHST4,CHUK,CLEC7A,CNR2,CRHBP,CSF1,CSF1R,CX3CL1,CXCL1,CXCL10,CXCL11,CXCL13,CXCL2,CXCL3,CXCL5,CXCL6,CXCL8,CXCL9,CXCR1,CXCR2,CXCR3,CXCR4,CXCR6,CYBA,CYBB,CYP26B1,DAB2IP,DHX9,ELF3,EPHA2,EPHX2,EPO,F11R,F12,F2,F2R,F2RL1,F3,F8,FAS,FCER1G,FFAR2,FFAR3,FN1,FOS,GAL,GATA3,GGT5,GJA1,GPER1,GPR32,GPR33,GPR68,GSDMD,HAMP,HAVCR2,HCK,HDAC4,HDAC5,HDAC9,HIF1A,HMGB1,HMGB2,HMOX1,HNRNPA0,HP,HSPG2,IDO1,IFNA2,IGFBP4,IKBKB,IKBKG,IL10,IL10RB,IL13,IL15,IL17A,IL17B,IL17C,IL17F,IL17RE,IL18,IL18RAP,IL1A,IL1B,IL1F10,IL1RAP,IL1RL2,IL1RN,IL20RB,IL22,IL23A,IL23R,IL27,IL31RA,IL34,IL36A,IL36B,IL36G,IL36RN,IL37,IL5,IL5RA,IL6,IL6R,IL9,INS,IRGM,ITCH,ITGB2,ITIH4,JAK3,JAM3,KDM6B,KLKB1,KLRG1,KNG1,KRT16,LAT,LBP,LGALS9,LIPA,LOXL3,LTB4R,LTBR,LXN,LY86,LY96,LYN,LYZ,MAP2K3,MAPKAPK2,MBL2,MEFV,MEP1B,MGLL,MIF,MMP25,MS4A2,MYLK3,NAIP,NCR3,NDST1,NFAM1,NFATC3,NFATC4,NFKB1,NFKB2,NFKBID,NFKBIZ,NFRKB,NFX1,NGFR,NLRC4,NLRP1,NLRP10,NLRP2,NLRP6,NLRP9,NMI,NOD1,NOTCH1,NOX4,NPFF,NR1H4,NRROS,NUPR1,OGG1,OLR1,OPRM1,ORM1,ORM2,P2RX7,PARK7,PARP4,PF4,PF4V1,PIK3CA,PIK3CD,PIK3CG,PLA2G2D,PLA2G2E,PLA2G4B,PLAA,PLGRKT,PLP1,PLSCR1,PNMA1,POLB,PPBP,PRCP,PRDX5,PRKCQ,PRKCZ,PRKD1,PROK2,PSTPIP1,PTAFR,PTGDR,PTGES,PTGS1,PTX3,PXK,PYCARD,PYDC2,RAC1,RARRES2,RASGRP1,RBPJ,REG3A,REG3G,REL,RELA,RELB,RELT,RIPK2,RPS6KA4,RPS6KA5,S100A12,S100A8,S100A9,S1PR3,SAA1,SAA2,SAA4,SCG2,SCUBE1,SELE,SELP,SEMA7A,SERPINA1,SERPINA3,SERPINC1,SIGIRR,SIGLEC1,SLC11A1,SMPDL3B,SNAP23,SPHK1,SPP1,SYK,TAC1,TAC4,TBK1,TBXA2R,TFR2,TGFB1,THBS1,THEMIS2,TICAM1,TICAM2,TIRAP,TLR1,TLR10,TLR2,TLR3,TLR4,TLR5,TLR6,TLR9,TMIGD3,TNF,TNFAIP3,TNFAIP6,TNFRSF10A,TNFRSF10B,TNFRSF10C,TNFRSF10D,TNFRSF11A,TNFRSF11B,TNFRSF14,TNFRSF18,TNFRSF1A,TNFRSF1B,TNFRSF21,TNFRSF25,TNFRSF4,TNFRSF8,TNFRSF9,TNIP1,TNIP2,TNIP3,TOLLIP,TPST1,TRIL,TRPV1,TSPAN2,UCN,UGT1A1,VCAM1,VNN1,XCL2,XCR1,ZC3H12A,ZNF580	TetrapodAncestor	194.261
GO.Biological.Process	GO:0006915	apoptotic.process	113	4.726834e-199	6.105651e-195	5.403231e-197	1.181182e+0	ABL1,ACAA2,ACIN1,ACVR1B,ADARB1,ADORA1,ADORA2A,ADRA1A,AEN,AHR,AIFM1,AIFM2,AIFM3,AKT2,ALOX15B,ANXA6,APAF1,APC,API5,APIP,APLP1,APP,APPL1,ARF6,ARL6IP1,ARL6IP5,ARRB1,ASAH2,ATF4,ATG3,ATG4D,ATG5,ATM,ATP2A1,AVP,BABAM2,BAD,BAG1,BAG6,BAK1,BAX,BCAP29,BCAP31,BCL10,BCL2,BCL2A1,BCL2L1,BCL2L10,BCL2L11,BCL2L12,BCL2L13,BCL2L14,BCL2L15,BCL2L2,BCL2L2-PABPN1,BCL3,BCL7B,BCL7C,BCLAF1,BECN1,BFAR,BID,BIK,BIRC2,BIRC3,BIRC5,BIRC6,BLCAP,BLID,BLOC1S2,BMPR2,BMX,BNIP1,BNIP3,BNIP3L,BNIPL,BRAT1,BRCA1,BRSK2,BTK,BUB1,C19orf12,C1D,C1QBP,C3orf38,C6orf120,C8orf4,CAAP1,CADM1,CAMK2A,CAPN10,CARD14,CARD18,CARD6,CASP1,CASP10,CASP14,CASP2,CASP3,CASP4,CASP5,CASP6,CASP8,CASP9,CASR,CAV1,CCAR2,CCK,CD14,CD2,CD24,CD27,CD28,CD38,CD3E,CD40,CD5,CD5L,CD70,CDIP1,CDK1,CDK19,CDK5,CDKN1A,CEBPB,CECR2,CFLAR,CGB3,CGB5,CGB7,CGB8,CHAC1,CHEK1,CHEK2,CHI3L1,CHIA,CHMP3,CIAPIN1,CIB1,CIDEA,CIDEB,CIDEC,CIT,CITED1,CKAP2,CLC,CLPTM1L,CLU,COL4A3,CRADD,CRIP1,CRYAB,CSE1L,CSNK2A1,CSNK2A2,CSRNP1,CTNNBL1,CTSC,CTSH,CTSL,CUL1,CUL2,CUL3,CUL4A,CUL5,CXCR3,CXCR4,CYCS,CYFIP2,CYP1B1,CYR61,DAB2,DAB2IP,DAD1,DAP,DAP3,DAPK1,DAPK2,DAPK3,DAXX,DCC,DDIAS,DDIT4,DDX3X,DDX41,DDX47,DDX5,DEDD,DEDD2,DFFA,DFFB,DHCR24,DIDO1,DIO3,DLC1,DMPK,DNAJA3,DNAJC10,DNASE1,DNASE1L3,DNASE2,DNM1L,DNMT3A,DPEP1,DPF1,DPF2,DRAM1,DRAM2,DUSP22,DYNLL1,DYRK2,E2F1,E2F2,EBAG9,ECSCR,EDA2R,EDAR,EGLN3,EI24,ELMO1,ELMO2,ELMO3,EMC4,ENDOG,EP300,EPB41L3,EPHA2,EPHA7,EPO,ERBB4,ERCC2,ERCC3,ERCC6,ERN1,ERN2,ERO1A,ESPL1,ETV6,EYA2,FADD,FAF1,FAIM2,FAM162A,FAM32A,FAM3B,FAS,FASLG,FASTK,FBXO10,FEM1B,FGF21,FGF4,FGFR2,FGFR3,FHIT,FIS1,FNTA,FOXO1,FZD5,FZD9,G0S2,G2E3,GADD45A,GADD45B,GADD45G,GAPDH,GAS2,GAS6,GCLM,GDF6,GGCT,GHITM,GJA1,GLI3,GLRX2,GML,GNGT1,GPER1,GPR65,GRAMD4,GREM1,GRIK2,GRK5,GSDMA,GSK3A,GSKIP,GSN,GULP1,GZMA,GZMM,H1F0,HAND2,HGNC:18790,HIC1,HIF3A,HINT1,HINT2,HIP1,HIP1R,HIPK1,HIPK2,HMGB1,HMGB2,HMOX1,HRAS,HRK,HSPA5,HTRA2,HTT,IAPP,IER3,IFI27,IFI6,IFIT2,IFNA2,IFNG,IFT57,IKBKE,IKBKG,IL10,IL12A,IL17A,IL19,IL1A,IL1B,IL2,IL24,IL33,IL4,IL6,IL6R,INHBA,INPP5D,IRF1,IRF3,ITCH,ITGAV,ITGB2,ITPR1,JADE1,JAG2,JAK2,JMY,JTB,JUN,KANK2,KCNIP3,KDELR1,KIAA0141,KITLG,KLF11,KLLN,KPNA1,KPNB1,KRCC1,KREMEN1,KRT20,LCN2,LEF1,LGALS1,LGALS12,LGALS13,LGALS14,LGALS16,LGALS7,LGALS7B,LIG4,LRP5,LTBR,LY86,LY96,MADD,MAEL,MAGI3,MAP1S,MAP2K4,MAP2K6,MAP2K7,MAP3K10,MAP3K5,MAP3K7,MAP3K9,MAPK1,MAPK14,MAPK3,MAX,MCM2,MECOM,MEF2A,MEF2C,MEF2D,MEGF10,MELK,METTL21C,MFF,MFN2,MFSD10,MIEN1,MINDY3,MKNK2,MLH1,MLLT11,MRPS30,MSH2,MSH6,MTCH1,MTFP1,MTOR,MUL1,MX1,MYBBP1A,MYC,MYDGF,MZB1,NAE1,NAIF1,NAIP,NBN,NCF1,NCKAP1,NEK6,NF1,NFATC4,NFKB1,NGB,NGF,NGFR,NISCH,NKX2-5,NLRC4,NLRP1,NLRP2,NME3,NOA1,NOC2L,NOD1,NOL3,NOTCH1,NOTCH2,NOX5,NR3C1,NUAK2,NUDT2,NUPR1,OGT,OPA1,OXR1,P2RX4,P2RX7,PACS2,PAEP,PAK1,PAK2,PAK4,PAK5,PANO1,PARP1,PARP2,PAWR,PAX3,PDCD1,PDCD10,PDCD2,PDCD5,PDCD6,PDCD6IP,PDCD7,PDCL3,PDE1B,PDK2,PDPK1,PEA15,PERP,PGAP2,PHLDA1,PHLDA2,PHLPP1,PIDD1,PIGT,PIK3CA,PIK3CG,PIK3R1,PIM1,PIM2,PIM3,PKN1,PLAG1,PLAGL1,PLEKHF1,PLK3,PLSCR1,PMAIP1,PML,POLB,POLR2G,POU4F1,POU4F3,PPARD,PPIF,PPM1F,PPP1R13B,PPP1R13L,PPP1R15A,PPP2CB,PPP2R1B,PPP2R2B,PRDX3,PRDX5,PRELID1,PRKCA,PRKCB,PRKCD,PRKCE,PRKCQ,PRKD1,PRKDC,PRODH,PSEN1,PSMD10,PSME3,PTEN,PTGIS,PTH,PTK2,PTK2B,PTPRH,PYCARD,RABEP1,RAD21,RAF1,RALB,RASSF5,RASSF6,RASSF7,RB1,RBM5,RELT,RFFL,RFK,RHBDD1,RIPK1,RIPK2,RIPK3,RMDN3,RNF130,RNF144B,RNF152,RNF216,RNF34,RNF41,ROBO2,RPS27L,RPS3,RPS6,RPS6KA1,RPS6KA3,RRAGA,RTKN,RTN3,RTN4,RYBP,RYR2,S100A14,S100A8,S100A9,SAP30BP,SART1,SATB1,SCRIB,SELENOK,SEMA3A,SEMA6A,SEPT4,SERPINB9,SFN,SFRP2,SFRP5,SGK1,SGMS1,SGPL1,SGPP1,SH3GLB1,SH3KBP1,SH3RF1,SHARPIN,SHB,SHF,SIAH1,SIAH2,SIRT1,SLC25A6,SLC5A11,SLC5A8,SLIT2,SLIT3,SNCA,SNW1,SOD2,SPI1,SPN,SQSTM1,SRA1,SST,SSTR3,STAT1,STEAP3,STK17A,STK17B,STK24,STK26,STK4,STPG1,SUDS3,TAOK1,TAOK2,TAX1BP1,TBX1,TFAP2B,TFPT,TGFB1,TGFB2,TGFBR1,TGFBR2,THEM4,THOC1,THOC6,TIA1,TIAL1,TIAM1,TICAM1,TICAM2,TIGAR,TIMM50,TLR2,TLR3,TLR4,TM2D1,TMBIM4,TMBIM6,TMEM109,TMEM117,TMEM14A,TMEM173,TMEM214,TMEM219,TNF,TNFAIP1,TNFAIP3,TNFAIP8,TNFRSF10A,TNFRSF10B,TNFRSF10C,TNFRSF10D,TNFRSF11A,TNFRSF11B,TNFRSF12A,TNFRSF14,TNFRSF18,TNFRSF19,TNFRSF1A,TNFRSF1B,TNFRSF21,TNFRSF25,TNFRSF4,TNFRSF8,TNFRSF9,TNFSF10,TNFSF12,TNFSF14,TNFSF15,TNFSF8,TNFSF9,TNIP2,TNS4,TOP2A,TOPAZ1,TOPORS,TP53,TP53AIP1,TP53BP2,TP53INP1,TP63,TP73,TPX2,TRADD,TRAF1,TRAF2,TRAF3,TRAF4,TRAF5,TRAF7,TRAIP,TRIAP1,TRIB3,TRIM35,TRIM39,TSC2,TSPO,UACA,UBE2D3,UNC5A,UNC5B,UNC5C,UNC5D,USP17L3,USP17L30,USP28,USP53,UXT,VIL1,VPS35,WDR92,WWOX,XAF1,XBP1,XIAP,XKR8,XPA,YARS,ZBTB16,ZC3H12A,ZC3H8,ZDHHC16,ZFAND6,ZFP36L1,ZMAT3,ZMAT4,ZNF346,ZNF385A,ZNF385B,ZNF385D,ZNF443,ZNF622,ZPR1,ZSWIM2	TetrapodAncestor	194.214
GO.Biological.Process	GO:0002696	positive.regulation.of.leukocyte.activation	114	1.839500e-198	2.376082e-194	2.084283e-196	1.320091e+0	ADA,ADAM8,ADORA2B,AGER,AIF1,ANXA1,AP1G1,AP3D1,APP,ATAD5,ATP11C,AXL,BAD,BCL10,BCL2,BCL6,BST1,BTK,BTLA,CARD11,CAV1,CCDC88B,CCL19,CCL2,CCL21,CCL5,CCR2,CCR7,CD1D,CD2,CD209,CD226,CD24,CD247,CD27,CD274,CD276,CD28,CD320,CD38,CD3D,CD3E,CD3G,CD40,CD46,CD47,CD5,CD55,CD59,CD6,CD74,CD80,CD81,CD83,CD86,CDC42,CDKN1A,CHRNB2,CLCF1,CLECL1,CORO1A,CSK,CTLA4,DHPS,DNAJA3,DOCK8,DUSP10,EBI3,EFNB1,EFNB2,EFNB3,EPO,EXOSC3,EXOSC6,F2RL1,FADD,FAM19A3,FAM49B,FCER1G,FGF10,FGR,FLOT2,FLT3LG,FOXP3,GAB2,GAS6,GATA2,GATA3,GLI2,GLI3,GPAM,GPR183,GRAP2,GRB2,HAVCR2,HES1,HHLA2,HLX,HMGB1,HSPH1,ICOS,IFNG,IGF1,IGF2,IGFBP2,IGLL1,IGLL5,IHH,IL10,IL12A,IL12B,IL12RB1,IL13,IL15,IL18,IL1B,IL1RL1,IL1RL2,IL2,IL21,IL23A,IL23R,IL33,IL36B,IL4,IL5,IL6,IL6ST,IL7,IL7R,INPP5D,IRS2,ITGAM,ITGB2,ITPKB,JAK3,KARS,KIRREL1,KLRK1,LBP,LCK,LEP,LGALS1,LGALS9,LILRB2,LILRB4,LYN,MALT1,MAP3K14,MAP3K7,MAP3K8,MEF2C,MIF,MLH1,MMP14,MSH2,MSH6,MYB,NCK1,NCK2,NCKAP1L,NECTIN2,NFATC2,NPHS1,NR4A3,NSD2,PAK1,PAK2,PAK3,PAXIP1,PCID2,PDCD1,PDCD1LG2,PDPK1,PELI1,PIK3CA,PIK3R1,PIK3R6,PNP,PPP2R3C,PRDM1,PRKCQ,PRKCZ,PTAFR,PTPN11,PYCARD,RAC1,RAG1,RARA,RASAL3,RASGRP1,RIF1,RIPK2,RPS3,SART1,SASH3,SELENOK,SHB,SIRPG,SLC39A10,SNX4,SOCS1,SOCS5,SPACA3,SPN,SRC,STAP1,STAT6,STX4,STXBP1,SYK,TAC1,TESPA1,TFRC,TGFB1,TGFBR2,THBS1,THY1,TICAM1,TIRAP,TLR4,TLR6,TLR9,TMIGD2,TNFRSF13C,TNFRSF14,TNFRSF4,TNFSF11,TNFSF13,TNFSF13B,TNFSF14,TNFSF9,TNIP2,TRAF2,TRAF6,UNG,VAMP8,VAV1,VAV3,VCAM1,VNN1,VTCN1,WNT3A,WNT5A,XBP1,XCL1,YES1,ZAP70,ZBTB1,ZBTB16,ZMIZ1,ZNF335,ZP3,ZP4	TetrapodAncestor	193.624
GO.Biological.Process	GO:0043207	response.to.external.biotic.stimulus	115	2.621822e-198	3.386607e-194	2.944876e-196	1.230752e+0	ABCA1,ABCB4,ABCC2,ABCC8,ABCC9,ABCF3,ABL1,ABR,ACP5,ACTA2,ADAM9,ADAMTS13,ADAMTS5,ADAR,ADARB1,ADGRB1,ADH5,ADH7,AGBL4,AGBL5,AICDA,AKAP8,AKIRIN2,ALAD,ALPL,ANKRD1,ANKRD17,ANXA3,APOB,APOBEC1,APOBEC3A,APOBEC3B,APOBEC3C,APOBEC3D,APOBEC3F,APOBEC3G,APOBEC3H,ARF1,ARG1,ATG16L1,ATG5,ATOX1,AXL,BAD,BAK1,BANF1,BATF2,BATF3,BCL10,BCL2,BCL2L1,BCL2L11,BCL3,BCR,BDKRB1,BECN1,BNIP3,BNIP3L,BPI,BPIFA1,BPIFA2,BPIFB1,BPIFB2,BST2,BTBD17,BTK,C10orf99,C19orf66,C4B,CACTIN,CARD16,CARD17,CASP1,CASP3,CASP8,CASP9,CAV1,CCDC130,CCDC88B,CCL11,CCL19,CCL2,CCL22,CCL3,CCL4,CCL5,CCL8,CCR4,CCR5,CCR7,CCT5,CD14,CD160,CD180,CD1D,CD24,CD27,CD36,CD40,CD47,CD6,CD80,CD86,CD8A,CD96,CDC73,CDK19,CDK4,CDK6,CEBPB,CEBPE,CFL1,CFP,CHGA,CHIA,CHIT1,CHRM2,CHUK,CITED1,CLDN1,CLEC4D,CLEC4E,CLEC6A,CLEC7A,CLU,CMPK2,CNR1,CNR2,COTL1,CPEB1,CPS1,CRCP,CREBZF,CRK,CSF2RB,CSF3,CX3CR1,CXCL1,CXCL10,CXCL11,CXCL13,CXCL16,CXCL2,CXCL3,CXCL5,CXCL6,CXCL8,CXCL9,CXCR4,CYP1A1,CYP1A2,CYP27B1,DAB2IP,DCD,DCN,DDIT4,DDX1,DDX17,DDX21,DDX3X,DDX41,DDX58,DDX60,DEFB110,DEFB112,DEFB113,DEFB115,DEFB124,DEFB131A,DEFB133,DMBT1,DROSHA,DUOX2,DUSP10,EDN1,EDNRB,EEF1G,EIF2AK2,EIF2AK4,ELMOD2,ENSG00000173366,EPHA2,EPO,EPPIN,EPPIN-WFDC6,EPX,ERAP1,EXOSC4,EXOSC5,F2,F2R,F2RL1,FADD,FAM111A,FAM3A,FAS,FASLG,FCER1G,FCN2,FCN3,FER,FGF10,FGFR2,FGR,FMR1,FOS,FOSL1,FOXP3,FUCA2,FZD5,GAPDH,GATA3,GBF1,GCH1,GHSR,GJA1,GNG12,GNLY,GNRH1,GPAM,GRP,GRPR,GSDMD,GSTP1,GTF2F1,GUCY1A3,H2BFS,HAMP,HAVCR2,HCK,HDAC2,HDAC5,HIST2H2BE,HMGA2,HMGB2,HNRNPA0,HNRNPUL1,HP,HPGD,HRAS,HRG,HSF1,HSPB1,IDO1,IFI44,IFI44L,IFIT1,IFIT1B,IFIT2,IFIT3,IFIT5,IFITM1,IFITM2,IFITM3,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNAR1,IFNAR2,IFNB1,IFNE,IFNG,IFNGR1,IFNGR2,IFNK,IFNL1,IFNL2,IFNL3,IFNLR1,IFNW1,IGLL1,IGLL5,IKBKB,IKBKE,IKBKG,IL10,IL10RA,IL10RB,IL12A,IL12B,IL12RB2,IL13,IL17A,IL17RA,IL17RC,IL18,IL18BP,IL1B,IL22RA1,IL23A,IL23R,IL24,IL27,IL27RA,IL31RA,IL33,IL36RN,IL4,IL6,IL6R,ILF3,INAVA,IRAK1,IRAK3,IRF1,IRF2,IRF3,IRF4,IRF7,IRF8,IRF9,IRGM,ISG15,ISG20,ITCH,IVNS1ABP,JAGN1,JAK2,JCHAIN,JUN,JUNB,KCNJ8,KLRK1,KRT6A,LACRT,LBP,LCN2,LGALS8,LGALS9,LILRB2,LITAF,LOXL1,LPO,LRRC70,LTBR,LY96,LYG2,LYN,LYZ,LYZL1,LYZL2,LYZL4,LYZL6,MALT1,MAOB,MAP3K14,MAPK1,MAPK11,MAPK14,MAPK3,MAPK8,MAPKAPK2,MAPKAPK3,MB21D1,MBL2,MEF2C,MGST1,MGST2,MMP12,MPO,MR1,MRC1,MST1R,MTDH,MX1,MX2,NCBP3,NCK1,NFKB1,NFKB2,NFKBIB,NGFR,NLRC4,NLRC5,NLRP1,NLRP10,NLRP6,NLRP7,NLRP9,NOCT,NOD1,NOS2,NOS3,NOTCH1,NPC2,NR1D1,NR1H3,NR1H4,NT5C3A,NUGGC,OAS1,OASL,ODC1,OPRK1,OPRM1,OPTN,OTUD5,P2RX7,PABPN1,PAF1,PALM3,PCBP2,PCK1,PCK2,PDE4B,PDE4D,PDZD11,PELI1,PENK,PF4,PF4V1,PGLYRP1,PGLYRP2,PGLYRP3,PGLYRP4,PI3,PIM2,PLA2G1B,PLA2G2A,PLA2G6,PLAA,PLAC8,PLCG2,PLSCR1,PLSCR4,PMAIP1,PML,POLR3A,POLR3B,POLR3C,POLR3D,POLR3E,POLR3F,POLR3K,PPARD,PPARGC1A,PPBP,PPM1D,PQBP1,PRB3,PRDX3,PRG2,PRKCD,PRKCE,PRKRA,PRPF8,PRSS2,PRSS3,PSMA2,PTAFR,PTGER1,PTGER2,PTGER4,PTGES,PTGFR,PTGIR,PTPN22,PTX3,PYCARD,RAB14,RAB1A,RAB29,RAG2,RARA,RARRES2,RBPJ,REG3A,REG3G,RELA,RELT,REN,RIOK3,RIPK2,RNASEL,RNF5,ROMO1,RPL30,RPS15A,RPS6KA3,RRP1B,RSAD2,RTP4,S100A12,S100A14,S100A7,S100A8,S100A9,SAMHD1,SCARB1,SCGB1A1,SCRIB,SELE,SELP,SEMG1,SEMG2,SERINC3,SERINC5,SERPINB9,SETD2,SHC1,SHPK,SIRT2,SLC11A1,SLC25A6,SLFN11,SLPI,SNCA,SPACA1,SPACA3,SPACA4,SPACA7,SPN,SPON2,SRC,SRR,SSC5D,STAB2,STAP1,STAR,STAT1,STAT2,STMN1,SYK,TAC1,TBK1,TBXA2R,TFPI,TGFB1,TH,THBD,TICAM1,TICAM2,TIMP4,TIRAP,TLR1,TLR2,TLR3,TLR4,TLR5,TLR6,TLR9,TMEM173,TNF,TNFAIP3,TNFRSF10A,TNFRSF10B,TNFRSF10C,TNFRSF10D,TNFRSF11A,TNFRSF11B,TNFRSF14,TNFRSF18,TNFRSF1A,TNFRSF1B,TNFRSF21,TNFRSF25,TNFRSF4,TNFRSF8,TNFRSF9,TNFSF8,TNIP1,TNIP2,TNIP3,TPT1,TRAF6,TREM1,TREM2,TRIB1,TRIM11,TRIM22,TRIM25,TRIM34,TRIM5,TRIM6,TSPAN32,TSPO,UGT1A1,UNC93B1,UPF1,VCAM1,VIL1,VTCN1,WDR35,WFDC12,WIPI2,WNT5A,XBP1,XCL1,XPR1,ZC3H12A,ZC3HAV1,ZFP36	TetrapodAncestor	193.47
GO.Biological.Process	GO:0060341	regulation.of.cellular.localization	116	2.257822e-196	2.916429e-192	2.514163e-194	1.176587e+0	AAAS,ABCA12,ABCA2,ABHD17A,ABHD17B,ABHD17C,ABL1,ABLIM3,ACSL3,ACSM6,ADCY5,ADCYAP1R1,ADGRE2,ADIPOQ,ADORA2A,ADORA2B,ADRA2A,AGER,AGR2,AGTR2,AKAP6,AKAP8L,AKT2,ANGPT1,ANK2,ANK3,ANO1,AP2M1,APC,APC2,APLNR,APOD,APP,APPL1,AR,ARF1,ARF6,ARHGEF16,ARRB1,ARV1,ASIC1,ASTN2,ATG13,ATG5,ATP13A2,ATP1A2,ATPIF1,AXIN2,B3GAT3,BAD,BAG4,BAK1,BAMBI,BAP1,BARD1,BAX,BCAP31,BCAS3,BCL2,BCL2L1,BCL2L11,BCL3,BDKRB1,BDNF,BECN1,BICD1,BID,BMP4,BMP6,BMP7,BMPR1A,BNIP3L,BRAF,BRSK2,BST2,BTBD9,C12orf4,C1QTNF12,C1QTNF3,C2CD2L,C2CD5,C8orf4,CABP1,CACNA1C,CALCR,CALM1,CALM2,CALM3,CAMK1,CAMK2A,CAMK2D,CAPN10,CASP8,CASQ1,CASQ2,CAV1,CAV3,CCDC22,CCDC88A,CCL19,CCL2,CCNE1,CCNE2,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,CD19,CD27,CD2AP,CD300A,CD36,CDC42,CDCA5,CDH1,CDH2,CDH3,CDK1,CDK16,CDK5,CDK5R1,CDKL2,CDKN1A,CEMIP,CENPQ,CEP250,CEP72,CFTR,CHD7,CHERP,CHMP3,CHP1,CHRM1,CHRNA3,CHRNB4,CIB1,CLDN18,CLIP3,CLTC,CNPY4,CNST,COMMD1,CORO1A,CPLX3,CPLX4,CRIPT,CROCC,CRYAA,CRYAB,CSF3,CSK,CSNK1E,CSNK2A1,CSNK2A2,CTDSPL2,CTNNB1,CXCL10,CXCL11,CXCL9,CYB5R1,CYBA,CYFIP1,DAB2,DAB2IP,DACT1,DACT3,DCLK3,DDRGK1,DDX58,DERL2,DERL3,DHRS7C,DHX9,DIAPH1,DKC1,DLG1,DMAP1,DMD,DMTN,DNAJA1,DNAJC13,DNAJC27,DNM1,DNM1L,DPP10,DRD1,DRD2,DRD3,DRD4,DTNBP1,DTWD2,DTX3L,DVL1,DVL3,DYNC1H1,DYNLL1,DYNLL2,DYRK2,E2F1,ECT2,EDA,EDAR,EDEM1,EDEM2,EFNA5,EGF,EGFR,EIF2AK3,ELMOD1,ENSG00000240045,EPB41,EPB41L2,EPHA2,EPHA3,EPHA5,EPHB2,EPO,ERBB2,ERBB4,EZR,F2,F2R,F2RL3,FAF1,FAM20B,FAM89B,FBXO4,FBXW11,FBXW7,FCER1G,FER,FERMT1,FES,FGF14,FGR,FIS1,FKBP1A,FKBP1B,FLCN,FLNA,FMR1,FOXA2,FOXF1,FZD1,FZD5,FZD7,FZD9,G3BP2,GAB2,GAS1,GAS6,GATA2,GBF1,GCC2,GDI1,GDNF,GLI3,GNAI1,GNAQ,GNL3,GNL3L,GOPC,GOSR1,GPD1L,GPER1,GPHA2,GPLD1,GPM6B,GPR143,GPR68,GREM1,GRIK5,GRIN1,GSK3A,GSN,GSTM2,GTSE1,H2AFY,HAP1,HAX1,HCLS1,HDAC3,HDAC8,HES1,HHAT,HIF1A,HMGCR,HMGN3,HMOX1,HNMT,HNRNPU,HPCA,HPS4,HRC,HSP90AB1,HSPH1,HTRA2,HTT,ICE1,IFI27,IFNG,IFNL3,IGF1,IL10,IL12B,IL13,IL13RA2,IL18,IL18R1,IL1B,IL23A,IL4,IL6,INPP5K,INS,IPO5,IQGAP1,ITGA3,ITGAM,ITGAX,ITGB1,IWS1,JAGN1,JAK2,JPH1,JPH2,JPH3,JPH4,JSRP1,JUP,KALRN,KANK1,KAT7,KCNAB2,KCNB1,KCNE1,KCNJ11,KCNMB4,KCNN3,KDM1A,KEAP1,KHDRBS1,KIF20B,KIF5B,LACRT,LCP1,LDLRAP1,LEP,LEPROT,LEPROTL1,LGALS9,LIF,LILRB4,LITAF,LMNA,LRIG2,LRP1,LRP4,LRP5,LRRC15,LRRK2,LYN,LYPD1,LYPLA1,LZTFL1,MAD1L1,MAGI2,MAP1B,MAP2K2,MAP4K4,MAPK1,MAPK14,MAPK3,MAPK8,MAPT,MBTPS1,MCRS1,MCTP1,MDFI,MDM2,MEF2C,MESD,METTL21C,MFF,MIEF1,MIEF2,MIS18A,MLC1,MPC2,MRGPRE,MSN,MTMR2,MTOR,MX2,MYBPC1,MYBPC3,MYLK2,MYO1C,NAPA,NCBP2,NDC80,NDEL1,NDUFAF2,NECAB2,NEDD4L,NEFH,NF1,NF2,NGFR,NKD2,NLGN1,NLGN3,NMD3,NMT1,NMUR1,NOL3,NOS1,NOV,NPEPPS,NPM1,NPSR1,NPTN,NR1D1,NR1H4,NRG1,NRXN1,NTSR1,NUCB1,NUDT4,NUMB,NUP153,NUP214,NUP54,NUP58,NUP62,NUS1,NUTF2,OAZ1,OAZ2,OGG1,OS9,OTUD7B,OXCT1,P2RX2,P2RX3,P2RX4,P2RX5,P2RX7,PAK1,PARD3,PARD6A,PARK7,PARL,PARP1,PARP10,PARP9,PBLD,PCDH17,PCM1,PCNT,PDCD10,PDCD5,PDE2A,PDE4D,PDPK1,PEMT,PER2,PFN2,PHPT1,PICALM,PID1,PIK3R1,PIK3R2,PIM3,PIN1,PINK1,PINX1,PKD1,PKD2,PKDCC,PKIA,PKIG,PLA2G1B,PLA2G6,PLAA,PLCG1,PLK1,PLK3,PLN,PLS1,PMAIP1,PML,PNKD,POLR1A,POLR3A,PPFIA1,PPP1R12A,PPP1R13B,PPP2R5A,PPP3CA,PPP3CB,PPP3CC,PPP3R1,PRDX1,PREB,PRELID3A,PRKACA,PRKCD,PRKCE,PRKCH,PRKCI,PRKN,PRR5L,PSEN1,PSMB7,PSMD10,PSMD8,PTEN,PTK2B,PTN,PTPN1,PTPN11,PTPN14,PTPN23,PYDC2,RAB11B,RAB11FIP2,RAB11FIP5,RAB21,RAB23,RAB29,RAB3B,RAB3GAP1,RAB5A,RAC2,RALB,RAP1A,RAP1B,RAPGEF3,RASSF5,RB1,RBCK1,RBM22,RBM4,RBPMS,RDX,REEP1,REEP2,REEP6,RER1,RFX6,RHOG,RHOQ,RHOU,RIMS1,RIMS3,RIMS4,RINT1,RIOK2,RIPOR1,RNF139,RNF31,RPL28,RTN4,RUFY3,RUVBL1,RYR2,SAPCD2,SCFD1,SCP2,SEC16B,SEC24B,SELENOI,SELENON,SEMA5A,SEPT5,SESN2,SETD2,SFN,SFRP2,SFRP5,SH3GLB1,SH3TC2,SIAH3,SIDT2,SIRT1,SIRT4,SLC30A1,SLC35D3,SLC51B,SLC8A1,SLC9A3R1,SLC9B2,SMAD4,SMO,SNAI2,SNCA,SNCAIP,SNCG,SNIP1,SNX12,SNX4,SORBS1,SORL1,SOX4,SP100,SPHK1,SPIDR,SPPL3,SQSTM1,SRC,SREBF1,SREBF2,SRI,STARD7,STOM,STX18,STX1A,STX1B,STX3,STX4,STX6,STX7,STXBP1,STXBP2,STXBP4,STYK1,SUFU,SULF2,SVIP,SYBU,SYK,SYN1,SYT11,SYT4,TAX1BP3,TBC1D10C,TBC1D20,TCP1,TDRD12,TENM1,TERF1,TERT,TFDP2,TGFB1,TGFBR1,THOC2,THRA,THY1,TIAM1,TLR2,TLR3,TLR4,TLR9,TM9SF4,TMBIM1,TMBIM6,TMEM110,TMEM173,TMEM27,TMEM30B,TMEM59,TNF,TNFSF14,TNNC1,TNNT2,TOMM7,TONSL,TOR1A,TP53,TP53BP2,TP53INP2,TP63,TP73,TPR,TRAPPC12,TRDN,TREM2,TRIM28,TRIM29,TRIM58,TRIM8,TRIP6,TRPC1,TRPC3,TRPM4,TSGA13,TTL,TXN,U2AF1,U2AF2,UBAC2,UBASH3B,UBE2D3,UBE2G2,UBE2J1,UBE2J2,UBE2L3,UBL5,UBR5,UCP2,UGCG,UHMK1,UNC13A,UNC13B,USP36,VAMP2,VAMP8,VHLL,VIL1,VPS11,VPS35,VPS4A,VSNL1,VTI1B,WAPL,WBP11,WDR46,WDR75,WNK3,WNT3A,WNT5A,WRAP53,WWC1,WWTR1,XCL1,XPO4,XPO5,YIPF5,YOD1,YWHAB,YWHAE,YWHAG,YWHAH,YWHAZ,ZBED3,ZBTB17,ZC3H12A,ZC3H3,ZDHHC8,ZFP36,ZFP36L1,ZIC1,ZMYND8,ZPR1	TetrapodAncestor	191.535
GO.Biological.Process	GO:0009607	response.to.biotic.stimulus	117	2.842428e-193	3.671564e-189	3.138089e-191	1.220401e+0	ABCA1,ABCB4,ABCC2,ABCC8,ABCC9,ABCF3,ABL1,ABR,ACP5,ACTA2,ADAM9,ADAMTS13,ADAMTS5,ADAR,ADARB1,ADGRB1,ADH5,ADH7,AGBL4,AGBL5,AICDA,AKAP8,AKIRIN2,ALAD,ALPL,ANKRD1,ANKRD17,ANXA3,APAF1,APOB,APOBEC1,APOBEC3A,APOBEC3B,APOBEC3C,APOBEC3D,APOBEC3F,APOBEC3G,APOBEC3H,ARF1,ARG1,ATG10,ATG16L1,ATG5,ATOX1,AXL,BAD,BAK1,BANF1,BATF2,BATF3,BCL10,BCL2,BCL2L1,BCL2L11,BCL3,BCR,BDKRB1,BECN1,BNIP3,BNIP3L,BPI,BPIFA1,BPIFA2,BPIFB1,BPIFB2,BST2,BTBD17,BTK,C10orf99,C19orf66,C4B,CACTIN,CARD16,CARD17,CASP1,CASP3,CASP8,CASP9,CAV1,CCDC130,CCDC47,CCDC88B,CCL11,CCL18,CCL19,CCL2,CCL22,CCL3,CCL4,CCL5,CCL8,CCR4,CCR5,CCR7,CCT5,CD14,CD160,CD180,CD1D,CD24,CD27,CD36,CD40,CD47,CD6,CD80,CD86,CD8A,CD96,CDC73,CDK19,CDK4,CDK6,CEBPB,CEBPE,CFL1,CFP,CHGA,CHIA,CHIT1,CHRM2,CHUK,CITED1,CLDN1,CLEC4D,CLEC4E,CLEC6A,CLEC7A,CLU,CMPK2,CNR1,CNR2,COTL1,CPEB1,CPS1,CRCP,CREBZF,CRK,CRTAM,CSF2RB,CSF3,CX3CR1,CXCL1,CXCL10,CXCL11,CXCL13,CXCL16,CXCL2,CXCL3,CXCL5,CXCL6,CXCL8,CXCL9,CXCR4,CYP1A1,CYP1A2,CYP27B1,DAB2IP,DCD,DCN,DDIT4,DDX1,DDX17,DDX21,DDX3X,DDX41,DDX58,DDX60,DEFB110,DEFB112,DEFB113,DEFB115,DEFB124,DEFB131A,DEFB133,DMBT1,DROSHA,DUOX2,DUSP10,EDN1,EDNRB,EEF1G,EIF2AK2,EIF2AK3,EIF2AK4,ELMOD2,EME1,ENSG00000173366,ENSG00000250644,ENSG00000280893,ENSG00000283526,EPHA2,EPO,EPPIN,EPPIN-WFDC6,EPX,ERAP1,EXOSC4,EXOSC5,F2,F2R,F2RL1,FADD,FAM111A,FAM3A,FAS,FASLG,FBXO18,FCER1G,FCN2,FCN3,FER,FGF10,FGFR2,FGR,FMR1,FOS,FOSL1,FOXP3,FUCA2,FZD5,GAPDH,GATA3,GBF1,GCH1,GHSR,GJA1,GNG12,GNLY,GNRH1,GPAM,GRP,GRPR,GSDMD,GSTP1,GTF2F1,GUCY1A3,H2BFS,HAMP,HAVCR2,HCK,HDAC2,HDAC5,HIST2H2BE,HMGA2,HMGB2,HNMT,HNRNPA0,HNRNPUL1,HP,HPGD,HRAS,HRG,HSF1,HSPA5,HSPB1,IDO1,IFI44,IFI44L,IFIT1,IFIT1B,IFIT2,IFIT3,IFIT5,IFITM1,IFITM10,IFITM2,IFITM3,IFITM5,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNAR1,IFNAR2,IFNB1,IFNE,IFNG,IFNGR1,IFNGR2,IFNK,IFNL1,IFNL2,IFNL3,IFNLR1,IFNW1,IGFBPL1,IGLL1,IGLL5,IKBKB,IKBKE,IKBKG,IL10,IL10RA,IL10RB,IL12A,IL12B,IL12RB2,IL13,IL17A,IL17RA,IL17RC,IL18,IL18BP,IL1B,IL22RA1,IL23A,IL23R,IL24,IL27,IL27RA,IL31RA,IL33,IL36RN,IL4,IL6,IL6R,ILF3,INAVA,IRAK1,IRAK3,IRF1,IRF2,IRF3,IRF4,IRF7,IRF8,IRF9,IRGM,ISG15,ISG20,ITCH,IVNS1ABP,JAGN1,JAK2,JCHAIN,JUN,JUNB,KCNJ8,KLRK1,KRT6A,LACRT,LBP,LCN2,LGALS8,LGALS9,LILRB2,LITAF,LOXL1,LPO,LRRC70,LTBR,LY96,LYG2,LYN,LYZ,LYZL1,LYZL2,LYZL4,LYZL6,MALT1,MAOB,MAP3K14,MAPK1,MAPK11,MAPK14,MAPK3,MAPK8,MAPKAPK2,MAPKAPK3,MB21D1,MBL2,MEF2C,MGST1,MGST2,MMP12,MPO,MR1,MRC1,MST1R,MTDH,MUS81,MX1,MX2,NCBP3,NCK1,NFKB1,NFKB2,NFKBIB,NGFR,NLRC4,NLRC5,NLRP1,NLRP10,NLRP6,NLRP7,NLRP9,NOCT,NOD1,NOS2,NOS3,NOTCH1,NPC2,NR1D1,NR1H3,NR1H4,NT5C3A,NUGGC,OAS1,OASL,ODC1,OPRK1,OPRM1,OPTN,OTUD5,P2RX7,PABPN1,PAF1,PALM3,PCBP2,PCK1,PCK2,PDE4B,PDE4D,PDZD11,PELI1,PENK,PF4,PF4V1,PGLYRP1,PGLYRP2,PGLYRP3,PGLYRP4,PI3,PIM2,PLA2G1B,PLA2G2A,PLA2G6,PLAA,PLAC8,PLCG2,PLK5,PLSCR1,PLSCR4,PMAIP1,PML,POLR3A,POLR3B,POLR3C,POLR3D,POLR3E,POLR3F,POLR3K,PPARD,PPARGC1A,PPBP,PPM1D,PPP1R15B,PQBP1,PRB3,PRDX3,PRG2,PRKCD,PRKCE,PRKRA,PRPF8,PRRT2,PRSS2,PRSS3,PSMA2,PTAFR,PTGER1,PTGER2,PTGER4,PTGES,PTGFR,PTGIR,PTPN22,PTX3,PYCARD,RAB14,RAB1A,RAB29,RAG2,RARA,RARRES2,RBMS3,RBPJ,REG3A,REG3G,RELA,RELT,REN,RIOK3,RIPK2,RNASEL,RNF5,ROMO1,RPL30,RPS15A,RPS6KA3,RRP1B,RSAD2,RTP4,S100A12,S100A14,S100A7,S100A8,S100A9,SAMHD1,SCARB1,SCGB1A1,SCRIB,SELE,SELP,SEMG1,SEMG2,SERINC3,SERINC5,SERPINB9,SETD2,SHC1,SHPK,SIRT2,SLC11A1,SLC25A6,SLFN11,SLPI,SLX4,SMC1A,SMO,SNCA,SPACA1,SPACA3,SPACA4,SPACA7,SPN,SPON2,SRC,SRR,SSC5D,STAB2,STAP1,STAR,STAT1,STAT2,STMN1,SYK,SYNDIG1L,TAC1,TBK1,TBXA2R,TFPI,TGFB1,TH,THBD,TICAM1,TICAM2,TIMP4,TIRAP,TLR1,TLR2,TLR3,TLR4,TLR5,TLR6,TLR9,TMCO1,TMEM173,TMEM233,TMEM265,TMEM91,TNF,TNFAIP3,TNFRSF10A,TNFRSF10B,TNFRSF10C,TNFRSF10D,TNFRSF11A,TNFRSF11B,TNFRSF14,TNFRSF18,TNFRSF1A,TNFRSF1B,TNFRSF21,TNFRSF25,TNFRSF4,TNFRSF8,TNFRSF9,TNFSF8,TNIP1,TNIP2,TNIP3,TP53,TPT1,TRAF6,TREM1,TREM2,TRIB1,TRIM11,TRIM22,TRIM25,TRIM34,TRIM5,TRIM6,TSPAN32,TSPO,TUSC5,TXNIP,UGT1A1,UNC93B1,UPF1,VCAM1,VIL1,VTCN1,WDR35,WFDC12,WFS1,WIPI2,WNT5A,XBP1,XCL1,XPR1,ZC3H12A,ZC3HAV1,ZFP36	TetrapodAncestor	188.435
GO.Biological.Process	GO:0045860	positive.regulation.of.protein.kinase.activity	118	2.986156e-193	3.857218e-189	3.268829e-191	1.224139e+0	ABI1,ABL1,ACE,ACSL1,ACVR2B,ADAM8,ADAM9,ADCY2,ADCY3,ADCY4,ADCY5,ADCY8,ADCYAP1,ADIPOQ,ADNP,ADORA1,ADORA2B,ADRA2A,ADRA2B,ADRA2C,ADRB2,AFAP1L2,AGER,AGT,AJUBA,AKAP13,ALK,ALKAL1,ALS2,ANGPT1,ANGPT4,ARAF,ARRB1,ATP2B4,AVPI1,BAK1,BAX,BMP2,BMP4,BRAF,C1QTNF2,C5,C8orf4,CAB39,CACUL1,CALM1,CALM2,CALM3,CAMK1,CAMKK1,CAMKK2,CARD10,CARD14,CARTPT,CCDC88A,CCL19,CCL21,CCL5,CCNB1,CCND1,CCND2,CCND3,CCNH,CCNK,CCNL1,CCNL2,CCNT2,CCR7,CD24,CD40,CD74,CD81,CDC25B,CDC6,CDK1,CDK20,CDK5,CDK5R1,CDK5R2,CDKN1A,CDKN1B,CEMIP,CENPE,CHI3L1,CHRNA3,CIB1,CKS1B,CKS2,CLU,COPS8,CRK,CRKL,CSF1,CSF1R,CSK,CSPG4,CXCR4,CYR61,DAB1,DAB2IP,DAXX,DBF4B,DBNL,DDR2,DDX3X,DGKQ,DKK1,DLG1,DRD2,DRD4,DUSP19,DUSP6,DUSP7,DUSP9,DVL3,DYNAP,ECT2,EDN1,EDN3,EFNA1,EFNA5,EGF,EGFR,EGR1,EIF2AK2,EMP2,EPGN,EPHA4,EPO,ERBB2,ERCC6,EREG,ERN1,ERN2,ERP29,ETAA1,EZH2,F2R,FAM20A,FAM58A,FBXW7,FGD2,FGF1,FGF10,FGF13,FGF18,FGF2,FGFR1,FLT1,FRS2,FZD10,FZD4,FZD5,FZD8,GADD45A,GADD45B,GADD45G,GAS6,GH1,GHR,GNG3,GPRC5B,GREM1,GRM4,GRM5,HACD3,HGF,HMGB1,HRAS,HSP90AB1,HSPA2,HSPA5,HSPH1,HTR2A,HTR2B,IFNG,IGF1,IGF2,IKBKG,IL18,IL1B,INAVA,INS,IQGAP1,IQGAP3,IRAK1,IRGM,ITGA1,JAK2,JTB,KARS,KITLG,KRAS,LAMTOR2,LAMTOR3,LAT,LCP2,LEP,LPAR1,LPAR3,LRP8,LRRK2,MADD,MALT1,MAP2K2,MAP2K3,MAP2K4,MAP2K6,MAP2K7,MAP3K1,MAP3K10,MAP3K11,MAP3K12,MAP3K13,MAP3K14,MAP3K15,MAP3K19,MAP3K2,MAP3K21,MAP3K3,MAP3K4,MAP3K5,MAP3K6,MAP3K7,MAP3K7CL,MAP3K8,MAP3K9,MAP4K1,MAP4K3,MAP4K4,MAPK1,MAPK10,MAPK11,MAPK14,MAPK3,MAPK8IP3,MAPKAP1,MAPKAPK2,MAPKAPK3,MAPKAPK5,MAPRE3,MARK2,MAS1,MIF,MINK1,MLST8,MMD,MMD2,MOS,MRNIP,MST1R,MTCP1,MTOR,MUC20,MUL1,NAB2,NCF1,NCKAP1L,NEK1,NEK10,NEK4,NEURL1,NGF,NKX3-1,NOD1,NOX4,NPM1,NRG1,NRG3,NRK,NTF3,NTRK1,NTRK3,P2RX7,PAK1,PAK2,PAK3,PAK4,PAK5,PARK7,PARP16,PDCD10,PDE5A,PDE6H,PDGFA,PDGFB,PDGFC,PDGFD,PDGFRB,PDPK1,PEA15,PIH1D1,PIK3CA,PIK3CG,PIK3R5,PIK3R6,PINK1,PKD1,PKD2,PKN1,PLA2G1B,PLCE1,PLCG1,PPP2R3C,PRKAA1,PRKACA,PRKACG,PRKAG2,PRKAR1A,PRKAR1B,PRKAR2B,PRKCD,PRKCZ,PRLR,PROK1,PROK2,PROX1,PRR5,PSEN1,PSMD10,PTK2,PTK2B,PTPN1,PTPN11,RAF1,RALB,RAP1A,RAPGEF1,RAPGEF2,RASGRP1,RASSF2,RELN,RGCC,RICTOR,RIPK1,RIPK2,RIPK3,ROBO1,ROR2,RPS27A,RPS3,RPTOR,S100A12,SAA1,SASH1,SBK2,SDC4,SHC1,SHC2,SIRT1,SLC11A1,SLC27A1,SNCA,SNX9,SOD1,SPAG9,SPDYA,SPRY2,SRC,SRCIN1,STAP1,STK24,STK26,STK4,STRADA,STRADB,SYK,TAB1,TAB2,TAB3,TAOK1,TAOK2,TCL1A,TCL1B,TDGF1,TELO2,TENM1,TGFB1,TGFB2,TGFBR1,TGFBR2,THBS1,TIAM1,TIRAP,TLR3,TLR4,TLR6,TLR9,TMEM189-UBE2V1,TNF,TNFRSF10A,TNFRSF10B,TNFRSF11A,TNFSF11,TNFSF15,TNIK,TOM1L1,TP73,TPD52L1,TPX2,TRAF2,TRAF4,TRAF6,TRAF7,TXN,UBC,UBE2N,UCN,UNC119,VANGL2,VAPB,VEGFA,VLDLR,WNK1,WNT11,WNT3A,WNT5A,WNT7B,XRCC5,XRCC6,ZFP91	TetrapodAncestor	188.414
GO.Biological.Process	GO:0030100	regulation.of.endocytosis	119	1.205256e-192	1.556829e-188	1.308260e-190	1.373130e+0	AAK1,ABL1,ABL2,ABR,ACTN4,ADIPOQ,AHI1,AHSG,ALOX15,ANGPT1,ANO6,AP2S1,APELA,APLN,APOA5,APOC1,APOC3,APOE,ARF1,ARF6,ARRB1,ARRB2,ATAD1,ATG3,ATG5,ATXN2,AXL,BCR,BICD1,BIN1,BTBD9,C3,C4A,C4B,C4BPA,C4BPB,CALR,CALY,CAMK1D,CAV1,CAV3,CBL,CBLL1,CCL19,CCL2,CCL21,CD14,CD2AP,CD300A,CD300LF,CD36,CD47,CD63,CDH13,CLIP3,CSK,CYBA,DAB2,DKK1,DLG4,DLL1,DNM1L,DNM2,DOCK2,DRD2,EEF2K,EGF,EHD4,EPHA3,F2RL1,FCER1G,FGR,FLOT1,FMR1,GAS6,GATA2,GPC3,GREM1,HCK,HIP1,HIP1R,HIST1H1A,HMGB1,HNRNPK,IL1B,ITGA2,ITGAV,LDLR,LDLRAP1,LGALS3,LMAN2,LRP1,LRPAP1,LRRTM1,LRRTM2,LRSAM1,MAGI2,MBL2,MCTP1,MERTK,MFGE8,MIB1,MTMR2,MYO18A,NCKAP1L,NECAB2,NEDD4L,NLGN1,NR1H2,NR1H3,NTF3,OPHN1,PACSIN2,PACSIN3,PICALM,PICK1,PLCG2,PPARG,PPP3CA,PPT1,PRKCG,PRKD1,PROM2,PTEN,PTPN1,PTX3,PYCARD,RAB14,RAB17,RAB21,RAB27A,RAB4A,RAB4B,RAB5A,RAB5B,RAC1,RAP1A,RAPGEF1,RIT2,RSPO1,RUBCN,RUFY1,RUFY2,SCAMP5,SCARB1,SCYL2,SDCBP,SELE,SFRP4,SGIP1,SH3GL2,SLC11A1,SMAP1,SNAP91,SNCA,SNX12,SNX17,SPACA3,SRC,STAP1,STON2,STX1B,SYK,SYT11,SYT4,SYT7,TBC1D5,TF,TFR2,TGFB1,TLR2,TNF,TNK2,TOR1A,TSC2,TSG101,TUB,TULP1,UNC119,VEGFA,VPS28,VTN,WNT3A,WNT5A,ZFYVE16	TetrapodAncestor	187.808
GO.Biological.Process	GO:0050878	regulation.of.body.fluid.levels	120	3.283912e-192	4.241829e-188	3.534858e-190	1.249239e+0	A2M,ABAT,ABCA12,ABCB4,ADA,ADAMTS13,ADAMTS18,ADCY2,ADCY3,ADCY4,ADCY5,ADCY8,ADORA1,ADORA2A,ADRA2A,ADRA2B,ADRA2C,AGR2,AK3,AKAP1,AKAP10,AKR1B1,ANO6,ANXA5,APLN,APLNR,APOE,APOH,AQP1,AQP2,AQP3,AQP4,AQP5,ARRB1,ARRB2,ASIC2,ATG5,ATP7B,AVP,AVPR2,AXL,BLOC1S3,BLOC1S4,BPIFA1,BTC,C11orf63,C1GALT1C1,C1QBP,C1QTNF1,C4BPB,CAPZA2,CAPZB,CARMIL1,CAV1,CCND1,CD34,CD36,CD40,CD59,CD9,CDC42,CDO1,CEL,CFTR,CHRM1,CHRM3,CLDN1,CLDN4,CLEC1B,CLEC4M,COL1A1,COL1A2,COL3A1,COPA,CPB2,CREB1,CYBA,CYP11B2,CYP26B1,CYP4A11,DCANP1,DDR1,DGKA,DGKB,DGKD,DGKE,DGKG,DGKI,DGKK,DGKQ,DGKZ,DHODH,DMTN,DOCK11,DOCK6,DOCK8,DOCK9,DRD2,DTNBP1,EDN1,EDNRB,EHD1,EHD2,EHD3,EMP2,ENPP4,ENSG00000255439,ENSG00000259753,ENTPD2,EPHB2,ERBB4,F10,F11,F12,F13A1,F13B,F2,F2R,F2RL1,F2RL3,F3,F5,F7,F8,F9,FAM46A,FBLN1,FCER1G,FERMT3,FGF10,FGG,FIBP,FLG,FLG2,FLI1,FLNA,FOXA2,FZD6,GAS6,GATA2,GATA3,GATA4,GATA5,GATA6,GBA,GGCX,GHRHR,GJA1,GNA11,GNA12,GNA13,GNA14,GNA15,GNAQ,GNAS,GNG2,GP1BA,GP1BB,GP5,GP6,GP9,GPAT4,GRHL3,GUCA1B,GUCA2B,H3F3A,HAS2,HBB,HBD,HBE1,HBG1,HBG2,HDAC1,HDAC2,HEG1,HIF1A,HIST1H3H,HIST1H3I,HIST1H3J,HIST2H3A,HIST2H3C,HIST2H3D,HMG20B,HNF4A,HPS4,HPS5,HPSE,HRG,HRNR,HSD11B2,HSPB1,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNB1,IL6,INPP5K,IRF1,IRF2,ITGA2,ITGA2B,ITPK1,ITPR1,ITPR2,ITPR3,JAK2,JMJD1C,KALRN,KDF1,KDM1A,KLKB1,KNG1,KRT1,KRT16,LACRT,LAT,LBH,LCK,LCP2,LMAN1,LYN,MAFF,MAFG,MAPK1,MAPK3,MERTK,MET,METAP1,MFN2,MICAL1,MMRN1,MYH9,MYL9,MYO5B,NCOA1,NEURL1,NEUROG1,NLRP6,NME1,NOS3,NPR1,NPR3,NR1H2,NR1H3,OPRK1,OPRL1,OXT,OXTR,P2RX2,P2RX3,P2RX4,P2RX5,P2RX6,P2RX7,P2RY1,P2RY2,PABPC4,PAFAH2,PAM,PAPSS2,PARP9,PDGFA,PDGFB,PDGFC,PDGFD,PDPK1,PDPN,PDSS2,PF4,PF4V1,PHF21A,PIK3CA,PIK3CD,PIK3CG,PIK3R1,PIK3R5,PIK3R6,PLAT,PLAU,PLCG2,PLEK,PLG,PLSCR1,PRCP,PRKACA,PRKACG,PRKAR1A,PRKAR1B,PRKAR2B,PRKCA,PRKCB,PRKCD,PRKCE,PRKCG,PRKCH,PRKCQ,PRKG1,PRL,PRLR,PROC,PROCR,PROS1,PROZ,PTPN11,PTPRO,RAB11FIP2,RAB27A,RAB5A,RAC1,RAC2,RAD51B,RAD51C,RAF1,RAP2B,RBSN,RCOR1,RHOG,SAA1,SCARA5,SCNN1A,SCNN1B,SCNN1G,SCT,SCUBE1,SELP,SERPINA1,SERPINA10,SERPINA5,SERPINB2,SERPINC1,SERPIND1,SERPINE2,SERPING1,SFN,SH2B1,SH2B2,SH2B3,SLC22A2,SLC22A4,SLC29A1,SLC4A5,SLC6A3,SLC7A11,SOCS2,SRC,SRF,STAB2,STMN1,STXBP1,STXBP5,SYK,SYTL2,TAC1,TAC4,TBXA2R,TC2N,TEC,TFAP2B,TFPI,TFPI2,THBD,THBS1,TIFAB,TLN1,TLR4,TMEM79,TMPRSS6,TP63,TRPC3,TRPC6,TRPC7,TRPV5,TSPAN32,TSPAN8,TXK,TYRO3,UBASH3B,UCN,UMPS,UPRT,USF1,USF2,UTS2,UTS2R,VAMP8,VAV1,VAV2,VAV3,VCL,VDR,VEGFA,VIP,VKORC1,VPS33B,VPS45,VTN,VWF,WFS1,WNK1,WNK3,WNK4,WNT3A,XBP1,XDH,YWHAZ,ZFPM1,ZFPM2,ZNF385A	TetrapodAncestor	187.372
GO.Biological.Process	GO:0071219	cellular.response.to.molecule.of.bacterial.origin	121	3.285657e-192	4.244083e-188	3.507507e-190	1.483643e+0	ABCA1,ABCC2,ABL1,ADAM9,ADAMTS13,AICDA,AKAP8,ANKRD1,ARG1,AXL,BCR,CACTIN,CARD16,CARD17,CASP1,CCL2,CCL3,CCL5,CCR5,CD14,CD180,CD36,CD40,CD6,CD80,CD86,CDC73,CDK19,CDK4,CEBPB,CEBPE,CMPK2,CPEB1,CSF3,CX3CR1,CXCL10,CXCL16,CXCL6,CXCL8,DAB2IP,EDNRB,FZD5,GHSR,GSTP1,HAMP,HAVCR2,HCK,HDAC5,HMGB2,HSF1,IFNG,IL10,IL12A,IL12B,IL18,IL1B,IL24,IL6,IRAK1,IRF3,IRF8,IRGM,KLRK1,LBP,LCN2,LILRB2,LITAF,LY96,LYN,MAPK1,MAPK14,MAPK3,MAPK8,MEF2C,MRC1,MTDH,NFKB1,NFKBIB,NLRP7,NOS2,NOS3,NR1D1,NR1H3,NR1H4,NUGGC,OPRK1,PABPN1,PAF1,PDE4B,PDE4D,PLAA,PLSCR4,PPARD,PPARGC1A,PRKCE,PRPF8,PTAFR,PTPN22,PYCARD,RARA,RELA,RIPK2,SCARB1,SHPK,SIRT2,SPON2,SRC,STAP1,STAR,TBXA2R,TFPI,TGFB1,TICAM1,TICAM2,TIRAP,TLR1,TLR2,TLR4,TLR5,TLR6,TNF,TNFAIP3,TNFRSF1B,TNIP1,TNIP2,TNIP3,TRAF6,TREM2,TSPO,UPF1,WNT5A,XBP1,ZC3H12A,ZFP36	TetrapodAncestor	187.372
GO.Biological.Process	GO:1902107	positive.regulation.of.leukocyte.differentiation	122	4.158090e-192	5.371005e-188	4.402463e-190	1.438462e+0	ACIN1,ADA,ADAM8,AGER,ANXA1,AP3D1,ATP11C,ATP6AP1,AXL,BAD,BCL6,BTK,CA2,CASP8,CCL19,CCR1,CD101,CD27,CD46,CD74,CD80,CD83,CD86,CREB1,CSF1,DUSP10,FADD,FLT3LG,FOS,FOXP3,GAS6,GATA3,GLI2,GLI3,GNAS,GPR68,HAX1,HCLS1,HLX,HMGB1,IFNG,IHH,IL12A,IL12B,IL12RB1,IL15,IL17A,IL18,IL1RL2,IL2,IL20,IL23A,IL23R,IL34,IL36B,IL4,IL5,IL6,IL7,IL7R,INPP5D,ITPKB,JUN,KITLG,KLF10,LEF1,LGALS9,LIF,LILRB2,LILRB4,MMP14,MYB,NCKAP1L,OCSTAMP,PCID2,PF4,PIK3R6,PNP,POU4F1,PPARGC1B,PPP2R3C,PRDM1,PRKCA,PRKCZ,RAG1,RARA,RASGRP1,RB1,RIPK1,RIPK2,ROR2,RUNX1,SART1,SASH3,SHB,SLC9B2,SOCS1,SOCS5,SYK,TESC,TESPA1,TGFB1,TGFBR2,TMEM64,TNF,TNFSF11,TNFSF9,TRAF6,TRIB1,VNN1,XBP1,ZAP70,ZBTB1,ZBTB16,ZFP36L1,ZMIZ1	TetrapodAncestor	187.27
GO.Biological.Process	GO:0001525	angiogenesis	123	5.449042e-192	7.038528e-188	5.722380e-190	1.278027e+0	AAMP,ACKR3,ACVRL1,ADAM15,ADAM8,ADGRA2,ADGRG1,ADIPOR2,ADM2,AGGF1,ANGPT1,ANGPT2,ANGPT4,ANGPTL4,ANPEP,APOD,APOLD1,ARHGAP22,ARHGAP24,ATPIF1,B4GALT1,BCAS3,BMP4,BMPER,C1GALT1,CALCRL,CAV1,CCBE1,CCL2,CD34,CDC42,CDH13,CIB1,COL15A1,COL18A1,COL8A1,COL8A2,CSPG4,CTGF,CTNNB1,CX3CL1,CXCL8,CXCR3,CYP1B1,CYR61,DAB2IP,DLL1,DLL4,E2F7,E2F8,ECSCR,EDN1,EFNA1,EFNB2,EGF,EGFL7,EGR3,EIF2AK3,ELK3,ENG,ENPEP,ENSG00000259753,EPAS1,EPGN,EPHA1,EPHA2,EPHB1,EPHB2,EPHB3,EPHB4,ERAP1,EREG,ESM1,ETS1,FGF1,FGF10,FGF18,FGF2,FGF6,FGF9,FGFR1,FGFR2,FLT1,FLT4,FMNL3,FN1,FOXC2,FZD5,FZD8,GAB1,GBX2,GDF2,GNA13,GPLD1,GPR4,GREM1,HAND1,HAND2,HEY1,HIF1A,HIF3A,HMOX1,HPSE,HRG,HS6ST1,HSPG2,ID1,IHH,IL18,ITGA5,ITGAV,ITGB1,JAG1,JAM3,JMJD6,JUN,KLF5,KRIT1,LAMA5,LEF1,LEMD3,LEP,LEPR,LOXL2,MAPK14,MCAM,MEIS1,MEOX2,MFGE8,MMP14,MMP19,MMRN2,MYDGF,MYH9,NAA15,NCL,NDNF,NFATC4,NOS3,NOTCH1,NOTCH3,NOTCH4,NOV,NOX5,NR4A1,NRP1,NRP2,NUS1,OTULIN,OVOL2,PDCD10,PDCD6,PDCL3,PDGFA,PDGFRB,PIK3CA,PIK3CG,PIK3R6,PITX2,PKNOX1,PLCD3,PLXDC1,PLXND1,PRCP,PRKCA,PRKD1,PRKD2,PRKX,PROK1,PROK2,PTEN,PTK2,PTK2B,PTPRB,RAMP1,RAMP2,RAPGEF3,RASIP1,RBPJ,RNF213,ROBO1,ROBO4,RSPO3,S100A7,S1PR1,SAT1,SCG2,SEMA3E,SEMA4A,SEMA5A,SETD2,SFRP2,SH2D2A,SHB,SHC1,SIRT1,SLC12A6,SLIT2,SOX17,SOX18,SRF,SRPK2,SRPX2,STAB2,STK4,SYK,TAL1,TBX1,TBX20,TCF21,TDGF1,TEK,TGFB2,TGFBI,TGFBR1,TGFBR2,THBS1,THSD7A,THY1,TIE1,TMEM100,TMEM2,TMPRSS6,TNFRSF12A,TNFSF12,TSPAN12,TYMP,UBP1,UNC5B,VASH1,VAV2,VAV3,VEGFA,VEGFB,VEGFC,VEGFD,VEZF1,VHLL,WARS,WASF2,WNT7A,XBP1,ZC3H12A	TetrapodAncestor	187.153
GO.Biological.Process	GO:0048729	tissue.morphogenesis	124	2.757045e-189	3.561275e-185	2.871996e-187	1.193291e+0	ABL1,ACTA2,ACTG2,ACVRL1,ADAMTS16,ADARB1,AHI1,AJUBA,ALDH1A3,ALX1,ANKRD1,APAF1,AR,AREG,ARHGAP12,ARHGAP35,ARID1A,ARL13B,ARTN,ASTN2,B4GALT1,BBS4,BBS7,BCL10,BCL2,BMP10,BMP2,BMP4,BMP5,BMP7,BMPR1A,BMPR2,BTRC,C2CD3,C5orf42,CA2,CA9,CAMSAP3,CARMIL2,CASR,CCDC103,CCDC40,CCL11,CCM2,CCM2L,CD44,CDC42,CELSR1,CFL1,CHD7,CHRD,CITED1,COBL,COL11A1,COL3A1,COL5A1,CRB2,CRYGS,CSF1,CSF1R,CSNK2B,CTNNB1,CTSH,CTSZ,CYR61,DCHS1,DDR1,DEAF1,DKK1,DLC1,DLG1,DLG3,DLG5,DLL1,DLL4,DNAAF1,DSP,DVL1,DVL3,EDN1,EFNB2,EGF,EGFR,EGLN1,ENG,EOMES,EPB41L5,EPHA2,EPHA4,EPHA7,ESR1,ESRP2,EXOC4,EXT2,EYA1,EYA2,FAT4,FEM1B,FGF1,FGF10,FGF2,FGF7,FGFR1,FGFR2,FKBP1A,FLNA,FLRT3,FMN1,FOXA1,FOXC1,FOXC2,FOXE1,FOXF1,FOXF2,FOXH1,FOXL1,FOXN1,FOXN4,FOXQ1,FRAS1,FREM2,FRS2,FUZ,FZD1,FZD2,FZD3,FZD5,FZD6,GATA3,GATA4,GBX2,GCNT3,GCNT4,GDF2,GDNF,GLI2,GLI3,GNA13,GORAB,GPC3,GRB2,GREM1,GRHL2,GRHL3,GRSF1,GZF1,HAND1,HAND2,HBEGF,HEG1,HES1,HES5,HESX1,HEY1,HEY2,HEYL,HHEX,HIF1A,HMGA2,HNF1B,ID4,IFT172,IFT20,IFT52,IFT57,IGFBP5,IHH,IL10,IL6,INHBA,INTU,ISL1,ITGA2,ITGA3,ITGA5,ITGA8,ITGB1,ITGB4,JAG1,JAG2,KDF1,KDM2B,KDM5B,KDM6A,KDM6B,KIF20B,KIF26B,KLF4,KLHL3,KRAS,KRT16,KRT17,KRT25,KRT27,KRT6A,KRT71,LAMA5,LBX1,LEF1,LGR4,LGR5,LHX1,LHX2,LIN7C,LMO4,LRP5,LRP6,LUZP1,MATN1,MDM2,MEF2C,MEGF8,MESP1,MESP2,MET,MIB1,MKKS,MKS1,MMP12,MMP14,MSGN1,MSN,MSX1,MSX2,MTHFD1,MTHFD1L,MTSS1,MYBPC3,MYC,MYCN,MYF6,MYH6,MYH7,MYL3,MYLK,MYLK2,MYO9A,NDRG4,NF2,NFATC4,NKX2-5,NKX3-1,NOG,NOTCH1,NOTCH4,NOTO,NPHP3,NR4A3,NRG1,NRP1,OPHN1,OSR1,OVOL2,PAFAH1B1,PAK1,PAX2,PAX7,PAX8,PBX1,PCDH8,PDCD10,PDPN,PFN1,PGR,PHACTR4,PITX2,PKD1,PKD2,PKP2,PLET1,PLXNA1,PLXNB2,PLXND1,PML,PODXL,POFUT2,POU4F1,PRICKLE1,PRKACA,PRKAR1A,PRKD2,PRKX,PROX1,PSEN1,PTCD2,PTCH1,PTK7,RALA,RARA,RARG,RASIP1,RBPJ,RDH10,RET,RHOC,RIPK4,RSPO2,RSPO3,RXRA,RYR2,S1PR1,SCRIB,SCX,SDC4,SEC24B,SEMA3A,SEMA3C,SEMA3E,SEMA4C,SERPINB5,SETD2,SETDB2,SFRP1,SFRP2,SH3BP1,SHOX2,SHROOM3,SIRT6,SIX2,SKI,SLC9A3R1,SLIT2,SMAD2,SMAD4,SMAD7,SMO,SNAI1,SNAI2,SOCS3,SOS1,SOSTDC1,SOX10,SOX11,SOX17,SOX18,SOX4,SOX8,SOX9,SPINT1,SPRY1,SPRY2,SRC,SRF,ST14,STARD13,STC1,STIL,STK4,SUFU,SYNE4,T,TACSTD2,TAL1,TBX1,TBX2,TBX20,TBX3,TBX5,TBX6,TCF15,TCF21,TEAD2,TFAP2A,TGFB1,TGFB1I1,TGFB2,TGFBR1,TGFBR2,TGM2,TGM3,TIMELESS,TLX2,TMED2,TMEFF2,TMEM100,TMEM79,TNC,TNNC1,TNNI3,TNNT2,TOR1A,TP63,TRAF3IP1,TRAF6,TRIM28,TRIM71,TSC2,TTN,TULP3,TWIST1,TXNRD1,VANGL2,VASP,VCL,VDR,VEGFA,VEGFC,VPS52,WDR1,WLS,WNK4,WNT1,WNT10A,WNT11,WNT16,WNT3,WNT3A,WNT4,WNT5A,WNT6,WNT7A,WNT7B,WNT9B,ZFPM1,ZFPM2,ZIC3	TetrapodAncestor	184.448
GO.Biological.Process	GO:0033674	positive.regulation.of.kinase.activity	125	5.965168e-189	7.705208e-185	6.164166e-187	1.214697e+0	ABI1,ABL1,ACE,ACSL1,ACVR2B,ADAM8,ADAM9,ADCY2,ADCY3,ADCY4,ADCY5,ADCY8,ADCYAP1,ADIPOQ,ADNP,ADORA1,ADORA2B,ADRA2A,ADRA2B,ADRA2C,ADRB2,AFAP1L2,AGER,AGT,AJUBA,AKAP13,ALK,ALKAL1,ALS2,AMBRA1,ANGPT1,ANGPT4,ARAF,ARRB1,ATG14,ATP2B4,AVPI1,BAD,BAK1,BAX,BMP2,BMP4,BRAF,C1QTNF2,C5,C8orf4,CAB39,CACUL1,CALM1,CALM2,CALM3,CAMK1,CAMKK1,CAMKK2,CARD10,CARD14,CARTPT,CCDC88A,CCL19,CCL21,CCL5,CCNB1,CCND1,CCND2,CCND3,CCNH,CCNK,CCNL1,CCNL2,CCNT2,CCR7,CD24,CD40,CD74,CD81,CDC25B,CDC42,CDC6,CDK1,CDK20,CDK5,CDK5R1,CDK5R2,CDKN1A,CDKN1B,CEMIP,CENPE,CHI3L1,CHRNA3,CIB1,CKS1B,CKS2,CLU,COPS8,CRK,CRKL,CSF1,CSF1R,CSK,CSPG4,CXCR4,CYR61,DAB1,DAB2IP,DAXX,DBF4B,DBNL,DDR2,DDX3X,DGKQ,DKK1,DLG1,DRD2,DRD4,DSTYK,DUSP19,DUSP6,DUSP7,DUSP9,DVL3,DYNAP,ECT2,EDN1,EDN3,EFNA1,EFNA5,EGF,EGFR,EGR1,EIF2AK2,EMP2,EPGN,EPHA4,EPHA8,EPO,ERBB2,ERCC6,EREG,ERN1,ERN2,ERP29,ETAA1,EZH2,F2,F2R,FAM20A,FAM58A,FBXW7,FGD2,FGF1,FGF10,FGF13,FGF18,FGF2,FGFR1,FGFR3,FGR,FLT1,FRS2,FZD10,FZD4,FZD5,FZD8,GADD45A,GADD45B,GADD45G,GAS6,GCN1,GH1,GHR,GNG3,GPRC5B,GREM1,GRM4,GRM5,HACD3,HGF,HMGB1,HRAS,HSP90AB1,HSPA2,HSPA5,HSPH1,HTR2A,HTR2B,IFNG,IGF1,IGF2,IKBKG,IL18,IL1B,INAVA,INS,IQGAP1,IQGAP3,IRAK1,IRGM,IRS1,ITGA1,JAK2,JTB,KARS,KITLG,KRAS,LAMTOR2,LAMTOR3,LAT,LCP2,LEP,LMO4,LPAR1,LPAR3,LRP8,LRRK2,LYN,MADD,MALT1,MAP2K2,MAP2K3,MAP2K4,MAP2K6,MAP2K7,MAP3K1,MAP3K10,MAP3K11,MAP3K12,MAP3K13,MAP3K14,MAP3K15,MAP3K19,MAP3K2,MAP3K21,MAP3K3,MAP3K4,MAP3K5,MAP3K6,MAP3K7,MAP3K7CL,MAP3K8,MAP3K9,MAP4K1,MAP4K3,MAP4K4,MAPK1,MAPK10,MAPK11,MAPK14,MAPK3,MAPK8IP3,MAPKAP1,MAPKAPK2,MAPKAPK3,MAPKAPK5,MAPRE3,MAPT,MARK2,MAS1,MIF,MINK1,MLST8,MMD,MMD2,MOS,MRE11,MRNIP,MST1R,MTCP1,MTOR,MUC20,MUL1,NAB2,NBN,NCF1,NCKAP1L,NEK1,NEK10,NEK4,NEURL1,NGF,NKX3-1,NOD1,NOX4,NPM1,NRG1,NRG3,NRK,NTF3,NTRK1,NTRK3,P2RX7,PAK1,PAK2,PAK3,PAK4,PAK5,PARK7,PARP16,PDCD10,PDE5A,PDE6H,PDGFA,PDGFB,PDGFC,PDGFD,PDGFRB,PDPK1,PEA15,PFKFB1,PFKFB2,PIFO,PIH1D1,PIK3CA,PIK3CG,PIK3R5,PIK3R6,PINK1,PKD1,PKD2,PKN1,PLA2G1B,PLCE1,PLCG1,PPP2R3C,PRKAA1,PRKACA,PRKACG,PRKAG2,PRKAR1A,PRKAR1B,PRKAR2B,PRKCD,PRKCZ,PRKD1,PRLR,PROK1,PROK2,PROX1,PRR5,PSEN1,PSMD10,PTK2,PTK2B,PTPN1,PTPN11,RAD50,RAF1,RALB,RANBP2,RAP1A,RAPGEF1,RAPGEF2,RASGRP1,RASSF2,RELN,RGCC,RICTOR,RIPK1,RIPK2,RIPK3,ROBO1,ROR2,RPS27A,RPS3,RPTOR,S100A12,SAA1,SASH1,SBK2,SDC4,SHC1,SHC2,SIRT1,SLC11A1,SLC27A1,SNCA,SNX9,SOD1,SPAG9,SPDYA,SPRY2,SRC,SRCIN1,STAP1,STK24,STK26,STK4,STRADA,STRADB,SYK,TAB1,TAB2,TAB3,TAOK1,TAOK2,TCL1A,TCL1B,TDGF1,TEK,TELO2,TENM1,TGFB1,TGFB2,TGFBR1,TGFBR2,THBS1,TIAM1,TIGAR,TIRAP,TLR3,TLR4,TLR6,TLR9,TMEM189-UBE2V1,TNF,TNFAIP8L3,TNFRSF10A,TNFRSF10B,TNFRSF11A,TNFSF11,TNFSF15,TNIK,TOM1L1,TP73,TPD52L1,TPX2,TRAF2,TRAF4,TRAF6,TRAF7,TXN,UBC,UBE2N,UCN,UNC119,VANGL2,VAPB,VAV2,VAV3,VEGFA,VLDLR,WNK1,WNT11,WNT3A,WNT5A,WNT7B,XRCC5,XRCC6,ZFP91,ZNF16,ZNF622	TetrapodAncestor	184.113
GO.Biological.Process	GO:0048844	artery.morphogenesis	126	2.316839e-187	2.992661e-183	2.375128e-185	1.539247e+0	ACVRL1,ADAMTS9,APOB,APOE,ARID2,BMP4,BMPR1A,BMPR2,CHD7,COL3A1,DLL4,ENG,EYA1,FOXC1,FOXC2,FOXF1,FOXH1,HAND2,HES1,HEY1,HEY2,HOXA1,HPGD,JAG1,LRP1,MYLK,MYOCD,NF1,NOG,NOTCH1,NOTCH3,NPRL3,NRP1,PDGFRB,PKD2,PRDM1,PROX1,PRRX1,RBPJ,SEC24B,SMAD7,SOX4,SRF,STRA6,TBX1,TBX2,TFAP2B,TGFB2,TGFBR1,VEGFA,WNT11,ZMIZ1	TetrapodAncestor	182.524
GO.Biological.Process	GO:0050778	positive.regulation.of.immune.response	127	7.721707e-187	9.974129e-183	7.853645e-185	1.249764e+0	ABI1,ABL1,ACTR2,ACTR3,ADA,ADAM8,ADORA2B,ANXA1,AP1G1,APOB,ARPC1A,ARPC1B,ARPC2,ARPC4,ARPC5,ATAD5,BAG6,BAX,BCAR1,BCL10,BCL2,BIRC2,BIRC3,BLK,BRAF,BTK,BTRC,C1QA,C1QB,C1QBP,C1QC,C3,C3AR1,C4A,C4B,C4BPA,C4BPB,C5,C6,C7,C8A,C8B,C8G,C9,CADM1,CARD11,CASP8,CCL19,CCL5,CCR2,CCR7,CD14,CD180,CD19,CD1D,CD209,CD226,CD247,CD28,CD300LF,CD36,CD38,CD3D,CD3E,CD3G,CD40,CD46,CD55,CD74,CD79B,CD80,CD86,CDC42,CFH,CFHR1,CFHR5,CFI,CFP,CHUK,CLCF1,CLEC4A,CLEC4C,CLEC4D,CLEC4E,CLEC6A,CLEC7A,CLU,CNPY3,CNR1,COLEC10,COLEC11,COLEC12,CR1,CR2,CRK,CRTAM,CSK,CTLA4,CTSB,CTSL,CUL1,CYFIP1,CYFIP2,DDX58,DENND1B,DHX9,DMBT1,EIF2AK4,ELMO1,ELMO2,ENSG00000173366,EP300,EREG,EXOSC3,EXOSC6,F2RL1,FADD,FAM49B,FBXW11,FCER1G,FCER2,FCN1,FCN2,FCN3,FFAR2,FFAR3,FGG,FGR,FOXP3,FYB1,FYB2,FZD5,GAB2,GATA2,GATA3,GPLD1,GPR32,GPR33,GPRC5B,GRAP2,GRB2,HAVCR2,HCK,HEXIM1,HLX,HMGB1,HMGB2,HMSD,HRAS,HRG,HSP90AB1,HSP90B1,ICAM2,IDO1,IFNB1,IFNG,IFNK,IFNL1,IFNL2,IFNL3,IGLL1,IGLL5,IKBKB,IKBKE,IKBKG,IL12A,IL12B,IL12RB1,IL13,IL15,IL18,IL18RAP,IL1B,IL2,IL21,IL23A,IL23R,IL27RA,IL33,IL4,IL6,IL6ST,INAVA,INPP5D,IRAK1,IRAK3,IRAK4,IRF3,IRF7,IRGM,ITCH,ITGAM,ITGB2,ITK,KARS,KLHL6,KLRK1,KRAS,KRT1,LAT,LAT2,LAX1,LBP,LCK,LCP2,LGALS9,LGMN,LIMK1,LRRC70,LY96,LYN,MALT1,MAP2K6,MAP3K1,MAP3K7,MAPK1,MAPK14,MAPK3,MAPKAPK2,MAPKAPK3,MARCO,MASP1,MASP2,MATR3,MB21D1,MBL2,MEF2C,MIF,MLH1,MMP12,MSH2,MSH6,MUC1,MUC12,MUC13,MUC15,MUC20,MUC3A,MUC4,MUC5AC,MUC5B,MUC6,MUCL1,MYB,MYO10,MYO1C,MYO1G,NCK1,NCKAP1,NCKAP1L,NCR3,NECTIN2,NFAM1,NFATC2,NFKB1,NLRC4,NLRC5,NLRP10,NOD1,NR1H4,NR4A3,NRAS,NSD2,OTULIN,P2RX7,PAG1,PAK1,PAK2,PAK3,PARK7,PARP9,PAXIP1,PDE4B,PDE4D,PDPK1,PGC,PGLYRP1,PGLYRP2,PGLYRP3,PGLYRP4,PHB,PIK3AP1,PIK3C3,PIK3CA,PIK3CD,PIK3R1,PIK3R2,PLA2G1B,PLA2G6,PLCG1,PLCG2,PLD2,PLEKHA1,PLPP4,PLSCR1,POLR3B,POLR3C,POLR3D,POLR3F,PQBP1,PRKACA,PRKACG,PRKCB,PRKCD,PRKCE,PRKCQ,PRKCZ,PRKD2,PRKDC,PSEN1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PSPC1,PTAFR,PTK2,PTPN22,PTPRJ,PYCARD,RAC1,RAF1,RARA,RASGRP1,RBCK1,RBM14,REG3G,RELA,RELB,RFTN1,RFTN2,RGCC,RIF1,RIOK3,RIPK1,RIPK2,RNF31,RPS27A,RPS6KA3,RPS6KA5,RSAD2,S100A1,S100A14,S100A8,S100A9,SASH3,SEMA7A,SERPING1,SFPQ,SH2D1A,SH2D1B,SHB,SIRT1,SKAP2,SLA2,SLAMF6,SLC11A1,SNAI3,SNX4,SOCS5,SPG21,SPON2,SPPL3,SRC,STAT6,STX4,STX7,STXBP1,SUSD4,SYK,TAB1,TAB2,TAB3,TBK1,TEC,TFRC,TGFB1,TGFB2,THEMIS,THEMIS2,THY1,TICAM1,TICAM2,TIRAP,TLR1,TLR10,TLR2,TLR3,TLR4,TLR5,TLR6,TLR9,TMEM173,TMEM189-UBE2V1,TNF,TNFAIP3,TNFRSF13C,TNFRSF14,TNFRSF21,TNFSF13,TNFSF13B,TNIP1,TNIP2,TNIP3,TRAF2,TRAF3,TRAF6,TRAT1,TRIL,TRIM5,TRIM6,TXK,UBC,UBE2D1,UBE2D2,UBE2D3,UBE2N,UNC93B1,UNG,VAMP8,VAV1,VAV2,VAV3,VSIG4,WASF2,WIPF2,WIPF3,WNT5A,XBP1,XCL1,XRCC5,XRCC6,YES1,ZAP70,ZBTB1,ZP3,ZP4	TetrapodAncestor	182.001
GO.Biological.Process	GO:0071222	cellular.response.to.lipopolysaccharide	128	9.119011e-186	1.177903e-181	9.202364e-184	1.478605e+0	ABCA1,ABCC2,ABL1,ADAM9,ADAMTS13,AICDA,AKAP8,ANKRD1,ARG1,AXL,BCR,CACTIN,CARD16,CARD17,CASP1,CCL2,CCL3,CCL5,CCR5,CD14,CD180,CD36,CD40,CD6,CD80,CD86,CDC73,CDK19,CDK4,CEBPB,CEBPE,CMPK2,CPEB1,CSF3,CX3CR1,CXCL10,CXCL16,CXCL6,CXCL8,DAB2IP,EDNRB,GHSR,GSTP1,HAMP,HAVCR2,HCK,HDAC5,HMGB2,HSF1,IFNG,IL10,IL12A,IL12B,IL18,IL1B,IL24,IL6,IRAK1,IRF3,IRF8,IRGM,KLRK1,LBP,LCN2,LILRB2,LITAF,LY96,LYN,MAPK1,MAPK14,MAPK3,MAPK8,MEF2C,MRC1,MTDH,NFKB1,NFKBIB,NLRP7,NOS2,NOS3,NR1D1,NR1H3,NR1H4,NUGGC,OPRK1,PABPN1,PAF1,PDE4B,PDE4D,PLAA,PLSCR4,PPARD,PPARGC1A,PRKCE,PRPF8,PTAFR,PTPN22,PYCARD,RARA,RELA,RIPK2,SCARB1,SHPK,SPON2,SRC,STAP1,STAR,TBXA2R,TFPI,TGFB1,TICAM1,TICAM2,TLR2,TLR4,TLR5,TNF,TNFAIP3,TNFRSF1B,TNIP1,TNIP2,TNIP3,TRAF6,TSPO,UPF1,WNT5A,XBP1,ZC3H12A,ZFP36	TetrapodAncestor	180.929
GO.Biological.Process	GO:0070201	regulation.of.establishment.of.protein.localization	129	1.140937e-183	1.473748e-179	1.142441e-181	1.181675e+0	AACS,ABAT,ABCC8,ABL1,ABLIM3,ACHE,ACSL3,ACSM6,ADAM8,ADAM9,ADCY5,ADIPOQ,ADORA2A,ADRA2A,ADRA2C,AGER,AGTR2,AKT2,ALOX15B,ANGPT1,ANK3,ANKRD1,ANO1,ANXA1,ANXA4,APC2,APOA1,APOA2,APOD,APP,ARF1,ARFIP1,ARG2,ARL2,ARL2BP,ARNTL,ARRB1,ATG13,ATG5,ATP13A2,ATPIF1,AXIN2,B3GAT3,BAD,BAG4,BAMBI,BANK1,BAP1,BARD1,BCAP31,BCAS3,BCL2,BCL2L11,BCL3,BID,BLK,BMP4,BMP6,BMP7,BMP8A,BMPR1A,BNIP3L,BRSK2,C1QTNF12,C1QTNF3,C2CD2L,C2CD5,C5,C8orf4,CABP1,CACNA1A,CACNA1C,CACNA1D,CACNA1E,CACNA2D2,CADM1,CAMK1,CAPN10,CARD16,CARD17,CARD18,CARTPT,CASP1,CASP5,CASP8,CASR,CCDC22,CCL19,CCL2,CCL3,CCL5,CCR7,CCT2,CCT4,CCT5,CCT6A,CCT7,CCT8,CD14,CD2,CD27,CD274,CD34,CD36,CD38,CD40,CD58,CDC42,CDH1,CDK1,CDK16,CDK5,CDK5R1,CDKL2,CDKN1A,CEMIP,CFTR,CHERP,CHIA,CHP1,CHRM1,CHUK,CIB1,CIDEA,CLEC4E,CLEC6A,CLEC9A,CNR1,CNST,CPT1A,CRTAM,CSF1R,CSF3,CSK,CSNK2A2,CTDSPL2,CYB5R1,DAB2,DAB2IP,DACT1,DACT3,DDX58,DERL2,DERL3,DHX9,DISP1,DKC1,DMAP1,DMTN,DNAJA1,DNAJC1,DNAJC27,DNM1L,DOC2B,DPH3,DRD2,DRD3,DRD4,DTWD2,DYNLL1,DYNLL2,DYRK2,E2F1,ECT2,EDA,EDAR,EDEM1,EDEM2,EFNA5,EGF,EGFR,ELMOD1,ENSG00000173366,EPB41L5,EPHA5,ERBB2,ERBB4,ERP29,EXPH5,EZR,F2,F2R,F2RL1,FAF1,FAM20B,FAM3D,FAM89B,FBXW11,FBXW7,FCN1,FERMT1,FFAR1,FFAR2,FFAR4,FGG,FGR,FIS1,FKBP1B,FLNA,FN1,FOXA2,FOXP3,FZD1,FZD5,FZD7,G3BP2,GAPDH,GAPVD1,GAS6,GATA3,GCC2,GCK,GDI1,GHSR,GIP,GIPR,GJA1,GLI3,GLP1R,GLUD1,GLUL,GNAQ,GOLPH3,GOPC,GPAM,GPER1,GPHA2,GPLD1,GPR68,GREM1,GSDMD,GSK3A,GTSE1,HAVCR2,HAX1,HCLS1,HDAC3,HES1,HHAT,HIF1A,HMGB1,HMGCR,HMGN3,HMHB1,HNF4A,HNMT,HPCA,HPS4,HSP90AB1,HSPA8,HSPH1,HTR2B,HTRA2,ICA1,ICE1,IDH2,IFI27,IFNA2,IFNAR1,IFNG,IFNL3,IGF1,IL10,IL12B,IL13,IL17A,IL17F,IL17RA,IL17RB,IL17RC,IL18,IL18R1,IL1A,IL1B,IL1R2,IL1RAP,IL1RL1,IL2,IL23A,IL26,IL33,IL36RN,IL5,IL6,INHBB,INPP5K,INS,IPO5,IRF3,IRS1,IRS2,ISL1,ITGAM,ITGAX,ITPR1,ITPR2,ITPR3,JAGN1,JAK2,JUP,KANK1,KARS,KCNA5,KCNB1,KCNC2,KCNE1,KCNG2,KCNJ11,KCNN3,KCNS3,KEAP1,KIAA0586,KIF20B,KIF5B,KRT20,LACRT,LCP1,LEP,LEPROT,LGALS9,LGR4,LITAF,LLGL2,LPL,LRP1,LRP5,LRRC32,LRRK2,LYN,LYPLA1,MAP4K4,MAPK1,MAPK11,MAPK14,MAPK3,MAPK8,MAPT,MARCKS,MBTPS1,MCU,MDFI,MDM2,MFF,MIEF1,MIEF2,MIF,MIS18A,MMP12,MPC2,MRGPRE,MTNR1B,MTOR,MYBPC1,MYO18A,MYO1C,MYRIP,NDEL1,NDFIP1,NDFIP2,NDUFAF2,NEUROD1,NF1,NKX6-1,NLRP1,NLRP10,NLRP2,NLRP7,NMT1,NMUR1,NNAT,NOL3,NOS2,NOV,NPEPPS,NPFF,NR0B2,NR1D1,NR1H2,NR1H3,NR1H4,NRG1,NRXN1,NSD2,NUCB1,NUP54,NUP58,NUP62,NUTF2,OAZ1,OAZ2,OGG1,OPRM1,OR51E2,ORM1,ORM2,OS9,OXCT1,P2RX7,P3H1,PAEP,PAK1,PAM,PANX1,PARK7,PARL,PARP1,PARP10,PBLD,PCK2,PCM1,PCNT,PDCD10,PDCD5,PDE2A,PDE8B,PEMT,PER2,PFKFB2,PFKL,PHPT1,PIK3C3,PIK3R1,PIK3R2,PIM3,PINK1,PKD1,PKD2,PKDCC,PKIA,PKIG,PLA2G1B,PLA2G6,PLK3,PMAIP1,PML,POLR3A,PPARD,PPP1R13B,PPP3CA,PPP3CB,PPP3CC,PPP3R1,PRDX1,PRELID3A,PRKACA,PRKCA,PRKCD,PRKCE,PRKCZ,PRKN,PRR5L,PSEN1,PSMB7,PSMD10,PSMD8,PSMD9,PTGER4,PTP4A3,PTPN1,PTPN11,PTPN14,PTPN22,PTPN23,PYCARD,PYDC1,PYDC2,RAB11FIP1,RAB11FIP5,RAB23,RAB29,RAB8A,RAC2,RAP1A,RAPGEF3,RASGRP1,RBCK1,RBM22,RBP4,RBPMS,REST,RFX3,RFX6,RGCC,RHBDD3,RHBDF1,RHBDF2,RHOU,RIPK2,RIPOR1,RNF31,RPH3AL,RPL28,RSAD2,RUFY3,RUVBL1,SAA1,SCAMP5,SCFD1,SEC16B,SELENOI,SELENOK,SEMA5A,SERGEF,SERP1,SFN,SFRP1,SFRP2,SFRP5,SH3GLB1,SH3TC2,SIAH3,SIDT2,SIRT1,SIRT3,SIRT4,SLC16A1,SLC25A5,SLC25A6,SLC2A1,SLC2A2,SLC30A8,SLC35D3,SLC51B,SLC8B1,SLC9A3R1,SLC9B2,SMAD4,SMO,SNAI2,SNAP25,SNIP1,SNX12,SOCS1,SORL1,SOX4,SP100,SPHK1,SPIDR,SPPL3,SRC,SRCIN1,SREBF1,SREBF2,SRI,SSC5D,SSTR5,STARD7,STOM,STX1A,STX4,STXBP4,STXBP5,STXBP5L,SUFU,SULF2,SVIP,SYBU,SYK,SYT11,SYT4,SYT7,SYT9,SYTL4,TARDBP,TBC1D10C,TCP1,TDRD12,TENM1,TERF1,TFAP2B,TFDP2,TGFB1,TGFB2,TGFBR1,THRA,TIAM1,TLR1,TLR10,TLR2,TLR3,TLR4,TLR5,TLR6,TLR9,TM7SF3,TM9SF4,TMBIM6,TMEM110,TMEM173,TMEM27,TMEM30B,TNF,TNFRSF14,TNFRSF21,TNFRSF4,TNFRSF9,TNFSF14,TOMM7,TONSL,TP53,TP53BP2,TP63,TP73,TPR,TRAF2,TRAF6,TRIM28,TRIM6,TRIP6,TRPM4,TSG101,TSGA13,TTN,TWIST1,TXN,U2AF1,U2AF2,UBAC2,UBE2D3,UBE2G2,UBE2J1,UBE2J2,UBE2L3,UBL5,UBR5,UCN3,UCP2,UGCG,UHMK1,UNC13B,UQCC2,USP36,UTS2,VAMP2,VEGFC,VPS11,VPS28,VPS35,VSNL1,VTCN1,WBP11,WDR46,WDR75,WLS,WNT3A,WNT5A,WRAP53,WWP2,WWTR1,XBP1,XPO4,XPO5,YOD1,YWHAB,YWHAE,YWHAG,YWHAH,YWHAZ,ZBED3,ZBTB17,ZC3H12A,ZDHHC8,ZIC1,ZPR1	TetrapodAncestor	178.832
GO.Biological.Process	GO:0045766	positive.regulation.of.angiogenesis	130	1.192349e-182	1.540157e-178	1.184736e-180	1.445175e+0	ABL1,ACVRL1,ADM2,AGGF1,ANGPT2,ANGPT4,ANGPTL4,ANXA3,APELA,APLNR,AQP1,BRCA1,BTG1,C3,C3AR1,C5,C6,CCBE1,CCL11,CCR3,CD34,CD40,CHI3L1,CIB1,CTSH,CX3CL1,CX3CR1,CXCL8,CYBB,CYP1B1,CYSLTR2,DDAH1,DLL1,ENG,EPHA1,ERAP1,ETS1,F3,FGF1,FGF2,FLT1,FOXC2,GAB1,GATA2,GATA4,GATA6,GDF2,GHSR,GREM1,HDAC7,HDAC9,HGF,HIF1A,HIPK1,HIPK2,HMGA2,HMGB1,HMOX1,HSPB1,HSPB6,IL1A,IL1B,ISL1,ITGA5,ITGB2,JCAD,LRG1,MTDH,MYDGF,NOS3,NRP1,PDCD6,PDCL3,PIK3R6,PLCG1,PPP1R16B,PRKCA,PRKCB,PRKD1,PRKD2,PTGIS,PTK2B,RAMP2,RAPGEF3,RLN2,RRAS,RUNX1,SASH1,SEMA5A,SFRP2,SIRT1,SIRT6,SPHK1,SRPX2,STIM1,TBXA2R,TEK,TERT,TGFBR2,THBS1,TMIGD2,TNFSF12,TWIST1,UTS2,UTS2R,VASH2,VEGFA,VEGFB,VEGFC,VEGFD,WNT5A,XBP1,ZC3H12A	TetrapodAncestor	177.812
GO.Biological.Process	GO:0016055	Wnt.signaling.pathway	131	1.587097e-182	2.050053e-178	1.564926e-180	1.267029e+0	AES,AGO1,AGO2,AGO3,AGO4,AMER1,AMER2,AMER3,AMOTL1,AMOTL2,AP2A1,AP2A2,AP2B1,AP2M1,AP2S1,APC,APC2,APCDD1,ARHGEF19,ARL6,ARRB2,AXIN2,BCL7B,BCL9,BCL9L,BTRC,CALCOCO1,CALM1,CAMK2A,CAV1,CCAR2,CCDC88C,CCND1,CCNE1,CD24,CDC42,CDC73,CDH3,CDK14,CELSR1,CELSR2,CHD8,CLTC,CPZ,CSNK1A1,CSNK1D,CSNK1E,CSNK1G1,CSNK1G2,CSNK1G3,CSNK2A1,CSNK2A2,CSNK2B,CTNNB1,CTNND1,CTNND2,CUL1,CUL3,CXXC4,DAAM1,DAB2,DACT1,DACT3,DDB1,DDX3X,DISC1,DIXDC1,DKK1,DKK2,DKK3,DKK4,DRAXIN,DRD2,DVL1,DVL3,EGF,FBXW11,FERMT2,FRAT1,FRAT2,FZD1,FZD10,FZD2,FZD3,FZD4,FZD5,FZD6,FZD7,FZD8,FZD9,GATA3,GNAO1,GNG2,GPC4,GPC6,GRHL3,GRK5,GRK6,GSK3A,HBP1,HHEX,HIC1,HMGXB4,KDM6A,KLF4,KLHL12,KREMEN1,KREMEN2,LEF1,LEO1,LGR4,LGR6,LRP4,LRP5,LRP6,LRRFIP2,LRRK2,MACF1,MAGI2,MAP3K7,MARK1,MARK2,MCC,MESD,MOV10,MYC,NDP,NFATC1,NKD2,NKX2-5,NLK,NOTUM,NPHP3,NR4A2,NXN,OTULIN,PAF1,PARD6A,PDE6A,PDE6B,PFN1,PIAS4,PITX2,PLCB1,PLCB3,PLCG2,PLPP3,PPP1CA,PPP3CA,PPP3CB,PPP3R1,PRICKLE1,PRKAA1,PRKAA2,PROP1,PSEN1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTEN,PTK7,PTPRU,PYGO2,RAB5A,RAC1,RARG,RNF138,RNF146,RNF43,ROR2,RPS27A,RSPO1,RSPO2,RSPO3,RSPO4,RTF1,RYK,RYR2,SCYL2,SENP2,SFRP1,SFRP2,SFRP4,SFRP5,SLC9A3R1,SMURF1,SMURF2,SNAI2,SOST,SOSTDC1,SOX17,SOX4,SPIN1,STRN,T,TAX1BP3,TBL1X,TBL1XR1,TCF7L1,TGFB1I1,TIAM1,TLE1,TLE2,TLE3,TLE4,TMEM131L,TMEM64,TNIK,TNKS,TNKS2,TNRC6A,TNRC6B,TNRC6C,TRABD2A,TRABD2B,UBC,VANGL1,VANGL2,VAX2,VPS35,WDR61,WIF1,WISP1,WLS,WNT1,WNT10A,WNT10B,WNT11,WNT16,WNT3,WNT3A,WNT4,WNT5A,WNT6,WNT7A,WNT7B,WNT8A,WNT8B,WNT9A,WNT9B,WWOX,XIAP,ZBED3,ZNRF3	TetrapodAncestor	177.688
GO.Biological.Process	GO:0031347	regulation.of.defense.response	132	1.293022e-181	1.670197e-177	1.265300e-179	1.221166e+0	A2M,ABR,ACE2,ACP5,ADA,ADAM8,ADAMTS12,ADAR,ADCYAP1,ADIPOQ,ADORA1,ADORA2A,ADORA2B,AGER,AGT,AGTR1,AHSG,ANKRD17,ANXA1,AP1B1,AP1G1,AP1M1,AP1M2,AP1S2,AP1S3,AP2A1,AP2A2,AP2B1,AP2M1,AP2S1,APOA1,APOB,APOBEC3F,APOBEC3G,APOD,APOE,ARF1,ARG1,ARG2,ARRB2,ASH1L,ATP6V1H,BAP1,BCL10,BCL6,BCR,BIRC2,BIRC3,BPIFB1,BRD4,BST1,BTK,BTRC,C1QA,C1QB,C1QBP,C1QC,C1QTNF12,C1QTNF3,C3,C3AR1,C4A,C4B,C4BPA,C4BPB,C5,C5orf30,C6,C7,C8A,C8B,C8G,C9,CACTIN,CADM1,CALCRL,CARD11,CASP1,CASP4,CASP5,CASP8,CAV1,CCL3,CCL5,CCR2,CCR7,CD14,CD180,CD19,CD1D,CD209,CD226,CD247,CD28,CD300A,CD300LF,CD36,CD46,CD47,CD55,CD59,CD6,CD81,CD86,CD8B,CD96,CDK19,CFH,CFHR1,CFHR2,CFHR4,CFHR5,CFI,CFP,CHID1,CHUK,CLEC12B,CLEC4A,CLEC4C,CLEC4D,CLEC4E,CLEC6A,CLEC7A,CLU,CNPY3,CNR1,CNR2,COLEC12,CPB2,CPN1,CPN2,CR1,CR2,CREB3L3,CRK,CRTAM,CTSB,CTSL,CUL1,CX3CL1,CX3CR1,CYBA,CYP19A1,DAB2IP,DCST1,DDT,DDX58,DDX60,DHX9,DMBT1,DOCK2,DRD2,DROSHA,DTX3L,DUOXA1,DUOXA2,DUSP10,EDNRB,EGFR,EIF2AK2,EIF2AK4,ELMO1,ELMOD2,ENSG00000173366,EP300,ERAP1,EREG,ESR1,ETS1,F12,F2,F2RL1,FABP4,FADD,FAM3A,FANCA,FBXW11,FCER1G,FCN1,FEM1A,FFAR2,FFAR3,FFAR4,FGG,FGR,FLOT1,FNDC4,FOXF1,FOXP3,GATA3,GBA,GGT1,GHSR,GJA1,GPATCH3,GPER1,GPR17,GPRC5B,GPSM3,GSTP1,HAVCR2,HCK,HEXIM1,HGF,HMGB1,HMGB2,HRAS,HSP90AB1,HSP90B1,HTRA1,ICAM2,IDO1,IFIT1,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNAR1,IFNAR2,IFNB1,IFNG,IFNGR1,IFNGR2,IFNK,IFNLR1,IKBKB,IKBKE,IKBKG,IL10,IL12A,IL12B,IL12RB1,IL15,IL17A,IL17B,IL17F,IL17RA,IL17RB,IL17RC,IL18,IL18RAP,IL1B,IL1R1,IL1R2,IL1RL1,IL1RL2,IL2,IL20,IL20RB,IL21,IL22RA2,IL23A,IL23R,IL27,IL33,IL4,IL6,IL6ST,INAVA,INS,IRAK1,IRAK3,IRAK4,IRF1,IRF3,IRF4,IRF7,IRGM,ISL1,ITCH,ITGA2,ITGAM,ITGB2,JAK2,KARS,KLF4,KLKB1,KLRK1,KRAS,KRT1,LBP,LCK,LDLR,LEP,LGALS9,LGMN,LGR4,LILRA4,LPL,LRRC14,LRRC70,LRSAM1,LY96,LYN,MALT1,MAP2K6,MAP3K1,MAP3K7,MAPK13,MAPK14,MAPK3,MAPKAPK2,MAPKAPK3,MARCO,MAS1,MATR3,MB21D1,MCPH1,MEF2C,MEFV,METRNL,MGLL,MGST2,MMP12,MMP26,MUC1,MUC12,MUC13,MUC15,MUC20,MUC3A,MUC4,MUC5AC,MUC5B,MUC6,MUCL1,MUL1,NCR1,NCR3,NDFIP1,NECTIN2,NFKB1,NLRC3,NLRC4,NLRC5,NLRP1,NLRP10,NLRP6,NLRP7,NLRX1,NMI,NOD1,NOP53,NOS2,NOV,NPY5R,NR1D1,NR1D2,NR1H2,NR1H3,NR1H4,NRAS,NT5E,OPTN,OSM,OSMR,OTUD7A,OTULIN,PAK1,PAK2,PAK3,PARK7,PARP14,PARP9,PBK,PCBP2,PDE2A,PDPK1,PELI1,PENK,PER1,PGC,PGLYRP1,PGLYRP2,PGLYRP3,PGLYRP4,PHB,PIAS1,PIK3AP1,PIK3C3,PIK3CG,PIK3R6,PLA2G2A,PLA2G7,PLCG2,PLSCR1,POLR3B,POLR3C,POLR3D,POLR3F,PPARA,PPARD,PPARG,PQBP1,PRKACA,PRKACG,PRKCD,PRKCE,PRKDC,PROC,PROS1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PSPC1,PTGER3,PTGER4,PTGIS,PTPN1,PTPN11,PTPN22,PTPRS,PYCARD,PYDC2,RAB7B,RAC1,RAF1,RAG1,RASGRP1,RBM14,REG3G,RELA,RELB,RFTN1,RHBDD3,RICTOR,RIOK3,RIPK1,RIPK2,RNASEL,RNF125,RNF135,RNF216,RNF26,RPS27A,RPS6KA3,RPS6KA5,RSAD2,S100A1,S100A12,S100A14,S100A8,S100A9,SAA1,SAMHD1,SARM1,SCGB1A1,SCRIB,SEC14L1,SELE,SELENOK,SEMA7A,SERPINB4,SERPINB9,SERPING1,SETD6,SFPQ,SH2D1A,SH2D1B,SHARPIN,SHPK,SIRT2,SLAMF6,SLC25A6,SMPDL3B,SNAI3,SNCA,SNX4,SOCS1,SOCS3,SOCS5,SPINK5,SPN,SRC,STAT1,STAT2,SUMO1,SUSD4,SYK,SYT11,TAB1,TAB2,TAB3,TAC1,TARBP2,TBC1D23,TBK1,TEK,TGFB1,TGM2,TICAM1,TICAM2,TIRAP,TKFC,TLR1,TLR10,TLR2,TLR3,TLR4,TLR5,TLR6,TLR9,TMEM173,TMEM189-UBE2V1,TNF,TNFAIP3,TNFAIP6,TNFAIP8L2,TNFRSF11A,TNFRSF1A,TNFRSF1B,TNFSF11,TNFSF18,TNIP1,TNIP2,TNIP3,TRAF3,TRAF3IP1,TRAF6,TRAFD1,TREML4,TRIL,TRIM44,TRIM5,TRIM6,TSPAN32,TSPAN6,TXK,TYRO3,UBC,UBE2D1,UBE2D2,UBE2D3,UBE2N,UBQLN1,UCN,UFD1,UNC13B,UNC93B1,USP18,VAMP8,VAV1,VPS35,VTN,WDFY1,WFDC1,WNT5A,XCL1,XIAP,XRCC5,XRCC6,ZC3H12A,ZP3,ZYX	TetrapodAncestor	176.777
GO.Biological.Process	GO:0019216	regulation.of.lipid.metabolic.process	133	7.239116e-180	9.350766e-176	7.030651e-178	1.278838e+0	AADAC,ABCA1,ABCB4,ABCD2,ABCG1,ABHD5,ABHD6,ACACA,ACACB,ACADL,ACADM,ACADVL,ACER1,ACSL1,ACSL3,ADGRF5,ADIPOQ,ADIPOR1,ADIPOR2,ADORA1,ADRA2A,ADRB2,AGT,AGTR1,AKT2,ALAS1,AMBRA1,ANGPTL4,ANGPTL8,ANKRD1,ANXA1,APOA1,APOA2,APOA4,APOA5,APOB,APOBEC1,APOC1,APOC3,APOD,APOE,ARF1,ARV1,ATG14,ATP1A1,AVP,AVPR1A,BBS4,BCL11B,BMP2,BMP5,BMP6,BRCA1,BSCL2,C1QTNF2,C3,CARM1,CAV1,CCDC3,CCKBR,CCL19,CCL21,CCR7,CD36,CD81,CDC42,CDK4,CHRM5,CIDEA,CNEP1R1,CNR1,CPT1A,CPT2,CREB1,CREBL2,CRTC3,CTGF,CYP1A1,CYP27B1,CYP4A11,CYP7A1,CYR61,DAB2IP,DGAT2,DGKQ,DHCR7,DISP3,DKK3,DKKL1,DLAT,DLD,DNAJC15,DRD3,EDF1,EGR1,EIF6,ELOVL6,ENSG00000278139,EPHA8,EPHX2,ERFE,ERLIN1,ERLIN2,ETFBKMT,F2,FABP1,FABP3,FADS1,FASN,FBXW7,FDFT1,FDPS,FGF1,FGF19,FGF2,FGF21,FGFR3,FGFR4,FGR,FHL2,FITM2,FLT1,FMC1,G0S2,GAL,GHSR,GLIPR1,GOLM1,GPAM,GPER1,GPLD1,H2AFY,HDAC3,HMGCR,HMGCS1,HMGCS2,HNF4A,HSD17B13,HTR2A,HTR2B,HTR2C,HTT,ID2,IFNG,IGFBP7,IL1B,INS,INSIG2,IRS1,IRS2,IRS4,ISX,KLF4,KPNB1,LACTB,LDLR,LDLRAP1,LEP,LGALS12,LMF1,LONP2,LSR,LSS,LYN,MALRD1,MBTPS1,MBTPS2,ME1,MID1IP1,MLXIPL,MLYCD,MTOR,MVD,NCOA1,NCOA6,NCOR2,NFKB1,NFYA,NFYB,NFYC,NPAS2,NPC2,NR1D1,NR1D2,NR1H2,NR1H3,NR1H4,NR4A3,NRBF2,NSMAF,OPA3,ORMDL1,ORMDL2,ORMDL3,PANK2,PDGFA,PDGFB,PDGFRB,PDHA1,PDHA2,PDHB,PDHX,PDK2,PDK3,PDP2,PDPR,PEX11A,PIK3CG,PIK3IP1,PIK3R1,PIK3R2,PIK3R3,PIK3R5,PIK3R6,PLA2G6,PLIN2,PLIN5,PLPP1,PMVK,PNPLA2,POR,PPARA,PPARG,PPARGC1A,PPP2R5A,PPP4R3B,PRKAA1,PRKAA2,PRKAG2,PRKCD,PRKCE,PRKD1,PROX1,PSAP,PSAPL1,PTK2,PTK2B,RARRES2,RB1,RBL1,REST,RGL1,RGN,RORC,RUBCN,RXRA,SC5D,SCARB1,SCD,SEC14L2,SERPINA12,SERPINA3,SESN2,SIK1,SIN3B,SIRT1,SIRT4,SLC27A1,SLC45A3,SMPD2,SMPD3,SNAI1,SNAI2,SNCA,SOD1,SORBS1,SP1,SPTLC1,SPTLC2,SQLE,SRC,SREBF1,SREBF2,STAR,STARD4,STUB1,SULT2A1,TAZ,TBL1X,TBL1XR1,TEK,TGFB1,TGS1,THRA,THRSP,TIAM2,TM7SF2,TNF,TNFAIP8L3,TNFRSF1A,TNFRSF21,TRIB3,TSPO,TWIST1,TXNRD1,TYSND1,UGT1A1,UGT1A8,UGT1A9,VAC14,VAV2,VAV3,VDR,WDR81,WDR91,WDTC1,WNT4,ZP3	TetrapodAncestor	175.029
GO.Biological.Process	GO:0051251	positive.regulation.of.lymphocyte.activation	134	3.260638e-179	4.211766e-175	3.143109e-177	1.319451e+0	ADA,ADAM8,AGER,AIF1,ANXA1,AP1G1,AP3D1,ATAD5,ATP11C,AXL,BAD,BCL10,BCL2,BCL6,BST1,BTK,BTLA,CARD11,CAV1,CCDC88B,CCL19,CCL2,CCL21,CCL5,CCR2,CCR7,CD1D,CD209,CD24,CD247,CD27,CD274,CD276,CD28,CD320,CD38,CD3D,CD3E,CD3G,CD40,CD46,CD47,CD5,CD55,CD59,CD6,CD74,CD80,CD81,CD83,CD86,CDC42,CDKN1A,CHRNB2,CLCF1,CLECL1,CORO1A,CSK,CTLA4,DHPS,DNAJA3,DOCK8,DUSP10,EBI3,EFNB1,EFNB2,EFNB3,EPO,EXOSC3,EXOSC6,FADD,FAM49B,FGF10,FLOT2,FLT3LG,FOXP3,GAS6,GATA3,GLI2,GLI3,GPAM,GPR183,GRAP2,GRB2,HAVCR2,HES1,HHLA2,HLX,HMGB1,HSPH1,ICOS,IFNG,IGF1,IGF2,IGFBP2,IGLL1,IGLL5,IHH,IL12A,IL12B,IL12RB1,IL13,IL15,IL18,IL1B,IL1RL2,IL2,IL21,IL23A,IL23R,IL36B,IL4,IL5,IL6,IL6ST,IL7,IL7R,INPP5D,IRS2,ITPKB,JAK3,KIRREL1,KLRK1,LCK,LEP,LGALS1,LGALS9,LILRB2,LILRB4,LYN,MALT1,MAP3K14,MAP3K7,MAP3K8,MEF2C,MIF,MLH1,MMP14,MSH2,MSH6,MYB,NCK1,NCK2,NCKAP1L,NFATC2,NPHS1,NSD2,PAK1,PAK2,PAK3,PAXIP1,PCID2,PDCD1,PDCD1LG2,PDPK1,PELI1,PIK3CA,PIK3R1,PIK3R6,PNP,PPP2R3C,PRDM1,PRKCQ,PRKCZ,PTPN11,PYCARD,RAC1,RAG1,RARA,RASAL3,RASGRP1,RIF1,RIPK2,RPS3,SART1,SASH3,SELENOK,SHB,SIRPG,SLC39A10,SOCS1,SOCS5,SPN,SRC,STAT6,SYK,TAC1,TESPA1,TFRC,TGFB1,TGFBR2,THY1,TICAM1,TIRAP,TLR4,TLR9,TMIGD2,TNFRSF13C,TNFRSF14,TNFRSF4,TNFSF11,TNFSF13,TNFSF13B,TNFSF14,TNFSF9,TNIP2,TRAF2,TRAF6,UNG,VAV1,VAV3,VCAM1,VNN1,VTCN1,WNT3A,XBP1,XCL1,YES1,ZAP70,ZBTB1,ZBTB16,ZMIZ1,ZNF335,ZP3,ZP4	TetrapodAncestor	174.376
GO.Biological.Process	GO:0071216	cellular.response.to.biotic.stimulus	135	6.797064e-179	8.779768e-175	6.503532e-177	1.435747e+0	ABCA1,ABCB4,ABCC2,ABL1,ADAM9,ADAMTS13,AICDA,AKAP8,ANKRD1,APAF1,ARG1,ATG10,AXL,BCR,BTK,CACTIN,CARD16,CARD17,CASP1,CCDC47,CCL2,CCL3,CCL5,CCR5,CD14,CD180,CD36,CD40,CD6,CD80,CD86,CDC73,CDK19,CDK4,CEBPB,CEBPE,CMPK2,CPEB1,CSF3,CX3CR1,CXCL10,CXCL16,CXCL6,CXCL8,DAB2IP,EDNRB,EIF2AK3,EME1,FBXO18,FZD5,GHSR,GSTP1,HAMP,HAVCR2,HCK,HDAC5,HMGB2,HSF1,HSPA5,IFNG,IGFBPL1,IL10,IL12A,IL12B,IL18,IL1B,IL24,IL6,IRAK1,IRF3,IRF8,IRGM,KLRK1,LBP,LCN2,LILRB2,LITAF,LY96,LYN,MAPK1,MAPK14,MAPK3,MAPK8,MEF2C,MRC1,MTDH,MUS81,NFKB1,NFKBIB,NLRP7,NOS2,NOS3,NR1D1,NR1H3,NR1H4,NUGGC,OPRK1,PABPN1,PAF1,PDE4B,PDE4D,PLAA,PLSCR4,PPARD,PPARGC1A,PPP1R15B,PRKCE,PRPF8,PTAFR,PTPN22,PYCARD,RARA,RELA,RIPK2,SCARB1,SHPK,SIRT2,SLX4,SMC1A,SPON2,SRC,STAP1,STAR,SYK,TBXA2R,TFPI,TGFB1,TICAM1,TICAM2,TIRAP,TLR1,TLR2,TLR4,TLR5,TLR6,TMCO1,TNF,TNFAIP3,TNFRSF1B,TNIP1,TNIP2,TNIP3,TP53,TRAF6,TREM2,TSPO,TXNIP,UPF1,WFS1,WNT5A,XBP1,ZC3H12A,ZFP36	TetrapodAncestor	174.057
GO.Biological.Process	GO:0048762	mesenchymal.cell.differentiation	136	8.496572e-179	1.097502e-174	8.069869e-177	1.336052e+0	ADAM15,ALX1,AMELX,AMER1,BCL2,BMP2,BMP4,BMP7,BMPR1A,CFL1,CTNNB1,CUL7,CYP26C1,DDX17,DDX5,DLG5,EDN1,EDN3,EDNRB,EFNA1,EFNB1,ENG,EOMES,EPB41L5,ERBB4,ERG,FAM83D,FGF10,FGF19,FGFR1,FGFR2,FOXC1,FOXC2,FOXF2,GBX2,GDNF,GSC,HAND2,HAS2,HES1,HEY1,HEY2,HEYL,HGF,HIF1A,HMGA2,HNRNPAB,HTR2B,ISL1,JAG1,KBTBD8,KITLG,KLHL12,LAMA5,LEF1,LOXL2,LOXL3,LRP6,MAPK1,MAPK3,MEF2C,MSX1,MSX2,NOG,NOLC1,NOTCH1,NRG1,NRP1,NRTN,OLFM1,OSR1,OVOL2,PAX2,PDCD6,PEF1,PHACTR4,PHOX2B,PITX2,RANBP3L,RBPJ,RDH10,RET,RFLNB,RTN4,S100A4,SEMA3A,SEMA3C,SFRP1,SIX2,SMAD4,SMO,SNAI1,SNAI2,SOX10,SOX11,SOX8,SOX9,SPRY1,STAT1,TAPT1,TBX1,TCF21,TCOF1,TGFB1,TGFB2,TGFBR1,TMEM100,TRIM28,TWIST1,WNT10A,WNT11,WNT16,WNT4,WNT5A,WNT8A,WWTR1	TetrapodAncestor	173.96
GO.Biological.Process	GO:0002697	regulation.of.immune.effector.process	137	7.021654e-178	9.069870e-174	6.620343e-176	1.326499e+0	A2M,ABR,ADGRE2,ADORA2B,AGER,ANGPT1,ANKRD17,ANXA1,AP1B1,AP1G1,AP1M1,AP1M2,AP1S2,AP1S3,AP2A1,AP2A2,AP2B1,AP2M1,AP2S1,APLF,APOA1,APOA2,APOBEC3F,APOBEC3G,ARF1,ARG1,ARRB2,ATAD5,ATG5,ATP6V1H,BCL10,BCL6,BCR,BIRC2,BIRC3,BST2,BTK,C12orf4,C1QA,C1QB,C1QBP,C1QC,C3,C3AR1,C4A,C4B,C4BPA,C4BPB,C5,C6,C7,C8A,C8B,C8G,C9,CADM1,CCL19,CCL2,CCR2,CD19,CD226,CD247,CD28,CD300A,CD36,CD40,CD46,CD55,CD59,CD74,CD80,CD81,CD86,CD8B,CD96,CFH,CFHR1,CFHR2,CFHR4,CFHR5,CFI,CFP,CLC,CLCF1,CLEC12B,CLEC4G,CLU,CPB2,CPN1,CPN2,CR1,CR2,CRK,CRTAM,DDX58,DDX60,DHX9,DOCK2,DTX3L,DUSP10,DUSP22,EIF2AK2,EIF2AK4,ELMO1,ELMOD2,EXOSC3,EXOSC6,F2,F2RL1,FADD,FAM49B,FCER1G,FCER2,FER,FES,FFAR2,FFAR3,FGR,FOXF1,FOXJ1,FOXP3,FZD5,GAB2,GATA2,GATA3,GPATCH3,GPRC5B,HAVCR2,HCK,HLX,HMGB1,HMOX1,HTRA1,IFIT1,IFNA2,IFNB1,IFNG,IFNL1,IFNLR1,IL10,IL12A,IL12B,IL12RB1,IL13,IL13RA2,IL15,IL18,IL18RAP,IL1B,IL2,IL20RB,IL21,IL23A,IL23R,IL27,IL27RA,IL33,IL4,IL5,IL6,IL7R,INS,IRAK3,IRF4,ITCH,ITGAM,ITGB2,JAK3,KARS,KLRK1,LBP,LCK,LEP,LGALS3,LGALS9,LOXL3,LYN,MALT1,MAP3K7,MAPK14,MAPK3,MB21D1,MIF,MLH1,MMP12,MSH2,MSH6,MUL1,MYB,MYO18A,MZB1,NCR1,NCR3,NDFIP1,NECTIN2,NLRX1,NOP53,NR4A3,NSD2,P2RX7,PAK2,PARP9,PAXIP1,PCBP2,PDPK1,PGC,PGLYRP1,PGLYRP2,PGLYRP3,PHB,PIK3R6,PKN1,PPP3CB,PQBP1,PRAM1,PRKCZ,PRKDC,PROS1,PTAFR,RAC1,RAC2,RAP1A,RAPGEF1,RARA,RASGRP1,RBP4,RC3H1,RIF1,RIOK3,RIPK2,RIPK3,RNF125,RNF216,RNF26,RSAD2,SASH3,SCRIB,SEC14L1,SELENOK,SEMA7A,SERPINB4,SERPINB9,SERPING1,SH2D1A,SH2D1B,SHB,SLAMF6,SMAD7,SNX4,SOCS5,SPINK5,SPN,SPON2,STAT1,STAT6,STX4,STX7,STXBP1,STXBP2,STYK1,SUSD4,SYK,TARBP2,TFRC,TGFB1,TGFB2,THOC1,TKFC,TLR3,TLR4,TLR9,TMBIM6,TMEM173,TNF,TNFAIP3,TNFRSF14,TNFRSF4,TNFSF13,TNFSF18,TRAF2,TRAF3,TRAF3IP1,TRAF6,TRIL,TRIM44,TRIM6,TRPM4,TSPAN32,TSPAN6,UFD1,UNG,VAMP8,VAV1,VTN,WNT5A,XBP1,XCL1,ZBTB1,ZC3H12A,ZNF683,ZP3	TetrapodAncestor	173.042
GO.Biological.Process	GO:1904018	positive.regulation.of.vasculature.development	138	1.472632e-177	1.902199e-173	1.378405e-175	1.404811e+0	ABL1,ACVRL1,ADM2,AGGF1,ANGPT2,ANGPT4,ANGPTL4,ANXA3,APELA,APLNR,AQP1,BRCA1,BTG1,C3,C3AR1,C5,C6,CCBE1,CCL11,CCR3,CD34,CD40,CFLAR,CHI3L1,CIB1,CTH,CTSH,CX3CL1,CX3CR1,CXCL8,CYBB,CYP1B1,CYSLTR2,DDAH1,DLL1,EFNB2,EGR1,ENG,EPHA1,ERAP1,ETS1,F3,FGF1,FGF2,FLT1,FOXC2,GAB1,GATA2,GATA4,GATA6,GDF2,GHSR,GPER1,GREM1,HDAC7,HDAC9,HGF,HIF1A,HIF1AN,HIPK1,HIPK2,HMGA2,HMGB1,HMOX1,HSPB1,HSPB6,IL1A,IL1B,ISL1,ITGA5,ITGB2,JCAD,LRG1,MTDH,MYDGF,MYOCD,NOS3,NOTCH1,NRP1,PDCD6,PDCL3,PDGFB,PDGFD,PIK3R6,PLCG1,PPP1R16B,PRKCA,PRKCB,PRKD1,PRKD2,PTGIS,PTK2B,RAMP2,RAP1A,RAPGEF2,RAPGEF3,RLN2,RRAS,RUNX1,SASH1,SEMA5A,SERPINB7,SFRP2,SIRT1,SIRT6,SPHK1,SRPX2,STIM1,TBXA2R,TEK,TERT,TGFBR2,THBS1,TMEM100,TMIGD2,TNFSF12,TWIST1,UTS2,UTS2R,VASH2,VEGFA,VEGFB,VEGFC,VEGFD,WNT5A,XBP1,ZC3H12A	TetrapodAncestor	172.721
GO.Biological.Process	GO:0045862	positive.regulation.of.proteolysis	139	2.667805e-177	3.446004e-173	2.479139e-175	1.289559e+0	ACER2,ADAM8,ADAM9,ADRA2A,ADRM1,AIFM1,AKIRIN2,ANAPC1,ANAPC11,ANAPC16,ANAPC2,ANAPC4,ANAPC5,ANGPTL8,ANKIB1,ANTXR1,APAF1,APOE,APP,ARIH1,ARL6IP5,ARRB1,ASPH,ASTL,ATPIF1,AURKA,AURKAIP1,BAD,BAK1,BAX,BBS7,BCAP31,BCL10,BCL2L10,BCL2L11,BCL2L13,BID,BLID,BTRC,C3,C6,CASP1,CASP2,CASP3,CASP8,CASP9,CAV1,CAV3,CCBE1,CCDC22,CCK,CCNB1,CDC16,CDC20,CDC23,CDC26,CDC27,CDK1,CEBPA,CHFR,CIDEB,CLEC3B,CLN6,CLPX,CLU,CNTN2,COL4A3,CR1,CRADD,CSNK1A1,CSNK1D,CSNK1E,CTGF,CTSC,CTSH,CUL1,CYCS,CYFIP2,CYR61,DAB2,DAB2IP,DAP,DAPK1,DDRGK1,DDX3X,DET1,DISC1,DLC1,DVL1,ECSCR,EFNA1,EFNA3,EGF,EGLN3,EIF2AK3,EPHA4,F12,F2R,F3,FADD,FAM162A,FAS,FASLG,FBLN1,FBXO22,FBXO5,FBXW11,FBXW7,FGFR4,FIS1,FMR1,FN1,FURIN,FZR1,GBA,GPER1,GPLD1,GRAMD4,GSN,HDAC2,HERPUD1,HIP1,HIP1R,HMGB1,HPN,HSF1,HSPBP1,HTRA2,IFI27,IFNG,IFT57,IL1B,IL33,IST1,JAK2,KARS,KCNE2,KEAP1,KLKB1,LCK,LGALS9,LONRF1,LONRF2,LONRF3,LRRK2,LYN,MAD2L1,MAP3K5,MAPK14,MAPK3,MAPT,MDM2,MEFV,MELTF,MMP14,MTCH1,MUL1,MYC,MYH9,NEK5,NGF,NGFR,NKD2,NKX3-1,NLRC4,NLRP1,NLRP2,NOD1,NOP53,NRDC,NUB1,OGT,PACSIN3,PDCD2,PDCD5,PDCD6,PERP,PHB,PIAS1,PICALM,PIDD1,PINK1,PLGRKT,PLK1,PLK2,PLK3,PMAIP1,PML,PPARG,PPM1F,PRELID1,PRICKLE1,PRKN,PSEN1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTEN,PTK2,PTK2B,PYCARD,RAD23A,RCHY1,REST,RFWD2,RGN,RHBDD1,RIPK1,RIPK2,RNF114,RNF125,RNF138,RNF139,RNF14,RNF144A,RNF144B,RNF166,RNF180,RNF19B,RNF217,RNF40,ROBO1,RPS27A,RPS27L,RPS3,S100A8,S100A9,SEMG1,SEMG2,SERPINB3,SFRP2,SGTA,SIRT1,SIRT2,SMAD7,SMURF1,SNCA,SNX9,SOCS4,SOCS5,SOX7,SRC,ST18,STUB1,SUMO1,SUMO2,TAF1,TBC1D10A,TMTC3,TNF,TNFRSF10A,TNFRSF10B,TNFRSF1B,TNFSF10,TNFSF15,TNIP1,TNP1,TNP2,TRADD,TRAF2,TRIB1,TRIB2,TRIB3,TRIM32,UBC,UBE2C,UBE2D1,UBE2E1,UBE2V2,UBQLN1,VCP,WDR35,WNT3A,XBP1,XDH,ZC3H12A,ZFAND2A	TetrapodAncestor	172.463
GO.Biological.Process	GO:0006897	endocytosis	140	1.639848e-176	2.118192e-172	1.512994e-174	1.233024e+0	AAK1,ABCA1,ABI1,ABL1,ACHE,ACKR2,ACKR3,ACKR4,ACTR2,ACTR3,ADGRB1,ADORA1,ADORA2A,ADRB2,AGER,AHSG,AIF1,ALB,ALOX15,AMBP,AMN,AMPH,ANK2,ANXA1,ANXA3,AP2A1,AP2A2,AP2B1,AP2M1,AP2S1,APLP1,APOA1,APOB,APOBR,APOE,APOL1,APP,ARC,ARHGAP12,ARHGAP25,ARHGAP27,ARPC1A,ARPC1B,ARPC2,ARPC4,ARPC5,ARRB1,ARRB2,ASGR1,ATP6V1H,AXL,BCL2L1,BECN1,BIN1,C3,C4B,C9orf72,CACNG2,CALCR,CALCRL,CALR,CALY,CANX,CAP1,CARMIL1,CAV1,CAV2,CAV3,CD14,CD163,CD163L1,CD209,CD247,CD36,CD3G,CD47,CD5,CD5L,CD6,CD81,CD9,CD93,CDC42,CDC42SE1,CDK5,CEBPE,CFI,CLEC4M,CLEC7A,CLEC9A,CLINT1,CLN3,CLTA,CLTB,CLTC,CLTCL1,CNTN2,COLEC11,COLEC12,CORO1A,CRK,CSNK1A1,CSNK1D,CSNK1E,CSNK1G1,CSNK1G2,CSNK1G3,CTTN,CUBN,CXCL16,CXCL8,CXCR1,CXCR2,CYFIP1,CYFIP2,CYTH2,DAB2,DBNL,DENND1A,DGKD,DLL1,DMBT1,DNAJC13,DNER,DNM1,DNM1L,DNM2,DOCK2,DPYSL2,DRD2,DRD3,EEA1,EHBP1,EHD1,EHD2,EHD4,ELMO1,ELMO2,ELMO3,ENDOU,ENPP1,ENPP2,ENPP3,EPN1,EPN2,EPS15,EPS15L1,EQTN,ESYT2,EZR,FCER1G,FCHO1,FCHO2,FCN1,FCN2,FCN3,FGR,FKBP15,FNBP1,FNBP1L,GAK,GAPVD1,GAS6,GATA2,GHR,GPR107,GRB2,GRIA1,GRK2,GRK3,GRK4,GSN,GTF2H2,GULP1,HBA1,HBA2,HBB,HCK,HHIPL1,HIP1,HIP1R,HMGB1,HOOK2,HP,HPR,HRAS,HSP90AB1,HSP90B1,HSPG2,HSPH1,HTR1B,HTR2B,HYOU1,IGF2R,IGLL1,IGLL5,IRF8,ITGA4,ITGAM,ITGAV,ITGB1,ITGB2,ITSN1,ITSN2,JCHAIN,JMJD6,LBP,LDLR,LDLRAD3,LDLRAP1,LEP,LEPR,LGALS3BP,LIMK1,LMBR1L,LMBRD1,LOXL2,LOXL3,LOXL4,LRP1,LRP10,LRP1B,LRP3,LRP4,LRP5,LRP6,LRP8,LRRK2,LRSAM1,LYN,M6PR,MAPK1,MAPK3,MAPKAPK2,MAPKAPK3,MARCH2,MARCH3,MARCO,MASP1,MBL2,MEGF10,MERTK,MESD,MFGE8,MIB1,MICALL1,MLC1,MRC1,MRC2,MSR1,MYH9,MYO10,MYO1C,MYO1E,MYO1G,MYO6,NCF2,NCF4,NCK1,NCKAP1,NCKAP1L,NECAP1,NECAP2,NEURL1B,NLGN1,NLGN3,NLGN4X,NLGN4Y,NME1,NPC1,NR1H3,OLR1,OPHN1,P2RX7,PACSIN2,PACSIN3,PAK1,PDIA6,PDLIM7,PEAR1,PECAM1,PI4KB,PICALM,PIK3C2A,PIK3C3,PIK3CA,PIK3CG,PIK3R1,PIK3R2,PIP5K1A,PIP5K1C,PLA2G6,PLCG1,PLCG2,PLD2,PLPP4,PPT1,PRG4,PRKCD,PRKCE,PRSS12,PSTPIP1,PTK2,PTX3,PYCARD,RAB1A,RAB22A,RAB31,RAB34,RAB39A,RAB5A,RAB7A,RABEP1,RABEP2,RABEPK,RABGAP1L,RABGEF1,RAC1,RALBP1,RAMP1,RAMP2,RARA,RBSN,REPS1,RIN2,RIN3,RINL,RUBCN,RUFY1,SAA1,SBSPON,SCARA3,SCARA5,SCARB1,SCFD1,SCGB3A2,SCRIB,SCYL2,SGIP1,SH3BP1,SH3BP4,SH3GL1,SH3GL2,SH3GL3,SH3KBP1,SIGLEC1,SLC11A1,SLC9B2,SNAP25,SNCA,SNX1,SNX10,SNX17,SNX18,SNX2,SNX30,SNX32,SNX4,SNX5,SNX6,SNX7,SNX8,SNX9,SORL1,SPG11,SPON2,SRC,SRPX,SSC4D,SSC5D,STAB2,STEAP2,STON2,SUSD2,SYK,SYNJ1,SYT1,SYT2,SYT5,SYT7,SYT8,TFR2,TFRC,TGFBR2,TGM2,THBS1,TINAG,TINAGL1,TM9SF4,TMEM108,TMEM175,TMPRSS13,TMPRSS15,TMPRSS2,TMPRSS3,TMPRSS4,TMPRSS5,TNK2,TOM1,TREM2,TRIP10,TSC2,TUB,TULP1,TXNDC5,TYRO3,UBE3A,UNC119,USP20,VAV1,VAV2,VAV3,VLDLR,VTN,WASF2,WIPF2,WIPF3,XKR8,YES1	TetrapodAncestor	171.674
GO.Biological.Process	GO:0016477	cell.migration	141	1.971725e-171	2.546877e-167	1.806296e-169	1.154199e+0	AAMP,ABI2,ABL1,ACVRL1,ADAM8,ADAM9,ADAMTS12,ADGRA2,ADGRE2,ADGRG1,ADGRL3,AGTR1,AJUBA,ALKBH1,ALX1,AMOT,AMOTL1,ANGPT1,ANGPT2,ANGPT4,ANLN,ANO6,ANXA1,APBB2,APC,APCDD1,APELA,APOA1,APOB,ARC,ARF4,ARHGAP35,ARHGEF16,ARID5B,ARL13B,ARPC5,ARRB2,ARTN,ARX,ASAP3,ASCL1,ASPM,ASTN1,ATOH1,ATP1B1,ATP1B2,ATP1B3,AUTS2,AVL9,AXL,B4GALT1,BAMBI,BARHL1,BAX,BBS4,BCAR1,BCL11B,BDKRB1,BIN3,BLK,BRAT1,BSG,BTG1,C16orf45,C3AR1,C5,CAP1,CARMIL1,CARMIL2,CAV1,CCDC88A,CCK,CCKAR,CCL1,CCL11,CCL13,CCL14,CCL15,CCL15-CCL14,CCL16,CCL17,CCL18,CCL19,CCL2,CCL21,CCL22,CCL23,CCL27,CCL28,CCL3,CCL3L3,CCL4,CCL4L2,CCL5,CCL7,CCL8,CCR1,CCR2,CCR4,CCR5,CCR6,CCR7,CD151,CD2,CD24,CD2AP,CD34,CD44,CD47,CD58,CD63,CD74,CDC42,CDC42BPA,CDC42BPB,CDH13,CDH2,CDK1,CDK5,CDK5R1,CDK5R2,CDKL5,CELSR1,CEND1,CER1,CFL1,CH25H,CHGA,CHL1,CKLF,CNR2,CNTN2,COL1A1,COL1A2,COL5A1,CORO1A,CORO1B,CRB2,CSF3R,CSPG4,CTGF,CTNNA2,CTNNB1,CTTN,CUL3,CUZD1,CX3CL1,CX3CR1,CXADR,CXCL1,CXCL10,CXCL11,CXCL13,CXCL14,CXCL16,CXCL2,CXCL3,CXCL5,CXCL6,CXCL8,CXCL9,CXCR1,CXCR2,CXCR3,CXCR4,CXCR5,CYP1B1,CYR61,DAB1,DAB2IP,DAPK2,DBH,DCC,DCDC2,DCHS1,DCX,DDIT4,DDR1,DEPDC1B,DGKZ,DISC1,DIXDC1,DMRT1,DNER,DOCK4,DOCK8,DOK2,DRD1,DRD2,EDN2,EDN3,EDNRB,EFHC1,EFNA1,EFNB1,EFNB2,EGFR,EGR3,ELMO1,ELMO2,ELMO3,ELP3,EMILIN1,EMP2,EMX2,ENG,ENPEP,EPB41L5,EPCAM,EPHA2,EPHA3,EPHA4,EPHA8,EPHB1,EPHB3,EPHB4,EPS8,EPX,ERBB4,ERG,ESAM,F11R,F2,F2RL1,FAM83D,FAT1,FAT2,FBXO45,FCAMR,FCER1G,FER,FERMT1,FES,FEZF1,FFAR2,FGF10,FGF13,FGF19,FGF2,FGFR1,FGFR4,FGR,FLNA,FLRT3,FLT1,FMNL1,FMNL3,FN1,FOXC1,FOXE1,FOXG1,FOXJ1,FOXN1,FRK,FSCN1,FSCN3,FUT10,FUT7,FUT8,FZD3,GAB1,GAS6,GATA2,GATA3,GBF1,GBX2,GDNF,GFRA3,GIPC1,GLG1,GLI3,GOLPH3,GP6,GPC1,GPC6,GPLD1,GPM6A,GPR15,GPR183,GPR32,GPR33,GRAP,GRAP2,GRB2,GRB7,GREM1,GSK3A,GYPC,HAND2,HBEGF,HCK,HES1,HGF,HIF1A,HMGB1,HMGB2,HRAS,HSD3B7,HTR2B,HTR6,ID1,IFNG,IGLL1,IL10,IL12A,IL12B,IL16,IL17RA,IL17RC,IL1B,IL6,IL6R,INPP5D,IRAK4,ISL1,ITGA1,ITGA11,ITGA2,ITGA3,ITGA4,ITGA5,ITGA9,ITGAM,ITGAV,ITGAX,ITGB1,ITGB2,ITGB7,JAGN1,JAK2,JAK3,JAM2,JAM3,JAML,JCHAIN,JUP,KALRN,KCTD13,KIAA0319,KIRREL3,KITLG,KRAS,KRT16,KRT2,L1CAM,LAMA5,LAMB1,LBP,LCK,LCP1,LEF1,LEP,LGALS3,LGALS8,LHX1,LHX6,LIMD1,LOXL2,LPAR1,LRP5,LRRK2,LTB4R2,LURAP1,LYN,MADCAM1,MAG,MARK1,MARK2,MATN2,MBOAT7,MCOLN2,MDGA1,MDK,MEF2C,MEGF10,MEGF8,MERTK,MESP1,MIF,MIXL1,MMP1,MMP12,MMP14,MMP9,MSN,MSX2,MYH9,MYO18A,MYO1G,NANOS1,NCK1,NCK2,NCKAP1L,NDEL1,NDNF,NDRG4,NET1,NEUROD4,NFATC2,NHSL1,NKX2-3,NKX6-1,NOS3,NOTCH1,NOV,NR4A1,NR4A2,NRAS,NRDC,NRG1,NRG3,NRP1,NRTN,NTRK2,NTRK3,NUP188,NUP85,OGDH,OLIG3,OLR1,OPHN1,OVOL2,P2RY1,PAFAH1B1,PAK2,PAK3,PAK4,PAK5,PALLD,PARP9,PAXIP1,PCM1,PDCD10,PDE4B,PDE4D,PDGFB,PDGFRB,PDILT,PDPK1,PDPN,PEAK1,PECAM1,PEX13,PEX7,PF4,PF4V1,PHACTR4,PHOX2B,PIK3C2A,PIK3C2B,PIK3C2G,PIK3CA,PIK3CD,PIK3CG,PIK3R1,PIK3R2,PIP5K1A,PIP5K1C,PITX2,PKN1,PLA2G1B,PLAT,PLAU,PLCG1,PLEKHG5,PLEKHO1,PLET1,PLG,PLPP1,PLPP3,PLXNA2,PLXNB1,PLXND1,PML,PODXL,PODXL2,POMGNT2,POU3F2,POU3F3,POU4F1,PPARD,PPBP,PPIL2,PPP1R9B,PREX1,PRKCD,PRKCI,PRKCQ,PRKCZ,PRKG1,PRKX,PROC,PROCR,PROP1,PROS1,PROX1,PRPF40A,PRSS3,PSEN1,PSTPIP2,PTEN,PTK2,PTK2B,PTK7,PTP4A3,PTPN11,PTPRK,PTPRO,PXN,RAB13,RAB1A,RAC1,RAPGEF2,RASGEF1A,RBFOX2,RELN,RERE,RET,RHBDF1,RHOC,RHOG,RIC8A,ROBO1,ROR2,RTN4,S100A12,S100A2,S100A8,S100A9,S100P,S1PR1,SAA1,SAA2,SAA2-SAA4,SAA4,SATB2,SBDS,SBK2,SCARB1,SCG2,SCRIB,SCYL3,SDC2,SDC4,SDCBP,SELE,SELL,SELP,SEMA3A,SEMA3C,SEMA4C,SEMA5A,SETD2,SGPL1,SH3BP1,SH3KBP1,SHC1,SHROOM2,SIRPA,SIRPG,SIX2,SLA,SLA2,SLC16A1,SLC16A8,SLC3A2,SLC7A10,SLC7A11,SLC7A5,SLC7A6,SLC7A7,SLC7A8,SLC7A9,SLC9A1,SLIT2,SMO,SNAI1,SNAI2,SOCS7,SOS1,SOX1,SOX10,SOX17,SOX18,SOX8,SPATA13,SPEF1,SPN,SPNS2,SPOCK1,SRC,SRF,SRGAP2,SRGAP2C,SSTR4,STARD13,STRIP2,STYK1,SUN1,SUN2,SYK,SYNE2,T,TAOK2,TBX1,TBX20,TBX5,TDGF1,TEK,TGFB1,TGFB2,TGFBR1,THBD,THBS1,THBS4,TIAM1,TLX3,TMEFF2,TMEM201,TNF,TNFAIP1,TNFRSF10A,TNFRSF10B,TNFRSF10D,TNFRSF11A,TNFRSF12A,TNFSF11,TNFSF12,TNK2,TNN,TNR,TNS1,TNS3,TOR1A,TREM1,TRIM46,TRPM2,TRPM4,TSPO,TUBB2B,TWIST1,TYRO3,UMOD,USP9X,USP9Y,VANGL2,VAV1,VAV2,VAV3,VCAM1,VEGFA,VEGFC,VHLL,VPREB3,WASF2,WDR1,WNT11,WNT5A,WNT7A,WWC1,XCL1,XCL2,YES1,YWHAE,ZAP70,ZFAND5	TetrapodAncestor	166.594
GO.Biological.Process	GO:0045682	regulation.of.epidermis.development	142	7.251294e-171	9.366496e-167	6.596124e-169	1.540833e+0	ALOX15B,AQP3,ATOH1,BMP4,CBFB,CD109,CDH3,CTNNB1,CTSL,CYP27B1,DKK4,DLL1,ERRFI1,EZH2,FERMT1,FOXC1,FOXN1,FST,GAL,GDF3,GRHL2,H2AFY,H2AFY2,HES1,HES5,HEY2,HPSE,IL20,KDF1,KEAP1,KRT17,KRT36,KRT84,MAFF,MAFG,MSX2,MYCL,MYCN,MYSM1,NAB2,NCOA3,NME2,NOTCH1,OVOL2,PPARD,PRKCH,PTCH1,PTCH2,REG3A,REG3G,ROCK2,RUNX1,SERPINB13,SFN,SFRP4,SMAD4,SMO,SRSF6,SULT2B1,TGFB2,TMEM79,TNF,TP63,TRADD,VDR,WNT10B,WNT5A,ZFP36,ZFP36L1	TetrapodAncestor	166.028
GO.Biological.Process	GO:0031329	regulation.of.cellular.catabolic.process	143	1.016598e-169	1.313140e-165	9.182795e-168	1.272987e+0	AADAC,ABCD2,ABHD5,ACACB,ADAM8,ADAM9,ADRA2A,ADRB2,AGO2,AIFM1,AKT2,ALAD,AMER1,ANAPC1,ANAPC11,ANAPC16,ANAPC2,ANAPC4,ANAPC5,ANKIB1,APAF1,APOA1,APOA4,APOA5,APOC1,APOC3,APOE,ARAF,ARIH1,ATM,ATP13A2,ATP2B4,ATPIF1,ATRAID,AURKA,BAG6,BAX,BBS7,BCAP31,BPGM,BTG2,BTRC,CAV1,CAV3,CCAR2,CCDC22,CCNB1,CD81,CDC16,CDC20,CDC23,CDC26,CDC27,CDK1,CEBPA,CHFR,CIDEA,CLEC16A,CLU,CNOT1,CNOT8,CNR1,COMMD1,CPT1A,CSNK1A1,CSNK1D,CSNK1E,CTSC,CUL1,DAB2,DAB2IP,DACT1,DDA1,DDRGK1,DET1,DFFA,DISC1,DTX3L,DVL1,ECSCR,EFNA1,EGF,EGLN1,ENDOG,ENTPD5,EPHA4,ESRRB,ETFBKMT,EZR,FABP1,FBXL5,FBXO22,FBXO5,FBXW7,FGF21,FHIT,FMR1,FURIN,FZR1,GABARAPL2,GAPDHS,GBA,GIPC1,GNA12,GPD1,GPLD1,GSK3A,GTPBP1,HERPUD1,HIF1A,HMGB1,HP,HSF1,HSP90AB1,HSPBP1,HTR2A,HTT,IFNG,IGF1,IL10,IL1B,IL33,INS,IRS1,IRS2,ITCH,KCNE2,KEAP1,KHSRP,LAMP3,LAPTM4B,LATS1,LDLR,LONP2,LONRF1,LONRF2,LONRF3,LRIG2,LRP1,LRRK2,MAD2L1,MDM2,MLXIPL,MSN,MTM1,MTMR2,MTOR,MYLIP,N4BP1,NANOS1,NANOS2,NANOS3,NBAS,NELL1,NKD2,NOP53,NRDC,NUB1,NUDT15,OPHN1,P2RX7,PACSIN3,PANO1,PARK7,PBK,PDCL3,PFKFB1,PFKFB2,PFKFB3,PGAM1,PGAM2,PGAM4,PHKG2,PIAS1,PIK3CG,PINK1,PKD1,PKP1,PKP3,PLIN5,PLK1,PLK2,PLK3,PML,PNPLA2,PNPT1,POLR2G,PPARA,PPP1CB,PPP1R3B,PPP1R3D,PRICKLE1,PRKAA1,PRKAA2,PRKACA,PRKCD,PRKCG,PRKN,PRR5L,PSEN1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTEN,PTK2,PTK2B,PTPN1,PTPN3,PTTG1IP,RAD23A,RAD23B,RAPGEF3,RC3H1,RCHY1,RDX,RFWD2,RGN,RGP1,RHBDF1,RIC1,RNF114,RNF125,RNF128,RNF138,RNF139,RNF14,RNF144A,RNF144B,RNF166,RNF180,RNF19B,RNF217,RNF40,RPL11,RPL23,RPL5,RPS27A,RPS7,RYBP,SCARB1,SCO1,SDCBP,SECISBP2,SESN2,SGTA,SIRT2,SLIRP,SMAD7,SMARCC1,SMURF1,SNCA,SNX9,SOCS4,SOCS5,SPTLC1,SPTLC2,STUB1,SUFU,SUMO1,SUMO2,SVIP,TAF1,TAF9,TIGAR,TIMP1,TIMP2,TIMP3,TIMP4,TLK2,TMTC3,TNF,TNFAIP3,TNFRSF1B,TNRC6B,TNRC6C,TRIB1,TRIB2,TRIB3,TRIM39,TWIST1,TYSND1,UBC,UBE2C,UBE2D1,UBE2E1,UBE2V2,UBE3A,UBQLN1,UBQLN4,UBXN1,UCHL5,UFL1,UPF1,UQCC2,USP14,VCP,VPS11,VPS35,WDR91,WNT1,WNT10B,XBP1,ZC3H12A,ZC3HAV1,ZFAND2A,ZFP36,ZFP36L1,ZFP36L2	TetrapodAncestor	164.882
GO.Biological.Process	GO:0001837	epithelial.to.mesenchymal.transition	144	8.852179e-169	1.143436e-164	7.940528e-167	1.501298e+0	ADAM15,AMELX,BMP2,BMP7,CTNNB1,CUL7,DDX17,DDX5,DLG5,EFNA1,ENG,EOMES,EPB41L5,ERG,FAM83D,FGFR2,FOXF2,GSC,HAS2,HEY1,HEY2,HEYL,HGF,HIF1A,HMGA2,HNRNPAB,KBTBD8,KLHL12,LEF1,LOXL2,LOXL3,LRP6,MSX1,MSX2,NOG,NOLC1,NOTCH1,OLFM1,PDCD6,PEF1,RBPJ,RFLNB,RTN4,S100A4,SFRP1,SMAD4,SNAI1,SNAI2,SOX9,SPRY1,TCOF1,TGFB1,TGFB2,TGFBR1,TMEM100,TRIM28,WNT11,WNT16,WNT4,WNT5A,WNT8A	TetrapodAncestor	163.942
GO.Biological.Process	GO:0051129	negative.regulation.of.cellular.component.organization	145	2.780642e-168	3.591755e-164	2.477073e-166	1.192574e+0	ACAA2,ACD,ACE,ACTN4,ACVRL1,ADD1,ADIPOQ,AICDA,ANKRD27,ANTXR1,AP1AR,AP2M1,APC,APOA1,APOA2,APOBEC1,APOC1,APOC3,APOD,APOE,AR,ARAP1,ARF6,ARHGAP28,ARHGAP4,ARHGAP6,ARHGDIA,ARHGEF2,ARPIN,ARRB2,ASAP1,ASF1A,ATAD2,ATAD2B,ATG3,ATG5,ATM,ATXN2,AURKAIP1,AVIL,AVP,BAG4,BBS4,BCAS3,BCL11A,BCL2L1,BCOR,BECN1,BIRC2,BMP4,BMP7,BNIP3,BRCA1,BUB1,C15orf38-AP3S2,C16orf45,CAPG,CAPZA2,CAPZA3,CAPZB,CARM1,CARMIL1,CARMIL2,CAV1,CAV3,CBFA2T2,CCL21,CCNF,CCP110,CD300A,CD300LF,CDC42,CDK5,CDK5R1,CDK5RAP2,CENPF,CEP97,CERS2,CFLAR,CHEK1,CHMP2A,CHMP4A,CHMP4B,CIB1,CKAP2,CLASP1,CLASP2,CLEC16A,CLIP3,CLTC,CLU,CORO1A,CORO1B,CRBN,CRMP1,CRYAB,CSK,CTBP1,CTSZ,CXCL10,DAB1,DAB2,DACT1,DCC,DCP2,DDX3X,DFFA,DGUOK,DKK1,DLC1,DLG4,DMRT1,DMTN,DNAJA4,DNAJB1,DNAJB6,DNAJB8,DNAJC15,DNM1L,DNM2,DNMT3B,DPYSL3,DRAXIN,EFNA1,EFNA5,EFNB2,EFNB3,EIF4EBP1,EML2,EPHA3,EPHA4,EPHA7,EPHB2,EPS8,ERCC1,ERCC4,ESPL1,ESPN,EVI5L,EVL,EXOSC10,FBLN1,FBXO5,FEZ1,FEZ2,FGF13,FHOD3,FKBP4,FLCN,FOXP3,FRMD7,FSTL4,FXN,FZD9,GAK,GBA,GDI1,GFAP,GMFB,GMFG,GNL3L,GOPC,GSK3A,GSN,H2AFY,H3F3A,HDAC2,HDAC8,HDGFL3,HEY2,HGF,HIP1R,HMGB1,HNRNPC,HNRNPU,HRG,HSF1,HSPA2,HSPA8,HTRA2,IAPP,ID1,IFRD1,IGF1,IK,IKBKB,INPP5J,INPP5K,INS,IRAK3,ITGA3,ITM2C,JARID2,KANK1,KATNB1,KCNE1,KDM3A,KDM4C,KDM5A,KIAA0319,KIF25,KLHL22,LCMT1,LDLRAD4,LGALS1,LGALS3,LIF,LIG3,LIMA1,LINGO1,LMNA,LMO4,LMOD1,LMOD3,LPAR1,LRIG2,LRP1,LRP4,LRPAP1,LRRC15,LRRK2,LRRTM1,LRRTM2,LRSAM1,LYPD1,LYPLA1,LZTFL1,MAD1L1,MAD2L1,MAD2L2,MAG,MALSU1,MAP4,MAP4K4,MAP6D1,MAPRE1,MAPT,MCF2,MCTP1,MDM1,MDM2,MECP2,MEFV,MELTF,MET,MID1,MID1IP1,MKKS,MMP14,MORC1,MOS,MPV17L,MSH2,MTBP,MTF2,MTM1,MTMR2,MUL1,MYADM,NAA10,NANOS2,NAT10,NAV3,NBN,NECAB2,NFATC4,NGEF,NGFR,NLGN1,NLGN3,NLRC3,NOC2L,NOL3,NOP53,NPM1,NR1H2,NR1H3,NRP1,NUBP1,NUMB,OMA1,OMG,OPA1,OPRD1,OSM,OSTN,OTUB1,PACSIN2,PACSIN3,PAFAH1B1,PARK7,PARP1,PAX5,PEX14,PEX5,PFN1,PFN2,PFN4,PHF1,PHF2,PHLDB2,PICALM,PICK1,PID1,PIF1,PIH1D1,PINK1,PINX1,PKDCC,PLK1,PLK2,PLXNA3,PMEPA1,PMP22,POT1,PPARGC1A,PPFIA1,PPIF,PPP2R5A,PPP3CA,PRELID1,PRKAR1A,PRKCD,PRKCZ,PRKD1,PRKN,PROM2,PSEN1,PSMD10,PTEN,PTGER4,PTK2,PTN,PTPRG,PTPRO,PTPRS,PTTG1,PTTG2,PYDC2,RAB29,RAB7A,RAC1,RAD1,RAD21,RAD50,RAF1,RAP1GAP,RAP1GAP2,RAPGEF2,RAPGEF3,RBM14,RCC2,RDX,RGCC,RGMA,RHOQ,RIOK3,RIT2,RNF41,RNF6,ROBO2,ROCK2,RPL13A,RTN4,RTN4R,RTN4RL2,RUBCN,RUFY3,S1PR1,SACS,SCAMP5,SCFD1,SCIN,SDCBP,SDR16C5,SEC22B,SEMA3A,SEMA3G,SEMA5A,SETMAR,SHANK1,SIAH3,SIRT1,SIRT2,SIRT4,SKI,SLC25A5,SLC35F6,SLIT1,SLIT2,SLN,SLX1A,SLX1B,SLX4,SMAD4,SMARCB1,SMCR8,SMG6,SNAPIN,SNCA,SORL1,SOST,SPEF1,SPI1,SPOCK1,SPP1,SPRY2,SPTB,SPTBN2,SPTBN5,SRC,SRGAP2C,STAP1,STMN1,STMN2,STX1B,STXBP1,SVIP,SYNGAP1,SYT11,SYT4,TACSTD2,TBC1D30,TBC1D4,TBC1D7,TBCD,TBX20,TBX6,TERF1,TERF2,TERF2IP,TEX14,TFIP11,TGFB1,THBS1,THOC2,THRA,THY1,TIGAR,TINF2,TLR2,TLX2,TMBIM1,TMC8,TMEFF2,TMEM14A,TMEM59,TMEM67,TMOD1,TMOD2,TMOD3,TMOD4,TMSB4Y,TNF,TNFRSF8,TNKS,TNKS2,TNR,TOM1L1,TOP2A,TPR,TRAF3IP1,TRAK2,TRIAP1,TRIM37,TRIM9,TRIOBP,TRIP12,TRIP13,TRPC5,TRPC6,TSC2,TSPO,TTK,TUBB4A,TWF1,TWF2,TWIST1,UBE3A,UBQLN4,UBR5,UCN,ULK2,UNC119,VAT1,VIL1,VILL,VIM,VPS35,WAPL,WASF2,WASHC2C,WNT3,WNT3A,WNT5A,XAF1,XRCC1,XRCC5,XRN1,YWHAH,ZNF207,ZNF365,ZW10	TetrapodAncestor	163.445
GO.Biological.Process	GO:0072001	renal.system.development	146	8.724132e-168	1.126896e-163	7.718467e-166	1.234317e+0	ACAT1,ACE,ACTA2,ACVR2B,ADAMTS1,ADAMTS16,ADIPOQ,AGT,AGTR1,AGTR2,AHI1,AKR1B1,AMER1,ANGPT1,ANGPT2,APH1A,AQP1,AQP11,AQP2,ARG2,ARID5B,ARL3,BAG6,BASP1,BAX,BCL2,BCL2L11,BMP2,BMP4,BMP6,BMP7,BMPER,C1GALT1,C5orf42,CA2,CALB1,CAT,CD24,CD34,CDKN1C,CENPF,CEP55,CER1,CITED1,COL4A3,COL4A4,CTNNB1,CTSH,DACT2,DCHS1,DCHS2,DCN,DLG1,DLG5,DLL1,EFNB2,EGR1,EMX2,ENPEP,EPCAM,EPHA4,EPHA7,EYA1,FAT4,FGF1,FGF10,FGF2,FGFR1,FGFR2,FMN1,FOXC1,FOXC2,FOXF1,FOXJ1,FRAS1,FSTL3,GATA3,GCNT3,GCNT4,GDF11,GDNF,GLI2,GLI3,GPC3,GPR4,GREM1,GZF1,HAS2,HES1,HES5,HEYL,HNF1B,HPGD,ID3,IFT140,IFT20,IQGAP1,ITGA3,ITGA8,ITGB4,JAG1,JMJD6,KCNJ8,KIF26B,KIRREL3,KLF15,KLHL3,LAMA5,LGR4,LGR5,LHX1,LRP4,LRRK2,MAGI2,MEF2C,MME,MPST,MPV17,MTSS1,MYC,MYO1E,MYOCD,NF1,NFIA,NIPBL,NKX3-1,NLE1,NOG,NOTCH1,NOTCH3,NPHP3,NPHS1,NPHS2,NRP1,ODC1,OSR1,OVOL1,PAX2,PAX8,PBX1,PCSK5,PDGFB,PDGFRB,PECAM1,PKD1,PKD1L3,PKD2,PKHD1,PLCE1,PODXL,POU3F3,PRKX,PROM1,PROX1,PTCD2,PTCH1,PTPRO,PYGO2,RARA,RARB,RBP4,RDH10,REN,RET,RGN,ROBO2,RRM2B,SDC4,SEC61A1,SEC63,SFRP1,SGPL1,SIM1,SIX2,SLC34A1,SLIT2,SMAD2,SMAD4,SMAD5,SMAD7,SMO,SOX11,SOX17,SOX4,SOX8,SOX9,SPRY1,STAT1,STRA6,SULF2,TACSTD2,TBX18,TCF21,TEK,TFAP2A,TFAP2B,TGFB1,TGFB2,TGFBR1,TIPARP,TMED10,TNS2,TP63,TP73,TRAF3IP1,UMOD,UPK3A,VANGL2,VEGFA,WFS1,WNK4,WNT1,WNT11,WNT4,WNT5A,WNT6,WNT7B,WNT9B,WWTR1,ZBTB16,ZNF354A	TetrapodAncestor	162.948
GO.Biological.Process	GO:0048732	gland.development	147	2.947680e-167	3.807518e-163	2.590148e-165	1.210166e+0	AACS,ABCB4,ABL1,ACAT1,ADA,ADCYAP1,AKT2,ALDH1A3,ALOX15B,ANXA1,APLN,APOA1,AR,AREG,ARF6,ARG1,ARHGAP35,ARHGAP5,ARID5B,ASCL1,ASH1L,ASNS,ASXL1,ATM,ATP7B,AURKA,B4GALT1,BAAT,BCL11B,BCL2,BCL2L11,BMP2,BMP4,BMP7,BMPR1A,BRAF,BSX,BTRC,C8orf22,CAPN1,CAV1,CCDC40,CCKBR,CCL11,CCND1,CDC42,CDH1,CDKN1C,CDO1,CEBPA,CEBPB,CEBPG,CITED2,CLCN2,CLDN1,COBL,CPB2,CPS1,CREB1,CRIP1,CRKL,CSF1,CSF1R,CSNK2A1,CSNK2A2,CSNK2B,CTNNB1,CUL3,CYP19A1,CYP1A1,DBP,DDR1,DHODH,DKK3,DNAAF1,DRD2,DUOX2,E2F7,E2F8,EDA,EDAR,EGF,EGFR,ELF3,ELF5,EPHA2,EPHB3,EPHX1,ERBB4,ESR1,ESRP2,ETS1,EZH2,FA2H,FADD,FASN,FEM1B,FGF10,FGF7,FGFR1,FGFR2,FKBP4,FOXA1,FOXC1,FOXE1,FOXF1,FOXN1,FPGS,FRS2,FSTL3,GATA2,GATA3,GATA6,GCM2,GFER,GHRH,GHRHR,GLI2,GLI3,GNPNAT1,GPAT4,HAMP,HAND2,HES1,HESX1,HGF,HHEX,HIF1A,HLX,HMGCL,HMGCS1,HMOX1,HNF1B,HNRNPD,HRH2,ID2,ID4,IGF2R,IGFBP5,IGSF3,IHH,IL10,IL6,INSM1,IRF6,IRS2,ISL1,ITGA2,JAK2,JARID2,JUN,KALRN,KDM5B,KRAS,KRT76,LAMA5,LATS1,LBH,LEF1,LMO4,LRP5,LSR,MAD1L1,MAFB,MAN2A1,MAPK1,MAPK3,MDK,MPST,MSN,MSX1,MSX2,NCOA1,NEURL1,NF1,NFIB,NKX2-3,NKX2-5,NKX3-1,NME1,NOG,NOTCH1,NOTCH4,NPHP3,NR0B1,NRG1,NRG3,NRP1,ONECUT1,OTC,OXTR,PAM,PAX8,PBX1,PCNA,PGR,PHF2,PIK3CA,PITX1,PITX2,PKD1,PKD2,PKM,PLAG1,PLXNA1,PLXND1,PML,PNPT1,POLB,POU1F1,POU3F2,PRKDC,PRL,PRLR,PRMT5,PROC,PROP1,PROX1,PSAP,PSAPL1,PSEN1,PTCD2,PTCH1,PTEN,PTF1A,PTN,PTPN3,PYGO2,QDPR,RAF1,RAG1,RAP1A,RARA,RARG,RB1CC1,RBPJ,RELA,RGN,RHBDD3,RIPK3,RPS16,RPS6KA1,RXRA,SCRIB,SEC63,SEMA3A,SEMA3C,SERPINA5,SERPINB5,SERPINC1,SERPINE2,SFRP1,SLC29A1,SLC46A2,SLC6A3,SLC9A3R1,SMAD4,SMARCC1,SMO,SOCS2,SOD1,SOSTDC1,SOX10,SOX2,SOX3,SOX9,SRC,SRD5A1,SRF,SRSF1,SRSF5,STAT6,STRA6,SULF2,TBX1,TBX19,TBX2,TBX3,TCF21,TDGF1,TFCP2L1,TG,TGFB1,TGFB2,TGFBR1,TGFBR2,TGM2,THRA,TNC,TNF,TNFRSF11A,TNFSF11,TP63,TPH1,TSPO,TYMS,TYR,UBE3A,UCP2,UGT1A1,UMPS,UPF2,UPRT,USF2,VDR,VEGFA,VTN,WDR35,WDR77,WLS,WNT1,WNT10A,WNT11,WNT3,WNT3A,WNT4,WNT5A,WNT7B,XBP1,XDH,ZBTB1,ZDHHC21,ZIC3,ZNF703	TetrapodAncestor	162.419
GO.Biological.Process	GO:0009057	macromolecule.catabolic.process	148	9.249075e-167	1.194703e-162	8.072318e-165	1.180656e+0	ABHD12,ABHD13,ABHD17A,ABHD17B,ABHD17C,ABTB1,ABTB2,ACAN,ACE,ACE2,ADAMTS12,ADAMTS7,ADAMTS9,ADRM1,AGL,AGO1,AGO3,AGO4,AGRN,AMBP,AMER1,AMFR,ANAPC1,ANAPC11,ANAPC16,ANAPC2,ANAPC4,ANAPC5,ANKIB1,ANKZF1,AP2A1,AP2A2,AP2B1,AP2M1,AP2S1,APC,APOB,APOE,ARIH1,ARNTL,ARRB1,ARRB2,ATE1,ATM,ATXN3,AUP1,AURKA,AURKB,BACE1,BACE2,BAG6,BAP1,BCAN,BECN1,BECN2,BFAR,BGN,BIRC2,BNIP3,BNIP3L,BRSK2,BTBD11,BTBD2,BTBD3,BTBD6,BTBD9,BTRC,C17orf97,C2orf40,CACUL1,CALM1,CAPN1,CAPN2,CASC3,CASP3,CASP8,CBL,CBLC,CCDC47,CCIN,CCNB1,CCNF,CD2AP,CD44,CDC16,CDC20,CDC23,CDC26,CDC27,CDC34,CDK1,CDK5,CECR2,CEMIP,CHEK2,CHFR,CHIA,CHID1,CHIT1,CHMP4B,CHMP4C,CHP1,CLN3,CLN6,CLN8,CLPP,CLPX,CLTA,CLTC,CNOT1,CNOT10,CNOT11,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT8,COPS3,CPA2,CPVL,CRBN,CSDE1,CSNK1A1,CSPG4,CTIF,CTNNB1,CTSA,CTSB,CTSC,CTSD,CTSE,CTSH,CTSL,CTSO,CTSW,CTSZ,CUL1,CUL2,CUL3,CUL4A,CUL5,CUL7,CUL9,DAB2IP,DCN,DCP2,DCPS,DCST1,DDB1,DDX5,DEDD2,DENND3,DERL1,DERL2,DERL3,DFFA,DFFB,DIS3L2,DNA2,DNAJB12,DNAJC10,DNASE1,DNASE1L1,DNASE1L2,DNASE1L3,DNASE2,DROSHA,DTX3L,DXO,DZIP3,EDC3,EDC4,EDEM1,EDEM2,EDEM3,EIF3E,EIF4A1,EIF4A2,EIF4A3,EIF4E,ELOC,ENDOG,ENPEP,ENSG00000258677,ENSG00000261884,ENSG00000265303,ENSG00000282246,ERCC8,ERLIN1,ERLIN2,ERN1,ERN2,ETF1,EXOSC1,EXOSC10,EXOSC2,EXOSC3,EXOSC4,EXOSC5,EXOSC6,EXOSC7,EXOSC9,FAF1,FAF2,FBXL12,FBXL15,FBXL19,FBXL2,FBXL22,FBXL3,FBXL5,FBXL7,FBXO10,FBXO15,FBXO18,FBXO2,FBXO21,FBXO22,FBXO31,FBXO39,FBXO4,FBXO44,FBXO45,FBXO6,FBXO7,FBXO8,FBXW11,FBXW5,FBXW7,FEN1,FGF2,FMOD,FOXRED2,FUCA1,FZR1,G6PC,GAA,GET4,GID4,GLB1,GNS,GPC1,GPC2,GPC3,GPC4,GPC5,GPC6,GSK3A,GSPT1,GTSE1,GUSB,GYG1,GYG2,GZMA,H1F0,HACE1,HBS1L,HECTD3,HECW1,HECW2,HERC2,HERPUD1,HEXA,HM13,HMGB1,HMGB2,HMMR,HNRNPD,HPSE,HPSE2,HSP90B1,HSPA5,HSPG2,HTRA2,IDE,IDS,IDUA,ISG15,ISG20,ITCH,JKAMP,KAT5,KBTBD4,KBTBD8,KCTD13,KCTD17,KCTD2,KCTD21,KCTD5,KCTD6,KEAP1,KERA,KHSRP,KIAA0368,KIF16B,KLHL15,KLHL2,KLHL20,KLHL25,KLHL29,KLHL3,KLHL42,KLHL8,KPNA1,KPNB1,LDLR,LGMN,LIN28A,LIN28B,LNPEP,LNX1,LONP1,LONP2,LRSAM1,LSM1,LSM3,LSM5,LSM7,LUM,LYG1,LYG2,LYPLA1,LYPLA2,LYPLAL1,MAD2L1,MAEA,MAGEC2,MAGOH,MAGOHB,MAN1B1,MARCH6,MDM2,METTL14,METTL3,MGAM,MLH1,MMP20,MRTO4,MTA1,MTOR,MTPAP,MUS81,MVB12A,MYLIP,NANOS2,NAPSA,NBAS,NCBP1,NCBP2,NEDD4L,NEDD8,NEU4,NHLRC1,NOCT,NOTUM,NR1D1,NSFL1C,NTAN1,NUB1,NUDT16,OGN,OMA1,OMD,OS9,OTUD7A,OTUD7B,OVGP1,P2RX7,PABPC4,PAIP1,PAN2,PAN3,PAPD4,PARN,PATL1,PCBP2,PCID2,PCNP,PCYOX1,PCYOX1L,PDCD6IP,PDE12,PELO,PGA3,PGA5,PGC,PGLYRP1,PGLYRP2,PGLYRP3,PGLYRP4,PGM2,PGM2L1,PHKA1,PHKA2,PHKB,PHKG1,PHKG2,PINK1,PJA1,PLAA,PLG,PLK1,PMAIP1,PML,PNLDC1,PNPT1,PNRC1,PNRC2,POLR2D,POLR2G,POMT1,POMT2,PPP1R8,PPP2CB,PPP2R2A,PPP2R5C,PPT1,PRELP,PRKN,PRPF18,PRPF19,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTPN23,PTTG1,PYGB,PYM1,RAB12,RAB7A,RAD23A,RAD23B,RANBP2,RANBP3,RANBP3L,RBCK1,RBM8A,RC3H1,RCHY1,RFFL,RFWD2,RGPD4,RHBDD1,RIPK1,RLIM,RMND5A,RMND5B,RNASEH1,RNASEH2A,RNASEH2B,RNASEH2C,RNASET2,RNF103,RNF11,RNF115,RNF121,RNF122,RNF125,RNF126,RNF128,RNF139,RNF14,RNF144A,RNF144B,RNF145,RNF146,RNF168,RNF175,RNF181,RNF185,RNF19B,RNF20,RNF213,RNF216,RNF217,RNF222,RNF24,RNF34,RNF38,RNF4,RNF40,RNF41,RNF43,RNF44,RNF5,RNF6,RNF7,RNF8,RNH1,RNPS1,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL23,RPL23A,RPL24,RPL27,RPL28,RPL29,RPL3,RPL30,RPL31,RPL34,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL5,RPL6,RPL7,RPL7A,RPL8,RPLP0,RPLP2,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS17,RPS18,RPS20,RPS21,RPS23,RPS24,RPS25,RPS26,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS4X,RPS5,RPS6,RPS7,RPS8,RPSA,SAMD4A,SAMD4B,SCPEP1,SDC2,SDC4,SDF2L1,SEC61B,SEL1L,SETMAR,SGSH,SGTA,SH3GLB1,SHARPIN,SIAH1,SIAH2,SIAH3,SIDT2,SIRT1,SIRT2,SKIV2L2,SKP2,SLC9A1,SLFN14,SMG1,SMG5,SMG6,SMG7,SMG8,SMURF1,SMURF2,SND1,SNF8,SOCS6,SPACA3,SPATA18,SPO11,SPOP,SPOPL,SQSTM1,STAB2,STBD1,STK31,STT3B,STUB1,SYVN1,TAF1,TATDN1,TBL1X,TBL1XR1,TCIRG1,TGFB1,TGFB1I1,THRAP3,TMEM129,TMEM199,TMEM2,TMEM67,TMUB1,TNFAIP1,TNFAIP3,TNKS1BP1,TOLLIP,TOM1L1,TOPORS,TOR1A,TP53,TP53INP2,TPP1,TRAF2,TRIM13,TRIM24,TRIM25,TRIM32,TRIM58,TRIM72,TRIM9,TRIP12,TRPC4AP,TSG101,TTC3,TTC37,UBA1,UBA6,UBA7,UBAP1,UBAP1L,UBC,UBE2A,UBE2C,UBE2D1,UBE2D2,UBE2D3,UBE2E1,UBE2G2,UBE2H,UBE2I,UBE2J1,UBE2J2,UBE2L3,UBE2L5P,UBE2L6,UBE2N,UBE2R2,UBE2S,UBE2W,UBE3A,UBE4A,UBQLN1,UBR1,UBR2,UBR4,UBR5,UBXN1,UBXN11,UBXN2B,UBXN4,UBXN6,UBXN8,UCHL1,UCHL5,UFD1,UGGT1,UHRF1,UPF1,UPF2,UPF3A,USE1,USP1,USP10,USP11,USP13,USP14,USP15,USP16,USP17L3,USP17L30,USP18,USP2,USP20,USP21,USP22,USP24,USP25,USP26,USP28,USP3,USP31,USP32,USP35,USP36,USP37,USP38,USP40,USP41,USP42,USP46,USP47,USP48,USP49,USP50,USP7,USP8,USP9X,USP9Y,UVRAG,VCAN,VCP,VHLL,VLDLR,VPS25,VPS28,VPS36,VPS4A,VPS4B,WDR61,WDR81,WFS1,WNT1,WWP1,WWP2,WWTR1,XBP1,XRN1,YME1L1,YOD1,ZC3H12A,ZCCHC11,ZCCHC6,ZFP36,ZFP36L1,ZFP36L2,ZHX2,ZMPSTE24,ZNRF1,ZNRF2,ZNRF3,ZNRF4,ZPR1	TetrapodAncestor	161.923
GO.Biological.Process	GO:0030029	actin.filament-based.process	149	9.393207e-167	1.213321e-162	8.143091e-165	1.215743e+0	ABI1,ABI2,ABL1,ABLIM2,ABLIM3,ABR,ACTN1,ACTN4,ACTR2,ACTR3,ACTR3B,ACTR3C,ADD1,ADRA2A,AIF1,ALDOA,ALKBH4,AMOT,ANK2,ANKRD1,ANTXR1,ANXA1,AQP1,ARAP1,ARF1,ARF6,ARHGAP12,ARHGAP25,ARHGAP26,ARHGAP35,ARHGAP6,ARHGEF11,ARHGEF17,ARHGEF2,ARPC1A,ARPC1B,ARPC2,ARPC4,ARPC4-TTLL3,ARPC5,ARRB1,ATP1A1,ATXN3,AUTS2,BAIAP2L2,BCAR1,BCL2,BCL6,BCR,BIN3,BMP10,BRSK2,CACNA1C,CACNA1D,CACNA1G,CACNA2D1,CACNB2,CALR,CAMK2D,CAP1,CAP2,CAPN10,CAPZB,CARMIL1,CARMIL2,CASQ1,CASQ2,CATIP,CAV3,CAVIN3,CCDC155,CCL11,CD2AP,CDC42,CDC42BPA,CDC42BPB,CDC42BPG,CDC42EP2,CDK5,CFL1,CFL2,CFLAR,CLRN1,CNN1,CNN3,COBL,CORO1A,CORO1B,CORO2B,CORO6,CSRP3,CTNNA1,CTTN,CUL3,CXADR,CXCL1,CYTH2,DAAM1,DAAM2,DBN1,DES,DIAPH1,DIAPH2,DIAPH3,DLC1,DLG1,DMD,DMTN,DNAJB6,DOCK2,DPYSL3,DSTN,DTNBP1,EHD2,ELMO1,EMP2,ENSG00000284292,EPB41,EPB41L1,EPB41L2,EPB41L3,EPB41L4A,EPB41L4B,EPB41L5,EPS8,ESPN,ESPNL,EVL,EZR,F11R,FAT1,FER,FGD1,FGD2,FGD3,FGD4,FGD5,FGF10,FGF12,FGF7,FHL3,FHOD3,FLII,FLNA,FLNB,FMN1,FMN2,FMNL1,FMNL2,FMNL3,FNBP1L,FOXJ1,FRMD3,FRMD5,FRMD6,FRY,FRYL,FSCN1,FSCN3,GAB1,GAS2L3,GDPD2,GHSR,GJA1,GJC1,GMFG,GPD1L,GPR65,GSN,HCLS1,HSP90B1,IGSF22,IKBKB,INF2,INPP5K,INSRR,IQSEC2,IQSEC3,ITGB1,ITGB5,ITPKA,JAK2,JMY,KCNA5,KCNE1,KCNE2,KCNE5,KCNH2,KCNJ2,KCNJ3,KCNJ5,KCNJ8,KCNN2,KCNQ1,KCTD13,KLHL1,KLHL17,KPTN,KRAS,KRT19,LCP1,LDB3,LIMA1,LIMCH1,LIMK1,LMOD1,LMOD3,LURAP1,MAD2L2,MAPKAP1,MARCKS,MEF2A,MICAL1,MICAL3,MINK1,MKLN1,MLPH,MOB2,MOBP,MSRB2,MTSS1,MYBPC1,MYBPC2,MYBPC3,MYBPH,MYH10,MYH14,MYH3,MYH6,MYH7,MYH9,MYL1,MYL3,MYL6,MYL6B,MYLK3,MYO18A,MYO1B,MYO1E,MYO6,MYO9B,MYOM2,MYOM3,MYOZ3,MYPN,MYRIP,NCK1,NCK2,NCKAP1L,NEB,NEBL,NEDD4L,NEDD9,NF1,NF2,NISCH,NKX2-5,NPHP1,NPHP4,NPHS2,NRP1,NUAK2,NUP155,OBSCN,OPHN1,PACSIN2,PAFAH1B1,PAK1,PAK2,PAK4,PAK5,PALLD,PARVB,PARVG,PAWR,PDCD6IP,PDGFA,PDGFRB,PDLIM3,PDLIM4,PDLIM7,PDPK1,PDPN,PDXP,PFN1,PFN2,PFN3,PHACTR1,PHACTR4,PIP5K1A,PIP5K1C,PKP2,PLA2G1B,PLEK,PLEK2,PLS1,PLS3,POF1B,PPARGC1B,PREX1,PRKAR1A,PRKCI,PRKCZ,PRKG1,PROX1,PTK2B,PTK7,PTPN1,RAB13,RAC1,RAC2,RAC3,RACGAP1,RALA,RAP1GDS1,RAP2A,RFLNA,RFLNB,RHOD,RHOG,RHOJ,RHOQ,RHOU,RICTOR,RND1,RND3,ROCK2,RUFY3,RYR2,S1PR1,SBK2,SCIN,SCN1B,SCN2B,SCN3B,SCN4B,SCN5A,SDAD1,SDCBP,SELE,SH3BP1,SHC1,SHROOM4,SIPA1L1,SLC9A1,SLC9A3R1,SNTA1,SORBS1,SORBS2,SORBS3,SPIRE1,SPIRE2,SPTBN5,SRC,SRF,SRGAP2,SSH2,STRIP1,SUN2,SYNE2,TAOK2,TBCK,TESK2,TLN1,TMOD1,TMOD2,TMOD3,TMOD4,TMSB4Y,TNF,TNFAIP1,TNIK,TNNC1,TNNC2,TNNI2,TNNI3,TNNT1,TNNT2,TNNT3,TNXB,TPM2,TPM3,TPM4,TRIM32,TRIOBP,TRIP10,TRPM7,TTC17,TTN,USH1C,VASP,VIL1,VIM,WASF2,WDR1,XIRP1,ZYX	TetrapodAncestor	161.916
GO.Biological.Process	GO:0051223	regulation.of.protein.transport	150	2.491640e-166	3.218451e-162	2.145634e-164	1.177986e+0	AACS,ABAT,ABCC8,ABL1,ABLIM3,ACHE,ACSL3,ACSM6,ADAM8,ADAM9,ADCY5,ADIPOQ,ADORA2A,ADRA2A,ADRA2C,AGER,AGTR2,AKT2,ALOX15B,ANGPT1,ANK3,ANKRD1,ANO1,ANXA1,ANXA4,APC2,APOA1,APOA2,APOD,APP,ARF1,ARFIP1,ARG2,ARL2,ARL2BP,ARNTL,ARRB1,ATG13,ATG5,ATP13A2,ATPIF1,AXIN2,B3GAT3,BAD,BAG4,BAMBI,BANK1,BAP1,BARD1,BCAP31,BCAS3,BCL3,BLK,BMP4,BMP6,BMP7,BMP8A,BMPR1A,BNIP3L,BRSK2,C1QTNF12,C1QTNF3,C2CD2L,C2CD5,C5,C8orf4,CABP1,CACNA1A,CACNA1C,CACNA1D,CACNA1E,CACNA2D2,CADM1,CAMK1,CAPN10,CARD16,CARD17,CARD18,CARTPT,CASP1,CASP5,CASR,CCDC22,CCL19,CCL2,CCL3,CCL5,CCR7,CD14,CD2,CD27,CD274,CD34,CD36,CD38,CD40,CD58,CDC42,CDH1,CDK1,CDK16,CDK5,CDK5R1,CDKL2,CDKN1A,CEMIP,CFTR,CHERP,CHIA,CHP1,CHRM1,CHUK,CIB1,CIDEA,CLEC4E,CLEC6A,CLEC9A,CNR1,CNST,CPT1A,CRTAM,CSF1R,CSF3,CSK,CSNK2A2,CTDSPL2,CYB5R1,DAB2,DAB2IP,DACT1,DACT3,DDX58,DERL2,DERL3,DHX9,DISP1,DMAP1,DMTN,DNAJA1,DNAJC1,DNAJC27,DNM1L,DOC2B,DPH3,DRD2,DRD3,DRD4,DTWD2,DYRK2,ECT2,EDA,EDAR,EDEM1,EDEM2,EFNA5,EGF,EGFR,ELMOD1,ENSG00000173366,EPHA5,ERBB2,ERBB4,ERP29,EXPH5,EZR,F2,F2R,F2RL1,FAF1,FAM20B,FAM3D,FAM89B,FBXW11,FBXW7,FCN1,FERMT1,FFAR1,FFAR2,FFAR4,FGG,FGR,FIS1,FKBP1B,FLNA,FN1,FOXA2,FOXP3,FZD1,FZD5,FZD7,G3BP2,GAPDH,GAPVD1,GAS6,GATA3,GCC2,GCK,GDI1,GHSR,GIP,GIPR,GJA1,GLI3,GLP1R,GLUD1,GLUL,GNAQ,GOLPH3,GOPC,GPAM,GPER1,GPHA2,GPLD1,GPR68,GREM1,GSDMD,GSK3A,GTSE1,HAVCR2,HAX1,HCLS1,HDAC3,HES1,HHAT,HIF1A,HMGB1,HMGCR,HMGN3,HMHB1,HNF4A,HNMT,HPCA,HPS4,HSP90AB1,HSPA8,HTR2B,HTRA2,ICA1,ICE1,IDH2,IFI27,IFNA2,IFNAR1,IFNG,IFNL3,IGF1,IL10,IL12B,IL13,IL17A,IL17F,IL17RA,IL17RB,IL17RC,IL18,IL18R1,IL1A,IL1B,IL1R2,IL1RAP,IL1RL1,IL2,IL23A,IL26,IL33,IL36RN,IL5,IL6,INHBB,INPP5K,INS,IPO5,IRF3,IRS1,IRS2,ISL1,ITGAM,ITGAX,ITPR1,ITPR2,ITPR3,JAGN1,JAK2,JUP,KANK1,KARS,KCNA5,KCNB1,KCNC2,KCNE1,KCNG2,KCNJ11,KCNN3,KCNS3,KEAP1,KIF20B,KIF5B,KRT20,LACRT,LCP1,LEP,LEPROT,LGALS9,LGR4,LITAF,LLGL2,LPL,LRP1,LRP5,LRRC32,LRRK2,LYN,LYPLA1,MAP4K4,MAPK1,MAPK11,MAPK14,MAPK3,MARCKS,MBTPS1,MCU,MDFI,MDM2,MFF,MIEF1,MIEF2,MIF,MIS18A,MMP12,MPC2,MRGPRE,MTNR1B,MTOR,MYBPC1,MYO18A,MYO1C,MYRIP,NDEL1,NDFIP1,NDFIP2,NDUFAF2,NEUROD1,NF1,NKX6-1,NLRP1,NLRP10,NLRP2,NLRP7,NMUR1,NNAT,NOL3,NOS2,NOV,NPEPPS,NPFF,NR0B2,NR1D1,NR1H2,NR1H3,NR1H4,NRG1,NRXN1,NUCB1,NUP54,NUP58,NUP62,NUTF2,OAZ1,OAZ2,OGG1,OPRM1,OR51E2,ORM1,ORM2,OS9,OXCT1,P2RX7,P3H1,PAEP,PAK1,PAM,PANX1,PARK7,PARL,PARP1,PARP10,PBLD,PCK2,PCM1,PCNT,PDCD10,PDCD5,PDE2A,PDE8B,PEMT,PER2,PFKFB2,PFKL,PHPT1,PIK3C3,PIK3R1,PIK3R2,PIM3,PINK1,PKD1,PKD2,PKDCC,PKIA,PKIG,PLA2G1B,PLA2G6,PLK3,PML,POLR3A,PPARD,PPP3CA,PPP3CB,PRDX1,PRELID3A,PRKACA,PRKCA,PRKCD,PRKCE,PRKCZ,PRKN,PRR5L,PSEN1,PSMB7,PSMD10,PSMD8,PSMD9,PTGER4,PTPN1,PTPN11,PTPN14,PTPN22,PTPN23,PYCARD,PYDC1,PYDC2,RAB11FIP1,RAB11FIP5,RAB23,RAB29,RAB8A,RAC2,RAP1A,RAPGEF3,RASGRP1,RBCK1,RBM22,RBP4,RBPMS,REST,RFX3,RFX6,RGCC,RHBDD3,RHBDF1,RHBDF2,RHOU,RIPK2,RIPOR1,RNF31,RPH3AL,RPL28,RSAD2,RUFY3,RUVBL1,SAA1,SCAMP5,SCFD1,SEC16B,SELENOI,SELENOK,SEMA5A,SERGEF,SERP1,SFN,SFRP1,SFRP2,SFRP5,SH3GLB1,SH3TC2,SIAH3,SIDT2,SIRT1,SIRT3,SIRT4,SLC16A1,SLC25A5,SLC25A6,SLC2A1,SLC2A2,SLC30A8,SLC35D3,SLC51B,SLC8B1,SLC9A3R1,SLC9B2,SMAD4,SMO,SNAI2,SNAP25,SNIP1,SNX12,SOCS1,SORL1,SOX4,SP100,SPHK1,SPPL3,SRC,SRCIN1,SREBF1,SREBF2,SRI,SSC5D,SSTR5,STARD7,STOM,STX1A,STX4,STXBP4,STXBP5,STXBP5L,SUFU,SULF2,SVIP,SYBU,SYK,SYT11,SYT4,SYT7,SYT9,SYTL4,TARDBP,TBC1D10C,TDRD12,TENM1,TFAP2B,TGFB1,TGFB2,TGFBR1,THRA,TIAM1,TLR1,TLR10,TLR2,TLR3,TLR4,TLR5,TLR6,TLR9,TM7SF3,TM9SF4,TMBIM6,TMEM110,TMEM173,TMEM27,TMEM30B,TNF,TNFRSF14,TNFRSF21,TNFRSF4,TNFRSF9,TNFSF14,TOMM7,TONSL,TP53,TPR,TRAF2,TRAF6,TRIM28,TRIM6,TRIP6,TRPM4,TSG101,TSGA13,TTN,TWIST1,TXN,U2AF1,U2AF2,UBAC2,UBE2D3,UBE2G2,UBE2J1,UBE2J2,UBE2L3,UBL5,UBR5,UCN3,UCP2,UGCG,UHMK1,UNC13B,UQCC2,USP36,UTS2,VAMP2,VEGFC,VPS11,VPS28,VPS35,VSNL1,VTCN1,WBP11,WDR46,WDR75,WLS,WNT3A,WNT5A,WWP2,WWTR1,XBP1,XPO4,XPO5,YOD1,YWHAE,ZBED3,ZBTB17,ZC3H12A,ZDHHC8,ZIC1,ZPR1	TetrapodAncestor	161.492
GO.Biological.Process	GO:0031331	positive.regulation.of.cellular.catabolic.process	151	1.592320e-165	2.056800e-161	1.362119e-163	1.324511e+0	AADAC,ABCD2,ABHD5,ADAM8,ADAM9,ADRA2A,ADRB2,AGO2,AKT2,AMER1,ANAPC1,ANAPC11,ANAPC16,ANAPC2,ANAPC4,ANAPC5,ANKIB1,APOA1,APOA4,APOA5,APOE,ARIH1,ATM,ATPIF1,AURKA,BAX,BBS7,BCAP31,BTG2,BTRC,CAV1,CAV3,CCDC22,CCNB1,CD81,CDC16,CDC20,CDC23,CDC26,CDC27,CDK1,CEBPA,CHFR,CLU,CNOT1,CNOT8,CPT1A,CSNK1A1,CSNK1D,CSNK1E,CTSC,CUL1,DAB2,DAB2IP,DACT1,DDRGK1,DET1,DISC1,DTX3L,DVL1,ECSCR,EGF,ENDOG,ENTPD5,ESRRB,EZR,FABP1,FBXL5,FBXO22,FBXO5,FBXW7,FGF21,FMR1,FURIN,FZR1,GAPDHS,GBA,GPD1,GPLD1,GTPBP1,HERPUD1,HIF1A,HMGB1,HSF1,HSPBP1,HTR2A,HTT,IFNG,IGF1,IL1B,IL33,INS,IRS1,IRS2,ITCH,KCNE2,KEAP1,KHSRP,LDLR,LONRF1,LONRF2,LONRF3,LRP1,LRRK2,MAD2L1,MDM2,MLXIPL,MSN,NANOS1,NANOS2,NANOS3,NKD2,NOP53,NRDC,NUB1,P2RX7,PACSIN3,PFKFB1,PFKFB2,PFKFB3,PHKG2,PIAS1,PLIN5,PLK1,PLK2,PLK3,PNPLA2,PNPT1,POLR2G,PPARA,PRICKLE1,PRKAA1,PRKAA2,PRKCD,PRKN,PRR5L,PSEN1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTEN,PTK2,PTK2B,PTPN1,PTTG1IP,RAD23A,RAPGEF3,RC3H1,RCHY1,RDX,RFWD2,RGN,RNF114,RNF125,RNF128,RNF138,RNF139,RNF14,RNF144A,RNF144B,RNF166,RNF180,RNF19B,RNF217,RNF40,RPS27A,SESN2,SGTA,SIRT2,SMAD7,SMURF1,SNCA,SNX9,SOCS4,SOCS5,SPTLC1,SPTLC2,STUB1,SUMO1,SUMO2,TAF1,TMTC3,TNF,TNFAIP3,TNFRSF1B,TNRC6B,TNRC6C,TRIB1,TRIB2,TRIB3,TWIST1,UBC,UBE2C,UBE2D1,UBE2E1,UBE2V2,UBQLN1,UPF1,UQCC2,VCP,VPS11,VPS35,XBP1,ZC3H12A,ZC3HAV1,ZFAND2A,ZFP36,ZFP36L1,ZFP36L2	TetrapodAncestor	160.687
GO.Biological.Process	GO:0006935	chemotaxis	152	3.243268e-165	4.189329e-161	2.756138e-163	1.188147e+0	ACKR2,ACKR3,ACKR4,ADAM8,ADGRE2,AGTR1,ALCAM,ALKBH1,AMOT,ANGPT1,ANO6,ANOS1,ANXA1,APBB2,APOA1,APP,ARHGAP35,ARHGEF16,ARRB2,ARTN,ARX,ATOH1,B3GNT2,BCAR1,BCL11B,BDNF,BMP4,BMP7,BMPR1B,BOC,C3AR1,C5,CCL1,CCL11,CCL13,CCL14,CCL15,CCL15-CCL14,CCL16,CCL17,CCL18,CCL19,CCL2,CCL21,CCL22,CCL23,CCL27,CCL28,CCL3,CCL3L3,CCL4,CCL4L2,CCL5,CCL7,CCL8,CCR1,CCR2,CCR3,CCR4,CCR5,CCR6,CCR7,CCR8,CCR9,CCRL2,CDH4,CDK5,CDK5R1,CH25H,CHGA,CHL1,CKLF,CMKLR1,CMTM1,CMTM2,CMTM3,CMTM4,CMTM5,CMTM6,CMTM7,CMTM8,CNR2,CNTN2,CNTN4,COLEC10,CORO1A,CORO1B,CREB1,CREB3,CRMP1,CSF1R,CSF3R,CX3CL1,CX3CR1,CXADR,CXCL1,CXCL10,CXCL11,CXCL13,CXCL14,CXCL16,CXCL2,CXCL3,CXCL5,CXCL6,CXCL8,CXCL9,CXCR1,CXCR2,CXCR3,CXCR4,CXCR5,CXCR6,CYR61,DAB1,DCC,DLX5,DOCK2,DOCK4,DOK1,DOK2,DOK4,DOK5,DOK6,DPYSL2,DPYSL4,DPYSL5,DRAXIN,DVL1,ECSCR,EDN2,EDN3,EDNRB,EFNA1,EFNA3,EFNA4,EFNA5,EFNB1,EFNB2,EFNB3,EGR2,EGR3,ELMO2,ENAH,ENPP2,ENSG00000251246,EPHA2,EPHA4,EPHA5,EPHA7,EPHA8,EPHB1,EPHB2,EPHB3,ERBB2,ETV1,EVL,EXT1,EZR,FAM129B,FCER1G,FER,FES,FEZ1,FEZ2,FEZF1,FFAR2,FGF10,FGF2,FGF7,FLRT2,FLRT3,FLT1,FOSL1,FOXG1,FRS2,FZD3,GAB1,GAB2,GAP43,GAS6,GATA3,GBF1,GBX1,GBX2,GDNF,GFRA1,GFRA2,GFRA3,GFRA4,GLI2,GLI3,GPC1,GPNMB,GPR183,GPR32,GPR33,GRB10,GRB2,GRB7,HBEGF,HGF,HMGB1,HMGB2,HRAS,HRG,HSD3B7,IFNG,IL10,IL16,IL17RA,IL17RC,IL1B,IL4,IL6,IL6R,IRS2,ISL1,ISPD,ITGA1,ITGA9,ITGAV,ITGB2,JAML,KIF5A,KIF5B,KIF5C,KIRREL1,KLF7,KRAS,L1CAM,LAMA2,LBP,LECT2,LEF1,LGALS3,LGALS9,LHX1,LHX2,LHX4,LMX1A,LPAR1,LSP1,LTB4R2,LYPLA2,MAPK1,MAPK14,MAPK3,MATN2,MET,MIF,MOSPD2,NCAM1,NCKAP1L,NECTIN1,NEO1,NFASC,NFIB,NGFR,NOG,NOV,NPHS1,NR4A1,NR4A3,NRAS,NRG1,NRG3,NRP1,NRP2,NRTN,NRXN1,NRXN3,NTF3,NTN3,NTRK1,NUP85,OPHN1,OR10A4,OR1D2,OTX2,PDE4B,PDE4D,PDGFA,PDGFB,PDGFRB,PDLIM7,PF4,PF4V1,PIK3C2G,PIK3CA,PIK3CD,PIK3CG,PIK3R1,PIP5K1A,PIP5K1C,PLA2G10,PLA2G1B,PLA2G6,PLAU,PLCG1,PLD1,PLEKHG5,PLGRKT,PLP2,PLXNA1,PLXNA2,PLXNA3,PLXNA4,POU4F3,PPBP,PREX1,PRKCA,PRKCD,PRKCQ,PROK2,PSPN,PTAFR,PTCH1,PTGDR2,PTK2,PTPN11,PTPRA,PTPRJ,PTPRM,PTPRO,RAB13,RAC1,RAC2,RALA,RALBP1,RANBP9,RAP1GAP,RARRES2,RELN,RET,RHOG,RIPOR2,ROBO1,ROBO2,ROBO3,RPL24,RPS6KA5,RYK,S100A12,S100A8,S100A9,S1PR1,SAA1,SAA2,SAA2-SAA4,SAA4,SBDS,SCG2,SCN1B,SCRIB,SEMA3A,SEMA3C,SEMA3D,SEMA3E,SEMA3G,SEMA4A,SEMA4B,SEMA4C,SEMA4D,SEMA4G,SEMA5A,SEMA6A,SEMA6C,SEMA7A,SERPIND1,SH3KBP1,SHC1,SHC3,SIAH1,SIAH2,SLIT1,SLIT2,SLIT3,SMAD4,SOS1,SPN,SPON2,SPTB,SPTBN2,SPTBN5,SRC,STYK1,SYK,TGFB2,TNFRSF11A,TNFRSF8,TNFSF11,TNR,TREM1,TRPM2,TRPM4,TSC2,TUBB3,TYMP,UNC5A,UNC5B,UNC5C,UNC5D,VANGL2,VASP,VAV1,VAV3,VCAM1,VEGFA,VEGFC,VEGFD,VLDLR,WNT3,WNT3A,WNT5A,XCL1,XCL2,XCR1,ZNF580	TetrapodAncestor	160.378
GO.Biological.Process	GO:0008283	cell.proliferation	153	4.347023e-165	5.615050e-161	3.669967e-163	1.171662e+0	ABL1,ACE,ACHE,ACVR2A,ACVRL1,ADRA1B,ADRA1D,AGT,ALK,ALKBH3,APOA1,APPL1,APPL2,AR,AREG,ARHGEF1,ARHGEF2,ARID2,ARTN,ARX,ASCC3,ASCL1,ASPM,ATF5,ATOH8,AURKB,AXIN2,AZI2,BABAM1,BAD,BAK1,BAX,BCAR1,BCAT1,BCL2,BCL2L1,BCL2L2,BCL2L2-PABPN1,BHLHE41,BIN1,BLZF1,BMP10,BMP2,BMP4,BMP7,BMPER,BMPR2,BOP1,BRAT1,BST2,BTBD10,BTRC,BUB1,BYSL,C3orf58,C6orf89,CARD11,CCKBR,CCND1,CCND3,CD151,CD160,CD180,CD276,CD34,CD40,CD5,CD70,CD74,CD81,CD86,CDC14A,CDC16,CDC25A,CDC25C,CDC27,CDH13,CDK1,CDK19,CDK5,CDK5R1,CDK7,CDK9,CDV3,CEBPB,CEMP1,CENPF,CEP120,CER1,CHRM1,CHRM3,CHRM4,CHRM5,CITED1,CITED2,CKLF,CKS2,CLK1,CLU,CMC4,CNOT11,COL4A3,COL8A1,COL8A2,COPS2,CR2,CREG1,CRIP1,CSE1L,CSF1,CSF1R,CSGALNACT1,CSPG4,CTF1,CTGF,CTNNB1,CTPS1,CUL1,CUL5,CUZD1,CXCL1,CYP1A1,CYR61,DAB2,DACH1,DAGLA,DAGLB,DBN1,DCHS1,DCHS2,DCT,DDIT4,DDR2,DDX41,DISC1,DIXDC1,DKC1,DLG1,DLGAP5,DLX5,DMRT1,DOCK2,DOCK8,DUSP22,E2F8,E4F1,EBI3,ECD,EEF2,EGFR,EGR1,EHF,EIF2S2,ELF4,ELF5,ELN,EML1,EMP1,EMX2,ENPEP,ENSG00000243696,ENTPD5,EPHA2,EPHB1,EPO,EPS15,EPS8,ERBB2,ERBB4,ERCC1,ERCC2,EREG,ERG,ERN1,ESR1,ETV6,F2RL1,FABP7,FAM83B,FAM83D,FAT4,FBXL7,FBXO4,FBXW8,FER,FERMT1,FES,FGF1,FGF10,FGF13,FGF2,FGF4,FGF6,FGF7,FGFR1,FGFR2,FGFR3,FIGNL1,FKBP1A,FKBP1B,FOXC1,FOXC2,FOXN1,FRAT2,FRS2,FSCN1,FSHB,FURIN,FZD3,FZD6,FZD9,GAB1,GAPT,GAS6,GBX2,GINS1,GINS4,GLI2,GLI3,GLUL,GMNC,GNG2,GNL3,GOLPH3,GPC3,GPC4,GRHL2,GRPR,GSTP1,H3F3A,HAND2,HDGF,HDGFL3,HELLS,HGF,HHEX,HLCS,HMGA2,HMGB1,HMOX1,HNF1B,HOOK3,HPRT1,HRAS,HTR1A,ID2,ID4,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNAR2,IFNB1,IFNE,IFNK,IFNW1,IFT20,IGF1,IGF2BP1,IGFBP4,IGFBP5,IGSF8,IHH,IL10,IL12A,IL12B,IL15,IL15RA,IL18,IL18RAP,IL1A,IL23A,IL33,IL5RA,IL6,IL7R,IMPDH1,INSL4,IRF2,IRF6,IRS2,ISG20,ITGA2,ITPKB,JUNB,KALRN,KCNA1,KHDRBS1,KIF15,KIF1A,KIF2C,KITLG,KLF10,KRT16,KRT2,LAMA5,LARP1,LEF1,LGI4,LGR4,LGR5,LHX5,LIG4,LIPA,LIPG,LMNTD1,LOXL2,LRP1,LRP6,LTK,LY86,MALT1,MAP3K11,MAP4K1,MAPK1,MAPRE1,MAPRE2,MAS1,MATK,MCM10,MCM7,MDM4,MECOM,MEF2C,MEGF10,MELK,MET,MIA,MIF,MMP14,MMP16,MORF4L1,MPL,MRE11,MRM2,MRPS27,MS4A1,MSN,MSX1,MTCP1,MTSS1,MUSTN1,MXD1,NAA35,NAA60,NAB2,NANOG,NASP,NBN,NCAPG2,NCSTN,NDEL1,NDP,NDRG4,NES,NEUROD4,NF2,NKX2-5,NKX3-1,NKX6-1,NOTCH1,NOV,NOX5,NPPC,NPR3,NPY,NR4A3,NRDC,NUDC,NUMB,NUMBL,OCA2,ORC3,OSM,OSR1,P2RX7,PAFAH1B1,PAK1IP1,PAK4,PAK5,PALB2,PCM1,PCNA,PDAP1,PDGFRB,PDPN,PDXK,PELO,PEMT,PENK,PES1,PICALM,PIK3CG,PIM1,PIM2,PITX2,PLCE1,PLCL2,PLK1,PLXNB2,POC1B,POU3F2,POU3F3,PPARD,PPP1R8,PPP3CB,PRDM1,PRDM4,PRDX1,PRG4,PRKAR1A,PRKCD,PRKD1,PRKDC,PRKX,PRL,PRMT5,PROK2,PROX1,PRPF19,PSEN1,PSMG1,PTCH1,PTEN,PTK2B,PURB,PYY,RAC1,RACGAP1,RAF1,RAG2,RAP1B,RAPGEF3,RASGRF1,RASGRP4,RBBP7,RC3H1,RC3H2,REG3A,RERE,RETNLB,RHBDF1,RIPK2,RNF43,ROS1,RPGRIP1,RPL23A,RPS27,RPS6,RPS6KA1,RRN3,RUNX1,RXRA,RYK,S100B,SATB1,SBDS,SCARB1,SCRIB,SDCBP2,SDR16C5,SEMA5A,SETMAR,SFRP2,SH2D2A,SHB,SIDT2,SIPA1,SIX2,SKI,SKP2,SLAMF6,SLC11A1,SMAD4,SOX11,SOX4,SOX5,SOX9,SPHK2,SRA1,SRC,SRRT,STAT1,STAT6,STC1,STIL,SYK,TACC1,TACC2,TACC3,TACSTD2,TAF8,TBCK,TBK1,TBX1,TBX20,TEAD3,TEK,TENM4,TGFB1,TGFB2,TGFBI,THAP1,THPO,TLR4,TMEM110-MUSTN1,TNF,TNFRSF17,TNFRSF4,TNFSF11,TNFSF13B,TNFSF14,TNFSF18,TNFSF8,TNFSF9,TP53,TP63,TPX2,TRAIP,TRIM71,TRNP1,TSPO,TWIST1,TXLNA,TXN,TXNRD1,TYR,UBE2L3,UBE2V2,UBR5,UCHL1,UHRF1,UHRF2,USP13,USP28,USP8,USPL1,VEGFD,VTI1B,WDR12,WNT1,WNT10B,WNT16,WNT3,WNT3A,WNT4,WNT5A,WNT7A,WNT7B,XBP1,XRCC5,YAP1,YME1L1,YY1AP1,ZEB1,ZFP36L1,ZFP36L2,ZNRF3,ZPR1	TetrapodAncestor	160.251
GO.Biological.Process	GO:0001503	ossification	154	1.863004e-164	2.406442e-160	1.562625e-162	1.286295e+0	ACHE,ADAR,AHSG,ALOX15,ALPL,ALYREF,AMELX,ANO6,ASF1A,ASPN,ATP6V0A4,ATP6V1B1,AXIN2,BCAP29,BCL2,BGLAP,BMP1,BMP2,BMP4,BMP5,BMP6,BMP7,BMP8A,BMP8B,CASR,CAT,CBFB,CCDC47,CCL3,CDH11,CER1,CHRD,CHRDL1,CHRDL2,CLEC11A,CLEC3B,CLTC,COL10A1,COL11A1,COL13A1,COL1A1,COL2A1,COL5A2,COL6A1,CREB3L1,CSGALNACT1,CTGF,CYP24A1,CYP27B1,CYR61,DCHS1,DDR2,DDX21,DHX9,DLX5,DMP1,DNAJC13,DSPP,DUOX2,EGFR,EIF2AK3,EPHA2,ERCC2,EXT1,EXT2,FASN,FAT4,FBL,FBXL15,FGF18,FGF9,FGFR2,FGFR3,FHL2,FIGNL1,FOXC1,FOXC2,FSTL3,FZD1,FZD9,GDF10,GDF2,GDF5,GLI2,GNAS,GPC3,GPLD1,GPM6B,GPNMB,H3F3A,HDAC4,HIRA,HNRNPC,HNRNPU,HSD17B4,IARS,IBSP,IFITM1,IFITM5,IGF1,IGF2,IGFBP5,IGSF10,IHH,IMPAD1,ITGA11,JUNB,KAZALD1,KLF10,LEF1,LEP,LGR4,LIMD1,LRP5,MEF2C,MEF2D,MEN1,MGP,MINPP1,MMP13,MMP14,MMP16,MMP9,MN1,MRC2,MSX2,MYBBP1A,MYOG,NAB2,NF1,NOG,NPPC,NPR2,OSTF1,PDLIM7,PENK,PEX7,PHB,PHEX,PHOSPHO1,PKDCC,PLXNB1,PPARGC1B,PSMC2,PTH1R,PTHLH,PTN,RASSF2,RDH14,RIPPLY2,ROR2,RPL38,RPS11,RPS15,RRAS2,RRBP1,RSL1D1,RSPO2,RUNX1,RUNX2,RYR1,SATB2,SBDS,SCX,SEMA4D,SEMA7A,SFRP1,SHOX2,SLC26A2,SLC34A1,SMAD5,SMO,SNAI1,SNAI2,SND1,SNRNP200,SOST,SOX2,SOX8,SOX9,SP7,SPP1,STC1,SUCO,SUN1,SYNCRIP,TAPT1,TEK,TGFB1,THBS3,THRA,TMEM64,TNC,TNFRSF11A,TNFSF11,TNN,TP53INP2,TPM4,TRAF6,TUFT1,TWIST1,UFL1,VCAN,WNT11,WNT3,WNT3A,WWOX,WWTR1,ZBTB40	TetrapodAncestor	159.619
GO.Biological.Process	GO:0061448	connective.tissue.development	155	7.132789e-164	9.213424e-160	5.944144e-162	1.293300e+0	AACS,ACAT1,ACTA2,ALX1,AMELX,AMER1,ARID5B,ARRDC3,AXIN2,BARX2,BBS4,BMP1,BMP2,BMP4,BMP5,BMP6,BMP7,BMP8A,BMP8B,BMPR1A,BMPR1B,BMPR2,CASR,CD34,CD44,CDK4,CER1,CHI3L1,CHRDL2,CHST11,CNMD,COL10A1,COL11A1,COL1A1,COL27A1,COL2A1,COL5A1,CREB3L2,CRIP1,CSF1,CSGALNACT1,CTGF,CYR61,CYTL1,DGAT2,DYRK1B,EBF2,EDN1,EGR1,EIF2AK3,ENSG00000243696,ESRRA,EVC,FGF18,FGF2,FGF4,FGF6,FGF9,FGFR1,FGFR3,FOXA1,FOXC2,GDF2,GDF5,GLI2,GNAS,GPLD1,GPR4,HAND1,HAND2,HES5,HIF1A,HMGA2,ID4,IHH,IL17F,IMPAD1,ITGB8,LEP,LRP5,LRP6,LUM,MAPK14,MAPK3,MATN1,MEF2C,MEF2D,MEX3C,MGP,MKKS,MMP13,MSX1,MSX2,MUSTN1,MYCN,NFIB,NOG,NOTCH1,NOV,NPPC,OSR1,OTOR,OXCT1,PAX7,PAXIP1,PDGFB,PDGFRB,PIK3CA,PITX1,PKD1,POC1A,PPARD,PPARGC1A,PRRX1,PTH1R,RARA,RARB,RARG,ROR2,RORC,RSPO2,RUNX1,RUNX2,SATB2,SCX,SELENOM,SERPINH1,SFRP2,SHOX2,SIX2,SLC25A25,SLC39A13,SMAD5,SNAI1,SNAI2,SNX19,SOX8,SOX9,SRF,STC1,SULF2,TAPT1,TBL1XR1,TGFB1,TGFBI,TGFBR2,THBS3,THRA,TIMP1,TMEM110-MUSTN1,TNMD,TRIP11,TYMS,UMODL1,WNT10B,WNT5A,WNT7A,WNT7B,XBP1,ZBTB16,ZEB1	TetrapodAncestor	159.036
GO.Biological.Process	GO:0060627	regulation.of.vesicle-mediated.transport	156	2.375145e-163	3.067975e-159	1.966651e-161	1.233289e+0	AAK1,ABL1,ABL2,ABR,ACSL3,ACTN4,ADGRE2,ADIPOQ,ADORA2B,ADRA2A,AHI1,AHSG,AKT2,ALOX15,ANGPT1,ANKRD27,ANO6,ANXA1,AP1G1,AP2S1,APELA,APLN,APOA5,APOC1,APOC3,APOE,ARF1,ARF6,ARHGAP1,ARRB1,ARRB2,ATAD1,ATG3,ATG5,ATP13A2,ATP6AP1,ATXN2,AXL,BCR,BET1L,BICD1,BIN1,BRAF,BTBD9,C12orf4,C2CD5,C3,C4A,C4B,C4BPA,C4BPB,CACNA1G,CACNA1H,CACNA1I,CADPS2,CALR,CALY,CAMK1D,CAV1,CAV3,CBL,CBLL1,CCL19,CCL2,CCL21,CCR2,CD14,CD2AP,CD300A,CD300LF,CD36,CD47,CD63,CDH13,CDK5,CDK5R2,CFTR,CHMP2A,CHMP3,CLASP1,CLASP2,CLIP3,CNST,CORO1A,CPLX1,CPLX2,CSK,CYBA,CYFIP1,DAB2,DKK1,DLG4,DLL1,DNAJC13,DNM1,DNM1L,DNM2,DOC2A,DOC2B,DOCK2,DRD2,EEF2K,EGF,EHD1,EHD2,EHD4,EPHA3,EVI5L,EXPH5,EZR,F2RL1,FCER1G,FER,FES,FGF14,FGG,FGR,FLOT1,FMR1,FOXF1,GAB2,GAS1,GAS6,GATA2,GOPC,GOSR1,GPC3,GREM1,GRIK5,HAP1,HCK,HGS,HIP1,HIP1R,HIST1H1A,HMGB1,HMOX1,HNRNPK,IFNG,IL13,IL13RA2,IL1B,IL1RAPL1,IL4,ITGA2,ITGAM,ITGAV,ITGB2,KCNB1,KIF5B,LDLR,LDLRAP1,LGALS3,LGALS9,LGI3,LLGL2,LMAN2,LRP1,LRPAP1,LRRK2,LRRTM1,LRRTM2,LRSAM1,LYN,LYPLA1,MAGI2,MAP2K2,MAPK1,MAPK3,MBL2,MCTP1,MERTK,MFGE8,MIB1,MICAL1,MSN,MTMR2,MVB12A,MYO18A,NAPA,NCKAP1L,NCS1,NDRG4,NECAB2,NEDD4L,NLGN1,NOTCH1,NR1H2,NR1H3,NRP1,NSF,NTF3,OPHN1,PACSIN2,PACSIN3,PCLO,PDCD6IP,PDPK1,PFN2,PICALM,PICK1,PINK1,PKDCC,PLA2G6,PLAA,PLCG2,PPARG,PPP3CA,PPT1,PRAM1,PREB,PRKAA1,PRKCG,PRKD1,PRKN,PROM2,PTAFR,PTEN,PTPN1,PTPN23,PTX3,PYCARD,RAB11B,RAB14,RAB15,RAB17,RAB21,RAB25,RAB26,RAB27A,RAB27B,RAB29,RAB2B,RAB33B,RAB37,RAB3B,RAB3C,RAB3D,RAB3GAP1,RAB4A,RAB4B,RAB5A,RAB5B,RAB7A,RAB8A,RAB8B,RABGAP1,RABGAP1L,RAC1,RAC2,RALA,RALB,RAP1A,RAP1B,RAPGEF1,RDX,REST,RIMS1,RIMS3,RIMS4,RINT1,RIT2,RNF139,RPH3A,RPH3AL,RSG1,RSPO1,RUBCN,RUFY1,RUFY2,RUNDC1,SCAMP5,SCARB1,SCFD1,SCYL2,SDC4,SDCBP,SEC24B,SELE,SEPT5,SFRP4,SGIP1,SGSM1,SGSM2,SGSM3,SH3GL2,SLC11A1,SLC30A8,SMAP1,SMPD3,SNAP91,SNCA,SNF8,SNX12,SNX17,SNX4,SORL1,SPACA3,SRC,STAM,STAP1,STON2,STX18,STX1A,STX1B,STX4,STXBP1,STXBP2,STXBP5,STXBP5L,STXBP6,STYK1,SYK,SYN1,SYT1,SYT10,SYT11,SYT13,SYT15,SYT17,SYT2,SYT4,SYT5,SYT6,SYT7,SYT8,SYT9,SYTL1,SYTL3,SYTL4,SYTL5,TBC1D1,TBC1D10A,TBC1D10C,TBC1D14,TBC1D15,TBC1D16,TBC1D17,TBC1D20,TBC1D21,TBC1D22A,TBC1D22B,TBC1D26,TBC1D28,TBC1D2B,TBC1D3,TBC1D30,TBC1D3B,TBC1D3F,TBC1D3K,TBC1D4,TBC1D5,TBC1D8,TBC1D8B,TBC1D9,TBC1D9B,TBCK,TF,TFR2,TGFB1,TLR2,TMEM27,TNF,TNK2,TOR1A,TRIM9,TRPV6,TSC2,TSG101,TUB,TULP1,UNC119,UNC13B,USP6NL,UVRAG,VAMP2,VAMP8,VEGFA,VPS11,VPS16,VPS18,VPS28,VPS37B,VPS41,VPS4A,VPS4B,VSNL1,VTN,WNT3A,WNT5A,YIPF5,ZFYVE16,ZP3	TetrapodAncestor	158.513
GO.Biological.Process	GO:0010564	regulation.of.cell.cycle.process	157	2.093214e-162	2.703805e-158	1.722168e-160	1.196797e+0	ACTR1A,AIF1,AKT2,ALMS1,ANAPC1,ANAPC11,ANAPC16,ANAPC2,ANAPC4,ANAPC5,ANKRD17,ANKRD53,ANLN,ANXA1,APAF1,APC,APEX1,APP,ATAD5,ATF5,ATM,ATP2B4,AURKA,AURKAIP1,AURKB,AURKC,AXIN2,BAX,BBS4,BCL2,BCL6,BECN1,BID,BIN1,BIRC6,BMI1,BMP4,BMP7,BRCA1,BRD4,BTC,BTG2,BTRC,BUB1,C10orf99,C8orf4,CALR,CARM1,CASP2,CAV2,CBX3,CCDC8,CCL2,CCNB1,CCNB3,CCND1,CCND2,CCNF,CCNK,CCP110,CD28,CDC14A,CDC14B,CDC16,CDC20,CDC23,CDC25A,CDC25B,CDC25C,CDC26,CDC27,CDC42,CDC45,CDC6,CDC73,CDCA5,CDK1,CDK10,CDK13,CDK2,CDK2AP2,CDK4,CDK5,CDK5R1,CDK5RAP2,CDK6,CDK9,CDKN1A,CDKN1B,CDKN1C,CDKN2B,CDKN2D,CENPE,CENPF,CENPJ,CEP120,CEP164,CEP192,CEP250,CEP41,CEP57,CEP63,CEP72,CEP78,CEP85,CEP97,CHEK1,CHEK2,CHMP1A,CHMP1B,CHMP2A,CHMP2B,CHMP3,CHMP4B,CHMP4C,CHMP5,CHORDC1,CIT,CKAP5,CLASP1,CLTC,CNOT1,CNOT10,CNOT11,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT8,CNTRL,CRADD,CRLF3,CSNK1D,CSNK1E,CTCF,CTDSP1,CTDSP2,CTDSPL,CTGF,CTNNB1,CUL1,CUL3,CUL4A,CUL7,CUL9,CXCR5,CYP1A1,DAB2IP,DACH1,DACT1,DAPK3,DAZL,DBF4B,DCTN1,DCTN3,DCUN1D3,DDB1,DDRGK1,DDX11,DDX3X,DLGAP5,DMRT1,DONSON,DRD2,DRD3,DUSP1,DYNC1H1,DYNC1LI1,DYNLL1,E2F1,E2F4,E2F6,E2F7,E2F8,E4F1,ECD,ECT2,EDN1,EDN3,EED,EGF,EGFR,EP300,EPC1,EPGN,ERCC2,ERCC3,EREG,ESPL1,EZH2,FAM83D,FANCI,FBXL7,FBXO31,FBXO5,FBXO7,FBXW5,FBXW7,FEN1,FGF10,FGFR1,FGFR1OP,FLCN,FOXE3,FOXM1,FOXN3,FOXO4,FZD9,FZR1,GADD45A,GATA6,GEN1,GIGYF2,GIPC1,GJC2,GML,GNAI1,GPER1,GPNMB,GPR132,GPR3,GTSE1,H2AFY,HAUS2,HAUS3,HAUS4,HAUS6,HAUS7,HAUS8,HDAC8,HECW2,HMGA2,HMGN5,HMMR,HNRNPU,HSP90AB1,HSPA2,HUS1,HUS1B,ID2,IGF1,IGF2,IK,IL1A,IL1B,INO80,INS,INSM1,JADE1,KANK2,KCNA5,KCNH5,KIF11,KIF20B,KIF25,KIF3B,KLHL21,KLHL22,KNSTRN,L3MBTL1,L3MBTL2,LCMT1,LIF,LRP5,LSM11,MAD1L1,MAD2L1,MAD2L1BP,MAD2L2,MAP10,MAP9,MAPRE1,MAX,MCPH1,MDM1,MDM2,MDM4,MECP2,MED25,MEN1,MEPCE,MGA,MIF,MIIP,MLXIPL,MOS,MRE11,MRNIP,MSH2,MSX1,MSX2,MTA3,MTBP,MUC1,MUS81,MYBBP1A,MYO16,MYO19,MYOG,NAA10,NAE1,NANOS2,NBN,NDC80,NEDD1,NEK10,NEK11,NEK6,NEUROD1,NEUROG1,NINL,NOP53,NPM1,NPM2,NSMCE2,NUBP1,NUDT16,NUP62,NUPR2,NUSAP1,ODF2,OPN1LW,OR1A2,OR2A4,ORAOV1,OSM,OVOL1,PAF1,PAFAH1B1,PAGR1,PARP3,PAXIP1,PBX1,PCBP4,PCGF2,PCID2,PCM1,PCNA,PCNT,PDCD6IP,PDE3A,PDGFB,PDGFRB,PDPN,PDXP,PHC1,PHC3,PHIP,PHOX2B,PID1,PIDD1,PIK3C3,PIN1,PINX1,PIWIL2,PKD1,PKD2,PKHD1,PKIA,PKMYT1,PLAGL1,PLCB1,PLK1,PLK2,PLK3,PLK4,PLK5,PML,POC1A,POU4F1,PPP1R9B,PPP2R5B,PRDM9,PRKACA,PRKAR1A,PRKAR2B,PRKCE,PRKDC,PRMT1,PRMT5,PRPF40A,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTEN,PTTG1,PTTG2,RAB11FIP4,RACGAP1,RAD1,RAD17,RAD21,RAD51,RAD51B,RAD51C,RAE1,RANBP2,RANBP3,RANBP3L,RB1,RBBP4,RBBP7,RBBP8,RBM14,RCC1,RCC2,RDX,RFWD3,RGCC,RGPD4,RHNO1,RING1,RINT1,RMI2,RNASEH2B,RNF2,RNF4,ROCK2,RPA2,RPL23,RPRD1B,RPS27A,RPS27L,RPTOR,RRM2,RXFP3,RYBP,SETD2,SETMAR,SFI1,SFN,SFPQ,SFRP1,SH2B1,SH3GLB1,SIRT2,SLC25A33,SLF1,SLF2,SLFN11,SMARCA4,SMC1A,SMC5,SOX15,SOX4,SOX9,SPAST,SSNA1,SSTR5,STAG1,STAG2,STIL,STXBP4,SUSD2,SVIL,TACC3,TAF1,TAS1R2,TAS2R13,TERF1,TERF2,TERT,TEX14,TFDP2,TGFB1,TICRR,TMEM67,TMOD3,TNKS,TNKS1BP1,TOM1L1,TOPAZ1,TOPBP1,TP53,TP63,TP73,TPR,TPRA1,TPX2,TRIAP1,TRIM37,TRIP13,TTK,TTL,TUBA1A,TUBB,TUBB4A,TUBB4B,TXLNG,UBC,UBE2C,UBE2D1,UBE2E1,UBE2E2,UHRF2,USP47,UVRAG,UXT,VPS4A,VPS4B,WAPL,WEE2,WIZ,WNT10B,WNT4,WNT5A,XPC,YAF2,YTHDF2,YWHAE,YWHAG,ZBTB17,ZFP36L1,ZFP36L2,ZFYVE19,ZNF16,ZNF207,ZNF385A,ZNF830,ZW10	TetrapodAncestor	157.568
GO.Biological.Process	GO:0051098	regulation.of.binding	158	4.132877e-162	5.338437e-158	3.378758e-160	1.254444e+0	ABL1,ACD,ACE,ADAM15,ADD1,ADIPOQ,ADNP,ADRB2,AES,AGER,AIDA,AMFR,ANGPT1,ANKRD33,APP,ARHGAP28,ARHGEF7,ARRB1,ARRB2,AURKA,AURKB,BAK1,BAMBI,BAX,BCL2,BCL3,BDNF,BMP2,BMP4,CALM2,CALM3,CAMK1,CAPRIN2,CARD16,CARD18,CARM1,CAV1,CCL23,CCM2L,CD36,CDC42,CDCA5,CDK5,CDK9,CDON,CEBPG,CFHR1,CFHR2,CFHR5,CRBN,CRK,CRMP1,CRTAC1,CSF3,CSNK1A1,CSNK1E,CSNK2B,CTNNB1,CTSZ,CYP2D6,DAB2,DAB2IP,DACT1,DDRGK1,DDX11,DERL1,DHX9,DISC1,DKK1,DOT1L,DPH3,DTNBP1,DTX3L,DVL1,E2F1,EBF2,EDF1,EGF,EIF3C,EIF3D,EIF3E,EIF4A3,EP300,EPB41,EPB41L5,EPHA4,ERCC2,ERCC4,FAM220A,FBXO18,FKBP1A,FLOT1,FMR1,FOXC1,FRMD7,GAS8,GATA3,GMNN,GNL3L,GOLGA2,GREM2,GTSE1,GZMA,HABP4,HAND1,HAND2,HDAC2,HDAC4,HDAC5,HDAC8,HERPUD1,HES1,HEY1,HEY2,HIP1R,HIPK2,HJURP,HMBOX1,HMGA2,HMGB1,HMGB2,HMOX1,HSF1,HSP90AB1,HSPA5,ID1,IFIT1,IFIT2,IFNG,IGF1,IL10,IRF4,ISL1,ITGA2,ITGA4,JAK2,JUN,KDM1A,KDM4D,KLF4,KRIT1,LARP6,LDLRAP1,LDOC1,LEF1,LFNG,LHX2,LIF,LRP1,LRPAP1,LRRK2,MAD2L2,MAPK3,MAPK8,MAPRE1,MAPRE3,MBD2,MDFI,MED25,MEF2C,MEN1,MEPCE,MET,MFNG,MITD1,MMP9,MSX1,MSX2,MYOCD,NCBP1,NES,NEUROD1,NFATC4,NKX3-1,NMD3,NME1,NOG,NRG1,NRP1,NSD1,NUCKS1,P2RY1,PARK7,PARP1,PARP9,PAX7,PCBD1,PDGFB,PER2,PEX14,PEX19,PHLDA2,PIM2,PIN1,PINX1,PITX2,PKD1,PLCL1,PLCL2,PLK1,PLK2,PLN,PLXND1,POU4F1,PPARA,PPARG,PPP1CA,PPP3CA,PRKACA,PRKCD,PRKN,PRMT7,PRMT8,PSEN1,PYGO2,RALB,RAPGEF2,RARA,RB1,RFNG,RIPK2,RIPOR2,RPL11,RSF1,RUVBL2,S100A10,SIRT2,SKI,SLN,SLPI,SMAD2,SMAD4,SMO,SNAPIN,SORL1,SOX11,SP100,SPAG8,SPAG9,SPPL3,SRC,SRI,STK4,STMN1,STPG1,STUB1,SUMO1,SUMO3,TAF1,TDG,TERT,TEX14,TFIP11,TGFB1,TGFBR1,TIAM1,TICAM1,TIRAP,TMBIM6,TMC8,TMEM173,TNFSF18,TNKS,TRAF2,TRAF4,TRAF6,TRIB3,TRIM28,TRIM6,TUNAR,TWIST1,TXN,UBASH3B,VTN,WAPL,WFIKKN1,WNT3A,WNT5A,XIRP1,ZBTB7C,ZFP90,ZFPM1,ZNF462,ZNF593,ZNF675	TetrapodAncestor	157.273
GO.Biological.Process	GO:0070373	negative.regulation.of.ERK1.and.ERK2.cascade	159	5.039332e-161	6.509305e-157	4.093903e-159	1.598541e+0	ABL1,ADIPOQ,ARRB1,ATF3,C1QL4,C3orf33,CAMK2N1,CNKSR3,CRYBA1,CSK,DAB2IP,DLG1,DUSP1,DUSP10,DUSP26,DUSP3,DUSP6,EIF3A,EPHB2,ERRFI1,EZR,FBLN1,FLCN,GPER1,GSTP1,KLF4,LIF,LMO3,LYN,NLRP6,PHB,PIN1,PSCA,PTEN,PTPN1,PTPRR,RANBP9,RAPGEF1,RGS14,RPS6KA6,SIRT3,SLC9A3R1,SMAD4,SPRY1,SPRY2,SPRY4,SYNJ2BP,TBC1D10C,TIMP3,TLR4,TNIP1,VRK3,WNK2	TetrapodAncestor	156.186
GO.Biological.Process	GO:0003007	heart.morphogenesis	160	8.852267e-161	1.143447e-156	7.146546e-159	1.262715e+0	ACVRL1,ADAM15,ADAMTS1,ADGRG6,AHI1,ANKRD1,ARID2,ARL13B,ASXL1,AXIN2,BBS4,BBS7,BMP10,BMP2,BMP4,BMP5,BMP7,BMPR1A,BMPR2,C2CD3,CAV3,CCDC103,CCDC40,CCM2L,CHD7,CITED2,CLDN5,COL11A1,COL2A1,COL5A1,CYR61,DCHS1,DHRS3,DLC1,DLL1,DLL4,DNAAF1,DSP,EFNA1,EGLN1,ENG,EPHB4,ERG,EYA1,FAT4,FGFR2,FGFRL1,FHL2,FKBP1A,FLRT2,FOXC1,FOXC2,FOXF1,FOXH1,FOXN4,FZD1,FZD2,GAA,GATA3,GATA4,GATA6,GRHL2,GSK3A,HAND1,HAND2,HAS2,HEG1,HES1,HEY1,HEY2,HEYL,HIF1A,HTR2B,IFT172,IFT52,IFT57,IHH,ISL1,JAG1,JUN,KDM6A,LBX1,LEFTY1,LEMD2,MDM2,MEF2C,MEGF8,MESP1,MESP2,MIB1,MKKS,MSX1,MSX2,MTOR,MYBPC3,MYH6,MYH7,MYL3,MYLK2,NDRG4,NIPBL,NKX2-5,NOG,NOTCH1,NOTCH2,NOTO,NPHP3,NPY1R,NPY2R,NPY5R,NRG1,NRP1,NRP2,NSD2,OLFM1,OVOL2,PITX2,PKD2,PKP2,PLXND1,POU4F1,PPP1R13L,PROX1,PSEN1,PTCD2,PTCH1,PTK2,RARA,RARB,RBP4,RBPJ,RTN4,RXRA,RYR1,RYR2,S1PR1,SEC24B,SEMA3C,SETDB2,SFRP2,SHOX2,SIRT6,SMAD4,SMAD7,SMO,SNAI1,SNAI2,SOS1,SOX11,SOX17,SOX18,SOX4,SOX9,SPRY1,SRF,STIL,SUFU,T,TAB1,TBX1,TBX2,TBX20,TBX3,TBX5,TEAD2,TEK,TGFB1,TGFB2,TGFBR1,TGFBR2,TH,TMED2,TMEM100,TNNC1,TNNI3,TNNT2,TTN,TWIST1,VANGL2,VEGFA,WNT11,WNT16,WNT3A,WNT5A,ZFPM1,ZFPM2,ZIC3,ZMIZ1	TetrapodAncestor	155.942
GO.Biological.Process	GO:0070302	regulation.of.stress-activated.protein.kinase.signaling.cascade	161	4.955777e-159	6.401377e-155	3.976011e-157	1.301853e+0	AGER,AIDA,AMBP,ANKRD6,APP,ARL6IP5,BMP2,CAV3,CCL19,CCL21,CCR7,CD27,CDC42,CTGF,DAB2IP,DACT1,DAXX,DBNL,DKK1,DLG1,DNAJA1,DTNBP1,DUSP10,DUSP15,DUSP19,DUSP22,DUSP3,DVL3,EDA2R,EDAR,EDN1,EGFR,EIF2AK2,EPHA4,EPHB1,ERCC6,ERN1,ERN2,EZR,F2RL1,FAS,FGD2,FGF19,FKTN,FLT4,FOXM1,FOXO1,FZD10,FZD4,FZD5,FZD7,FZD8,GADD45A,GADD45B,GADD45G,GDF6,GRIK2,GSTP1,HACD3,HAND2,HDAC3,HGF,HIPK2,HMGB1,HMGCR,HRAS,HSPH1,IGBP1,IGF1R,IL1B,IL26,INAVA,ITCH,KARS,LEP,LTBR,LYN,MAGI3,MAP2K2,MAP2K4,MAP2K7,MAP3K10,MAP3K11,MAP3K2,MAP3K21,MAP3K3,MAP3K4,MAP3K5,MAP3K6,MAP3K7,MAP3K9,MAP4K1,MAP4K4,MAPK1,MAPK3,MAPK8IP1,MAPK8IP3,MARVELD3,MECOM,MEN1,MID1,MINK1,MUL1,MYC,NBR1,NCF1,NOD1,NRK,OPRK1,PAFAH1B1,PAK1,PBK,PDCD10,PER1,PHLPP1,PINK1,PKN1,PLCB1,PPEF2,PRDX1,PRKN,PRMT1,PTK2B,PTPN1,PTPN22,PYCARD,RAP2A,RAPGEF1,RASGRP1,RASSF2,RB1CC1,RIPK1,RIPK2,ROR2,RPS3,SASH1,SDCBP,SEMA4C,SERPINB3,SFRP1,SFRP2,SH3RF1,SPAG9,SYK,TAOK1,TAOK2,TGFB2,TIAM1,TIRAP,TLR3,TLR4,TLR6,TLR9,TNF,TNFRSF11A,TNFRSF19,TNFSF11,TNIK,TP73,TPD52L1,TRAF2,TRAF4,TRAF6,ULK4,UNC5CL,VANGL2,VEGFA,WNT16,WNT5A,WNT7A,WNT7B,XDH,ZC3H12A,ZNF622,ZNF675	TetrapodAncestor	154.194
GO.Biological.Process	GO:0009792	embryo.development.ending.in.birth.or.egg.hatching	162	1.724841e-157	2.227977e-153	1.375295e-155	1.179982e+0	ABI1,ABL1,ACSL4,ACVR1B,ACVR2A,ACVRL1,ADA,ADAR,ADD1,ALKBH1,ALS2,ALX1,ALX4,AMBRA1,AMOT,ANGPT1,APAF1,APBA1,APBA2,APBA3,APOB,AR,ARHGAP35,ARID1A,ARL13B,ARNT2,ASCL2,ATM,ATP6AP2,AXIN2,B9D1,BBS4,BCL10,BCL2L1,BCL2L11,BIRC6,BMP2,BMP4,BMP5,BMP7,BMPR1A,BMPR2,BRCA1,BYSL,C2CD3,C5,C6,CAMSAP3,CAPN2,CASP8,CCM2,CCNB1,CCNB1IP1,CDKN1C,CEBPA,CEBPB,CECR2,CELSR1,CENPU,CFL1,CHD7,CHD8,CHRD,CHST11,CITED1,CNOT2,CNOT3,COBL,COL11A1,COL1A1,COL2A1,COPS3,CRB2,CTNNB1,CUL3,CUL4A,CYR61,DACT1,DAD1,DCHS1,DEAF1,DKK1,DLC1,DLG1,DLL1,DLL3,DNAJB6,DSCAML1,DUSP3,DVL1,DVL3,E2F7,E2F8,EDN1,EGFR,EGLN1,EIF2S2,EIF4A3,EIF4E2,ELF3,EMX1,EN1,ENDOG,EOMES,EP300,EPAS1,EPB41L5,EPHA2,EPN1,ERCC2,ETNK2,EXT1,EYA1,FAM212A,FBXW8,FERD3L,FGF9,FGFR1,FGFR2,FLCN,FLVCR1,FOSL1,FOXA1,FOXC1,FOXC2,FOXF1,FUT8,FUZ,FXN,FZD1,FZD2,FZD3,FZD5,FZD6,GABPA,GATA2,GATA3,GATA6,GBX2,GCM2,GDF3,GGNBP2,GINS1,GINS4,GJB3,GJB5,GLI2,GLI3,GNA12,GNA13,GNAS,GRB2,GRHL2,GRHL3,GSC,HAND1,HAND2,HEG1,HES1,HES3,HES5,HES7,HEY1,HEY2,HHEX,HIF1A,HINFP,HNF1B,HOXA1,HS6ST1,HSD17B2,HSF1,IFITM5,IFT140,IFT172,IFT52,IFT57,IGF2,IHH,IL10,INPP5B,INPP5K,INTU,ISL1,ITGB1,ITPK1,JAG2,JUNB,KBTBD8,KDM2B,KDM4C,KDM6A,KEAP1,KIAA1217,KIF20B,KLF2,KLHL12,KRT19,LATS1,LEF1,LFNG,LHX1,LHX2,LIF,LIG4,LMO4,LRP6,LUZP1,MAFF,MAFG,MAN2A1,MAPK1,MBD3,MBNL1,MBTD1,MDFI,MED21,MEF2C,MEGF8,MEOX1,MEOX2,MESP1,MESP2,MFN2,MIB1,MKS1,MMP14,MMP16,MSGN1,MSH2,MSX1,MTHFD1,MTHFD1L,MYCN,MYF6,MYH6,MYH9,MYO1E,NASP,NBN,NCAPG2,NCOA1,NDEL1,NDST1,NF1,NIPBL,NKX2-5,NKX2-6,NKX3-1,NKX3-2,NLE1,NMT1,NOG,NOLC1,NOS3,NOTCH1,NSDHL,OCRL,OOEP,OSR1,OVOL2,PALB2,PAX2,PAX5,PAX7,PBX1,PCDH12,PCDH8,PCGF2,PCSK5,PDCD6,PDGFB,PEF1,PFN1,PHACTR4,PITX2,PKD1,PKD2,PLAC1,PLCD3,PLCG1,PLG,PLK4,PLXNA2,PLXNB2,POGLUT1,POLG2,PRDM1,PRICKLE1,PRKACA,PRKDC,PROX1,PRPF19,PRRX1,PSEN1,PSMC3,PSMC4,PTCH1,PTK7,PTPRR,PYGO2,RALA,RARA,RARG,RARRES2,RBBP8,RBM46,RBP4,RBPJ,RDH10,RIC8A,RIPPLY1,RIPPLY2,RIPPLY3,RNASEH2B,ROR2,RPL7L1,RRN3,RRP7A,RSPO3,RTF1,RUNX2,RXRA,SALL2,SATB2,SBDS,SCRIB,SCX,SDC4,SEC24B,SEC24D,SEMA3C,SEMA4C,SETD2,SF3B6,SFRP1,SFRP2,SHOX2,SHROOM3,SIX2,SKI,SKIL,SLC30A1,SLC34A2,SLC39A3,SMAD2,SMAD4,SMO,SNAI1,SOCS3,SOX10,SOX11,SOX17,SOX18,SOX4,SOX8,SOX9,SPIC,SPINT1,SRF,SRSF1,SSBP3,ST14,STIL,STK4,SUFU,SULF2,T,TAB1,TAF8,TANC2,TAPT1,TBC1D32,TBX1,TBX15,TBX3,TBX6,TCF15,TCOF1,TEAD2,TFAP2A,TFEB,TGFB1,TGFB2,TGFBR1,TGFBR2,THOC2,TIE1,TLE6,TMED2,TMEM100,TMEM107,TMEM231,TRAF3IP1,TRAF6,TRIM28,TRIM71,TSC2,TTPA,TULP3,TWIST1,UBTFL1,VANGL2,VASH1,VASH2,VASP,VEGFA,WDR60,WDTC1,WNT1,WNT11,WNT3A,WNT5A,WNT7B,WNT8A,WNT9A,WNT9B,XAB2,XRCC2,YBX1,YBX3,ZEB1,ZFAND5,ZFAT,ZFP36L1,ZFPM2,ZMIZ1,ZNF335,ZNF358,ZNF830,ZP3,ZPR1	TetrapodAncestor	152.652
GO.Biological.Process	GO:0070663	regulation.of.leukocyte.proliferation	163	2.350663e-157	3.036351e-153	1.862792e-155	1.334216e+0	ADA,AGER,AHR,AIF1,ANXA1,ARG1,ARG2,ATAD5,ATM,BCL2,BCL6,BMP4,BST1,BTK,CARD11,CASP3,CCDC88B,CCL19,CCL5,CCL8,CCR2,CD1D,CD209,CD24,CD274,CD276,CD28,CD300A,CD320,CD38,CD3E,CD40,CD46,CD55,CD59,CD6,CD74,CD80,CD81,CD86,CDKN1A,CEBPB,CHRNB2,CLC,CLCF1,CLEC4G,CLECL1,CORO1A,CSF1,CTLA4,CTNNB1,DHPS,DLG1,DLG5,DNAJA3,EBI3,EFNB1,EPO,ERBB2,FADD,FGF10,FLT3LG,FOXJ1,FOXP3,GAL,GNRH1,GPAM,GPNMB,GPR183,GREM1,GSTP1,HAVCR2,HES1,HHLA2,HMGB1,IDO1,IFNG,IGF1,IGF2,IGFBP2,IHH,IKZF3,IL10,IL12A,IL12B,IL12RB1,IL13,IL15,IL18,IL1B,IL2,IL20RB,IL21,IL23A,IL23R,IL27,IL4,IL5,IL6,IL6ST,IL7,INPP5D,IRF1,IRS2,ITCH,JAK3,KITLG,LEP,LGALS3,LGALS9,LILRB2,LRRC32,LST1,LYN,MAD1L1,MEF2C,MIF,MZB1,NCK1,NCK2,NCKAP1L,NDFIP1,NFATC2,OCSTAMP,PAWR,PDCD1LG2,PDE5A,PELI1,PKN1,PLA2G2D,PLA2G2F,PNP,PRDM1,PRKAR1A,PRKCQ,PTH,PTPN22,PYCARD,RAC2,RASAL3,RC3H1,RIPK2,RIPK3,RPS3,SASH3,SCGB1A1,SDC4,SELENOK,SLC39A10,SOS1,SOX11,SPN,SYK,TAC1,TFRC,TGFB1,TGFBR2,TICAM1,TIRAP,TLR4,TLR9,TMEM131L,TMIGD2,TNFAIP3,TNFRSF13B,TNFRSF13C,TNFRSF14,TNFRSF21,TNFRSF4,TNFSF13B,TNFSF18,TNFSF9,TRAF6,VAV3,VCAM1,VSIG4,VTCN1,WNT3A,XCL1,ZAP70,ZNF335,ZP3,ZP4	TetrapodAncestor	152.518
GO.Biological.Process	GO:0045596	negative.regulation.of.cell.differentiation	164	2.398786e-157	3.098512e-153	1.889337e-155	1.161318e+0	ABCA1,ABCA5,ABCC8,ABCG1,ACTN4,ACVRL1,ADAMTS12,ADAMTS7,ADCYAP1,ADGRG1,ADIPOQ,ADIPOR1,ANKRD17,ANKRD2,ANKRD26,ANXA1,AP1AR,APOE,APP,AREG,ARF6,ARHGAP4,ARHGDIA,ARHGEF2,ARNTL,ASAP1,ASCL1,ASCL2,ASPM,ASXL1,AXIN2,BBS12,BCL11A,BCL2,BCL6,BDNF,BHLHA15,BHLHE41,BMP2,BMP4,BMP5,BMP7,BMPR1A,BRINP1,C16orf45,C1QC,C1QL4,CALR,CARM1,CARTPT,CAV1,CAV3,CBFA2T2,CCDC85B,CCL17,CCL3,CCND1,CD74,CDC73,CDK13,CDK5,CDK5R1,CDK5RAP2,CDK6,CERS2,CETP,CFLAR,CHRD,CIB1,CITED1,CLDN18,CMTM5,CNTF,CNTN2,CNTN4,COL3A1,COL5A1,COL5A2,CRMP1,CTDP1,CTDSP1,CTLA4,CTNNA1,CTNNB1,CTSZ,CUL4A,CXCL10,CXCL14,DAB1,DAB2IP,DACT3,DCC,DGUOK,DISP3,DIXDC1,DKK1,DLL1,DLL3,DMTN,DPYSL3,DRAXIN,DRD3,DTX1,DUSP10,DYNLT1,E2F1,EDNRB,EFEMP1,EFNA1,EFNA5,EFNB2,EFNB3,EGFR,EID2B,EIF2AK4,EIF4E,EIF4ENIF1,ELF5,ENPP1,EPHA4,EPHA7,EPHB1,EPHB2,ERBB2,ERBB4,EREG,ESRRB,EZH2,F2,FAM57B,FAM60A,FBLN1,FBXO7,FGF10,FGF13,FGF23,FKBP4,FOXA1,FOXA2,FOXE3,FOXG1,FOXJ1,FOXO1,FOXO4,FOXP3,FRS2,FSTL3,FSTL4,FUOM,FUZ,FZD7,G6PD,GABPA,GAK,GAL,GATA2,GATA3,GDF10,GDF11,GDF3,GDF5,GDI1,GFAP,GLI2,GLI3,GNRH1,GPER1,GPR171,GPR37L1,GPR55,GPR68,GREM1,GRHL2,GSK3A,HAND2,HDAC2,HDAC4,HDAC5,HDAC7,HDAC8,HES1,HES5,HEY2,HIST1H4J,HIST1H4K,HIST1H4L,HIST2H4B,HIST4H4,HLX,HMG20A,HMGB1,HMGB3,HNRNPU,HOOK3,HPN,HSPA9,IAPP,ID1,ID2,ID3,ID4,IDH2,IFNA2,IFNB1,IFNG,IFNL1,IFRD1,IGF1,IGFBP5,IHH,IL13,IL18,IL2,IL4,IL6,INHA,INHBA,INPP5D,INPP5J,IRF1,ISL1,ITGAV,ITGB1,ITM2C,ITPKB,JAG1,JAK3,KANK1,KIAA0319,KLF13,KRAS,LBH,LBX1,LDLRAD4,LEO1,LGALS1,LILRB4,LIMD1,LIN28A,LINGO1,LMX1A,LOXL3,LPAR1,LRIG2,LRP1,LRP4,LRP5,LRRC17,LSM1,LYN,MAD2L2,MAFB,MAG,MAP4K4,MAPK1,MBD1,MBNL3,MCF2,MDM2,MECP2,MED28,MEIS1,MEIS2,MELTF,MEN1,MESP1,MIB1,MIXL1,MMP11,MSTN,MSX1,MSX2,MYC,MYCN,MYOCD,NBR1,NEPRO,NF1,NFATC4,NFKBID,NGEF,NGFR,NKX2-5,NKX3-2,NKX6-1,NLGN1,NLGN3,NME1,NME2,NMRK2,NOCT,NOG,NOTCH1,NOTCH3,NOTCH4,NOV,NPHP3,NPPC,NPR2,NR0B1,NR1H2,NR1H3,NRG1,NRG3,NRP1,NTRK3,OLIG2,OMG,OSR1,OSTN,OVOL2,PAEP,PAF1,PAFAH1B1,PAK1,PBLD,PBX1,PCM1,PDGFB,PF4,PGLYRP1,PGLYRP2,PGLYRP3,PHOX2B,PIK3R1,PKP2,PLK2,PLXNA3,PMP22,PPARA,PPARD,PPARG,PPP3CA,PRAMEF1,PRAMEF12,PRAMEF14,PRAMEF19,PRAMEF20,PRICKLE1,PRMT1,PRMT5,PRPF19,PSEN1,PTCH1,PTEN,PTH,PTHLH,PTK2,PTK2B,PTN,PTPRG,PTPRO,PTPRS,RAB29,RANBP3L,RAP1GAP2,RAPGEF2,RARA,RARB,RARG,RBPJ,RBPMS2,RC3H1,RCC2,REG3A,REG3G,REST,RFLNB,RGMA,RIOX1,RIT2,RNF10,RNF6,RORB,RTN4,RTN4R,RTN4RL2,RUFY3,RUNX1T1,S100B,S1PR3,SDHAF2,SEMA3A,SEMA3G,SEMA4D,SEMA5A,SFRP1,SFRP2,SHB,SIRT1,SIRT2,SIX2,SKI,SKIL,SKOR2,SLC6A4,SLIT2,SMAD4,SMAD7,SMO,SNAI1,SNAI2,SNAPIN,SOCS5,SORL1,SOSTDC1,SOX10,SOX11,SOX17,SOX2,SOX3,SOX8,SOX9,SPOCK1,SPP1,SRGAP2,SRGAP2C,SRSF6,STAP1,STAT1,STMN2,STRAP,STX1B,SUFU,SYNGAP1,SYT4,TACSTD2,TBX1,TBX3,TBX5,TBX6,TERT,TGFB1,TGFB1I1,TGFB2,TGFBR1,THOC2,THY1,TJP2,TLR3,TLR4,TLX2,TLX3,TMEM131L,TMEM176A,TMEM176B,TMEM178A,TMEM64,TNF,TNFRSF8,TNFSF18,TNN,TNR,TP53INP1,TP63,TP73,TRAK2,TRIB1,TRIB2,TRIB3,TRIM11,TRIM6,TRIM62,TRIM72,TRIO,TRPC5,TRPC6,TRPM4,TRPV1,TSPO,TTPA,TUNAR,TWIST1,TWIST2,UBASH3B,UBE3A,UCMA,ULK2,USH2A,VHLL,VIM,WDR61,WEE2,WNT1,WNT10B,WNT3,WNT3A,WNT4,WNT5A,WNT7A,WNT9A,WWTR1,XBP1,XDH,YBX1,YWHAH,ZBTB16,ZC3H8,ZEB1,ZFP36,ZFP36L1,ZFP36L2,ZFPM1,ZFPM2,ZHX2,ZNF365,ZNF675	TetrapodAncestor	152.509
GO.Biological.Process	GO:0051216	cartilage.development	165	3.349874e-157	4.327032e-153	2.622444e-155	1.327586e+0	ALX1,AMELX,AXIN2,BARX2,BMP1,BMP2,BMP4,BMP5,BMP6,BMP7,BMP8A,BMP8B,BMPR1A,BMPR1B,BMPR2,CD44,CER1,CHI3L1,CHRDL2,CHST11,CNMD,COL10A1,COL11A1,COL1A1,COL27A1,COL2A1,CREB3L2,CSGALNACT1,CTGF,CYR61,CYTL1,EDN1,EIF2AK3,ENSG00000243696,ESRRA,EVC,FGF18,FGF2,FGF4,FGF6,FGF9,FGFR1,FGFR3,GDF2,GDF5,GLI2,GNAS,GPLD1,HAND1,HAND2,HES5,HIF1A,HMGA2,IHH,IL17F,IMPAD1,ITGB8,LRP6,LUM,MAPK14,MAPK3,MATN1,MEF2C,MEF2D,MEX3C,MGP,MKKS,MMP13,MSX1,MSX2,MUSTN1,MYCN,NFIB,NOG,NOV,NPPC,OSR1,OTOR,PAX7,PITX1,PKD1,POC1A,PRRX1,PTH1R,RARA,RARB,RARG,ROR2,RSPO2,RUNX1,RUNX2,SATB2,SCX,SERPINH1,SFRP2,SHOX2,SIX2,SMAD5,SNAI1,SNAI2,SNX19,SOX9,SRF,STC1,SULF2,TAPT1,TGFB1,TGFBI,TGFBR2,THBS3,THRA,TIMP1,TMEM110-MUSTN1,TRIP11,TYMS,WNT10B,WNT5A,WNT7A,WNT7B,ZBTB16,ZEB1	TetrapodAncestor	152.364
GO.Biological.Process	GO:0032872	regulation.of.stress-activated.MAPK.cascade	166	3.374375e-157	4.358680e-153	2.625711e-155	1.300605e+0	AGER,AIDA,AMBP,ANKRD6,APP,ARL6IP5,BMP2,CAV3,CCL19,CCL21,CCR7,CD27,CDC42,CTGF,DAB2IP,DACT1,DAXX,DBNL,DKK1,DLG1,DNAJA1,DTNBP1,DUSP10,DUSP15,DUSP19,DUSP22,DUSP3,DVL3,EDA2R,EDAR,EDN1,EGFR,EIF2AK2,EPHA4,EPHB1,ERCC6,ERN1,ERN2,EZR,F2RL1,FAS,FGD2,FGF19,FKTN,FLT4,FOXM1,FOXO1,FZD10,FZD4,FZD5,FZD7,FZD8,GADD45A,GADD45B,GADD45G,GDF6,GRIK2,GSTP1,HACD3,HAND2,HDAC3,HGF,HIPK2,HMGB1,HMGCR,HRAS,HSPH1,IGBP1,IGF1R,IL1B,IL26,INAVA,ITCH,KARS,LEP,LTBR,MAGI3,MAP2K2,MAP2K4,MAP2K7,MAP3K10,MAP3K11,MAP3K2,MAP3K21,MAP3K3,MAP3K4,MAP3K5,MAP3K6,MAP3K7,MAP3K9,MAP4K1,MAP4K4,MAPK1,MAPK3,MAPK8IP1,MAPK8IP3,MARVELD3,MECOM,MEN1,MID1,MINK1,MUL1,MYC,NBR1,NCF1,NOD1,NRK,OPRK1,PAFAH1B1,PAK1,PBK,PDCD10,PER1,PHLPP1,PINK1,PKN1,PLCB1,PPEF2,PRDX1,PRKN,PRMT1,PTK2B,PTPN1,PTPN22,PYCARD,RAP2A,RAPGEF1,RASGRP1,RASSF2,RB1CC1,RIPK1,RIPK2,ROR2,RPS3,SASH1,SDCBP,SEMA4C,SERPINB3,SFRP1,SFRP2,SH3RF1,SPAG9,SYK,TAOK1,TAOK2,TGFB2,TIAM1,TIRAP,TLR3,TLR4,TLR6,TLR9,TNF,TNFRSF11A,TNFRSF19,TNFSF11,TNIK,TP73,TPD52L1,TRAF2,TRAF4,TRAF6,ULK4,UNC5CL,VANGL2,VEGFA,WNT16,WNT5A,WNT7A,WNT7B,XDH,ZC3H12A,ZNF622,ZNF675	TetrapodAncestor	152.361
GO.Biological.Process	GO:0042176	regulation.of.protein.catabolic.process	167	8.745657e-157	1.129677e-152	6.764530e-155	1.254686e+0	ADAM8,ADAM9,ADGRB1,ADRA2A,AGAP2,ALAD,AMER1,ANAPC1,ANAPC11,ANAPC16,ANAPC2,ANAPC4,ANAPC5,ANKIB1,APC,APOE,ARAF,ARIH1,ARNTL,ASB9,ATP13A2,ATPIF1,ATRAID,ATXN3,AURKA,AZIN1,AZIN2,BAG6,BANP,BARD1,BBS7,BCAP31,BRSK2,BTRC,C4BPA,C4BPB,CAV1,CAV3,CCAR2,CCDC22,CCNB1,CD81,CDC16,CDC20,CDC23,CDC26,CDC27,CDC42,CDK1,CDKN1B,CEBPA,CHEK2,CHFR,CLEC16A,CLU,COMMD1,CSNK1A1,CSNK1D,CSNK1E,CSNK2A1,CSNK2A3,CTSC,CUL1,DAB2,DAB2IP,DACT1,DDA1,DDB1,DDRGK1,DERL2,DERL3,DET1,DISC1,DVL1,ECSCR,EDEM1,EDEM2,EFNA1,EGF,EGFR,EGLN2,ENSG00000273734,EPHA4,EZR,FAF1,FAM83D,FBXL5,FBXO22,FBXO5,FBXW7,FHIT,FLNA,FMN2,FMR1,FOXO1,FURIN,FZR1,GABARAPL2,GBA,GGA1,GGA3,GIPC1,GJA1,GNA12,GPC3,GPLD1,GRIN2A,GRIN2C,GSK3A,HERPUD1,HGS,HSP90AB1,HSPBP1,IDE,IFNG,IL10,IL1B,IL33,INS,IRAK3,ITCH,KCNE2,KEAP1,LAMP3,LAPTM4B,LATS1,LDLR,LONRF1,LONRF2,LONRF3,LRIG2,LRP1,LRRK2,MAD2L1,MAD2L2,MDM2,MDM4,MSN,MTM1,MYLIP,N4BP1,NDFIP1,NEDD4L,NELL1,NKD2,NOP53,NOS2,NRDC,NRG1,NSF,NUB1,NUDT15,OAZ1,OAZ2,OAZ3,ODC1,OPHN1,OS9,PACSIN3,PANO1,PARK7,PBK,PDCL3,PHB,PIAS1,PIN1,PINK1,PKD1,PLK1,PLK2,PLK3,PML,PRICKLE1,PRKACA,PRKCG,PRKN,PSEN1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTEN,PTK2,PTK2B,PTPN3,PTTG1IP,RAB7A,RAD23A,RAD23B,RCHY1,RDX,RELA,RFWD2,RGN,RGP1,RHBDD3,RHBDF1,RIC1,RNF114,RNF125,RNF128,RNF138,RNF139,RNF14,RNF144A,RNF144B,RNF166,RNF180,RNF19B,RNF217,RNF40,RNF41,RPL11,RPL23,RPL5,RPS27A,RPS7,RYBP,SCO1,SDCBP,SEC22B,SERPINB12,SERPINE2,SF3B3,SGSM3,SGTA,SIRT2,SMAD7,SMARCC1,SMURF1,SNF8,SNX1,SNX12,SNX9,SOCS4,SOCS5,SORL1,SOX17,SOX9,STUB1,STX5,SUFU,SUMO1,SUMO2,SVIP,TAF1,TAF9,TIMP1,TIMP2,TIMP3,TIMP4,TIPARP,TLK2,TMTC3,TNF,TNFAIP3,TNFRSF1B,TNFSF12,TRIB1,TRIB2,TRIB3,TRIM32,TRIM39,UBAC2,UBC,UBE2C,UBE2D1,UBE2E1,UBE2G2,UBE2J1,UBE2V2,UBE3A,UBQLN1,UBQLN4,UBXN1,UCHL5,UFL1,UQCC2,USP13,USP14,USP25,VCP,VIP,VPS11,VPS28,VPS35,WDR91,WNT1,WNT10B,WNT5A,XBP1,YOD1,ZFAND2A	TetrapodAncestor	151.947
GO.Biological.Process	GO:0002009	morphogenesis.of.an.epithelium	168	9.201683e-157	1.188581e-152	7.074889e-155	1.197458e+0	ABL1,ACVRL1,ADAMTS16,AHI1,AJUBA,ALDH1A3,ALX1,APAF1,AR,AREG,ARHGAP12,ARHGAP35,ARID1A,ARL13B,ASTN2,B4GALT1,BBS4,BBS7,BCL10,BCL2,BMP2,BMP4,BMP5,BMP7,BTRC,C2CD3,C5orf42,CA2,CA9,CAMSAP3,CARMIL2,CASR,CCDC103,CCDC40,CCL11,CCM2,CD44,CDC42,CELSR1,CFL1,CITED1,COBL,COL5A1,CRYGS,CSF1,CSF1R,CSNK2B,CTNNB1,CTSH,CTSZ,CYR61,DCHS1,DDR1,DEAF1,DLC1,DLG1,DLG3,DLG5,DLL1,DLL4,DNAAF1,DVL1,DVL3,EDN1,EFNB2,EGF,EGFR,ENG,EPB41L5,EPHA2,EPHA4,EPHA7,ESR1,ESRP2,EYA1,FAT4,FEM1B,FGF1,FGF10,FGF2,FGF7,FGFR1,FGFR2,FLNA,FLRT3,FMN1,FOXA1,FOXC2,FOXE1,FOXF1,FOXF2,FOXH1,FOXN1,FOXN4,FOXQ1,FRAS1,FREM2,FRS2,FUZ,FZD1,FZD2,FZD3,FZD5,FZD6,GATA3,GATA4,GBX2,GDF2,GDNF,GLI2,GLI3,GNA13,GORAB,GPC3,GRB2,GREM1,GRHL2,GRHL3,GRSF1,GZF1,HAND1,HAND2,HBEGF,HES1,HES5,HESX1,HHEX,HIF1A,HNF1B,ID4,IFT172,IFT20,IFT52,IFT57,IGFBP5,IHH,IL10,IL6,INTU,ITGA5,JAG1,JAG2,KDF1,KDM2B,KDM5B,KDM6A,KIF20B,KIF26B,KLF4,KLHL3,KRAS,KRT16,KRT17,KRT25,KRT27,KRT6A,KRT71,LAMA5,LBX1,LEF1,LGR4,LGR5,LHX1,LHX2,LIN7C,LMO4,LRP5,LRP6,LUZP1,MEF2C,MEGF8,MESP1,MET,MIB1,MKKS,MKS1,MMP12,MMP14,MSN,MSX2,MTHFD1,MTHFD1L,MTSS1,MYC,MYCN,MYO9A,NDRG4,NFATC4,NKX2-5,NKX3-1,NOG,NOTCH1,NOTCH4,NOTO,NPHP3,NRP1,OPHN1,OSR1,OVOL2,PAFAH1B1,PAK1,PAX2,PAX8,PBX1,PCDH8,PDCD10,PDPN,PFN1,PGR,PHACTR4,PITX2,PKD1,PKD2,PLET1,PLXNA1,PLXNB2,PLXND1,PML,PODXL,PRICKLE1,PRKACA,PRKD2,PRKX,PROX1,PSEN1,PTCH1,PTK7,RALA,RARA,RARG,RASIP1,RBPJ,RDH10,RET,RHOC,RIPK4,RSPO2,RSPO3,RYR2,SCRIB,SDC4,SEC24B,SEMA3A,SEMA3C,SEMA3E,SEMA4C,SERPINB5,SETD2,SETDB2,SFRP1,SFRP2,SH3BP1,SHROOM3,SIX2,SKI,SLC9A3R1,SLIT2,SMAD4,SMO,SNAI1,SOCS3,SOS1,SOSTDC1,SOX10,SOX11,SOX17,SOX18,SOX4,SOX8,SOX9,SPINT1,SPRY1,SPRY2,SRC,SRF,ST14,STARD13,STIL,STK4,SUFU,SYNE4,T,TACSTD2,TBX2,TBX20,TBX3,TBX5,TCF15,TCF21,TEAD2,TFAP2A,TGFB1,TGFB1I1,TGFB2,TGFBR2,TGM2,TGM3,TIMELESS,TMED2,TMEFF2,TMEM79,TNC,TOR1A,TP63,TRAF3IP1,TRAF6,TRIM28,TRIM71,TSC2,TULP3,TWIST1,VANGL2,VASP,VCL,VDR,VEGFA,VEGFC,WDR1,WNK4,WNT1,WNT10A,WNT11,WNT16,WNT3A,WNT4,WNT5A,WNT6,WNT7A,WNT7B,WNT9B,ZIC3	TetrapodAncestor	151.925
GO.Biological.Process	GO:0043009	chordate.embryonic.development	169	1.608697e-156	2.077954e-152	1.229559e-154	1.179962e+0	ABI1,ABL1,ACVR1B,ACVR2A,ACVRL1,ADA,ADAR,ADD1,ALKBH1,ALS2,ALX1,ALX4,AMBRA1,AMOT,ANGPT1,APAF1,APBA1,APBA2,APBA3,APOB,AR,ARHGAP35,ARID1A,ARL13B,ARNT2,ASCL2,ATM,ATP6AP2,AXIN2,B9D1,BBS4,BCL10,BCL2L1,BCL2L11,BIRC6,BMP2,BMP4,BMP5,BMP7,BMPR1A,BMPR2,BRCA1,BYSL,C2CD3,C5,C6,CAPN2,CASP8,CCM2,CCNB1,CCNB1IP1,CDKN1C,CEBPA,CEBPB,CECR2,CELSR1,CENPU,CFL1,CHD7,CHD8,CHRD,CHST11,CITED1,CNOT2,CNOT3,COBL,COL11A1,COL1A1,COL2A1,COPS3,CRB2,CTNNB1,CUL3,CUL4A,CYR61,DACT1,DAD1,DCHS1,DEAF1,DKK1,DLC1,DLG1,DLL1,DLL3,DNAJB6,DSCAML1,DUSP3,DVL1,DVL3,E2F7,E2F8,EDN1,EGFR,EGLN1,EIF2S2,EIF4A3,EIF4E2,ELF3,EMX1,EN1,ENDOG,EOMES,EP300,EPAS1,EPB41L5,EPHA2,EPN1,ERCC2,ETNK2,EXT1,EYA1,FAM212A,FBXW8,FERD3L,FGF9,FGFR1,FGFR2,FLCN,FLVCR1,FOSL1,FOXA1,FOXC1,FOXC2,FOXF1,FUT8,FUZ,FZD1,FZD2,FZD3,FZD5,FZD6,GABPA,GATA2,GATA3,GATA6,GBX2,GCM2,GDF3,GGNBP2,GINS1,GINS4,GJB3,GJB5,GLI2,GLI3,GNA12,GNA13,GNAS,GRB2,GRHL2,GRHL3,GSC,HAND1,HAND2,HEG1,HES1,HES3,HES5,HES7,HEY1,HEY2,HHEX,HIF1A,HINFP,HNF1B,HOXA1,HS6ST1,HSD17B2,HSF1,IFITM5,IFT140,IFT172,IFT52,IFT57,IGF2,IHH,IL10,INPP5B,INPP5K,INTU,ISL1,ITGB1,ITPK1,JAG2,JUNB,KBTBD8,KDM2B,KDM4C,KDM6A,KEAP1,KIAA1217,KIF20B,KLF2,KLHL12,KRT19,LATS1,LEF1,LFNG,LHX1,LHX2,LIF,LIG4,LMO4,LRP6,LUZP1,MAFF,MAFG,MAN2A1,MAPK1,MBD3,MBNL1,MBTD1,MDFI,MED21,MEF2C,MEGF8,MEOX1,MEOX2,MESP1,MESP2,MFN2,MIB1,MKS1,MMP14,MMP16,MSGN1,MSH2,MSX1,MTHFD1,MTHFD1L,MYCN,MYF6,MYH6,MYH9,MYO1E,NASP,NBN,NCAPG2,NCOA1,NDEL1,NDST1,NF1,NIPBL,NKX2-5,NKX2-6,NKX3-1,NKX3-2,NLE1,NMT1,NOG,NOLC1,NOS3,NOTCH1,NSDHL,OCRL,OOEP,OSR1,OVOL2,PALB2,PAX2,PAX5,PAX7,PBX1,PCDH12,PCDH8,PCGF2,PCSK5,PDCD6,PDGFB,PEF1,PFN1,PHACTR4,PITX2,PKD1,PKD2,PLAC1,PLCD3,PLCG1,PLG,PLK4,PLXNA2,PLXNB2,POGLUT1,POLG2,PRDM1,PRICKLE1,PRKACA,PRKDC,PROX1,PRPF19,PRRX1,PSEN1,PSMC3,PSMC4,PTCH1,PTK7,PTPRR,PYGO2,RALA,RARA,RARG,RARRES2,RBBP8,RBM46,RBP4,RBPJ,RDH10,RIC8A,RIPPLY1,RIPPLY2,RIPPLY3,RNASEH2B,ROR2,RPL7L1,RRN3,RRP7A,RSPO3,RTF1,RUNX2,RXRA,SALL2,SATB2,SBDS,SCRIB,SCX,SDC4,SEC24B,SEC24D,SEMA3C,SEMA4C,SETD2,SF3B6,SFRP1,SFRP2,SHOX2,SHROOM3,SIX2,SKI,SKIL,SLC30A1,SLC34A2,SLC39A3,SMAD2,SMAD4,SMO,SNAI1,SOCS3,SOX10,SOX11,SOX17,SOX18,SOX4,SOX8,SOX9,SPIC,SPINT1,SRF,SRSF1,SSBP3,ST14,STIL,STK4,SUFU,SULF2,T,TAB1,TAF8,TANC2,TAPT1,TBC1D32,TBX1,TBX15,TBX3,TBX6,TCF15,TCOF1,TEAD2,TFAP2A,TFEB,TGFB1,TGFB2,TGFBR1,TGFBR2,THOC2,TIE1,TMED2,TMEM100,TMEM107,TMEM231,TRAF3IP1,TRAF6,TRIM28,TRIM71,TSC2,TTPA,TULP3,TWIST1,UBTFL1,VANGL2,VASH1,VASH2,VASP,VEGFA,WDR60,WDTC1,WNT1,WNT11,WNT3A,WNT5A,WNT7B,WNT8A,WNT9A,WNT9B,XAB2,XRCC2,YBX1,YBX3,ZEB1,ZFAND5,ZFAT,ZFP36L1,ZFPM2,ZMIZ1,ZNF335,ZNF358,ZNF830,ZP3,ZPR1	TetrapodAncestor	151.682
GO.Biological.Process	GO:0019221	cytokine-mediated.signaling.pathway	170	3.403125e-156	4.395817e-152	2.585774e-154	1.251252e+0	ACKR2,ACKR3,ACKR4,ACSL1,ADAR,ADIPOQ,ADIPOR1,ADIPOR2,AIP,ARF1,ASPN,BAD,BAG4,BBS4,BGN,BIRC2,BIRC3,BOLA2B,BRWD1,BST2,CA1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CANX,CARD14,CCL1,CCL11,CCL13,CCL14,CCL15,CCL15-CCL14,CCL16,CCL17,CCL18,CCL19,CCL2,CCL21,CCL22,CCL23,CCL3,CCL3L3,CCL4,CCL4L2,CCL5,CCL7,CCL8,CCR1,CCR2,CCR3,CCR4,CCR5,CCR6,CCR7,CCR8,CCR9,CCRL2,CD27,CD300LF,CD40,CD44,CD70,CD74,CDC42,CDIP1,CEBPA,CFL1,CHAD,CHUK,CIB1,CIITA,CISH,CLCF1,CLDN18,CMKLR1,CNTF,CNTFR,COMMD7,CRLF2,CSF1,CSF1R,CSF2RA,CSF2RB,CSF3,CSF3R,CSNK2B,CX3CL1,CX3CR1,CXCL1,CXCL10,CXCL11,CXCL13,CXCL2,CXCL3,CXCL5,CXCL6,CXCL8,CXCL9,CXCR1,CXCR2,CXCR3,CXCR4,CXCR5,CXCR6,DCN,DUOX1,DUOX2,EBI3,EDA,EDA2R,EDAR,EDARADD,EDN2,EGR1,ELOC,ENSG00000249624,EPO,EPOR,EREG,F3,FAS,FER,FKBP1A,FLRT1,FLRT2,FLRT3,FOXC1,GHR,GP1BA,GPR17,GPR35,GRB2,GREM2,GSTA2,HCK,HIST1H3H,HIST1H3I,HIST1H3J,HIST2H3A,HIST2H3C,HIST2H3D,HNRNPA2B1,HSPA9,IFI27,IFI35,IFI6,IFIT1,IFIT2,IFIT3,IFITM1,IFITM2,IFITM3,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNAR1,IFNAR2,IFNB1,IFNE,IFNG,IFNGR1,IFNGR2,IFNK,IFNLR1,IFNW1,IKBKB,IL10,IL10RA,IL10RB,IL11RA,IL12A,IL12B,IL12RB1,IL12RB2,IL13RA1,IL13RA2,IL15,IL15RA,IL17RA,IL17RB,IL17RC,IL17RD,IL17RE,IL17REL,IL18,IL18R1,IL18RAP,IL1A,IL1B,IL1F10,IL1R1,IL1R2,IL1RAP,IL1RAPL2,IL1RL1,IL1RL2,IL20RA,IL20RB,IL21R,IL22RA1,IL22RA2,IL23A,IL23R,IL27,IL27RA,IL2RB,IL2RG,IL31RA,IL36A,IL36B,IL36G,IL37,IL3RA,IL5,IL5RA,IL6,IL6R,IL6ST,IL7,IL7R,IL9,IRAK1,IRAK3,IRAK4,IRF1,IRF2,IRF3,IRF4,IRF6,IRF7,IRF8,IRF9,IRS1,IRS2,ISG15,ISG20,JAGN1,JAK2,JAK3,KARS,KRAS,LCK,LCP1,LEP,LEPR,LIFR,LMNB1,LRP8,LRRC15,LRRC19,LRRC3,LRRC3C,LRRC4,LRRC4C,LRRC66,LRRTM1,LRRTM3,LRRTM4,LRTM1,LRTM2,LTB,LTBR,MAP3K14,MAPK3,MID1,MIF,MKKS,MPL,MSN,MST1R,MTAP,MX1,MX2,NCAM1,NGFR,NMI,NUMBL,OAS1,OASL,OSM,OSMR,P4HB,PAK2,PDGFB,PF4,PF4V1,PIK3C3,PIK3CA,PIK3R1,PIK3R2,PITPNA,PLCB1,PLP2,PLVAP,PML,PODN,PODNL1,PPBP,PRKCD,PRLR,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTAFR,PTK2B,PYCARD,PYDC1,RALA,RAP1B,RELA,RELT,RIPK1,RNASEL,RPLP0,RPS27A,RPS6KA4,RPS6KA5,RSAD2,RTN4R,RTN4RL2,SAMHD1,SERPINB2,SHC1,SIRT1,SLC27A1,SMAD4,SMARCA4,SNRPA1,SOCS1,SOCS2,SOCS3,SOCS4,SOCS5,SOCS6,SOCS7,SOD1,SOD2,SP100,ST18,STAT1,STAT2,STAT4,STAT6,TALDO1,TCP1,THPO,TJP2,TNF,TNFRSF10A,TNFRSF10B,TNFRSF10C,TNFRSF10D,TNFRSF11A,TNFRSF11B,TNFRSF12A,TNFRSF13B,TNFRSF13C,TNFRSF14,TNFRSF17,TNFRSF18,TNFRSF19,TNFRSF1A,TNFRSF1B,TNFRSF21,TNFRSF25,TNFRSF4,TNFRSF8,TNFRSF9,TNFSF11,TNFSF12,TNFSF13,TNFSF13B,TNFSF14,TNFSF15,TNFSF18,TNFSF8,TNFSF9,TNIP2,TRADD,TRAF2,TRAF3,TRAF6,TRIM21,TRIM22,TRIM25,TRIM34,TRIM38,TRIM5,TRIM62,TRIM68,TRIM8,TSLP,TXNDC17,UBC,VCAM1,XAF1,XCL1,XCL2,XCR1,ZC3H15,ZNF675	TetrapodAncestor	151.357
GO.Biological.Process	GO:0002521	leukocyte.differentiation	171	3.771412e-156	4.871533e-152	2.848850e-154	1.274822e+0	ABL1,ADA,ADGRG3,AICDA,ANXA1,APP,ATG5,ATM,ATP11C,AXL,AZI2,BAK1,BATF2,BATF3,BAX,BCL11B,BCL2,BCL3,BCL6,BLNK,BMP4,BMX,BRAF,BTK,CAMK4,CARD11,CASP8,CBFB,CCL19,CCR6,CCR7,CCR9,CD109,CD1D,CD28,CD3D,CD3E,CD74,CD79B,CD86,CD8A,CDC42,CDK6,CEBPA,CEBPE,CEBPG,CHD7,CLCF1,CLEC4D,CLEC4E,CMTM7,CR2,CSF1,CSF1R,CSF3,CTNNB1,DCAF1,DCLRE1C,DHRS2,DLL1,DLL4,DNAJA3,DOCK10,DOCK11,DOCK2,EFNA4,EGR1,EOMES,EP300,EPHA2,F2RL1,FADD,FAM20C,FAS,FCER1G,FLT3LG,FOXN1,FOXP3,FUT7,FZD5,FZD7,FZD8,FZD9,GAB2,GAS6,GATA2,GATA3,GLI3,GLO1,GON4L,GPC3,GPR18,GPR183,HDAC4,HDAC5,HDAC9,HHEX,HMGB1,HNF1A,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNB1,IFNE,IFNG,IFNK,IFNW1,IKZF1,IL10,IL12B,IL15,IL18R1,IL2,IL31RA,IL4,IL6,IL7,IL7R,IRF1,IRF4,ITFG2,ITGA4,ITGB1,ITK,ITM2A,ITPKB,JAG2,JAGN1,JAK3,JMJD6,JUN,JUNB,KDELR1,KLF6,L3MBTL3,LCK,LEF1,LEP,LEPR,LFNG,LGALS1,LIG4,LRRC8A,LTBR,LY6D,LYL1,LYN,MAFB,MALT1,MAPK14,MEF2C,MERTK,MFNG,MMP9,MSH2,MYH9,NFAM1,NHEJ1,NKX2-3,NOTCH2,NTRK1,OCSTAMP,ONECUT1,OSTM1,PAFAH1B1,PARP1,PATZ1,PDE1B,PIK3CD,PIK3R1,PIR,PKNOX1,PLA2G2D,PLCG2,PLCL2,POLM,POU1F1,POU2F2,PPARG,PPP3CB,PREX1,PRKDC,PSEN1,PSMB11,PTGER4,PTK2B,PTPN22,RAG1,RAG2,RBPJ,RC3H1,RC3H2,RELB,RIPK3,RORC,RPS6,RRAS,RSAD2,RUNX2,SATB1,SEMA4A,SH3PXD2A,SIRT1,SLAMF6,SNX10,SOX4,SPI1,SPN,SRC,SRF,STAT6,SYK,TAL1,TCF3,TFRC,TGFB1,TGFBR2,THEMIS,THOC5,TLR2,TNF,TNFRSF11A,TNFSF11,TNFSF8,TPD52,TRAF6,TREM2,TRPM2,TSPAN2,TYRO3,VAV1,VCAM1,VEGFA,WNT1,WNT4,ZAP70,ZBTB1,ZFP36L1,ZFP36L2,ZFPM1,ZNF683	TetrapodAncestor	151.312
GO.Biological.Process	GO:2001233	regulation.of.apoptotic.signaling.pathway	172	7.846262e-156	1.013502e-151	5.892452e-154	1.270122e+0	ACAA2,ACKR3,ADORA2A,AGT,AGTR2,ANKRD2,APAF1,AR,ARHGEF2,ARRB2,ATF3,ATPIF1,AVP,BAD,BAK1,BAX,BCAP31,BCL10,BCL2,BCL2L1,BCL2L10,BCL2L11,BCL2L12,BCL2L2,BCL2L2-PABPN1,BCLAF1,BDKRB2,BID,BIK,BIRC6,BMP4,BMP5,BMPR1B,BNIP3,BRCA1,CASP2,CASP8,CAV1,CCAR2,CD44,CD74,CDKN2D,CFLAR,CIDEB,CLU,COL2A1,CRADD,CREB3,CREB3L1,CTH,CTNNA1,CTNNB1,CTSC,CTSH,CTTN,CX3CL1,CX3CR1,DAB2IP,DAPK1,DAPK2,DAPK3,DBH,DDIAS,DDX3X,DEDD2,DEPTOR,DFNA5,DNAJA1,DNM1L,DYNLL1,DYNLL2,E2F1,EIF2AK3,ELL3,EPO,ERP29,EYA1,EYA2,EYA3,EYA4,FADD,FAF1,FAIM2,FAM162A,FAS,FASLG,FBXO18,FBXW7,FEM1B,FGF10,FGFR1,FGG,FIGNL1,FIS1,FXN,FZD9,G0S2,GCLM,GDNF,GFRAL,GPER1,GRINA,GSK3A,GSN,GSTP1,HERPUD1,HGF,HIF1A,HIP1R,HMGB2,HMOX1,HNRNPK,HRK,HSPB1,HSPH1,HTRA2,HTT,HYOU1,IFI6,IFNB1,IGF1,IL19,IL1A,IL1B,IL20RA,IL4,IL7,INCA1,ING2,INHBA,INHBB,INS,ITGAV,ITM2C,IVNS1ABP,JAK2,KDM1A,LCK,LGALS3,LGALS9,LMNA,LRRK2,LTBR,MADD,MAPK8,MAPK8IP1,MAPK9,MDM2,MEIS3,MFF,MIF,MLLT11,MMP9,MNT,MPV17L,MSX1,MUC1,MUL1,NANOS3,NCK1,NCK2,NDUFS3,NF1,NFATC4,NKX3-1,NLE1,NME5,NMT1,NOC2L,NOG,NOL3,NOS3,NR4A2,NRP1,OPA1,OSM,P4HB,PAK2,PAK5,PARK7,PARP1,PCGF2,PDCD5,PDIA3,PDILT,PEA15,PELI3,PF4,PGAP2,PHIP,PIAS4,PIDD1,PIH1D1,PINK1,PLA2G6,PLEKHF1,PMAIP1,PML,PPIF,PPP1R13B,PPP2R1B,PPP3CC,PPP3R1,PRELID1,PRKCD,PRKN,PRKRA,PSEN1,PSMD10,PSME3,PTEN,PTPN1,PTTG1IP,PYCARD,RAD9A,RAF1,RB1CC1,RBCK1,RELA,RET,RFFL,RIPK1,RIPK3,RNF34,RPL11,RPS3,RPS7,RRM2B,RRN3,S100A8,S100A9,SCG2,SCRT2,SEPT4,SERINC3,SFN,SFPQ,SFRP1,SFRP2,SGMS1,SH3RF1,SIAH1,SIAH2,SIRT1,SKIL,SLC25A5,SLC35F6,SLC9A3R1,SNAI1,SNAI2,SOD1,SOD2,SP100,SPOP,SRC,SRPX,ST18,STK4,STRADB,STX4,SYVN1,TAF9,TAF9B,TERT,TFDP2,TGFBR1,THBS1,TIMP3,TMBIM1,TMBIM6,TMC8,TMEM14A,TMEM161A,TNF,TNFAIP3,TNFRSF10A,TNFRSF10B,TNFRSF12A,TNFSF10,TNFSF12,TP53,TP53BP2,TP53INP1,TP63,TP73,TPD52L1,TPT1,TRADD,TRAF1,TRAF2,TRAF7,TRAP1,TRIAP1,TRIM32,TRIM39,UBQLN1,UNC5B,USP47,VHLL,VNN1,WDR35,WFS1,WNT4,WWOX,XBP1,YBX3,YWHAB,YWHAE,YWHAG,YWHAH,YWHAZ,ZC3HC1,ZNF205,ZNF385A,ZSWIM2	TetrapodAncestor	150.994
GO.Biological.Process	GO:0045807	positive.regulation.of.endocytosis	173	8.898984e-156	1.149482e-151	6.644403e-154	1.443976e+0	ABR,ACTN4,AHI1,AHSG,ANGPT1,ANO6,APELA,APLN,APOA5,APOE,ARF1,ARRB1,ARRB2,ATAD1,AXL,BCR,BICD1,C3,C4A,C4B,CALR,CALY,CAMK1D,CAV3,CBL,CBLL1,CCL19,CCL2,CCL21,CD14,CD300LF,CD36,CD47,CD63,CLIP3,CYBA,DAB2,DLL1,DNM1L,DNM2,DOCK2,DRD2,EEF2K,EGF,F2RL1,FCER1G,FLOT1,FMR1,GAS6,GATA2,GPC3,GREM1,HIP1,HIST1H1A,HNRNPK,IL1B,ITGA2,ITGAV,LDLR,LDLRAP1,LMAN2,LRP1,MAGI2,MBL2,MERTK,MFGE8,MIB1,MYO18A,NCKAP1L,NEDD4L,NLGN1,NTF3,PICALM,PICK1,PLCG2,PPARG,PPP3CA,PPT1,PTX3,PYCARD,RAB21,RAB27A,RAP1A,RAPGEF1,SCYL2,SELE,SFRP4,SGIP1,SLC11A1,SNCA,SPACA3,STAP1,SYK,TBC1D5,TF,TFR2,TNF,TOR1A,TSG101,TUB,TULP1,VEGFA,VPS28,VTN,WNT3A,WNT5A	TetrapodAncestor	150.939
GO.Biological.Process	GO:0023014	signal.transduction.by.protein.phosphorylation	174	1.322847e-154	1.708721e-150	9.820238e-153	1.229502e+0	ACVR1B,ACVR2A,ACVR2B,ACVRL1,ADORA2B,AGT,AMHR2,ANGPT1,ARAF,ARTN,AVP,BMPR1A,BMPR1B,BMPR2,BRAF,BRAP,BTC,BTRC,CAB39,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CAMKK2,CASR,CCL11,CCL19,CCL2,CCL3,CCL5,CCM2,CCR5,CDC42EP5,CHUK,CLEC1B,CRKL,CRYAB,CSF2RA,CSF2RB,CTSH,CUL1,CUL3,DAB2IP,DAXX,DBNL,DLG4,DOK5,DUSP6,DUSP7,DUSP9,EGF,EGFR,ENSG00000283952,EPGN,ERBB2,ERBB4,ERCC6,EREG,ERN1,ERN2,FBXW11,FGF1,FGF10,FGF13,FGF16,FGF17,FGF18,FGF19,FGF2,FGF20,FGF22,FGF23,FGF3,FGF4,FGF6,FGF7,FGF9,FGFR1,FGFR2,FGFR3,FGFR4,FRS2,FRS3,GDNF,GFRA1,GFRA2,GFRA3,GFRA4,GPS1,GRB2,GRIN1,GRIN2A,GRIN2B,GRIN2C,GRIN2D,HACD3,HBEGF,HGF,HRAS,HSF1,HTR2B,IGF1,IKBKB,IKBKG,IL17RD,IL18,IL1B,IL2,IL2RB,IL2RG,IL31RA,IL3RA,IL5,IL5RA,INS,IQGAP3,IRAK1,IRAK4,IRS1,IRS2,ITGAV,ITPKB,JAK2,JAK3,KARS,KBTBD7,KCNH1,KCNH2,KCNH3,KCNH5,KCNH8,KITLG,KL,KRAS,KSR1,LAMTOR2,LAMTOR3,LAT,LGALS9,LRRK2,LYN,MAP2K2,MAP2K3,MAP2K4,MAP2K6,MAP2K7,MAP3K1,MAP3K10,MAP3K11,MAP3K12,MAP3K13,MAP3K14,MAP3K15,MAP3K19,MAP3K2,MAP3K21,MAP3K3,MAP3K4,MAP3K5,MAP3K6,MAP3K7,MAP3K7CL,MAP3K8,MAP3K9,MAP4K1,MAP4K3,MAP4K4,MAPK1,MAPK10,MAPK11,MAPK13,MAPK14,MAPK15,MAPK3,MAPK4,MAPK6,MAPK8,MAPK8IP1,MAPK8IP3,MAPK9,MAPKAPK2,MAPKAPK3,MAPKAPK5,MEF2A,MEF2C,MEN1,MET,MINK1,MOS,MUL1,MYC,NCAM1,NEFL,NEK1,NEK4,NF1,NFKB1,NLK,NOD1,NPHS1,NRAS,NRG1,NRG2,NRG4,NRK,NRTN,OSR1,OXTR,PABPN1,PAK2,PAK3,PAK4,PAK5,PDGFA,PDGFB,PDGFRB,PEA15,PKN1,PLVAP,PPM1L,PPP5C,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PSPN,PTGER4,PTK2,PTK2B,PTPN1,PTPRA,RAF1,RANBP9,RAPGEF2,RASA1,RASA2,RASA3,RASAL1,RASAL2,RASAL3,RASGEF1A,RASGRF1,RASGRF2,RASGRP1,RASGRP4,RET,RHBDD3,RIPK1,RIPK2,ROR2,ROS1,RPS27A,SBK2,SCG2,SETX,SH2D3A,SH2D3C,SHC1,SHC2,SHC3,SOS1,SOX9,SPAG9,SPRED1,SPTB,SPTBN2,SPTBN5,STK24,STK26,STK4,SYK,SYNGAP1,TAB1,TAB2,TAB3,TAOK1,TAOK2,TEK,TGFB1,TGFBR1,TGFBR2,TMEM189-UBE2V1,TNF,TNFRSF19,TNFSF11,TNIK,TNIP2,TPR,TRAF6,TRIB1,TYRO3,UBC,UBE2N,WDR83,WNK1,WNT5A,WNT7B,YWHAB,YWHAE,ZFP36,ZFP36L1,ZFP36L2	TetrapodAncestor	149.767
GO.Biological.Process	GO:0045732	positive.regulation.of.protein.catabolic.process	175	1.419256e-154	1.833253e-150	1.047573e-152	1.311475e+0	ADAM8,ADAM9,ADRA2A,AMER1,ANAPC1,ANAPC11,ANAPC16,ANAPC2,ANAPC4,ANAPC5,ANKIB1,APC,APOE,ARIH1,ASB9,ATPIF1,ATXN3,AURKA,BAG6,BARD1,BBS7,BCAP31,BTRC,C4BPA,C4BPB,CAV1,CAV3,CCDC22,CCNB1,CD81,CDC16,CDC20,CDC23,CDC26,CDC27,CDK1,CDKN1B,CEBPA,CHFR,CLU,CSNK1A1,CSNK1D,CSNK1E,CSNK2A1,CSNK2A3,CTSC,CUL1,DAB2,DAB2IP,DACT1,DDB1,DDRGK1,DET1,DISC1,DVL1,ECSCR,EDEM1,EDEM2,EGF,EGLN2,ENSG00000273734,EZR,FBXL5,FBXO22,FBXO5,FBXW7,FMR1,FOXO1,FURIN,FZR1,GBA,GGA1,GGA3,GJA1,GPC3,GPLD1,GSK3A,HERPUD1,HSPBP1,IDE,IFNG,IL1B,IL33,ITCH,KCNE2,KEAP1,LDLR,LONRF1,LONRF2,LONRF3,LRP1,LRRK2,MAD2L1,MDM2,MSN,MYLIP,NDFIP1,NEDD4L,NKD2,NOP53,NRDC,NSF,NUB1,OAZ1,OAZ2,OAZ3,PACSIN3,PIAS1,PLK1,PLK2,PLK3,PRICKLE1,PRKN,PSEN1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTEN,PTK2,PTK2B,PTTG1IP,RAB7A,RAD23A,RCHY1,RDX,RFWD2,RGN,RHBDD3,RNF114,RNF125,RNF128,RNF138,RNF139,RNF14,RNF144A,RNF144B,RNF166,RNF180,RNF19B,RNF217,RNF40,RNF41,RPS27A,SEC22B,SGSM3,SGTA,SIRT2,SMAD7,SMURF1,SNF8,SNX1,SNX9,SOCS4,SOCS5,SORL1,SOX17,SOX9,STUB1,STX5,SUMO1,SUMO2,TAF1,TIPARP,TMTC3,TNF,TNFAIP3,TNFRSF1B,TNFSF12,TRIB1,TRIB2,TRIB3,TRIM32,UBC,UBE2C,UBE2D1,UBE2E1,UBE2V2,UBQLN1,UQCC2,USP13,VCP,VIP,VPS11,VPS28,VPS35,WNT5A,XBP1,ZFAND2A	TetrapodAncestor	149.737
GO.Biological.Process	GO:0071417	cellular.response.to.organonitrogen.compound	176	1.430423e-152	1.847677e-148	1.049817e-150	1.200782e+0	AANAT,ABCB4,ABL1,ACTR2,ADCY2,ADCY3,ADCY4,ADCY5,ADCY8,ADIPOQ,ADRB2,AGT,AGTR1,AGTR2,AGTRAP,AHCYL1,AIF1,AKAP6,AKR1B1,AKT2,AOC1,AP3S1,APC,APEX1,APLP1,APOBEC1,APP,APPL1,AQP1,AQP8,ARG1,ARHGEF2,ARID1B,ATF4,ATP2B4,ATP6AP1,ATP6V0A4,ATP6V0B,ATP6V0C,ATP6V0D1,ATP6V0D2,ATP6V0E1,ATP6V0E2,ATP6V1B1,ATP6V1B2,ATP6V1C1,ATP6V1C2,ATP6V1D,ATP6V1E1,ATP6V1E2,ATP6V1G1,ATP6V1G3,ATP6V1H,BAD,BAIAP2L2,BCAR1,BCL11A,BCL2L1,BRCA1,BRIP1,C2CD5,CA2,CACNA1A,CACNA1S,CACNA2D1,CACNB1,CAMK2A,CAPN10,CAPN2,CASP3,CASP4,CASP6,CASQ2,CASR,CASTOR1,CAV1,CAV2,CAV3,CCL2,CCNA2,CD36,CDC5L,CDC6,CDH1,CDK4,CDK5,CEBPB,CFLAR,CFTR,CIB2,COL16A1,COL1A1,COL1A2,COL3A1,COL5A2,COL6A1,CPEB1,CPEB2,CPEB4,CPS1,CREB1,CRHBP,CRHR1,CRHR2,CRK,CSH1,CSK,CTNNA1,CTNNB1,CYBA,CYBB,CYFIP1,DDC,DDX11,DENND4C,DIAPH1,DMTN,DNM2,DNMT3A,DRD1,DRD5,EDN1,EEF2K,EGFR,EGR1,EIF4EBP1,ENPP1,ENSG00000278139,EPHA4,ERRFI1,EZH2,EZR,FDX1,FER,FGF21,FIS1,FOXC2,FOXO1,FOXO4,GAB1,GABPA,GABRB1,GABRB2,GABRB3,GABRG2,GCGR,GCK,GCLM,GH1,GH2,GHR,GHRHR,GHSR,GLP1R,GLP2R,GLRA1,GLRA2,GNB2,GNG10,GNG11,GNG12,GNG13,GNG2,GNG3,GNG7,GNG8,GNRHR,GOT1,GPD1,GPER1,GPLD1,GRB2,GRM5,GSK3A,GSTM2,GSTP1,HCN1,HCN2,HCN3,HCN4,HDAC2,HDAC5,HDAC8,HDAC9,HNRNPD,HSF1,HSP90B1,HSPA5,HTR1B,ID1,IDE,IGF1,IGF1R,IGF2,IGFBP5,IL6,INHBB,INPP5K,INS,IPO5,IRS1,IRS2,IRS4,ITPR2,JAK2,JAK3,JUP,KAT2B,KCNE1,KCNJ11,KCNQ1,KDM1A,KL,KLF1,KLF10,KLF11,KLF15,KLF2,KLF3,KLF4,KLF5,LAMTOR2,LAMTOR3,LAMTOR4,LARP1,LARS,LPIN1,LRP1,LRRK2,LYN,MAPK1,MAPK3,MAS1,MAX,MDM2,MEF2C,MEN1,MGARP,MSX1,MTOR,NDEL1,NEURL1,NFKB1,NGFR,NKX6-1,NOD1,NOX4,NR1H4,NR4A1,NR4A2,NR4A3,NTRK1,NTRK2,OPA1,OPRM1,P2RX4,PAK1,PARP1,PCK1,PDE2A,PDE3A,PDE4B,PDE4D,PDGFC,PDGFD,PDK2,PDPK1,PDXP,PENK,PHIP,PIK3C2A,PIK3CA,PIK3CG,PIK3R1,PIK3R2,PIK3R3,PKD2,PKLR,PKM,PLA2G1B,POR,PPARG,PPARGC1A,PPP1R9B,PRKAA1,PRKACA,PRKACG,PRKAR1A,PRKAR1B,PRKAR2B,PRKCD,PRKCI,PRKCZ,PRKDC,PRKN,PRL,PRLR,PSEN1,PTAFR,PTEN,PTK2,PTPN1,PTPN22,PTPRA,PXN,RAB13,RAB31,RAB8A,RAD51,RAP1A,RAP1B,RAPGEF1,RAPGEF2,RAPGEF3,RECQL5,RELA,RHOQ,RIPK2,RPE65,RPL23,RPTOR,RRAGA,RRAGD,RYR1,RYR2,RYR3,SESN2,SESN3,SFRP1,SH2B2,SH3BP4,SHC1,SHMT1,SIRT2,SLC25A33,SLC26A3,SLC2A8,SLC30A10,SLC34A1,SLC38A9,SLC5A5,SLC6A4,SLC8A1,SLC8A3,SLC9A1,SLIT2,SMARCC1,SNCA,SOCS1,SOCS2,SOCS7,SOD1,SOGA1,SORBS1,SOS1,SOX9,SP1,SPAAR,SPIDR,SRC,SRD5A1,SREBF1,SRSF5,STAR,STC1,STXBP4,TAF1,TBC1D4,TCIRG1,TGFB1,TH,TIMELESS,TLR4,TLR6,TNF,TP53,TREM2,TRIB3,TRPM2,TRPV1,TSHR,TUSC5,UBR1,UBR2,UCP2,UMODL1,USF1,VAMP2,WDTC1,WNT1,WNT10B,XBP1,XRN1,YWHAG,ZEB1,ZFP36L1,ZNF106	TetrapodAncestor	147.733
GO.Biological.Process	GO:0048870	cell.motility	177	1.525799e-152	1.970875e-148	1.113488e-150	1.139065e+0	AAMP,ABI2,ABL1,ACVRL1,ADAM8,ADAM9,ADAMTS12,ADCY3,ADGRA2,ADGRE2,ADGRG1,ADGRL3,AGTR1,AJUBA,AKAP4,ALKBH1,ALX1,AMOT,AMOTL1,ANGPT1,ANGPT2,ANGPT4,ANLN,ANO6,ANXA1,APBB2,APC,APCDD1,APELA,APOA1,APOB,ARC,ARF4,ARHGAP35,ARHGEF16,ARID5B,ARL13B,ARPC5,ARRB2,ARTN,ARX,ASAP3,ASCL1,ASH1L,ASPM,ASTN1,ATOH1,ATP1A4,ATP1B1,ATP1B2,ATP1B3,ATP2B4,AUTS2,AVL9,AXL,B4GALT1,BAMBI,BARHL1,BAX,BBS4,BCAR1,BCL11B,BDKRB1,BIN3,BLK,BRAT1,BSG,BTG1,C16orf45,C3AR1,C5,CACNA1I,CAP1,CARMIL1,CARMIL2,CATSPER1,CATSPER2,CATSPER4,CATSPERD,CATSPERZ,CAV1,CCDC40,CCDC88A,CCK,CCKAR,CCL1,CCL11,CCL13,CCL14,CCL15,CCL15-CCL14,CCL16,CCL17,CCL18,CCL19,CCL2,CCL21,CCL22,CCL23,CCL27,CCL28,CCL3,CCL3L3,CCL4,CCL4L2,CCL5,CCL7,CCL8,CCNYL1,CCR1,CCR2,CCR4,CCR5,CCR6,CCR7,CD151,CD2,CD24,CD2AP,CD34,CD44,CD47,CD58,CD63,CD74,CDC42,CDC42BPA,CDC42BPB,CDH13,CDH2,CDK1,CDK5,CDK5R1,CDK5R2,CDKL5,CELF3,CELSR1,CEND1,CER1,CFAP157,CFAP44,CFAP54,CFL1,CH25H,CHGA,CHL1,CKLF,CLRN1,CNR2,CNTN2,COL1A1,COL1A2,COL5A1,CORO1A,CORO1B,CRB2,CSF3R,CSPG4,CTGF,CTNNA2,CTNNB1,CTTN,CUL3,CUZD1,CX3CL1,CX3CR1,CXADR,CXCL1,CXCL10,CXCL11,CXCL13,CXCL14,CXCL16,CXCL2,CXCL3,CXCL5,CXCL6,CXCL8,CXCL9,CXCR1,CXCR2,CXCR3,CXCR4,CXCR5,CYP1B1,CYR61,DAB1,DAB2IP,DAPK2,DBH,DCC,DCDC2,DCHS1,DCX,DDIT4,DDR1,DDX4,DEPDC1B,DGKZ,DISC1,DIXDC1,DMRT1,DNAAF2,DNAH1,DNAH17,DNAH2,DNAH3,DNAH5,DNAH6,DNAH7,DNAH8,DNAI1,DNAJA1,DNER,DOCK4,DOCK8,DOK2,DRC1,DRD1,DRD2,DST,EDN2,EDN3,EDNRB,EFHC1,EFNA1,EFNB1,EFNB2,EGFR,EGR3,ELMO1,ELMO2,ELMO3,ELP3,EMILIN1,EMP2,EMX2,ENG,ENPEP,ENPP2,EPB41L5,EPCAM,EPHA2,EPHA3,EPHA4,EPHA8,EPHB1,EPHB3,EPHB4,EPS8,EPX,ERBB4,ERG,ESAM,ETS1,F11R,F2,F2RL1,FAM83D,FAT1,FAT2,FBXO45,FCAMR,FCER1G,FER,FERMT1,FES,FEZF1,FFAR2,FGF10,FGF13,FGF19,FGF2,FGFR1,FGFR4,FGR,FLNA,FLRT3,FLT1,FMNL1,FMNL3,FN1,FOXC1,FOXE1,FOXG1,FOXJ1,FOXN1,FRK,FSCN1,FSCN3,FUT10,FUT7,FUT8,FZD3,GAB1,GAPDHS,GAS6,GAS8,GATA2,GATA3,GBF1,GBX2,GDNF,GFRA3,GIPC1,GLG1,GLI3,GOLPH3,GP6,GPC1,GPC6,GPLD1,GPM6A,GPR15,GPR183,GPR32,GPR33,GRAP,GRAP2,GRB2,GRB7,GREM1,GSK3A,GYPC,HAND2,HBEGF,HCK,HES1,HGF,HIF1A,HMGB1,HMGB2,HRAS,HSD3B7,HTR2B,HTR6,ID1,IFNG,IGLL1,IL10,IL12A,IL12B,IL16,IL17RA,IL17RC,IL1B,IL6,IL6R,ING2,INPP5B,INPP5D,INSL6,INTS13,IRAK4,ISL1,ITGA1,ITGA11,ITGA2,ITGA3,ITGA4,ITGA5,ITGA9,ITGAM,ITGAV,ITGAX,ITGB1,ITGB2,ITGB4,ITGB7,JAGN1,JAK2,JAK3,JAM2,JAM3,JAML,JCHAIN,JMY,JUP,KALRN,KCTD13,KIAA0319,KIRREL3,KITLG,KRAS,KRT16,KRT2,L1CAM,LAMA5,LAMB1,LBP,LCK,LCP1,LDHC,LEF1,LEP,LGALS3,LGALS8,LHX1,LHX6,LIMD1,LOXL2,LPAR1,LRP5,LRRC6,LRRK2,LTB4R2,LURAP1,LY6K,LYN,MADCAM1,MAG,MARK1,MARK2,MATN2,MBOAT7,MCOLN2,MDGA1,MDK,MEF2C,MEGF10,MEGF8,MERTK,MESP1,MIF,MIXL1,MMP1,MMP12,MMP14,MMP9,MSN,MSX2,MYH9,MYO18A,MYO1G,NANOS1,NCK1,NCK2,NCKAP1L,NDEL1,NDNF,NDRG4,NET1,NEURL1,NEUROD4,NFATC2,NHSL1,NKX2-3,NKX6-1,NME8,NOS3,NOTCH1,NOV,NPHP4,NR4A1,NR4A2,NRAS,NRDC,NRG1,NRG3,NRP1,NRTN,NTRK2,NTRK3,NUP188,NUP85,OGDH,OLIG3,OLR1,OPHN1,OVOL2,P2RY1,PAFAH1B1,PAK2,PAK3,PAK4,PAK5,PALLD,PARP9,PAXIP1,PCM1,PDCD10,PDE4B,PDE4D,PDGFB,PDGFRB,PDILT,PDPK1,PDPN,PEAK1,PECAM1,PEX13,PEX7,PF4,PF4V1,PGK2,PHACTR1,PHACTR4,PHOX2B,PIH1D3,PIK3C2A,PIK3C2B,PIK3C2G,PIK3CA,PIK3CD,PIK3CG,PIK3R1,PIK3R2,PIP5K1A,PIP5K1C,PITX2,PKN1,PLA2G1B,PLA2G3,PLAT,PLAU,PLCG1,PLD1,PLD2,PLEKHG5,PLEKHO1,PLET1,PLG,PLPP1,PLPP3,PLTP,PLXNA2,PLXNB1,PLXND1,PML,PODXL,PODXL2,POMGNT2,POU3F2,POU3F3,POU4F1,PPARD,PPBP,PPIL2,PPP1R9B,PREX1,PRKCD,PRKCI,PRKCQ,PRKCZ,PRKG1,PRKX,PRM3,PROC,PROCR,PROP1,PROS1,PROX1,PRPF40A,PRSS3,PSEN1,PSTPIP2,PTEN,PTK2,PTK2B,PTK7,PTP4A3,PTPN11,PTPRK,PTPRO,PXN,RAB13,RAB1A,RAC1,RAPGEF2,RASGEF1A,RBFOX2,RELN,RERE,RET,RFX3,RHBDF1,RHOC,RHOG,RIC8A,ROBO1,ROPN1,ROPN1L,ROR2,RSPH9,RTN4,S100A12,S100A2,S100A8,S100A9,S100P,S1PR1,SAA1,SAA2,SAA2-SAA4,SAA4,SATB2,SBDS,SBK2,SCARB1,SCG2,SCRIB,SCYL3,SDC2,SDC4,SDCBP,SELE,SELL,SELP,SEMA3A,SEMA3C,SEMA4C,SEMA5A,SEPT12,SETD2,SGPL1,SH3BP1,SH3KBP1,SHC1,SHROOM2,SIRPA,SIRPG,SIX2,SKI,SLA,SLA2,SLC16A1,SLC16A8,SLC22A16,SLC26A8,SLC3A2,SLC7A10,SLC7A11,SLC7A5,SLC7A6,SLC7A7,SLC7A8,SLC7A9,SLC9A1,SLC9B1,SLC9B2,SLIRP,SLIT2,SMCP,SMO,SNAI1,SNAI2,SOCS7,SORD,SOS1,SOX1,SOX10,SOX17,SOX18,SOX8,SPAG16,SPATA13,SPEF1,SPN,SPNS2,SPOCK1,SRC,SRF,SRGAP2,SRGAP2C,SRPX2,SSTR4,STARD13,STRIP2,STYK1,SUN1,SUN2,SYK,SYNE2,T,TAOK2,TBX1,TBX20,TBX5,TDGF1,TEK,TEKT1,TEKT2,TEKT3,TEKT5,TGFB1,TGFB2,TGFBR1,THBD,THBS1,THBS4,TIAM1,TLX3,TMEFF2,TMEM201,TNF,TNFAIP1,TNFRSF10A,TNFRSF10B,TNFRSF10D,TNFRSF11A,TNFRSF12A,TNFSF11,TNFSF12,TNK2,TNN,TNP1,TNP2,TNR,TNS1,TNS3,TOR1A,TPGS1,TREM1,TRIM46,TRPM2,TRPM4,TSPO,TTLL1,TUBB2B,TWIST1,TYRO3,UMOD,USP9X,USP9Y,VANGL2,VAV1,VAV2,VAV3,VCAM1,VEGFA,VEGFC,VHLL,VIL1,VPREB3,WASF2,WDR1,WNT11,WNT5A,WNT7A,WWC1,XCL1,XCL2,YES1,YWHAE,ZAP70,ZFAND5	TetrapodAncestor	147.705
GO.Biological.Process	GO:0030111	regulation.of.Wnt.signaling.pathway	178	5.450717e-152	7.040691e-148	3.955444e-150	1.239249e+0	ABL1,AES,AMER1,AMER2,AMER3,ANKRD10,ANKRD6,APC,APC2,APCDD1,APOE,ARNTL,ASPM,ATP6AP2,ATP6V0C,ATP6V1C2,AXIN2,BAMBI,BARX1,BICC1,BMP2,BTRC,CAPRIN2,CAV1,CBFB,CBY1,CCAR2,CCND1,CDC73,CDH2,CDK14,CHD8,CITED1,COL1A1,CSNK1A1,CSNK1D,CSNK1E,CSNK2A1,CTNND1,CTNND2,CUL3,CXXC4,DAB2,DAB2IP,DACT1,DACT2,DACT3,DAPK3,DCDC2,DDX3X,DEPDC1B,DISC1,DIXDC1,DKK1,DKK2,DKK3,DKK4,DLX5,DRAXIN,DVL1,DVL3,EDA,EGR1,ENSG00000258864,ESR1,FERMT1,FGF10,FGF9,FGFR2,FOXL1,FOXO1,FOXP3,FUZ,FZD5,FZD6,FZD9,GLI3,GPC3,GPRC5B,GRB10,GREM1,GSC,GSK3A,GSKIP,HDAC1,HECW1,HHEX,HIC1,HMGXB4,HNF1B,IFT20,IGFBP2,IGFBP4,IGFBP6,ISL1,ITGA3,JADE1,JUP,KANK1,KLHL12,KREMEN1,KREMEN2,LATS1,LATS2,LEF1,LGR4,LGR5,LGR6,LIMD1,LRP1,LRP4,LRP5,LRP6,LRRK2,MACF1,MAD2L2,MAPK14,MBD2,MCC,MDFI,MESP1,MKS1,MLLT3,NAIP,NFATC1,NFATC4,NFKB1,NKD2,NKX2-5,NLE1,NLK,NOG,NOTCH1,NOTUM,NPHP3,NPHP4,NXN,PFDN5,PIN1,PLPP3,PPP1CA,PRICKLE1,PRKN,PSEN1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTPRO,RAPGEF1,RBMS3,RBPJ,RNF146,RNF213,RNF220,RNF43,ROR2,RPS27A,RSPO1,RSPO2,RSPO3,RSPO4,RUNX1,SCEL,SCYL2,SDHAF2,SENP2,SFRP1,SFRP2,SFRP4,SFRP5,SHISA2,SIAH2,SKI,SMARCA4,SMURF2,SNAI2,SOST,SOSTDC1,SOX10,SOX17,SOX2,SOX4,SOX7,SOX9,SPIN1,SRC,STK4,SULF2,TAX1BP3,TBX18,TCF7L1,TERT,TIAM1,TLE1,TLE2,TLR2,TMEM131L,TMEM237,TMEM64,TNKS,TNKS2,TNN,TRABD2A,TRABD2B,TRPM4,TSC2,TSKU,UBC,UBR5,VANGL2,VPS35,WIF1,WLS,WNT1,WNT10B,WNT11,WNT3,WNT3A,WNT4,WNT5A,WNT7A,WWOX,WWTR1,XIAP,ZBED3,ZNF703,ZNRF3	TetrapodAncestor	147.152
GO.Biological.Process	GO:0001822	kidney.development	179	5.889087e-152	7.606934e-148	4.249684e-150	1.231893e+0	ACAT1,ACE,ACTA2,ACVR2B,ADAMTS1,ADAMTS16,ADIPOQ,AGT,AGTR1,AGTR2,AHI1,AKR1B1,AMER1,ANGPT1,ANGPT2,APH1A,AQP1,AQP11,AQP2,ARG2,ARID5B,ARL3,BAG6,BASP1,BAX,BCL2,BCL2L11,BMP2,BMP4,BMP6,BMP7,BMPER,C1GALT1,C5orf42,CA2,CALB1,CAT,CD24,CD34,CDKN1C,CENPF,CER1,CITED1,COL4A3,COL4A4,CTNNB1,CTSH,DACT2,DCHS1,DCHS2,DCN,DLG1,DLG5,DLL1,EFNB2,EGR1,ENPEP,EPCAM,EPHA4,EPHA7,EYA1,FAT4,FGF1,FGF10,FGF2,FGFR1,FGFR2,FMN1,FOXC1,FOXC2,FOXJ1,FRAS1,FSTL3,GATA3,GCNT3,GCNT4,GDF11,GDNF,GLI2,GLI3,GPC3,GPR4,GREM1,GZF1,HAS2,HES1,HES5,HEYL,HNF1B,HPGD,ID3,IFT20,IQGAP1,ITGA3,ITGA8,JAG1,JMJD6,KCNJ8,KIF26B,KIRREL3,KLF15,KLHL3,LAMA5,LGR4,LHX1,LRP4,LRRK2,MAGI2,MEF2C,MME,MPST,MPV17,MTSS1,MYC,MYO1E,NF1,NIPBL,NKX3-1,NLE1,NOG,NOTCH1,NOTCH3,NPHP3,NPHS1,NPHS2,NRP1,ODC1,OSR1,OVOL1,PAX2,PAX8,PBX1,PCSK5,PDGFB,PDGFRB,PECAM1,PKD1,PKD1L3,PKD2,PKHD1,PLCE1,PODXL,POU3F3,PRKX,PROM1,PROX1,PTCD2,PTCH1,PTPRO,PYGO2,RARA,RARB,RDH10,REN,RET,RGN,ROBO2,RRM2B,SDC4,SEC61A1,SFRP1,SGPL1,SIM1,SIX2,SLC34A1,SLIT2,SMAD2,SMAD4,SMAD5,SMAD7,SMO,SOX11,SOX4,SOX8,SOX9,SPRY1,STAT1,STRA6,SULF2,TACSTD2,TCF21,TEK,TFAP2A,TFAP2B,TGFB1,TGFB2,TGFBR1,TIPARP,TMED10,TNS2,TP73,TRAF3IP1,UMOD,UPK3A,VANGL2,VEGFA,WFS1,WNK4,WNT1,WNT11,WNT4,WNT6,WNT7B,WNT9B,WWTR1,ZBTB16,ZNF354A	TetrapodAncestor	147.119
GO.Biological.Process	GO:0043062	extracellular.structure.organization	180	8.720974e-152	1.126488e-147	6.258268e-150	1.271616e+0	A2M,ABI3BP,ACAN,ADAM15,ADAM19,ADAM8,ADAMTS14,ADAMTS2,ADAMTS20,ADAMTS3,ADAMTS4,ADAMTS5,ADAMTS9,ADAMTSL2,AGRN,APBB2,APP,ATXN1L,B4GALT1,BCAN,BCL3,BGN,BMP1,BSG,CAPN1,CAPN2,CCDC80,CD44,CD47,CDH1,COL10A1,COL11A1,COL12A1,COL13A1,COL14A1,COL16A1,COL18A1,COL1A1,COL1A2,COL27A1,COL2A1,COL3A1,COL4A3,COL4A4,COL4A5,COL4A6,COL5A1,COL5A2,COL5A3,COL6A1,COL6A2,COL6A3,COL7A1,COL8A1,COL8A2,COL9A2,COL9A3,CREB3L1,CRISPLD2,CSGALNACT1,CTGF,CTRB1,CTRB2,CTSL,CYP1B1,CYR61,DCN,DDR1,DDR2,DMP1,DNAJB6,DPT,DSPP,ECM2,EFEMP2,EGFLAM,ELF3,ELN,ENG,ERCC2,ERO1A,ERO1B,EXOC8,F11R,FBLN1,FBLN5,FBN2,FERMT1,FGF2,FGG,FLOT1,FLRT2,FMOD,FN1,FOXC1,FOXC2,FOXF1,FOXF2,FURIN,GAS6,GFAP,GFOD2,GPM6B,GREM1,HAPLN1,HAPLN2,HAS2,HAS3,HPN,HPSE2,HSD17B12,HSPG2,HTRA1,IBSP,ICAM2,IHH,ITGA1,ITGA10,ITGA11,ITGA2,ITGA2B,ITGA3,ITGA4,ITGA5,ITGA7,ITGA8,ITGA9,ITGAD,ITGAE,ITGAM,ITGAV,ITGAX,ITGB1,ITGB2,ITGB4,ITGB5,ITGB7,ITGB8,JAM2,JAM3,KAZALD1,KIF9,KLKB1,LAMA1,LAMA2,LAMA3,LAMA4,LAMA5,LAMB1,LAMB3,LAMC3,LCP1,LOX,LOXL1,LOXL2,LOXL3,LUM,MADCAM1,MATN1,MATN3,MATN4,MFAP2,MFAP5,MMP1,MMP10,MMP11,MMP12,MMP13,MMP14,MMP15,MMP16,MMP19,MMP20,MMP3,MMP7,MMP8,MMP9,MPV17,MPZL3,MYO1E,NDNF,NF1,NFKB2,NID2,NOXO1,NPHS1,OPTC,P3H4,P4HA1,PDGFA,PDGFB,PECAM1,PLG,POMT1,PRDX4,PRSS1,PRSS2,PTK2,PXDN,RAMP2,RECK,RIC8A,SCUBE1,SCX,SERAC1,SERPINB5,SERPINH1,SFRP2,SH3PXD2A,SMOC2,SOX9,SPINK5,SPINT1,SPOCK2,SPP1,SULF2,TEX14,TGFB1,TGFB2,TGFBI,TGFBR1,THBS1,THSD4,TIMP1,TIMP2,TLL1,TLL2,TMPRSS6,TNC,TNF,TNFRSF11B,TNR,TNXB,TPSAB1,TTR,VCAM1,VCAN,VHLL,VIPAS39,VIT,VPS33B,VTN,VWA1,VWF,WNT3A	TetrapodAncestor	146.948
GO.Biological.Process	GO:0030198	extracellular.matrix.organization	181	9.369260e-152	1.210227e-147	6.686339e-150	1.271596e+0	A2M,ABI3BP,ACAN,ADAM15,ADAM19,ADAM8,ADAMTS14,ADAMTS2,ADAMTS20,ADAMTS3,ADAMTS4,ADAMTS5,ADAMTS9,ADAMTSL2,AGRN,APBB2,APP,ATXN1L,B4GALT1,BCAN,BCL3,BGN,BMP1,BSG,CAPN1,CAPN2,CCDC80,CD44,CD47,CDH1,COL10A1,COL11A1,COL12A1,COL13A1,COL14A1,COL16A1,COL18A1,COL1A1,COL1A2,COL27A1,COL2A1,COL3A1,COL4A3,COL4A4,COL4A5,COL4A6,COL5A1,COL5A2,COL5A3,COL6A1,COL6A2,COL6A3,COL7A1,COL8A1,COL8A2,COL9A2,COL9A3,CREB3L1,CRISPLD2,CSGALNACT1,CTGF,CTRB1,CTRB2,CTSL,CYP1B1,CYR61,DCN,DDR1,DDR2,DMP1,DNAJB6,DPT,DSPP,ECM2,EFEMP2,EGFLAM,ELF3,ELN,ENG,ERCC2,ERO1A,ERO1B,EXOC8,F11R,FBLN1,FBLN5,FBN2,FERMT1,FGF2,FGG,FLOT1,FLRT2,FMOD,FN1,FOXC1,FOXC2,FOXF1,FOXF2,FURIN,GAS6,GFAP,GFOD2,GPM6B,GREM1,HAPLN1,HAPLN2,HAS2,HAS3,HPN,HPSE2,HSD17B12,HSPG2,HTRA1,IBSP,ICAM2,IHH,ITGA1,ITGA10,ITGA11,ITGA2,ITGA2B,ITGA3,ITGA4,ITGA5,ITGA7,ITGA8,ITGA9,ITGAD,ITGAE,ITGAM,ITGAV,ITGAX,ITGB1,ITGB2,ITGB4,ITGB5,ITGB7,ITGB8,JAM2,JAM3,KAZALD1,KIF9,KLKB1,LAMA1,LAMA2,LAMA3,LAMA4,LAMA5,LAMB1,LAMB3,LAMC3,LCP1,LOX,LOXL1,LOXL2,LOXL3,LUM,MADCAM1,MATN1,MATN3,MATN4,MFAP2,MFAP5,MMP1,MMP10,MMP11,MMP12,MMP13,MMP14,MMP15,MMP16,MMP19,MMP20,MMP3,MMP7,MMP8,MMP9,MPV17,MPZL3,MYO1E,NDNF,NF1,NFKB2,NID2,NOXO1,NPHS1,OPTC,P3H4,P4HA1,PDGFA,PDGFB,PECAM1,PLG,POMT1,PRDX4,PRSS1,PRSS2,PTK2,PXDN,RAMP2,RECK,RIC8A,SCUBE1,SCX,SERAC1,SERPINB5,SERPINH1,SFRP2,SH3PXD2A,SMOC2,SOX9,SPINK5,SPINT1,SPOCK2,SPP1,SULF2,TGFB1,TGFB2,TGFBI,TGFBR1,THBS1,THSD4,TIMP1,TIMP2,TLL1,TLL2,TMPRSS6,TNC,TNF,TNFRSF11B,TNR,TNXB,TPSAB1,TTR,VCAM1,VCAN,VHLL,VIPAS39,VIT,VPS33B,VTN,VWA1,VWF,WNT3A	TetrapodAncestor	146.917
GO.Biological.Process	GO:0010638	positive.regulation.of.organelle.organization	182	2.925935e-151	3.779430e-147	2.076610e-149	1.215193e+0	ABI2,ABL1,ABLIM3,ACD,ACSM6,ACTR2,ACTR3,ACTR3B,ACTR3C,ADRB2,AKT2,ALOX15,ANAPC11,ANK1,ANKRD53,ANXA1,APOA1,ARF6,ARHGAP35,ARL2,ARPC1A,ARPC1B,ARPC2,ARPC4,ARPC4-TTLL3,ARPC5,ASAP1,ATG13,ATL3,ATM,ATMIN,ATPIF1,ATR,AURKA,AURKB,BAD,BAG4,BAIAP2L2,BAK1,BAP1,BAX,BBS4,BCAS3,BCL2,BCL2L11,BECN1,BID,BIK,BMP10,BNIP3,BRAF,BTC,C15orf62,C1QBP,C2CD5,CAMKK2,CARMIL1,CARMIL2,CASP8,CAV3,CCDC88A,CCL11,CCL21,CCP110,CCR7,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,CD28,CDC42,CDC42EP1,CDC42EP2,CDC42EP3,CDC42EP4,CDC42EP5,CDCA5,CDK5,CDK5RAP1,CDKL2,CDKN1B,CEP120,CEP295,CFL1,CFL2,CIDEB,CLASP1,CLEC16A,CNOT1,CNOT2,CNOT6,CNOT6L,COA3,CROCC,CSF3,CSNK2A2,CTGF,CTNNB1,CTTN,CUL3,CYB5R1,CYFIP1,DAZL,DCN,DCTN1,DDHD1,DDHD2,DDX11,DKC1,DLG1,DLGAP5,DMRT1,DNM1L,DOC2B,DRD3,DSTN,DTWD2,DYNLL1,DYNLL2,E2F1,EDN1,EDN3,EGF,ELMOD1,ENSG00000284292,EPGN,EPHA1,ERCC1,EREG,ESPL1,EVL,F2RL1,FAM162A,FAM20B,FBXO4,FBXO7,FBXW7,FEN1,FER,FES,FHOD1,FIS1,FMN1,FSCN1,FUZ,FYCO1,FZD5,GBA,GNL3,GPER1,GPHA2,GPR65,GRB2,GSK3A,GSN,H2AFY,HAP1,HAX1,HCK,HCLS1,HES1,HHAT,HIF1A,HIP1R,HMBOX1,HNMT,HNRNPA2B1,HNRNPD,HNRNPU,HPS4,HRAS,HRK,HTRA2,HTT,ID1,IFNL3,IGF1,IGF2,IL1A,IL1B,IL5,INS,IRGM,ITGAX,JMY,KATNB1,KATNBL1,KCNN3,KCTD17,KIAA1324,KIF5B,KIRREL1,LCP1,LEPROT,LIG4,LIMK1,LMAN1,LMOD1,LMOD3,LPAR1,LRP5,LRSAM1,MAP2K7,MAP3K4,MAPK1,MAPK15,MAPK3,MAPK8,MAPK9,MAPKAPK5,MAPT,MARCH5,MECP2,MET,MFF,MGARP,MIEF1,MIEF2,MIS18A,MLLT11,MLST8,MMP9,MRE11,MRGPRE,MRPS27,MSN,MSX1,MSX2,MTOR,MUL1,MYBPC1,MYLK3,MYO1C,NAF1,NAV3,NBN,NCK1,NCK2,NCKAP1,NCKAP1L,NEK7,NES,NEUROG1,NF2,NMT1,NMUR1,NOX4,NPEPPS,NPHS1,NPM1,NPM2,NRG1,NRP1,NSMCE2,NSUN4,NTF3,NTRK3,NUP62,NUSAP1,OPA1,P2RX7,PAK1,PAN3,PARK7,PARN,PDCD5,PDCD6IP,PDGFB,PDGFRB,PDXP,PEMT,PFDN2,PFN1,PFN2,PFN3,PHIP,PINK1,PIP4K2A,PIP4K2B,PIP4K2C,PIWIL2,PKIB,PLA2G6,PLCB1,PLD6,PLEK,PLK4,PLXNA3,PMAIP1,PML,PNKP,POC1A,POLR3A,POT1,PPARGC1A,PPIF,PPM1E,PPM1F,PPP1R13B,PPP3CC,PPP3R1,PRDM9,PRELID3A,PRKCE,PRKCQ,PRKN,PROX1,PSMB7,PSMD8,PTK2B,PXN,PYCARD,RAB3GAP1,RAB3GAP2,RAC1,RAC2,RAD21,RAD50,RALB,RANBP2,RANBP3,RANBP3L,RAPGEF3,RB1,RGCC,RGPD4,RGS2,RHOU,RICTOR,RNF31,ROCK2,RP1,RPL28,RPS3,RUVBL1,S100A10,SAXO1,SCIN,SDC4,SDCBP,SELENOI,SEMA5A,SEPT7,SEPT9,SFN,SFPQ,SFRP1,SH2B1,SH3GLB1,SHCBP1L,SIRT2,SIRT6,SLAIN2,SLF1,SLF2,SLX1A,SLX1B,SLX4,SMC5,SMCR8,SNIP1,SORBS3,SPIRE1,SPIRE2,SRC,SREBF2,STAP1,STARD7,STMN2,STX18,SURF4,SYNJ1,SYNPO,SYT1,TAC1,TAPT1,TCP1,TDRD12,TEK,TENM1,TFDP2,TGFB1,TGFBR1,TMED9,TMEM27,TNF,TNFSF10,TNKS,TNKS2,TOGARAM1,TOMM7,TP53,TP53BP2,TP63,TP73,TPR,TRMT10C,TSG101,TSGA13,U2AF1,U2AF2,UBE2C,UBE2D3,UBE2J2,UBE2L3,UBL5,UGCG,UQCC1,UQCC2,USP36,UVRAG,VASP,VIL1,VPS11,VPS35,VPS37B,VPS4A,VPS4B,WASHC2C,WBP11,WDR1,WDR35,WDR46,WDR75,WNT11,WNT4,WNT5A,XRCC5,YWHAB,YWHAE,YWHAG,YWHAH,YWHAZ,ZBED3,ZBTB17,ZDHHC8,ZNF205	TetrapodAncestor	146.423
GO.Biological.Process	GO:0050730	regulation.of.peptidyl-tyrosine.phosphorylation	183	1.809943e-150	2.337903e-146	1.277543e-148	1.299654e+0	ABI1,ABL1,ACE,ADIPOQ,ADNP,ADORA1,ADRA2A,ADRA2B,ADRA2C,AFAP1L2,AGT,ALKAL1,ANGPT1,ANGPT4,APP,AREG,ARHGEF2,ARL2BP,ARRB2,BANK1,BST1,CAV1,CBL,CBLB,CBLC,CCK,CCL5,CD24,CD300A,CD36,CD3E,CD40,CD44,CD74,CD80,CD81,CHMP6,CLCF1,CNTF,CNTN1,CSF1R,CSF3,CSPG4,CTF1,DGKQ,DMTN,EFNA1,EFNA5,EGF,EGFR,EHD4,ENPP2,EPGN,EPHA4,EPHA7,EPO,ERBB4,ERCC6,EREG,ERRFI1,FBXW7,FGF10,FGF7,FGFR1OP,FGFR3,GAS6,GGNBP2,GH1,GHR,GPRC5A,GPRC5B,GREM1,GRM5,HAX1,HBEGF,HCLS1,HDAC2,HES1,HES5,HGF,HRG,HSF1,HSPH1,HTR2A,IBTK,IFNA2,IFNAR1,IFNG,IFNL1,IGF1,IGF2,IL12A,IL12B,IL13,IL15,IL18,IL2,IL20,IL21,IL22RA2,IL23A,IL23R,IL24,IL31RA,IL4,IL5,IL6,IL6R,IL6ST,INS,IQGAP1,ISL1,ITGA5,ITGB2,JAK2,KITLG,LACRT,LEP,LIF,LRP4,LRP8,LYN,MIF,MLST8,MTOR,MVP,NCF1,NCK2,NEURL1,NF2,NRG1,NRP1,NTF3,OSM,PAK2,PARP14,PARP9,PDCL3,PDGFA,PDGFB,PDGFC,PDGFD,PPP2R5B,PRKCD,PRKCE,PRKCZ,PSEN1,PTK2B,PTPN1,RAP2B,RAP2C,RELN,RICTOR,RIPK2,SAMSN1,SEMA4D,SFRP1,SFRP2,SH3BP5,SHC1,SNX6,SOCS1,SOCS3,SOCS4,SOCS5,SPINK1,SRC,SRCIN1,STAP1,STAP2,SYK,TDGF1,TEC,TGFB1,THBS4,THY1,TNFRSF14,TNFRSF18,TNFRSF1A,TNFSF18,TNK2,TP53,TREM2,TSG101,UNC119,VEGFA,VEGFC,VPS25,VTN,WNT3A,YES1,ZFYVE28	TetrapodAncestor	145.631
GO.Biological.Process	GO:0002761	regulation.of.myeloid.leukocyte.differentiation	184	2.124641e-150	2.744399e-146	1.491521e-148	1.423509e+0	ACIN1,ADIPOQ,ATP6AP1,BGLAP,C1QC,CA2,CAMK4,CARTPT,CASP8,CCL3,CCR1,CD101,CD74,CDK6,CEBPB,CLDN18,CREB1,CSF1,CTNNB1,CUL4A,ESRRA,FADD,FOS,FSHB,FSHR,FSTL3,GATA2,GNAS,GPR55,GPR68,HAX1,HCLS1,IFNG,IL12B,IL17A,IL20,IL23A,IL23R,IL34,IL4,IL5,INHA,INHBA,INPP5D,IRF7,JUN,KITLG,KLF10,LEF1,LHCGR,LIF,LILRB4,LRRC17,LYN,MAFB,MTOR,MYC,NDFIP1,NF1,NME1,NME2,OCSTAMP,PF4,PIK3R1,POU4F1,PPARGC1B,PRKCA,RARA,RASSF2,RB1,RIPK1,ROR2,RUNX1,SFRP1,SIGLEC15,SLC9B2,TAL1,TESC,TFE3,TJP2,TLR3,TLR4,TMEM178A,TMEM64,TNF,TNFSF11,TRAF6,TRIB1,UBASH3B,ZFP36L1,ZFPM1,ZNF675	TetrapodAncestor	145.562
GO.Biological.Process	GO:0045087	innate.immune.response	185	2.457022e-150	3.173735e-146	1.715533e-148	1.249800e+0	ABL1,ABL2,ADAM15,ADAMTS13,ADAR,ADARB1,ADGRB1,AGER,AIF1,AKAP8,AKIRIN2,ANKHD1,ANKHD1-EIF4EBP3,ANKRD17,ANXA1,APOA4,APOBEC3A,APOBEC3B,APOBEC3C,APOBEC3D,APOBEC3F,APOBEC3G,APOBEC3H,APOL1,APP,AQP4,ARG1,ARG2,ARHGEF2,ARID5A,ATG12,ATG5,AXL,BCL10,BLK,BMX,BPIFA1,BPIFB1,BPIFB3,BST2,BTK,C19orf66,C1QA,C1QB,C1QBP,C1QC,C3,C4A,C4B,C4BPA,C4BPB,C5,C6,C7,C8A,C8B,C8G,C9,CACTIN,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CAPZA2,CASP1,CASP4,CCL1,CCL11,CCL13,CCL14,CCL15,CCL15-CCL14,CCL16,CCL17,CCL18,CCL19,CCL2,CCL21,CCL22,CCL23,CCL3,CCL3L3,CCL4,CCL4L2,CCL5,CCL7,CCL8,CD14,CD180,CD1D,CD209,CD300E,CD300LB,CD40,CD44,CD46,CD55,CD58,CD6,CD86,CEBPG,CFH,CFHR5,CFI,CFP,CHGA,CHID1,CHUK,CIITA,CITED1,CLDN1,CLEC2A,CLEC4A,CLEC4C,CLEC4D,CLEC4E,CLEC4M,CLEC6A,CLEC7A,CLU,CNPY3,COLEC10,COLEC11,COLEC12,CORO1A,CR1,CR2,CRCP,CRISP3,CSF1,CSF1R,CSK,CX3CL1,CXCL16,CYBA,CYBB,CYP27B1,DAB2IP,DAPK1,DAPK3,DCST1,DDX3X,DDX58,DDX60,DEFB110,DEFB112,DEFB113,DEFB115,DEFB124,DEFB131A,DEFB133,DHX9,DMBT1,ECSIT,EDN1,EGR1,EIF2AK2,ELF4,ENSG00000173366,EPRS,F12,F2RL1,FADD,FCER1G,FCN1,FCN2,FCN3,FER,FES,FGR,FRK,GAPDH,GATA3,GCH1,GPER1,GRAP,GRAP2,GRB2,GSDMD,GZMM,H2BFS,HAVCR2,HCK,HEXIM1,HIST2H2BE,HMGB1,HMGB2,HMGB3,IFI27,IFI35,IFI6,IFIT1,IFIT2,IFIT3,IFIT5,IFITM1,IFITM2,IFITM3,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNAR1,IFNAR2,IFNB1,IFNE,IFNG,IFNGR1,IFNGR2,IFNL1,IFNL2,IFNL3,IFNLR1,IFNW1,IGLL1,IGLL5,IKBKB,IKBKE,IKBKG,IL12B,IL12RB1,IL18,IL1RAP,IL1RL2,IL23A,IL23R,IL27,IL34,IL36A,IL36B,IL36G,IL36RN,IL4,INAVA,IRAK1,IRAK4,IRF1,IRF2,IRF3,IRF4,IRF6,IRF7,IRF8,IRF9,IRGM,ISG15,ISG20,ITCH,ITK,JAK2,JAK3,JCHAIN,KLRC2,KLRD1,KLRF2,KLRG1,KLRK1,KRT1,KRT16,KYNU,LBP,LCK,LCN2,LGALS3,LGALS9,LGR4,LILRA4,LILRA5,LY86,LY96,LYN,MALT1,MAP3K5,MARCO,MASP1,MASP2,MATK,MATR3,MB21D1,MBL2,MCOLN2,MEFV,MID1,MID2,MIF,MR1,MRC1,MST1R,MX1,MX2,NAIP,NCAM1,NCF1,NCF2,NCR2,NFKB1,NFKB2,NLRC4,NLRC5,NLRP1,NLRP10,NLRP2,NLRP6,NLRP9,NLRX1,NMI,NOD1,NOS2,NR1H4,NRROS,NUB1,OAS1,OASL,OPTN,OTULIN,PADI4,PCBP2,PDE12,PGLYRP1,PGLYRP2,PGLYRP3,PGLYRP4,PIK3CA,PIK3CD,PIK3CG,PLA2G1B,PML,POLR3A,POLR3B,POLR3C,POLR3D,POLR3E,POLR3F,POLR3K,PPARG,PPP1R14B,PQBP1,PRDM1,PRDX1,PRKCD,PRKD1,PRKDC,PSPC1,PSTPIP1,PTAFR,PTK2,PTK2B,PTX3,PYCARD,PYDC1,PYDC2,RAB27A,RAET1E,RAET1G,RAET1L,RARRES2,RBM14,REL,RELB,RIOK3,RIPK2,RNASEL,RNF135,RPL13A,RPS27A,RSAD2,S100A12,S100A7,S100A8,S100A9,S100B,SAA1,SAMHD1,SARM1,SDHAF4,SEC14L1,SEC61A1,SERINC3,SERINC5,SERPING1,SETD2,SFPQ,SH2D1A,SH2D1B,SHMT2,SIGLEC15,SIRPB1,SIRT2,SLA,SLA2,SLAMF6,SLC11A1,SLC30A8,SLPI,SMPDL3B,SNCA,SP100,SPON2,SRC,SRPK1,SRPK2,SSC5D,STAR,STAT1,STAT2,STYK1,SUSD4,SYK,SYNCRIP,TARM1,TBK1,TBKBP1,TDGF1,TEC,TGFB1,TICAM1,TICAM2,TIRAP,TKFC,TLR1,TLR10,TLR2,TLR3,TLR4,TLR5,TLR6,TLR9,TMEM173,TNFAIP8L2,TNK2,TOLLIP,TRAF3,TREM1,TREM2,TREML1,TREML4,TRIL,TRIM11,TRIM13,TRIM21,TRIM22,TRIM25,TRIM28,TRIM32,TRIM34,TRIM35,TRIM38,TRIM5,TRIM62,TRIM68,TRIM8,TUBB,TUBB4B,UBC,ULBP1,ULBP2,ULBP3,UNC93B1,VCAM1,VNN1,VSIG4,WNT5A,XAF1,XCL1,XCL2,XRCC5,XRCC6,YES1,ZAP70,ZBP1,ZBTB1,ZC3HAV1,ZNF683	TetrapodAncestor	145.498
GO.Biological.Process	GO:0032102	negative.regulation.of.response.to.external.stimulus	186	4.265206e-150	5.509367e-146	2.962025e-148	1.279872e+0	ABAT,ABCC8,ABR,ACP5,ADA,ADAMTS18,ADCYAP1,ADIPOQ,ADORA1,ADORA2A,AGER,AIF1,AJAP1,ANGPT2,APOA1,APOD,APOE,APOH,ARG2,ASH1L,BBS4,BCR,C1QBP,C1QTNF1,C1QTNF12,C1QTNF3,C5,C5orf30,CACTIN,CALCRL,CARD16,CARTPT,CASK,CCK,CCL2,CD109,CD34,CD9,CERS2,CHID1,CLASP1,CLASP2,CNR2,CORO1B,CPB2,CRK,CTNNA2,CX3CR1,CXCL13,CYP19A1,DDT,DRD1,DRD2,DRD3,DUSP10,DVL1,EDN1,EIF2AK2,EPHA4,ETS1,F11,F12,F2,FABP7,FAM3A,FEM1A,FFAR4,FGF2,FGG,FNDC4,FOXF1,FOXP3,GATA3,GBA,GHSR,GJA1,GP1BA,GPATCH3,GPER1,GPR17,GPR18,GREM1,GRID2,GRIN1,GRIN3A,GSTP1,HAVCR2,HGF,HMGCR,HRG,HTRA1,IFIT1,IL10,IL12B,IL1R2,IL2,IL20RB,IL22RA2,IL4,INS,ISL1,ITCH,KANK2,KLF4,KLKB1,KLRK1,KNG1,KRT1,LACRT,LEP,LRIG2,MEFV,METRNL,MIF,MKKS,MMP26,MMP28,MUL1,NBL1,NDFIP1,NENF,NFKB1,NLRC3,NLRP6,NLRP7,NLRX1,NOS3,NOTCH1,NOV,NPFF,NPY5R,NR1H3,NR1H4,NRP1,NRXN1,NT5E,OTULIN,PADI2,PBK,PCBP2,PDGFA,PDGFB,PGLYRP1,PHLDB2,PLAT,PLAU,PLG,PLXNA3,PPARA,PPARD,PPARG,PRDM1,PRKCD,PRKG1,PROC,PROS1,PROZ,PSMB4,PTEN,PTGER4,PTGIS,PTPRO,PTPRS,PYDC2,RGMA,RIOK3,RNF125,RNF26,ROBO1,ROBO2,RTN4R,SAA1,SCRIB,SEC14L1,SEMA3A,SEMA5A,SERPINB2,SERPINE2,SERPING1,SHARPIN,SIGIRR,SIRT2,SLC6A3,SLIT2,SMPDL3B,SNAI2,SOCS3,SOCS5,SPINK5,SPN,SPP1,SPX,STAP1,TARBP2,TEK,THBD,THBS1,TKFC,TMPRSS6,TNFAIP3,TNFAIP6,TNFAIP8L2,TNFRSF1A,TNFRSF1B,TNR,TRAF3IP1,TRIB1,TSPAN6,TSPAN8,TYRO3,UBASH3B,UCN,UFD1,VPS35,VTN,WFDC1,WNT3,WNT3A,WNT4,WNT5A,ZC3H12A	TetrapodAncestor	145.259
GO.Biological.Process	GO:0002253	activation.of.immune.response	187	5.630333e-150	7.272701e-146	3.889145e-148	1.259266e+0	ABI1,ABL1,ACTR2,ACTR3,APOB,ARPC1A,ARPC1B,ARPC2,ARPC4,ARPC5,BAG6,BAX,BCAR1,BCL10,BCL2,BIRC2,BIRC3,BLK,BRAF,BTK,BTRC,C1QA,C1QB,C1QBP,C1QC,C3,C3AR1,C4A,C4B,C4BPA,C4BPB,C5,C6,C7,C8A,C8B,C8G,C9,CARD11,CASP8,CD14,CD180,CD19,CD209,CD247,CD28,CD300LF,CD36,CD38,CD3D,CD3E,CD3G,CD46,CD55,CD79B,CD86,CDC42,CFH,CFHR1,CFHR5,CFI,CFP,CHUK,CLEC4A,CLEC4C,CLEC4D,CLEC4E,CLEC6A,CLEC7A,CLU,CNPY3,COLEC10,COLEC11,COLEC12,CR1,CR2,CRK,CSK,CTLA4,CTSB,CTSL,CUL1,CYFIP1,CYFIP2,DDX58,DENND1B,DMBT1,ELMO1,ELMO2,ENSG00000173366,EP300,FADD,FBXW11,FCER1G,FCN1,FCN2,FCN3,FFAR2,FGG,FGR,FOXP3,FYB1,FYB2,GATA3,GPLD1,GPR32,GPR33,GRAP2,GRB2,HAVCR2,HCK,HEXIM1,HMGB1,HMSD,HRAS,HSP90AB1,HSP90B1,ICAM2,IFNG,IGLL1,IGLL5,IKBKB,IKBKE,IKBKG,INAVA,INPP5D,IRAK1,IRAK3,IRAK4,IRF3,IRF7,IRGM,ITCH,ITGAM,ITGB2,ITK,KLHL6,KLRK1,KRAS,KRT1,LAT,LAT2,LAX1,LBP,LCK,LCP2,LGMN,LIMK1,LRRC70,LY96,LYN,MALT1,MAP2K6,MAP3K1,MAP3K7,MAPK1,MAPK3,MAPKAPK2,MAPKAPK3,MARCO,MASP1,MASP2,MATR3,MB21D1,MBL2,MEF2C,MUC1,MUC12,MUC13,MUC15,MUC20,MUC3A,MUC4,MUC5AC,MUC5B,MUC6,MUCL1,MYO10,MYO1C,MYO1G,NCK1,NCKAP1,NCKAP1L,NCR3,NFAM1,NFATC2,NFKB1,NLRC4,NOD1,NR1H4,NR4A3,NRAS,OTULIN,PAG1,PAK1,PAK2,PAK3,PDE4B,PDE4D,PDPK1,PGLYRP1,PGLYRP2,PGLYRP3,PGLYRP4,PIK3AP1,PIK3C3,PIK3CA,PIK3CD,PIK3R1,PIK3R2,PLA2G6,PLCG1,PLCG2,PLD2,PLEKHA1,PLPP4,PQBP1,PRKACA,PRKACG,PRKCB,PRKCD,PRKCE,PRKCQ,PRKD2,PRKDC,PSEN1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PSPC1,PTK2,PTPN22,PTPRJ,PYCARD,RAC1,RAF1,RBCK1,RBM14,REG3G,RELA,RELB,RFTN1,RFTN2,RGCC,RIPK1,RIPK2,RNF31,RPS27A,RPS6KA3,RPS6KA5,S100A1,S100A14,S100A8,S100A9,SERPING1,SFPQ,SHB,SKAP2,SLA2,SNAI3,SPG21,SPPL3,SRC,SUSD4,SYK,TAB1,TAB2,TAB3,TBK1,TEC,THEMIS,THEMIS2,THY1,TICAM1,TICAM2,TIRAP,TLR1,TLR10,TLR2,TLR3,TLR4,TLR5,TLR6,TLR9,TMEM173,TMEM189-UBE2V1,TNFAIP3,TNFRSF21,TNIP1,TNIP2,TNIP3,TRAF3,TRAF6,TRAT1,TRIL,TRIM5,TXK,UBC,UBE2D1,UBE2D2,UBE2D3,UBE2N,UNC93B1,VAV1,VAV2,VAV3,VSIG4,WASF2,WIPF2,WIPF3,XRCC5,XRCC6,YES1,ZAP70	TetrapodAncestor	145.138
GO.Biological.Process	GO:2000377	regulation.of.reactive.oxygen.species.metabolic.process	188	8.010264e-150	1.034686e-145	5.503648e-148	1.416712e+0	AATF,ACE2,ACP5,ADGRB1,AGT,AGTR1,AGTR2,AGXT2,AIF1,ARF4,ARG2,ASS1,ATG5,ATP2B4,BCL2,BCO2,BCR,BECN1,BIRC2,BMP7,BNIP3,BRCA1,BST1,CAV1,CD34,CD36,CDKN1A,CFLAR,CLU,CRYAB,CTNS,CYBA,CYP1B1,DDAH1,DHFR,DNM2,DUOXA1,EDN1,EGFR,EIF6,F2,F2RL1,FBLN5,FOXM1,FOXO1,G6PD,GADD45A,GCH1,GLA,GRB2,GRIN1,GSTP1,HBB,HDAC4,HIF1A,HP,HSP90AB1,IFNG,IL10,IL1B,IL4,IL6,INS,ITGAM,ITGB2,JAK2,KHSRP,KLF2,KLF4,KLRK1,LEP,MAPK14,MAPT,MMP3,MPV17,MPV17L,MTOR,MYCN,NOS1AP,NOX4,NOXO1,NQO2,P2RX4,PARK7,PARL,PAX2,PDGFB,PDGFRB,PDK3,PID1,PINK1,PKD2,PLIN5,PRCP,PRKCD,PRKN,PTGIS,PTK2B,PTX3,RAB27A,RAC1,RAC2,RGN,RIPK1,RIPK3,RNF41,ROMO1,SIRT2,SIRT3,SIRT5,SLC25A33,SLC30A10,SNCA,SOD1,STK17A,SYK,SZT2,TFAP2A,TGFB1,TGFBR2,THBS1,TICAM1,TIGAR,TLR4,TLR5,TLR6,TNF,TP53,TRAP1,TRPV1,TSPO,UCP1,WDR35,XDH,ZC3H12A,ZNF205	TetrapodAncestor	144.985
GO.Biological.Process	GO:0009790	embryo.development	189	1.819255e-148	2.349932e-144	1.243350e-146	1.131050e+0	AATF,ABI1,ABL1,ABR,ACD,ACSL4,ACVR1B,ACVR2A,ACVR2B,ACVRL1,ADA,ADAR,ADD1,AFF3,AHI1,AKIRIN2,ALDH1A3,ALKBH1,ALS2,ALX1,ALX4,AMBRA1,AMOT,ANGPT1,APAF1,APBA1,APBA2,APBA3,APELA,APLNR,APOB,AR,ARHGAP35,ARID1A,ARID2,ARL13B,ARNT2,ASCL2,ATM,ATOH1,ATOH8,ATP5A1,ATP6AP2,ATP6V1B1,ATP8A2,AXIN2,B9D1,BAG6,BASP1,BAX,BBS4,BBS7,BCL10,BCL2L1,BCL2L11,BCR,BIRC6,BMP2,BMP4,BMP5,BMP7,BMPR1A,BMPR2,BRCA1,BYSL,C2CD3,C2orf49,C5,C5orf42,C6,CACNA1C,CAMSAP3,CAPN2,CASP8,CCDC103,CCDC40,CCM2,CCNB1,CCNB1IP1,CDC73,CDK5R1,CDKN1C,CDON,CEBPA,CEBPB,CECR2,CELF1,CELF4,CELSR1,CENPU,CER1,CFL1,CHD7,CHD8,CHRD,CHRNA10,CHRNA9,CHST11,CITED1,CITED2,CLIC5,CNOT2,CNOT3,COBL,COL11A1,COL12A1,COL1A1,COL2A1,COL6A1,COL7A1,COL8A1,COPS3,CRABP2,CRB2,CTNNB1,CUL3,CUL4A,CXCL8,CXXC4,CYP26B1,CYR61,DACT1,DAD1,DCANP1,DCHS1,DEAF1,DISP1,DKK1,DLC1,DLD,DLG1,DLL1,DLL3,DLL4,DLX5,DNAAF1,DNAJB6,DNMT3A,DPPA3,DSCAML1,DUSP1,DUSP2,DUSP3,DVL1,DVL3,DYNC2H1,E2F7,E2F8,EDN1,EFEMP1,EFNA1,EFNB1,EGF,EGFR,EGLN1,EIF2S2,EIF4A3,EIF4E2,ELF3,ELF5,EMX1,EN1,ENDOG,ENG,EOMES,EP300,EPAS1,EPB41L5,EPHA2,EPHB2,EPN1,ERBB4,ERCC1,ERCC2,ERCC3,ETNK2,ETS2,EXOC4,EXT1,EXT2,EYA1,EYA2,FAM212A,FBN2,FBXW8,FERD3L,FGF10,FGF2,FGF4,FGF9,FGFR1,FGFR2,FLCN,FLRT3,FLT1,FLT3LG,FLVCR1,FN1,FOSL1,FOXA1,FOXA2,FOXC1,FOXC2,FOXE1,FOXF1,FOXF2,FOXG1,FOXH1,FOXI1,FOXN4,FRAS1,FRS2,FUT10,FUT8,FUZ,FXN,FZD1,FZD2,FZD3,FZD5,FZD6,GABPA,GATA2,GATA3,GATA4,GATA6,GBX2,GCM2,GDF3,GDF5,GDNF,GGNBP2,GINS1,GINS4,GJB3,GJB5,GLI2,GLI3,GNA12,GNA13,GNAQ,GNAS,GPC3,GRB2,GREM1,GREM2,GRHL2,GRHL3,GRSF1,GSC,HAND1,HAND2,HDAC1,HDAC2,HEG1,HES1,HES3,HES5,HES7,HESX1,HEY1,HEY2,HHEX,HIF1A,HINFP,HIPK1,HIPK2,HIRA,HLX,HMGA2,HNF1B,HOXA1,HPN,HS6ST1,HSBP1,HSD17B2,HSF1,HTR2B,HUS1,ID2,ID3,IFITM5,IFT140,IFT172,IFT52,IFT57,IGF2,IHH,IL10,IMPAD1,INHBA,INPP5B,INPP5K,INSIG2,INTU,ISL1,ITGA2,ITGA3,ITGA4,ITGA5,ITGA7,ITGA8,ITGAV,ITGB1,ITGB2,ITGB4,ITGB5,ITPK1,JAG2,JUNB,KBTBD8,KCNQ4,KDF1,KDM2B,KDM4C,KDM6A,KDM6B,KEAP1,KIAA1217,KIF16B,KIF20B,KITLG,KLF2,KLF4,KLHL12,KRT19,LAMA3,LAMA5,LAMB1,LAMB3,LATS1,LBX1,LEF1,LEO1,LFNG,LHFPL5,LHX1,LHX2,LIF,LIG4,LMO4,LOXL3,LRIG1,LRIG3,LRP4,LRP5,LRP6,LUZP1,MAFB,MAFF,MAFG,MAN2A1,MAPK1,MAPK3,MBD2,MBD3,MBNL1,MBTD1,MDFI,MED21,MEF2C,MEGF8,MEOX1,MEOX2,MESP1,MESP2,MFAP2,MFN2,MFRP,MIB1,MIXL1,MKKS,MKS1,MMP14,MMP15,MMP16,MMP8,MMP9,MSGN1,MSH2,MSX1,MSX2,MTHFD1,MTHFD1L,MYCN,MYF6,MYH3,MYH6,MYH9,MYO1E,NANOG,NASP,NBN,NCAPG2,NCOA1,NDEL1,NDRG4,NDST1,NES,NEUROD1,NEUROG1,NF1,NF2,NIPBL,NKX2-5,NKX2-6,NKX3-1,NKX3-2,NLE1,NMT1,NOG,NOLC1,NOS3,NOTCH1,NOTCH4,NOTO,NPHP3,NPM2,NR4A3,NR5A2,NRG1,NRP1,NSDHL,OCRL,OOEP,OSR1,OTX1,OTX2,OVOL2,PAF1,PALB2,PAX2,PAX5,PAX7,PAX8,PBX1,PBX2,PCDH12,PCDH8,PCGF2,PCSK5,PCSK6,PDCD6,PDGFA,PDGFB,PDGFC,PDZD7,PEF1,PFN1,PGAP1,PHACTR4,PICK1,PITX1,PITX2,PKD1,PKD2,PKDCC,PLAC1,PLCD3,PLCG1,PLD6,PLG,PLK4,PLXNA2,PLXNB2,POFUT2,POGLUT1,POLE,POLG2,POU3F4,POU4F3,PPP1R13L,PPP2R3A,PRDM1,PRICKLE1,PRKACA,PRKAR1A,PRKDC,PRKRA,PROX1,PRPF19,PRRX1,PSEN1,PSMC3,PSMC4,PTCH1,PTF1A,PTK7,PTPRR,PYGO2,RAB14,RAD23B,RAI2,RALA,RARA,RARB,RARG,RARRES2,RASA1,RBBP8,RBM46,RBP4,RBPJ,RBPMS2,RDH10,RECK,RET,RIC8A,RICTOR,RIPPLY1,RIPPLY2,RIPPLY3,RNASEH2B,RNF2,ROR2,RPL38,RPL7L1,RPS6,RRN3,RRP7A,RSPO2,RSPO3,RTF1,RUNX2,RXRA,RYR2,SALL2,SATB2,SBDS,SCEL,SCRIB,SCT,SCX,SDC4,SEC24B,SEC24D,SEMA3A,SEMA3C,SEMA4C,SETD2,SETDB2,SF3B6,SFRP1,SFRP2,SH2B3,SHOX2,SHROOM3,SIM2,SIX2,SKI,SKIL,SLC30A1,SLC34A2,SLC39A3,SLC9A3R1,SLITRK6,SMAD2,SMAD4,SMAD5,SMO,SNAI1,SOBP,SOCS3,SOD1,SOS1,SOX10,SOX11,SOX17,SOX18,SOX2,SOX4,SOX7,SOX8,SOX9,SP8,SPIC,SPINT1,SPRY2,SRF,SRSF1,SSBP3,ST14,STIL,STK4,STOX2,STPG4,STRA6,STRC,SUFU,SULF2,T,TAB1,TAF8,TAL1,TANC2,TAPT1,TBC1D32,TBX1,TBX15,TBX2,TBX20,TBX3,TBX5,TBX6,TCF15,TCF21,TCOF1,TDG,TDGF1,TDRD5,TEAD2,TEAD3,TEAD4,TENM4,TET3,TFAP2A,TFEB,TGFB1,TGFB1I1,TGFB2,TGFBR1,TGFBR2,TH,THOC2,THOC5,TIE1,TIFAB,TLE6,TLX2,TMED2,TMEM100,TMEM107,TMEM231,TMIE,TNF,TNFAIP1,TOP1,TOP2A,TP63,TPO,TPRA1,TRA2B,TRAF3IP1,TRAF6,TRIM28,TRIM71,TRIP12,TSC2,TTPA,TULP3,TWIST1,TXNRD1,UBTFL1,USH1C,USH1G,USP22,VANGL2,VASH1,VASH2,VASP,VAX2,VEGFA,VEGFC,VPS52,VTN,WDR60,WDTC1,WLS,WNT1,WNT11,WNT16,WNT3,WNT3A,WNT4,WNT5A,WNT6,WNT7A,WNT7B,WNT8A,WNT8B,WNT9A,WNT9B,XAB2,XRCC2,YBX1,YBX3,YTHDF2,ZBTB16,ZBTB17,ZEB1,ZFAND5,ZFAT,ZFP36L1,ZFPM1,ZFPM2,ZIC1,ZIC3,ZMIZ1,ZNF281,ZNF335,ZNF358,ZNF830,ZP3,ZPR1	TetrapodAncestor	143.629
GO.Biological.Process	GO:0001655	urogenital.system.development	190	5.812090e-148	7.507477e-144	3.951304e-146	1.207923e+0	ACAT1,ACD,ACE,ACTA2,ACVR2B,ADAMTS1,ADAMTS16,ADIPOQ,AGT,AGTR1,AGTR2,AHI1,AKR1B1,ALOX15B,AMER1,AMH,ANGPT1,ANGPT2,ANXA1,APH1A,AQP1,AQP11,AQP2,AR,ARG2,ARID5B,ARL3,BAG6,BASP1,BAX,BCL2,BCL2L11,BMP2,BMP4,BMP6,BMP7,BMPER,C1GALT1,C5orf42,CA2,CALB1,CAT,CD24,CD34,CDKN1C,CENPF,CEP55,CER1,CITED1,COL4A3,COL4A4,CRIP1,CTNNB1,CTSH,CYP19A1,DACT2,DCHS1,DCHS2,DCN,DLG1,DLG5,DLL1,EFNB2,EGR1,EMX2,ENPEP,EPCAM,EPHA4,EPHA7,EPHB2,EPHB3,ESR1,EYA1,FAT4,FEM1B,FGF1,FGF10,FGF2,FGFR1,FGFR2,FKBP4,FMN1,FOXA1,FOXC1,FOXC2,FOXF1,FOXJ1,FRAS1,FRS2,FSTL3,GATA2,GATA3,GCNT3,GCNT4,GDF11,GDNF,GLI2,GLI3,GPC3,GPR4,GREM1,GZF1,HAS2,HES1,HES5,HEYL,HNF1B,HPGD,ID3,ID4,IFT140,IFT20,IQGAP1,ITGA3,ITGA8,ITGB4,JAG1,JMJD6,KCNJ8,KIF26B,KIRREL3,KLF15,KLHL3,LAMA5,LGR4,LGR5,LHX1,LRP4,LRRK2,MAGI2,MEF2C,MME,MPST,MPV17,MTSS1,MYC,MYO1E,MYOCD,NF1,NFIA,NIPBL,NKX3-1,NLE1,NOG,NOTCH1,NOTCH3,NPHP3,NPHS1,NPHS2,NRP1,ODC1,OSR1,OVOL1,PAX2,PAX8,PBX1,PCSK5,PDGFB,PDGFRB,PECAM1,PKD1,PKD1L3,PKD2,PKHD1,PLAG1,PLCE1,PODXL,POU3F3,PRKX,PROM1,PROX1,PSAP,PSAPL1,PTCD2,PTCH1,PTEN,PTPRO,PYGO2,RARA,RARB,RARG,RBP4,RDH10,REN,RET,RGN,ROBO2,RRM2B,RXRA,SDC4,SEC61A1,SEC63,SERPINB5,SFRP1,SGPL1,SIM1,SIX2,SLC34A1,SLIT2,SMAD2,SMAD4,SMAD5,SMAD7,SMARCC1,SMO,SOX11,SOX17,SOX4,SOX8,SOX9,SPRY1,SRD5A1,STAT1,STRA6,SULF2,TACSTD2,TBX18,TCF21,TEK,TFAP2A,TFAP2B,TGFB1,TGFB2,TGFBR1,TIPARP,TMED10,TNC,TNS2,TP63,TP73,TRAF3IP1,UBE3A,UMOD,UPK3A,VANGL2,VEGFA,WDR77,WFS1,WNK4,WNT1,WNT11,WNT4,WNT5A,WNT6,WNT7B,WNT9B,WWTR1,ZBTB16,ZNF354A	TetrapodAncestor	143.125
GO.Biological.Process	GO:0035239	tube.morphogenesis	191	8.826229e-148	1.140084e-143	5.969026e-146	1.206688e+0	ABL1,ACVR2B,ACVRL1,ADAMTS16,AGR2,AHI1,ALX1,APAF1,AR,AREG,ARHGAP35,ARID1A,ARL13B,ATOH8,B4GALT1,BBS4,BBS7,BCAS3,BCL10,BCL2,BCL2L11,BMP2,BMP4,BMP5,BMP7,BTRC,C2CD3,CASR,CCDC103,CCDC40,CCL11,CCM2,CELSR1,CFL1,CHD7,CITED1,COBL,CSF1,CSF1R,CSNK2B,CTNNB1,CTSH,CTSZ,DAB2IP,DACT1,DCHS1,DDR1,DEAF1,DLC1,DLG1,DLG5,DLL1,DLL4,DNAAF1,DVL1,DVL3,EDA,EDAR,EDN1,EFNB2,EGF,EGFR,ENG,EPB41L5,EPHA2,EPHA4,EPHA7,EPHB3,ESR1,ESRP2,EYA1,FAT4,FGF1,FGF10,FGF2,FGFR2,FMN1,FOXA1,FOXC2,FOXF1,FOXH1,FOXN4,FUZ,FZD1,FZD2,FZD3,FZD6,GATA3,GATA4,GATA6,GBX2,GDF2,GDNF,GLI2,GLI3,GNA13,GPC3,GREM1,GRHL2,GRHL3,GZF1,HAND1,HAND2,HES1,HES5,HHEX,HIF1A,HLX,HNF1B,HOXA1,ID2,IFT172,IFT52,IFT57,IHH,KDM2B,KDM5B,KDM6A,KIF20B,KIF26B,KLHL3,KRAS,LAMA5,LBX1,LEF1,LGR4,LGR5,LHX1,LHX2,LMO4,LRP5,LRP6,LUZP1,MEF2C,MEGF8,MESP1,MET,MIB1,MKKS,MKS1,MMP14,MSX2,MTHFD1,MTHFD1L,MTSS1,MYC,MYCN,NDRG4,NFATC4,NFIB,NIPBL,NKX2-3,NKX2-5,NKX3-1,NOG,NOTCH1,NOTCH4,NOTO,NPHP3,NR4A3,NRP1,OSR1,OVOL2,PAK1,PAX2,PAX8,PBX1,PFN1,PGR,PHACTR4,PITX2,PKD1,PKD2,PLXNB2,PLXND1,PML,PODXL,PRICKLE1,PRKACA,PRKD2,PRKX,PSEN1,PTCH1,PTK7,RALA,RARA,RARG,RASIP1,RBPJ,RBPMS2,RDH10,RET,RSPO2,RYR2,SCRIB,SDC4,SEC24B,SEMA3E,SEMA4C,SETD2,SETDB2,SFRP1,SFRP2,SHOX2,SHROOM3,SIX2,SKI,SLIT2,SMAD2,SMAD4,SMO,SOSTDC1,SOX10,SOX11,SOX17,SOX18,SOX4,SOX8,SOX9,SPINT1,SPRY1,SPRY2,SRC,SRF,ST14,STARD13,STIL,STK4,STRA6,SUFU,T,TACSTD2,TBX1,TBX2,TBX20,TBX3,TCF21,TEAD2,TGFB1,TGFB2,TGFBR2,TGM2,TIMELESS,TMED2,TNC,TP63,TRAF6,TRIM71,TSC2,TULP3,TWIST1,VANGL2,VASP,VDR,VEGFA,WNK4,WNT1,WNT11,WNT3A,WNT4,WNT5A,WNT6,WNT9B,ZEB1,ZIC3	TetrapodAncestor	142.943
GO.Biological.Process	GO:0031960	response.to.corticosteroid	192	3.256884e-147	4.206917e-143	2.191103e-145	1.359958e+0	AANAT,ABCA3,ABCB4,ABCC2,ACSBG1,ADAM9,ADCYAP1,ADIPOQ,AGL,AGTR2,AGXT,AIF1,AIFM1,ALAD,ALDH3A1,ALPL,ANXA1,ANXA3,APOA2,AQP1,AREG,ARG1,ATP2B1,AVPR1A,BAD,BCHE,BCL2,BGLAP,BMP6,CALCR,CASP3,CASP9,CCL1,CCL2,CCND1,CDKN1A,CDO1,CFLAR,CLDN1,CNGA3,COL1A1,CPN1,CPS1,CTGF,CYBA,CYBB,DDIT4,DNMT3B,DUSP1,EDN1,EGFR,EIF4E,EIF4EBP1,ENG,EPHX1,EPO,ERRFI1,FAS,FBXO32,FIBIN,FOS,FOSB,FOSL1,FOXO1,GBA,GHRHR,GHSR,GLB1,GNRH1,GOT1,GPER1,GPR83,GSTP1,HEY1,HMGB1,HNMT,HNRNPU,HSD11B2,HTR1B,IFNB1,IGFBP2,IGFBP7,IL10,IL1RN,IL22,IL6,ISL1,KLF9,KRAS,MAOB,MDK,METTL21C,MSTN,MYOD1,NEFL,NOTCH1,NPAS4,NR3C1,NTRK3,OXT,PAM,PAPPA,PARP1,PCK2,PCNA,PDCD7,PFKFB1,PPARGC1B,PTAFR,PTPRU,REST,S100B,SCGB1A1,SLIT2,SLIT3,SMYD3,SOX30,SRC,SRD5A1,SSTR2,SSTR3,SSTR4,SSTR5,STAR,STC1,TAT,TGFB1,TH,TNF,TPH2,TRIM63,TYMS,UBE2L3,UCN,UCN3,UCP3,UGT1A1,USP8,WNT7B,ZFP36,ZFP36L1,ZFP36L2	TetrapodAncestor	142.376
GO.Biological.Process	GO:0045580	regulation.of.T.cell.differentiation	193	6.832832e-147	8.825969e-143	4.573041e-145	1.401235e+0	ABL1,ADA,ADAM8,ANXA1,AP3D1,BAD,BCL6,BMP4,BRAF,CAMK4,CARD11,CBFB,CCL19,CD2,CD27,CD28,CD46,CD74,CD80,CD83,CD86,CR1,CTLA4,CYP26B1,DROSHA,DTX1,DUSP10,ERBB2,FANCA,FOXJ1,FOXN1,FOXP3,GATA3,GLI2,GLI3,HLX,HMGB1,IFNA2,IFNB1,IFNG,IFNL1,IHH,IL12A,IL12B,IL12RB1,IL15,IL18,IL1RL2,IL2,IL23A,IL23R,IL27,IL36B,IL4,IL6,IL7,IL7R,IRF1,IRF4,ITPKB,JAK3,LGALS9,LILRB2,LILRB4,LOXL3,METTL3,MYB,NCKAP1L,NFATC2,NFKBID,PIK3R6,PNP,PRDM1,PRELID1,PRKCZ,RAG1,RARA,RASGRP1,RC3H1,RIPK2,RUNX1,SART1,SASH3,SHB,SLC46A2,SMAD7,SOCS1,SOCS5,SOD1,SOS1,SOX13,SPINK5,SYK,TESPA1,TGFB1,TGFBR2,TMEM131L,TNFRSF18,TNFSF18,TNFSF9,VNN1,XBP1,ZAP70,ZBTB1,ZBTB16,ZBTB7B,ZC3H8,ZEB1,ZMIZ1,ZNF683	TetrapodAncestor	142.054
GO.Biological.Process	GO:0060411	cardiac.septum.morphogenesis	194	1.783064e-146	2.303184e-142	1.187208e-144	1.402267e+0	BMP4,BMP5,BMP7,BMPR1A,BMPR2,CHD7,CITED2,CYR61,DHRS3,EGLN1,ENG,FGFR2,FGFRL1,FZD1,FZD2,GATA4,GATA6,HAND1,HES1,HEY1,HEY2,HEYL,ISL1,JAG1,MDM2,MSX2,NKX2-5,NOG,NOTCH1,NOTCH2,NRP1,NRP2,NSD2,PITX2,PROX1,RARA,RARB,SEMA3C,SMAD4,SMAD7,SMO,SOX11,SOX4,TBX1,TBX2,TBX20,TBX3,TBX5,TGFB2,TGFBR1,TGFBR2,VANGL2,WNT11,WNT5A,ZFPM1,ZFPM2	TetrapodAncestor	141.638
GO.Biological.Process	GO:0009725	response.to.hormone	195	4.747463e-146	6.132298e-142	3.144768e-144	1.160802e+0	AANAT,ABCA2,ABCA3,ABCB4,ABCC2,ABCC8,ABCG1,ABHD2,ACACA,ACAT1,ACSBG1,ACSL1,ADAM9,ADCY2,ADCY3,ADCY4,ADCY5,ADCY8,ADCYAP1,ADIPOQ,ADIPOR1,ADIPOR2,ADRA1A,ADRA2A,AGL,AGRP,AGT,AGTR1,AGTR2,AGTRAP,AGXT,AHCYL1,AIF1,AIFM1,AKAP8,AKR1B1,AKT2,ALAD,ALDH3A1,ALPL,ANXA1,ANXA3,AP3S1,APC,APEX1,APOA2,APOB,APOBEC1,APPL1,AQP1,AR,AREG,ARG1,ARID1A,ARID1B,ASIP,ASNS,ATP1A1,ATP1A2,ATP2B1,ATP6AP1,ATP6V0A4,ATP6V0B,ATP6V0C,ATP6V0D1,ATP6V0D2,ATP6V0E1,ATP6V0E2,ATP6V1B1,ATP6V1B2,ATP6V1C1,ATP6V1C2,ATP6V1D,ATP6V1E1,ATP6V1E2,ATP6V1G1,ATP6V1G3,ATP6V1H,AVPR1A,AVPR1B,AVPR2,BAD,BAIAP2L2,BBS4,BCAR1,BCHE,BCL2,BGLAP,BMP4,BMP6,BMP7,BRAF,BRCA1,BRIP1,BSG,BTG2,C2CD5,CA2,CACNA1H,CACYBP,CALCOCO1,CALCR,CALR,CAMK2A,CAPN10,CARM1,CASP3,CASP9,CAT,CATSPER1,CATSPER2,CATSPER4,CATSPERB,CATSPERD,CAV1,CAV2,CCKAR,CCL1,CCL19,CCL2,CCL21,CCNA2,CCND1,CCNE1,CCR7,CD38,CDC5L,CDC6,CDK4,CDK7,CDKN1A,CDKN1B,CDO1,CFLAR,CGB1,CGB2,CITED1,CLDN1,CLDN4,CNGA3,COL1A1,CPEB1,CPEB2,CPN1,CPS1,CREB1,CRHBP,CRHR1,CRHR2,CRK,CRLS1,CRY1,CSH1,CSK,CSNK2B,CTGF,CTNNB1,CTSB,CTSH,CTSL,CYBA,CYBB,CYC1,CYFIP1,CYP11B1,CYP11B2,DAXX,DDIT4,DDX17,DDX5,DDX54,DENND4C,DHCR24,DNAJA1,DNMT3B,DSG1,DSG2,DUSP1,EDN1,EEF2K,EFNA5,EGFR,EGLN2,EGR1,EGR2,EIF2B1,EIF2B3,EIF2B4,EIF2B5,EIF4E,EIF4EBP1,EIF6,ENG,ENPP1,ENSG00000278139,EPHA8,EPHX1,EPM2AIP1,EPO,EREG,ERRFI1,ESR1,ESR2,ESRRA,ESRRB,ESRRG,F7,FABP3,FAS,FBXO32,FER,FGF21,FGF23,FHL2,FIBIN,FKBP4,FOS,FOSB,FOSL1,FOXC2,FOXO1,FOXO4,FSHB,FSHR,GAB1,GABRB1,GAL,GAS2L1,GATA6,GBA,GCGR,GCK,GCLM,GGH,GH1,GH2,GHR,GHRHR,GHSR,GIP,GJA1,GLB1,GLP1R,GLP2R,GNAI1,GNB2,GNG10,GNG11,GNG12,GNG13,GNG2,GNG3,GNG7,GNG8,GNRH1,GNRHR,GOT1,GPER1,GPHB5,GPLD1,GPR22,GPR83,GRB2,GRIP1,GSK3A,GSTP1,H3F3A,HADHA,HCLS1,HCRTR1,HCRTR2,HDAC4,HDAC5,HDAC9,HEY1,HHEX,HMGB1,HMGB2,HMGCS1,HNF4A,HNF4G,HNMT,HNRNPU,HPN,HSD11B2,HSF1,HTR1B,IDE,IFNB1,IGF1R,IGF2,IGFBP2,IGFBP5,IGFBP7,IL10,IL1RN,IL22,IL6,INHBA,INHBB,INPP5K,INS,INSIG2,IQGAP1,IRS1,IRS2,IRS4,ISL1,ITGA2,ITGA3,JAK2,JAK3,JUN,JUNB,KAT2B,KAT5,KDM3A,KHK,KL,KLF9,KRAS,LATS1,LATS2,LCN8,LEF1,LEP,LEPR,LHB,LHCGR,LMO2,LONP1,LOX,LPIN1,LRP5,LRP6,LYN,MAOB,MAPK1,MAPK3,MAS1,MAX,MB,MC4R,MDK,MDM2,ME1,MED13,MED14,MED17,MED24,MED30,MED4,MEF2C,MEN1,METTL21C,MGARP,MKKS,MMP14,MMP19,MMS19,MSTN,MTOR,MYOD1,NCOA1,NCOA3,NCOA4,NCOA6,NDEL1,NEFL,NFKB1,NKX3-1,NKX6-1,NME2,NOTCH1,NPAS4,NPC1,NPFFR2,NR0B1,NR0B2,NR1D1,NR1D2,NR1H2,NR1H3,NR1H4,NR1I2,NR2C1,NR2C2,NR2E3,NR2F6,NR3C1,NR4A1,NR4A2,NR4A3,NR5A2,NRIP1,NTRK3,NUP62,OGT,OPRK1,OR51E2,OTC,OXCT1,OXT,OXTR,P2RY4,P2RY6,PADI2,PAK1,PAM,PAPPA,PAQR5,PAQR6,PAQR7,PAQR8,PARP1,PAX8,PCK1,PCK2,PCNA,PDCD7,PDK2,PDPK1,PFKFB1,PGR,PGRMC2,PHB,PHEX,PHIP,PIAS1,PIAS2,PIAS3,PID1,PIK3C2A,PIK3CA,PIK3R1,PIK3R2,PIK3R3,PITX2,PKLR,PKM,PLA2G1B,PLN,PLPP1,PMEPA1,PNPT1,POR,PPARA,PPARD,PPARG,PPARGC1A,PPARGC1B,PRKAA1,PRKAA2,PRKACA,PRKACG,PRKAR1A,PRKAR1B,PRKAR2B,PRKCD,PRKCE,PRKCI,PRKCZ,PRKDC,PRL,PRLH,PRLR,PTAFR,PTEN,PTGDR,PTGER2,PTGER4,PTGFR,PTH,PTK2,PTK2B,PTN,PTPN1,PTPN11,PTPRA,PTPRU,PXN,QDPR,QRFPR,RAB13,RAB31,RAB8A,RAMP2,RAP1B,RARA,RARB,RARG,RB1,RBBP4,RBBP7,RBFOX2,RBM14,RDX,RELA,REN,RERG,REST,RETN,RHOQ,RNF14,RNF4,RNF40,ROBO2,RORB,RORC,RPE65,RWDD1,RXRA,RXRB,RXRG,S100B,SAFB,SCGB1A1,SESN2,SESN3,SFRP1,SFRP4,SH2B2,SHC1,SIK1,SIK2,SIRT1,SLC25A33,SLC26A5,SLC27A1,SLC2A1,SLC2A8,SLC30A10,SLC34A1,SLC5A5,SLC9A1,SLIT2,SLIT3,SMARCC1,SMYD3,SOCS2,SOCS7,SOGA1,SORBS1,SORD,SOS1,SOST,SOX10,SOX30,SP1,SPP1,SRC,SRD5A1,SRD5A2,SREBF1,SRF,SRSF4,SRSF5,SRSF6,SST,SSTR1,SSTR2,SSTR3,SSTR4,SSTR5,STAR,STAT1,STC1,STC2,STEAP2,STXBP4,TAC1,TADA3,TAT,TBC1D4,TCIRG1,TEK,TFF1,TGFB1,TGFB1I1,TGFB2,TGFBR2,TH,THBS1,THRA,THRAP3,THRB,TIMP1,TIMP2,TIMP4,TLR2,TNC,TNF,TNFSF10,TPH2,TRIB3,TRIM63,TRIP4,TRPV1,TSHB,TSHR,TSPO,TUB,TUSC5,TXN2,TXNIP,TYMS,UBE2L3,UBE3A,UBR5,UCN,UCN3,UCP1,UCP2,UCP3,UGT1A1,UMODL1,UPRT,UQCRFS1,USF1,USP8,VAMP2,VDR,WDTC1,WNT1,WNT10B,WNT7B,XBP1,YAP1,YWHAG,YWHAH,YY1,ZFP36,ZFP36L1,ZFP36L2,ZNF106	TetrapodAncestor	141.212
GO.Biological.Process	GO:0001101	response.to.acid.chemical	196	3.391390e-145	4.380658e-141	2.235030e-143	1.249103e+0	AACS,AANAT,ABCA1,ABCB4,ABCC2,ABL2,ACACA,ACER2,ACSL1,ADIPOQ,ADNP2,AIFM1,AKAP8,AKR1B1,ALAD,APOB,AQP1,AQP2,AQP3,ARG1,ASCL1,ASNS,ASXL1,ATP2B4,AVPR1A,BAD,BCHE,BCL11A,BCL2L1,BMP6,BRINP1,BRINP2,BRINP3,CAPN2,CASP3,CASTOR1,CAT,CCL19,CCL2,CCL21,CCNB1,CCR7,CD36,CD38,CD9,CDK4,CDKN1B,CDKN2D,CDO1,CEBPB,CFL1,CHUK,CLDN1,CLK2,COL16A1,COL18A1,COL1A1,COL1A2,COL3A1,COL5A2,COL6A1,CPEB1,CPEB4,CPS1,CPT1A,CREB1,CRLS1,CTGF,CTSH,CYBA,CYBB,CYP26B1,DGAT2,DHFR,DHODH,DKK1,DNMT3A,DUSP1,E2F1,EDN1,EEF2,EGFR,EGR1,EPHA3,F7,FABP3,FFAR1,FFAR2,FFAR3,FGF21,FGFR2,FIS1,FOXO1,FZD10,FZD4,FZD7,GCLM,GDAP1,GIP,GIPR,GJA1,GJB3,GLDC,GLRA1,GLRA2,GLRA3,GLRA4,GLRB,GNG2,GNRH1,GPRC6A,GRIN1,GSN,GSS,GSTP1,HAMP,HDAC2,HLCS,HMGCL,HNRNPD,HPCA,HSD17B2,HSF1,HTRA2,ID3,IGF2R,IGFBP2,IGFBP7,IL6,INSIG2,IPO5,ITGA2,KCNK4,KCNMB1,KLF4,KRT13,LAMTOR2,LAMTOR3,LAMTOR4,LARS,LDLR,LEP,LRP11,LTK,LYN,MTHFR,MTOR,MYB,MYOG,NAIP,NCOA1,NEURL1,NFATC4,NME1,NME2,NR1H4,NTRK1,NTRK2,NTRK3,OGG1,OPA1,OR51E2,OSR1,OTC,OVCA2,OXT,P2RY4,P2RY6,PAX2,PCK1,PCNA,PDGFB,PDGFC,PDGFD,PDGFRB,PDK3,PEMT,PID1,PIK3C3,PINK1,PKD2,PPARG,PPARGC1A,PRKAA1,PRKAA2,PRKCE,PTAFR,PTCH1,PTGDR,PTGER2,PTGER4,PTGES,PTGFR,PTK2B,PTK7,PTN,RARA,RARG,RBP4,RELA,RET,RORB,RPTOR,RRAGA,RRAGD,RXRA,SCGB1A1,SESN2,SESN3,SETX,SFRP1,SH3BP4,SHMT1,SIPA1,SLC10A3,SLC1A2,SLC22A6,SLC26A5,SLC38A9,SLC6A4,SMARCD1,SNRNP70,SNW1,SOCS1,SOX9,SPAAR,SRC,SREBF1,SST,STRA8,T,TBX1,TEAD2,TESC,TH,TIE1,TLR2,TMBIM6,TMEM161A,TNC,TNF,TRIML2,TWF2,TYMS,UBR1,UBR2,UCP1,UCP2,UFL1,WNT10B,WNT11,WNT3,WNT3A,WNT5A,WNT6,WNT7B,WNT8A,WNT8B,WNT9A,WNT9B,XBP1,XRCC5,YES1,YY1,ZC3H12A,ZEB1,ZNF354A	TetrapodAncestor	140.358
GO.Biological.Process	GO:1903827	regulation.of.cellular.protein.localization	197	3.500604e-145	4.521730e-141	2.295295e-143	1.190168e+0	ABCA12,ABHD17A,ABHD17B,ABHD17C,ABLIM3,ACSL3,ACSM6,ADIPOQ,AGER,AGR2,AGTR2,AKT2,ANGPT1,ANK3,AP2M1,APC,APC2,APOD,APP,APPL1,AR,ARF6,ARHGEF16,ASTN2,ATG13,ATP13A2,ATPIF1,AXIN2,B3GAT3,BAD,BAG4,BAMBI,BAP1,BARD1,BCAP31,BCAS3,BCL2,BCL2L1,BCL2L11,BCL3,BDNF,BICD1,BID,BMP4,BMP6,BMP7,BMPR1A,BNIP3L,BRSK2,C1QTNF3,C2CD5,C8orf4,CABP1,CAMK1,CASP8,CAV3,CCDC22,CCDC88A,CCL19,CCL2,CCNE1,CCNE2,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,CD27,CD2AP,CD36,CDC42,CDCA5,CDH1,CDH2,CDK1,CDK5,CDK5R1,CDKL2,CDKN1A,CEMIP,CENPQ,CEP250,CEP72,CHERP,CHP1,CHRM1,CIB1,CLDN18,CLIP3,CLTC,CNPY4,CNST,COMMD1,CRIPT,CROCC,CSF3,CSK,CSNK1E,CSNK2A1,CSNK2A2,CTDSPL2,CTNNB1,CYB5R1,DAB2,DAB2IP,DACT1,DACT3,DCLK3,DDRGK1,DDX58,DERL2,DERL3,DKC1,DLG1,DMAP1,DMTN,DNAJA1,DNAJC27,DPP10,DTWD2,DTX3L,DVL1,DVL3,DYNLL1,DYNLL2,DYRK2,E2F1,ECT2,EDA,EDAR,EDEM1,EDEM2,EGF,EGFR,EIF2AK3,ELMOD1,EPB41,EPB41L2,EPHA2,EPHA3,EPHB2,ERBB2,ERBB4,EZR,F2,F2R,FAF1,FAM20B,FAM89B,FBXO4,FBXW11,FBXW7,FERMT1,FIS1,FLCN,FLNA,FZD1,FZD5,FZD7,FZD9,G3BP2,GAS6,GBF1,GCC2,GDI1,GLI3,GNAI1,GNAQ,GNL3,GNL3L,GOPC,GPD1L,GPER1,GPHA2,GPM6B,GREM1,GSK3A,GSN,GTSE1,H2AFY,HAX1,HCLS1,HDAC3,HDAC8,HES1,HHAT,HNMT,HPCA,HPS4,HSP90AB1,HSPH1,HTRA2,ICE1,IFI27,IFNG,IFNL3,IGF1,IL10,IL12B,IL18,IL18R1,IL1B,IL23A,IL6,INPP5K,INS,IPO5,IQGAP1,ITGA3,ITGAM,ITGAX,ITGB1,JAK2,JUP,KALRN,KANK1,KAT7,KCNAB2,KCNB1,KCNE1,KCNJ11,KCNN3,KDM1A,KEAP1,KIF20B,KIF5B,LACRT,LCP1,LDLRAP1,LEP,LEPROT,LEPROTL1,LGALS9,LIF,LILRB4,LITAF,LMNA,LRIG2,LRP1,LRP4,LRRC15,LRRK2,LYPD1,LYPLA1,LZTFL1,MAPK1,MAPK14,MAPK8,MAPT,MBTPS1,MCRS1,MDFI,MDM2,MESD,MFF,MIEF1,MIEF2,MIS18A,MRGPRE,MSN,MTOR,MYBPC1,MYO1C,NDC80,NDEL1,NECAB2,NEDD4L,NF1,NF2,NGFR,NKD2,NMD3,NMT1,NMUR1,NOL3,NOV,NPEPPS,NPM1,NPTN,NRG1,NUCB1,NUMB,NUP54,NUP58,NUP62,NUTF2,OAZ1,OAZ2,OGG1,OS9,OTUD7B,PAK1,PARD6A,PARK7,PARL,PARP1,PARP10,PARP9,PBLD,PCM1,PCNT,PDCD10,PDCD5,PDE2A,PDPK1,PEMT,PICALM,PID1,PIK3R1,PIK3R2,PIN1,PINK1,PINX1,PKD1,PKD2,PKDCC,PKIA,PKIG,PLK1,PLK3,PLS1,PMAIP1,POLR1A,POLR3A,PPFIA1,PPP1R13B,PPP2R5A,PPP3CA,PPP3CC,PPP3R1,PRDX1,PRELID3A,PRKACA,PRKCD,PRKCE,PRKCH,PRKCI,PRKN,PRR5L,PSEN1,PSMB7,PSMD10,PSMD8,PTN,PTPN1,PTPN11,PTPN14,PYDC2,RAB11B,RAB11FIP2,RAB11FIP5,RAB23,RAB29,RAC2,RALB,RAPGEF3,RASSF5,RB1,RBCK1,RBM22,RBPMS,RDX,RER1,RHOG,RHOQ,RHOU,RIPOR1,RNF31,RPL28,RTN4,RUFY3,RUVBL1,SAPCD2,SEC16B,SELENOI,SEMA5A,SESN2,SETD2,SFN,SFRP2,SFRP5,SH3GLB1,SH3TC2,SIAH3,SIRT1,SIRT4,SLC35D3,SLC51B,SLC9A3R1,SMAD4,SMO,SNAI2,SNIP1,SORBS1,SORL1,SOX4,SP100,SPHK1,SPIDR,SPPL3,SQSTM1,SRC,SREBF1,SREBF2,SRI,STARD7,STOM,STX3,STX4,STX6,STX7,SUFU,SULF2,SVIP,SYT11,TAX1BP3,TBC1D10C,TCP1,TDRD12,TENM1,TERF1,TERT,TFDP2,TGFB1,TGFBR1,THRA,TLR2,TLR3,TLR4,TLR9,TM9SF4,TMBIM1,TMEM110,TMEM173,TMEM30B,TMEM59,TNF,TNFSF14,TOMM7,TONSL,TOR1A,TP53,TP53BP2,TP53INP2,TP63,TP73,TPR,TRAPPC12,TREM2,TRIM28,TRIM29,TRIM8,TRIP6,TSGA13,TXN,U2AF1,U2AF2,UBAC2,UBE2D3,UBE2G2,UBE2J1,UBE2J2,UBE2L3,UBL5,UBR5,UGCG,UHMK1,USP36,VAMP2,VAMP8,VHLL,VIL1,VPS11,VPS35,VPS4A,VTI1B,WAPL,WBP11,WDR46,WDR75,WNK3,WNT3A,WNT5A,WRAP53,WWTR1,XPO4,XPO5,YOD1,YWHAB,YWHAE,YWHAG,YWHAH,YWHAZ,ZBED3,ZBTB17,ZC3H12A,ZDHHC8,ZIC1,ZMYND8,ZPR1	TetrapodAncestor	140.345
GO.Biological.Process	GO:0001818	negative.regulation.of.cytokine.production	198	6.710752e-145	8.668278e-141	4.377918e-143	1.329232e+0	ACP5,ADIPOQ,AGER,AKAP8,ANGPT1,ANXA1,ANXA4,APOA1,APOA2,APOD,ARG1,ARG2,ARRB1,ARRB2,ASB1,AXL,BANK1,BCL3,BCL6,BPI,BST2,BTK,C1QBP,C1QTNF3,C5orf30,CACTIN,CARD16,CARD17,CARD18,CD24,CD274,CD2AP,CD34,CD83,CD96,CDH3,CHID1,CIDEA,CMKLR1,CRYBA1,CSK,DDX58,DLL1,EPHA2,EPX,ERRFI1,EZR,F2,F2RL1,FFAR4,FGFR1,FN1,FOXJ1,FOXP3,FURIN,GAS6,GATA3,GATA6,GBA,GHSR,GPATCH3,GPNMB,GPR18,GSTP1,HAVCR2,HDAC7,HGF,HMGB1,HMOX1,HSF1,HSP90AB1,IDO1,IFNA2,IFNB1,IFNG,IFNL1,IKBKE,IL10,IL12A,IL12B,IL13,IL1R2,IL1RL1,IL20RB,IL23A,IL23R,IL33,IL36RN,IL6,INHA,INHBA,INHBB,INPP5D,IRAK3,IRF3,ISG15,ITCH,JAK3,KAT5,KLF2,KLF4,LAPTM4B,LBP,LEF1,LGALS9,LGR4,LILRA4,LRRC32,MC1R,MEFV,MERTK,MUL1,NAV3,NCKAP1L,NDFIP1,NFKB1,NLRC3,NLRC5,NLRP7,NLRX1,NMI,NR1H4,NUTF2,ORM1,OTUD5,OTUD7B,PCBP2,PDCD1LG2,PGLYRP1,PGLYRP2,PGLYRP3,PIN1,PML,POMC,PRG2,PTGER4,PTPN22,PTPRS,PYCARD,PYDC2,RAC1,RARA,REL,RELB,RGCC,RNF125,RNF128,RNF135,RNF216,RPS27A,RPS6KA4,RPS6KA5,SARS,SCGB1A1,SIGIRR,SLC11A1,SMAD7,SOCS5,SSC5D,SYT11,TAX1BP1,TBK1,TGFB1,TGFB2,THBS1,TIA1,TIGIT,TLR4,TLR6,TLR9,TNF,TNFAIP3,TNFRSF21,TNFRSF9,TRAF3,TRAF3IP1,TRAIP,TRIB2,TRIM25,TSPO,TWIST1,UBA7,UBC,UBE2L6,UFD1,VSIG4,WNT11,XCL1,YY1,ZC3H12A,ZFP36,ZFPM1	TetrapodAncestor	140.062
GO.Biological.Process	GO:0060840	artery.development	199	1.279431e-144	1.652641e-140	8.304729e-143	1.423054e+0	ACVR2B,ACVRL1,ADAMTS9,AP2B1,APOB,APOE,ARID2,BMP4,BMPR1A,BMPR2,CHD7,COL3A1,DCTN5,DLL4,DNM2,ENG,EYA1,FOXC1,FOXC2,FOXF1,FOXH1,GLI3,HAND2,HES1,HEY1,HEY2,HOXA1,HPGD,JAG1,LOX,LOXL1,LRP1,LUZP1,MYLK,MYOCD,NDST1,NF1,NKX3-1,NOG,NOTCH1,NOTCH3,NPRL3,NRP1,PDGFRB,PKD2,PLXND1,PRDM1,PRICKLE1,PROX1,PRRX1,RBPJ,SEC24B,SMAD7,SNX17,SOX4,SRF,STRA6,SUFU,TAB1,TBX1,TBX2,TFAP2B,TGFB2,TGFBR1,VEGFA,WNT11,ZMIZ1	TetrapodAncestor	139.782
GO.Biological.Process	GO:0007162	negative.regulation.of.cell.adhesion	200	1.901602e-144	2.456299e-140	1.228150e-142	1.288117e+0	ABAT,ABL1,ACER2,ACTN4,ACVRL1,ADAM15,ADAM22,ADAMDEC1,ADAMTS18,ADIPOQ,ADORA2A,AJAP1,ANGPT1,ANGPT2,ANXA1,AP1AR,APOA1,APOD,ARG1,ARG2,ARHGAP6,ARHGDIA,ARHGDIB,ASS1,B4GALNT2,BCAS3,BCL6,BMP2,BMP4,C1QTNF1,CASK,CASP3,CBLL1,CCL21,CCL28,CCM2L,CD164,CD274,CD300A,CD74,CD9,CDH1,CDH13,CDKN2A,CEBPB,CLASP2,CLEC4G,COL1A1,CTLA4,CYP1B1,DAB1,DACT2,DLC1,DLG1,DLG5,DMTN,DSCAM,DTX1,DUSP22,DUSP3,EFNA5,EPB41L5,EPCAM,ERBB2,FBLN1,FGG,FOXJ1,FOXP3,FXYD5,FZD4,FZD7,GCNT2,GLI3,GNRH1,GPNMB,HAVCR2,HLX,HMGB1,HRG,IDO1,IFNA2,IFNB1,IFNL1,IHH,IL10,IL1RN,IL2,IL20RB,IL4,IRF1,ITCH,JAK2,JAK3,JAM2,KANK1,KLF4,KNG1,LAX1,LGALS1,LGALS3,LGALS9,LILRB2,LOXL3,LPXN,LRRC32,MAD1L1,MAD2L2,MELTF,MEN1,METTL3,MIA3,MMP14,MUC1,MYADM,NDFIP1,NF1,NF2,NFKBID,NOTCH1,PAG1,PAWR,PDCD1LG2,PDE5A,PELI1,PHLDB2,PIK3R1,PLA2G2D,PLA2G2F,PLET1,PLG,PLXNB1,PLXNB2,PLXNC1,PLXND1,PODXL,PPARA,PRKAR1A,PRKCD,PRKG1,PTEN,PTK2,PTPN11,PTPN22,PTPRO,RASA1,RC3H1,RCC2,RDX,RGCC,RIPOR2,RND1,SCGB1A1,SDC4,SEMA3E,SEMA4D,SEMA5A,SERPINE2,SIPA1,SMAD7,SNAI2,SOCS5,SOCS6,SPACA7,SPN,SPOCK1,SRC,TACSTD2,TARM1,TBCD,TGFB1,TGFBI,THBS1,TIGIT,TMEM131L,TNC,TNFAIP8L2,TNFRSF14,TNFRSF21,TNFSF18,TNR,UBASH3B,VSIG4,VTCN1,WNT1,XCL1,YTHDF2,ZC3H8,ZNF703	TetrapodAncestor	139.61
GO.Biological.Process	GO:0002065	columnar/cuboidal.epithelial.cell.differentiation	201	2.642075e-144	3.412768e-140	1.697895e-142	1.397181e+0	ABL1,AGR2,ASCL1,ATOH1,B9D1,BMP2,BMP4,BMP5,BMP6,C1GALT1,CBFA2T2,CDH2,CDK6,CDKN1A,CLIC5,DLL1,DLX3,EMX1,FAM20C,FGFR1,FGFR2,FOXA1,GATA4,GATA5,GATA6,GPAT4,HES1,HES5,HIF1A,IL31RA,INSM1,JAG1,JAG2,KLF5,LEF1,LHFPL5,LRTOMT,MCOLN3,MEN1,NEUROD1,NKX3-2,NKX6-1,NOTCH1,PAFAH1B1,PDPK1,PDZD7,POU4F3,PRDM1,PROX1,RARA,RARB,RARG,RBPJ,RFX3,RFX6,ROS1,RXRA,SCRIB,SEC24B,SIDT2,SLC4A7,SLC9A3R1,SLITRK6,SMO,SOD1,SOX11,SOX4,STRC,TIGAR,TMC1,TMEM231,TP63,TYMS,USH1C,VHLL,WDR77,WNT11,WNT4,WNT5A,YIPF6	TetrapodAncestor	139.467
GO.Biological.Process	GO:0050817	coagulation	202	7.739953e-143	9.997697e-139	4.949355e-141	1.293150e+0	A2M,ADAMTS13,ADORA2A,ADRA2A,ADRA2B,ADRA2C,AK3,AKAP1,AKAP10,ANO6,ANXA5,APOH,ARRB1,ARRB2,AXL,BLOC1S3,BLOC1S4,C1GALT1C1,C1QBP,C4BPB,CAPZA2,CAPZB,CARMIL1,CD36,CD40,CD59,CD9,CDC42,CLEC1B,COL1A1,COL1A2,COL3A1,CPB2,DGKA,DGKB,DGKD,DGKE,DGKG,DGKI,DGKK,DGKQ,DGKZ,DOCK11,DOCK6,DOCK8,DOCK9,DTNBP1,EHD1,EHD2,EHD3,ENPP4,ENSG00000259753,ENTPD2,F10,F11,F12,F13A1,F13B,F2,F2R,F2RL1,F2RL3,F3,F5,F7,F8,F9,FBLN1,FCER1G,FERMT3,FGG,FIBP,FLNA,FZD6,GAS6,GATA2,GATA3,GATA4,GATA5,GATA6,GGCX,GNA11,GNA12,GNA13,GNA14,GNA15,GNAQ,GNAS,GNG2,GP1BA,GP1BB,GP5,GP6,GP9,H3F3A,HBB,HBD,HBE1,HBG1,HBG2,HDAC1,HDAC2,HIST1H3H,HIST1H3I,HIST1H3J,HIST2H3A,HIST2H3C,HIST2H3D,HMG20B,HNF4A,HPS4,HPS5,HRG,HSPB1,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNB1,IL6,IRF1,IRF2,ITGA2,ITGA2B,ITPK1,ITPR1,ITPR2,ITPR3,JAK2,JMJD1C,KDM1A,KLKB1,KNG1,LAT,LCK,LCP2,LMAN1,LYN,MAFF,MAFG,MAPK1,MAPK3,MERTK,METAP1,MFN2,MICAL1,MMRN1,MYH9,MYL9,P2RX2,P2RX3,P2RX4,P2RX5,P2RX6,P2RX7,P2RY1,PABPC4,PAFAH2,PAPSS2,PDGFC,PDGFD,PDPK1,PDPN,PF4,PF4V1,PHF21A,PIK3CA,PIK3CD,PIK3CG,PIK3R1,PIK3R5,PIK3R6,PLAT,PLAU,PLCG2,PLEK,PLG,PLSCR1,PRCP,PRKACA,PRKACG,PRKAR1A,PRKAR1B,PRKAR2B,PRKCA,PRKCB,PRKCD,PRKCE,PRKCG,PRKCH,PRKCQ,PROC,PROCR,PROS1,PROZ,PTPN11,RAB27A,RAB5A,RAC1,RAC2,RAD51B,RAD51C,RAF1,RAP2B,RBSN,RCOR1,RHOG,SAA1,SCUBE1,SEMG1,SEMG2,SERPINA1,SERPINA10,SERPINA5,SERPINC1,SERPIND1,SERPINE2,SERPING1,SH2B1,SH2B2,SH2B3,SLC7A11,SRC,SRF,STXBP1,SYK,TFPI,TFPI2,THBD,TLN1,TRPC3,TRPC6,TRPC7,TSPAN32,TYRO3,UBASH3B,VAV1,VAV2,VAV3,VCL,VKORC1,VPS45,VWF,WNT3A,YWHAZ,ZFPM1,ZFPM2	TetrapodAncestor	138
GO.Biological.Process	GO:0044255	cellular.lipid.metabolic.process	203	8.336811e-143	1.076866e-138	5.304758e-141	1.157511e+0	A3GALT2,A4GALT,AACS,ABCA4,ABCD1,ABCD2,ABCD3,ABHD1,ABHD12,ABHD15,ABHD2,ABHD5,ABHD6,ABO,ACAA2,ACACA,ACACB,ACAD10,ACAD9,ACADL,ACADM,ACADS,ACADVL,ACAT1,ACAT2,ACBD5,ACER1,ACER2,ACER3,ACHE,ACOT1,ACOT11,ACOT12,ACOT2,ACOT4,ACOT6,ACOT7,ACOT8,ACOX2,ACOX3,ACOXL,ACP6,ACSBG1,ACSBG2,ACSF2,ACSL1,ACSL3,ACSL4,ACSL5,ACSM1,ACSM2A,ACSM2B,ACSM3,ACSM4,ACSM5,ACSM6,ACSS1,ACSS2,ADH4,ADH5,ADH7,ADIPOQ,ADIPOR1,ADIPOR2,AGK,AGMO,AGPAT1,AGPAT2,AGPAT3,AGPAT4,AGPAT5,AGRN,AJUBA,AKR1B10,ALDH1A1,ALDH1A3,ALDH3A2,ALDH3B1,ALDH3B2,ALDH5A1,ALDH8A1,ALG1,ALG10B,ALG11,ALG13,ALG14,ALG2,ALG3,ALG8,ALG9,ALKBH7,ALOX15,ALOX15B,ALOX5,ALOX5AP,ALPI,AMACR,ANGPTL8,APOA1,APOA2,APOA4,APOA5,APOB,APOBEC1,APOBR,APOC1,APOC3,APOE,APOH,APOM,ARF1,ARF3,ARSD,ARSE,ARSF,ARSG,ARSH,ARSI,ARSJ,ARSK,ARV1,ASAH1,ASAH2,ATM,AUH,AWAT1,AWAT2,B3GALNT1,B3GALT2,B3GALT4,B3GNT5,B4GALNT1,B4GALNT2,B4GALT3,B4GALT4,B4GALT6,BAAT,BAX,BCO1,BCO2,BDH2,BMX,BPNT1,BRCA1,BTC,C3,CAT,CAV1,CAV3,CBR1,CBR4,CCDC71L,CD19,CD28,CD74,CD80,CD86,CDIPT,CDS1,CDS2,CEL,CEPT1,CERK,CERKL,CERS1,CERS2,CERS3,CERS4,CERS5,CES1,CES2,CETP,CHAT,CHKA,CHPT1,CLN3,CLN6,CLN8,CLPS,COQ2,CPNE3,CPNE6,CPNE7,CPS1,CPT1A,CPT1B,CPT1C,CPT2,CPTP,CRABP1,CRABP2,CRAT,CRLS1,CROT,CSF1R,CSNK1G2,CSNK2A1,CSNK2A2,CSNK2B,CTSA,CWH43,CYGB,CYP1A1,CYP1A2,CYP1B1,CYP26A1,CYP26B1,CYP26C1,CYP27C1,CYP2A13,CYP2A6,CYP2A7,CYP2B6,CYP2C18,CYP2C19,CYP2C8,CYP2C9,CYP2D6,CYP2F1,CYP2J2,CYP2S1,CYP2W1,CYP4A11,CYP4A22,CYP4F8,CYP4V2,DAGLA,DAGLB,DBI,DDHD1,DDHD2,DECR1,DEGS1,DEGS2,DGAT1,DGAT2,DGAT2L6,DGKA,DGKB,DGKD,DGKE,DGKG,DGKI,DGKK,DGKQ,DGKZ,DHDDS,DHRS3,DHRS4,DLD,DOLPP1,DPAGT1,DPEP1,DPM1,DPM2,DPM3,DRD2,ECH1,ECHDC1,ECHDC2,ECHS1,ECI1,ECI2,EDN1,EDN2,EFR3A,EFR3B,EGF,EGFR,EHHADH,ELOVL1,ELOVL2,ELOVL3,ELOVL4,ELOVL6,ELOVL7,ENPP2,ENPP6,ENPP7,ENSG00000249967,ENSG00000258417,ENSG00000260300,ENSG00000276490,ENSG00000278139,EPHX2,ERBB2,ERBB4,EREG,ESYT1,ESYT2,ETFA,ETFB,ETNK1,ETNK2,ETNPPL,FA2H,FAAH,FABP1,FABP12,FABP2,FABP3,FABP4,FABP5,FABP6,FABP7,FABP9,FADS1,FADS2,FADS3,FADS6,FAM126A,FAM135B,FAM213B,FAM57B,FAR1,FASN,FDFT1,FDPS,FGF1,FGF10,FGF16,FGF17,FGF18,FGF19,FGF2,FGF20,FGF22,FGF23,FGF3,FGF4,FGF6,FGF7,FGF9,FGFR1,FGFR2,FGFR3,FGFR4,FITM1,FITM2,FRS2,FUCA1,FUT3,FUT5,FUT6,FUT7,G6PC,GAB1,GAL3ST1,GAL3ST2,GAL3ST3,GAL3ST4,GALC,GALR2,GATA6,GBA,GBA2,GBGT1,GCDH,GDE1,GDPD1,GDPD3,GGT1,GGT2,GGT5,GGT7,GGTLC2,GGTLC3,GHR,GK,GK3P,GK5,GLA,GLB1,GLT6D1,GLYATL2,GM2A,GPAA1,GPAM,GPAT4,GPC1,GPC2,GPC3,GPC4,GPC5,GPC6,GPCPD1,GPD1,GPD1L,GPIHBP1,GPLD1,GRB2,GSTA1,GSTM2,GSTP1,HACD1,HACD2,HACD3,HACD4,HACL1,HADHA,HADHB,HAO1,HAO2,HBEGF,HDHD5,HEXA,HGF,HMGCR,HMGCS1,HMGCS2,HPGD,HPGDS,HRASLS2,HRASLS5,HSD17B12,HSD17B4,HSD17B8,HSPG2,HTD2,HTRA2,ICOS,IMPA1,IMPA2,IMPAD1,INPP1,INPP4A,INPP4B,INPP5B,INPP5D,INPP5J,INPP5K,INSIG2,IP6K1,IP6K3,IRS1,IRS2,ISPD,ITGB8,IVD,KDELC1,KDELC2,KDSR,KITLG,KL,LARGE1,LCAT,LCK,LCLAT1,LEP,LGALS13,LIPE,LIPF,LIPG,LIPH,LMF1,LPCAT4,LPIN1,LPIN3,LPL,LRAT,LRP1,LRP8,LTC4S,LYPLA1,LYPLA2,MAPK14,MAPK3,MAPKAPK2,MBOAT1,MBOAT7,MCAT,MCEE,MECP2,MECR,MET,MFSD2A,MGLL,MGST2,MGST3,MIF,MLYCD,MOGAT2,MORC2,MPDU1,MPPE1,MTM1,MTMR1,MTMR12,MTMR2,MTMR3,MTMR4,MTMR6,MTMR8,MTMR9,MUT,MVD,NAGA,NAPEPLD,NDUFAB1,NEU2,NEU3,NEU4,NKX2-3,NR1H2,NRG1,NRG2,NRG4,NSMAF,NUDT19,NUDT7,NUS1,OC90,OCRL,OLAH,OPN1LW,OPN1SW,ORMDL1,ORMDL2,ORMDL3,OSBPL10,OSBPL5,OXSM,P2RX7,PAFAH1B1,PAM,PARP9,PCCB,PCK1,PCTP,PCYT1A,PCYT1B,PCYT2,PDE3A,PDGFA,PDGFB,PDGFRB,PDPN,PDSS2,PECR,PEMT,PER2,PEX13,PEX2,PEX7,PGAP1,PGAP2,PGAP3,PGP,PGS1,PHOSPHO1,PHYH,PI4K2A,PI4K2B,PI4KB,PIGA,PIGF,PIGG,PIGH,PIGK,PIGM,PIGN,PIGP,PIGQ,PIGS,PIGT,PIGU,PIGW,PIGX,PIGZ,PIK3AP1,PIK3C2A,PIK3C2B,PIK3C2G,PIK3C3,PIK3CA,PIK3CD,PIK3CG,PIK3R1,PIK3R2,PIK3R3,PIK3R5,PIK3R6,PIKFYVE,PIP4K2A,PIP4K2B,PIP4K2C,PIP5K1A,PIP5K1B,PIP5K1C,PIP5KL1,PISD,PITPNM1,PITPNM3,PLA1A,PLA2G10,PLA2G12A,PLA2G12B,PLA2G15,PLA2G16,PLA2G1B,PLA2G2A,PLA2G2C,PLA2G2D,PLA2G2E,PLA2G2F,PLA2G3,PLA2G4A,PLA2G4B,PLA2G4D,PLA2G4E,PLA2G4F,PLA2G5,PLA2G6,PLA2G7,PLAA,PLB1,PLBD1,PLCB1,PLCE1,PLCG1,PLCG2,PLCH2,PLD1,PLD2,PLD6,PLEK,PLEKHA1,PLEKHA2,PLEKHA3,PLEKHA4,PLEKHA8,PLP1,PLPP1,PLPP2,PLPP3,PLPP4,PLPP5,PLPP6,PLPPR1,PLPPR2,PLPPR4,PLPPR5,PLSCR1,PM20D1,PMVK,PNLIP,PNPLA1,PNPLA2,PNPLA3,PNPLA4,PNPLA5,PNPLA6,POGLUT1,POR,PPARA,PPARD,PPARG,PPARGC1A,PPM1L,PPT1,PQLC3,PRG3,PRKAA1,PRKAA2,PRKAB1,PRKAG2,PRKAG3,PRKAR2B,PRKD1,PRKD2,PRKD3,PSAP,PSAPL1,PTDSS1,PTDSS2,PTEN,PTGDS,PTGES,PTGES2,PTGIS,PTGR1,PTGR2,PTGS1,PTPMT1,PTPN11,PTPN13,QKI,RAB14,RAB4A,RAB5A,RAB7A,RARRES2,RARRES3,RBP1,RBP2,RBP3,RBP4,RDH10,RDH13,RDH14,RDH5,RDH8,RETSAT,RLBP1,RPE65,RUFY1,SACM1L,SBF1,SCD,SCP2,SCPEP1,SDC2,SDC4,SDR16C5,SEL1L,SELENOI,SERAC1,SERINC1,SERINC2,SERINC3,SERINC4,SERINC5,SERPINA6,SESN2,SFTPB,SGMS1,SGPL1,SGPP1,SIRT1,SIRT2,SLC22A4,SLC25A17,SLC27A1,SLC27A2,SLC27A3,SLC27A4,SLC27A5,SLC27A6,SLC35C1,SLC44A1,SLC44A2,SLC44A3,SLC44A5,SMG1,SMPD1,SMPD2,SMPD3,SMPDL3B,SNCA,SOAT1,SOAT2,SPHK1,SPHK2,SPNS2,SPTLC1,SPTLC2,SPTLC3,SPTSSA,SPTSSB,SRD5A1,SSTR4,ST3GAL2,ST3GAL4,ST3GAL5,ST3GAL6,ST6GALNAC1,ST6GALNAC3,ST6GALNAC4,ST6GALNAC5,ST6GALNAC6,ST8SIA1,ST8SIA2,ST8SIA4,ST8SIA5,ST8SIA6,STAR,STARD10,STARD7,STRA6,STS,SUMF1,SYK,SYNJ1,SYNJ2,TAZ,TBXAS1,TECR,TECRL,TEX2,TH,THEM4,THEM5,THNSL2,TLR2,TLR9,TMEM150A,TMEM55A,TMEM55B,TMEM86B,TNFAIP8L3,TNFRSF1A,TPTE2,TRAT1,TTC7B,TTR,TYRP1,UCP3,UGCG,UGT1A1,UGT1A3,UGT1A8,UGT1A9,UGT8,VAC14,VAPA,VAPB,VAV1,XBP1,ZFYVE21	TetrapodAncestor	137.968
GO.Biological.Process	GO:0007596	blood.coagulation	204	1.578343e-142	2.038746e-138	9.993851e-141	1.292974e+0	A2M,ADAMTS13,ADORA2A,ADRA2A,ADRA2B,ADRA2C,AK3,AKAP1,AKAP10,ANO6,ANXA5,APOH,ARRB1,ARRB2,AXL,BLOC1S3,BLOC1S4,C1GALT1C1,C1QBP,C4BPB,CAPZA2,CAPZB,CARMIL1,CD36,CD40,CD59,CD9,CDC42,CLEC1B,COL1A1,COL1A2,COL3A1,CPB2,DGKA,DGKB,DGKD,DGKE,DGKG,DGKI,DGKK,DGKQ,DGKZ,DOCK11,DOCK6,DOCK8,DOCK9,DTNBP1,EHD1,EHD2,EHD3,ENPP4,ENSG00000259753,ENTPD2,F10,F11,F12,F13A1,F13B,F2,F2R,F2RL1,F2RL3,F3,F5,F7,F8,F9,FBLN1,FCER1G,FERMT3,FGG,FIBP,FLNA,FZD6,GAS6,GATA2,GATA3,GATA4,GATA5,GATA6,GGCX,GNA11,GNA12,GNA13,GNA14,GNA15,GNAQ,GNAS,GNG2,GP1BA,GP1BB,GP5,GP6,GP9,H3F3A,HBB,HBD,HBE1,HBG1,HBG2,HDAC1,HDAC2,HIST1H3H,HIST1H3I,HIST1H3J,HIST2H3A,HIST2H3C,HIST2H3D,HMG20B,HNF4A,HPS4,HPS5,HRG,HSPB1,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNB1,IL6,IRF1,IRF2,ITGA2,ITGA2B,ITPK1,ITPR1,ITPR2,ITPR3,JAK2,JMJD1C,KDM1A,KLKB1,KNG1,LAT,LCK,LCP2,LMAN1,LYN,MAFF,MAFG,MAPK1,MAPK3,MERTK,METAP1,MFN2,MICAL1,MMRN1,MYH9,MYL9,P2RX2,P2RX3,P2RX4,P2RX5,P2RX6,P2RX7,P2RY1,PABPC4,PAFAH2,PAPSS2,PDGFC,PDGFD,PDPK1,PDPN,PF4,PF4V1,PHF21A,PIK3CA,PIK3CD,PIK3CG,PIK3R1,PIK3R5,PIK3R6,PLAT,PLAU,PLCG2,PLEK,PLG,PLSCR1,PRCP,PRKACA,PRKACG,PRKAR1A,PRKAR1B,PRKAR2B,PRKCA,PRKCB,PRKCD,PRKCE,PRKCG,PRKCH,PRKCQ,PROC,PROCR,PROS1,PROZ,PTPN11,RAB27A,RAB5A,RAC1,RAC2,RAD51B,RAD51C,RAF1,RAP2B,RBSN,RCOR1,RHOG,SAA1,SCUBE1,SERPINA1,SERPINA10,SERPINA5,SERPINC1,SERPIND1,SERPINE2,SERPING1,SH2B1,SH2B2,SH2B3,SLC7A11,SRC,SRF,STXBP1,SYK,TFPI,TFPI2,THBD,TLN1,TRPC3,TRPC6,TRPC7,TSPAN32,TYRO3,UBASH3B,VAV1,VAV2,VAV3,VCL,VKORC1,VPS45,VWF,WNT3A,YWHAZ,ZFPM1,ZFPM2	TetrapodAncestor	137.691
GO.Biological.Process	GO:0007599	hemostasis	205	1.629598e-142	2.104952e-138	1.026806e-140	1.291684e+0	A2M,ADAMTS13,ADORA2A,ADRA2A,ADRA2B,ADRA2C,AK3,AKAP1,AKAP10,ANO6,ANXA5,APOH,ARRB1,ARRB2,AVPR2,AXL,BLOC1S3,BLOC1S4,C1GALT1C1,C1QBP,C4BPB,CAPZA2,CAPZB,CARMIL1,CD36,CD40,CD59,CD9,CDC42,CLEC1B,COL1A1,COL1A2,COL3A1,CPB2,DGKA,DGKB,DGKD,DGKE,DGKG,DGKI,DGKK,DGKQ,DGKZ,DOCK11,DOCK6,DOCK8,DOCK9,DTNBP1,EHD1,EHD2,EHD3,ENPP4,ENSG00000259753,ENTPD2,F10,F11,F12,F13A1,F13B,F2,F2R,F2RL1,F2RL3,F3,F5,F7,F8,F9,FBLN1,FCER1G,FERMT3,FGG,FIBP,FLI1,FLNA,FZD6,GAS6,GATA2,GATA3,GATA4,GATA5,GATA6,GGCX,GNA11,GNA12,GNA13,GNA14,GNA15,GNAQ,GNAS,GNG2,GP1BA,GP1BB,GP5,GP6,GP9,H3F3A,HBB,HBD,HBE1,HBG1,HBG2,HDAC1,HDAC2,HIST1H3H,HIST1H3I,HIST1H3J,HIST2H3A,HIST2H3C,HIST2H3D,HMG20B,HNF4A,HPS4,HPS5,HRG,HSPB1,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNB1,IL6,IRF1,IRF2,ITGA2,ITGA2B,ITPK1,ITPR1,ITPR2,ITPR3,JAK2,JMJD1C,KDM1A,KLKB1,KNG1,LAT,LCK,LCP2,LMAN1,LYN,MAFF,MAFG,MAPK1,MAPK3,MERTK,METAP1,MFN2,MICAL1,MMRN1,MYH9,MYL9,P2RX2,P2RX3,P2RX4,P2RX5,P2RX6,P2RX7,P2RY1,PABPC4,PAFAH2,PAPSS2,PDGFC,PDGFD,PDPK1,PDPN,PF4,PF4V1,PHF21A,PIK3CA,PIK3CD,PIK3CG,PIK3R1,PIK3R5,PIK3R6,PLAT,PLAU,PLCG2,PLEK,PLG,PLSCR1,PRCP,PRKACA,PRKACG,PRKAR1A,PRKAR1B,PRKAR2B,PRKCA,PRKCB,PRKCD,PRKCE,PRKCG,PRKCH,PRKCQ,PROC,PROCR,PROS1,PROZ,PTPN11,RAB27A,RAB5A,RAC1,RAC2,RAD51B,RAD51C,RAF1,RAP2B,RBSN,RCOR1,RHOG,SAA1,SCUBE1,SERPINA1,SERPINA10,SERPINA5,SERPINC1,SERPIND1,SERPINE2,SERPING1,SH2B1,SH2B2,SH2B3,SLC7A11,SRC,SRF,STXBP1,SYK,TFPI,TFPI2,THBD,TLN1,TRPC3,TRPC6,TRPC7,TSPAN32,TYRO3,UBASH3B,VAV1,VAV2,VAV3,VCL,VKORC1,VPS45,VWF,WNT3A,YWHAZ,ZFPM1,ZFPM2,ZNF385A	TetrapodAncestor	137.677
GO.Biological.Process	GO:0045637	regulation.of.myeloid.cell.differentiation	206	1.853700e-142	2.394424e-138	1.162342e-140	1.305614e+0	ACIN1,ACVR1B,ACVR2A,ADIPOQ,AGO1,AGO3,AGO4,ANKRD54,ASH2L,ATP6AP1,BGLAP,C1QC,CA2,CAMK4,CARTPT,CASP8,CBFB,CCL3,CCR1,CD101,CD74,CDC73,CDK6,CEBPB,CIB1,CLDN18,CREB1,CSF1,CSF3,CSF3R,CTNNB1,CUL4A,DLL1,DPY30,EIF6,EP300,ESRRA,ETS1,FADD,FAM210B,FAS,FES,FOS,FSHB,FSHR,FSTL3,GABPA,GATA2,GNAS,GP1BA,GPR171,GPR55,GPR68,H3F3A,HAX1,HCLS1,HDAC1,HIF1A,HIST1H3H,HIST1H3I,HIST1H3J,HIST1H4J,HIST1H4K,HIST1H4L,HIST2H3A,HIST2H3C,HIST2H3D,HIST2H4B,HIST4H4,HMGB1,HMGB2,HMGB3,HSPA9,IFNG,IL12B,IL17A,IL20,IL23A,IL23R,IL34,IL4,IL5,INHA,INHBA,INPP5D,IRF7,ISG15,ITGA2B,ITPKB,JAG1,JUN,KAT2B,KITLG,KLF10,KLF13,KMT2B,KMT2C,KMT2E,L3MBTL1,LEF1,LEO1,LEP,LGALS3,LHCGR,LIF,LILRB4,LRRC17,LYN,MAFB,MAPK14,MEF2C,MEIS1,MEIS2,MOV10,MTOR,MYC,MYL9,NCKAP1L,NDFIP1,NF1,NME1,NME2,NR4A3,OCSTAMP,PAF1,PF4,PIK3R1,POU4F1,PPARGC1B,PRKCA,PRKCB,PRKCQ,PRMT1,PRMT6,PTK2B,PURB,RAB7B,RARA,RARG,RASSF2,RB1,RBBP5,RBFOX2,RIPK1,RNF41,ROR2,RUNX1,SCIN,SETD1A,SFRP1,SIGLEC15,SLC9B2,SMAP1,SPI1,STAT1,TAL1,TESC,TFE3,THBS1,THPO,TJP2,TLR3,TLR4,TMEM178A,TMEM64,TNF,TNFSF11,TNRC6A,TNRC6B,TNRC6C,TRAF6,TRIB1,UBASH3B,WDR5,WDR61,ZBTB16,ZFP36,ZFP36L1,ZFPM1,ZNF16,ZNF675	TetrapodAncestor	137.621
GO.Biological.Process	GO:0044712	single-organism.catabolic.process	207	2.070366e-142	2.674292e-138	1.291928e-140	1.187985e+0	AADAT,AASS,ABAT,ABCD1,ABCD2,ABCD3,ABHD10,ABHD12,ABHD2,ABHD6,ACAA2,ACAD10,ACAD8,ACADL,ACADM,ACADS,ACADVL,ACAN,ACAT1,ACAT2,ACBD5,ACE,ACE2,ACER1,ACHE,ACMSD,ACOT4,ACOT8,ACOX2,ACOX3,ACOXL,ADA,ADA2,ADAM15,ADAMTS14,ADAMTS2,ADAMTS3,ADH4,ADH5,ADH7,ADIPOQ,ADO,ADORA1,ADPGK,ADPRM,AFMID,AGL,AGXT,AGXT2,AHCY,AICDA,AKR1A1,AKR1B10,AKR1D1,ALDH1A1,ALDH1B1,ALDH1L1,ALDH1L2,ALDH2,ALDH3A2,ALDH3B1,ALDH3B2,ALDH4A1,ALDH5A1,ALDH6A1,ALDH7A1,ALDOA,ALDOB,AMACR,AMBP,AMDHD2,AMFR,ANKZF1,AOX1,APOA1,APOA2,APOA4,APOA5,APOB,APOBEC1,APOBEC2,APOBEC3A,APOBEC3C,APOBEC3F,APOBEC3G,APOBEC3H,APOC3,APOE,ARG1,ASPA,ASPG,ATXN3,AUH,AUP1,BAD,BAG6,BCAN,BCAT1,BCAT2,BCKDHA,BCKDHB,BCKDK,BCO2,BDH1,BDH2,BGN,BLMH,BPGM,BRSK2,BSCL2,CALM1,CARNMT1,CARNS1,CBR3,CBS,CCDC47,CDA,CDO1,CEL,CLPS,CLPSL1,CLPSL2,COL10A1,COL11A1,COL12A1,COL13A1,COL15A1,COL18A1,COL1A1,COL1A2,COL25A1,COL26A1,COL2A1,COL3A1,COL4A3,COL4A4,COL4A5,COL4A6,COL5A1,COL5A2,COL5A3,COL6A1,COL6A2,COL6A3,COL6A5,COL6A6,COL7A1,COL8A1,COL8A2,COLQ,CPS1,CPT1A,CPT1B,CPT1C,CPT2,CRABP1,CRAT,CROT,CRYM,CSPG4,CTH,CTSB,CTSD,CTSL,CYP1A1,CYP1A2,CYP1B1,CYP24A1,CYP26A1,CYP26B1,CYP26C1,CYP27B1,CYP2A6,CYP39A1,CYP46A1,CYP4A11,CYP7A1,DAGLA,DAGLB,DBT,DCN,DCXR,DDAH1,DDHD1,DDHD2,DDO,DECR1,DERA,DERL1,DERL2,DERL3,DHDH,DHTKD1,DLD,DNAJB12,DNAJC10,DPEP1,DPYD,DZIP3,ECH1,ECHDC1,ECHDC2,ECHS1,ECI1,ECI2,EDEM1,EDEM2,EDEM3,EHHADH,ENO3,ENO4,ENOSF1,ENPEP,ENPP1,ENPP2,ENPP3,ENPP4,ENPP6,ENPP7,ENSG00000255730,ENSG00000258417,ENSG00000260643,ENSG00000284512,ENTPD2,ENTPD3,ENTPD4,ENTPD5,ENTPD6,ENTPD7,ERLIN1,ERLIN2,ESD,ETFA,ETFB,FAAH,FABP1,FABP12,FABP2,FABP3,FABP4,FABP5,FABP6,FABP7,FABP9,FAF2,FAH,FBXO2,FBXO6,FGF23,FMOD,FOXRED2,FTCD,FUCA1,FUCA2,FURIN,FUT1,FUT10,FUT2,FUT4,FUT5,FUT6,FUT7,FUT8,FUT9,G6PC,GAA,GALC,GALE,GALM,GALT,GAPDH,GAPDHS,GBA,GBA2,GCAT,GCDH,GCK,GCSH,GDA,GDE1,GDPD3,GET4,GK,GK3P,GK5,GLA,GLB1,GLDC,GLUD1,GLUD2,GLUL,GLYATL2,GLYCTK,GM2A,GNS,GOT1,GOT2,GPC1,GPCPD1,GPT,GPT2,GSTO2,GSTZ1,GYG1,GYG2,HAAO,HACL1,HADHA,HADHB,HAO1,HAO2,HDC,HERPUD1,HEXA,HGD,HIBCH,HINT1,HINT2,HK3,HM13,HMGCL,HMOX1,HMOX2,HNMT,HOGA1,HPD,HPRT1,HPSE,HRASLS,HRASLS2,HSD17B14,HSD17B4,HSP90B1,HSPA5,HYKK,IDNK,IDO1,IDO2,IDS,IDUA,IL4I1,IMPA1,IMPA2,INPP5K,ITPA,IVD,JKAMP,KERA,KHK,KIAA0368,KMO,KYAT1,KYNU,LDHA,LEP,LIPA,LIPE,LIPF,LIPG,LIPH,LIPJ,LIPK,LIPM,LIPN,LPIN1,LPIN3,LPL,LRCOL1,LRP5,LUM,MAN1B1,MAN2B1,MAN2B2,MAN2C1,MANBA,MARCH6,MCAT,MCCC1,MCCC2,MCEE,MECR,MGLL,MGST2,MIOX,MMP1,MMP10,MMP11,MMP12,MMP13,MMP14,MMP15,MMP16,MMP19,MMP20,MMP26,MMP27,MMP3,MMP7,MMP8,MMP9,MPST,MRC2,MTHFS,MTMR2,MTRR,MUT,NAGA,NAGK,NAPEPLD,NCEH1,NDUFAB1,NEIL1,NEIL2,NEU2,NEU3,NEU4,NOS1,NOS2,NOS3,NPL,NT5C,NT5C1A,NT5C1B,NT5C3A,NT5E,NT5M,NTHL1,NTSR1,NUDT1,NUDT12,NUDT15,NUDT16,NUDT18,NUDT19,NUDT4,NUDT5,NUDT7,NUDT9,OC90,OGDH,OGDHL,OGG1,OGN,OMD,OS9,OTC,OXCT1,OXCT2,P2RX7,PADI4,PAFAH1B1,PAFAH1B2,PAFAH2,PAH,PARP9,PCBD1,PCCB,PCYOX1,PCYOX1L,PDE10A,PDE1A,PDE1B,PDE2A,PDE3A,PDE4A,PDE4B,PDE4D,PDE5A,PDE7B,PDE8A,PDE8B,PDE9A,PDXP,PECR,PEPD,PEX13,PEX2,PEX7,PFKFB1,PFKFB2,PFKL,PFKP,PGAM1,PGAM2,PGAM4,PGK1,PGK2,PGM2,PGM2L1,PHKA1,PHKA2,PHKB,PHKG1,PHKG2,PHYH,PHYKPL,PKLR,PKM,PLA1A,PLA2G10,PLA2G12A,PLA2G12B,PLA2G15,PLA2G16,PLA2G1B,PLA2G2A,PLA2G2C,PLA2G2D,PLA2G2E,PLA2G2F,PLA2G3,PLA2G4A,PLA2G4B,PLA2G4D,PLA2G4E,PLA2G4F,PLA2G5,PLA2G6,PLA2G7,PLB1,PLBD1,PLBD2,PLCB1,PLCB3,PLCB4,PLCD3,PLCE1,PLCG1,PLCG2,PLCH1,PLCH2,PLCXD2,PLCXD3,PLCZ1,PLD1,PLD2,PLD3,PLD6,PLIN1,PNKD,PNLIP,PNLIPRP3,PNP,PNPLA1,PNPLA2,PNPLA3,PNPLA4,PNPLA5,PNPLA6,POMT1,POMT2,POR,PPARD,PPT1,PRELP,PRKN,PRODH,PRODH2,PRSS2,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PTEN,PYGB,QDPR,RAB7A,RARRES3,RBKS,RENBP,RHBDD1,RNF103,RNF121,RNF139,RNF175,RNF185,RNF5,RPE,SAMHD1,SARDH,SCARB1,SCP2,SDF2L1,SDS,SEC61B,SEL1L,SERPINA6,SESN2,SGPL1,SGSH,SGTA,SHMT1,SIRT2,SLC25A17,SLC25A21,SLC27A2,SLC27A4,SMPD1,SMPD3,SMPDL3A,SMPDL3B,SNX17,SORD,SPHK1,SRD5A2,STBD1,STS,STT3B,STUB1,SULT1A1,SULT1A2,SULT1C4,SULT2A1,SYNJ1,SYVN1,TAT,TBL1XR1,TDG,TDO2,THNSL2,TKFC,TKTL1,TMEM129,TMEM67,TMPRSS6,TMUB1,TOR1A,TREH,TRERF1,TRIM13,TRIM25,TST,TYMP,UBE2G2,UBE2J1,UBE2J2,UBE4A,UBQLN1,UBXN4,UBXN6,UBXN8,UFD1,UGGT1,UGT1A1,UGT1A4,UNG,UPB1,UPP1,UROC1,USP13,VCAN,VCP,WFS1,XDH,YOD1,YWHAH	TetrapodAncestor	137.573
GO.Biological.Process	GO:0071902	positive.regulation.of.protein.serine/threonine.kinase.activity	208	4.330725e-142	5.593997e-138	2.689422e-140	1.240248e+0	ACSL1,ADAM8,ADIPOQ,ADORA2B,ADRA2A,ADRA2B,ADRB2,AGER,AJUBA,AKAP13,ALK,ALS2,ARRB1,ATP2B4,AVPI1,BMP2,C1QTNF2,C5,C8orf4,CAB39,CALM1,CALM2,CALM3,CAMK1,CARD10,CARD14,CCL19,CCNB1,CCND1,CCND2,CCND3,CCNH,CCNK,CCNL1,CCNL2,CCNT2,CD24,CD40,CD74,CD81,CDC6,CDK1,CDK5R1,CDK5R2,CDKN1B,CEMIP,CHI3L1,CIB1,CKS1B,CKS2,COPS8,CSF1R,CSK,CSPG4,CXCR4,DAB2IP,DAXX,DBNL,DDX3X,DKK1,DRD4,DUSP19,DUSP6,DUSP7,DUSP9,DVL3,EDN1,EDN3,EGF,EGFR,EPGN,EPHA4,ERBB2,ERCC6,ERN1,ERN2,ERP29,ETAA1,EZH2,FAM20A,FAM58A,FGD2,FGF1,FGF10,FGF18,FGF2,FGFR1,FLT1,FRS2,FZD10,FZD4,FZD5,FZD8,GADD45A,GADD45B,GADD45G,GH1,GHR,GNG3,GRM4,HACD3,HGF,HRAS,HSP90AB1,HSPA2,HTR2A,HTR2B,IFNG,IGF1,IGF2,IKBKG,IL1B,INAVA,IQGAP1,IQGAP3,IRAK1,IRGM,ITGA1,KARS,KITLG,KRAS,LPAR1,LPAR3,LRRK2,MADD,MALT1,MAP2K2,MAP2K3,MAP2K4,MAP2K6,MAP2K7,MAP3K10,MAP3K11,MAP3K2,MAP3K21,MAP3K4,MAP3K5,MAP3K6,MAP3K7,MAP3K9,MAP4K1,MAP4K3,MAP4K4,MAPK1,MAPK10,MAPK11,MAPK14,MAPK3,MAPK8IP3,MAPKAPK2,MAPKAPK3,MAPKAPK5,MAPRE3,MAS1,MIF,MINK1,MLST8,MOS,MST1R,MTCP1,MUC20,MUL1,NEK10,NOD1,NOX4,NRG1,NRK,NTF3,NTRK3,P2RX7,PAK1,PAK3,PARP16,PDCD10,PDE5A,PDE6H,PDGFA,PDGFB,PDGFC,PDGFD,PDGFRB,PEA15,PIH1D1,PIK3CG,PIK3R5,PIK3R6,PKD1,PKD2,PKN1,PLA2G1B,PLCE1,PRKAA1,PROK1,PROK2,PROX1,PSMD10,PTK2B,PTPN1,PTPN11,RALB,RAPGEF2,RASGRP1,RGCC,RIPK1,RIPK2,ROBO1,ROR2,RPS27A,RPS3,RPTOR,S100A12,SAA1,SASH1,SHC1,SHC2,SIRT1,SLC27A1,SNCA,SOD1,SPAG9,SPDYA,SPRY2,SRC,STK24,STK26,STK4,STRADA,SYK,TAB1,TAB2,TAB3,TCL1A,TCL1B,TDGF1,TELO2,TENM1,TGFB1,THBS1,TIAM1,TIRAP,TLR3,TLR4,TLR6,TLR9,TMEM189-UBE2V1,TNF,TNFRSF10A,TNFRSF10B,TNFRSF11A,TNFSF11,TNFSF15,TNIK,TP73,TPD52L1,TRAF2,TRAF4,TRAF6,TRAF7,UBC,UBE2N,VANGL2,VEGFA,WNT5A,WNT7B,ZFP91	TetrapodAncestor	137.252
GO.Biological.Process	GO:0048008	platelet-derived.growth.factor.receptor.signaling.pathway	209	1.040020e-141	1.343394e-137	6.427722e-140	1.743314e+0	ABL1,ARID5B,BCAR1,BCR,CSRNP1,FER,IQGAP1,JAK2,MYO1E,NRP1,PDGFA,PDGFB,PDGFC,PDGFD,PDGFRB,PDGFRL,PIK3C2A,PLAT,PLEKHA1,PTEN,PTPN1,PTPN11,PTPRJ,RAPGEF1,RGS14,SGPL1,SRC,TIPARP,TXNIP,VEGFA,ZFAND5	TetrapodAncestor	136.872
GO.Biological.Process	GO:1901699	cellular.response.to.nitrogen.compound	210	4.288165e-141	5.539023e-137	2.637630e-139	1.180041e+0	AANAT,ABCB4,ABL1,ACTR2,ADAR,ADCY2,ADCY3,ADCY4,ADCY5,ADCY8,ADIPOQ,ADRB2,AGO1,AGO2,AGO3,AGO4,AGRN,AGT,AGTR1,AGTR2,AGTRAP,AHCYL1,AIF1,AIFM1,AKAP6,AKR1B1,AKT2,AOC1,AP3S1,APC,APEX1,APLP1,APOBEC1,APP,APPL1,AQP1,AQP8,ARG1,ARHGEF2,ARID1B,ATF4,ATP2B4,ATP6AP1,ATP6V0A4,ATP6V0B,ATP6V0C,ATP6V0D1,ATP6V0D2,ATP6V0E1,ATP6V0E2,ATP6V1B1,ATP6V1B2,ATP6V1C1,ATP6V1C2,ATP6V1D,ATP6V1E1,ATP6V1E2,ATP6V1G1,ATP6V1G3,ATP6V1H,BAD,BAIAP2L2,BCAR1,BCL11A,BCL2L1,BRCA1,BRIP1,C2CD5,CA2,CACNA1A,CACNA1S,CACNA2D1,CACNB1,CAMK2A,CAPN10,CAPN2,CASP3,CASP4,CASP6,CASQ2,CASR,CASTOR1,CAV1,CAV2,CAV3,CCL2,CCNA2,CD36,CDC5L,CDC6,CDH1,CDK2,CDK4,CDK5,CDK5R1,CEBPB,CFLAR,CFTR,CHRM1,CHRM2,CHRM3,CHRM4,CHRM5,CHRNA3,CHRNB2,CIB2,COL16A1,COL1A1,COL1A2,COL3A1,COL5A2,COL6A1,COLEC12,CPEB1,CPEB2,CPEB4,CPS1,CREB1,CRHBP,CRHR1,CRHR2,CRK,CSH1,CSK,CTNNA1,CTNNB1,CYBA,CYBB,CYFIP1,DAXX,DDC,DDX11,DDX58,DENND4C,DHX9,DIAPH1,DMTN,DNM2,DNMT3A,DPEP1,DRD1,DRD5,DROSHA,EDN1,EEF2K,EGFR,EGR1,EIF4EBP1,ENPP1,ENSG00000278139,EPHA4,ERRFI1,EZH2,EZR,FDX1,FER,FGF21,FIS1,FLOT1,FMR1,FOXC2,FOXO1,FOXO4,GAB1,GABPA,GABRB1,GABRB2,GABRB3,GABRG2,GCGR,GCK,GCLM,GH1,GH2,GHR,GHRHR,GHSR,GLP1R,GLP2R,GLRA1,GLRA2,GNA11,GNA15,GNAQ,GNB2,GNG10,GNG11,GNG12,GNG13,GNG2,GNG3,GNG7,GNG8,GNRHR,GOT1,GPD1,GPER1,GPLD1,GRB2,GRK2,GRM5,GSK3A,GSTM2,GSTP1,GUCY1B3,HCN1,HCN2,HCN3,HCN4,HDAC2,HDAC5,HDAC8,HDAC9,HNRNPA2B1,HNRNPD,HSF1,HSP90B1,HSPA5,HTR1B,ID1,IDE,IFIT1,IFNB1,IGF1,IGF1R,IGF2,IGFBP5,IL6,INHBB,INPP5K,INS,IPO5,IRF3,IRS1,IRS2,IRS4,ITPR2,JAK2,JAK3,JUP,KAT2B,KCNC2,KCNE1,KCNJ11,KCNQ1,KDM1A,KL,KLF1,KLF10,KLF11,KLF15,KLF2,KLF3,KLF4,KLF5,LAMTOR2,LAMTOR3,LAMTOR4,LARP1,LARS,LIN28A,LIN28B,LPIN1,LRP1,LRRK2,LYN,LYPD1,MAP3K5,MAPK1,MAPK3,MAS1,MAX,MB21D1,MDM2,MEF2C,MEN1,METTL3,MGARP,MMP3,MSX1,MTOR,MUL1,NCBP1,NDEL1,NEURL1,NFKB1,NGFR,NKX6-1,NOD1,NOX4,NPM1,NR1H4,NR4A1,NR4A2,NR4A3,NSMCE3,NTRK1,NTRK2,OPA1,OPRM1,P2RX4,P2RX7,PAK1,PARP1,PCK1,PDE12,PDE2A,PDE3A,PDE4B,PDE4D,PDGFC,PDGFD,PDK2,PDPK1,PDXP,PENK,PHIP,PIK3C2A,PIK3CA,PIK3CG,PIK3R1,PIK3R2,PIK3R3,PKD2,PKLR,PKM,PLA2G1B,PLCB1,POR,PPARG,PPARGC1A,PPP1R9B,PQBP1,PRKAA1,PRKACA,PRKACG,PRKAR1A,PRKAR1B,PRKAR2B,PRKCD,PRKCI,PRKCZ,PRKDC,PRKN,PRKRA,PRL,PRLR,PSEN1,PTAFR,PTEN,PTK2,PTPN1,PTPN22,PTPRA,PXN,RAB13,RAB31,RAB8A,RAD51,RALB,RAP1A,RAP1B,RAPGEF1,RAPGEF2,RAPGEF3,RECQL5,RELA,RGS10,RGS8,RHOQ,RIOK3,RIPK2,RPE65,RPL23,RPTOR,RRAGA,RRAGD,RYR1,RYR2,RYR3,SESN2,SESN3,SFRP1,SH2B2,SH3BP4,SHC1,SHMT1,SIRT2,SLC25A33,SLC26A3,SLC2A8,SLC30A10,SLC34A1,SLC38A9,SLC5A5,SLC6A4,SLC8A1,SLC8A3,SLC9A1,SLIT2,SLURP2,SMAD2,SMARCC1,SNCA,SNIP1,SOCS1,SOCS2,SOCS7,SOD1,SOGA1,SORBS1,SOS1,SOX9,SP1,SPAAR,SPIDR,SPOUT1,SRC,SRD5A1,SREBF1,SRRT,SRSF5,STAR,STAT6,STC1,STXBP4,TAF1,TARBP2,TBC1D4,TCIRG1,TERT,TGFB1,TH,TIMELESS,TLR3,TLR4,TLR6,TMEM173,TNF,TP53,TRAF2,TREM2,TRIB3,TRIM71,TRPM2,TRPV1,TSHR,TSN,TSNAX,TUSC5,UBR1,UBR2,UCP2,UMODL1,USF1,VAMP2,WDTC1,WNT1,WNT10B,XBP1,XRN1,YWHAG,ZC3H7A,ZCCHC11,ZEB1,ZFP36L1,ZNF106	TetrapodAncestor	136.257
GO.Biological.Process	GO:0051271	negative.regulation.of.cellular.component.movement	211	1.346193e-140	1.738877e-136	8.241126e-139	1.241395e+0	ABHD2,ABHD6,ABR,ACTN1,ACTN4,ACVRL1,ADA,ADAM15,ADAMTS9,ADARB1,ADGRB1,ADGRG1,ADIPOQ,ADIPOR1,ADORA1,ADORA3,AGTR2,AIF1,ALOX15B,ANGPT2,ANGPT4,AP1AR,APEX1,APOD,APOE,APOH,ARAP3,ARHGAP4,ARHGDIB,ARID2,ARPIN,BCL2,BCR,BMP10,BMP5,BMPR1A,BRAF,BST2,C16orf45,C5,C5orf30,CALR,CCDC125,CCL2,CCL21,CCL28,CD300A,CDKN1B,CERS2,CHRD,CITED2,CLASP1,CLASP2,COL3A1,CORO1B,CRK,CSNK2B,CTNNA1,CX3CL1,CX3CR1,CXCL13,CYGB,CYP19A1,CYP1B1,DAB2IP,DACH1,DCN,DDT,DLC1,DLG5,DLL4,DPEP1,DPYSL3,DRD2,DUSP10,ENG,EPHA1,EPPIN,EPPIN-WFDC6,ERBB4,EVL,FAM60A,FBLN1,FGF2,FLCN,FRMD5,FUZ,GATA3,GDF2,GNRH1,GPR18,GREM1,GSTP1,HDAC5,HMGB1,HMOX1,HRG,IDH2,IFITM1,IGFBP5,IL24,IL33,IL4,KANK1,KCNE3,KLF4,KLRK1,KRIT1,KRT16,LDLRAD4,LRCH1,LRP1,MAGI2,MARVELD3,MCC,MCTP1,MEOX2,MIA3,MIF,MIIP,MMP28,MMRN2,MYOCD,NAV3,NBL1,NDRG4,NF1,NF2,NISCH,NOG,NOTCH1,NOV,NRG1,NRG3,NRP1,PADI2,PBLD,PDCD10,PFN2,PHLDB2,PIN1,PKHD1,PKP2,PLCB1,PLXNA3,PODN,PPARD,PPARG,PPARGC1A,PTEN,PTGER4,PTN,PTPN23,PTPRG,PTPRJ,PTPRK,PTPRM,PTPRO,PTPRR,PTPRU,RAP2A,RAP2B,RAP2C,RECK,RGCC,RGN,RIPOR2,RNF20,RNF41,ROBO1,RRAS,SCAI,SEMA3A,SEMA5A,SEMA6D,SEMG1,SEMG2,SFRP1,SFRP2,SLC9A3R1,SLIT2,SLURP1,SMAD7,SP100,SPOCK3,SPRED1,SRF,SRGAP1,SRGAP2,SRGAP2B,SRGAP2C,SRGAP3,STAP1,STARD13,STC1,STK24,STK26,STRAP,SYNJ2BP,TACSTD2,TBX5,TGFB1,THBS1,THY1,TIE1,TIMP1,TMEFF2,TMIGD3,TP53INP1,TRIB1,VASH1,VCL,WNT11,WNT3,WNT3A,WNT4,WNT5A,ZMYND8	TetrapodAncestor	135.76
GO.Biological.Process	GO:0000165	MAPK.cascade	212	2.087543e-140	2.696479e-136	1.271924e-138	1.232562e+0	ADORA2B,AGT,ANGPT1,ARAF,ARTN,AVP,BRAF,BRAP,BTC,BTRC,CALM1,CAMK2A,CAMK2B,CAMK2D,CAMK2G,CAMKK2,CASR,CCL11,CCL19,CCL2,CCL3,CCL5,CCM2,CCR5,CDC42EP5,CHUK,CRKL,CRYAB,CSF2RA,CSF2RB,CTSH,CUL1,CUL3,DAB2IP,DAXX,DBNL,DLG4,DOK5,DUSP6,DUSP7,DUSP9,EGF,EGFR,EPGN,ERBB2,ERBB4,ERCC6,EREG,ERN1,ERN2,FBXW11,FGF1,FGF10,FGF13,FGF16,FGF17,FGF18,FGF19,FGF2,FGF20,FGF22,FGF23,FGF3,FGF4,FGF6,FGF7,FGF9,FGFR1,FGFR2,FGFR3,FGFR4,FRS2,FRS3,GDNF,GFRA1,GFRA2,GFRA3,GFRA4,GPS1,GRB2,GRIN1,GRIN2A,GRIN2B,GRIN2C,GRIN2D,HACD3,HBEGF,HGF,HRAS,HSF1,HTR2B,IGF1,IKBKB,IKBKG,IL17RD,IL18,IL1B,IL2,IL2RB,IL2RG,IL31RA,IL3RA,IL5,IL5RA,INS,IQGAP3,IRAK1,IRAK4,IRS1,IRS2,ITGAV,ITPKB,JAK2,JAK3,KARS,KBTBD7,KITLG,KL,KRAS,KSR1,LAMTOR2,LAMTOR3,LAT,LGALS9,LRRK2,MAP2K2,MAP2K3,MAP2K4,MAP2K6,MAP2K7,MAP3K1,MAP3K10,MAP3K11,MAP3K12,MAP3K13,MAP3K14,MAP3K15,MAP3K2,MAP3K21,MAP3K3,MAP3K4,MAP3K5,MAP3K6,MAP3K7,MAP3K7CL,MAP3K8,MAP3K9,MAP4K1,MAP4K3,MAP4K4,MAPK1,MAPK10,MAPK11,MAPK13,MAPK14,MAPK15,MAPK3,MAPK4,MAPK6,MAPK8,MAPK8IP1,MAPK8IP3,MAPK9,MAPKAPK2,MAPKAPK3,MAPKAPK5,MEF2A,MEF2C,MEN1,MET,MINK1,MOS,MUL1,MYC,NCAM1,NEFL,NF1,NFKB1,NLK,NOD1,NPHS1,NRAS,NRG1,NRG2,NRG4,NRK,NRTN,OXTR,PABPN1,PAK3,PDGFA,PDGFB,PDGFRB,PEA15,PKN1,PLVAP,PPM1L,PPP5C,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PSPN,PTGER4,PTK2,PTK2B,PTPN1,PTPRA,RAF1,RANBP9,RAPGEF2,RASA1,RASA2,RASA3,RASAL1,RASAL2,RASAL3,RASGEF1A,RASGRF1,RASGRF2,RASGRP1,RASGRP4,RET,RHBDD3,RIPK1,RIPK2,ROR2,RPS27A,SCG2,SETX,SH2D3A,SH2D3C,SHC1,SHC2,SHC3,SOS1,SOX9,SPAG9,SPRED1,SPTB,SPTBN2,SPTBN5,STK24,STK26,SYK,SYNGAP1,TAB1,TAB2,TAB3,TAOK1,TAOK2,TEK,TGFB1,TMEM189-UBE2V1,TNF,TNFRSF19,TNFSF11,TNIK,TNIP2,TPR,TRAF6,TRIB1,UBC,UBE2N,WDR83,WNT5A,WNT7B,YWHAB,YWHAE,ZFP36,ZFP36L1,ZFP36L2	TetrapodAncestor	135.569
GO.Biological.Process	GO:0010810	regulation.of.cell-substrate.adhesion	213	2.483386e-140	3.207790e-136	1.506005e-138	1.295495e+0	ABI3BP,ABL1,ACER2,ACTN4,ACVRL1,ADAM15,AGR2,AJAP1,ALOX15,ANGPT2,AP1AR,APOA1,APOD,ARHGAP6,ARHGEF7,ARL2,ARPC2,ATXN3,BCAS3,BCL2,BCL6,BRAF,BST1,C1QBP,CALR,CAMSAP3,CARMIL1,CASK,CCDC80,CCL21,CCL28,CCR7,CD36,CDC42,CDH13,CDK6,CDKN2A,CIB1,CLASP1,CLASP2,COL16A1,COL1A1,COL26A1,COL8A1,CRK,CRKL,CSF1,CYR61,DAPK3,DDR1,DISC1,DLC1,DMP1,DMTN,DNM2,DOCK5,ECM2,EDIL3,EFNA5,EGFLAM,EMP2,EPB41L5,EPHA1,EPHA3,FBLN1,FERMT1,FGG,FLNA,FMN1,FN1,FOXF1,FZD4,FZD7,GCNT2,GPM6B,GREM1,HAS2,HRG,HSD17B12,IQGAP1,ITGA3,ITGA5,JAK2,KANK1,LGALS1,MACF1,MELTF,MEN1,MINK1,MMP14,MYADM,NDNF,NET1,NF1,NF2,NINJ1,NOTCH1,NPY2R,NRP1,OLFM4,ONECUT1,PDPN,PHLDB2,PIK3R1,PLAU,PLEKHA2,PLET1,PLG,PPM1F,PREX1,PRKCE,PRKCZ,PTEN,PTK2,PTK2B,PTN,PTPRJ,PTPRO,RAC1,RAC2,RAC3,RASA1,RCC2,RELL2,RHOD,ROCK2,RREB1,RSU1,S100A10,SDC4,SEMA3E,SFRP1,SLC9A1,SMOC2,SPOCK1,SPOCK2,SRC,TACSTD2,TBCD,TEK,THBS1,THY1,TRIOBP,UTRN,VEGFA,VEGFC,VIT,VTN,VWC2,WASHC2C,WNT1,WNT4	TetrapodAncestor	135.494
GO.Biological.Process	GO:0046578	regulation.of.Ras.protein.signal.transduction	214	3.202756e-140	4.137000e-136	1.933178e-138	1.296893e+0	ABCA1,ABL1,ABR,ABRA,ADGRG1,ADRA1A,AKAP13,ALS2,APOA1,APOC3,APOE,ARAP3,ARF6,ARFGEF2,ARFGEF3,ARHGAP35,ARHGAP42,ARHGAP44,ARHGDIA,ARHGDIB,ARHGEF1,ARHGEF10L,ARHGEF11,ARHGEF12,ARHGEF16,ARHGEF17,ARHGEF19,ARHGEF2,ARHGEF25,ARHGEF26,ARHGEF3,ARHGEF33,ARHGEF37,ARHGEF39,ARHGEF4,ARHGEF40,ARHGEF7,ARHGEF9,ARRB1,AUTS2,BCL6,BCR,CCDC125,COL3A1,CRK,CSF1,CUL3,CYTH1,CYTH2,CYTH3,CYTH4,DAB2IP,DENND1A,DENND4B,DGKI,DLC1,DNM2,DNMBP,DYNLT1,ECT2,ECT2L,ENSG00000268465,ENSG00000273167,EPHB2,EPO,EPS8L1,EPS8L2,F2R,F2RL1,F2RL3,FARP1,FBP1,FBXO8,FGD1,FGD2,FGD3,FGD4,FGD5,FGF10,FLCN,FLOT1,FOXM1,GBF1,GPR17,GPR18,GPR20,GPR35,GPR4,GPR55,GPR65,HRAS,IGF1,IQSEC2,IQSEC3,ITGA3,ITGB1,ITPKB,ITSN1,ITSN2,KALRN,KANK1,KCTD13,KITLG,KRAS,LPAR1,LPAR4,LPAR6,MADD,MAPKAP1,MCF2,MCF2L,MCF2L2,MET,MFN2,MMD2,MYO9B,NET1,NF1,NGEF,NGF,NOTCH1,NOTCH2,NRG1,NRP1,NTRK1,NUP62,OBSCN,OGT,P2RY10,P2RY8,PDGFRB,PLCE1,PLEKHG1,PLEKHG2,PLEKHG3,PLEKHG4,PLEKHG4B,PLEKHG5,PLEKHG6,PLEKHG7,PPP2CB,PREX1,PSD,PSD2,PSD3,PSD4,RAC1,RAF1,RALGPS1,RALGPS2,RAPGEF1,RASA1,RASA2,RASA3,RASA4B,RASAL1,RASAL2,RASAL3,RASGEF1A,RASGRF1,RASGRF2,RASGRP1,RASGRP4,RDX,RGL2,RIPOR2,RIT2,ROBO1,RTN4R,SCAI,SGSM3,SOS1,SPATA13,SPRY1,SPRY2,SQSTM1,STAMBP,STMN1,SYNGAP1,TGFB2,TIAM1,TIAM2,TIMP2,TNFAIP1,TRIO,VAV1,VAV2,VAV3	TetrapodAncestor	135.383
GO.Biological.Process	GO:0060284	regulation.of.cell.development	215	6.425425e-140	8.299721e-136	3.860336e-138	1.123956e+0	ABCC8,ABL1,ABL2,ACTN4,ACTR2,ADCYAP1,ADD1,ADGRA2,ADGRB3,ADGRG1,ADIPOQ,ADNP,ADRA2B,ADRA2C,AGT,AKAP13,AKAP6,ALKAL1,ANAPC2,ANKRD1,ANKRD27,AP1AR,APOA1,APOE,APP,ARC,ARF1,ARF6,ARHGAP35,ARHGAP4,ARHGAP44,ARHGDIA,ARHGEF2,ARHGEF7,ARNTL,ARPC2,ASAP1,ASCL1,ASCL2,ASPA,ASPM,ATOH1,ATP6AP1,ATP8A2,AURKA,AVIL,AXIN2,BAD,BCL11A,BCL11B,BCL2,BCL6,BDNF,BIN1,BMP10,BMP2,BMP4,BMP5,BMP6,BMP7,BMPR1A,BMPR2,BRAF,BRINP1,BRINP2,BRINP3,C16orf45,C1QBP,C21orf91,CALR,CAMK1,CAMK1D,CAMK2B,CAPRIN1,CAPRIN2,CARM1,CARMIL1,CASZ1,CAV3,CBFA2T2,CCDC88A,CCR2,CDC20,CDC42,CDH2,CDH4,CDH5,CDK1,CDK5,CDK5R1,CDK5RAP1,CDK5RAP2,CDKL5,CDON,CERS2,CFL1,CFLAR,CHD7,CHODL,CHRNA3,CHRNB2,CIB1,CLCF1,CLDN18,CLDN5,CNR1,CNTF,CNTN1,CNTN2,CNTN4,COBL,COL3A1,CPEB1,CPNE5,CPNE6,CRABP2,CREB1,CRK,CRKL,CRMP1,CRX,CSF1,CSMD3,CSNK1D,CSNK1E,CTDP1,CTDSP1,CTNNA1,CTNNB1,CTSZ,CTTN,CUL7,CUX1,CUX2,CX3CR1,CXCR4,CYFIP1,DAB1,DAB2IP,DBN1,DCC,DCT,DDX56,DGUOK,DISC1,DISP3,DIXDC1,DKK1,DLG5,DLL1,DLL3,DLL4,DMRTA2,DMTN,DNM1L,DNM2,DNMT3B,DOCK5,DPYSL2,DPYSL3,DRAXIN,DRD2,DRD3,DSCAM,DTX1,DUOXA1,DUSP10,DUSP15,DVL1,DYNLT1,ECT2,EDN1,EDNRB,EEF2K,EFNA1,EFNA5,EFNB2,EFNB3,EIF2AK4,EIF4E,EIF4ENIF1,ELL3,EMX1,ENSG00000260272,EOMES,EPHA3,EPHA4,EPHA7,EPHB2,EPHB3,EPO,ERBB4,ETV5,EYA1,EZH2,F2,FAM129B,FBLN1,FBXO22,FBXO31,FBXO38,FBXO7,FBXW8,FERD3L,FES,FEZ1,FEZF1,FGF13,FGF20,FGFR1,FGG,FKBP1B,FKBP4,FLNA,FLRT2,FMR1,FN1,FOXA1,FOXG1,FOXO6,FRMD7,FSTL4,FUOM,FZD3,G6PD,GAK,GAL,GATA2,GATA3,GDF5,GDF6,GDI1,GDPD5,GFAP,GJC2,GLI2,GLI3,GNRH1,GOLGA4,GPER1,GPR183,GPR37L1,GPR68,GPRC5B,GRID2,GRIN1,GSK3A,HAMP,HAP1,HAS2,HDAC2,HDAC4,HDAC9,HES1,HES3,HES5,HEY2,HEYL,HGF,HIF1A,HMG20A,HMG20B,HMGB2,HOOK3,HSPA5,ID1,ID2,ID4,IDH2,IFNG,IFRD1,IGF1,IGSF10,IKBKB,IL1B,IL1RAP,IL1RAPL1,IL2,IL5,IL6,IL6ST,INPP5J,INS,IQGAP1,ISL1,ISLR2,IST1,ITGA3,ITM2C,ITPKA,ITSN2,JAG1,KALRN,KANK1,KATNB1,KDM1A,KDM4C,KEL,KIAA0319,KIF13B,KIF20B,KLF4,L1CAM,LBX1,LGALS1,LIF,LIG4,LIMK1,LIN28A,LINGO1,LLPH,LMOD3,LMX1A,LPAR1,LPAR3,LRIG2,LRP1,LRP4,LRP8,LRRC4C,LRRC7,LRRK2,LSM1,LTK,LYN,LZTS1,LZTS3,MACF1,MAG,MAGI2,MAN2A1,MAP1B,MAP2,MAP4K4,MAPK6,MAPT,MARK2,MBD1,MCF2,MDM2,MEF2C,MEGF8,MEIS1,MELTF,METRN,MIB1,MMD,MMD2,MOB2,MTOR,MUL1,MYADM,MYB,MYCL,MYCN,MYF6,MYLK3,MYOD1,MYOG,NBL1,NCK1,NCOA1,NCS1,NDEL1,NDNF,NDRG4,NEDD4L,NEFL,NEGR1,NEPRO,NET1,NEURL1,NEUROD1,NEUROG1,NEUROG3,NF1,NF2,NFATC4,NGEF,NGF,NGFR,NIPBL,NKX2-5,NKX6-1,NLGN1,NLGN3,NME1,NME2,NOG,NOS1,NOTCH1,NOTCH3,NPPC,NPR2,NPTN,NRG1,NRG3,NRP1,NTF3,NTF4,NTRK1,NTRK2,NTRK3,NUMB,NUMBL,OLFM1,OLFM4,OLIG2,OMG,OPA1,OPRM1,OSTN,PAEP,PAFAH1B1,PAK1,PAK3,PBX1,PCM1,PCP4,PDE3A,PDE5A,PDLIM5,PDPN,PER2,PHOX2B,PIN1,PLAA,PLAG1,PLK2,PLK5,PLPPR5,PLXNA1,PLXNA2,PLXNA3,PLXNA4,PLXNB1,PLXNB2,PLXNC1,PLXND1,PMP22,POU3F2,POU4F1,PPARG,PPP2R5B,PPP3CA,PQBP1,PREX1,PRKCH,PRKCI,PRKD1,PRKN,PRMT5,PROC,PROX1,PRPF19,PRRX1,PRUNE1,PSEN1,PTEN,PTK2,PTK2B,PTK7,PTN,PTPRD,PTPRG,PTPRO,PTPRS,PTPRZ1,RAB17,RAB21,RAB29,RAC1,RAC3,RAP1A,RAP1GAP2,RAP2A,RAPGEF1,RAPGEF2,RARA,RARB,RASAL1,RCC2,RELA,RELN,REST,RET,RFLNA,RFLNB,RFX3,RGMA,RGS14,RHEB,RIMS1,RIT2,RND2,RNF10,RNF6,ROBO1,ROBO2,ROCK2,RREB1,RRN3,RTN4,RTN4IP1,RTN4R,RTN4RL2,RUFY3,S100A10,S1PR3,S1PR5,SARM1,SCARB2,SCN1B,SCRT1,SCRT2,SDC2,SDK1,SEMA3A,SEMA3C,SEMA3G,SEMA4D,SEMA5A,SEMA6A,SEMA7A,SERPINE2,SERPINI1,SETX,SF3A2,SFRP1,SFRP2,SHANK1,SHB,SHOX2,SIGLEC15,SIPA1L1,SIRT2,SKI,SKIL,SLC39A12,SLC45A3,SLC6A4,SLC9B2,SLIT2,SLITRK1,SMAD4,SMO,SMURF1,SNAP25,SNAPIN,SNW1,SOCS2,SORL1,SOX10,SOX11,SOX14,SOX2,SOX3,SOX8,SOX9,SPAG9,SPEN,SPINT1,SPOCK1,SPP1,SRCIN1,SRF,SRGAP2,SRGAP2C,SRRT,SSH2,SSH3,STAP1,STAR,STK24,STMN2,STX1B,SYNGAP1,SYT1,SYT17,SYT2,SYT4,TACSTD2,TBX6,TCF3,TCF4,TENM3,TENM4,TERT,TGFB1,TGIF2,THOC2,THY1,TIAM1,TIMP2,TJP2,TLE6,TLR2,TLX2,TLX3,TMEM106B,TNF,TNFRSF12A,TNFRSF1A,TNFRSF21,TNFRSF8,TNFSF11,TNIK,TNR,TP73,TRAK1,TRAK2,TRIB1,TRIM11,TRIM32,TRIOBP,TRPC5,TRPC6,TRPV1,TSPO,TTL,TTPA,TUBB2B,TWF2,UBE2V2,UBE3A,UFL1,ULK2,ULK4,UNC13A,UNC5D,UST,VEGFA,VEGFC,VIM,VLDLR,VWC2,VWC2L,WASHC2C,WDR1,WDR36,WEE2,WNT3,WNT3A,WNT5A,WNT7A,XK,XRCC2,XRCC5,YAP1,YTHDF2,YWHAG,YWHAH,ZEB1,ZFYVE27,ZHX2,ZMYND8,ZNF335,ZNF365,ZNF488,ZNF609,ZNF804A	TetrapodAncestor	135.081
GO.Biological.Process	GO:0051384	response.to.glucocorticoid	216	2.344330e-138	3.028171e-134	1.401931e-136	1.362591e+0	AANAT,ABCA3,ABCB4,ABCC2,ACSBG1,ADAM9,ADCYAP1,ADIPOQ,AGL,AGTR2,AGXT,AIF1,ALAD,ALDH3A1,ALPL,ANXA1,ANXA3,APOA2,AQP1,AREG,ARG1,ATP2B1,AVPR1A,BAD,BCHE,BCL2,BGLAP,BMP6,CALCR,CASP3,CASP9,CCL1,CCL2,CCND1,CDKN1A,CDO1,CFLAR,CLDN1,CPN1,CPS1,DDIT4,DNMT3B,DUSP1,EDN1,EGFR,EIF4E,EIF4EBP1,EPHX1,EPO,ERRFI1,FAS,FBXO32,FIBIN,FOS,FOSB,FOSL1,FOXO1,GBA,GHRHR,GHSR,GLB1,GOT1,GPR83,GSTP1,HEY1,HMGB1,HNMT,HNRNPU,HSD11B2,IFNB1,IGFBP2,IGFBP7,IL10,IL1RN,IL22,IL6,ISL1,KLF9,KRAS,MAOB,MDK,METTL21C,MSTN,MYOD1,NEFL,NPAS4,NR3C1,NTRK3,OXT,PAM,PAPPA,PCK2,PCNA,PDCD7,PFKFB1,PPARGC1B,PTAFR,PTPRU,REST,S100B,SCGB1A1,SLIT2,SLIT3,SMYD3,SRD5A1,SSTR2,SSTR3,SSTR4,SSTR5,STAR,STC1,TAT,TGFB1,TH,TNF,TPH2,TRIM63,TYMS,UBE2L3,UCN,UCN3,UCP3,UGT1A1,USP8,WNT7B,ZFP36,ZFP36L1,ZFP36L2	TetrapodAncestor	133.519
GO.Biological.Process	GO:0043502	regulation.of.muscle.adaptation	217	7.532420e-138	9.729627e-134	4.483699e-136	1.485511e+0	AGT,AIF1,AKAP13,AKAP6,ATP2B4,BMP10,CAMK2B,CAMK2D,CAMK2G,CASQ1,CAV3,CDK9,CTDP1,EDN1,ERRFI1,FBXO32,FOXO1,G6PD,GLRX3,GSK3A,GTF2I,GTF2IRD1,HAMP,HAND2,HDAC4,IGF1,IGFBP5,IL6ST,JARID2,KLF4,LMCD1,LMNA,MEF2A,MLIP,MTMR4,MTOR,MTPN,MYH7,MYOG,NOL3,NOS3,NR4A3,P2RX4,PAK1,PARP1,PDE5A,PDE9A,PIN1,PPARGC1A,PPP3CA,PRKCA,RGS2,SCN5A,SLC9A1,SMAD4,TNNC1,TNNT1,TRIM63,TRPC3,TWF1,UTRN	TetrapodAncestor	133.012
GO.Biological.Process	GO:0010469	regulation.of.receptor.activity	218	2.296489e-137	2.966375e-133	1.360722e-135	1.195387e+0	ADA2,ADCYAP1,ADIPOQ,ADM2,ADORA1,ADRA2A,ADRA2B,ADRA2C,ADRB2,AGER,AGRP,AGT,AKAP6,ALG10B,AMELX,AMH,ANGPTL8,APELA,APLN,APP,ARC,AREG,ARTN,AVP,BDNF,BICD1,BMP1,BMP10,BMP15,BMP2,BMP4,BMP5,BMP6,BMP7,BMP8A,BMP8B,BTC,BUD31,C10orf99,C1QTNF12,C1QTNF4,C1QTNF9,CACNG2,CACNG3,CACNG5,CACNG7,CACNG8,CALM1,CALM2,CALM3,CAMK2D,CARTPT,CASQ2,CAV1,CAV3,CBL,CBLB,CBLC,CCK,CCL1,CCL11,CCL13,CCL14,CCL15,CCL15-CCL14,CCL16,CCL17,CCL18,CCL19,CCL2,CCL21,CCL22,CCL23,CCL27,CCL28,CCL3,CCL3L3,CCL4,CCL4L2,CCL5,CCL7,CCL8,CD320,CD70,CDC42EP2,CDK5,CDNF,CER1,CFTR,CGA,CGB1,CGB2,CGB3,CGB5,CGB7,CGB8,CHGB,CHMP6,CKLF,CLCF1,CLEC11A,CLEC12B,CMTM1,CMTM2,CMTM3,CMTM4,CMTM5,CMTM6,CMTM7,CMTM8,CNIH3,CNTF,COPA,CORT,CRHBP,CSF1,CSF3,CSH1,CSH2,CSHL1,CTF1,CTGF,CX3CL1,CXCL1,CXCL10,CXCL11,CXCL13,CXCL14,CXCL16,CXCL2,CXCL3,CXCL5,CXCL6,CXCL8,CXCL9,DAND5,DAPK1,DKK1,DLG4,DMD,EBI3,EDN1,EDN2,EDN3,EFEMP1,EGF,ENDOU,ENSG00000283663,ENSG00000284505,EPGN,EPHB2,EPO,EREG,ERFE,ERRFI1,F2,FAM3B,FAM3C,FAM3D,FASLG,FBXW7,FGF1,FGF10,FGF12,FGF13,FGF14,FGF16,FGF17,FGF18,FGF19,FGF2,FGF20,FGF21,FGF22,FGF23,FGF3,FGF4,FGF6,FGF7,FGF9,FKBP1A,FKBP1B,FLT3LG,FNDC5,FNTA,FOXH1,FSHB,GAL,GAS6,GAST,GDF1,GDF10,GDF11,GDF2,GDF3,GDF5,GDF6,GDNF,GFER,GH1,GH2,GHRH,GIP,GMFB,GMFG,GNRH1,GNRH2,GPHA2,GPHB5,GPNMB,GPRC5A,GREM1,GRN,GRP,GSTM2,HAMP,HAP1,HBEGF,HDGF,HDGFL3,HEYL,HGF,HMGB1,HRC,HTT,IAPP,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNB1,IFNE,IFNG,IFNK,IFNL1,IFNL2,IFNL3,IFNW1,IGF1,IGF2,IL12A,IL12B,IL13,IL15,IL16,IL17A,IL17B,IL17C,IL17F,IL18,IL19,IL1A,IL1B,IL1F10,IL1RN,IL2,IL20,IL21,IL22,IL23A,IL24,IL26,IL27,IL32,IL33,IL34,IL36A,IL36B,IL36G,IL36RN,IL37,IL4,IL5,IL6,IL7,IL9,INHA,INHBA,INHBB,INS,INS-IGF2,INSL3,INSL4,INSL5,INSL6,JAG1,JAG2,JPH1,JPH2,JPH3,JPH4,JSRP1,KCNE2,KCNK3,KITLG,KL,KLHL24,LACRT,LEFTY1,LEFTY2,LEP,LHB,LIF,LTB,LYPD1,LYPD6,LYPD6B,MACC1,MANF,MAPT,MDK,MED13,MEF2C,METRNL,MIA,MIF,MINK1,MLN,MSTN,NAMPT,NBL1,NCF1,NCK2,NCOA3,NDP,NENF,NETO1,NEURL1,NGF,NLGN1,NLGN3,NOS1,NOV,NPFF,NPPC,NPY,NRG1,NRG2,NRG3,NRG4,NRTN,NTF3,NTF4,NTS,NUDT6,OGN,OPRM1,OSGIN1,OSGIN2,OSM,OSTN,OXT,P2RY1,PARK7,PATE1,PATE4,PDE4D,PDGFA,PDGFB,PDGFC,PDGFD,PDYN,PENK,PF4,PF4V1,PKD2,PLAU,PLN,PMCH,PNOC,POMC,PPARGC1A,PPARGC1B,PPBP,PPP2R5B,PPY,PRKACA,PRKCD,PRKCE,PRL,PRLH,PROK1,PSCA,PSEN1,PSPN,PTEN,PTH,PTHLH,PTK2B,PTN,PYY,QRFP,RABEP1,RABEP2,RASGRF1,RELN,RETN,RETNLB,RLN1,RLN2,RLN3,RWDD1,SCG2,SCGB3A1,SCT,SECTM1,SELENON,SFRP2,SHANK1,SHC1,SHISA9,SLURP1,SLURP2,SNX6,SOCS4,SOCS5,SPP1,SPX,SRA1,SRI,SST,STC1,STC2,STOM,TAC4,TAF1,TDGF1,TFF1,TG,TGFB1,TGFB2,THBS4,THNSL2,THPO,TIMP1,TNF,TNFRSF11B,TNFSF10,TNFSF11,TNFSF12,TNFSF12-TNFSF13,TNFSF13,TNFSF13B,TNFSF14,TNFSF15,TNFSF18,TNFSF8,TNFSF9,TRDN,TSG101,TSHB,TSLP,TTR,TXLNA,TYMP,UBE2I,UCN,UCN3,UTS2,UTS2B,VEGFA,VEGFB,VEGFC,VEGFD,VIP,VPS25,VSTM1,WNT1,WNT10A,WNT10B,WNT3,WNT3A,WNT4,WNT5A,WNT7A,WNT7B,WNT8A,WNT8B,WNT9A,WNT9B,XCL1,XCL2,ZFYVE28,ZP3	TetrapodAncestor	132.528
GO.Biological.Process	GO:0007507	heart.development	219	3.081960e-137	3.980968e-133	1.817793e-135	1.169896e+0	ACVR2B,ACVRL1,ADAM15,ADAM19,ADAMTS1,ADAMTS9,ADAP2,ADGRG6,ADIPOR2,ADRA1A,AGT,AGTR2,AHI1,AKAP13,ANK2,ANKRD1,AP1B1,AP2B1,APELA,APLNR,ARID1A,ARID2,ARL13B,ASXL1,ATG5,ATM,AXIN2,BBS4,BBS7,BCOR,BICC1,BMP10,BMP2,BMP4,BMP5,BMP7,BMPR1A,BMPR2,BVES,C2CD3,C3orf58,C5orf42,CACNA1C,CACYBP,CALCRL,CALR,CASP3,CAV3,CBY1,CCDC103,CCDC40,CCM2,CCM2L,CCNB1,CDC42,CDK1,CER1,CHD7,CITED2,CLDN5,COL11A1,COL2A1,COL3A1,COL5A1,COX17,CRELD1,CRIP1,CRKL,CSRP3,CTNNB1,CXADR,CYR61,DAND5,DAW1,DCHS1,DCTN5,DHRS3,DLC1,DLL1,DLL4,DNAAF1,DNAH5,DNM2,DRC1,DSG2,DSP,DVL1,DYNC2H1,ECE2,EDN1,EFNA1,EGLN1,ENG,EOMES,EP300,EPHB4,EPOR,ERBB2,ERBB4,ERG,EYA1,FAT4,FGF12,FGF19,FGFR2,FGFRL1,FHL2,FHOD3,FKBP1A,FLRT2,FLRT3,FOXC1,FOXC2,FOXF1,FOXH1,FOXJ1,FOXL1,FOXN4,FREM2,FRS2,FZD1,FZD2,GAA,GALNT11,GATA3,GATA4,GATA6,GJA1,GJC1,GLI2,GLI3,GNA11,GNAQ,GPC3,GREM1,GRHL2,GRK2,GSK3A,GYS1,HAND1,HAND2,HAS2,HDAC9,HEG1,HES1,HEXIM1,HEY1,HEY2,HEYL,HHEX,HIF1A,HNRNPU,HSPB11,HTR2B,ID1,ID3,IFT140,IFT172,IFT20,IFT52,IFT57,IFT74,IHH,ISL1,ITGA3,ITGB1,JAG1,JMJD6,JUN,KCNAB1,KCNJ8,KCNK2,KDM6A,KDM6B,LBX1,LEFTY1,LEMD2,LMNA,LMO4,LOX,LRP6,LRRC10,LUZP1,MAML1,MAP2K4,MAPK1,MAPK3,MB,MBD1,MBD2,MBD3,MDM2,MEF2A,MEF2C,MEF2D,MEGF8,MESP1,MESP2,MIB1,MIXL1,MKKS,MSX1,MSX2,MTERF4,MTHFD1,MTOR,MYBPC3,MYH6,MYH7,MYL3,MYLK2,MYLK3,MYOCD,MYPN,NCOA6,NDRG4,NDST1,NEBL,NEK8,NF1,NFATC4,NIPBL,NKX2-5,NKX2-6,NKX3-1,NOG,NOTCH1,NOTCH2,NOTO,NOX4,NPHP3,NPRL3,NPY1R,NPY2R,NPY5R,NRG1,NRP1,NRP2,NSD2,NTRK3,OLFM1,OSR1,OVOL2,OXCT1,OXT,OXTR,PAM,PAX8,PCNA,PCSK5,PDGFB,PDGFRB,PDLIM3,PDLIM5,PITX2,PKD1,PKD2,PKP2,PLCE1,PLN,PLXND1,POU4F1,PPARA,PPARD,PPARG,PPP1R13L,PPP3CB,PRDM1,PRICKLE1,PRKAR1A,PRKDC,PROX1,PSEN1,PSKH1,PTCD2,PTCH1,PTEN,PTK2,PTK7,PTN,PTPN11,RAF1,RAMP2,RARA,RARB,RB1CC1,RBP4,RBPJ,REST,RIPPLY3,ROBO1,RTN4,RXRA,RYR1,RYR2,S1PR1,SCN5A,SCUBE1,SCX,SEC24B,SEMA3C,SETD2,SETDB2,SFRP2,SGCB,SGCD,SGCG,SGCZ,SHC1,SHOX2,SIK1,SIRT6,SLC8A1,SLC9A1,SMAD2,SMAD4,SMAD7,SMO,SMYD1,SMYD2,SNAI1,SNAI2,SNX17,SORBS2,SOS1,SOX11,SOX17,SOX18,SOX4,SOX9,SPRED1,SPRY1,SRF,SRI,STIL,STK4,STRA6,SUFU,T,TAB1,TAB2,TAZ,TBC1D32,TBX1,TBX2,TBX20,TBX3,TBX5,TCF25,TDGF1,TEAD2,TEK,TENM4,TFDP2,TGFB1,TGFB2,TGFBR1,TGFBR2,TH,TMED2,TMEM100,TMEM65,TNNC1,TNNI3,TNNT2,TRAF3IP1,TRIP11,TSC2,TTN,TWIST1,VANGL2,VEGFA,VEGFB,WNT11,WNT16,WNT3A,WNT5A,WNT8A,XIRP1,ZBTB14,ZDHHC16,ZFP36L1,ZFPM1,ZFPM2,ZIC3,ZMIZ1	TetrapodAncestor	132.4
GO.Biological.Process	GO:0071560	cellular.response.to.transforming.growth.factor.beta.stimulus	220	4.032227e-137	5.208428e-133	2.367467e-135	1.330081e+0	ACVRL1,ADAM9,AMHR2,ANKRD1,APAF1,ARG1,ARRB2,BAMBI,BMPR1A,CAV1,CBL,CCL2,CDH5,CGN,CITED1,CLDN1,CLDN5,CLEC3B,COL1A1,COL1A2,COL3A1,CREB1,CRK,CX3CR1,DUSP15,DUSP22,EDN1,EID2,EPB41L5,F11R,FERMT2,FGFR2,FKBP1A,FMOD,FNTA,FOS,FOXH1,FSHB,FURIN,FUT8,GCNT2,GDF10,GDF5,HDAC2,HIPK2,HPGD,ID1,ITGB5,JUN,KLF10,LEFTY1,LEFTY2,LTBP4,MAP3K7,MEF2C,MSTN,MTMR4,NEDD8,NLK,NOX4,NR3C1,PARD3,PARD6A,PARP1,PDCD5,PDE2A,PDE3A,PDGFB,PDGFD,PENK,PML,PPARGC1A,PRKCZ,PTK2,PTPRK,PXN,RPS27A,SCX,SFRP1,SKI,SKIL,SMAD2,SMAD4,SMAD5,SMAD7,SMURF1,SNRNP70,SOX5,SOX9,SRC,STAR,STK16,TAB1,TGFB1,TGFB2,TGFBR1,TGFBR2,TGFBRAP1,UBC,UBE2M,USP15,USP9X,USP9Y,WNT10A,WNT4,WNT5A,WNT7A,WWOX,XCL1,YES1,ZFP36L1,ZFP36L2,ZYX	TetrapodAncestor	132.283
GO.Biological.Process	GO:0003006	developmental.process.involved.in.reproduction	221	1.046941e-136	1.352334e-132	6.119157e-135	1.166415e+0	ABCB4,ABHD2,ACVR1B,ACVR2A,ADA,ADAD1,ADAM15,ADAMTS1,ADCYAP1,ADCYAP1R1,ADGRG1,AFP,AGO4,ALKBH1,ALOX15B,ALPL,AMH,AMHR2,ANGPT2,ANKRD7,ANXA1,AR,AREG,ARID1A,ARID4A,ARID5B,ARRB1,ARRB2,ASB1,ASCL2,ASH1L,ASPM,ATM,AURKC,AXL,B4GALT1,BAK1,BASP1,BAX,BBS4,BCL2,BCL2L1,BCL2L11,BCL2L2,BCL2L2-PABPN1,BIK,BIRC2,BIRC6,BMP15,BMP4,BMP5,BMP6,BMP7,BMPR1A,BMPR1B,BMPR2,BRIP1,BSG,CABYR,CAPZA3,CASP2,CASP5,CASP8,CATSPER4,CATSPERB,CATSPERD,CATSPERZ,CBL,CBX2,CCDC136,CCDC155,CCDC182,CCDC42,CCNB1,CCNB1IP1,CCND1,CCNF,CCR6,CDC25B,CDKL2,CDKN1B,CDKN1C,CDYL,CEBPA,CEBPB,CELF1,CELF4,CEP57,CFAP157,CFTR,CHD5,CHD7,CIB1,CITED1,CITED2,CNTFR,COL9A3,CRIP1,CSDE1,CSF1,CTNNA1,CTNNB1,CTSB,CUL7,CYP17A1,CYP19A1,CYP27B1,CYR61,DACH1,DACH2,DAZL,DCANP1,DCN,DDX25,DEAF1,DHCR24,DIAPH2,DLD,DLG1,DLX3,DMC1,DMRT1,DMRTA1,DNAH1,DNAJB6,DND1,DPY19L2,E2F7,E2F8,EGFR,EGLN1,EIF2B4,EIF2B5,EIF2S2,EOMES,EPAS1,EPOR,ERCC1,EREG,ESR1,ETNK2,ETV5,FABP9,FANCA,FANCC,FANCF,FANCG,FBXO5,FBXW8,FEM1B,FGF10,FGF9,FGFR2,FKBP4,FMN2,FNDC3A,FOSL1,FOXA1,FOXC1,FOXF2,FRS2,FSCN3,FSHB,FSHR,FSTL3,FZD4,FZD5,GALNTL5,GATA2,GATA3,GATA4,GATA6,GCM2,GGNBP2,GHSR,GJA1,GJB3,GJB5,GLI2,GLI3,GNRH1,GPR149,GRB2,GRHL2,H3F3A,HAND1,HES1,HEY1,HEY2,HIF1A,HMGB2,HMGCS1,HNF4A,HOOK1,HS6ST1,HSD17B2,HSD17B3,HSD17B4,HSF1,HSP90AB1,HSPA2,HTRA1,ICA1L,ID4,IGF2,IHH,IL10,IL1A,IL1B,IMMP2L,ING2,INHA,INHBA,INHBB,INSL6,INSRR,IQCF1,IRF2BPL,ITGB8,JAM3,JUNB,KDM3A,KDM5A,KDM5B,KIF18A,KISS1,KITLG,KLHL32,KMT2B,KNL1,KRT19,LDOC1,LEF1,LEP,LFNG,LGR4,LGR5,LHB,LHCGR,LHX1,LHX4,LHX8,LIF,LIN28A,LRP6,LRRC6,MAMLD1,MAP3K4,MAPK1,MAPK14,MARF1,MAS1,MAST2,MC2R,MDFI,MEA1,MEI1,MEI4,MEIOC,MEN1,MERTK,MGST1,MKKS,MLH1,MMP14,MMP19,MOV10L1,MSH2,MSH4,MTOR,MYOCD,NANOS3,NASP,NCOA1,NCOA4,NDP,NECTIN2,NECTIN3,NEURL1,NEUROG1,NIPBL,NKX3-1,NME5,NOBOX,NOG,NOS3,NOTCH1,NPHP1,NPM2,NR0B1,NRIP1,NSDHL,NSUN2,NTRK1,NUDT1,NUP107,NUP210L,NUPR1,OCA2,ODF2,OSBP2,OSR1,OVOL2,PABPC1L,PACRG,PAFAH1B1,PANK2,PAQR5,PAQR7,PAQR8,PATZ1,PBX1,PCDH12,PCSK4,PCYT1B,PDE3A,PDGFB,PDGFRB,PDILT,PGR,PHLDA2,PITX2,PIWIL2,PKD1,PKD2,PLA2G3,PLAC1,PLAG1,PLCD3,PLD6,PLEKHA1,PLG,PLK4,POMZP3,PPARD,PPARG,PRDM1,PRDX3,PRDX4,PRKACA,PRKACG,PRKDC,PRM2,PRSS42,PSAP,PSAPL1,PTCH1,PTCHD3,PTEN,PTGDR,PTGIS,PTK2,PTK2B,PTPN11,PYGO2,QKI,RAB13,RAD21L1,RARA,RARG,RBP4,RBPJ,RDH10,REC8,REN,RFX2,RHBDD1,RHOBTB3,RNF17,RNF2,RNF38,RNF8,ROBO2,ROPN1,ROPN1L,ROR2,RPS6,RSPH1,RSPO3,RXFP2,RXRA,SAFB2,SCX,SEPT4,SERPINA5,SERPINB5,SERPINE2,SETD2,SFRP1,SFRP2,SGPL1,SIRT1,SIX5,SLC26A3,SLC26A8,SLIRP,SLIT2,SLIT3,SMAD4,SMAD5,SMARCA2,SMARCC1,SNAI1,SOCS3,SOD1,SOHLH1,SOX15,SOX3,SOX8,SOX9,SPACA1,SPAG16,SPAG6,SPANXB1,SPINK1,SPINT1,SPO11,SPP1,SRC,SRD5A1,SRD5A2,SRPK1,ST14,STAR,STC1,STC2,STK4,STOX2,STRA6,STRA8,STRBP,STXBP1,SYCP1,SYCP2,TAF4,TAF4B,TARBP2,TBC1D20,TBPL1,TBX3,TCF21,TDRD5,TESC,TEX11,TEX15,TFAP2C,TFEB,TGFB1,TGFB2,TGFBR1,TIAL1,TIFAB,TIPARP,TLR3,TLR5,TMED2,TNC,TNFSF10,TNP1,TNP2,TOPAZ1,TP63,TPGS1,TRIM28,TRIP13,TSPY2,TSSK1B,TSSK2,TTC26,TTLL1,TTPA,TXNDC8,TYRO3,UBE2J1,UBE3A,VASH1,VASH2,VDR,VEGFA,WASHC5,WDR77,WNT4,WNT5A,WNT7A,WNT7B,WNT9B,YBX3,YTHDF2,ZBTB16,ZFAT,ZFP36L1,ZFP42,ZFPM2,ZMYND15,ZNF830,ZP3,ZPBP2	TetrapodAncestor	131.869
GO.Biological.Process	GO:0010594	regulation.of.endothelial.cell.migration	222	2.552640e-136	3.297245e-132	1.485246e-134	1.329693e+0	AAMP,ABL1,ACVRL1,ADAMTS9,ADGRA2,ADGRB1,AGT,AGTR2,AMOTL1,ANGPT1,ANGPT2,ANGPT4,ANXA3,APOE,APOH,ATOH8,ATP5A1,BCAR1,BCAS3,BMP10,BMP4,BMPER,BMPR2,CALR,CCBE1,CD40,CIB1,CSNK2B,CXCL13,DAB2IP,DCN,DLL4,EDN1,EFNA1,EMP2,EPHA2,ETS1,FGF1,FGF16,FGF18,FGF2,FGF4,FGFR1,FLT4,FOXC2,GATA3,GDF2,GPLD1,HDAC5,HDAC7,HDAC9,HIF1A,HMGB1,HRG,HSPB1,JCAD,KLF4,KRIT1,MEOX2,MET,MMRN2,NF1,NOTCH1,NRP1,NRP2,P2RX4,PDCD10,PDCD6,PDGFB,PDPK1,PLCG1,PLPP3,PPARG,PRCP,PRKCA,PRKD1,PRKD2,PROX1,PTK2,PTK2B,PTPRM,RGCC,ROCK2,SASH1,SCARB1,SEMA4A,SEMA5A,SH3BP1,SLIT2,SP100,SPRED1,SRPX2,STARD13,STC1,SYNJ2BP,TDGF1,TEK,TGFB1,THBS1,VASH1,VEGFA,VEGFC,WNT5A,WNT7A,ZC3H12A,ZNF580	TetrapodAncestor	131.482
GO.Biological.Process	GO:1901653	cellular.response.to.peptide	223	7.094949e-136	9.164546e-132	4.109662e-134	1.261582e+0	ADCY2,ADCY3,ADCY4,ADCY5,ADCY8,ADIPOQ,ADRB2,AGT,AGTR1,AGTR2,AGTRAP,AHCYL1,AKR1B1,AKT2,AP3S1,APC,APEX1,APOBEC1,APP,APPL1,ARG1,ARHGEF2,ARID1B,ATP6AP1,ATP6V0A4,ATP6V0B,ATP6V0C,ATP6V0D1,ATP6V0D2,ATP6V0E1,ATP6V0E2,ATP6V1B1,ATP6V1B2,ATP6V1C1,ATP6V1C2,ATP6V1D,ATP6V1E1,ATP6V1E2,ATP6V1G1,ATP6V1G3,ATP6V1H,BAIAP2L2,BCAR1,BRIP1,C2CD5,CA2,CACNA1A,CACNA2D1,CACNB1,CAMK2A,CAPN10,CASP4,CASR,CAV1,CAV2,CCL2,CCNA2,CD36,CDC5L,CDC6,CDK4,CDK5,CFLAR,CPEB1,CPEB2,CPS1,CREB1,CRHBP,CRHR1,CRHR2,CRK,CSH1,CSK,CYBA,CYFIP1,DDX11,DENND4C,EDN1,EEF2K,EIF4EBP1,ENPP1,ENSG00000278139,EPHA4,ERRFI1,FER,FGF21,FIS1,FOXC2,FOXO1,FOXO4,GAB1,GCGR,GCK,GH1,GH2,GHR,GHRHR,GHSR,GLP1R,GLP2R,GNB2,GNG10,GNG11,GNG12,GNG13,GNG2,GNG3,GNG7,GNG8,GNRHR,GOT1,GPER1,GPLD1,GRB2,GRM5,GSK3A,GSTP1,HDAC5,HDAC9,HSF1,ID1,IDE,IGF1,IGF1R,IGF2,IL6,INHBB,INPP5K,INS,IRS1,IRS2,IRS4,JAK2,JAK3,KAT2B,KL,KLF1,KLF10,KLF11,KLF15,KLF2,KLF3,KLF4,KLF5,LPIN1,LRP1,LYN,MAPK1,MAPK3,MAS1,MAX,MDM2,MEN1,MGARP,NDEL1,NFKB1,NGFR,NKX6-1,NOD1,NR4A1,NR4A2,NR4A3,PAK1,PARP1,PCK1,PDK2,PDPK1,PHIP,PIK3C2A,PIK3CA,PIK3R1,PIK3R2,PIK3R3,PKLR,PKM,PLA2G1B,POR,PPARG,PRKACA,PRKACG,PRKAR1A,PRKAR1B,PRKAR2B,PRKCD,PRKCI,PRKCZ,PRKDC,PRL,PRLR,PSEN1,PTEN,PTK2,PTPN1,PTPN22,PTPRA,PXN,RAB13,RAB31,RAB8A,RAP1B,RELA,RHOQ,RIPK2,RPE65,RPL23,SH2B2,SHC1,SLC25A33,SLC2A8,SLC30A10,SLC9A1,SMARCC1,SOCS2,SOCS7,SOGA1,SORBS1,SOS1,SP1,SRC,SRD5A1,SREBF1,SRSF5,STAR,STXBP4,TBC1D4,TCIRG1,TGFB1,TIMELESS,TLR4,TLR6,TP53,TRIB3,TSHR,TUSC5,UCP2,UMODL1,USF1,VAMP2,WDTC1,WNT1,XBP1,YWHAG,ZFP36L1,ZNF106	TetrapodAncestor	131.038
GO.Biological.Process	GO:0010948	negative.regulation.of.cell.cycle.process	224	1.127876e-135	1.456877e-131	6.503917e-134	1.295250e+0	APAF1,APC,ATF5,ATM,AURKA,AURKAIP1,AURKB,BAX,BCL2,BCL6,BMI1,BMP4,BMP7,BRCA1,BTG2,BUB1,C10orf99,CALR,CARM1,CASP2,CBX3,CCNB1,CCND1,CCNF,CCNK,CDC25C,CDC73,CDK1,CDK2,CDK2AP2,CDK4,CDK5RAP2,CDK9,CDKN1A,CDKN1B,CDKN2B,CDKN2D,CENPF,CENPJ,CHEK1,CHEK2,CHMP2A,CHMP4C,CNOT1,CNOT10,CNOT11,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT8,CRADD,CTDSP1,CTDSP2,CTDSPL,CUL1,DAB2IP,DACT1,DCUN1D3,DMRT1,DONSON,E2F1,E2F4,E2F6,E2F7,E2F8,EED,EP300,EPC1,ESPL1,EZH2,FANCI,FBXL7,FBXO31,FBXO5,FBXO7,FBXW7,FGF10,FOXE3,FOXN3,FOXO4,FZD9,GADD45A,GIGYF2,GJC2,GML,GPER1,GPNMB,GPR132,GTSE1,H2AFY,HMGA2,HMGN5,HSP90AB1,HUS1,HUS1B,IK,JADE1,KANK2,KIF25,KLHL22,L3MBTL2,LIF,MAD1L1,MAD2L1,MAD2L2,MAX,MDM1,MDM2,MDM4,MEN1,MGA,MIF,MIIP,MLXIPL,MOS,MRE11,MRNIP,MSH2,MTBP,MUC1,MUS81,MYO16,NAA10,NAE1,NANOS2,NBN,NOP53,NPM1,NUBP1,NUPR2,ORAOV1,OSM,OVOL1,PCBP4,PCGF2,PCNA,PHC1,PHC3,PHOX2B,PIDD1,PINX1,PKD2,PLAGL1,PLK1,PLK2,PLK3,PML,PPP2R5B,PRKAR1A,PRKDC,PRMT1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTEN,PTTG1,PTTG2,RAD1,RAD17,RAD21,RAD51,RB1,RBBP4,RBBP7,RBBP8,RBM14,RFWD3,RGCC,RING1,RNF2,RPA2,RPL23,RPS27A,RPS27L,RRM2,RYBP,SETMAR,SFN,SLFN11,SMARCA4,SMC1A,SOX4,STAG2,SUSD2,TERF1,TERF2,TEX14,TFDP2,TICRR,TMEM67,TNKS,TNKS1BP1,TOM1L1,TOPBP1,TP53,TP63,TP73,TPR,TPRA1,TRIAP1,TRIM37,TRIP13,TTK,UBC,USP47,UXT,VPS4A,WAPL,YAF2,ZFP36L1,ZFP36L2,ZFYVE19,ZNF207,ZNF385A,ZNF830,ZW10	TetrapodAncestor	130.837
GO.Biological.Process	GO:0003206	cardiac.chamber.morphogenesis	225	1.280515e-135	1.654041e-131	7.351294e-134	1.310741e+0	ADAMTS1,ADGRG6,BMP10,BMP4,BMP5,BMP7,BMPR1A,BMPR2,CAV3,CCM2L,CHD7,CITED2,COL11A1,CYR61,DHRS3,DLL4,DSP,EGLN1,ENG,FGFR2,FGFRL1,FHL2,FKBP1A,FOXC1,FOXC2,FOXF1,FOXH1,FZD1,FZD2,GATA3,GATA4,GATA6,GRHL2,GSK3A,HAND1,HAND2,HEG1,HES1,HEY1,HEY2,HEYL,HIF1A,ISL1,JAG1,MDM2,MEF2C,MESP1,MSX2,MYBPC3,MYH6,MYH7,MYL3,NKX2-5,NOG,NOTCH1,NOTCH2,NPY2R,NPY5R,NRG1,NRP1,NRP2,NSD2,OVOL2,PITX2,PKP2,POU4F1,PPP1R13L,PROX1,PTCD2,RARA,RARB,RBP4,RBPJ,RXRA,RYR2,SEMA3C,SFRP2,SHOX2,SMAD4,SMAD7,SMO,SOS1,SOX11,SOX4,SRF,TBX1,TBX2,TBX20,TBX3,TBX5,TEK,TGFB1,TGFB2,TGFBR1,TGFBR2,TNNC1,TNNI3,TNNT2,VANGL2,WNT11,WNT5A,ZFPM1,ZFPM2	TetrapodAncestor	130.781
GO.Biological.Process	GO:0002757	immune.response-activating.signal.transduction	226	3.211119e-135	4.147802e-131	1.835311e-133	1.257639e+0	ABI1,ABL1,ACTR2,ACTR3,APOB,ARPC1A,ARPC1B,ARPC2,ARPC4,ARPC5,BAG6,BAX,BCAR1,BCL10,BCL2,BIRC2,BIRC3,BLK,BRAF,BTK,BTRC,C3AR1,CARD11,CASP8,CD14,CD180,CD19,CD209,CD247,CD28,CD300LF,CD36,CD38,CD3D,CD3E,CD3G,CD79B,CD86,CDC42,CHUK,CLEC4A,CLEC4C,CLEC4D,CLEC4E,CLEC6A,CLEC7A,CNPY3,COLEC12,CR1,CR2,CRK,CSK,CTLA4,CTSB,CTSL,CUL1,CYFIP1,CYFIP2,DDX58,DENND1B,DMBT1,ELMO1,ELMO2,ENSG00000173366,EP300,FADD,FBXW11,FCER1G,FCN1,FFAR2,FGG,FGR,FOXP3,FYB1,FYB2,GATA3,GPLD1,GPR32,GPR33,GRAP2,GRB2,HAVCR2,HCK,HMGB1,HRAS,HSP90AB1,HSP90B1,ICAM2,IFNG,IGLL1,IGLL5,IKBKB,IKBKE,IKBKG,INAVA,INPP5D,IRAK1,IRAK3,IRAK4,IRF3,IRF7,IRGM,ITCH,ITGAM,ITGB2,ITK,KLHL6,KLRK1,KRAS,LAT,LAT2,LAX1,LBP,LCK,LCP2,LGMN,LIMK1,LRRC70,LY96,LYN,MALT1,MAP2K6,MAP3K1,MAP3K7,MAPK1,MAPK3,MAPKAPK2,MAPKAPK3,MARCO,MEF2C,MUC1,MUC12,MUC13,MUC15,MUC20,MUC3A,MUC4,MUC5AC,MUC5B,MUC6,MUCL1,MYO10,MYO1C,MYO1G,NCK1,NCKAP1,NCKAP1L,NCR3,NFAM1,NFATC2,NFKB1,NOD1,NR1H4,NR4A3,NRAS,OTULIN,PAG1,PAK1,PAK2,PAK3,PDE4B,PDE4D,PDPK1,PGLYRP1,PGLYRP2,PGLYRP3,PGLYRP4,PIK3AP1,PIK3C3,PIK3CA,PIK3CD,PIK3R1,PIK3R2,PLA2G6,PLCG1,PLCG2,PLD2,PLEKHA1,PLPP4,PRKACA,PRKACG,PRKCB,PRKCD,PRKCE,PRKCQ,PRKD2,PSEN1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTK2,PTPN22,PTPRJ,RAC1,RAF1,RBCK1,REG3G,RELA,RELB,RFTN1,RFTN2,RIPK1,RIPK2,RNF31,RPS27A,RPS6KA3,RPS6KA5,S100A1,S100A14,S100A8,S100A9,SHB,SKAP2,SLA2,SNAI3,SPG21,SPPL3,SRC,SYK,TAB1,TAB2,TAB3,TBK1,TEC,THEMIS,THEMIS2,THY1,TICAM1,TICAM2,TIRAP,TLR1,TLR10,TLR2,TLR3,TLR4,TLR5,TLR6,TLR9,TMEM189-UBE2V1,TNFAIP3,TNFRSF21,TNIP1,TNIP2,TNIP3,TRAF3,TRAF6,TRAT1,TRIL,TRIM5,TXK,UBC,UBE2D1,UBE2D2,UBE2D3,UBE2N,UNC93B1,VAV1,VAV2,VAV3,WASF2,WIPF2,WIPF3,YES1,ZAP70	TetrapodAncestor	130.382
GO.Biological.Process	GO:0045639	positive.regulation.of.myeloid.cell.differentiation	227	3.729142e-135	4.816933e-131	2.121997e-133	1.484652e+0	ACIN1,ACVR1B,ACVR2A,ANKRD54,ATP6AP1,CA2,CASP8,CCR1,CD101,CD74,CREB1,CSF1,CSF3,ETS1,FADD,FAM210B,FES,FOS,GATA2,GNAS,GPR68,HAX1,HCLS1,HIF1A,HMGB1,HMGB2,IFNG,IL12B,IL17A,IL20,IL23A,IL23R,IL34,IL5,INHBA,INPP5D,ISG15,JAG1,JUN,KITLG,KLF10,LEF1,LEP,LIF,MAPK14,NCKAP1L,OCSTAMP,PF4,POU4F1,PPARGC1B,PRKCA,PRMT1,RAB7B,RB1,RIPK1,ROR2,RUNX1,SCIN,SLC9B2,SMAP1,STAT1,TAL1,TESC,THPO,TMEM64,TNF,TNFSF11,TRAF6,TRIB1,ZFP36L1,ZNF16	TetrapodAncestor	130.317
GO.Biological.Process	GO:0042035	regulation.of.cytokine.biosynthetic.process	228	1.337698e-134	1.727905e-130	7.578529e-133	1.499246e+0	APOA2,ASB1,BCL10,BCL3,CARD11,CCR2,CD276,CD28,CD3E,CD80,CD86,CEBPB,CEBPG,CYBB,EBI3,EGR1,EREG,ERRFI1,FOXJ1,FOXP3,GATA3,GHSR,HMOX1,HSPB1,IFNG,IGF2BP1,IGF2BP2,IGF2BP3,IL10,IL12B,IL17F,IL1A,IL1B,IL21,IL27,IL4,IL6,IL9,INHA,INHBA,INHBB,INPP5D,IRF1,IRF4,KLF4,LBP,LTB,MAP2K3,MAPKAPK2,MAST2,NFKB1,NMI,PRG2,PRG3,PRKCQ,PTAFR,RELA,RNF128,SIGIRR,SPN,SYK,TBK1,THBS1,TIA1,TICAM1,TIRAP,TLR1,TLR3,TLR4,TLR6,TLR9,TNF,TNFRSF13C,TNFRSF8,TRAF6,TRIB2,UBE2J1,WNT5A,ZFP36,ZFPM1	TetrapodAncestor	129.762
GO.Biological.Process	GO:0051056	regulation.of.small.GTPase.mediated.signal.transduction	229	2.230910e-134	2.881666e-130	1.258370e-132	1.234483e+0	A2M,ABCA1,ABL1,ABR,ABRA,ADCYAP1R1,ADGRG1,ADRA1A,AKAP13,ALS2,AMOT,APOA1,APOC3,APOE,ARAP1,ARAP2,ARAP3,ARF6,ARFGEF2,ARFGEF3,ARHGAP1,ARHGAP11A,ARHGAP12,ARHGAP15,ARHGAP17,ARHGAP18,ARHGAP19,ARHGAP20,ARHGAP21,ARHGAP22,ARHGAP23,ARHGAP24,ARHGAP25,ARHGAP26,ARHGAP28,ARHGAP29,ARHGAP30,ARHGAP31,ARHGAP32,ARHGAP33,ARHGAP35,ARHGAP39,ARHGAP4,ARHGAP42,ARHGAP44,ARHGAP5,ARHGAP6,ARHGAP8,ARHGDIA,ARHGDIB,ARHGEF1,ARHGEF10L,ARHGEF11,ARHGEF12,ARHGEF16,ARHGEF17,ARHGEF19,ARHGEF2,ARHGEF25,ARHGEF26,ARHGEF3,ARHGEF33,ARHGEF37,ARHGEF39,ARHGEF4,ARHGEF40,ARHGEF7,ARHGEF9,ARRB1,AUTS2,BCL6,BCR,CCDC125,CD2AP,CDC42,CDON,CHN2,COL3A1,CRK,CSF1,CUL3,CYTH1,CYTH2,CYTH3,CYTH4,DAB2IP,DENND1A,DENND4B,DEPDC1B,DGKI,DLC1,DNM2,DNMBP,DYNLT1,ECT2,ECT2L,ENSG00000268465,ENSG00000273167,EPHB2,EPO,EPS8L1,EPS8L2,F2R,F2RL1,F2RL3,FAM13A,FAM13B,FARP1,FBP1,FBXO8,FGD1,FGD2,FGD3,FGD4,FGD5,FGF10,FLCN,FLOT1,FOXM1,FRMD7,GARNL3,GBF1,GDI1,GDI2,GNA13,GPR17,GPR18,GPR20,GPR35,GPR4,GPR55,GPR65,HRAS,IGF1,INPP5B,IQSEC2,IQSEC3,ITGA3,ITGB1,ITPKB,ITSN1,ITSN2,KALRN,KANK1,KCTD13,KITLG,KRAS,LPAR1,LPAR4,LPAR6,MADD,MAPKAP1,MCF2,MCF2L,MCF2L2,MET,MFN2,MMD2,MYO9A,MYO9B,NET1,NF1,NGEF,NGF,NOTCH1,NOTCH2,NRG1,NRP1,NTRK1,NUP62,OBSCN,OCRL,OGT,OPHN1,P2RY10,P2RY8,PDGFRB,PIK3R2,PLCE1,PLEKHG1,PLEKHG2,PLEKHG3,PLEKHG4,PLEKHG4B,PLEKHG5,PLEKHG6,PLEKHG7,PPP2CB,PREX1,PSD,PSD2,PSD3,PSD4,RAC1,RAC2,RAC3,RACGAP1,RAF1,RALBP1,RALGAPB,RALGPS1,RALGPS2,RAP1GAP,RAP1GAP2,RAPGEF1,RASA1,RASA2,RASA3,RASA4B,RASAL1,RASAL2,RASAL3,RASGEF1A,RASGRF1,RASGRF2,RASGRP1,RASGRP4,RDX,RELN,RGL2,RHOBTB1,RHOBTB2,RHOC,RHOD,RHOG,RHOJ,RHOQ,RHOU,RHOV,RIPOR2,RIT2,ROBO1,RTN4R,SCAI,SGSM3,SH3BP1,SIPA1,SIPA1L1,SIPA1L2,SIPA1L3,SLIT2,SOS1,SPATA13,SPRY1,SPRY2,SQSTM1,SRC,SRGAP1,SRGAP2,SRGAP3,STAMBP,STARD13,STARD8,STMN1,SYDE1,SYDE2,SYNGAP1,TAGAP,TGFB2,TIAM1,TIAM2,TIMP2,TNFAIP1,TRIO,TRIP10,TSC2,VAV1,VAV2,VAV3	TetrapodAncestor	129.54
GO.Biological.Process	GO:0032944	regulation.of.mononuclear.cell.proliferation	230	2.472754e-134	3.194056e-130	1.388720e-132	1.314794e+0	ADA,AGER,AHR,AIF1,ANXA1,ARG1,ARG2,ATAD5,ATM,BCL2,BCL6,BMP4,BST1,BTK,CARD11,CASP3,CCDC88B,CCL19,CCL5,CCR2,CD1D,CD209,CD24,CD274,CD276,CD28,CD300A,CD320,CD38,CD3E,CD40,CD46,CD55,CD59,CD6,CD74,CD80,CD81,CD86,CDKN1A,CEBPB,CHRNB2,CLC,CLCF1,CLEC4G,CLECL1,CORO1A,CSF1,CTLA4,CTNNB1,DHPS,DLG1,DLG5,DNAJA3,EBI3,EFNB1,EPO,ERBB2,FADD,FGF10,FOXJ1,FOXP3,GAL,GNRH1,GPAM,GPNMB,GPR183,HAVCR2,HES1,HHLA2,HMGB1,IDO1,IFNG,IGF1,IGF2,IGFBP2,IHH,IKZF3,IL10,IL12A,IL12B,IL12RB1,IL13,IL15,IL18,IL1B,IL2,IL20RB,IL21,IL23A,IL23R,IL27,IL4,IL5,IL6,IL6ST,IL7,INPP5D,IRF1,IRS2,ITCH,JAK3,LEP,LGALS3,LGALS9,LILRB2,LRRC32,LST1,LYN,MAD1L1,MEF2C,MIF,MZB1,NCK1,NCK2,NCKAP1L,NDFIP1,NFATC2,PAWR,PDCD1LG2,PDE5A,PELI1,PKN1,PLA2G2D,PLA2G2F,PNP,PRDM1,PRKAR1A,PRKCQ,PTPN22,PYCARD,RAC2,RASAL3,RC3H1,RIPK2,RIPK3,RPS3,SASH3,SCGB1A1,SDC4,SELENOK,SLC39A10,SOS1,SOX11,SPN,SYK,TAC1,TFRC,TGFB1,TGFBR2,TICAM1,TIRAP,TLR4,TLR9,TMEM131L,TMIGD2,TNFRSF13B,TNFRSF13C,TNFRSF14,TNFRSF21,TNFRSF4,TNFSF13B,TNFSF18,TNFSF9,TRAF6,VAV3,VCAM1,VSIG4,VTCN1,WNT3A,XCL1,ZAP70,ZNF335,ZP3,ZP4	TetrapodAncestor	129.496
GO.Biological.Process	GO:0034614	cellular.response.to.reactive.oxygen.species	231	3.415115e-134	4.411304e-130	1.909655e-132	1.457651e+0	ABL1,ADPRHL2,AIFM1,AKR1B1,ANKZF1,ANXA1,APEX1,APOA4,AQP1,ARG1,AXL,BECN1,BNIP3,BTK,CAMKK2,CBX8,CCNA2,CDK1,CDK2,CFLAR,CHUK,CRK,CRYGD,CYP1B1,DNM2,DPEP1,ECT2,EGFR,ENSG00000256632,ERCC6L2,ETS1,EZH2,FABP1,FANCC,FER,FOS,FOXO1,FXN,GLRX2,GUCY1B3,HDAC2,HNRNPD,HSF1,IL18BP,IL18RAP,IL6,JUN,KCNC2,KDM6B,KLF2,KLF4,LCN2,MAP1LC3A,MAP3K5,MAPK1,MAPK3,MAPK8,MAPK9,MDM2,MMP3,MMP9,MPO,MPV17,MYB,NCF1,NET1,NME8,NOS3,NQO1,PARK7,PAX2,PCGF2,PCNA,PDCD10,PDGFD,PDK2,PKD2,PLEKHA1,PPARGC1B,PPIF,PPP5C,PRDX1,PRDX2,PRDX3,PRDX5,PRKAA1,PRKCD,PTPRK,PXN,RELA,ROMO1,RPS3,SETX,SIRT1,SOD1,SOD2,SOD3,SRC,STAT6,TNFAIP3,TRAF2,TRPC6,TRPM2,UCP1,ZNF277,ZNF580	TetrapodAncestor	129.355
GO.Biological.Process	GO:0006366	transcription.from.RNA.polymerase.II.promoter	232	1.890215e-133	2.441591e-129	1.052410e-131	1.145433e+0	ADRM1,AHR,AKNA,ALX1,ALX4,ALYREF,AR,ARID3B,ARID3C,ARID4A,ARNT2,ARNTL,ARRB1,ARRB2,ASH1L,ASH2L,ATF3,ATF4,ATF5,ATF6,ATF6B,ATOH1,BACH1,BACH2,BARHL1,BARX1,BARX2,BATF3,BAX,BCL11B,BHLHA15,BMPR2,CAMTA1,CAMTA2,CARF,CASC3,CBFB,CCNB1,CCND1,CCNH,CCNK,CCNT2,CDC40,CDC5L,CDC73,CDK1,CDK13,CDK4,CDK7,CDK9,CDKN1A,CDX1,CEBPA,CEBPB,CEBPD,CEBPE,CEBPG,CEBPZ,CHTOP,CLP1,COPS2,CPSF1,CPSF2,CPSF4,CPSF7,CREB1,CREB3,CREB3L1,CREB3L2,CREB3L3,CREB5,CREBRF,CRX,CSRNP1,CSTF1,CSTF2,CSTF2T,CTCF,CTCFL,CTDP1,CTGF,DACH1,DACH2,DBP,DDX21,DDX39A,DDX5,DEAF1,DEK,DHX38,DLX3,DLX5,DMRT1,DTX1,DVL1,E2F2,E2F3,E2F4,EAF1,EBF2,EBF3,ECD,EGR1,EGR2,EGR4,EHF,EIF4A3,ELF1,ELF3,ELF4,ELF5,ELK1,ELK3,ELK4,ELL2,ELL3,ELOA,ELOA2,ELOB,ELOC,ELOF1,ELP3,ENSG00000250782,ENSG00000284042,ENSG00000284552,EP300,EPAS1,ERCC2,ERCC3,ERCC6,ERG,ESR1,ESR2,ESRRA,ESRRB,ESRRG,ETS1,ETV1,ETV4,ETV5,ETV6,ETV7,FAM170A,FEV,FIP1L1,FLI1,FLNA,FOS,FOSB,FOSL1,FOSL2,FOXA1,FOXC1,FOXC2,FOXD2,FOXE3,FOXF1,FOXF2,FOXH1,FOXI1,FOXJ1,FOXJ2,FOXK2,FOXN1,FOXO4,FUBP3,GABPA,GATA2,GATA3,GATA4,GATA5,GATA6,GBX2,GCM2,GLI2,GLI3,GLIS1,GLIS3,GMEB1,GRHL2,GRHL3,GTF2A1,GTF2A1L,GTF2A2,GTF2E1,GTF2E2,GTF2F1,GTF2F2,GTF2H1,GTF2H2,GTF2H3,GTF2H4,GTF2H5,GTF2I,GTF2IRD1,HAND1,HAND2,HCFC1,HEYL,HIF1A,HIF3A,HIVEP1,HIVEP2,HIVEP3,HLF,HLTF,HMGA2,HNF1A,HNF4A,HNF4G,HNRNPK,HOXA1,HOXC13,HSF2,HSF2BP,ICE1,IKZF3,INTS10,INTS11,INTS13,INTS14,INTS3,INTS4,INTS5,INTS6,INTS8,INTS9,IRF1,IRF2,IRF3,IRF4,IRF6,IRF7,IRF9,ISL1,IWS1,JUN,JUNB,KAT2B,KDM5A,KLF10,KLF11,KLF13,KLF14,KLF15,KLF4,KLF5,KLF6,KLF7,LCORL,LEF1,LEO1,LHX1,LHX2,LHX4,LITAF,LMO2,LMO4,LMX1A,LSM11,MACC1,MAF,MAFA,MAFB,MAFF,MAFG,MAGOH,MAGOHB,MAML1,MAML2,MAML3,MAX,MAZ,MBD1,MED10,MED13,MED14,MED15,MED17,MED18,MED20,MED23,MED24,MED25,MED26,MED27,MED30,MED31,MED4,MED6,MED7,MED8,MEF2A,MEF2C,MEF2D,MEIS1,MEIS2,MEIS3,MEOX1,MEOX2,MESP1,MESP2,MITF,MIXL1,MLLT1,MLLT3,MNT,MSC,MSGN1,MSX1,MTF1,MYB,MYBL2,MYC,MYCN,MYF6,MYOCD,MYOD1,MYOG,MZF1,NABP1,NANOG,NCBP1,NCBP2,NCOA6,NELFA,NELFCD,NEUROD1,NEUROD6,NEUROG3,NFAT5,NFATC1,NFATC2,NFATC3,NFATC4,NFE2L3,NFIA,NFIB,NFIC,NFIL3,NFIX,NFKB1,NFKB2,NFRKB,NFX1,NFXL1,NFYA,NFYC,NHLH1,NHLH2,NKX2-5,NKX3-2,NKX6-1,NKX6-3,NMI,NOBOX,NOCT,NOTCH1,NOTCH2,NOTCH3,NOTCH4,NPAS4,NR0B1,NR0B2,NR1D1,NR1D2,NR1H2,NR1H3,NR1H4,NR1I2,NR2C1,NR2C2,NR2E3,NR2F6,NR3C1,NR4A1,NR4A2,NR4A3,NR5A2,NRBF2,NRBP1,NRF1,NRL,NUCKS1,ONECUT1,ONECUT3,OTX1,OTX2,OVOL2,PABPN1,PAF1,PAPOLA,PARP1,PATZ1,PAX2,PAX3,PAX5,PAX8,PAX9,PBX1,PBX2,PBX4,PCF11,PCID2,PGR,PHAX,PHOX2B,PHRF1,PIR,PITX1,PITX2,PKNOX1,PLAG1,PLAGL1,PLSCR1,PMF1,POLDIP3,POLR2A,POLR2B,POLR2C,POLR2D,POLR2F,POLR2G,POLR2H,POLR2I,POLR2J,POLR2L,POU1F1,POU2AF1,POU2F1,POU2F2,POU2F3,POU3F2,POU3F4,POU4F1,POU4F3,POU6F2,PPARA,PPARD,PPARG,PPARGC1A,PPM1D,PRDM2,PRDM4,PROP1,PTF1A,PTTG1,RAD21,RARA,RARB,RARG,RAX,RAX2,RBM8A,RBPJ,RBPJL,REL,RELA,REST,RFX5,RFX6,RNGTT,RNMT,RNPS1,RORB,RORC,RPAP1,RPRD1A,RPRD1B,RREB1,RTF1,RUNX1,RUNX2,RXRA,RXRB,RXRG,SALL2,SARNP,SATB2,SCAF1,SCX,SETD2,SETX,SHOX,SIRT1,SIX2,SLBP,SLU7,SMAD2,SMAD4,SNAPC1,SNAPC2,SNAPC3,SNRPD3,SNRPE,SNRPG,SNW1,SOHLH1,SOX1,SOX10,SOX11,SOX12,SOX17,SOX18,SOX2,SOX4,SOX5,SOX9,SP1,SP7,SPI1,SPIB,SPIC,SREBF1,SRF,SRRM1,SRRT,SRSF1,SRSF11,SRSF2,SRSF3,SRSF4,SRSF5,SRSF6,SRSF7,SRSF9,SSBP2,SSBP3,SSRP1,SSU72,STAG1,STAT6,STK16,SUB1,SUPT16H,SUPT3H,SUPT4H1,SUPT5H,SYMPK,TAF1,TAF12,TAF1A,TAF1C,TAF1L,TAF2,TAF4,TAF4B,TAF6,TAF7L,TAF8,TAF9,TAF9B,TARDBP,TBP,TBPL1,TBX19,TBX20,TBX5,TCEA1,TCERG1,TCF15,TCF21,TCF4,TCFL5,TEAD2,TEAD3,TEAD4,TFAM,TFAP2A,TFAP2B,TFAP2C,TFDP2,TFE3,TFEC,TGFB1I1,THOC1,THOC2,THOC3,THOC5,THOC6,THOC7,THRA,THRAP3,THRB,TLX1,TLX2,TOX2,TP53,TP63,TP73,TRIM24,TRIM28,TRIM29,TRIP11,TRIP13,TRPS1,TSC22D1,TTF2,TXK,U2AF1,U2AF1L4,U2AF2,USF1,USF2,VDR,VENTX,VEZF1,WDR33,WDR61,WWP2,WWTR1,XBP1,YAP1,YBX1,YY2,ZBED1,ZBTB1,ZBTB17,ZBTB7B,ZC3H11A,ZC3H8,ZFAT,ZFHX3,ZIC1,ZIC3,ZNF148,ZNF202,ZNF292,ZNF300,ZNF473,ZNF639,ZNF750,ZNF76,ZNF831	TetrapodAncestor	128.612
GO.Biological.Process	GO:0071496	cellular.response.to.external.stimulus	233	4.173662e-133	5.391119e-129	2.313785e-131	1.276228e+0	ABCB4,ADNP,ADORA2B,AES,AGT,AIF1,AIFM1,ALB,AMBRA1,ANKRD1,AOC1,AQP1,AQP2,AQP3,ARHGAP35,ASGR1,ASNS,ATF3,ATF4,ATG14,ATG5,ATP1A1,ATP1A2,ATP2B1,AVPR1A,AXL,BAD,BAK1,BCL10,BCL2,BECN1,BECN2,BGLAP,BHLHA15,BMP6,BMPR2,BNIP3,BRIP1,C12orf66,CADPS2,CARTPT,CASP1,CASP2,CASP5,CASP8,CASR,CBL,CBS,CD40,CDKN1A,CDKN2B,CHEK1,CHMP1A,CLEC16A,COL1A1,CPEB4,CRADD,CYBA,CYP24A1,DAP,DEPDC5,DNAJC15,DNM1L,DSC2,EGFR,EIF2AK2,EIF2AK3,EIF2AK4,ENG,FADD,FADS1,FAS,FBXO22,FGF23,FOS,FOSL1,FOXA2,FOXA3,FOXO1,GABARAPL1,GABARAPL2,GADD45A,GAS2L1,GAS6,GBA,GCN1,GDAP1,GJA1,GLRX2,GLUL,GSDMD,GSTP1,HABP4,HDAC4,HMOX1,HSPA5,HSPA8,IL13,IL15,IL1B,IL6,INHBB,IRF1,ITFG2,ITGA2,JUN,KCNB1,KCNJ2,KCNK4,KIAA1324,KIF26A,KLF10,KPTN,LARS,LCN2,LEP,LRRK2,LTBR,LYN,MAG,MAP1LC3A,MAP1LC3B,MAP1LC3B2,MAP1LC3C,MAP2K4,MAP3K1,MAP3K14,MAP3K2,MAP3K5,MAPK1,MAPK3,MAPK8,MAX,MDM2,MIOS,MMP7,MTMR3,MTOR,MTPN,MYBBP1A,MYOCD,MYOD1,NCOA1,NFKB1,NPRL2,NPRL3,NR1H4,NR4A2,NUAK2,NUDT1,NUDT15,NUPR2,P2RX7,PCK1,PDE2A,PDK2,PENK,PHEX,PICK1,PIEZO1,PIEZO2,PIK3C2B,PIK3C3,PIM1,PMAIP1,PPARG,PPM1D,PPP1R9B,PRKAA1,PRKAA2,PRKD1,PTGER4,PTN,PTPN11,RAC1,RALB,RIPOR1,RNF152,RPTOR,RRAGA,RRAGD,SCX,SESN1,SESN2,SESN3,SFRP1,SFRP2,SH3GLB1,SIPA1,SIRT1,SKP2,SLC1A2,SLC2A1,SLC38A2,SLC39A4,SLC9A1,SOX9,SRD5A1,SREBF1,SREBF2,SRF,STK24,STK26,SZT2,TBL2,TGFB1,TLR3,TLR4,TLR5,TNC,TNFRSF10A,TNFRSF10B,TNFRSF1A,TNFRSF8,TNFSF14,TP53,TXN2,UCN3,UCP2,UPP1,USF1,USF2,VDR,WDR24,WDR59,WNT11,WNT4,WNT9B,WRN,XBP1,ZC3H12A,ZFYVE1	TetrapodAncestor	128.268
GO.Biological.Process	GO:0000122	negative.regulation.of.transcription.from.RNA.polymerase.II.promoter	234	6.986043e-133	9.023872e-129	3.856355e-131	1.135818e+0	ACVR2B,AEBP1,AEBP2,AES,AJUBA,AKIRIN2,ALX1,ANKRD1,ANKRD2,ANKRD33,AR,ARHGAP35,ARID1A,ARID5A,ARID5B,ARX,ASCL1,ASCL2,ATF3,ATF7IP,ATXN1L,AURKB,BACH1,BACH2,BARX2,BATF3,BCL11A,BCL6,BCOR,BEND3,BHLHE40,BHLHE41,BMI1,BMP2,BMP4,BMP6,BRMS1L,BTG2,C1QBP,CALR,CAV1,CBFA2T2,CBX2,CBX4,CBX6,CBX7,CBX8,CC2D1A,CC2D1B,CCND1,CCND3,CCNE1,CD36,CDC73,CDK2,CDK6,CDKN1C,CEBPA,CGGBP1,CHCHD3,CHD8,CIC,CIITA,CITED2,CNBP,CNOT1,CNOT2,COPS2,CRY1,CRY2,CRYM,CTBP1,CTCF,CTNNB1,CUL3,CUX1,CUX2,CXXC5,DAB2IP,DACH1,DACT1,DCAF1,DDX5,DEAF1,DKK1,DLG1,DLL4,DLX4,DMAP1,DMBX1,DMRT1,DNAJA3,DNAJB1,DNAJB5,DNAJC17,DNMT3A,DNMT3B,DR1,DRAP1,DRD3,DUSP22,DUSP26,E2F1,E2F6,E2F7,E2F8,E4F1,EAPP,EDN1,EDNRB,EED,EFNA1,EGR1,EID2,ELK4,EN1,EOMES,EP300,EPC1,EPO,ERF,ESR1,ESR2,ESRRA,ESX1,ETS2,ETV3,ETV3L,ETV6,ETV7,EZH2,EZR,FAM220A,FASLG,FBP1,FERD3L,FEZF1,FGF9,FGFR1,FGFR2,FHL2,FLCN,FOSB,FOXA1,FOXA2,FOXC1,FOXC2,FOXE1,FOXF1,FOXG1,FOXH1,FOXJ1,FOXM1,FOXO1,FOXP2,FOXP3,FOXQ1,FOXS1,FRK,FST,FZD8,GABPA,GATA2,GATA3,GATA6,GCFC2,GLI2,GLI3,GLIS1,GLIS3,GSC,GZF1,H2AFY,H2AFY2,HAMP,HAND1,HBZ,HCFC1,HCFC2,HCLS1,HDAC1,HDAC2,HDAC3,HDAC4,HDAC5,HDAC7,HDAC8,HDAC9,HDGF,HES1,HES2,HES3,HES5,HES6,HES7,HESX1,HEXIM1,HEXIM2,HEY1,HEY2,HEYL,HFE2,HHEX,HIC1,HIF1AN,HINFP,HIPK2,HIST2H3A,HIST2H3C,HIST2H3D,HIVEP1,HMBOX1,HMG20A,HMGA2,HMGB1,HMX1,HNF1B,HNRNPA2B1,HNRNPU,HOMEZ,HSBP1,HSF1,HSF4,ID1,ID3,ID4,IFI27,IFNG,IGBP1,IGF2,IKZF2,INSM1,IRF2,IRF2BPL,IRF3,IRF7,IRF8,ISL1,ISX,JARID2,JAZF1,JUN,JUNB,KANK2,KAT5,KCNIP3,KCTD1,KDM1A,KDM2B,KDM5A,KLF10,KLF11,KLF12,KLF16,KLF17,KLF3,KLF4,KLF5,LEF1,LEFTY1,LEP,LILRB4,LMCD1,LRP8,LRRFIP1,MAD2L2,MAEL,MAF,MAX,MBD2,MBD3,MBD3L1,MCPH1,MDFI,MDM2,MDM4,MECP2,MED25,MEF2A,MEF2C,MEIS2,MEN1,MEPCE,MITF,MLIP,MLX,MLXIPL,MMP12,MNT,MOSPD1,MSC,MSX1,MSX2,MTA2,MTDH,MTF2,MXD1,MXD3,MXD4,MYB,MYC,MYOCD,MYPOP,MYT1L,MZF1,NCK1,NCK2,NCOR2,NEDD4L,NEUROG3,NFATC2,NFATC3,NFATC4,NFE2L3,NFIA,NFIB,NFIC,NFIL3,NFIX,NFKB1,NFKB2,NFX1,NFXL1,NIPBL,NKX2-5,NKX3-2,NKX6-1,NOC2L,NOG,NOP53,NOTCH1,NOTCH3,NPAS1,NR0B1,NR0B2,NR1D1,NR1D2,NR1H2,NR1H3,NR1H4,NR2C1,NR2E3,NR2F6,NR3C1,NR4A2,NR4A3,NRIP1,NSD1,NSD2,NUPR2,OLIG2,OLIG3,ORC2,OSR1,OTUD7B,OVOL1,PAF1,PARP1,PARP15,PARP9,PAWR,PAX4,PAX5,PCBP3,PCGF2,PDE2A,PDGFB,PER1,PER2,PER3,PEX2,PHB,PHF14,PHF6,PIAS1,PIAS4,PKIA,PKIG,PLK1,PLK3,POU1F1,POU4F1,PPARA,PPARD,PPARG,PPP1R13L,PPP1R15A,PRDM1,PRDM13,PRDM16,PRDM5,PRKN,PRMT6,PROP1,PROX1,PRRX1,PSEN1,PSMD10,PTCH1,PTH,PURB,RARA,RARB,RARG,RB1,RBBP7,RBBP8,RBL1,RBPJ,RCOR1,RCOR2,RCOR3,RECQL5,REL,RELA,RELB,RERE,REST,RFX5,RIF1,RIOX2,RIPPLY1,RIPPLY2,RIPPLY3,RITA1,RLIM,RNF168,RNF2,RNF8,RORC,RPL23,RPS14,RPS27A,RREB1,RTF1,RXRA,RYBP,S100A1,SALL2,SAP130,SAP30,SARS,SATB1,SATB2,SCGB1A1,SCRT1,SCRT2,SDR16C5,SEMA4D,SFPQ,SHOX2,SIM2,SIN3B,SIRT1,SIRT2,SIRT7,SKI,SKIL,SLA2,SMAD2,SMAD4,SMAD5,SMAD7,SMARCA2,SMARCA4,SMO,SMURF2,SMYD2,SNAI1,SNAI2,SNAI3,SNCA,SNW1,SORBS3,SOX11,SOX14,SOX15,SOX17,SOX18,SOX2,SOX3,SOX9,SP100,SPEN,SPI1,SPOP,SQSTM1,SREBF1,SREBF2,SRF,STAT1,STAT6,STRAP,SUDS3,SUFU,SUMO1,SUPT4H1,SUPT5H,SUV39H2,T,TAF9B,TAGLN3,TAL1,TBL1X,TBL1XR1,TBX15,TBX18,TBX2,TBX20,TBX22,TBX3,TBX6,TCERG1,TCF21,TCF25,TCF3,TCFL5,TCP10L,TDG,TENM2,TFAP2A,TFAP2B,TFAP2C,TFCP2L1,TGFB1,TGIF1,TGIF2,THAP1,THAP11,THRA,THRB,TIMELESS,TLE1,TLE4,TMBIM6,TMPRSS6,TNF,TP53,TP63,TP73,TPR,TRAF6,TRIB3,TRIM28,TRIM29,TRIM33,TRIM37,TRPS1,TRPV1,TSHZ2,TWIST1,TXN,TXNIP,UBC,UBE2D1,UBE2D3,UBE2I,UHRF1,USP2,USP3,USP9X,UXT,VAX2,VDR,VEGFA,VLDLR,VPS72,WDTC1,WFS1,WNT10B,WWC1,WWC2,WWC3,WWOX,WWP2,WWTR1,YBX1,YBX3,YEATS2,YY1,ZBTB1,ZBTB14,ZBTB16,ZBTB18,ZBTB2,ZBTB20,ZBTB5,ZBTB7A,ZC3H8,ZEB1,ZFHX3,ZFP36,ZFP90,ZFPM1,ZFPM2,ZHX1,ZHX2,ZHX3,ZMYND8,ZNF148,ZNF157,ZNF174,ZNF189,ZNF202,ZNF205,ZNF217,ZNF219,ZNF263,ZNF281,ZNF296,ZNF350,ZNF354A,ZNF354B,ZNF366,ZNF431,ZNF500,ZNF564,ZNF608,ZNF613,ZNF649,ZNF668,ZNF675,ZNF746,ZNF8,ZNF831	TetrapodAncestor	128.045
GO.Biological.Process	GO:0032870	cellular.response.to.hormone.stimulus	235	1.218203e-132	1.573553e-128	6.695969e-131	1.180353e+0	ABCB4,ABCC2,ABHD2,ACACA,ACSL1,ADCY2,ADCY3,ADCY4,ADCY5,ADCY8,ADCYAP1,ADIPOQ,ADIPOR1,ADIPOR2,ADRA2A,AGRP,AGT,AGTR1,AGTR2,AGTRAP,AHCYL1,AIF1,AIFM1,AKAP8,AKT2,ANXA1,AP3S1,APC,APEX1,APOB,APOBEC1,APPL1,AQP1,AR,ARG1,ARID1A,ARID1B,ASIP,ASNS,ATP1A1,ATP1A2,ATP2B1,ATP6AP1,ATP6V0A4,ATP6V0B,ATP6V0C,ATP6V0D1,ATP6V0D2,ATP6V0E1,ATP6V0E2,ATP6V1B1,ATP6V1B2,ATP6V1C1,ATP6V1C2,ATP6V1D,ATP6V1E1,ATP6V1E2,ATP6V1G1,ATP6V1G3,ATP6V1H,AVPR1A,AVPR1B,AVPR2,BAIAP2L2,BBS4,BCAR1,BMP4,BMP7,BRCA1,BRIP1,C2CD5,CA2,CACNA1H,CALCOCO1,CALR,CAMK2A,CAPN10,CARM1,CASP9,CAV1,CAV2,CCKAR,CCL2,CCNA2,CCNE1,CDC5L,CDC6,CDK4,CDK7,CFLAR,CGB1,CGB2,CPEB1,CPEB2,CPS1,CREB1,CRHBP,CRHR1,CRHR2,CRK,CSH1,CSK,CSNK2B,CTNNB1,CTSB,CTSH,CTSL,CYBA,CYFIP1,CYP11B1,CYP11B2,DAXX,DDIT4,DDX17,DDX5,DDX54,DENND4C,DNAJA1,DNMT3B,DUSP1,EDN1,EEF2K,EFNA5,EGFR,EGLN2,EIF4E,EIF4EBP1,ENPP1,ENSG00000278139,EPHA8,EPHX1,ERRFI1,ESR1,ESR2,ESRRA,ESRRB,ESRRG,FBXO32,FER,FGF21,FGF23,FHL2,FKBP4,FOS,FOSB,FOXC2,FOXO1,FOXO4,FSHB,FSHR,GAB1,GAS2L1,GATA6,GCGR,GCK,GCLM,GH1,GH2,GHR,GHRHR,GHSR,GJA1,GLP1R,GLP2R,GNB2,GNG10,GNG11,GNG12,GNG13,GNG2,GNG3,GNG7,GNG8,GNRHR,GOT1,GPER1,GPHB5,GPLD1,GPR22,GRB2,GRIP1,GSK3A,GSTP1,HCRTR1,HCRTR2,HDAC4,HDAC5,HDAC9,HEY1,HMGCS1,HNF4A,HNF4G,HNRNPU,HSF1,IDE,IFNB1,IGF1R,IGF2,IGFBP2,IGFBP7,IL6,INHBA,INHBB,INPP5K,INS,IRS1,IRS2,IRS4,ISL1,JAK2,JAK3,JUN,JUNB,KAT2B,KAT5,KDM3A,KL,KLF9,LATS1,LATS2,LEF1,LEP,LEPR,LHB,LHCGR,LMO2,LPIN1,LYN,MAPK1,MAPK3,MAS1,MAX,MDM2,MED13,MED14,MED17,MED24,MED30,MED4,MEF2C,MEN1,METTL21C,MGARP,MKKS,MSTN,MYOD1,NCOA1,NCOA3,NCOA4,NCOA6,NDEL1,NFKB1,NKX3-1,NKX6-1,NOTCH1,NPAS4,NPC1,NPFFR2,NR0B1,NR0B2,NR1D1,NR1D2,NR1H2,NR1H3,NR1H4,NR1I2,NR2C1,NR2C2,NR2E3,NR2F6,NR3C1,NR4A1,NR4A2,NR4A3,NR5A2,NRIP1,NUP62,OR51E2,OXTR,P2RY4,P2RY6,PADI2,PAK1,PAQR5,PAQR6,PAQR7,PAQR8,PARP1,PAX8,PCK1,PDK2,PDPK1,PGR,PGRMC2,PHB,PHEX,PHIP,PIAS1,PIAS2,PID1,PIK3C2A,PIK3CA,PIK3R1,PIK3R2,PIK3R3,PKLR,PKM,PLA2G1B,PLPP1,PMEPA1,POR,PPARA,PPARD,PPARG,PPARGC1A,PPARGC1B,PRKAA1,PRKAA2,PRKACA,PRKACG,PRKAR1A,PRKAR1B,PRKAR2B,PRKCD,PRKCE,PRKCI,PRKCZ,PRKDC,PRL,PRLR,PTEN,PTGDR,PTGER2,PTGER4,PTGFR,PTH,PTK2,PTPN1,PTPN11,PTPRA,PXN,QRFPR,RAB13,RAB31,RAB8A,RAMP2,RAP1B,RARA,RARB,RARG,RB1,RBFOX2,RBM14,RDX,RELA,REN,REST,RHOQ,RNF14,RNF4,ROBO2,RORB,RORC,RPE65,RWDD1,RXRA,RXRB,RXRG,SAFB,SFRP1,SH2B2,SHC1,SIK1,SIK2,SIRT1,SLC25A33,SLC27A1,SLC2A8,SLC30A10,SLC34A1,SLC5A5,SLC9A1,SLIT2,SLIT3,SMARCC1,SMYD3,SOCS2,SOCS7,SOGA1,SORBS1,SOS1,SOST,SOX10,SP1,SRC,SRD5A1,SREBF1,SRSF5,SST,SSTR1,SSTR2,SSTR3,SSTR4,SSTR5,STAR,STC1,STXBP4,TADA3,TBC1D4,TCIRG1,TGFB1,TGFB1I1,THRA,THRAP3,THRB,TNC,TRIB3,TRIP4,TSHB,TSHR,TUSC5,UBE2L3,UBE3A,UBR5,UCP1,UCP2,UCP3,UGT1A1,UMODL1,USF1,USP8,VAMP2,VDR,WDTC1,WNT1,WNT10B,XBP1,YAP1,YWHAG,YWHAH,ZFP36,ZFP36L1,ZFP36L2,ZNF106	TetrapodAncestor	127.803
GO.Biological.Process	GO:0045787	positive.regulation.of.cell.cycle	236	2.518581e-132	3.253251e-128	1.378496e-130	1.239480e+0	ABL1,AIF1,ANAPC11,ANKRD17,ANXA1,APEX1,APP,ASCL1,ASNS,ATM,AURKA,AURKB,AURKC,BAX,BCL2L11,BECN1,BRCA1,BRD4,BTC,BTG2,C6orf89,CALR,CARM1,CASP2,CCL2,CCNB1,CCND1,CCND2,CCND3,CCNH,CCNK,CCNL1,CCNL2,CCNT2,CD28,CDC25A,CDC25B,CDC25C,CDC42,CDC45,CDC6,CDC73,CDCA5,CDK1,CDK10,CDK2,CDK4,CDK5R1,CDK9,CDKN1A,CDKN1B,CENPJ,CEP120,CHEK1,CHEK2,CIT,CITED2,CKS1B,CKS2,CNOT1,CNOT10,CNOT11,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT8,CRADD,CRLF3,CTGF,CUL3,CUL4A,CXCR5,CYP1A1,DAB2IP,DAZL,DBF4B,DDRGK1,DDX11,DDX3X,DLGAP5,DMRT1,DRD2,DRD3,DUSP3,DYNC1LI1,DYNLT3,E2F1,E2F4,E2F7,E2F8,ECT2,EDN1,EDN3,EGF,EGFR,EIF4E,EIF4EBP1,EP300,EPGN,EREG,ESPL1,FAM58A,FAM83D,FEN1,FGF10,FGFR1,FGFR2,FLT3LG,FNTB,FOSL1,FOXA1,FOXE3,FOXG1,FOXO4,FZD9,GADD45A,GATA6,GDPD5,GEN1,GIPC1,GML,GPER1,GTSE1,H2AFY,HCFC1,HES1,HMGA2,HMGN5,HNRNPU,HSF1,HSP90AB1,HSPA2,ID2,IGF1,IGF2,IL10,IL1A,IL1B,INO80,INS,INSM1,KCNA5,KIF20B,KIF3B,LFNG,LRP5,LRP6,LSM11,MAD2L1,MAP10,MAPRE3,MDM2,MDM4,MECP2,MED25,MEIOC,MEIS2,MEPCE,MIF,MLXIPL,MSX1,MSX2,MTA3,MTBP,MUC1,MYBBP1A,MYOG,NDC80,NEUROG1,NKX3-1,NPM1,NPM2,NR4A3,NSMCE2,NUDT16,NUP62,NUPR2,NUSAP1,OPN1LW,OR1A2,OR2A4,OVOL1,PAF1,PAFAH1B1,PAGR1,PBX1,PCBP4,PCID2,PCNA,PDGFB,PDGFRB,PGGT1B,PHIP,PHOX2B,PIDD1,PIWIL2,PKD1,PKD2,PLAGL1,PLCB1,PLK2,PLK3,PLK4,PML,POC1A,POLDIP2,POU4F1,PPP2R5B,PRDM9,PRKACA,PRKCA,PRKCE,PRMT1,PROX1,PSMD10,PTPN11,RAB11FIP4,RACGAP1,RAD21,RAD23A,RAD51B,RAD51C,RANBP2,RANBP3,RANBP3L,RARA,RB1,RCC2,RDX,RGCC,RGPD4,RHNO1,ROCK2,RPL23,RPS15A,RPS27A,RPTOR,RXFP3,SETMAR,SFN,SFPQ,SH2B1,SHB,SIRT2,SLC6A4,SLF1,SLF2,SMC5,SOX15,SOX4,SPAST,SPDYA,SPHK1,SRC,SRPK2,SSTR5,STXBP4,SVIL,TAL1,TAS1R2,TAS2R13,TBX3,TERT,TFDP2,TGFB1,TGFB2,TGM1,THOC1,THOC5,TMOD3,TNKS1BP1,TOPAZ1,TP53,TP73,TPR,TRIAP1,TRIM21,TRIM32,TTL,TUNAR,UBC,UBE2C,UBE2E2,UHRF2,USP2,USP22,VPS4B,WIZ,WNT10B,WNT4,WNT5A,ZBTB17,ZNF16,ZNF385A	TetrapodAncestor	127.488
GO.Biological.Process	GO:0043087	regulation.of.GTPase.activity	237	2.768626e-132	3.576234e-128	1.508960e-130	1.186854e+0	A2M,ABR,ACAP2,ACAP3,ADAP1,ADAP2,ADCYAP1,ADGRB3,AFDN,AGAP1,AGAP2,AGAP3,AGAP4,AGAP9,AGFG2,AGRN,AJUBA,AKT2,ALDH1A1,ALS2,ALS2CL,AMOT,ANKRD27,APC2,ARAP1,ARAP2,ARAP3,ARFGAP2,ARFGAP3,ARHGAP1,ARHGAP11A,ARHGAP12,ARHGAP15,ARHGAP17,ARHGAP18,ARHGAP19,ARHGAP20,ARHGAP21,ARHGAP22,ARHGAP23,ARHGAP24,ARHGAP25,ARHGAP26,ARHGAP27,ARHGAP28,ARHGAP29,ARHGAP30,ARHGAP31,ARHGAP32,ARHGAP33,ARHGAP35,ARHGAP39,ARHGAP4,ARHGAP42,ARHGAP44,ARHGAP5,ARHGAP6,ARHGAP8,ARHGDIA,ARHGDIB,ARHGEF1,ARHGEF11,ARHGEF12,ARHGEF16,ARHGEF19,ARHGEF37,ARHGEF7,ARL2,ARRB1,ARRB2,ASAP1,ASAP3,AXIN2,BBS4,BCAS3,BCL6,BCR,BVES,C15orf62,CAV2,CCDC125,CCL1,CCL11,CCL13,CCL14,CCL15,CCL15-CCL14,CCL16,CCL17,CCL18,CCL19,CCL2,CCL21,CCL22,CCL23,CCL3,CCL3L3,CCL4,CCL4L2,CCL5,CCL7,CCL8,CCR7,CD40,CDC42EP1,CDC42EP2,CDC42EP3,CDC42EP4,CDC42EP5,CDC42SE1,CDKL5,CHM,CHML,CHN2,CPEB2,CRK,CX3CL1,CXCL13,DAB2IP,DENND1A,DENND1B,DEPDC1,DEPDC1B,DEPDC5,DGKI,DLC1,DNM1L,DNMBP,DOCK10,DOCK11,DOCK2,DOCK4,DOCK8,DOCK9,DVL3,DYNLT1,ECT2,EFNA5,ELMOD1,ELMOD2,EPHA1,EPHA2,EPHA3,EPHA4,EPHA5,EPHB3,ERBB2,ERRFI1,EVI5L,EZH2,F11R,F2R,F2RL1,FAM13A,FAM13B,FGD1,FGD2,FGD3,FGD4,FGD5,FOXJ1,FZD10,GAPVD1,GARNL3,GDI1,GDI2,GNAO1,GNAQ,GNB5,GPR65,GPS1,GRHL3,HACD3,HRAS,HTR2B,INPP5B,IPO5,IQGAP1,IQGAP3,ITGB1,JUN,KALRN,KLRK1,LARS,LLGL2,LRCH1,LRRK2,MET,MKKS,MLST8,MTOR,MTSS1L,MYO9A,MYO9B,NCKAP1L,NDEL1,NET1,NF1,NGEF,NPRL2,NPRL3,NRP1,NTF3,NTRK1,NTRK2,NTRK3,OCRL,OPHN1,PAFAH1B1,PDE6D,PGAM5,PICALM,PIK3R2,PIN1,PIP5K1A,PLCB1,PLEKHG4,PLEKHG6,PLXNB1,PLXNB2,PLXNC1,PLXND1,PREB,PREX1,PRKG1,PROM2,PRR5-ARHGAP8,PTK2,PTK2B,PTPRN2,RAB3GAP1,RAB3GAP2,RABEP1,RABEP2,RABGAP1,RABGAP1L,RACGAP1,RALBP1,RALGAPB,RANBP2,RANBP3,RANBP3L,RAP1A,RAP1GAP,RAP1GAP2,RAP1GDS1,RAPGEF1,RAPGEF2,RAPGEF3,RASA1,RASA2,RASA3,RASA4B,RASAL1,RASAL2,RASAL3,RASGEF1B,RASGRF1,RASGRP1,RASGRP2,RASIP1,RCC2,RDX,RGL3,RGN,RGP1,RGPD4,RGS1,RGS10,RGS13,RGS14,RGS16,RGS17,RGS18,RGS19,RGS2,RGS20,RGS21,RGS3,RGS4,RGS5,RGS6,RGS7,RGS8,RGS9,RGSL1,RHOG,RIC1,RIC8A,RIC8B,RICTOR,RIN2,RIN3,RINL,RIPOR2,RP2,RRP1B,RSU1,RTKN,RTN4R,RUNDC1,S100A10,S1PR1,SBF1,SCRIB,SEMA4D,SFRP1,SGSM1,SGSM2,SGSM3,SH3BP1,SH3BP4,SIPA1,SIPA1L1,SIPA1L2,SIPA1L3,SLIT2,SMAP1,SMAP2,SNX13,SNX18,SNX9,SOD1,SOS1,SPRY1,SPRY2,SRGAP1,SRGAP2,SRGAP2B,SRGAP2C,SRGAP3,STARD13,STARD8,STMN1,STXBP5,STXBP5L,SYDE1,SYDE2,SYNGAP1,TAGAP,TAX1BP3,TBC1D1,TBC1D10A,TBC1D10C,TBC1D14,TBC1D15,TBC1D16,TBC1D17,TBC1D19,TBC1D20,TBC1D21,TBC1D22A,TBC1D22B,TBC1D24,TBC1D26,TBC1D28,TBC1D2B,TBC1D3,TBC1D30,TBC1D3B,TBC1D3F,TBC1D3K,TBC1D4,TBC1D5,TBC1D7,TBC1D8,TBC1D8B,TBC1D9,TBC1D9B,TBCD,TBCK,THY1,TIAM1,TIAM2,TMED2,TNK2,TRIP10,TSC2,USP6NL,VAV1,VAV2,VAV3,VPS9D1,WNT11,WNT4,WNT5A,XCL1,XCL2	TetrapodAncestor	127.447
GO.Biological.Process	GO:0001890	placenta.development	238	2.290799e-131	2.959025e-127	1.243288e-129	1.371948e+0	ABCB4,ADA,ALKBH1,ARID1A,ASCL2,ASH1L,BIRC2,BIRC6,BMP5,BMP7,BMPR2,BSG,CASP8,CCNF,CDKN1B,CDKN1C,CEBPA,CEBPB,CITED1,CTSB,CUL7,CYP27B1,CYR61,DCN,DLX3,DNAJB6,E2F7,E2F8,EGFR,EGLN1,EOMES,EPAS1,EPOR,ETNK2,FBXW8,FGFR2,FOSL1,FZD5,GATA2,GCM2,GGNBP2,GHSR,GJA1,GJB3,GJB5,GRB2,GRHL2,HAND1,HES1,HEY1,HEY2,HIF1A,HS6ST1,HSD17B2,HSF1,HSP90AB1,HTRA1,IGF2,IL10,ITGB8,JUNB,KISS1,KRT19,LDOC1,LEF1,LEP,LHX4,LIF,MAP3K4,MAPK1,MAPK14,MC2R,MDFI,MEN1,NCOA1,NDP,NSDHL,OVOL2,PCDH12,PDGFB,PHLDA2,PKD1,PKD2,PLAC1,PLCD3,PLG,PLK4,PPARD,PPARG,PRDM1,PRDX3,PTGIS,PTK2,RBPJ,RPS6,RSPO3,RXRA,SETD2,SNAI1,SOCS3,SOD1,SPINT1,SPP1,ST14,STC1,STC2,STK4,STOX2,TFEB,TMED2,TRIM28,TTPA,VASH1,VASH2,VDR,WNT7B,ZFAT,ZFP36L1	TetrapodAncestor	126.529
GO.Biological.Process	GO:0000302	response.to.reactive.oxygen.species	239	7.739625e-131	9.997274e-127	4.182960e-129	1.364461e+0	ABL1,ADA,ADAM9,ADPRHL2,AIFM1,AKR1B1,ANKZF1,ANXA1,APEX1,APOA4,APOD,APOE,APTX,AQP1,AREG,ARG1,AXL,BAD,BAK1,BCL2,BECN1,BNIP3,BTK,CAMKK2,CASP3,CAT,CBX8,CCL19,CCNA2,CCR7,CDK1,CDK2,CFLAR,CHUK,COL1A1,CRK,CRYAB,CRYGD,CYP1B1,DNM2,DPEP1,DUSP1,ECT2,EDN1,EEF2,EGFR,EGLN1,ENSG00000256632,ERCC6,ERCC6L2,ETS1,EZH2,FABP1,FANCC,FER,FKBP1B,FOS,FOSL1,FOXO1,FXN,GLRX2,GNAO1,GSTP1,GUCY1B3,HBA1,HBA2,HBB,HDAC2,HMOX1,HNRNPD,HP,HSF1,IL18BP,IL18RAP,IL6,JUN,KCNA5,KCNC2,KDM6B,KLF2,KLF4,KPNA4,LCN2,LDHA,MAP1LC3A,MAP3K5,MAPK1,MAPK3,MAPK8,MAPK9,MB,MDM2,MMP3,MMP9,MPO,MPV17,MYB,NCF1,NET1,NME8,NOS3,NQO1,NR4A3,PARK7,PAX2,PCGF2,PCNA,PDCD10,PDGFD,PDGFRB,PDK2,PKD2,PLEKHA1,PLK3,PPARGC1A,PPARGC1B,PPIF,PPP1R15B,PPP2CB,PPP5C,PRDX1,PRDX2,PRDX3,PRDX5,PRKAA1,PRKCD,PTK2B,PTPRK,PXN,RELA,ROMO1,RPS3,S100A7,SCGB1A1,SETX,SIRT1,SLC8A1,SOD1,SOD2,SOD3,SRC,STAR,STAT6,STK24,STK26,TNFAIP3,TRAF2,TRPA1,TRPC6,TRPM2,TXNIP,TXNRD1,UBE3A,UCP1,UCP2,UCP3,ZNF277,ZNF580	TetrapodAncestor	126
GO.Biological.Process	GO:0050670	regulation.of.lymphocyte.proliferation	240	2.182393e-130	2.818997e-126	1.174582e-128	1.310409e+0	ADA,AGER,AHR,AIF1,ANXA1,ARG1,ARG2,ATAD5,ATM,BCL2,BCL6,BMP4,BST1,BTK,CARD11,CASP3,CCDC88B,CCL19,CCL5,CCR2,CD1D,CD209,CD24,CD274,CD276,CD28,CD300A,CD320,CD38,CD3E,CD40,CD46,CD55,CD59,CD6,CD74,CD80,CD81,CD86,CDKN1A,CEBPB,CHRNB2,CLC,CLCF1,CLEC4G,CLECL1,CORO1A,CTLA4,CTNNB1,DHPS,DLG1,DLG5,DNAJA3,EBI3,EFNB1,EPO,ERBB2,FADD,FGF10,FOXJ1,FOXP3,GAL,GNRH1,GPAM,GPNMB,GPR183,HAVCR2,HES1,HHLA2,HMGB1,IDO1,IFNG,IGF1,IGF2,IGFBP2,IHH,IKZF3,IL10,IL12A,IL12B,IL12RB1,IL13,IL15,IL18,IL1B,IL2,IL20RB,IL21,IL23A,IL23R,IL27,IL4,IL5,IL6,IL6ST,IL7,INPP5D,IRF1,IRS2,ITCH,JAK3,LEP,LGALS3,LGALS9,LILRB2,LRRC32,LST1,LYN,MAD1L1,MEF2C,MIF,MZB1,NCK1,NCK2,NCKAP1L,NDFIP1,NFATC2,PAWR,PDCD1LG2,PDE5A,PELI1,PKN1,PLA2G2D,PLA2G2F,PNP,PRDM1,PRKAR1A,PRKCQ,PTPN22,PYCARD,RAC2,RASAL3,RC3H1,RIPK2,RIPK3,RPS3,SASH3,SCGB1A1,SDC4,SELENOK,SLC39A10,SOS1,SOX11,SPN,SYK,TAC1,TFRC,TGFB1,TGFBR2,TICAM1,TIRAP,TLR4,TLR9,TMEM131L,TMIGD2,TNFRSF13B,TNFRSF13C,TNFRSF14,TNFRSF21,TNFRSF4,TNFSF13B,TNFSF18,TNFSF9,TRAF6,VAV3,VCAM1,VSIG4,VTCN1,WNT3A,XCL1,ZAP70,ZNF335,ZP3,ZP4	TetrapodAncestor	125.55
GO.Biological.Process	GO:0051345	positive.regulation.of.hydrolase.activity	241	5.753966e-130	7.432398e-126	3.083983e-128	1.156282e+0	A2M,ABHD5,ABL2,ABR,ACAP2,ACAP3,ACER2,ADAP1,ADAP2,ADCYAP1,ADCYAP1R1,ADGRB3,ADRA1A,ADRM1,AFDN,AGAP1,AGAP2,AGAP3,AGAP4,AGAP9,AGFG2,AGRN,AGT,AGTR1,AGTR2,AHSA1,AHSA2,AIFM1,AKAP6,AKIRIN2,AKT2,ALDH1A1,ALDOB,ALS2,ALS2CL,ANKRD27,ANTXR1,APAF1,APC2,APOA1,APOA4,APOA5,APOH,APP,ARAP1,ARAP2,ARAP3,ARF4,ARFGAP2,ARFGAP3,ARHGAP1,ARHGAP11A,ARHGAP12,ARHGAP15,ARHGAP17,ARHGAP18,ARHGAP19,ARHGAP20,ARHGAP21,ARHGAP22,ARHGAP23,ARHGAP24,ARHGAP25,ARHGAP26,ARHGAP27,ARHGAP28,ARHGAP29,ARHGAP30,ARHGAP31,ARHGAP32,ARHGAP33,ARHGAP35,ARHGAP39,ARHGAP4,ARHGAP42,ARHGAP44,ARHGAP5,ARHGAP6,ARHGAP8,ARHGDIA,ARHGDIB,ARHGEF1,ARHGEF11,ARHGEF12,ARHGEF16,ARHGEF19,ARHGEF37,ARHGEF7,ARL6IP5,ARRB1,ASAP1,ASAP3,ASPH,ATP1B1,ATP1B2,ATP1B3,AVPR1A,AVPR1B,AXIN2,BAD,BAK1,BAX,BCAP31,BCAS3,BCL10,BCL2L10,BCL2L11,BCL2L13,BCR,BID,BLID,BMP2,C15orf62,C6orf89,CALM1,CALM2,CALM3,CASP1,CASP2,CASP3,CASP8,CASP9,CASR,CAV1,CAV2,CCDC125,CCK,CCL1,CCL11,CCL13,CCL14,CCL15,CCL15-CCL14,CCL16,CCL17,CCL18,CCL19,CCL2,CCL21,CCL22,CCL23,CCL3,CCL3L3,CCL4,CCL4L2,CCL5,CCL7,CCL8,CCR7,CD300A,CD40,CDC42EP1,CDC42EP2,CDC42EP3,CDC42EP4,CDC42EP5,CDKL5,CHM,CHML,CHN2,CHTOP,CIDEB,CLPX,COL4A3,CR1,CRADD,CTGF,CTSH,CX3CL1,CXCL13,CYCS,CYFIP2,CYR61,DAB2IP,DAP,DAPK1,DDRGK1,DDX11,DDX3X,DENND1A,DENND1B,DEPDC1,DEPDC1B,DEPDC5,DHX9,DLC1,DNAJA1,DNAJA2,DNAJB1,DNAJB11,DNAJB6,DNAJC1,DNAJC10,DNAJC2,DNAJC24,DNAJC9,DNAL4,DNM1L,DNM2,DNMBP,DOCK10,DOCK11,DOCK2,DOCK4,DOCK8,DOCK9,DVL3,DYNLL1,DYNLL2,ECT2,EFNA1,EFNA3,EGFR,EGLN3,EIF2AK3,ELMOD1,ELMOD2,EPHA1,EPHA2,EPHA4,ERBB2,ERN1,ERRFI1,ESR1,EVI5L,EZH2,F11R,F2R,F2RL1,F3,FABP1,FADD,FAM13A,FAM13B,FAM162A,FAS,FASLG,FBLN1,FGF10,FGF2,FGFR1,FGFR2,FGFR3,FIS1,FLT1,FN1,FNTA,FOXJ1,FZD10,GABARAPL2,GAPVD1,GARNL3,GDI1,GDI2,GM2A,GNA13,GNA15,GNAO1,GNAQ,GNB5,GPER1,GPIHBP1,GPLD1,GPR55,GPR65,GRAMD4,GRHL3,GSN,HACD3,HIP1,HIP1R,HMGB1,HMGB2,HNRNPU,HPCA,HRAS,HSCB,HSF1,HSP90AB1,HSPA2,HSPA5,HTR2A,HTR2B,HTRA2,IFI27,IFNG,IFT57,INPP5B,IQGAP1,ITGA1,ITGA2,ITGB1,ITK,JAK2,JUN,KALRN,KARS,LARS,LCK,LGALS9,LLGL2,LMF1,LPAR1,LRRK2,LYN,MAGI2,MAP3K5,MAPK14,MAPK3,MAPK8,MAPT,MEF2C,MEFV,MMP14,MSH2,MSH3,MSH6,MTCH1,MTSS1L,MUL1,MYBPC3,MYC,MYL3,MYO9A,MYO9B,NAPA,NCAPH,NCKAP1L,NDEL1,NEK5,NET1,NF1,NGF,NGFR,NKX3-1,NLRC4,NLRP1,NLRP2,NMUR1,NMUR2,NOD1,NPRL2,NPRL3,NR1H2,NR1H3,NRP1,NTF3,NTRK1,NTRK3,OCRL,OPHN1,PARP16,PCNA,PDCD2,PDCD5,PDCD6,PDGFRB,PDPK1,PERP,PFN1,PFN2,PGAM5,PICALM,PIDD1,PIK3R2,PIN1,PINK1,PIP5K1A,PLA2G1B,PLA2G5,PLCB1,PLEK,PLEKHG4,PLEKHG6,PLIN5,PLSCR1,PLXNB1,PMAIP1,PML,PNLIP,POT1,PPARG,PPARGC1B,PPM1F,PPP1R12A,PPP1R15A,PREB,PRELID1,PREX1,PRKCD,PRKCZ,PRKD1,PRKD2,PSME1,PSME2,PSME3,PTAFR,PTH,PTK2B,PTPA,PTPN1,PYCARD,RAB3GAP1,RAB3GAP2,RAB4A,RABEP1,RABEP2,RABGAP1,RABGAP1L,RACGAP1,RALBP1,RALGAPB,RANBP2,RANBP3,RANBP3L,RAP1A,RAP1GAP,RAP1GAP2,RAP1GDS1,RAPGEF1,RAPGEF2,RAPGEF3,RASA1,RASA2,RASA3,RASA4B,RASAL1,RASAL2,RASAL3,RASGEF1B,RASGRF1,RASGRP1,RASGRP2,RASGRP4,RCC2,REST,RGL3,RGN,RGP1,RGPD4,RGS1,RGS10,RGS13,RGS14,RGS16,RGS17,RGS18,RGS19,RGS2,RGS20,RGS21,RGS3,RGS4,RGS5,RGS6,RGS7,RGS8,RGS9,RGSL1,RHOC,RHOG,RIC1,RIC8A,RIC8B,RIN2,RIN3,RINL,RIPK1,RIPK2,RIPK3,ROBO1,RP2,RPS27L,RPS3,RSU1,RTN4R,RUNDC1,RYR2,S100A10,S100A8,S100A9,S1PR1,S1PR4,SCRIB,SELE,SEMA4D,SEMG1,SEMG2,SERPINA6,SERPINB3,SETMAR,SFRP1,SFRP2,SGSM1,SGSM2,SGSM3,SH3BP1,SIPA1,SIPA1L1,SIPA1L2,SIPA1L3,SIRT1,SLC39A10,SMAP1,SMAP2,SNCA,SNX13,SNX18,SNX9,SOS1,SOX7,SRGAP1,SRGAP2,SRGAP2B,SRGAP2C,SRGAP3,SSBP1,ST18,STARD13,STARD8,STXBP5,STXBP5L,SUMO1,SYDE1,SYDE2,SYNGAP1,TAGAP,TAX1BP3,TBC1D1,TBC1D10A,TBC1D10C,TBC1D14,TBC1D15,TBC1D16,TBC1D17,TBC1D19,TBC1D20,TBC1D21,TBC1D22A,TBC1D22B,TBC1D24,TBC1D26,TBC1D28,TBC1D2B,TBC1D3,TBC1D30,TBC1D3B,TBC1D3F,TBC1D3K,TBC1D4,TBC1D5,TBC1D7,TBC1D8,TBC1D8B,TBC1D9,TBC1D9B,TBCD,TBCK,THY1,TIAM1,TIAM2,TNF,TNFRSF10A,TNFRSF10B,TNFSF10,TNFSF15,TNNT2,TOR1AIP1,TOR1AIP2,TRADD,TRAF2,TRIP10,TSC2,TXK,UHRF1,USP6NL,VAPB,VAV1,VAV3,VCP,VEGFA,VPS9D1,VRK3,WDR35,WNT11,WNT3A,WNT4,WNT5A,WRN,XCL1,XCL2,XDH	TetrapodAncestor	125.129
GO.Biological.Process	GO:1900744	regulation.of.p38MAPK.cascade	242	7.079106e-130	9.144081e-126	3.778546e-128	1.613741e+0	AGER,BMP2,CAV3,DAB2IP,DLG1,DUSP10,EZR,GADD45A,GADD45B,GADD45G,GDF6,HAND2,HGF,HSPH1,IL1B,KARS,LEP,MAP3K3,MAP3K4,MAP3K5,NCF1,OPRK1,PER1,PHLPP1,PRMT1,PTPN22,SASH1,ULK4,VEGFA,XDH,ZC3H12A	TetrapodAncestor	125.039
GO.Biological.Process	GO:0030856	regulation.of.epithelial.cell.differentiation	243	9.283485e-130	1.199148e-125	4.934764e-128	1.327374e+0	ACVRL1,ADD1,ADIPOQ,AHI1,AJAP1,ALOX15B,APOLD1,AQP3,ARNTL,ASCL1,ATOH1,ATOH8,BAD,BMP4,BMP6,BTG1,CAV1,CBFB,CCND1,CD109,CD24,CDH5,CDKN1B,CDKN1C,CITED1,CLDN5,CTNNB1,CTSL,CYP27B1,DLL1,ERRFI1,EZH2,FAT4,FOXC1,FOXE3,FOXJ1,FOXN1,GATA3,GDF2,GDF3,GDNF,GRHL2,GSK3A,H2AFY,H2AFY2,HES1,HES5,HEY2,ID1,IFNG,IKBKB,IL13,IL1B,IL20,JAG1,KDF1,KEAP1,KIAA1109,KRT36,KRT84,LHX1,LIF,MAFF,MAFG,MESP1,MSX2,MYCL,MYCN,NCOA3,NKX6-1,NME2,NOTCH1,NOTCH4,NUMB,OSR1,OVOL2,PAX2,PAX8,PRKCH,PRKX,PROC,PROM1,PTCH1,PTCH2,REG3A,REG3G,RFX3,RHEB,ROCK2,RUNX1,S1PR3,SERPINB13,SFN,SFRP4,SMO,SOX9,SRSF6,STAT1,SULT2B1,TBX3,TMEM100,TNF,TNFRSF1A,TP63,VDR,VHLL,WNT10B,WNT9B,WWTR1,XDH,ZEB1,ZFP36,ZFP36L1	TetrapodAncestor	124.921
GO.Biological.Process	GO:1905114	cell.surface.receptor.signaling.pathway.involved.in.cell-cell.signaling	244	3.022361e-129	3.903984e-125	1.599993e-127	1.193403e+0	ADORA1,ADORA2A,AES,AGO1,AGO2,AGO3,AGO4,AMER1,AMER2,AMER3,AMOTL1,AMOTL2,AP2A1,AP2A2,AP2B1,AP2M1,AP2S1,APC,APC2,APCDD1,ARHGEF19,ARL6,ARRB2,AXIN2,BCL7B,BCL9,BCL9L,BMP2,BMP4,BTRC,CALCOCO1,CALM1,CAMK2A,CAV1,CCAR2,CCDC88C,CCND1,CCNE1,CD24,CDC42,CDC73,CDH3,CDK14,CDK5,CELSR1,CELSR2,CHD8,CHRNA10,CHRNA2,CHRNA3,CHRNA5,CHRNA6,CHRNA9,CHRNB2,CHRNB3,CHRNB4,CHRND,CHRNE,CHRNG,CLTC,CPZ,CSNK1A1,CSNK1D,CSNK1E,CSNK1G1,CSNK1G2,CSNK1G3,CSNK2A1,CSNK2A2,CSNK2B,CTNNB1,CTNND1,CTNND2,CUL1,CUL3,CXXC4,DAAM1,DAB2,DACT1,DACT3,DDB1,DDX3X,DGKI,DISC1,DIXDC1,DKK1,DKK2,DKK3,DKK4,DRAXIN,DRD2,DRD4,DVL1,DVL3,EGF,FBXW11,FERMT2,FRAT1,FRAT2,FZD1,FZD10,FZD2,FZD3,FZD4,FZD5,FZD6,FZD7,FZD8,FZD9,GABRB3,GATA3,GLI2,GLRA1,GLRA2,GLRA3,GLRA4,GLRB,GNAO1,GNG2,GPC4,GPC6,GRHL3,GRIA1,GRIA2,GRIA3,GRIA4,GRID1,GRID2,GRIK1,GRIK2,GRIK3,GRIK4,GRIK5,GRIN1,GRIN2A,GRIN2B,GRIN2C,GRIN2D,GRIN3A,GRK5,GRK6,GRM5,GSK3A,HBP1,HHEX,HIC1,HMGXB4,KDM6A,KLF4,KLHL12,KREMEN1,KREMEN2,LEF1,LEO1,LGR4,LGR6,LRP4,LRP5,LRP6,LRRFIP2,LRRK2,MACF1,MAGI2,MAP3K7,MARK1,MARK2,MCC,MECP2,MEF2C,MESD,MOV10,MPP2,MYC,NDP,NFATC1,NKD2,NKX2-5,NLGN3,NLK,NOTUM,NPAS4,NPFF,NPHP3,NR4A2,NXN,OPRM1,OTULIN,P2RX2,P2RX3,P2RX4,P2RX5,P2RX6,P2RX7,PAF1,PARD6A,PDE6A,PDE6B,PFN1,PIAS4,PITX2,PLCB1,PLCB3,PLCG2,PLPP3,PPP1CA,PPP3CA,PPP3CB,PPP3R1,PRICKLE1,PRKAA1,PRKAA2,PROP1,PSEN1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTEN,PTK7,PTPRU,PYGO2,RAB3GAP1,RAB5A,RAC1,RARG,RNF138,RNF146,RNF43,ROR2,RPS27A,RSPO1,RSPO2,RSPO3,RSPO4,RTF1,RYK,RYR2,SCYL2,SENP2,SFRP1,SFRP2,SFRP4,SFRP5,SLC17A7,SLC29A1,SLC9A3R1,SMO,SMURF1,SMURF2,SNAI2,SNCA,SOST,SOSTDC1,SOX17,SOX4,SPIN1,STRN,T,TAX1BP3,TBL1X,TBL1XR1,TCF7L1,TGFB1I1,TIAM1,TLE1,TLE2,TLE3,TLE4,TMEM131L,TMEM64,TNIK,TNKS,TNKS2,TNRC6A,TNRC6B,TNRC6C,TRABD2A,TRABD2B,TRPV1,UBC,VANGL1,VANGL2,VAX2,VPS35,WDR61,WIF1,WISP1,WLS,WNT1,WNT10A,WNT10B,WNT11,WNT16,WNT3,WNT3A,WNT4,WNT5A,WNT6,WNT7A,WNT7B,WNT8A,WNT8B,WNT9A,WNT9B,WWOX,XIAP,ZBED3,ZNRF3	TetrapodAncestor	124.408
GO.Biological.Process	GO:0045604	regulation.of.epidermal.cell.differentiation	245	9.343560e-129	1.206908e-124	4.926154e-127	1.537038e+0	ALOX15B,AQP3,ATOH1,BMP4,CBFB,CD109,CTSL,CYP27B1,DLL1,ERRFI1,EZH2,FOXC1,GDF3,GRHL2,H2AFY,H2AFY2,HES1,HES5,HEY2,IL20,KDF1,KEAP1,KRT36,KRT84,MAFF,MAFG,MSX2,MYCL,MYCN,NCOA3,NME2,NOTCH1,OVOL2,PRKCH,PTCH1,PTCH2,REG3A,REG3G,ROCK2,RUNX1,SERPINB13,SFN,SFRP4,SRSF6,SULT2B1,TP63,VDR,ZFP36,ZFP36L1	TetrapodAncestor	123.918
GO.Biological.Process	GO:0050866	negative.regulation.of.cell.activation	246	3.462725e-128	4.472802e-124	1.818212e-126	1.345510e+0	ABAT,ABR,ADAMTS18,ADGRF5,ADORA2A,ANXA1,APOE,ARG1,ARG2,ATM,AXL,BANK1,BCL6,BCR,BMP4,BPI,BTK,C1QTNF1,CASP3,CCR2,CD274,CD300A,CD300LF,CD74,CD9,CEBPB,CLEC4G,CNR1,CNR2,CTLA4,CYGB,DLG1,DLG5,DTX1,DUSP22,DUSP3,ERBB2,F2,FAM19A3,FAS,FBXO7,FER,FGG,FOXF1,FOXJ1,FOXP3,GAL,GLI3,GNRH1,GPER1,GPNMB,HAVCR2,HLX,HMGB1,HMGB3,HMOX1,IDO1,IFNA2,IFNB1,IFNL1,IHH,IL10,IL13RA2,IL2,IL20RB,IL31RA,IL4,INHA,INHBA,INPP5D,IRF1,ITCH,JAK3,LAX1,LDLR,LGALS3,LGALS9,LILRB2,LOXL3,LRRC32,LST1,LYN,MAD1L1,MERTK,MILR1,NDFIP1,NFKBID,NOS3,NR1H3,PAG1,PAWR,PDCD1LG2,PDE5A,PDGFA,PDGFB,PELI1,PGLYRP1,PGLYRP2,PGLYRP3,PKN1,PLA2G2D,PLA2G2F,PRDM1,PRKAR1A,PRKCD,PRKG1,PTPN22,RC3H1,RHBDD3,RIPOR2,SAMSN1,SCGB1A1,SDC4,SERPINE2,SFRP1,SLA2,SMAD7,SOCS5,SOCS6,SOX11,SPN,TARM1,TBC1D10C,TGFB1,THBD,THOC1,TIGIT,TMEM131L,TNFAIP3,TNFAIP8L2,TNFRSF13B,TNFRSF14,TNFRSF21,TNFSF18,TSPAN32,TYRO3,UBASH3B,VSIG4,VTCN1,XCL1,ZC3H12A,ZC3H8	TetrapodAncestor	123.349
GO.Biological.Process	GO:0043123	positive.regulation.of.I-kappaB.kinase/NF-kappaB.signaling	247	5.975366e-128	7.718380e-124	3.124850e-126	1.365413e+0	ABL1,ADIPOQ,AGER,AJUBA,AKAP13,ANKRD17,APOL3,APP,BCL10,BIRC2,BIRC3,BRD4,BST2,C18orf32,C8orf4,CANT1,CARD11,CARD16,CASP1,CASP10,CASP8,CC2D1A,CCDC22,CCL19,CCL21,CCR7,CD27,CD36,CD40,CD74,CFLAR,CHUK,CLEC6A,CTH,CTNNB1,CXXC5,DDRGK1,ECT2,EDA,EDA2R,EDAR,EEF1D,F2R,F2RL1,FADD,FASLG,FKBP1A,FLNA,GJA1,GOLT1B,GPRC5B,GREM1,HMOX1,HTR2B,IFIT5,IKBKB,IKBKE,IKBKG,IL12B,IL18,IL18R1,IL1B,IL23A,INAVA,IRAK1,IRAK4,IRF3,LGALS1,LGALS9,LITAF,LPAR1,LTBR,LURAP1,MALT1,MAP3K14,MAP3K3,MAP3K7,MIB2,MID2,MIER1,MTDH,MUL1,NDFIP1,NDFIP2,NEK6,NOD1,NUP62,PELI1,PELI2,PIM2,PINK1,PLEKHG5,PLK2,PPP5C,PRKCB,PRKCE,PRKD1,PRKN,RBCK1,REL,RELA,RHOC,RIPK1,RIPK2,RNF31,RPS27A,S100A12,S100A13,S100A4,S100B,SECTM1,SHARPIN,SLC44A2,SPHK1,TAB2,TBK1,TERF2IP,TFG,TGM2,TICAM1,TICAM2,TIRAP,TLR2,TLR3,TLR4,TLR6,TLR9,TMED4,TMEM101,TMEM189-UBE2V1,TNF,TNFRSF10B,TNFRSF19,TNFRSF1A,TNFSF10,TNFSF11,TNFSF14,TNIP2,TRADD,TRAF2,TRAF5,TRAF6,TRIM13,TRIM22,TRIM25,TRIM32,TRIM38,TRIM5,TRIM62,TRIM8,TRIP6,TSPAN6,UBC,UBE2I,UBE2N,UNC5CL,VAPA,WLS,ZDHHC13,ZDHHC17	TetrapodAncestor	123.112
GO.Biological.Process	GO:0045786	negative.regulation.of.cell.cycle	248	6.606095e-128	8.533093e-124	3.440763e-126	1.193044e+0	ABL1,ADCYAP1,ALOX15B,ANGEL2,APAF1,APBB2,APC,ATF5,ATM,ATR,AURKA,AURKAIP1,AURKB,BABAM1,BABAM2,BARD1,BAX,BCL2,BCL2L1,BCL6,BMI1,BMP2,BMP4,BMP7,BRCA1,BRCC3,BRINP1,BRINP2,BRINP3,BRIP1,BRSK1,BTG2,BTG3,BTG4,BUB1,C10orf99,CAB39,CAB39L,CALR,CAMK2N1,CARM1,CASP2,CASP3,CBX3,CCNB1,CCND1,CCNE2,CCNF,CCNG2,CCNK,CDC123,CDC14A,CDC14B,CDC25C,CDC45,CDC5L,CDC6,CDC73,CDK1,CDK2,CDK2AP2,CDK4,CDK5,CDK5RAP1,CDK5RAP2,CDK6,CDK7,CDK9,CDKN1A,CDKN1B,CDKN1C,CDKN2A,CDKN2B,CDKN2C,CDKN2D,CDKN3,CEBPA,CENPF,CENPJ,CEP63,CGREF1,CGRRF1,CHEK1,CHEK2,CHFR,CHMP2A,CHMP4C,CNOT1,CNOT10,CNOT11,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT8,CRADD,CTDSP1,CTDSP2,CTDSPL,CTNNB1,CUL1,CUL2,CUL3,CUL4A,CUL5,CXCL8,DAB2IP,DACT1,DCLRE1B,DCUN1D3,DDIAS,DHCR24,DLG1,DMRT1,DNA2,DONSON,DOT1L,DUSP1,E2F1,E2F4,E2F6,E2F7,E2F8,E4F1,EED,EGFR,EIF2AK4,EIF4G2,EME1,EME2,EP300,EPC1,ERN1,ERN2,ESPL1,EZH2,FANCG,FANCI,FBXL7,FBXO31,FBXO5,FBXO6,FBXO7,FBXW7,FGF10,FOXC1,FOXE3,FOXN3,FOXO4,FZD3,FZD9,FZR1,GADD45A,GADD45GIP1,GAS1,GAS2,GAS2L1,GAS6,GAS7,GATA3,GIGYF2,GJC2,GML,GMNN,GPER1,GPNMB,GPR132,GTSE1,H2AFX,H2AFY,HBP1,HECA,HEPACAM,HEXIM1,HEXIM2,HHEX,HINFP,HMGA2,HMGN5,HPGD,HRAS,HSP90AB1,HTRA2,HUS1,HUS1B,IFNG,IFNW1,IK,IL10,IL12A,IL12B,INCA1,INHA,INHBA,INTS3,IRF1,IRF6,JADE1,JMY,KANK2,KAT2B,KHDRBS1,KIF20B,KIF25,KLHL22,KLLN,KMT2E,L3MBTL2,LAMTOR2,LAMTOR3,LAMTOR4,LATS1,LATS2,LIF,MAD1L1,MAD2L1,MAD2L1BP,MAD2L2,MAGI2,MAP2K6,MAPK14,MAPKAPK2,MAX,MCPH1,MDC1,MDM1,MDM2,MDM4,MEIOC,MEN1,MGA,MIF,MIIP,MLF1,MLST8,MLXIPL,MOS,MRE11,MRNIP,MSH2,MTBP,MTOR,MUC1,MUS81,MYC,MYO16,MYOCD,NAA10,NABP1,NAE1,NANOS2,NBN,NEK11,NKX3-1,NLE1,NOP53,NOTCH1,NOTCH2,NPM1,NPPC,NPR2,NR4A1,NSUN2,NUBP1,NUPR1,NUPR2,ORAOV1,OSM,OVOL1,PCBP4,PCGF2,PCNA,PEA15,PHC1,PHC3,PHOX2B,PIDD1,PINX1,PKD1,PKD2,PLA2G16,PLAGL1,PLK1,PLK2,PLK3,PML,PNPT1,PPM1G,PPP1R13B,PPP1R15A,PPP1R9B,PPP2R3B,PPP2R5B,PRCC,PRKAA1,PRKAA2,PRKAB1,PRKAG2,PRKAG3,PRKAR1A,PRKDC,PRMT1,PRPF19,PRR11,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTEN,PTPN11,PTPN3,PTPRK,PTTG1,PTTG2,RAD1,RAD17,RAD21,RAD51,RAD9A,RB1,RBBP4,RBBP7,RBBP8,RBM14,RFWD3,RGCC,RHEB,RHNO1,RING1,RNF167,RNF2,RPA2,RPA4,RPL23,RPL24,RPRM,RPS27A,RPS27L,RPS6,RPS6KA2,RPTOR,RRAGA,RRAGD,RRM2,RYBP,SART1,SCRIB,SETMAR,SFN,SGSM3,SIPA1,SKIL,SLC38A9,SLC9A3R1,SLFN11,SMARCA4,SMC1A,SOX11,SOX2,SOX4,SPDL1,STAG2,STRADA,STRADB,SUSD2,TAF6,TAOK1,TAOK2,TBRG1,TBRG4,TERF1,TERF2,TEX14,TFDP2,TGFB1,TGFB2,TGFBR1,THAP5,THBS1,TICRR,TIMP2,TIPRL,TMEM67,TNF,TNFAIP3,TNKS,TNKS1BP1,TOM1L1,TOP2A,TOPBP1,TP53,TP53BP2,TP53INP1,TP63,TP73,TPR,TPRA1,TRIAP1,TRIM35,TRIM37,TRIP13,TSC2,TSG101,TTK,UBC,UHMK1,UIMC1,USP28,USP47,UXT,VASH1,VPS4A,WAPL,WEE2,WNT10B,WNT9A,XPC,YAF2,ZBTB17,ZBTB49,ZFP36L1,ZFP36L2,ZFYVE19,ZNF207,ZNF385A,ZNF830,ZW10	TetrapodAncestor	123.069
GO.Biological.Process	GO:0045834	positive.regulation.of.lipid.metabolic.process	249	9.644097e-128	1.245728e-123	5.002924e-126	1.401398e+0	AADAC,ABCD2,ABCG1,ABHD5,ABHD6,ACSL3,ADGRF5,ADIPOQ,ADRB2,AGT,AGTR1,AKT2,AMBRA1,ANXA1,APOA1,APOA2,APOA4,APOA5,APOC1,APOE,ATG14,AVP,AVPR1A,BMP6,C1QTNF2,CCDC3,CCL19,CCL21,CCR7,CD81,CDC42,CNEP1R1,CPT1A,CREB1,CREBL2,CYR61,DGAT2,DISP3,EPHA8,F2,FABP1,FABP3,FGF1,FGF2,FGF21,FGFR3,FGR,FLT1,GHSR,GPLD1,HSD17B13,HTR2A,HTR2B,HTR2C,HTT,IFNG,IL1B,INS,IRS1,IRS2,LDLR,LDLRAP1,LYN,MID1IP1,MLXIPL,MLYCD,MTOR,NR1D1,NR1H2,NR1H3,NR1H4,NR4A3,NSMAF,PDGFB,PDGFRB,PLA2G6,PLIN5,PNPLA2,POR,PPARA,PPARG,PPARGC1A,PRKAA1,PRKCD,PRKCE,PRKD1,PTK2,PTK2B,RGN,SCARB1,SESN2,SIRT4,SLC45A3,SMPD2,SMPD3,SORBS1,SPTLC1,SPTLC2,SRC,SREBF1,STAR,STARD4,TAZ,TEK,TGFB1,TNF,TNFAIP8L3,TNFRSF1A,TWIST1,VAV2,VAV3,WNT4,ZP3	TetrapodAncestor	122.905
GO.Biological.Process	GO:0045930	negative.regulation.of.mitotic.cell.cycle	250	2.020984e-127	2.610505e-123	1.044202e-125	1.282489e+0	ABL1,ANGEL2,APC,ATM,AURKA,AURKAIP1,AURKB,BAX,BCL2,BCL2L1,BCL6,BMP4,BMP7,BRCA1,BRINP1,BRINP2,BRINP3,BTG2,BTG3,BTG4,BUB1,CARM1,CASP2,CCNB1,CCND1,CDC14A,CDC14B,CDC25C,CDC73,CDK1,CDK2,CDK2AP2,CDKN1A,CDKN1B,CDKN2B,CENPF,CENPJ,CHEK1,CHEK2,CHFR,CHMP4C,CNOT1,CNOT10,CNOT11,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT8,CRADD,CTDSP1,CTDSP2,CTDSPL,CTNNB1,CUL1,DACT1,DCUN1D3,DLG1,DONSON,DUSP1,E2F1,E2F4,E2F7,E2F8,E4F1,EGFR,EME1,EME2,EP300,EZH2,FANCI,FBXL7,FBXO31,FBXO7,FOXC1,FOXN3,FOXO4,FZD3,GADD45A,GADD45GIP1,GAS1,GIGYF2,GJC2,GML,GPNMB,GPR132,GTSE1,HECA,HMGA2,HRAS,HUS1,HUS1B,IK,IL10,INTS3,JADE1,KANK2,KIF25,KLHL22,MAD1L1,MAD2L1,MAD2L1BP,MAD2L2,MAGI2,MCPH1,MDC1,MDM2,MDM4,MEIOC,MIIP,MRE11,MRNIP,MSH2,MTBP,MUC1,MUS81,MYO16,NAA10,NABP1,NAE1,NBN,NEK11,NKX3-1,NLE1,NOP53,NPM1,ORAOV1,OVOL1,PCBP4,PCNA,PIDD1,PINX1,PKD2,PLAGL1,PLK1,PLK2,PLK3,PML,PNPT1,PRCC,PRKDC,PRMT1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTEN,PTPN3,PTTG1,PTTG2,RAD17,RAD21,RAD9A,RB1,RFWD3,RGCC,RPA2,RPL24,RPS27A,RPS27L,RPS6,SCRIB,SETMAR,SFN,SLC9A3R1,SLFN11,SMARCA4,SOX4,TEX14,TFDP2,TGFB1,TICRR,TIMP2,TNF,TNKS,TNKS1BP1,TOM1L1,TOP2A,TOPBP1,TP53,TP63,TP73,TPR,TPRA1,TRIAP1,TRIM35,TRIP13,TTK,UBC,USP47,VPS4A,WNT9A,XPC,ZFP36L1,ZFP36L2,ZFYVE19,ZNF207,ZNF385A,ZNF830,ZW10	TetrapodAncestor	122.583
GO.Biological.Process	GO:1902806	regulation.of.cell.cycle.G1/S.phase.transition	251	2.699420e-127	3.486841e-123	1.389180e-125	1.380863e+0	AIF1,ANKRD17,ANXA1,APEX1,ATM,ATP2B4,AURKA,BAX,BCL2,BID,BTG2,C10orf99,C8orf4,CARM1,CASP2,CCL2,CCNB1,CCND1,CCND2,CDC25C,CDC45,CDC6,CDC73,CDK1,CDK10,CDK2,CDK2AP2,CDKN1A,CDKN1B,CDKN2B,CDKN2D,CENPJ,CHEK2,CNOT1,CNOT10,CNOT11,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT8,CRADD,CTDSP1,CTDSP2,CTDSPL,CUL4A,CYP1A1,DACT1,DCUN1D3,DDRGK1,DDX3X,E2F1,E2F4,E2F7,E2F8,ECD,EGFR,EP300,EZH2,FAM83D,FBXO31,FBXO7,FBXW7,FGF10,GADD45A,GIGYF2,GJC2,GML,GPNMB,GTSE1,ID2,INO80,JADE1,KANK2,KCNA5,LSM11,MDM2,MDM4,MEN1,MEPCE,MTBP,MUC1,MYO16,NPM1,PAF1,PAGR1,PCBP4,PCNA,PDPN,PID1,PIDD1,PKD1,PKD2,PLAGL1,PLCB1,PLK2,PLK3,PLK5,PML,PRKDC,PRMT1,PSME1,PSME2,PSME3,PTEN,RB1,RDX,RFWD3,RGCC,RPA2,RPS27A,RPS27L,RPTOR,SFN,SLFN11,SMARCA4,SOX4,STXBP4,SUSD2,TAF1,TERT,TFDP2,TNKS1BP1,TP53,TP63,TP73,TRIAP1,UBC,UBE2E2,ZNF385A	TetrapodAncestor	122.458
GO.Biological.Process	GO:0090092	regulation.of.transmembrane.receptor.protein.serine/threonine.kinase.signaling.pathway	252	3.304142e-127	4.267960e-123	1.693635e-125	1.260998e+0	ABL1,ACVR1B,ACVR2A,ACVR2B,ACVRL1,ADAMTSL2,ASPN,BAMBI,BCL9L,BMP10,BMP15,BMP2,BMP4,BMP5,BMP6,BMP7,BMP8A,BMP8B,BMPER,BMPR1A,BMPR2,CAV1,CAV2,CAV3,CD109,CDKN1C,CDKN2B,CER1,CHRD,CHRDL1,CHST11,CIDEA,CITED1,CITED2,CRB2,CSNK2B,CTDSPL2,CYR61,DAB2,DACT2,DAND5,DKK1,DKK3,DMRT1,DNM2,EID2,ENG,FAM89B,FBN2,FBXL15,FERMT1,FGF10,FGF9,FKBP1A,FLCN,FST,FSTL3,FZD1,GATA4,GATA6,GDF1,GDF10,GDF11,GDF2,GDF3,GDF5,GDF6,GIPC1,GLG1,GPC3,GREM1,GREM2,HES1,HES5,HFE2,HIPK2,HSP90AB1,HSPA5,HTRA1,HTRA3,HTRA4,IL17F,ING2,INHA,INHBA,INHBB,ITGA3,ITGA8,LDLRAD4,LEFTY1,LEFTY2,LEMD2,LEMD3,LRG1,LTBP4,MAGI2,MEN1,MSTN,MSX1,MSX2,MTMR4,MYOCD,NBL1,NEO1,NOG,NOTCH1,NOV,ONECUT1,PARP1,PBLD,PCSK6,PDPK1,PELO,PIN1,PMEPA1,PRDM16,RASL11B,RBPJ,RBPMS,RBPMS2,RPS27A,SDCBP,SFRP1,SFRP2,SFRP4,SFRP5,SIRT1,SKI,SKIL,SKOR2,SMAD2,SMAD4,SMAD7,SMURF1,SMURF2,SNW1,SNX6,SOST,SOSTDC1,SOX11,STRAP,STUB1,TBX20,TFAP2B,TGFB1,TGFB1I1,TGFB2,TGFBR1,TGFBR2,THBS1,TMPRSS6,TRIM33,TTK,UBC,VWC2,VWC2L,WFIKKN1,WNT1,WNT5A,WWTR1,XIAP,ZC3H3,ZEB1,ZNF423,ZNF703	TetrapodAncestor	122.37
GO.Biological.Process	GO:0010634	positive.regulation.of.epithelial.cell.migration	253	6.351207e-127	8.203854e-123	3.242630e-125	1.326724e+0	AAMP,ABL1,ADAM9,ADGRA2,AGT,AMOTL1,ANGPT1,ANGPT4,ANXA3,AQP1,ATOH8,ATP5A1,BCAR1,BCAS3,BMP4,BMPR2,CALR,CAPN7,CCBE1,CCR6,CD40,CIB1,CLASP1,CLASP2,CTSH,DOCK5,EDN1,ENPP2,EPB41L4B,EPB41L5,ETS1,FGF1,FGF10,FGF16,FGF18,FGF2,FGF7,FGFR1,FLT4,FOXC2,GATA3,GLIPR2,GPLD1,HAS2,HBEGF,HDAC7,HDAC9,HIF1A,HSPB1,IFNG,INSL3,ITGA2,ITGA3,JCAD,JUN,MET,MMP9,MTOR,NRP1,NRP2,P2RX4,PDCD6,PDGFB,PFN1,PLCG1,PLPP3,PPM1F,PRKCA,PRKCE,PRKD1,PRKD2,PROX1,PTK2B,RAB25,ROCK2,RREB1,RTN4,SASH1,SCARB1,SEMA5A,SOX9,SRC,SRPX2,TAC1,TDGF1,TEK,TGFB1,TGFB2,TGFBR2,THBS1,VEGFA,VEGFC,VIL1,WNT5A,WNT7A,ZC3H12A,ZNF580	TetrapodAncestor	122.086
GO.Biological.Process	GO:0051147	regulation.of.muscle.cell.differentiation	254	7.972505e-127	1.029808e-122	4.054364e-125	1.301667e+0	ABL1,ADGRB1,AKAP13,AKAP6,ANKRD17,ANKRD2,ARRB2,BCL2,BDNF,BHLHA15,BHLHE41,BMP10,BMP2,BMP4,BOC,BTG1,CAMK1,CAV3,CCL17,CD53,CDC42,CDH2,CDK9,CDON,CFLAR,CMTM5,CTDP1,CTH,CTNNA1,CTNNA2,CTNNB1,CXCL10,CXCL14,CXCL9,CYP26B1,DKK1,DLL1,DMPK,EDN1,EFNB2,EHD1,EHD2,EID2B,ENG,EREG,EZH2,FAM129B,FBXO22,FGFR2,FLOT1,FLOT2,FLT3LG,FOXF1,FOXO4,FRS2,FZD7,G6PD,GDF3,GPER1,GREM1,GSK3A,HAMP,HDAC4,HDAC5,HDAC9,HEY2,HIF1AN,ID3,IGF1,IGF2,IL18,IL4,LMOD3,MAML1,MAMSTR,MAP3K5,MAPK11,MAPK14,MBNL3,MECP2,MED28,MEF2A,MEF2C,MEGF10,MESP1,MMP14,MORF4L2,MSTN,MSX1,MTOR,MYF6,MYLK3,MYOCD,MYOD1,MYOG,NEK5,NFATC2,NKX2-5,NMRK2,NOTCH1,NOV,NRG1,OLFM2,PAK1,PDGFB,PIAS1,PIN1,PLCB1,PPARD,PRICKLE1,PROX1,RANBP3L,RBM24,RBM38,RBM4,RBPJ,RBPMS2,RIPOR2,SCGB3A1,SETD3,SHOX2,SIK1,SIRT1,SMAD4,SMYD1,SOSTDC1,SOX8,SOX9,SPAG9,SRF,TBX1,TBX3,TCF3,TGFB1,THRA,TNF,TNFSF14,TRIM32,TRIM72,TRIP4,WNT3A,XBP1,YBX1,ZEB1,ZFP36L1	TetrapodAncestor	121.987
GO.Biological.Process	GO:0071559	response.to.transforming.growth.factor.beta	255	2.768162e-126	3.575635e-122	1.402210e-124	1.306995e+0	ACVRL1,ADAM9,AMHR2,ANKRD1,APAF1,ARG1,ARRB2,BAMBI,BMPR1A,CAV1,CBL,CCL2,CDH5,CGN,CITED1,CLDN1,CLDN5,CLEC3B,COL1A1,COL1A2,COL3A1,CREB1,CRK,CX3CR1,DUSP15,DUSP22,EDN1,EID2,ENG,EPB41L5,F11R,FERMT2,FGFR2,FKBP1A,FMOD,FNDC4,FNTA,FOS,FOXH1,FSHB,FURIN,FUT8,GCNT2,GDF10,GDF5,HDAC2,HIPK2,HPGD,ID1,ITGB5,JUN,KLF10,LEFTY1,LEFTY2,LTBP4,MAP3K7,MEF2C,MEN1,MSTN,MTMR4,MXRA5,NEDD8,NLK,NOX4,NR3C1,PARD3,PARD6A,PARP1,PDCD5,PDE2A,PDE3A,PDGFB,PDGFD,PENK,PML,PPARGC1A,PRKCZ,PTK2,PTPRK,PXN,RPS27A,SCX,SFRP1,SKI,SKIL,SMAD2,SMAD4,SMAD5,SMAD7,SMURF1,SNRNP70,SOX5,SOX9,SRC,STAR,STK16,TAB1,TGFB1,TGFB2,TGFBR1,TGFBR2,TGFBRAP1,UBC,UBE2M,USP15,USP9X,USP9Y,WNT10A,WNT4,WNT5A,WNT7A,WWOX,XCL1,YES1,ZFHX3,ZFP36L1,ZFP36L2,ZYX	TetrapodAncestor	121.447
GO.Biological.Process	GO:0040013	negative.regulation.of.locomotion	256	6.623384e-126	8.555425e-122	3.341963e-124	1.222710e+0	ABHD2,ABHD6,ABR,ACVRL1,ADA,ADAM15,ADAMTS9,ADARB1,ADGRB1,ADGRG1,ADIPOQ,ADIPOR1,ADORA1,ADORA2A,ADORA3,AGTR2,AIF1,ALOX15B,ANGPT2,ANGPT4,AP1AR,APEX1,APOD,APOE,APOH,ARAP3,ARHGAP4,ARHGDIB,ARID2,ARPIN,ARRDC3,BCL2,BCR,BMP10,BMP5,BMPR1A,BRAF,BST2,C16orf45,C5,C5orf30,CALR,CCDC125,CCL2,CCL21,CCL28,CD300A,CERS2,CHMP3,CHRD,CITED2,CLASP1,CLASP2,COL3A1,CORO1B,CRK,CSNK2B,CTNNA1,CX3CL1,CX3CR1,CXCL13,CYGB,CYP19A1,CYP1B1,DAB2IP,DACH1,DCN,DDT,DLC1,DLG5,DLL4,DPEP1,DPYSL3,DRD2,DUSP10,ENG,EPHA1,EPPIN,EPPIN-WFDC6,ERBB4,EVL,FAM60A,FBLN1,FGF2,FLCN,FRMD5,FUZ,GATA3,GDF2,GHSR,GNRH1,GPR18,GREM1,GSTP1,HDAC5,HMGB1,HMOX1,HRG,IDH2,IFITM1,IGFBP5,IL24,IL33,IL4,KANK1,KLF4,KLRK1,KRIT1,KRT16,LDLRAD4,LRCH1,LRP1,MAGI2,MARVELD3,MCC,MCTP1,MEOX2,MIA3,MID2,MIF,MIIP,MMP28,MMRN2,MYOCD,NAV3,NBL1,NDRG4,NF1,NF2,NISCH,NOG,NOTCH1,NOV,NRG1,NRG3,NRP1,PADI2,PBLD,PDCD10,PFN2,PHLDB2,PIN1,PKP2,PLCB1,PLXNA3,PML,PODN,PPARD,PPARG,PPARGC1A,PTEN,PTGER4,PTN,PTPN23,PTPRG,PTPRJ,PTPRK,PTPRM,PTPRO,PTPRR,PTPRU,RAP2A,RAP2B,RAP2C,RECK,RGCC,RGN,RIPOR2,RNF20,RNF41,ROBO1,ROBO2,RRAS,SCAI,SEMA3A,SEMA5A,SEMA6D,SEMG1,SEMG2,SFRP1,SFRP2,SLC9A3R1,SLIT2,SLURP1,SMAD7,SP100,SPOCK3,SPRED1,SRF,SRGAP1,SRGAP2,SRGAP2B,SRGAP2C,SRGAP3,STAP1,STARD13,STC1,STK24,STK26,STRAP,SYNJ2BP,TACSTD2,TBX5,TGFB1,THBS1,THY1,TIE1,TIMP1,TMEFF2,TMIGD3,TP53INP1,TRIB1,TRIM11,TRIM13,TRIM21,TRIM25,TRIM28,TRIM32,TRIM35,TRIM5,TRIM8,VASH1,VCL,WNT11,WNT3,WNT3A,WNT4,WNT5A,ZMYND8	TetrapodAncestor	121.068
GO.Biological.Process	GO:0061458	reproductive.system.development	257	7.123349e-126	9.201230e-122	3.580245e-124	1.188803e+0	ABCB4,ACVR2A,ADA,ADAM15,ADAMTS1,ADCYAP1,ADGRG1,AFP,AGO4,ALKBH1,ALOX15B,AMH,AMHR2,ANKRD7,ANXA1,AR,ARID1A,ARID4A,ARID5B,ARRB1,ARRB2,ASB1,ASCL2,ASH1L,ASPM,ATM,AXL,BAK1,BASP1,BAX,BCL2,BCL2L1,BCL2L11,BCL2L2,BCL2L2-PABPN1,BIK,BIRC2,BIRC6,BMP15,BMP4,BMP5,BMP6,BMP7,BMPR1B,BMPR2,BRIP1,BSG,CASP2,CASP8,CBL,CCDC182,CCND1,CCNF,CDKN1B,CDKN1C,CEBPA,CEBPB,CHD7,CITED1,COL9A3,CRIP1,CSDE1,CTNNA1,CTNNB1,CTSB,CUL7,CYP19A1,CYP27B1,CYR61,DCANP1,DCN,DHCR24,DLG1,DLX3,DMC1,DMRT1,DMRTA1,DNAJB6,E2F7,E2F8,EGFR,EGLN1,EIF2B4,EIF2B5,EIF2S2,EOMES,EPAS1,EPOR,ERCC1,EREG,ESR1,ETNK2,FANCA,FANCF,FANCG,FBXW8,FEM1B,FGF10,FGF9,FGFR2,FKBP4,FNDC3A,FOSL1,FOXA1,FOXC1,FOXF2,FRS2,FSHB,FSHR,FSTL3,FZD4,FZD5,GATA2,GATA3,GATA4,GATA6,GCM2,GGNBP2,GHSR,GJA1,GJB3,GJB5,GLI2,GLI3,GPR149,GRB2,GRHL2,H3F3A,HAND1,HES1,HEY1,HEY2,HIF1A,HMGB2,HMGCS1,HS6ST1,HSD17B2,HSD17B3,HSD17B4,HSF1,HSP90AB1,HTRA1,ID4,IGF2,IL10,IMMP2L,ING2,INHA,INHBA,INHBB,INSL6,ITGB8,JUNB,KDM5A,KDM5B,KIF18A,KISS1,KITLG,KLHL32,KMT2B,KRT19,LDOC1,LEF1,LEP,LFNG,LGR4,LHB,LHCGR,LHX1,LHX4,LHX8,LIF,LRP6,LRRC6,MAMLD1,MAP3K4,MAPK1,MAPK14,MAS1,MC2R,MDFI,MEA1,MEN1,MERTK,MGST1,MKKS,MMP14,MMP19,MSH2,MSH4,MYOCD,NASP,NCOA1,NCOA4,NDP,NEUROG1,NIPBL,NKX3-1,NOBOX,NOG,NOS3,NOTCH1,NR0B1,NRIP1,NSDHL,NTRK1,NUDT1,NUP107,NUP210L,NUPR1,OSR1,OVOL2,PATZ1,PCDH12,PCYT1B,PDGFB,PDGFRB,PGR,PHLDA2,PITX2,PKD1,PKD2,PLAC1,PLAG1,PLCD3,PLEKHA1,PLEKHA5,PLG,PLK4,PPARD,PPARG,PRDM1,PRDX3,PRDX4,PRKACG,PSAP,PSAPL1,PTCH1,PTEN,PTGIS,PTK2,PTPN11,RAB13,RAD21L1,RARA,RARG,RBP4,RBPJ,RDH10,REC8,REN,RHOBTB3,RNF38,ROBO2,ROR2,RPS6,RSPO3,RXFP2,RXRA,SAFB2,SCX,SERPINA5,SERPINB5,SERPINE2,SETD2,SFRP1,SFRP2,SGPL1,SIRT1,SLIT2,SLIT3,SMAD4,SMARCC1,SNAI1,SOCS3,SOD1,SOHLH1,SOX15,SOX8,SOX9,SPINT1,SPO11,SPP1,SRC,SRD5A1,SRD5A2,ST14,STAR,STC1,STC2,STK4,STOX2,STRA6,SYCP2,TAF4,TBC1D20,TBX3,TCF21,TESC,TEX11,TEX15,TFAP2C,TFEB,TGFB2,TGFBR1,TIFAB,TIPARP,TLR3,TLR5,TMED2,TNC,TNFSF10,TP63,TRIM28,TSPY2,TTPA,TYRO3,UBE2Q1,UBE3A,VASH1,VASH2,VDR,VEGFA,WDR77,WNT4,WNT5A,WNT7A,WNT7B,WNT9B,YBX3,ZFAT,ZFP36L1,ZFP42,ZFPM2,ZNF830	TetrapodAncestor	121.036
GO.Biological.Process	GO:0048589	developmental.growth	258	9.267961e-126	1.197143e-121	4.640087e-124	1.188781e+0	ABL1,ACVR2B,ADAM15,ADARB1,ADD1,ADRA1A,AGT,AGTR2,ALCAM,ALKBH1,ANXA1,APBA1,APBA2,APOA5,APOD,APP,AR,AREG,ARID2,ARID5B,ASPM,ATF5,ATM,AURKA,AUTS2,BCL2,BCL9,BDNF,BIN3,BMP10,BMP4,BMPR1A,BMPR1B,C3orf58,C9orf72,CCL11,CCM2,CCM2L,CCNB1,CDC42,CDK5,CDKN1C,CER1,CFLAR,CHRND,CHST11,COBL,COL27A1,CPQ,CSF1,CTNNB1,CYFIP1,CYFIP2,CYP19A1,DDR1,DDR2,DHCR7,DLL1,DMBX1,DUOX2,DVL1,EFNA5,EIF2AK4,EIF4H,EMX1,EN1,ENSG00000243696,EPB41L5,ERBB4,ERCC1,ERCC2,ERCC6,EREG,ESR1,ETNK2,EVC,EYS,EZH2,FGF1,FGF10,FGF7,FGFR2,FGFR3,FLRT1,FLRT3,FLVCR1,FMN1,FOXC1,FOXC2,FZD7,FZD9,G6PC,GAP43,GAS1,GATA3,GATA4,GIGYF2,GINS1,GINS4,GJE1,GLI2,GLI3,GNAS,GPR149,GRHL2,GSN,H3F3A,HEG1,HHEX,HNF1B,IFRD1,IGF1,IHH,IQGAP1,ITGB1,KDF1,KDM5B,KDM6A,KIF26B,KLF2,LARGE1,LEP,LEPR,LGR6,LHX1,LHX2,LLPH,LRP4,LRP6,MAGI2,MAP1B,MAP2K4,MAPK14,MATN1,MESP1,MEX3C,MMP13,MSTN,MSX2,MTOR,MTPN,MUSTN1,MYF6,MYMK,MYOD1,MYOG,NBN,NCAPG2,NDEL1,NDRG4,NINJ1,NINJ2,NIPBL,NKX2-5,NLGN3,NLGN4X,NOTCH1,NOV,NPPC,NRN1L,NRP1,NRP2,OSTN,PALB2,PAX7,PDE4D,PDGFRB,PDLIM5,PKDCC,PKM,PLAC1,PLAG1,PLEKHA1,PLG,PLXNA1,PLXNA3,PLXNB1,POC1A,POU4F3,PPP1R13L,PPP3CB,PRKAR1A,PRKCZ,PRPF19,PSAP,PSAPL1,PTEN,PTK7,PTPN11,PTPN12,PYGO2,RAPH1,RARA,RARB,RARG,RC3H2,RDH10,RSPO2,RTF1,RXRA,S1PR1,SBDS,SELENOM,SEMA3A,SEMA7A,SFRP1,SFRP2,SH3GL2,SIRT6,SLC12A5,SLC1A2,SLC25A25,SLIT1,SLIT2,SLIT3,SLITRK1,SLITRK6,SMAD2,SMAD4,SMO,SORBS2,SOS1,SOX10,SOX15,SOX2,SOX9,SPG11,SPRY1,SPRY2,SPTBN2,SRF,STC1,STIL,STRA6,TAF8,TAL2,TARBP2,TBL1XR1,TBX2,TEC,TENM4,TGFB1,TGFB2,TGFBR2,THBS3,TIAM1,TM4SF4,TMED2,TMEM108,TMEM110-MUSTN1,TNC,TNKS2,TNS2,TRIM28,TXK,TYMS,UBE3A,UBTFL1,ULK2,USP9X,VANGL2,VCL,WDTC1,WNT10B,WNT11,WNT3A,WNT5A,WNT7A,WNT7B,WWTR1,XPA,XRCC2,ZFP36L1,ZMIZ1,ZNF830,ZPR1	TetrapodAncestor	120.922
GO.Biological.Process	GO:0032940	secretion.by.cell	259	2.887163e-125	3.729348e-121	1.439903e-123	1.151693e+0	A1BG,A2M,ABCA1,ABCA12,ABCA13,ACPP,ACTN1,ACTN4,ACTR10,ACTR2,ACVR2B,ADA2,ADAM8,ADCYAP1,ADGRE3,ADGRE5,ADGRG3,AGA,AGL,AGPAT2,AGT,AGTR2,AHSG,ALAD,ALB,ALDH3B1,ALDOA,ALOX5,ANK1,ANO6,ANPEP,ANXA1,ANXA3,ANXA5,AOC1,AP1M1,AP2A2,APAF1,APBA1,APEH,APLP2,APOA1,APOH,APOOL,APP,AQP1,ARFGAP3,ARFGEF2,ARG1,ARHGAP44,ARL4D,ARL8A,ARPC5,ASAH1,ATAD3B,ATP11A,ATP11B,ATP6AP2,ATP6V0C,ATP6V1D,ATP8A1,ATP8B4,AXL,B4GALT1,BAIAP3,BLOC1S6,BPI,BRPF3,BRSK1,BRSK2,BST1,BST2,BTK,C16orf62,C1QTNF5,C1orf35,C3,C3AR1,C6orf120,CAB39,CADPS,CADPS2,CALM1,CALML5,CAMK2G,CAND1,CANT1,CANX,CAP1,CAPN1,CARD11,CARTPT,CASK,CAT,CBL,CBLN1,CBLN4,CCL19,CCL3,CCL5,CCL8,CCR1,CCR7,CCT2,CCT8,CD109,CD14,CD300A,CD33,CD36,CD44,CD47,CD53,CD55,CD58,CD59,CD63,CD68,CD9,CD93,CDA,CDC37L1,CDK13,CDK16,CDK5,CFP,CFTR,CHAT,CHGA,CHI3L1,CHID1,CHIT1,CHP1,CHRNB4,CKAP4,CKLF,CLEC12A,CLEC3B,CLEC4C,CLEC4D,CLECL1,CLU,CMTM6,COMMD3,COMMD9,CORO1A,COTL1,CPLX1,CPLX2,CPLX3,CPLX4,CPNE3,CPPED1,CR1,CRACR2A,CREB3L1,CREG1,CRHBP,CRHR1,CRISP3,CRISPLD2,CSNK2B,CSTB,CTGF,CTSA,CTSB,CTSC,CTSD,CTSH,CTSW,CTSZ,CXCL1,CXCR1,CXCR2,CYB5R1,CYB5R3,CYB5R4,CYBA,CYBB,CYFIP1,CYSTM1,DBNL,DDOST,DDX3X,DEGS1,DERA,DGAT1,DGKI,DIAPH1,DMTN,DNAJC13,DNASE1L1,DOC2A,DOC2B,DOCK2,DOK3,DPP7,DSC1,DSG1,DSN1,DSP,DVL1,DYNC1H1,DYNC1LI1,DYNLL1,DYNLT1,EDN1,EDN3,EEF1A1,EEF2,EGF,EIF2AK3,ENDOD1,ENG,ENPP4,ENSG00000263620,EPX,EQTN,ERP29,EXOC2,EXOC3,EXOC3L1,EXOC3L2,EXOC4,EXOC5,EXOC6,EXOC6B,EXOC7,EXOC8,F13A1,F2RL1,F5,F8,FABP5,FAF2,FAM129B,FAM3B,FAM3C,FAM49B,FCAR,FCER1G,FCN1,FERMT3,FFAR1,FFAR4,FGF10,FGF7,FGG,FGL2,FGR,FKBP1B,FLG2,FLNA,FN1,FRK,FRMPD3,FTH1,FTL,FUCA1,FUCA2,FURIN,FZD4,GAA,GAL,GAS6,GATA3,GCGR,GDI2,GGH,GHRH,GHRHR,GHSR,GIPC1,GLA,GLB1,GLIPR1,GM2A,GMFG,GNPTAB,GNS,GOLGA7,GOLPH3,GPAM,GPR119,GPR84,GRM2,GRM4,GRN,GSDMD,GSN,GSTP1,GTPBP2,GUSB,GYG1,HABP4,HAP1,HBB,HCK,HEBP2,HGF,HK3,HMGB1,HMOX2,HNF1B,HP,HPSE,HRG,HRH3,HRNR,HSP90AB1,HSPA8,IGF1,IGF2,IGF2R,IL1RAP,IL1RN,IL6,ILDR2,ILF2,IMPDH1,INHBA,IQGAP1,ISLR,IST1,ITGA2B,ITGAM,ITGAV,ITGAX,ITGB2,ITIH3,ITIH4,JAGN1,JUP,KCNAB2,KCNB1,KLRF2,KNG1,KPNB1,KRT1,LAIR1,LAMTOR2,LAMTOR3,LAT,LAT2,LAX1,LCN2,LCP2,LEFTY2,LEP,LGALS3,LGALS3BP,LGI3,LILRB2,LIN7B,LIN7C,LLGL2,LMF1,LRG1,LRMP,LRRC7,LTBP4,LYN,LYZ,M6PR,MAFA,MAGED2,MAN2B1,MANBA,MANF,MAPK1,MAPK14,MC4R,MCEMP1,MCOLN2,MECP2,MERTK,MGAM,MGST1,MIA3,MICAL3,MIF,MILR1,MLEC,MME,MMP25,MMP8,MMP9,MMRN1,MON1A,MOSPD2,MPO,MS4A3,MTTP,MVP,MYO1G,NAAA,NAGPA,NAPRT,NBEAL2,NCKAP1L,NCSTN,NDUFC2,NECAB3,NEUROD1,NF1,NFAM1,NFASC,NFKB1,NHLRC3,NISCH,NIT2,NKD2,NLGN1,NLRC4,NME2,NOS2,NOTCH1,NOX5,NPC2,NPFF,NR1H4,NR4A3,NRAS,NRXN1,NRXN2,NSF,NTRK2,OLFM2,OLFM4,OLR1,ORM1,ORM2,ORMDL3,OSCAR,OSTF1,OTOF,P2RX7,PADI2,PAFAH1B1,PAFAH1B2,PAK1,PARK7,PCDH7,PCLO,PCSK5,PCSK6,PCYOX1L,PDAP1,PDGFA,PDGFB,PDIA4,PDXK,PDZD11,PECAM1,PF4,PFKL,PGAM1,PGLYRP1,PGM2,PGRMC1,PHACTR2,PIGR,PIK3C2A,PIK3CD,PIK3CG,PIP5K1C,PKM,PKP1,PLA2G3,PLAC8,PLAU,PLD1,PLEK,PLEKHO2,PLG,PNP,POU2F2,PPBP,PPFIA1,PPFIA2,PPFIA3,PPFIA4,PPIE,PPP3CB,PPY,PRCP,PRDX4,PREB,PRG2,PRG3,PRKCD,PROS1,PRSS12,PRSS2,PRSS3,PSAP,PSEN1,PSMA2,PSMB1,PSMB7,PSMC2,PSMC3,PSMD1,PSMD11,PSMD13,PSMD2,PSMD3,PSMD7,PTAFR,PTGES2,PTPRB,PTPRJ,PTPRN2,PTX3,PYCARD,PYGB,QPCT,QSOX1,RAB11B,RAB11FIP1,RAB11FIP2,RAB11FIP5,RAB14,RAB15,RAB18,RAB1A,RAB24,RAB26,RAB27A,RAB27B,RAB31,RAB37,RAB3D,RAB44,RAB4B,RAB5B,RAB6A,RAB7A,RAB8A,RAB8B,RAB9B,RABEPK,RAC1,RAF1,RALA,RAP1A,RAP1B,RAP2B,RAP2C,RARRES2,RASGRP1,RBPJ,RETN,RHOG,RIMS1,RIMS3,RIMS4,RNASET2,RPH3A,RPH3AL,RSG1,S100A11,S100A12,S100A13,S100A7,S100A8,S100A9,S100P,SCAMP5,SCCPDH,SCFD1,SCFD2,SCG2,SCG3,SCIN,SCRIB,SCRN1,SDCBP,SDF4,SEL1L,SELENOM,SELENOP,SELENOT,SELL,SELP,SEPT5,SERPINA1,SERPINA3,SERPINA4,SERPINB1,SERPINB10,SERPINB12,SERPINB3,SERPINB6,SERPINE2,SERPING1,SIGLEC9,SIRPA,SIRPB1,SLC11A1,SLC15A4,SLC17A7,SLC18A3,SLC1A1,SLC1A2,SLC1A3,SLC1A5,SLC1A6,SLC1A7,SLC22A2,SLC27A2,SLC2A3,SLC30A8,SLC38A2,SLC44A2,SLC5A7,SLC6A9,SLCO4C1,SLPI,SMAD2,SMPD3,SNAP23,SNAP25,SNAP29,SNAPIN,SNCG,SNPH,SNX19,SOD1,SPP2,SRCIN1,SRP14,STBD1,STEAP2,STEAP3,STK11IP,STOM,STX11,STX19,STX1A,STX1B,STX3,STX4,STXBP1,STXBP2,STXBP5,STXBP5L,SURF4,SVIP,SYCN,SYK,SYN1,SYN3,SYNGR1,SYNGR2,SYNGR3,SYNJ1,SYT1,SYT10,SYT11,SYT13,SYT15,SYT17,SYT2,SYT4,SYT5,SYT6,SYT7,SYT8,SYT9,SYTL1,SYTL2,SYTL3,SYTL4,SYTL5,TAGLN2,TARM1,TBC1D10C,TBX3,TCIRG1,TCN1,TEX264,TF,TGFB1,TGFB2,THBS1,TICAM2,TIMP1,TIMP2,TIMP3,TLN1,TLR2,TLR4,TLR6,TMBIM1,TMC6,TMED10,TMEM167A,TMEM167B,TMEM173,TMEM63A,TMEM79,TMX3,TNFAIP6,TNFRSF1B,TNFSF13B,TOLLIP,TOM1,TRAPPC1,TREM1,TRIM72,TRIM9,TRPM2,TRPV1,TSG101,TSPOAP1,TTN,TTR,TUBB,TUBB4B,TVP23A,TVP23B,TVP23C,TXLNA,TXNDC5,TYRO3,UBE2Q1,UBR4,UNC13A,UNC13B,UNC13C,USE1,VAMP1,VAMP2,VAMP3,VAMP5,VAMP8,VAPA,VAT1,VCL,VCP,VEGFA,VEGFB,VEGFC,VEGFD,VIP,VMP1,VNN1,VPS11,VPS18,VPS33B,VPS41,VPS45,VTCN1,VTI1B,VWF,WDR1,WLS,WNT7A,XRCC5,XRCC6,YKT6,YPEL5,ZP4	TetrapodAncestor	120.428
GO.Biological.Process	GO:2001235	positive.regulation.of.apoptotic.signaling.pathway	260	4.601392e-125	5.943618e-121	2.286007e-123	1.378149e+0	ADORA2A,AGT,AGTR2,APAF1,ATF3,ATPIF1,BAD,BAK1,BAX,BCAP31,BCL10,BCL2,BCL2L1,BCL2L11,BCLAF1,BID,BIK,BMPR1B,BNIP3,CASP2,CASP8,CAV1,CIDEB,CRADD,CTNNA1,CTSC,CTSH,DAB2IP,DAPK3,DEDD2,DFNA5,DNM1L,DYNLL1,DYNLL2,E2F1,FADD,FAF1,FAM162A,FAS,FASLG,FBXO18,FBXW7,FIS1,G0S2,GPER1,GSK3A,GSN,HIP1R,HRK,HTRA2,IFNB1,IL19,IL20RA,INCA1,INHBA,INHBB,ITM2C,JAK2,LCK,LGALS9,LTBR,MAPK8,MAPK9,MFF,MLLT11,MMP9,MSX1,NCK1,NCK2,NF1,NFATC4,NKX3-1,NMT1,OSM,PAK2,PARK7,PDCD5,PDIA3,PEA15,PIAS4,PIDD1,PINK1,PLA2G6,PLEKHF1,PMAIP1,PML,PPIF,PPP1R13B,PPP2R1B,PPP3CC,PPP3R1,PRKCD,PRKRA,PTEN,PYCARD,RAD9A,RBCK1,RET,RIPK1,RIPK3,RPL11,RPS3,RPS7,S100A8,S100A9,SEPT4,SERINC3,SFN,SFPQ,SFRP1,SIAH1,SIRT1,SKIL,SLC9A3R1,SOD1,SPOP,SRPX,ST18,STK4,TFDP2,TGFBR1,THBS1,TIMP3,TNFRSF10A,TNFRSF10B,TNFRSF12A,TNFSF10,TNFSF12,TP53,TP53BP2,TP53INP1,TP63,TP73,TPD52L1,TRADD,TRAF2,TRAF7,TRIM39,WDR35,WWOX,YWHAB,YWHAE,YWHAG,YWHAH,YWHAZ,ZNF205,ZSWIM2	TetrapodAncestor	120.226
GO.Biological.Process	GO:0002763	positive.regulation.of.myeloid.leukocyte.differentiation	261	2.714144e-124	3.505860e-120	1.343241e-122	1.573357e+0	ACIN1,ATP6AP1,CA2,CASP8,CCR1,CD101,CD74,CREB1,CSF1,FADD,FOS,GNAS,GPR68,HAX1,HCLS1,IFNG,IL12B,IL17A,IL20,IL23A,IL23R,IL34,IL5,JUN,KITLG,KLF10,LEF1,LIF,OCSTAMP,PF4,POU4F1,PPARGC1B,PRKCA,RB1,RIPK1,ROR2,RUNX1,SLC9B2,TESC,TMEM64,TNF,TNFSF11,TRAF6,TRIB1,ZFP36L1	TetrapodAncestor	119.455
GO.Biological.Process	GO:0007173	epidermal.growth.factor.receptor.signaling.pathway	262	3.304303e-124	4.268168e-120	1.629072e-122	1.541145e+0	ABL1,AREG,BCAR1,BTC,CBL,CBLB,CSK,DGKD,EFEMP1,EGF,EGFR,EPS15,EPS8,EREG,FAM83B,FES,GAB1,GAREM1,GRB2,GRB7,HBEGF,HRAS,IQGAP1,KIF16B,KRAS,NCK2,NRAS,PAG1,PDPK1,PIGR,PIK3C2A,PIK3CA,PIK3R1,PLCE1,PLCG1,PTK2,PTK2B,PTPN11,PXN,RASSF2,REPS2,RPS6KA5,SHC1,SHC3,SLC30A10,SOCS5,SOS1,SOX9,SRC,STYK1,TGFB1,VIL1	TetrapodAncestor	119.37
GO.Biological.Process	GO:0040007	growth	263	1.692053e-123	2.185625e-119	8.310361e-122	1.178041e+0	ABL1,ACVR2B,ADAM15,ADARB1,ADD1,ADRA1A,AGT,AGTR2,ALCAM,ALKBH1,AMH,ANXA1,APBA1,APBA2,APOA5,APOD,APP,AR,AREG,ARID2,ARID5B,ASPM,ATAD3A,ATF5,ATM,AURKA,AUTS2,BCL2,BCL2L1,BCL9,BDNF,BIN3,BMP10,BMP4,BMPR1A,BMPR1B,C3orf58,C9orf72,CCL11,CCM2,CCM2L,CCNB1,CDC42,CDK5,CDKN1C,CER1,CFLAR,CHRND,CHST11,CNTF,COBL,COL27A1,CPQ,CSF1,CTNNB1,CYFIP1,CYFIP2,CYP19A1,DDR1,DDR2,DDX5,DGKD,DHCR7,DLL1,DMBX1,DUOX2,DVL1,EFNA5,EIF2AK4,EIF4H,EMP1,EMP3,EMX1,EN1,ENSG00000243696,EPB41L5,ERBB4,ERCC1,ERCC2,ERCC6,EREG,ESR1,ETNK2,EVC,EYS,EZH2,FGF1,FGF10,FGF7,FGFR2,FGFR3,FLRT1,FLRT3,FLVCR1,FMN1,FOXC1,FOXC2,FOXP2,FSHR,FZD7,FZD9,G6PC,GAP43,GAS1,GATA3,GATA4,GIGYF2,GINS1,GINS4,GJE1,GLI2,GLI3,GNAS,GPR149,GRHL2,GSN,H3F3A,HEG1,HHEX,HNF1B,HSPG2,IFRD1,IGF1,IHH,IL7R,IQGAP1,ITGAV,ITGB1,KDF1,KDM5B,KDM6A,KIF26B,KLF2,LARGE1,LEFTY1,LEFTY2,LEP,LEPR,LGR6,LHCGR,LHX1,LHX2,LLPH,LRP4,LRP6,MAGI2,MAP1B,MAP2K4,MAPK14,MATN1,MESP1,MEX3C,MMP13,MSTN,MSX2,MTOR,MTPN,MUSTN1,MYF6,MYMK,MYOD1,MYOG,NBN,NCAPG2,NDEL1,NDNF,NDRG4,NINJ1,NINJ2,NIPBL,NKX2-5,NLGN3,NLGN4X,NOP58,NOTCH1,NOV,NPM1,NPPC,NRN1L,NRP1,NRP2,NUBP1,NUPR1,OPA3,OSTN,PAK4,PAK5,PALB2,PAX7,PDE4D,PDGFRB,PDLIM5,PGLYRP1,PGLYRP2,PGLYRP3,PKDCC,PKM,PLAC1,PLAG1,PLEKHA1,PLG,PLXNA1,PLXNA3,PLXNB1,POC1A,POU4F3,PPP1R13L,PPP3CB,PRKAR1A,PRKCZ,PRMT6,PRPF19,PSAP,PSAPL1,PTEN,PTK7,PTPN11,PTPN12,PYGO2,RAPH1,RARA,RARB,RARG,RC3H2,RDH10,RFTN1,RSPO2,RTF1,RXRA,S1PR1,SAFB,SBDS,SEC61A1,SELENOM,SELENOP,SEMA3A,SEMA7A,SFRP1,SFRP2,SH3GL2,SIRT6,SLC12A5,SLC1A2,SLC25A25,SLC3A2,SLIT1,SLIT2,SLIT3,SLITRK1,SLITRK6,SMAD2,SMAD4,SMO,SOCS5,SORBS2,SOS1,SOX10,SOX15,SOX2,SOX9,SPG11,SPRY1,SPRY2,SPTBN2,SRC,SRF,ST6GAL2,STC1,STIL,STRA6,TAF8,TAL2,TARBP2,TBL1XR1,TBX2,TEC,TENM4,TGFB1,TGFB2,TGFBR2,THBS3,TIAM1,TM4SF4,TMED2,TMEM108,TMEM110-MUSTN1,TNC,TNKS2,TNN,TNS2,TRIM28,TXK,TYMS,UBE3A,UBTFL1,ULK2,USP9X,VANGL2,VCL,VEGFA,VPS54,WDTC1,WNT10B,WNT11,WNT3A,WNT5A,WNT7A,WNT7B,WWTR1,XPA,XRCC2,ZFP36L1,ZMIZ1,ZNF830,ZPR1	TetrapodAncestor	118.66
GO.Biological.Process	GO:0061138	morphogenesis.of.a.branching.epithelium	264	4.094355e-123	5.288678e-119	2.003287e-121	1.262140e+0	ADAMTS16,AR,AREG,B4GALT1,BCL2,BMP2,BMP4,BMP7,BTRC,CASR,CCL11,CELSR1,CITED1,CSF1,CTNNB1,CTSH,CTSZ,DCHS1,DDR1,DLG1,DLG5,DLL4,EDN1,EGF,ENG,EPHA2,ESR1,ESRP2,EYA1,FAT4,FEM1B,FGF1,FGF10,FGF2,FGF7,FGFR1,FGFR2,FOXA1,FOXC2,FOXF1,FRS2,FZD5,GBX2,GDF2,GDNF,GLI2,GLI3,GNA13,GPC3,GRB2,GREM1,GRHL2,GZF1,HHEX,HNF1B,IHH,IL10,IL6,KDM5B,KRAS,LAMA5,LEF1,LHX1,LRP5,MET,MKS1,MMP14,MSX2,MYC,MYCN,NFATC4,NKX3-1,NOG,NOTCH1,NOTCH4,NRP1,PAK1,PAX2,PAX8,PBX1,PGR,PITX2,PKD1,PKD2,PLXNA1,PLXND1,PML,PROX1,PTCH1,RASIP1,RDH10,RSPO2,RSPO3,SEMA3A,SEMA3C,SEMA3E,SFRP1,SFRP2,SLIT2,SMAD4,SOCS3,SOX10,SOX8,SOX9,SPINT1,SPRY1,SPRY2,SRC,SRF,ST14,STK4,TBX20,TBX3,TCF21,TGFB1,TGFBR2,TGM2,TIMELESS,TNC,TP63,VANGL2,VDR,VEGFA,WNT1,WNT4,WNT5A,WNT6,WNT9B	TetrapodAncestor	118.277
GO.Biological.Process	GO:1902807	negative.regulation.of.cell.cycle.G1/S.phase.transition	265	4.159442e-123	5.372751e-119	2.027453e-121	1.508303e+0	ATM,AURKA,BAX,BCL2,BTG2,C10orf99,CARM1,CASP2,CCNB1,CCND1,CDC25C,CDC73,CDK1,CDK2,CDK2AP2,CDKN1A,CDKN1B,CDKN2B,CDKN2D,CENPJ,CHEK2,CNOT1,CNOT10,CNOT11,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT8,CRADD,CTDSP1,CTDSP2,CTDSPL,DACT1,DCUN1D3,E2F1,E2F4,E2F7,E2F8,EP300,EZH2,FBXO31,FBXO7,GADD45A,GIGYF2,GJC2,GML,GPNMB,GTSE1,JADE1,KANK2,MDM2,MDM4,MEN1,MUC1,MYO16,NPM1,PCBP4,PCNA,PIDD1,PKD2,PLAGL1,PLK2,PLK3,PML,PRKDC,PRMT1,PTEN,RB1,RFWD3,RGCC,RPA2,RPS27A,RPS27L,SFN,SLFN11,SMARCA4,SOX4,SUSD2,TFDP2,TNKS1BP1,TP53,TP63,TP73,TRIAP1,UBC,ZNF385A	TetrapodAncestor	118.27
GO.Biological.Process	GO:0090257	regulation.of.muscle.system.process	266	6.269361e-123	8.098134e-119	3.044411e-121	1.258929e+0	ABAT,ABCC8,ACE2,ADA,ADORA1,ADORA2B,ADRA1A,ADRA1B,ADRA1D,ADRA2A,ADRA2B,ADRA2C,ADRB2,AGT,AIF1,AKAP13,AKAP6,ANK2,ANXA6,ARHGAP42,ATP1A1,ATP1A2,ATP1B1,ATP2A1,ATP2B4,BMP10,CACNA1C,CALCRL,CALM1,CALM2,CALM3,CAMK2B,CAMK2D,CAMK2G,CASQ1,CASQ2,CAV1,CAV3,CDK9,CHGA,CHRM1,CHRM2,CHRM3,CHRNA3,CHRNB4,CNN1,CTDP1,CTGF,CTNNA3,CTTN,DAPK3,DCANP1,DLG1,DMD,DMPK,DOCK4,DOCK5,DSC2,DSG2,DSP,EDN1,EDN2,EHD3,ENSG00000240045,ERRFI1,F2R,FBXO32,FGF13,FKBP1B,FLNA,FOXO1,G6PD,GATA4,GHSR,GLRX3,GPER1,GRK2,GSK3A,GSTM2,GTF2I,GTF2IRD1,GUCY1A3,HAMP,HAND2,HCN4,HDAC4,HRC,HSPB6,IGF1,IGFBP5,IL6ST,ITGA2,JARID2,JUP,KCNA1,KCNB2,KCNE3,KCNJ2,KCNQ1,KLF4,LMCD1,LMNA,MEF2A,MLIP,MSTN,MTMR4,MTOR,MTPN,MYBPC3,MYBPH,MYH7,MYL3,MYL5,MYL9,MYLK2,MYOCD,MYOG,NEUROG1,NKX2-5,NMUR2,NOL3,NOS1,NOS1AP,NOS3,NPY2R,NR4A3,OXT,OXTR,P2RX4,PAK1,PARP1,PDE4B,PDE4D,PDE5A,PDE9A,PIK3CG,PIN1,PKP2,PLCE1,PLN,PPARGC1A,PPP1R12B,PPP3CA,PRKACA,PRKCA,PRKG1,PROK2,PTAFR,RGS2,RNF207,RYR2,SCN5A,SLC8A1,SLC8A3,SLC9A1,SLN,SMAD4,SMAD7,SOD1,SPHK1,SPX,SRF,SRI,SSTR2,STC1,SUMO1,TACR3,TBXA2R,TIFAB,TNNC1,TNNC2,TNNI2,TNNI3,TNNI3K,TNNT1,TNNT2,TNNT3,TRIM63,TRPC3,TRPM4,TWF1,UCN,UTRN,ZC3H12A	TetrapodAncestor	118.092
GO.Biological.Process	GO:0002764	immune.response-regulating.signaling.pathway	267	9.131890e-123	1.179566e-118	4.417851e-121	1.229155e+0	ABI1,ABL1,ACTR2,ACTR3,APOB,ARPC1A,ARPC1B,ARPC2,ARPC4,ARPC5,BAG6,BAX,BCAR1,BCL10,BCL2,BIRC2,BIRC3,BLK,BRAF,BTK,BTRC,C3AR1,CALM1,CARD11,CASP8,CD14,CD180,CD19,CD209,CD24,CD247,CD28,CD300LF,CD36,CD38,CD3D,CD3E,CD3G,CD40,CD79B,CD86,CDC42,CHUK,CLEC12B,CLEC4A,CLEC4C,CLEC4D,CLEC4E,CLEC6A,CLEC7A,CNPY3,COLEC12,CR1,CR2,CRK,CSK,CTLA4,CTSB,CTSH,CTSL,CUL1,CYFIP1,CYFIP2,DDX58,DENND1B,DMBT1,ELMO1,ELMO2,ENSG00000173366,EP300,FADD,FBXW11,FCER1G,FCGRT,FCN1,FER,FFAR2,FGG,FGR,FOS,FOXP3,FYB1,FYB2,GAB2,GATA3,GPLD1,GPR32,GPR33,GRAP2,GRB2,HAVCR2,HCK,HMGB1,HRAS,HSP90AB1,HSP90B1,ICAM2,IFNG,IGLL1,IGLL5,IKBKB,IKBKE,IKBKG,IL20RB,INAVA,INPP5D,IRAK1,IRAK3,IRAK4,IRF3,IRF7,IRGM,ITCH,ITGAM,ITGB2,ITK,JUN,KLHL6,KLRK1,KRAS,LAT,LAT2,LAX1,LBP,LCK,LCP2,LGMN,LILRA4,LILRB2,LIMK1,LRRC70,LY96,LYN,MALT1,MAP2K4,MAP2K6,MAP2K7,MAP3K1,MAP3K7,MAPK1,MAPK10,MAPK3,MAPK8,MAPK9,MAPKAPK2,MAPKAPK3,MARCO,MEF2C,MS4A2,MUC1,MUC12,MUC13,MUC15,MUC20,MUC3A,MUC4,MUC5AC,MUC5B,MUC6,MUCL1,MYO10,MYO1C,MYO1G,NCK1,NCKAP1,NCKAP1L,NCR3,NFAM1,NFATC1,NFATC2,NFATC3,NFKB1,NOD1,NR1H4,NR4A3,NRAS,OTULIN,PAG1,PAK1,PAK2,PAK3,PDE4B,PDE4D,PDPK1,PGLYRP1,PGLYRP2,PGLYRP3,PGLYRP4,PIGR,PIK3AP1,PIK3C3,PIK3CA,PIK3CD,PIK3R1,PIK3R2,PLA2G6,PLCG1,PLCG2,PLD2,PLEKHA1,PLPP4,PPP3CA,PPP3CB,PPP3R1,PRKACA,PRKACG,PRKCB,PRKCD,PRKCE,PRKCQ,PRKD2,PSEN1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTK2,PTPN22,PTPRJ,RAC1,RAF1,RBCK1,REG3G,RELA,RELB,RFTN1,RFTN2,RIPK1,RIPK2,RNF31,RPS27A,RPS6KA3,RPS6KA5,S100A1,S100A14,S100A8,S100A9,SHB,SHC1,SKAP2,SLA2,SNAI3,SOS1,SPG21,SPPL3,SRC,SYK,TAB1,TAB2,TAB3,TBK1,TEC,THEMIS,THEMIS2,THY1,TICAM1,TICAM2,TIRAP,TLR1,TLR10,TLR2,TLR3,TLR4,TLR5,TLR6,TLR9,TMEM189-UBE2V1,TNFAIP3,TNFRSF21,TNIP1,TNIP2,TNIP3,TRAF3,TRAF6,TRAT1,TRIL,TRIM5,TXK,UBC,UBE2D1,UBE2D2,UBE2D3,UBE2N,UNC93B1,VAV1,VAV2,VAV3,WASF2,WIPF2,WIPF3,YES1,ZAP70	TetrapodAncestor	117.928
GO.Biological.Process	GO:0050764	regulation.of.phagocytosis	268	1.575710e-122	2.035345e-118	7.594569e-121	1.641376e+0	ABR,ADIPOQ,AHSG,ALOX15,ANO6,ATG3,ATG5,BCR,C3,C4A,C4B,C4BPA,C4BPB,CALR,CAMK1D,CCL2,CD300A,CD300LF,CD36,CD47,CSK,CYBA,DNM2,DOCK2,F2RL1,FCER1G,FGR,GAS6,GATA2,HCK,HMGB1,IL1B,ITGA2,ITGAV,LMAN2,MBL2,MERTK,MFGE8,MYO18A,NCKAP1L,PPARG,PRKCG,PTEN,PTX3,PYCARD,RAB27A,RAP1A,RAPGEF1,SCARB1,SLC11A1,SPACA3,STAP1,SYK,SYT11,SYT7,TGFB1,TLR2,TNF,TUB,TULP1	TetrapodAncestor	117.691
GO.Biological.Process	GO:0071229	cellular.response.to.acid.chemical	269	3.082814e-122	3.982071e-118	1.480324e-120	1.279082e+0	ABCA1,ABCB4,ABL2,ACACA,ADNP2,AKAP8,APOB,AQP1,AQP2,AVPR1A,BCL11A,BCL2L1,BRINP1,BRINP2,BRINP3,CAPN2,CASTOR1,CCL2,CCNB1,CDK4,CEBPB,CLDN1,COL16A1,COL1A1,COL1A2,COL3A1,COL5A2,COL6A1,CPEB1,CPEB4,CPS1,CPT1A,CREB1,CYBA,CYBB,CYP26B1,DGAT2,DNMT3A,E2F1,EDN1,EGFR,EGR1,EPHA3,FFAR2,FFAR3,FGFR2,FZD10,FZD4,FZD7,GCLM,GJB3,GLRA1,GLRA2,GNG2,HAMP,HDAC2,HNRNPD,HSF1,HTRA2,ID3,IPO5,KCNK4,KCNMB1,KLF4,KRT13,LAMTOR2,LAMTOR3,LAMTOR4,LARS,LDLR,LEP,LTK,LYN,MTOR,MYB,MYOG,NEURL1,NFATC4,NME1,NME2,NR1H4,NTRK2,NTRK3,OPA1,OR51E2,OSR1,P2RY4,P2RY6,PAX2,PCK1,PDGFB,PDGFC,PDGFD,PDK3,PID1,PINK1,PKD2,PPARG,PPARGC1A,PRKAA1,PRKAA2,PRKCE,PTAFR,PTGDR,PTGER2,PTGER4,PTGFR,PTK2B,PTK7,RARA,RARG,RET,RORB,RPTOR,RRAGA,RRAGD,SESN2,SESN3,SETX,SFRP1,SH3BP4,SHMT1,SIPA1,SLC38A9,SLC6A4,SMARCD1,SNRNP70,SNW1,SOCS1,SOX9,SPAAR,SRC,SREBF1,STRA8,T,TBX1,TEAD2,TESC,TNC,TNF,TWF2,UBR1,UBR2,UCP1,WNT10B,WNT11,WNT3,WNT3A,WNT5A,WNT6,WNT7B,WNT8B,WNT9A,WNT9B,XBP1,XRCC5,YES1,ZC3H12A,ZEB1	TetrapodAncestor	117.4
GO.Biological.Process	GO:0048608	reproductive.structure.development	270	4.784449e-121	6.180073e-117	2.288916e-119	1.185538e+0	ABCB4,ACVR2A,ADA,ADAM15,ADAMTS1,ADCYAP1,ADGRG1,AFP,AGO4,ALKBH1,ALOX15B,AMH,AMHR2,ANKRD7,ANXA1,AR,ARID1A,ARID4A,ARID5B,ARRB1,ARRB2,ASB1,ASCL2,ASH1L,ASPM,ATM,AXL,BAK1,BASP1,BAX,BCL2,BCL2L1,BCL2L11,BCL2L2,BCL2L2-PABPN1,BIK,BIRC2,BIRC6,BMP15,BMP4,BMP5,BMP6,BMP7,BMPR1B,BMPR2,BRIP1,BSG,CASP2,CASP8,CBL,CCDC182,CCND1,CCNF,CDKN1B,CDKN1C,CEBPA,CEBPB,CHD7,CITED1,COL9A3,CRIP1,CSDE1,CTNNA1,CTNNB1,CTSB,CUL7,CYP19A1,CYP27B1,CYR61,DCANP1,DCN,DHCR24,DLG1,DLX3,DMC1,DMRT1,DMRTA1,DNAJB6,E2F7,E2F8,EGFR,EGLN1,EIF2B4,EIF2B5,EIF2S2,EOMES,EPAS1,EPOR,ERCC1,EREG,ESR1,ETNK2,FANCA,FANCF,FANCG,FBXW8,FEM1B,FGF10,FGF9,FGFR2,FKBP4,FNDC3A,FOSL1,FOXA1,FOXC1,FOXF2,FRS2,FSHB,FSHR,FSTL3,FZD4,FZD5,GATA2,GATA3,GATA4,GATA6,GCM2,GGNBP2,GHSR,GJA1,GJB3,GJB5,GLI2,GLI3,GPR149,GRB2,GRHL2,H3F3A,HAND1,HES1,HEY1,HEY2,HIF1A,HMGB2,HMGCS1,HS6ST1,HSD17B2,HSD17B3,HSD17B4,HSF1,HSP90AB1,HTRA1,ID4,IGF2,IL10,IMMP2L,ING2,INHA,INHBA,INHBB,INSL6,ITGB8,JUNB,KDM5A,KDM5B,KIF18A,KISS1,KITLG,KLHL32,KMT2B,KRT19,LDOC1,LEF1,LEP,LFNG,LGR4,LHB,LHCGR,LHX1,LHX4,LHX8,LIF,LRP6,LRRC6,MAMLD1,MAP3K4,MAPK1,MAPK14,MAS1,MC2R,MDFI,MEA1,MEN1,MERTK,MGST1,MKKS,MMP14,MMP19,MSH2,MSH4,MYOCD,NASP,NCOA1,NCOA4,NDP,NEUROG1,NIPBL,NKX3-1,NOBOX,NOG,NOS3,NOTCH1,NR0B1,NRIP1,NSDHL,NTRK1,NUDT1,NUP107,NUP210L,NUPR1,OSR1,OVOL2,PATZ1,PCDH12,PCYT1B,PDGFB,PDGFRB,PGR,PHLDA2,PITX2,PKD1,PKD2,PLAC1,PLAG1,PLCD3,PLEKHA1,PLG,PLK4,PPARD,PPARG,PRDM1,PRDX3,PRDX4,PRKACG,PSAP,PSAPL1,PTCH1,PTEN,PTGIS,PTK2,PTPN11,RAB13,RAD21L1,RARA,RARG,RBP4,RBPJ,RDH10,REC8,REN,RHOBTB3,RNF38,ROBO2,ROR2,RPS6,RSPO3,RXFP2,RXRA,SAFB2,SCX,SERPINA5,SERPINB5,SERPINE2,SETD2,SFRP1,SFRP2,SGPL1,SIRT1,SLIT2,SLIT3,SMAD4,SMARCC1,SNAI1,SOCS3,SOD1,SOHLH1,SOX15,SOX8,SOX9,SPINT1,SPO11,SPP1,SRC,SRD5A1,SRD5A2,ST14,STAR,STC1,STC2,STK4,STOX2,STRA6,SYCP2,TAF4,TBC1D20,TBX3,TCF21,TESC,TEX11,TEX15,TFAP2C,TFEB,TGFB2,TGFBR1,TIFAB,TIPARP,TLR3,TLR5,TMED2,TNC,TNFSF10,TP63,TRIM28,TSPY2,TTPA,TYRO3,UBE3A,VASH1,VASH2,VDR,VEGFA,WDR77,WNT4,WNT5A,WNT7A,WNT7B,WNT9B,YBX3,ZFAT,ZFP36L1,ZFP42,ZFPM2,ZNF830	TetrapodAncestor	116.209
GO.Biological.Process	GO:0001763	morphogenesis.of.a.branching.structure	271	1.463698e-120	1.890659e-116	6.976600e-119	1.250704e+0	ADAMTS16,AR,AREG,B4GALT1,BCL2,BMP2,BMP4,BMP7,BTRC,CASR,CCL11,CELSR1,CITED1,COL13A1,CSF1,CTNNB1,CTSH,CTSZ,DCHS1,DDR1,DLG1,DLG5,DLL4,DRD2,EDN1,EGF,ENG,EPHA2,EPHA7,ESR1,ESRP2,EYA1,FAT4,FEM1B,FGF1,FGF10,FGF2,FGF7,FGFR1,FGFR2,FOXA1,FOXC2,FOXF1,FRS2,FZD5,GBX2,GDF2,GDNF,GLI2,GLI3,GNA13,GPC3,GRB2,GREM1,GRHL2,GZF1,HHEX,HNF1B,IHH,IL10,IL6,KDM5B,KRAS,LAMA5,LEF1,LHX1,LRP5,MET,MKS1,MMP14,MSX2,MYC,MYCN,NFATC4,NKX3-1,NOG,NOTCH1,NOTCH4,NRP1,PAK1,PAX2,PAX8,PBX1,PGR,PITX2,PKD1,PKD2,PLXNA1,PLXND1,PML,PRDM1,PROX1,PTCH1,RASIP1,RDH10,RERE,RSPO2,RSPO3,SEMA3A,SEMA3C,SEMA3E,SETD2,SFRP1,SFRP2,SLIT2,SMAD4,SOCS3,SOX10,SOX8,SOX9,SPINT1,SPRY1,SPRY2,SRC,SRF,ST14,STK4,TBX20,TBX3,TCF21,TDGF1,TGFB1,TGFBR2,TGM2,TIMELESS,TNC,TP63,VANGL2,VDR,VEGFA,WNT1,WNT4,WNT5A,WNT6,WNT9B	TetrapodAncestor	115.723
GO.Biological.Process	GO:1901988	negative.regulation.of.cell.cycle.phase.transition	272	3.114113e-120	4.022500e-116	1.478860e-118	1.356785e+0	APC,ATF5,ATM,AURKA,AURKB,BAX,BCL2,BRCA1,BTG2,BUB1,C10orf99,CARM1,CASP2,CCNB1,CCND1,CDC25C,CDC73,CDK1,CDK2,CDK2AP2,CDKN1A,CDKN1B,CDKN2B,CDKN2D,CENPF,CENPJ,CHEK2,CHMP4C,CNOT1,CNOT10,CNOT11,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT8,CRADD,CTDSP1,CTDSP2,CTDSPL,CUL1,DACT1,DCUN1D3,DONSON,E2F1,E2F4,E2F7,E2F8,EP300,EZH2,FANCI,FBXL7,FBXO31,FBXO7,FOXN3,FOXO4,GADD45A,GIGYF2,GJC2,GML,GPNMB,GPR132,GTSE1,H2AFY,HMGA2,HUS1,HUS1B,IK,JADE1,KANK2,KLHL22,MAD1L1,MAD2L1,MAD2L2,MDM2,MDM4,MEN1,MIIP,MOS,MRE11,MRNIP,MUC1,MUS81,MYO16,NAE1,NBN,NOP53,NPM1,ORAOV1,OVOL1,PCBP4,PCNA,PIDD1,PINX1,PKD2,PLAGL1,PLK1,PLK2,PLK3,PML,PRKDC,PRMT1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTEN,RAD17,RAD21,RB1,RFWD3,RGCC,RPA2,RPS27A,RPS27L,SFN,SLFN11,SMARCA4,SOX4,SUSD2,TEX14,TFDP2,TICRR,TNKS1BP1,TOPBP1,TP53,TP63,TP73,TPR,TPRA1,TRIAP1,TRIP13,TTK,UBC,USP47,VPS4A,ZFP36L1,ZFP36L2,ZFYVE19,ZNF207,ZNF385A,ZNF830,ZW10	TetrapodAncestor	115.396
GO.Biological.Process	GO:0060412	ventricular.septum.morphogenesis	273	4.181772e-120	5.401595e-116	1.978606e-118	1.481690e+0	BMP4,BMPR2,CITED2,EGLN1,FGFR2,FGFRL1,FZD1,FZD2,HES1,HEY1,HEY2,HEYL,NKX2-5,NOG,NOTCH1,NSD2,PITX2,PROX1,SMAD4,SMAD7,SOX11,SOX4,TBX3,TGFB2,TGFBR1,TGFBR2,VANGL2,WNT11,WNT5A,ZFPM1,ZFPM2	TetrapodAncestor	115.267
GO.Biological.Process	GO:0060828	regulation.of.canonical.Wnt.signaling.pathway	274	4.565644e-120	5.897442e-116	2.152351e-118	1.252130e+0	AES,AMER1,AMER2,AMER3,ANKRD10,ANKRD6,APC,APC2,APOE,ARNTL,ASPM,AXIN2,BAMBI,BICC1,BMP2,BTRC,CAPRIN2,CAV1,CCAR2,CDH2,CDK14,CHD8,COL1A1,CSNK1A1,CSNK1D,CTNND1,CTNND2,CUL3,DAB2,DAB2IP,DACT1,DACT3,DAPK3,DDX3X,DIXDC1,DKK1,DKK2,DKK3,DKK4,DLX5,DRAXIN,DVL1,DVL3,EDA,EGR1,FERMT1,FGF10,FGF9,FGFR2,FOXO1,FUZ,FZD5,FZD6,FZD9,GLI3,GPC3,GPRC5B,GREM1,GSK3A,GSKIP,HDAC1,HECW1,IFT20,IGFBP2,IGFBP4,IGFBP6,ISL1,JADE1,JUP,KLHL12,KREMEN1,KREMEN2,LATS1,LATS2,LEF1,LGR4,LGR5,LGR6,LIMD1,LRP4,LRP5,LRP6,LRRK2,MAD2L2,MAPK14,MCC,MESP1,MKS1,MLLT3,NAIP,NFKB1,NKD2,NKX2-5,NLE1,NOG,NOTCH1,NOTUM,NPHP3,NPHP4,PFDN5,PIN1,PPP1CA,PRICKLE1,PRKN,PSEN1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTPRO,RAPGEF1,RBMS3,RBPJ,RNF146,RNF220,ROR2,RPS27A,RSPO1,RSPO2,RSPO3,SCEL,SCYL2,SDHAF2,SFRP1,SFRP2,SFRP4,SFRP5,SIAH2,SMURF2,SNAI2,SOST,SOSTDC1,SOX10,SOX17,SOX2,SOX4,SOX7,SOX9,SRC,STK4,SULF2,TBX18,TLE2,TMEM131L,TMEM64,TNKS,TNKS2,TNN,TRPM4,UBC,UBR5,VPS35,WLS,WNT1,WNT10B,WNT11,WNT3A,WNT4,WNT5A,WNT7A,WWTR1,XIAP,ZBED3,ZNF703,ZNRF3	TetrapodAncestor	115.229
GO.Biological.Process	GO:0032103	positive.regulation.of.response.to.external.stimulus	275	1.087318e-119	1.404489e-115	5.107231e-118	1.255605e+0	ADAM8,ADORA2B,AGER,AGT,AGTR1,AIF1,ANKRD17,ANO6,APOH,ARG1,ARTN,BMP6,BMPR2,BRAF,BTK,C1QBP,C3,C3AR1,CALR,CAMK1D,CASR,CCL1,CCL19,CCL2,CCL21,CCL3,CCL4,CCL5,CCL7,CCR1,CCR2,CCR4,CCR6,CCR7,CD180,CD28,CD47,CD6,CD74,CDH13,CDK19,CMKLR1,CNR1,CNTF,CPB2,CREB3,CREB3L3,CSF1,CX3CL1,CXCL1,CXCL10,CXCL11,CXCL13,CXCL14,CXCL2,CXCL3,CXCL5,CXCL6,CXCL8,CXCL9,CYBA,CYP27B1,DAPK2,DDT,DDX60,DHX9,DSCAM,EDN1,EDN2,EDN3,EGFR,ENSG00000173366,ETS1,F12,F2,F2RL1,F3,F7,FABP4,FCER1G,FFAR2,FFAR3,FGF10,FGF16,FGF18,FGF2,FGFR1,FKBP1B,GAS6,GHSR,GPRC5B,GPSM3,HAVCR2,HMGB1,HRG,HSPB1,IDO1,IL12A,IL12B,IL15,IL16,IL17A,IL17B,IL17F,IL17RA,IL17RB,IL17RC,IL18,IL1B,IL1RL1,IL2,IL21,IL23A,IL33,IL4,IL6,IL6R,IL6ST,ITGA2,JAK2,KARS,KLKB1,LBP,LDLR,LGALS9,LPAR1,LPL,LRSAM1,LY86,LY96,MAPK13,MAPK14,MAPK3,MEGF8,MET,MGST2,MIF,MOSPD2,NCKAP1L,NDEL1,NLRP10,NOD1,NPY,NPY5R,NRP1,NTF3,NTRK3,OPRM1,OPTN,OSM,OSMR,P2RX4,PARK7,PDE2A,PDGFB,PDGFD,PDGFRB,PF4,PF4V1,PGC,PIK3CG,PLA2G2A,PLA2G7,PLG,PPBP,PPM1F,PRKCA,PRKD1,PRKD2,PTGER3,PTGER4,PTK2B,RAC1,RAC2,RARRES2,RIPK2,RIPOR2,S100A12,S100A14,S100A7,S100A8,S100A9,S1PR1,SASH1,SCG2,SEMA5A,SLIT2,SNCA,SNW1,SNX4,STX3,STX4,TAC1,TBK1,TGFB1,TGM2,THBD,THBS1,THBS4,TIAM1,TICAM1,TIRAP,TLR10,TLR2,TLR3,TLR4,TLR6,TLR9,TNF,TNFRSF11A,TNFRSF1A,TNFSF11,TNFSF14,TNFSF18,TNIP1,TRAF6,TUBB2B,UNC13B,USF1,VAMP8,VEGFA,VEGFB,VEGFC,VEGFD,WNT5A,XCL1,ZNF580,ZP3	TetrapodAncestor	114.852
GO.Biological.Process	GO:2000134	negative.regulation.of.G1/S.transition.of.mitotic.cell.cycle	276	3.015994e-119	3.895759e-115	1.411507e-117	1.503466e+0	ATM,AURKA,BAX,BCL2,BTG2,CARM1,CASP2,CCNB1,CCND1,CDC25C,CDC73,CDK1,CDK2,CDK2AP2,CDKN1A,CDKN1B,CDKN2B,CENPJ,CHEK2,CNOT1,CNOT10,CNOT11,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT8,CRADD,CTDSP1,CTDSP2,CTDSPL,DACT1,DCUN1D3,E2F1,E2F4,E2F7,E2F8,EP300,EZH2,FBXO31,FBXO7,GADD45A,GIGYF2,GJC2,GML,GPNMB,GTSE1,JADE1,KANK2,MDM2,MDM4,MUC1,MYO16,NPM1,PCBP4,PCNA,PIDD1,PKD2,PLAGL1,PLK2,PLK3,PML,PRKDC,PRMT1,PTEN,RB1,RFWD3,RGCC,RPA2,RPS27A,RPS27L,SFN,SLFN11,SMARCA4,SOX4,TFDP2,TNKS1BP1,TP53,TP63,TP73,TRIAP1,UBC,ZNF385A	TetrapodAncestor	114.409
GO.Biological.Process	GO:0071901	negative.regulation.of.protein.serine/threonine.kinase.activity	277	3.543108e-119	4.576633e-115	1.652214e-117	1.388025e+0	ABL1,ADIPOQ,AIDA,APC,APOE,BMP4,BMP7,CASP3,CAV1,CAV3,CBLC,CD300A,CDK5RAP1,CDKN1A,CDKN1B,CDKN1C,CDKN2A,CDKN2B,CDKN2C,CDKN2D,CEBPA,CHORDC1,CIB1,DAB2IP,DNAJA1,DTNBP1,DUSP1,DUSP10,DUSP16,DUSP18,DUSP19,DUSP2,DUSP21,DUSP22,DUSP3,DUSP6,DUSP7,DUSP8,DUSP9,FAM212A,FAM212B,FBXO7,GBA,GPS1,GSTP1,H2AFY,HEXIM1,HEXIM2,HHEX,HMGCR,HSPB1,IL1B,INCA1,INPP5K,IRAK3,KAT2B,LATS1,LATS2,LAX1,LRP5,LRP6,LYN,MAPK8IP1,MBIP,MEN1,MYOCD,NF1,NUP62,PKIA,PKIB,PKIG,PLK1,PRKAG2,PRKAR1A,PRKAR1B,PRKAR2B,PRKCD,PTEN,PTPN1,PTPN22,PTPRJ,PYCARD,RGS14,RGS2,RGS3,RGS4,RPTOR,SERPINB3,SFN,SFRP1,SFRP2,SIRT1,SMPD1,SORL1,SPRED1,SPRED2,SPRY1,SPRY2,STK38,TNFAIP3,TP73,UCHL1,WEE2,WNK1,YWHAG,ZNF675	TetrapodAncestor	114.339
GO.Biological.Process	GO:1901652	response.to.peptide	278	5.017237e-119	6.480765e-115	2.331210e-117	1.203504e+0	AANAT,ABCB4,ABCC8,ADCY2,ADCY3,ADCY4,ADCY5,ADCY8,ADIPOQ,ADRB2,AGER,AGRP,AGT,AGTR1,AGTR2,AGTRAP,AHCYL1,AKR1B1,AKT2,ANXA1,AP3S1,APC,APEX1,APOBEC1,APP,APPL1,AREG,ARG1,ARHGEF2,ARID1B,ATP6AP1,ATP6V0A4,ATP6V0B,ATP6V0C,ATP6V0D1,ATP6V0D2,ATP6V0E1,ATP6V0E2,ATP6V1B1,ATP6V1B2,ATP6V1C1,ATP6V1C2,ATP6V1D,ATP6V1E1,ATP6V1E2,ATP6V1G1,ATP6V1G3,ATP6V1H,AVPR1A,AVPR1B,AVPR2,BAIAP2L2,BCAR1,BMP7,BRAF,BRIP1,BSG,BTG2,C2CD5,CA2,CACNA1A,CACNA2D1,CACNB1,CACYBP,CAMK2A,CAPN10,CASP4,CASR,CAT,CAV1,CAV2,CCKAR,CCL2,CCNA2,CD36,CD40,CDC5L,CDC6,CDK4,CDK5,CDKN1B,CDO1,CFLAR,CITED1,COL1A1,CPEB1,CPEB2,CPS1,CREB1,CRHBP,CRHR1,CRHR2,CRK,CRY1,CSH1,CSK,CTGF,CYBA,CYBB,CYC1,CYFIP1,DDX11,DENND4C,EDN1,EEF2K,EGR1,EGR2,EIF2B1,EIF2B3,EIF2B4,EIF2B5,EIF4EBP1,EIF6,ENPP1,ENSG00000278139,EPHA4,EPM2AIP1,EREG,ERRFI1,F7,FABP3,FER,FGF21,FIS1,FOXC2,FOXO1,FOXO4,GAB1,GAL,GCGR,GCK,GGH,GH1,GH2,GHR,GHRHR,GHSR,GIP,GJA1,GLP1R,GLP2R,GNAI1,GNB2,GNG10,GNG11,GNG12,GNG13,GNG2,GNG3,GNG7,GNG8,GNRH1,GNRHR,GOT1,GPER1,GPLD1,GPR22,GRB2,GRM5,GSK3A,GSTP1,HADHA,HCRTR1,HCRTR2,HDAC5,HDAC9,HHEX,HSD11B2,HSF1,ID1,IDE,IGF1,IGF1R,IGF2,IGFBP5,IL10,IL6,INAVA,INHBB,INPP5K,INS,INSIG2,IQGAP1,IRS1,IRS2,IRS4,JAG1,JAK2,JAK3,KAT2B,KAT7,KHK,KL,KLF1,KLF10,KLF11,KLF15,KLF2,KLF3,KLF4,KLF5,LEP,LPIN1,LRP1,LRP5,LRP6,LYN,MAPK1,MAPK14,MAPK3,MAS1,MAX,MC4R,MDM2,MEN1,MGARP,MTOR,NDEL1,NEFL,NFKB1,NGFR,NKX6-1,NLRP1,NME2,NOD1,NOTCH1,NPFFR2,NR4A1,NR4A2,NR4A3,OGT,OPRK1,OTC,OXT,OXTR,PAK1,PARP1,PCK1,PDK2,PDPK1,PFKFB1,PHEX,PHIP,PIK3C2A,PIK3CA,PIK3R1,PIK3R2,PIK3R3,PKLR,PKM,PLA2G1B,PLN,PNPT1,POR,PPARA,PPARG,PRKACA,PRKACG,PRKAR1A,PRKAR1B,PRKAR2B,PRKCD,PRKCI,PRKCZ,PRKDC,PRL,PRLH,PRLR,PSEN1,PTEN,PTK2,PTPN1,PTPN22,PTPRA,PXN,QDPR,QRFPR,RAB13,RAB31,RAB8A,RAP1B,RBBP4,RELA,RETN,RHOQ,RIPK2,RNF40,RPE65,RPL23,SESN2,SESN3,SH2B2,SHC1,SIRT1,SLC25A33,SLC27A1,SLC2A1,SLC2A8,SLC30A10,SLC34A1,SLC9A1,SMARCC1,SOCS2,SOCS7,SOGA1,SORBS1,SOS1,SP1,SRC,SRD5A1,SRD5A2,SREBF1,SRSF4,SRSF5,SRSF6,STAR,STAT1,STC2,STXBP4,TBC1D4,TCIRG1,TEK,TFF1,TGFB1,TH,TIMELESS,TIMP1,TIMP4,TLR2,TLR4,TLR6,TNFAIP3,TNFSF10,TP53,TRIB3,TRPV1,TSHR,TUSC5,UCP2,UCP3,UMODL1,UPRT,USF1,VAMP2,WDTC1,WNT1,XBP1,YWHAG,ZFP36L1,ZNF106	TetrapodAncestor	114.188
GO.Biological.Process	GO:0006974	cellular.response.to.DNA.damage.stimulus	279	2.058507e-118	2.658973e-114	9.530371e-117	1.178012e+0	AATF,ABL1,ACD,ACTR5,ACTR8,AEN,ALKBH1,ALKBH3,ALKBH7,ALKBH8,ANKLE1,AP5S1,APC,APEX1,APLF,APTX,ASCC1,ASCC2,ASCC3,ASF1A,ASH2L,ASTE1,ATAD5,ATM,ATMIN,ATP23,ATR,ATXN3,AURKA,BABAM1,BABAM2,BACH1,BAD,BAG6,BAK1,BARD1,BAX,BAZ1B,BCL2,BCL2A1,BCL2L1,BCL2L10,BCL2L11,BCL2L2,BCL2L2-PABPN1,BCL3,BCL6,BID,BIVM-ERCC5,BOD1L1,BRAT1,BRCA1,BRCC3,BRD4,BRIP1,BRSK1,BTG2,C21orf2,C7orf49,CARM1,CASP2,CASP3,CASP9,CBL,CCAR2,CCDC13,CCDC155,CCNB1,CCND1,CCNH,CCNK,CCNO,CDC14B,CDC25C,CDC45,CDC5L,CDCA5,CDIP1,CDK1,CDK2,CDK7,CDK9,CDKN1A,CDKN1B,CDKN2AIP,CDKN2D,CENPJ,CENPS,CENPX,CEP164,CEP63,CHAF1A,CHAF1B,CHCHD6,CHD1L,CHD2,CHEK1,CHEK2,CIB1,CIDEB,CINP,CNOT1,CNOT10,CNOT11,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT8,COPS2,COPS3,COPS4,COPS7B,COPS8,CRADD,CRIP1,CRY1,CSNK1E,CTLA4,CUL4A,CUL5,DCLRE1B,DCLRE1C,DDB1,DDB2,DDIT4,DDX1,DDX11,DDX39A,DMAP1,DMC1,DNA2,DNAJA1,DONSON,DOT1L,DTX3L,DYRK2,E2F1,E2F4,E2F7,E2F8,EEPD1,EGLN3,EID3,EIF2AK4,EME1,EME2,EMSY,ENDOV,ENSG00000254469,ENSG00000256514,ENSG00000268361,EP300,EPHA2,ERCC1,ERCC2,ERCC3,ERCC4,ERCC5,ERCC6,ERCC6L2,ERCC8,ESCO2,ETAA1,EXD2,EXO1,EXO5,EYA1,EYA2,EYA3,EYA4,FAAP20,FAAP24,FAN1,FANCA,FANCB,FANCC,FANCE,FANCF,FANCG,FANCI,FANCL,FANCM,FBXO18,FBXO31,FBXO45,FBXO6,FEN1,FMN2,FMR1,FOXM1,FOXN3,FOXO1,FOXO4,FZR1,GADD45A,GEN1,GGN,GIGYF2,GINS2,GINS4,GML,GNL1,GPS1,GRB2,GTF2H1,GTF2H2,GTF2H2C,GTF2H3,GTF2H4,GTF2H5,GTSE1,H2AFX,HELB,HERC2,HIC1,HINFP,HIPK1,HIPK2,HIST1H4J,HIST1H4K,HIST1H4L,HIST2H4B,HIST4H4,HMGA2,HMGB1,HMGB2,HMGN1,HMOX1,HPF1,HSF1,HTRA2,HUS1,HUS1B,IGHMBP2,IKBKE,IKBKG,IMMP2L,INIP,INO80,INO80B,INO80D,INO80E,INTS3,IRF3,IRF7,ISG15,ISY1,JMY,KAT5,KDM2A,KDM4D,LIG3,LIG4,LYN,MACROD1,MACROD2,MAD2L2,MAEL,MAP2K6,MAPK1,MAPK14,MAPK3,MAPKAPK2,MARF1,MASTL,MB21D1,MC1R,MCM10,MCM7,MCM8,MCM9,MCRS1,MCTS1,MDC1,MDM2,MDM4,MEIOC,MEN1,METTL3,MGME1,MIF,MLH1,MMS19,MMS22L,MND1,MORF4L1,MORF4L2,MPG,MRE11,MRNIP,MRPS11,MRPS26,MRPS35,MRPS9,MSH2,MSH3,MSH4,MSH6,MTA1,MTOR,MUC1,MUS81,MUTYH,MYC,MYO6,NABP1,NBN,NCOA6,NDRG1,NEIL1,NEIL2,NEIL3,NEK1,NEK11,NEK4,NEXMIF,NFATC2,NFATC4,NFRKB,NHEJ1,NIPBL,NOP53,NPAS2,NPM1,NSD2,NSMCE1,NSMCE2,NSMCE3,NSMCE4A,NTHL1,NUAK1,NUCKS1,NUDT1,NUPR1,NUPR2,OGG1,ORAOV1,OTUB1,PAGR1,PALB2,PAPD7,PARK7,PARP1,PARP2,PARP3,PARP4,PARP9,PARPBP,PAXIP1,PAXX,PCBP4,PCLAF,PCNA,PEA15,PGAP2,PHF1,PIAS4,PIDD1,PIF1,PIK3R1,PITHD1,PLAGL1,PLK1,PLK2,PLK3,PMAIP1,PML,PMS1,PNKP,POLB,POLD1,POLD2,POLD3,POLD4,POLE,POLE2,POLG2,POLH,POLI,POLK,POLL,POLM,POLN,POLQ,POLR2A,POLR2B,POLR2C,POLR2D,POLR2F,POLR2G,POLR2H,POLR2I,POLR2J,POLR2L,PPIE,PPP1R15A,PPP5C,PRIMPOL,PRKDC,PRMT1,PRMT6,PRPF19,PSEN1,PTPN11,PTTG1,PYCARD,RAD1,RAD17,RAD18,RAD21,RAD21L1,RAD23A,RAD23B,RAD50,RAD51,RAD51AP1,RAD51B,RAD51C,RAD51D,RAD52,RAD54L,RAD9A,RBBP5,RBBP8,RBM14,RBM17,RCHY1,REC8,RECQL,RECQL4,RECQL5,REV1,RFC2,RFC3,RFC4,RFWD3,RGCC,RHNO1,RIF1,RMI1,RMI2,RNASEH2A,RNF138,RNF168,RNF169,RNF8,RPA2,RPA3,RPA4,RPAIN,RPS27A,RPS27L,RPS3,RPS6KA6,RRM2B,RUVBL1,RUVBL2,SESN2,SETD2,SETD7,SETMAR,SETX,SFN,SFPQ,SGK1,SIRT1,SIRT4,SIRT6,SLC30A9,SLF1,SLF2,SLX1A,SLX1B,SLX4,SMARCAD1,SMARCAL1,SMARCB1,SMC1A,SMC5,SMC6,SMG1,SNW1,SOX4,SP100,SPATA18,SPATA22,SPDYA,SPIDR,SPO11,SPRTN,SSRP1,STUB1,STXBP4,SUMO1,SUMO2,SUMO3,SUPT16H,SUSD6,SWI5,SWSAP1,SYCP1,TAF1,TAF9,TAOK1,TAOK2,TCEA1,TDG,TDP1,TDP2,TERF2,TERF2IP,TEX12,TEX15,TFDP2,TFDP3,TFIP11,TFPT,TICRR,TIGAR,TIMELESS,TIPRL,TLK2,TMEM109,TMEM189-UBE2V1,TNF,TNFRSF1A,TNFRSF1B,TNKS1BP1,TNP1,TONSL,TOP2A,TOP3A,TOPBP1,TOPORS,TP53,TP63,TP73,TRAF6,TREX2,TRIAP1,TRIM25,TRIM28,TRIP12,TRIP13,TRRAP,TTC5,UBA1,UBA6,UBA7,UBC,UBE2A,UBE2D3,UBE2E2,UBE2I,UBE2L6,UBE2N,UBE2T,UBE2V1,UBE2V2,UBE2W,UBR5,UCHL5,UFD1,UHRF1,UIMC1,UNG,UPF1,USP1,USP10,USP16,USP28,USP3,USP47,USP7,UVRAG,UVSSA,VAV3,VCP,WDR33,WDR76,WNT1,WRN,WRNIP1,XAB2,XIAP,XPA,XPC,XRCC1,XRCC2,XRCC4,XRCC5,XRCC6,YAP1,YY1,ZBTB1,ZBTB38,ZBTB40,ZC3H12A,ZDHHC16,ZFYVE26,ZMAT3,ZNF385A,ZNF830,ZRANB3	TetrapodAncestor	113.575
GO.Biological.Process	GO:0045667	regulation.of.osteoblast.differentiation	280	5.274570e-118	6.813162e-114	2.433272e-116	1.323483e+0	ACVR2A,ACVR2B,AREG,ATP6AP1,ATRAID,AXIN2,BMP2,BMP4,BMP6,BMP7,BMPR1A,BMPR1B,BMPR2,CDK6,CEBPA,CEBPB,CEBPD,CHRD,CITED1,CTNNB1,CYR61,DDR2,DDX5,ESRRA,FAM20C,FBN2,FGF23,FGFR2,GDF10,GDF2,GDPD2,GLI3,GNAS,GREM1,HAND2,HDAC4,HDAC7,HDAC8,HGF,ID1,ID3,ID4,IFITM1,IGF1,IGFBP5,IL6,IL6R,IL6ST,JAG1,LIMD1,LRP5,MEF2C,MEN1,MSX2,NBR1,NELL1,NOCT,NOG,NOTCH1,NPPC,OSTN,PDLIM7,PIAS2,PRKACA,PRKD1,PTCH1,PTK2,RANBP3L,RASSF2,RIOX1,RORB,RUNX2,SEMA4D,SFRP1,SFRP2,SKI,SMAD5,SMOC1,SNAI2,SOX11,SUCO,SUFU,TMEM64,TNF,TNN,TP63,TRPM4,TWIST1,TWIST2,UCMA,WNT10B,WNT4,WNT7B,ZHX3	TetrapodAncestor	113.167
GO.Biological.Process	GO:0042129	regulation.of.T.cell.proliferation	281	9.198798e-118	1.188209e-113	4.228501e-116	1.360695e+0	AGER,AIF1,ANXA1,ARG1,ARG2,BMP4,CARD11,CASP3,CCDC88B,CCL19,CCL5,CCR2,CD1D,CD209,CD24,CD274,CD276,CD28,CD3E,CD46,CD55,CD59,CD6,CD80,CD86,CEBPB,CLC,CLEC4G,CLECL1,CORO1A,CTLA4,CTNNB1,DHPS,DLG1,DLG5,DNAJA3,EBI3,EFNB1,EPO,ERBB2,FADD,FOXJ1,FOXP3,GNRH1,GPAM,GPNMB,HAVCR2,HES1,HHLA2,HMGB1,IDO1,IFNG,IGF1,IGF2,IGFBP2,IHH,IL10,IL12A,IL12B,IL12RB1,IL15,IL18,IL1B,IL2,IL20RB,IL21,IL23A,IL23R,IL27,IL4,IL6,IL6ST,IRF1,ITCH,JAK3,LEP,LGALS3,LGALS9,LILRB2,LRRC32,MAD1L1,NCK1,NCK2,NCKAP1L,NDFIP1,PAWR,PDCD1LG2,PDE5A,PELI1,PLA2G2D,PLA2G2F,PNP,PRKAR1A,PRKCQ,PYCARD,RAC2,RASAL3,RC3H1,RIPK2,RIPK3,RPS3,SASH3,SCGB1A1,SDC4,SELENOK,SOS1,SPN,SYK,TFRC,TGFB1,TGFBR2,TMEM131L,TMIGD2,TNFRSF13C,TNFRSF14,TNFRSF21,TNFSF13B,TNFSF18,TNFSF9,TRAF6,VCAM1,VSIG4,VTCN1,XCL1,ZAP70,ZP3,ZP4	TetrapodAncestor	112.925
GO.Biological.Process	GO:0032844	regulation.of.homeostatic.process	282	1.520804e-117	1.964423e-113	6.966037e-116	1.185830e+0	ABAT,ABL1,ACD,ACVR1B,ACVR2A,ADA,ADAM8,ADCY5,ADCYAP1R1,ADORA1,ADORA2A,ADRA2A,AGT,AGTR1,AGTR2,AKAP6,ANK2,ANK3,ANKRD54,ANO1,ANXA1,AP3D1,APLN,APLNR,ARRB1,ARRDC3,ATG5,ATM,ATP1A2,ATP6AP1,ATR,AURKB,AVP,AVPR1A,AVPR2,BAD,BAK1,BAX,BCL10,BCL2,BDKRB1,BGLAP,BMP8A,BRSK2,C1QTNF12,C2CD2L,CA2,CA7,CACNA1C,CACNA1G,CALCR,CALM1,CALM2,CALM3,CAMK2D,CARTPT,CASQ1,CASQ2,CATSPER4,CAV1,CAV3,CCK,CCL19,CCL21,CCL3,CCR5,CCR7,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,CD19,CD36,CD38,CD74,CDK16,CDK6,CEMIP,CFTR,CHD7,CHERP,CLDN18,CNR1,CORIN,CORO1A,CSF1R,CSK,CTNNB1,CXCL10,CXCL11,CXCL9,CYBA,DCN,DCP2,DEF8,DHRS7C,DIAPH1,DKC1,DLL1,DMD,DRD1,DRD2,DRD3,EDN1,EDNRB,EFNA5,EGFR,EPHA5,EPO,ERCC1,ERCC4,ERO1A,ETS1,EXOSC10,F2,F2R,F2RL3,FADD,FAM210B,FBXO4,FCER1G,FGF12,FGF2,FGFR4,FKBP1A,FKBP1B,FLCN,FOXA2,FOXO1,FSHB,FZD9,GATA2,GCLM,GNL3,GNL3L,GPAM,GPD1L,GPER1,GPLD1,GPR68,GRIN1,GSTM2,HAP1,HCN4,HDAC8,HIF1A,HMBOX1,HMGB2,HMGCR,HMGN3,HNF4A,HNRNPA2B1,HNRNPC,HNRNPD,HNRNPU,HRC,HSH2D,HSPA9,HTR2A,HTR2B,HTR2C,HTT,IAPP,IBTK,IFI6,IL13,IL1B,IL2,IL20RA,IL6,INHBA,INPP5D,INPP5K,ISG15,ITPKB,ITPR1,ITPR2,ITPR3,JAGN1,JPH1,JPH2,JPH3,JPH4,JSRP1,KIF5B,KITLG,KLF13,LACRT,LCK,LDLR,LEPR,LETM1,LGALS9,LRP5,LRRK2,LYN,MAFB,MAP2K7,MAP3K4,MAP4K4,MAPK1,MAPK14,MAPK15,MAPK3,MAPKAPK5,MC4R,MCOLN1,METRNL,METTL21C,MIF,MLLT11,MLXIPL,MPC2,MRE11,MYC,NAF1,NAT10,NBN,NCKAP1L,NDUFAF2,NEDD4L,NEK7,NEUROD1,NF1,NOL3,NOS1,NPC1,NPFF,NPR1,NPSR1,NR1D1,NR1D2,NR1H2,NR1H3,NR1H4,NR4A3,NRXN1,NTSR1,OPRK1,OXCT1,OXT,P2RX2,P2RX3,P2RX4,P2RX5,P2RX7,PARN,PARP1,PASK,PDE4D,PDPK1,PHPT1,PIF1,PIH1D1,PIK3CD,PIM3,PINK1,PINX1,PKD2,PKIB,PLA2G1B,PLA2G6,PLCG1,PLCG2,PLEKHM1,PLN,PML,PNKP,POT1,PPARGC1A,PPARGC1B,PPP2R3C,PPP3CB,PRKAA1,PRKAA2,PRKACA,PRKCE,PRKCQ,PRKN,PRMT1,PTGER3,PTK2B,PTPN3,RAD50,RALY,RASA3,RBFOX2,RFX6,RIPK3,RYR1,RYR2,RYR3,S1PR1,SCN1B,SCN2B,SCN3B,SCN5A,SELENON,SETD1A,SGIP1,SIDT2,SIGLEC15,SIRT6,SLC22A5,SLC25A23,SLC27A1,SLC30A1,SLC30A10,SLC30A2,SLC30A4,SLC30A5,SLC30A6,SLC30A7,SLC30A8,SLC8A1,SLC8B1,SLC9B2,SLX1A,SLX1B,SLX4,SMAD7,SMAP1,SMARCA4,SMARCB1,SMG1,SMG5,SMG6,SNCA,SPI1,SPP1,SPX,SRC,SREBF2,SRI,STAT1,STX4,STXBP4,SYBU,SYK,TAC1,TAL1,TCP1,TERF1,TERF2,TERF2IP,TFRC,TGFB1,THY1,TIAM1,TINF2,TMBIM6,TMEM27,TMEM64,TNF,TNFAIP3,TNFRSF11A,TNFRSF11B,TNFSF11,TNKS,TNKS2,TPCN1,TPCN2,TRDN,TRIM6,TRPA1,TRPC1,TRPC3,TRPM2,TRPM4,TRPV1,TSC22D4,TSPO,UBASH3B,UBE2C,UBE2S,UCP2,UMOD,UPF1,USP7,UTS2,UTS2R,VSNL1,WNK2,WNK3,XCL1,XRCC1,XRCC5,XRN1,ZFP36,ZFP36L1,ZFPM1,ZNF16	TetrapodAncestor	112.707
GO.Biological.Process	GO:0045088	regulation.of.innate.immune.response	283	9.908376e-117	1.279865e-112	4.522491e-115	1.242905e+0	A2M,ADAM8,ADAR,ANKRD17,AP1G1,APOB,ARG1,ARRB2,BCL10,BIRC2,BIRC3,BPIFB1,BTK,BTRC,C1QBP,CACTIN,CADM1,CARD11,CASP8,CAV1,CCL5,CD14,CD180,CD1D,CD209,CD226,CD300A,CD300LF,CD36,CD86,CD96,CHUK,CLEC12B,CLEC4A,CLEC4C,CLEC4D,CLEC4E,CLEC6A,CLEC7A,CNPY3,COLEC12,CR1,CRK,CRTAM,CTSB,CTSL,CUL1,CYBA,DAB2IP,DCST1,DDX58,DDX60,DHX9,DMBT1,DRD2,DUSP10,ENSG00000173366,EP300,ERAP1,EREG,ESR1,F2RL1,FADD,FAM3A,FBXW11,FCER1G,FCN1,FFAR2,FGG,FGR,FLOT1,GPATCH3,HAVCR2,HCK,HEXIM1,HMGB1,HMGB2,HRAS,HSP90AB1,HSP90B1,ICAM2,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNAR1,IFNAR2,IFNB1,IFNG,IFNGR1,IFNGR2,IFNK,IKBKB,IKBKE,IKBKG,IL12A,IL12B,IL18RAP,IL21,INAVA,INS,IRAK1,IRAK3,IRAK4,IRF1,IRF3,IRF4,IRF7,IRGM,ITCH,ITGAM,ITGB2,JAK2,KLRK1,KRAS,LBP,LEP,LGALS9,LGMN,LGR4,LILRA4,LRRC14,LRRC70,LY96,LYN,MALT1,MAP2K6,MAP3K1,MAP3K7,MAPKAPK2,MAPKAPK3,MARCO,MATR3,MB21D1,MMP12,MUC1,MUC12,MUC13,MUC15,MUC20,MUC3A,MUC4,MUC5AC,MUC5B,MUC6,MUCL1,MUL1,NCR1,NCR3,NECTIN2,NFKB1,NLRC3,NLRC4,NLRC5,NLRP6,NLRX1,NMI,NOD1,NOP53,NR1D1,NR1H2,NR1H3,NR1H4,NRAS,OTUD7A,OTULIN,PAK1,PAK2,PAK3,PARP14,PARP9,PDPK1,PELI1,PGLYRP1,PGLYRP2,PGLYRP3,PGLYRP4,PIAS1,PIK3AP1,PIK3C3,PIK3R6,PLCG2,PLSCR1,POLR3B,POLR3C,POLR3D,POLR3F,PPARG,PQBP1,PRKACA,PRKACG,PRKCD,PRKCE,PRKDC,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PSPC1,PTPN1,PTPN11,PTPN22,PTPRS,PYCARD,RAB7B,RAF1,RASGRP1,RBM14,REG3G,RELA,RELB,RFTN1,RIOK3,RIPK1,RIPK2,RNASEL,RNF125,RNF135,RPS27A,RPS6KA3,RPS6KA5,RSAD2,S100A1,S100A14,S100A8,S100A9,SAMHD1,SARM1,SCRIB,SEC14L1,SERPINB4,SERPINB9,SERPING1,SFPQ,SH2D1A,SH2D1B,SLAMF6,SMPDL3B,SNAI3,SOCS1,SOCS3,SRC,STAT1,STAT2,SUMO1,SYK,TAB1,TAB2,TAB3,TBK1,TICAM1,TICAM2,TIRAP,TKFC,TLR1,TLR10,TLR2,TLR3,TLR4,TLR5,TLR6,TLR9,TMEM173,TMEM189-UBE2V1,TNFAIP3,TNIP1,TNIP2,TNIP3,TRAF3,TRAF6,TRAFD1,TREML4,TRIL,TRIM5,TRIM6,TSPAN6,TXK,TYRO3,UBC,UBE2D1,UBE2D2,UBE2D3,UBE2N,UBQLN1,UFD1,UNC93B1,USP18,VAV1,WDFY1,WNT5A,XIAP,XRCC5,XRCC6	TetrapodAncestor	111.893
GO.Biological.Process	GO:0002062	chondrocyte.differentiation	284	1.389794e-116	1.795197e-112	6.321116e-115	1.381024e+0	AMELX,AXIN2,BMP2,BMP4,BMPR1A,BMPR1B,BMPR2,CHST11,COL11A1,COL27A1,COL2A1,CREB3L2,CYTL1,EIF2AK3,ENSG00000243696,FGF18,FGF9,FGFR1,FGFR3,GDF5,GLI2,GPLD1,HMGA2,IHH,IMPAD1,MAPK14,MATN1,MEF2C,MEF2D,MEX3C,MSX2,MUSTN1,NFIB,NOV,NPPC,OSR1,POC1A,PTH1R,RARG,RUNX1,RUNX2,SCX,SERPINH1,SFRP2,SHOX2,SIX2,SNX19,SOX9,SULF2,TGFB1,TGFBI,TGFBR2,TMEM110-MUSTN1,TRIP11,WNT10B,WNT7A	TetrapodAncestor	111.746
GO.Biological.Process	GO:0042493	response.to.drug	285	2.405409e-116	3.107067e-112	1.090199e-114	1.199238e+0	AACS,ABAT,ABCA1,ABCA2,ABCA3,ABCA8,ABCB4,ABCB5,ABCC2,ABCC8,ABCC9,ABCD3,ABCG2,ACACB,ACER2,ACSL1,ADA,ADCYAP1R1,ADIPOQ,ADORA2A,ADRA1A,ADSSL1,AGPAT2,ALAD,ALDH3A1,AMH,ANKRD1,ANXA1,AOC1,APEX1,APOA1,APOA2,APOBEC1,APOD,AQP1,ARG1,ARRB1,ATG5,ATP1A1,ATP8B1,ATR,BAD,BAK1,BCAR3,BCHE,BCL2,BECN1,BGLAP,BLMH,BRAF,CA9,CALR,CASP3,CAT,CCL2,CCL4,CCNB1,CCND1,CCNO,CD38,CD69,CD86,CDH1,CDH3,CDK1,CDK4,CDK9,CDKN1A,CDKN1B,CENPF,CERS1,CHEK2,CHUK,CLDN1,COL18A1,COL1A1,CPB2,CPS1,CPT1A,CREB1,CRHBP,CTNNB1,CTPS1,CYBA,CYBB,CYP1A1,CYP1A2,CYP2A6,CYP2B6,CYP2C19,CYP2C8,CYP2C9,CYP4B1,DAB1,DAD1,DDC,DHODH,DNMT3A,DNMT3B,DPEP1,DRD1,DRD2,DRD3,DUSP6,DVL3,EDN1,EEF2,EFTUD2,EGFR,EIF2B5,EMX1,EMX2,ENG,F7,FABP3,FBP1,FGF21,FOS,FOSB,FOSL1,FZD1,FZD3,GABRG3,GAL,GAS6,GATA3,GATA4,GATA6,GCLM,GGH,GIP,GNA12,GNAO1,GNAS,GPLD1,GPR52,GRIN2A,HADHA,HDAC2,HDAC4,HDAC5,HMGB2,HMGCS1,HNF1B,HNRNPD,HSD11B2,HSF1,HSP90AB1,HSPA5,HTR1B,HTR2A,HTR2B,HTR2C,IFNG,IGFBP2,IL10,IL1B,IL4,IL6,INHBA,ITGA2,ITGA3,JUN,JUNB,KCNC1,KCNE2,KCNH2,KCNJ11,KCNK3,KCNQ1,LCK,LCN2,LDHA,LGALS1,LOX,LPL,LRP8,LYN,MAOB,MAP2K6,MAS1,MBD1,MCM7,MDK,MDM2,MEF2C,MFSD10,MGST1,MTHFR,MYC,MYO6,NAT8,NCKAP1L,NEUROD1,NFATC2,NKX3-1,NKX6-1,NME1,NNMT,NOS1,NOS2,NPC1,NPC1L1,NPFF,NPPC,NR1I2,NTRK1,NUDT15,OGG1,OR56A1,OR56A4,OR5T3,OTC,OXCT1,OXTR,P2RX7,PAM,PAPD7,PARP4,PAX4,PDE2A,PDE3A,PDE4A,PDE4B,PEMT,PLIN2,PMS1,PNP,POR,PPARG,PPARGC1A,PPM1E,PPM1F,PPOX,PPP1R12A,PPP3CA,PPP3CB,PRKAA2,PRKAR2B,PTCH1,PTEN,PTGR1,PTH,PTK2B,PTN,PTPRM,QDPR,RAD51,RAD54L,RAP1A,RAP1B,RAP2A,RBM22,RECQL5,RELA,REN,REST,RET,RNF149,RPH3AL,RPL18A,RPN2,RPP21,S100A10,SCGB1A1,SEMA3C,SFRP1,SFRP2,SLC12A5,SLC17A3,SLC18A1,SLC19A1,SLC1A2,SLC1A3,SLC22A1,SLC22A12,SLC22A18,SLC22A2,SLC22A3,SLC22A5,SLC26A5,SLC31A1,SLC34A1,SLC46A1,SLC47A1,SLC47A2,SLC6A2,SLC6A3,SLC6A4,SLC8A1,SMPD1,SNCA,SOD1,SORD,SOX10,SPINK4,SRC,SRD5A1,SRD5A2,SREBF1,SRP14,SRP19,SRP54,SRP68,SRR,SS18,SST,STAR,TBXA2R,TERF1,TFAP2B,TFRC,TGFB1,TGFB2,TGFBR2,TGIF1,TH,THBS1,TIMP2,TIMP4,TLR3,TNFRSF11B,TOP1,TP53,TP73,TRPA1,TSPO,TXN2,TXNIP,TYMS,UGT1A1,UMPS,UQCRFS1,USP47,UTS2,UTS2R,VAV3,VEGFB,VEGFC,WFDC1,XPC,XRCC1,XRCC5	TetrapodAncestor	111.508
GO.Biological.Process	GO:0043588	skin.development	286	2.894380e-116	3.738671e-112	1.307227e-114	1.270482e+0	ABCA12,ABCB6,ACER1,ACVR1B,ADAM9,ADAMTS2,ALX4,ANXA1,APCDD1,ARRDC3,ASCL4,ASH1L,ASPRV1,ATP8A2,BCL11B,BCL2,CAPN1,CASP14,CASP3,CD109,CDC42,CDH3,CELA2A,CELSR1,CERS3,CLDN1,CLDN4,CNFN,COL1A1,COL1A2,COL3A1,COL5A1,COL5A2,COL5A3,CSTA,CTNNB1,CYP26B1,DACT2,DHCR24,DKK1,DLL1,DNASE1L2,DSC1,DSC2,DSC3,DSG1,DSG2,DSG3,DSG4,DSP,EDA,EDAR,EGFR,EPHA2,ERCC2,EREG,ERRFI1,EXPH5,FA2H,FGF10,FGF7,FGFR2,FLG,FLG2,FLNB,FOSL2,FOXE1,FOXN1,FOXQ1,FRAS1,FURIN,FUZ,FZD3,FZD6,GBA,GJB3,GNAS,GORAB,GRHL3,HDAC1,HDAC2,HOXC13,HRNR,IFT74,IGFBP5,INHBA,INTU,IRF6,ITGA2,ITGA3,ITGB4,IVL,JAG1,JUP,KAZN,KDF1,KRT1,KRT10,KRT12,KRT13,KRT14,KRT15,KRT16,KRT17,KRT19,KRT2,KRT20,KRT23,KRT24,KRT25,KRT26,KRT27,KRT28,KRT31,KRT32,KRT33A,KRT33B,KRT34,KRT35,KRT36,KRT37,KRT38,KRT39,KRT40,KRT5,KRT6A,KRT6B,KRT6C,KRT7,KRT71,KRT72,KRT73,KRT74,KRT75,KRT76,KRT77,KRT80,KRT81,KRT82,KRT83,KRT84,KRT85,KRT86,KRT9,KRTAP1-1,KRTAP1-5,KRTAP10-1,KRTAP10-10,KRTAP10-11,KRTAP10-12,KRTAP10-2,KRTAP10-4,KRTAP10-5,KRTAP10-6,KRTAP10-7,KRTAP10-8,KRTAP10-9,KRTAP11-1,KRTAP12-1,KRTAP12-3,KRTAP12-4,KRTAP13-1,KRTAP13-3,KRTAP13-4,KRTAP15-1,KRTAP17-1,KRTAP19-1,KRTAP19-5,KRTAP19-8,KRTAP2-1,KRTAP2-2,KRTAP2-3,KRTAP2-4,KRTAP20-2,KRTAP21-1,KRTAP21-2,KRTAP21-3,KRTAP23-1,KRTAP24-1,KRTAP27-1,KRTAP29-1,KRTAP3-1,KRTAP3-2,KRTAP3-3,KRTAP4-1,KRTAP4-11,KRTAP4-2,KRTAP4-4,KRTAP4-5,KRTAP4-6,KRTAP4-7,KRTAP4-8,KRTAP4-9,KRTAP5-1,KRTAP5-2,KRTAP5-3,KRTAP5-5,KRTAP5-6,KRTAP8-1,KRTAP9-1,KRTAP9-2,KRTAP9-6,KRTAP9-7,LAMA5,LATS1,LCE1F,LCE2D,LCE3A,LCE3E,LCE5A,LCE6A,LDB2,LELP1,LGR4,LGR5,LHX2,LIPK,LIPM,LIPN,LOR,LRP4,LTB,MET,NF1,NOTCH1,NSDHL,NSUN2,OVOL1,PALLD,PCSK6,PDGFA,PERP,PI3,PIP5K1A,PKD1,PKP1,PKP2,PKP3,PPHLN1,PPL,PRR9,PRSS8,PSEN1,PTCH2,RBPJ,RELA,RPTN,RYR1,S100A7,SCEL,SFN,SHARPIN,SLC27A4,SLITRK5,SMAD4,SMO,SNAI1,SOS1,SOSTDC1,SOX18,SOX9,SPINK5,SPINK6,SPINK9,SPRR1A,SPRR1B,SPRR2A,SPRR2D,SPRR2F,SPRR2G,SPRR3,SPRR4,SRF,ST14,STK4,STMN1,SUFU,TCF15,TCHH,TFAP2B,TGFB2,TGM1,TGM3,TMEM79,TNFRSF19,TP63,TRPC4AP,TSG101,TXNIP,VANGL2,WNT10A,WNT16,WNT5A,ZDHHC21	TetrapodAncestor	111.427
GO.Biological.Process	GO:0007178	transmembrane.receptor.protein.serine/threonine.kinase.signaling.pathway	287	7.519427e-116	9.712844e-112	3.384266e-114	1.282132e+0	ACVR1B,ACVR2A,ACVR2B,ACVRL1,ADAM9,AFP,AKAP3,AKAP4,AMH,AMHR2,APELA,ARRB2,ATOH8,BAMBI,BMP10,BMP15,BMP2,BMP4,BMP5,BMP6,BMP7,BMP8A,BMP8B,BMPR1A,BMPR1B,BMPR2,BTBD11,CBL,CCL2,CDH5,CER1,CGN,CHRD,CHRDL1,CITED1,CITED2,CLDN5,COL1A2,COL3A1,CREB1,DDX5,DLX5,DSG4,DUSP15,DUSP22,EGR1,EID2,ENG,F11R,FAM83G,FERMT2,FKBP1A,FMOD,FNTA,FOS,FOXH1,FSHB,FSTL1,FURIN,FUT8,GCNT2,GDF1,GDF10,GDF11,GDF2,GDF3,GDF5,GDF6,GREM2,HFE2,HIPK2,HNF4A,HPGD,ID1,INHA,INHBA,INHBB,IRAK1,ITGB5,JUN,KLF10,LEF1,LEFTY1,LEFTY2,LNPEP,LRP4,LTBP4,MAGI2,MAP3K7,MAPK14,MAPK3,MEGF8,MSTN,MSX1,MSX2,MTMR4,NEDD8,NKX2-5,NLK,NOG,PARD3,PARD6A,PARP1,PDGFB,PML,PPM1L,PRKCZ,PTK2,PTPRK,PXN,RBM14,RGMA,RGMB,ROR2,RPS27A,RUNX2,RYR2,SCX,SKI,SKIL,SLC33A1,SMAD2,SMAD4,SMAD5,SMAD7,SMURF1,SMURF2,SOSTDC1,SRC,STUB1,SUB1,T,TAB1,TGFB1,TGFB1I1,TGFB2,TGFBR1,TGFBR2,TGFBRAP1,TGIF2,TMEM100,UBC,UBE2D1,UBE2D3,UBE2M,USP15,USP9X,USP9Y,VIM,WNT1,ZCCHC12,ZFYVE16,ZNF8,ZYX	TetrapodAncestor	111.013
GO.Biological.Process	GO:0071453	cellular.response.to.oxygen.levels	288	1.340939e-115	1.732091e-111	6.014205e-114	1.319725e+0	ACAA2,ADAM8,AIFM1,ANGPT4,ANKRD1,AQP1,AQP3,ATP6AP1,ATP6V0D1,ATP6V1G1,BACH1,BAD,BCL2,BMP7,BNIP3,BNIP3L,BRIP1,CA9,CARD16,CASR,CAV1,CBL,CCNA2,CCNB1,CFLAR,CITED2,CLCA1,COX4I2,CPEB1,CPEB2,CPEB4,CUL2,CYBB,DNM1L,DNMT3A,DNMT3B,E2F1,EDN1,EEF2K,EGLN1,EGLN2,EGLN3,EGR1,EIF4EBP1,ELOB,ELOC,ENDOG,EP300,EPAS1,EPO,ERO1A,FABP1,FAM162A,FAS,FMN2,FOXO1,GATA6,GNGT1,HIF1A,HIF1AN,HIF3A,HIGD1A,HIPK2,HMOX1,HYOU1,IRAK1,KCND2,KCNK2,KCNK3,KCNMB1,LIMD1,LMNA,LPAR1,MDM2,MDM4,MGARP,MTOR,MYC,MYOD1,NDNF,NDRG1,NKX3-1,NOP53,NOTCH1,NPEPPS,OPA1,OPRD1,P4HB,PCK1,PDK3,PGK1,PICK1,PINK1,PLK3,PMAIP1,PPARD,PPARG,PPARGC1A,PRKAA1,PRKCE,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTEN,PTGIS,PTN,RBPJ,RGCC,RPS27A,S100B,SFRP1,SIRT1,SIRT2,SIRT4,SLC29A1,SLC8A1,SLC8A3,SLC9A1,SRC,STC1,STC2,SUV39H2,TBL2,TERT,TIGAR,TMEM199,TP53,TRPC6,TWIST1,UBC,UBE2D1,UBE2D2,UBE2D3,UBQLN1,UCN3,VEGFA,ZFP36L1	TetrapodAncestor	110.761
GO.Biological.Process	GO:0048545	response.to.steroid.hormone	289	1.310709e-114	1.693043e-110	5.858280e-113	1.210050e+0	AANAT,ABCA2,ABCA3,ABCB4,ABCC2,ABHD2,ACSBG1,ADAM9,ADCYAP1,ADIPOQ,AGL,AGTR2,AGXT,AIF1,AIFM1,ALAD,ALDH3A1,ALPL,ANXA1,ANXA3,APOA2,AQP1,AR,AREG,ARG1,ARID1A,ATP1A1,ATP1A2,ATP2B1,AVPR1A,BAD,BCHE,BCL2,BGLAP,BMP4,BMP6,BMP7,BRCA1,CA2,CALCOCO1,CALCR,CALR,CARM1,CASP3,CASP9,CATSPER1,CATSPER2,CATSPER4,CATSPERB,CATSPERD,CAV1,CCL1,CCL2,CCND1,CCNE1,CD38,CDK7,CDKN1A,CDO1,CFLAR,CLDN1,CLDN4,CNGA3,COL1A1,CPN1,CPS1,CTGF,CTNNB1,CYBA,CYBB,DAXX,DDIT4,DDX17,DDX5,DDX54,DNAJA1,DNMT3B,DSG1,DSG2,DUSP1,EDN1,EGFR,EGLN2,EIF4E,EIF4EBP1,ENG,EPHX1,EPO,ERRFI1,ESR1,ESR2,ESRRA,ESRRB,ESRRG,FAS,FBXO32,FHL2,FIBIN,FKBP4,FOS,FOSB,FOSL1,FOXO1,GABRB1,GBA,GHRHR,GHSR,GLB1,GNRH1,GOT1,GPER1,GPR83,GRIP1,GSTP1,HEY1,HMGB1,HMGB2,HNF4A,HNF4G,HNMT,HNRNPU,HSD11B2,HTR1B,IFNB1,IGFBP2,IGFBP7,IL10,IL1RN,IL22,IL6,ISL1,JAK2,KAT5,KDM3A,KLF9,KRAS,LEF1,LOX,MAOB,MDK,MDM2,MED13,MED14,MED17,MED24,MED30,MED4,METTL21C,MGARP,MSTN,MYOD1,NCOA1,NCOA3,NCOA4,NCOA6,NEFL,NKX3-1,NOTCH1,NPAS4,NPC1,NR0B1,NR0B2,NR1D1,NR1D2,NR1H2,NR1H3,NR1H4,NR1I2,NR2C1,NR2C2,NR2E3,NR2F6,NR3C1,NR4A1,NR4A2,NR4A3,NR5A2,NRIP1,NTRK3,OR51E2,OXT,OXTR,PADI2,PAM,PAPPA,PAQR5,PAQR6,PAQR7,PAQR8,PARP1,PCK2,PCNA,PDCD7,PFKFB1,PGR,PGRMC2,PHB,PIAS1,PIAS2,PLPP1,PMEPA1,PPARA,PPARD,PPARG,PPARGC1A,PPARGC1B,PTAFR,PTGER2,PTN,PTPRU,RAMP2,RARA,RARB,RARG,RB1,RBBP7,RBFOX2,RBM14,RELA,REST,RNF14,RNF4,RORB,RORC,RWDD1,RXRA,RXRB,RXRG,S100B,SAFB,SCGB1A1,SLIT2,SLIT3,SMYD3,SOX10,SOX30,SPP1,SRC,SRD5A1,SRD5A2,SREBF1,SST,SSTR2,SSTR3,SSTR4,SSTR5,STAR,STC1,TADA3,TAT,TGFB1,TGFB1I1,TGFB2,TGFBR2,TH,THBS1,THRA,THRAP3,THRB,TLR2,TNF,TPH2,TRIM63,TRIP4,TSPO,TXNIP,TYMS,UBE2L3,UBE3A,UBR5,UCN,UCN3,UCP3,UGT1A1,USP8,VDR,WNT7B,YAP1,YWHAH,ZFP36,ZFP36L1,ZFP36L2	TetrapodAncestor	109.771
GO.Biological.Process	GO:0050678	regulation.of.epithelial.cell.proliferation	290	1.329747e-114	1.717634e-110	5.922877e-113	1.201377e+0	A4GNT,ACVRL1,AGGF1,APOE,APOH,AR,ARG1,ATOH8,ATP5A1,ATPIF1,B4GALT1,BAD,BAX,BCL11B,BMP2,BMP4,BMP5,BMP6,BMPR1A,BMPR2,CASK,CAV1,CAV2,CCL11,CCL2,CCL5,CCND1,CCR3,CD109,CDC42,CDC73,CDH13,CDH3,CDK6,CDKN1B,CDKN1C,CDKN2B,CFLAR,CPB2,CTNNB1,CYBA,DAB2IP,DEAF1,DLG1,DLL4,DLX5,DUSP10,EDNRB,EFNB2,EGFL7,EGFR,EGR3,EPGN,ERBB2,EREG,ERRFI1,ESRP2,EYA1,F3,FBXW7,FGF1,FGF10,FGF2,FGF7,FGF9,FGFR2,FLT4,FMC1,FOXE3,FOXP2,FRS2,FZD7,GATA3,GDF2,GDF5,GHSR,GJA1,GLUL,GPC3,HAS2,HES1,HES5,HIF1A,HMGB2,HMGN1,HPN,HRAS,HTR2B,HTRA1,ID1,IFNG,IFT172,IFT52,IFT57,IFT74,IGF1,IHH,IL10,IL26,IL6,INTU,IQGAP3,ISL1,JAML,JCAD,JUN,KDF1,KDM5B,KLF9,KRIT1,LACRT,LAMB1,LEP,LIMS2,LRG1,MARVELD3,MCC,MEF2C,MEN1,MMP12,MTOR,MTSS1,MYC,MYDGF,NF1,NFIB,NGFR,NKX3-1,NLRC3,NME1,NME2,NOG,NOTCH1,NR1D1,NR4A1,NR4A3,NRP1,NRP2,OSR1,OVOL2,PAX2,PBLD,PDCD10,PDCD6,PDCL3,PDGFB,PEX2,PGR,PPARD,PPP1R16B,PRKCA,PRKD1,PRKD2,PROX1,PTCH1,PTEN,PTN,PTPRK,PTPRM,PYGO2,RB1,REG3A,REG3G,RGCC,RGN,RICTOR,ROBO1,RPTOR,RREB1,RTN4,SCG2,SCN5A,SEMA5A,SERPINB5,SFN,SFRP1,SFRP2,SIRT1,SIRT6,SLURP1,SMO,SNAI2,SOX11,SOX2,SOX9,SRSF6,STAT1,STRAP,STXBP4,SULF2,SYNJ2BP,TACSTD2,TBX1,TEK,TGFB1,TGFB2,TGFBR1,TGM1,THBS1,THBS4,TINF2,TNF,TNFAIP3,TNFSF12,TNMD,TP63,TWIST1,VASH1,VASH2,VDR,VEGFA,VEGFB,VEGFC,VEGFD,VHLL,WDR77,WFDC1,WNT10B,WNT3A,WNT5A,WNT7A,XBP1,XDH,ZFP36,ZFP36L1,ZNF580,ZNF703	TetrapodAncestor	109.765
GO.Biological.Process	GO:0002064	epithelial.cell.development	291	1.578978e-114	2.039566e-110	7.008817e-113	1.272234e+0	ACTA2,AFDN,AR,ARHGEF26,ARID4A,B4GALT1,BCL11B,BFSP1,BFSP2,BMP15,BMP4,BMP5,BMP6,C1GALT1,CCM2,CDC42,CDK6,CDKN1A,CLDN1,CLDN3,CLIC5,COL18A1,CTNNB1,DACT2,DLL1,DMRT1,DNASE1L2,E2F4,ENG,EPB41L5,EPHA2,ESR1,EXPH5,EZR,F11R,F2RL1,FEM1B,FGFR1,FLNB,FNDC3A,FOSL2,FOXA1,FOXC2,FOXJ1,FRMD6,FRS2,GPAT4,GPR4,GRHL2,GSTM3,HAPLN2,HEG1,HIF1A,HRH2,HSD17B4,HYDIN,ID1,IFT74,IHH,INSM1,IQGAP1,JAG1,KDF1,KLF5,KRT2,LHFPL5,LRTOMT,MAGI2,MARVELD2,MET,MSN,MYADM,MYO1E,NKX3-2,NKX6-1,NOTCH1,NOTCH4,NPHS1,NPHS2,NTRK1,NUP210L,ONECUT1,PAFAH1B1,PALLD,PDE2A,PDE4D,PDGFB,PDPK1,PDZD7,PGR,PODXL,POF1B,PPP1R16B,PRDM1,PROX1,PTPRS,RAB13,RAB25,RAP1A,RAP1B,RAP2C,RAPGEF1,RAPGEF2,RAPGEF3,RARA,RARB,RARG,RDX,RFX3,RILPL1,ROS1,SCRIB,SEC24B,SFN,SHROOM3,SIDT2,SIPA1L3,SLC4A5,SLC4A7,SLC9A3R1,SLC9A4,SLITRK6,SMO,SOD1,SOX18,SOX8,SOX9,ST14,STC1,STRC,TBC1D20,TFCP2L1,TIGAR,TJP1,TJP2,TMC1,TMEM79,TMOD1,TNMD,TP63,TYMS,VEZF1,VIM,VSIG1,WNT5A,WNT7A,WNT7B,XBP1,YIPF6	TetrapodAncestor	109.69
GO.Biological.Process	GO:0090068	positive.regulation.of.cell.cycle.process	292	4.983447e-114	6.437118e-110	2.204493e-112	1.271089e+0	AIF1,ANAPC11,ANKRD17,ANXA1,APEX1,APP,ATM,AURKA,AURKB,AURKC,BAX,BECN1,BRCA1,BRD4,BTC,BTG2,CARM1,CASP2,CCL2,CCNB1,CCND1,CCND2,CD28,CDC25A,CDC25B,CDC25C,CDC42,CDC45,CDC6,CDC73,CDCA5,CDK1,CDK10,CDK2,CDK4,CDK5R1,CDKN1A,CDKN1B,CENPJ,CEP120,CHEK2,CIT,CNOT1,CNOT10,CNOT11,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT8,CRADD,CRLF3,CTGF,CUL3,CUL4A,CXCR5,CYP1A1,DAB2IP,DAZL,DBF4B,DDRGK1,DDX11,DDX3X,DLGAP5,DMRT1,DRD2,DRD3,DYNC1LI1,E2F1,E2F4,E2F7,E2F8,ECT2,EDN1,EDN3,EGF,EP300,EPGN,EREG,ESPL1,FAM83D,FEN1,FGFR1,FOXO4,GADD45A,GATA6,GEN1,GIPC1,GML,GTSE1,H2AFY,HMGA2,HNRNPU,ID2,IGF1,IGF2,IL1A,IL1B,INO80,INS,INSM1,KCNA5,KIF20B,KIF3B,LRP5,LSM11,MAD2L1,MAP10,MDM2,MDM4,MECP2,MED25,MEPCE,MSX1,MSX2,MTA3,MTBP,MUC1,MYBBP1A,MYOG,NDC80,NEUROG1,NPM1,NPM2,NSMCE2,NUDT16,NUP62,NUSAP1,OPN1LW,OR1A2,OR2A4,PAF1,PAGR1,PBX1,PCBP4,PCID2,PCNA,PDGFB,PDGFRB,PHIP,PHOX2B,PIDD1,PIWIL2,PKD2,PLAGL1,PLCB1,PLK2,PLK3,PLK4,PML,POC1A,POU4F1,PPP2R5B,PRDM9,PRKACA,PRKCE,PRMT1,RAB11FIP4,RACGAP1,RAD21,RAD51B,RAD51C,RANBP2,RANBP3,RANBP3L,RB1,RCC2,RDX,RGCC,RGPD4,RHNO1,ROCK2,RPL23,RPS27A,RPTOR,RXFP3,SFN,SFPQ,SH2B1,SIRT2,SLF1,SLF2,SMC5,SOX15,SOX4,SPAST,SSTR5,STXBP4,SVIL,TAS1R2,TAS2R13,TERT,TFDP2,TGFB1,TMOD3,TNKS1BP1,TOPAZ1,TP53,TP73,TPR,TRIAP1,UBC,UBE2C,UBE2E2,UHRF2,VPS4B,WIZ,WNT10B,WNT4,WNT5A,ZBTB17,ZNF16,ZNF385A	TetrapodAncestor	109.191
GO.Biological.Process	GO:0048332	mesoderm.morphogenesis	293	5.526169e-114	7.138152e-110	2.436230e-112	1.414863e+0	BMP4,BMP7,BMPR1A,BMPR2,CHRD,CRB2,DKK1,EOMES,EPB41L5,EPHA2,EXOC4,EXT2,EYA1,EYA2,FGFR2,FOXC1,FOXC2,FOXF1,HAND1,HMGA2,INHBA,ITGA2,ITGA3,ITGA8,ITGB1,ITGB4,KDM6A,KDM6B,KLF4,LEF1,MESP1,MESP2,MSGN1,NF2,NOG,NR4A3,PAX2,POFUT2,PRKACA,PRKAR1A,SCX,SETD2,SIX2,SMAD2,SNAI1,SRF,T,TAL1,TBX20,TBX3,TBX6,TLX2,TXNRD1,WLS,WNT11,WNT3,WNT3A,WNT5A	TetrapodAncestor	109.146
GO.Biological.Process	GO:0030336	negative.regulation.of.cell.migration	294	1.052820e-113	1.359928e-109	4.625604e-112	1.230370e+0	ABHD2,ABHD6,ABR,ACVRL1,ADA,ADAM15,ADAMTS9,ADARB1,ADGRB1,ADGRG1,ADIPOQ,ADIPOR1,ADORA1,ADORA3,AGTR2,AIF1,ALOX15B,ANGPT2,ANGPT4,APEX1,APOD,APOE,APOH,ARAP3,ARHGAP4,ARHGDIB,ARID2,ARPIN,BCL2,BCR,BMP10,BMP5,BMPR1A,BRAF,BST2,C16orf45,C5,C5orf30,CALR,CCL2,CCL21,CCL28,CD300A,CERS2,CHRD,CITED2,CLASP1,CLASP2,COL3A1,CORO1B,CSNK2B,CX3CL1,CX3CR1,CXCL13,CYGB,CYP19A1,CYP1B1,DAB2IP,DACH1,DCN,DDT,DLC1,DLG5,DLL4,DPEP1,DPYSL3,DRD2,DUSP10,ENG,EPHA1,ERBB4,EVL,FAM60A,FGF2,FLCN,FUZ,GDF2,GNRH1,GPR18,GREM1,GSTP1,HDAC5,HMGB1,HMOX1,HRG,IDH2,IFITM1,IGFBP5,IL24,IL33,IL4,KANK1,KLF4,KLRK1,KRIT1,KRT16,LDLRAD4,LRCH1,LRP1,MAGI2,MARVELD3,MCC,MCTP1,MEOX2,MIA3,MIF,MIIP,MMP28,MMRN2,MYOCD,NAV3,NBL1,NDRG4,NF1,NF2,NISCH,NOG,NOTCH1,NOV,NRG1,NRG3,PADI2,PBLD,PDCD10,PFN2,PHLDB2,PKP2,PLCB1,PODN,PPARD,PPARG,PPARGC1A,PTEN,PTGER4,PTN,PTPN23,PTPRG,PTPRJ,PTPRK,PTPRM,PTPRR,PTPRU,RAP2A,RAP2B,RAP2C,RECK,RGCC,RIPOR2,RNF20,RNF41,ROBO1,RRAS,SCAI,SEMA3A,SEMA6D,SFRP1,SFRP2,SLC9A3R1,SLIT2,SLURP1,SMAD7,SP100,SPRED1,SRF,SRGAP1,SRGAP2,SRGAP2B,SRGAP2C,SRGAP3,STAP1,STARD13,STC1,STK24,STK26,STRAP,SYNJ2BP,TACSTD2,TBX5,TGFB1,THBS1,THY1,TIE1,TIMP1,TMEFF2,TMIGD3,TP53INP1,TRIB1,VASH1,VCL,WNT11,WNT4,ZMYND8	TetrapodAncestor	108.866
GO.Biological.Process	GO:0072132	mesenchyme.morphogenesis	295	1.578630e-113	2.039116e-109	6.912259e-112	1.461441e+0	ACTA2,ACTG2,ACVRL1,BMP2,BMP5,BMP7,BMPR1A,DCHS1,ENG,EXOC4,FOXC1,FOXC2,FOXF1,HEY1,HEYL,ISL1,LEF1,MDM2,MSX1,MSX2,NOG,NOTCH1,OSR1,RBPJ,SMAD2,SMAD4,SNAI1,SNAI2,SOX9,TBX2,TBX20,TGFB2,TGFBR2,TMEM100,TWIST1,WNT11,WNT3A,WNT5A	TetrapodAncestor	108.691
GO.Biological.Process	GO:2000146	negative.regulation.of.cell.motility	296	2.592563e-113	3.348814e-109	1.131356e-111	1.223713e+0	ABHD2,ABHD6,ABR,ACVRL1,ADA,ADAM15,ADAMTS9,ADARB1,ADGRB1,ADGRG1,ADIPOQ,ADIPOR1,ADORA1,ADORA3,AGTR2,AIF1,ALOX15B,ANGPT2,ANGPT4,AP1AR,APEX1,APOD,APOE,APOH,ARAP3,ARHGAP4,ARHGDIB,ARID2,ARPIN,BCL2,BCR,BMP10,BMP5,BMPR1A,BRAF,BST2,C16orf45,C5,C5orf30,CALR,CCDC125,CCL2,CCL21,CCL28,CD300A,CERS2,CHRD,CITED2,CLASP1,CLASP2,COL3A1,CORO1B,CRK,CSNK2B,CTNNA1,CX3CL1,CX3CR1,CXCL13,CYGB,CYP19A1,CYP1B1,DAB2IP,DACH1,DCN,DDT,DLC1,DLG5,DLL4,DPEP1,DPYSL3,DRD2,DUSP10,ENG,EPHA1,EPPIN,EPPIN-WFDC6,ERBB4,EVL,FAM60A,FBLN1,FGF2,FLCN,FRMD5,FUZ,GATA3,GDF2,GNRH1,GPR18,GREM1,GSTP1,HDAC5,HMGB1,HMOX1,HRG,IDH2,IFITM1,IGFBP5,IL24,IL33,IL4,KANK1,KLF4,KLRK1,KRIT1,KRT16,LDLRAD4,LRCH1,LRP1,MAGI2,MARVELD3,MCC,MCTP1,MEOX2,MIA3,MIF,MIIP,MMP28,MMRN2,MYOCD,NAV3,NBL1,NDRG4,NF1,NF2,NISCH,NOG,NOTCH1,NOV,NRG1,NRG3,PADI2,PBLD,PDCD10,PFN2,PHLDB2,PIN1,PKP2,PLCB1,PODN,PPARD,PPARG,PPARGC1A,PTEN,PTGER4,PTN,PTPN23,PTPRG,PTPRJ,PTPRK,PTPRM,PTPRR,PTPRU,RAP2A,RAP2B,RAP2C,RECK,RGCC,RGN,RIPOR2,RNF20,RNF41,ROBO1,RRAS,SCAI,SEMA3A,SEMA6D,SEMG1,SEMG2,SFRP1,SFRP2,SLC9A3R1,SLIT2,SLURP1,SMAD7,SP100,SPOCK3,SPRED1,SRF,SRGAP1,SRGAP2,SRGAP2B,SRGAP2C,SRGAP3,STAP1,STARD13,STC1,STK24,STK26,STRAP,SYNJ2BP,TACSTD2,TBX5,TGFB1,THBS1,THY1,TIE1,TIMP1,TMEFF2,TMIGD3,TP53INP1,TRIB1,VASH1,VCL,WNT11,WNT4,ZMYND8	TetrapodAncestor	108.475
GO.Biological.Process	GO:0097190	apoptotic.signaling.pathway	297	8.406179e-113	1.085826e-108	3.655980e-111	1.255855e+0	ABL1,ACVR1B,ADORA1,AEN,AIFM1,ANXA6,APAF1,APPL1,ARL6IP5,ATF4,ATM,ATP2A1,BAD,BAG6,BAK1,BAX,BCL2,BCL2A1,BCL2L1,BCL2L10,BCL2L11,BCL2L2,BCL2L2-PABPN1,BCL3,BID,BLOC1S2,BNIP3,BNIP3L,BRCA1,BRSK2,BTK,CASP10,CASP2,CASP3,CASP4,CASP8,CASP9,CAV1,CCK,CD14,CD24,CD27,CD28,CD38,CD3E,CD40,CD5,CD70,CDIP1,CDKN1A,CEBPB,CHAC1,CHEK2,CIB1,CIDEB,CLU,CRADD,CRIP1,CUL1,CUL2,CUL3,CUL4A,CUL5,CYCS,CYP1B1,DAB2IP,DAP,DAP3,DAPK1,DAPK3,DAXX,DCC,DDIT4,DDX3X,DDX47,DDX5,DEDD,DEDD2,DIDO1,DNAJC10,DNM1L,DPF2,DYRK2,E2F1,E2F2,EDA2R,EP300,EPHA2,ERCC6,ERN1,ERN2,ERO1A,EYA2,FADD,FAS,FASLG,FASTK,FGFR3,FHIT,FIS1,FZD9,G0S2,GGCT,GSK3A,GSKIP,HIC1,HINT1,HIP1,HIPK1,HIPK2,HMOX1,HRAS,HTRA2,IFI27,IFI6,IFNG,IKBKE,IL12A,IL1A,IL1B,IL2,IL33,IL4,IL6R,INHBA,ITGAV,ITPR1,JAK2,JMY,JUN,KIAA0141,KITLG,KRCC1,LCN2,LGALS12,LY96,MAEL,MAP3K5,MELK,METTL21C,MFF,MKNK2,MLH1,MLLT11,MSH2,MSH6,MYBBP1A,NBN,NF1,NFATC4,NGF,NGFR,NOL3,NUPR1,P2RX4,P2RX7,PARP2,PAWR,PDCD10,PDCD6,PDK2,PDPK1,PERP,PGAP2,PIK3R1,PMAIP1,PML,POLB,POU4F1,PPARD,PPM1F,PPP1R13B,PPP1R15A,PRKCA,PRKCD,PRKDC,PRODH,PTGIS,PTH,PYCARD,RAF1,RELT,RIPK1,RIPK3,RNF41,RPS27L,SART1,SELENOK,SFN,SGPL1,SGPP1,SIRT1,SNW1,SOD2,SPN,SST,SSTR3,STK24,TFPT,TGFB1,TGFB2,TICAM1,TICAM2,TIMM50,TLR3,TLR4,TM2D1,TMBIM6,TMEM109,TMEM117,TNF,TNFRSF10A,TNFRSF10B,TNFRSF10C,TNFRSF10D,TNFRSF11A,TNFRSF11B,TNFRSF12A,TNFRSF14,TNFRSF18,TNFRSF1A,TNFRSF1B,TNFRSF21,TNFRSF25,TNFRSF4,TNFRSF8,TNFRSF9,TNFSF12,TOPORS,TP53,TP53BP2,TP63,TP73,TRADD,TRAF2,TRIB3,UACA,USP28,WWOX,XBP1,XPA,ZMAT3,ZMAT4,ZNF346,ZNF385B,ZNF385D,ZNF622	TetrapodAncestor	107.964
GO.Biological.Process	GO:0034599	cellular.response.to.oxidative.stress	298	9.516852e-113	1.229292e-108	4.125140e-111	1.285041e+0	ABL1,ADNP2,ADPRHL2,AIF1,AIFM1,AKR1B1,ALDH3B1,ANKRD2,ANKZF1,ANXA1,APEX1,APOA4,AQP1,ARG1,ARL6IP5,ARNTL,ATF4,ATP13A2,AXL,BCL2,BECN1,BNIP3,BRF2,BTK,CAMKK2,CAT,CBX8,CCNA2,CCS,CD36,CDK1,CDK2,CFLAR,CHD6,CHUK,CPEB2,CRK,CRYGD,CYBA,CYBB,CYCS,CYP1B1,DAPK1,DHRS2,DNM2,DPEP1,ECT2,EGFR,ENDOG,ENSG00000256632,EPAS1,ERCC6L2,ERO1A,ETS1,ETV5,EZH2,FABP1,FANCC,FER,FOS,FOXO1,FXN,G6PD,GLRX2,GPX2,GPX3,GPX7,GPX8,GSKIP,GSR,GSTP1,GUCY1B3,HDAC2,HIF1A,HMOX1,HNRNPD,HSF1,HTRA2,IL18BP,IL18RAP,IL6,JAK2,JUN,KCNC2,KDM6B,KLF2,KLF4,LCN2,LONP1,LRRK2,MAP1LC3A,MAP3K5,MAPK1,MAPK3,MAPK8,MAPK9,MDM2,MELK,MGST1,MMP3,MMP9,MPO,MPV17,MYB,NCF1,NCF2,NCF4,NET1,NME2,NME8,NOS3,NOX4,NOX5,NQO1,NR4A2,NUDT2,OXR1,P4HB,PARK7,PARP1,PAX2,PCGF2,PCNA,PDCD10,PDGFD,PDK2,PENK,PINK1,PKD2,PLEKHA1,PML,PNPT1,PPARGC1A,PPARGC1B,PPIF,PPP5C,PRDX1,PRDX2,PRDX3,PRDX5,PRKAA1,PRKCD,PRKD1,PRKRA,PRODH,PRR5L,PTPRK,PXN,PYCR1,PYCR2,PYROXD1,RAD52,RBM11,RELA,ROMO1,RPS3,RWDD1,SESN2,SETX,SIRT1,SIRT2,SLC25A24,SNCA,SOD1,SOD2,SOD3,SRC,SRXN1,STAT6,STAU1,STK24,TMEM161A,TNFAIP3,TP53,TP53INP1,TRAF2,TRPC6,TRPM2,TXN,TXN2,TXNDC2,TXNDC8,TXNL1,TXNRD1,UCP1,VKORC1L1,VRK2,WNT16,ZC3H12A,ZNF277,ZNF580,ZNF622	TetrapodAncestor	107.91
GO.Biological.Process	GO:0044265	cellular.macromolecule.catabolic.process	299	9.644329e-113	1.245758e-108	4.166415e-111	1.162091e+0	ABTB1,ABTB2,ADAMTS12,ADAMTS7,ADAMTS9,ADRM1,AGO1,AGO3,AGO4,AMER1,AMFR,ANAPC1,ANAPC11,ANAPC16,ANAPC2,ANAPC4,ANAPC5,ANKIB1,ANKZF1,AP2A1,AP2A2,AP2B1,AP2M1,AP2S1,APC,ARIH1,ARNTL,ARRB1,ARRB2,ATE1,ATM,ATXN3,AUP1,AURKA,AURKB,BAG6,BAP1,BFAR,BIRC2,BNIP3,BNIP3L,BTBD11,BTBD2,BTBD3,BTBD6,BTBD9,BTRC,C17orf97,C2orf40,CACUL1,CAPN2,CASC3,CASP3,CASP8,CBL,CBLC,CCDC47,CCIN,CCNB1,CCNF,CD2AP,CDC16,CDC20,CDC23,CDC26,CDC27,CDC34,CDK1,CECR2,CHEK2,CHFR,CHMP4B,CHMP4C,CLN6,CLPP,CLPX,CLTA,CLTC,CNOT1,CNOT10,CNOT11,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT8,COPS3,CPA2,CPVL,CRBN,CSDE1,CSNK1A1,CTIF,CTNNB1,CTSA,CTSB,CTSC,CTSH,CTSL,CTSO,CTSW,CTSZ,CUL1,CUL2,CUL3,CUL4A,CUL5,CUL7,CUL9,DAB2IP,DCP2,DCPS,DCST1,DDB1,DDX5,DEDD2,DENND3,DERL1,DERL2,DERL3,DFFA,DFFB,DIS3L2,DNA2,DNAJC10,DNASE1,DNASE1L1,DNASE1L2,DNASE1L3,DNASE2,DROSHA,DTX3L,DXO,DZIP3,EDC3,EDC4,EDEM1,EDEM2,EDEM3,EIF3E,EIF4A1,EIF4A2,EIF4A3,EIF4E,ELOC,ENDOG,ENSG00000258677,ENSG00000261884,ENSG00000265303,ENSG00000282246,ERCC8,ERLIN1,ERLIN2,ERN1,ERN2,ETF1,EXOSC1,EXOSC10,EXOSC2,EXOSC3,EXOSC4,EXOSC5,EXOSC6,EXOSC7,EXOSC9,FAF1,FAF2,FBXL12,FBXL15,FBXL19,FBXL2,FBXL22,FBXL3,FBXL5,FBXL7,FBXO10,FBXO15,FBXO18,FBXO2,FBXO21,FBXO22,FBXO31,FBXO39,FBXO4,FBXO44,FBXO45,FBXO6,FBXO7,FBXO8,FBXW11,FBXW5,FBXW7,FEN1,FOXRED2,FZR1,GID4,GPC1,GSK3A,GSPT1,GTSE1,GZMA,H1F0,HACE1,HBS1L,HECTD3,HECW1,HECW2,HERC2,HERPUD1,HMGB1,HMGB2,HNRNPD,HPSE,HSP90B1,HSPA5,HTRA2,IDE,ISG15,ISG20,ITCH,JKAMP,KAT5,KBTBD4,KBTBD8,KCTD13,KCTD17,KCTD2,KCTD21,KCTD5,KCTD6,KEAP1,KHSRP,KIAA0368,KLHL15,KLHL2,KLHL20,KLHL25,KLHL29,KLHL3,KLHL42,KLHL8,KPNA1,KPNB1,LGMN,LIN28A,LIN28B,LNX1,LONP1,LONP2,LSM1,LSM3,LSM5,LSM7,MAD2L1,MAEA,MAGEC2,MAGOH,MAGOHB,MAN1B1,MARCH6,MDM2,METTL14,METTL3,MLH1,MRTO4,MTA1,MTPAP,MUS81,MVB12A,MYLIP,NANOS2,NBAS,NCBP1,NCBP2,NEDD4L,NEDD8,NEU4,NHLRC1,NOCT,NR1D1,NSFL1C,NTAN1,NUB1,NUDT16,OMA1,OS9,OTUD7A,OTUD7B,PABPC4,PAIP1,PAN2,PAN3,PAPD4,PARN,PATL1,PCBP2,PCID2,PCNP,PCYOX1,PCYOX1L,PDCD6IP,PDE12,PELO,PINK1,PLAA,PLG,PLK1,PMAIP1,PML,PNLDC1,PNPT1,PNRC1,PNRC2,POLR2D,POLR2G,POMT1,POMT2,PPP1R8,PPP2CB,PPP2R2A,PPP2R5C,PRKN,PRPF18,PRPF19,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTPN23,PTTG1,PYM1,RAB12,RAB7A,RAD23A,RAD23B,RANBP2,RANBP3,RANBP3L,RBCK1,RBM8A,RC3H1,RCHY1,RFFL,RFWD2,RGPD4,RIPK1,RLIM,RMND5A,RMND5B,RNASEH1,RNASEH2A,RNASEH2B,RNASEH2C,RNASET2,RNF103,RNF11,RNF115,RNF121,RNF122,RNF125,RNF126,RNF128,RNF139,RNF14,RNF144A,RNF144B,RNF145,RNF146,RNF168,RNF175,RNF181,RNF185,RNF19B,RNF20,RNF213,RNF216,RNF217,RNF222,RNF24,RNF34,RNF38,RNF4,RNF40,RNF41,RNF43,RNF44,RNF5,RNF6,RNF7,RNF8,RNH1,RNPS1,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL23,RPL23A,RPL24,RPL27,RPL28,RPL29,RPL3,RPL30,RPL31,RPL34,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL5,RPL6,RPL7,RPL7A,RPL8,RPLP0,RPLP2,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS17,RPS18,RPS20,RPS21,RPS23,RPS24,RPS25,RPS26,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS4X,RPS5,RPS6,RPS7,RPS8,RPSA,SAMD4A,SAMD4B,SCPEP1,SDF2L1,SEC61B,SEL1L,SETMAR,SGSH,SGTA,SHARPIN,SIAH1,SIAH2,SIAH3,SIDT2,SIRT1,SIRT2,SKIV2L2,SKP2,SLFN14,SMG1,SMG5,SMG6,SMG7,SMG8,SMURF1,SMURF2,SND1,SNF8,SOCS6,SPATA18,SPO11,SPOP,SPOPL,SQSTM1,STK31,STT3B,STUB1,SYVN1,TAF1,TATDN1,TBL1X,TBL1XR1,TCIRG1,TGFB1I1,THRAP3,TMEM129,TMEM199,TMEM67,TMUB1,TNFAIP1,TNFAIP3,TNKS1BP1,TOLLIP,TOM1L1,TOPORS,TOR1A,TP53,TP53INP2,TRIM13,TRIM25,TRIM32,TRIM58,TRIM72,TRIM9,TRIP12,TRPC4AP,TSG101,TTC3,TTC37,UBA1,UBA6,UBA7,UBAP1,UBAP1L,UBC,UBE2A,UBE2C,UBE2D1,UBE2D2,UBE2D3,UBE2E1,UBE2G2,UBE2H,UBE2I,UBE2J1,UBE2J2,UBE2L3,UBE2L5P,UBE2L6,UBE2N,UBE2R2,UBE2S,UBE2W,UBE3A,UBE4A,UBQLN1,UBR1,UBR2,UBR4,UBR5,UBXN1,UBXN11,UBXN2B,UBXN4,UBXN8,UCHL1,UCHL5,UFD1,UGGT1,UHRF1,UPF1,UPF2,UPF3A,USP1,USP10,USP11,USP13,USP14,USP15,USP16,USP17L3,USP17L30,USP18,USP2,USP20,USP21,USP22,USP24,USP25,USP26,USP28,USP3,USP31,USP32,USP35,USP36,USP37,USP38,USP40,USP41,USP42,USP46,USP47,USP48,USP49,USP50,USP7,USP8,USP9X,USP9Y,VCP,VHLL,VLDLR,VPS25,VPS28,VPS36,VPS4A,VPS4B,WDR61,WDR81,WFS1,WNT1,WWP1,WWP2,WWTR1,XBP1,XRN1,YME1L1,YOD1,ZC3H12A,ZCCHC11,ZCCHC6,ZFP36,ZFP36L1,ZFP36L2,ZHX2,ZMPSTE24,ZNRF1,ZNRF2,ZNRF3,ZNRF4,ZPR1	TetrapodAncestor	107.905
GO.Biological.Process	GO:0051051	negative.regulation.of.transport	300	5.750466e-112	7.427877e-108	2.475959e-110	1.180902e+0	ABAT,ABCC8,ABR,ACAA2,ADA,ADCYAP1,ADIPOQ,ADORA1,ADRA2A,ADRA2B,ADRA2C,AGTR2,AKT2,ANGPT1,ANK3,ANKRD27,ANO9,ANXA1,ANXA4,APC2,APOA1,APOA2,APOC1,APOC3,APOD,ARF6,ARG2,ARHGAP1,ARL6IP5,ASIC1,ATF4,ATG3,ATG5,ATP1A2,ATXN2,AVPR2,AXIN2,BAG4,BANK1,BARD1,BCL2,BCR,BEST3,BMP7,BMP8A,BRAF,BST2,C1QTNF3,CAB39,CABP1,CALM1,CALM2,CALM3,CAMK2D,CARD16,CARD17,CARD18,CARTPT,CASQ2,CAV1,CAV3,CCDC22,CCR2,CD300A,CD300LF,CD34,CD36,CD74,CDK5,CHGA,CHP1,CIDEA,CNR1,COMMD1,CORO1A,CRBN,CRHBP,CRHR1,CRY1,CRYAA,CRYAB,CSK,CYFIP1,DAB2IP,DACT3,DCANP1,DERL2,DERL3,DLG4,DMTN,DPH3,DRD2,DRD3,DRD4,DYRK2,EDN1,EGF,ENPP1,EPHA3,EPHB2,EPO,EPPIN,EPPIN-WFDC6,ERP29,EZR,F2R,F2RL1,FAF1,FAM3D,FAM89B,FBXW11,FERMT1,FFAR4,FGF12,FGF23,FKBP1B,FMR1,FN1,FOXF1,FOXP3,FZD1,FZD9,G3BP2,GAS6,GDI1,GHSR,GNAO1,GNB5,GOPC,GPM6B,GPR35,GRB10,GRM7,GSK3A,GSTM2,HAMP,HMGB1,HMGCR,HMOX1,HRC,HRH3,HTR1B,HTR2A,IDH2,IFNA2,IL10,IL13RA2,IL1B,IL1R2,IL1RAPL1,IL33,IL36RN,IL6,INHA,INHBA,INHBB,INPP5K,INS,IRS1,IRS2,ISX,ITGAV,JAGN1,KALRN,KCNA5,KCNAB1,KCNB1,KCNE1,KCNE2,KCNE3,KCNE5,KCNH2,KCNJ11,KCNRG,KEAP1,KEL,LEP,LGALS3,LGALS9,LGR4,LIF,LILRB2,LITAF,LMBRD1,LRPAP1,LRRC32,LRRK2,LRRTM1,LRRTM2,LRSAM1,LYPLA1,MAOB,MAP1B,MAP4K4,MCTP1,MDFI,MMP9,MPV17L,MTMR2,MTOR,MZB1,NDFIP1,NDFIP2,NDUFAF2,NECAB2,NEDD4L,NEUROG1,NF1,NFKB1,NLRP7,NOS1,NOS3,NOTCH1,NOV,NPFF,NPVF,NPY2R,NPY5R,NR1H2,NR1H3,NR1H4,NRG1,NTSR1,NUP153,OAZ1,OAZ2,OAZ3,OPRK1,OPRL1,OPRM1,OR56A1,OR56A4,OR5T3,OS9,OSM,OSR1,OSTN,OXT,OXTR,P2RY1,PACSIN2,PACSIN3,PARK7,PARP10,PBLD,PDE2A,PDE8B,PEA15,PFKL,PICALM,PID1,PIM3,PKD1,PKD2,PKDCC,PKIA,PKIG,PLA2G10,PLN,PML,PNKD,PPIF,PPP3CA,PRKAA1,PRKCB,PRKCE,PRKD1,PRKG2,PRKN,PROM2,PSMD10,PSMD9,PTEN,PTGER3,PTGER4,PTK2B,PTPN11,PTPN22,PYDC2,RAB11FIP1,RAB11FIP5,RAB23,RAB33B,RAB7A,RAC1,RAP1A,RAP1B,REM1,REM2,REST,RGCC,RHBDF1,RHBDF2,RRAD,RSAD2,RSC1A1,RUBCN,SCAMP5,SCT,SDCBP,SEMG1,SERGEF,SERPINE2,SESTD1,SFRP1,SFRP4,SFRP5,SIAH3,SIRT4,SIRT6,SLC25A5,SLC26A5,SLC30A1,SLC35F6,SLC9A3R1,SLN,SNAI2,SNCA,SNX12,SOX4,SP100,SPINK1,SPX,SRCIN1,SREBF1,SREBF2,SRI,SSC5D,STC1,STX1B,STXBP5L,STXBP6,SUFU,SUMO1,SVIP,SYT11,SYT4,SYTL4,TBC1D10C,TBC1D4,TGFB1,THBS1,THRA,TIFAB,TLR2,TLR6,TLR9,TMBIM6,TMEM14A,TNF,TNFRSF21,TNFRSF9,TONSL,TPR,TRAT1,TRDN,TRIM9,TWIST1,TXN,UBAC2,UBE2G2,UBE2J1,UBQLN1,UCN,UCP2,UNC119,UTS2,UTS2R,VAMP3,VAMP8,VPS35,VPS4B,VSNL1,WNK1,WNK3,WNK4,WWP2,WWTR1,YOD1,YRDC,YWHAE,ZC3H12A	TetrapodAncestor	107.129
GO.Biological.Process	GO:0001701	in.utero.embryonic.development	301	9.748829e-112	1.259256e-107	4.183576e-110	1.215506e+0	ACVR1B,ACVRL1,ADA,ADAR,ADD1,ALKBH1,ALS2,AMOT,ANGPT1,APBA1,APBA2,APBA3,APOB,AR,ARNT2,ASCL2,B9D1,BCL2L1,BCL2L11,BIRC6,BMP2,BMP5,BMP7,BMPR1A,BYSL,C2CD3,C5,C6,CAPN2,CASP8,CCM2,CCNB1,CCNB1IP1,CDKN1C,CEBPA,CEBPB,CHD7,CHD8,CITED1,CNOT2,CNOT3,COPS3,CTNNB1,CUL3,CUL4A,CYR61,DAD1,DNAJB6,DUSP3,E2F7,E2F8,EDN1,EGFR,EGLN1,EIF2S2,EIF4E2,ELF3,EMX1,ENDOG,EOMES,EPAS1,EPB41L5,EPN1,ERCC2,ETNK2,FBXW8,FGFR1,FGFR2,FLCN,FLVCR1,FOSL1,FOXC1,FOXF1,FUT8,FZD5,GABPA,GATA2,GATA3,GATA6,GCM2,GDF3,GGNBP2,GINS1,GINS4,GJB3,GJB5,GLI2,GLI3,GNA12,GNA13,GRB2,GRHL2,HAND1,HAND2,HEG1,HES1,HES3,HEY1,HEY2,HHEX,HIF1A,HINFP,HNF1B,HS6ST1,HSD17B2,HSF1,IFITM5,IGF2,IHH,IL10,INPP5B,INPP5K,ITGB1,JAG2,JUNB,KDM4C,KDM6A,KEAP1,KLF2,KRT19,LATS1,LEF1,LIF,LIG4,MAFF,MAFG,MAN2A1,MAPK1,MBD3,MBNL1,MDFI,MED21,MFN2,MIB1,MSH2,MSX1,MYH6,MYH9,MYO1E,NASP,NBN,NCAPG2,NCOA1,NDEL1,NLE1,NMT1,NOG,NOS3,NOTCH1,NSDHL,OCRL,OOEP,OVOL2,PALB2,PCDH12,PCGF2,PDGFB,PITX2,PKD1,PKD2,PLAC1,PLCD3,PLCG1,PLG,PLK4,POLG2,PRDM1,PRPF19,PSMC3,PSMC4,PTCH1,PTPRR,PYGO2,RARRES2,RBBP8,RBM46,RBPJ,RDH10,RIC8A,RNASEH2B,RPL7L1,RRN3,RRP7A,RSPO3,RTF1,RXRA,SBDS,SEC24D,SETD2,SF3B6,SKIL,SLC30A1,SLC34A2,SLC39A3,SMAD2,SMAD4,SMO,SNAI1,SOCS3,SOX10,SOX17,SOX18,SOX8,SPIC,SPINT1,SRF,SRSF1,ST14,STIL,STK4,TAB1,TAF8,TANC2,TAPT1,TBX3,TFEB,TGFBR1,TGFBR2,THOC2,TIE1,TMED2,TMEM100,TMEM231,TRIM28,TTPA,TWIST1,UBTFL1,VASH1,VASH2,VEGFA,WDTC1,WNT3A,WNT7B,WNT9B,XAB2,XRCC2,YBX1,YBX3,ZFAND5,ZFAT,ZFP36L1,ZFPM2,ZMIZ1,ZNF335,ZNF830,ZP3,ZPR1	TetrapodAncestor	106.9
GO.Biological.Process	GO:0060562	epithelial.tube.morphogenesis	302	9.888386e-112	1.277283e-107	4.229413e-110	1.191401e+0	ABL1,ACVRL1,ADAMTS16,AHI1,ALX1,APAF1,AR,AREG,ARHGAP35,ARID1A,ARL13B,B4GALT1,BBS4,BBS7,BCL10,BCL2,BMP2,BMP4,BMP5,BMP7,BTRC,C2CD3,CASR,CCDC103,CCDC40,CCL11,CCM2,CELSR1,CFL1,CITED1,COBL,CSF1,CSF1R,CSNK2B,CTNNB1,CTSH,CTSZ,DCHS1,DDR1,DEAF1,DLC1,DLG1,DLG5,DLL1,DLL4,DNAAF1,DVL1,DVL3,EDN1,EFNB2,EGF,ENG,EPHA2,EPHA4,EPHA7,ESR1,ESRP2,EYA1,FAT4,FGF1,FGF10,FGF2,FGFR2,FMN1,FOXA1,FOXC2,FOXF1,FOXH1,FOXN4,FUZ,FZD1,FZD2,FZD3,FZD6,GATA3,GATA4,GBX2,GDF2,GDNF,GLI2,GLI3,GNA13,GPC3,GREM1,GRHL2,GRHL3,GZF1,HAND1,HAND2,HES1,HES5,HHEX,HIF1A,HNF1B,IFT172,IFT52,IFT57,IHH,KDM2B,KDM5B,KDM6A,KIF20B,KIF26B,KLHL3,KRAS,LAMA5,LBX1,LEF1,LGR4,LGR5,LHX1,LHX2,LMO4,LRP5,LRP6,LUZP1,MEF2C,MEGF8,MESP1,MET,MIB1,MKKS,MKS1,MMP14,MSX2,MTHFD1,MTHFD1L,MTSS1,MYC,MYCN,NDRG4,NFATC4,NKX2-5,NKX3-1,NOG,NOTCH1,NOTCH4,NOTO,NPHP3,NRP1,OSR1,OVOL2,PAK1,PAX2,PAX8,PBX1,PFN1,PGR,PHACTR4,PITX2,PKD1,PKD2,PLXNB2,PLXND1,PML,PODXL,PRICKLE1,PRKACA,PRKD2,PRKX,PSEN1,PTCH1,PTK7,RALA,RARA,RARG,RASIP1,RBPJ,RDH10,RET,RSPO2,RYR2,SCRIB,SDC4,SEC24B,SEMA3E,SEMA4C,SETD2,SETDB2,SFRP1,SFRP2,SHROOM3,SKI,SLIT2,SMAD4,SMO,SOSTDC1,SOX11,SOX17,SOX18,SOX4,SOX8,SOX9,SPINT1,SPRY1,SPRY2,SRC,SRF,ST14,STARD13,STIL,STK4,SUFU,T,TACSTD2,TBX2,TBX20,TBX3,TCF21,TEAD2,TGFB1,TGFB2,TGFBR2,TIMELESS,TMED2,TNC,TRAF6,TRIM71,TSC2,TULP3,TWIST1,VANGL2,VASP,VDR,VEGFA,WNK4,WNT1,WNT11,WNT3A,WNT4,WNT5A,WNT6,WNT9B,ZIC3	TetrapodAncestor	106.894
GO.Biological.Process	GO:0051046	regulation.of.secretion	303	9.792969e-111	1.264958e-106	4.174778e-109	1.143581e+0	AACS,ABAT,ABCC8,ABL1,ABR,ACHE,ACSL3,ADA,ADAM8,ADAM9,ADCY5,ADCYAP1,ADGRE2,ADIPOQ,ADORA1,ADORA2A,ADORA2B,ADRA2A,ADRA2B,ADRA2C,AGT,AGTR1,AGTR2,ALOX15B,ANGPT1,ANKRD1,ANO1,ANXA1,ANXA4,AP1G1,APLN,APOA1,APOA2,AQP1,ARF1,ARFIP1,ARG2,ARHGEF7,ARL2,ARL2BP,ARNTL,ARRB1,ASIC1,ATG5,ATP13A2,ATP6AP1,AVP,AVPR1A,AVPR2,BAD,BANK1,BCR,BLK,BMP6,BMP8A,BRAF,BRSK2,C12orf4,C1QTNF1,C1QTNF12,C1QTNF3,C2CD2L,C5,CACNA1A,CACNA1C,CACNA1D,CACNA1E,CACNA1G,CACNA1H,CACNA1I,CACNA2D2,CADM1,CADPS2,CAMK2A,CAPN10,CARD16,CARD17,CARD18,CARTPT,CASP1,CASP5,CASR,CCK,CCKAR,CCL19,CCL3,CCL5,CCR2,CCR7,CD14,CD2,CD274,CD300A,CD34,CD38,CD40,CD58,CD74,CDK16,CDK5,CDK5R2,CFTR,CHD7,CHGA,CHIA,CHMP2A,CHRNA3,CHRNA6,CHRNB2,CHRNB4,CHUK,CIDEA,CLASP1,CLASP2,CLEC4E,CLEC6A,CLEC9A,CNR1,CORIN,CPB2,CPLX1,CPLX2,CPLX3,CPLX4,CPT1A,CREB1,CRHBP,CRHR1,CRTAM,CRY1,CSF1R,CYBA,CYP19A1,CYP4A11,DCANP1,DDX58,DHX9,DISP1,DNAJC1,DNM1L,DOC2A,DOC2B,DPH3,DRD2,DRD3,DRD4,DTNBP1,EDN1,EDN3,EDNRB,EFNA5,EGF,EGFR,ENSG00000173366,EPHA5,ERP29,EXPH5,EZR,F2R,F2RL1,FAM3D,FCER1G,FCN1,FER,FERMT1,FES,FFAR1,FFAR2,FFAR3,FFAR4,FGF10,FGF20,FGF23,FGFR1,FGG,FGR,FKBP1B,FMR1,FN1,FOXA2,FOXF1,FOXP3,GAB2,GAL,GAPDH,GAS6,GATA2,GATA3,GCK,GDNF,GHRH,GHRHR,GHSR,GIP,GIPR,GJA1,GLP1R,GLUD1,GLUL,GNAS,GOLPH3,GPAM,GPER1,GPLD1,GPR68,GRIK5,GRK2,GRM7,GRP,GSDMD,HAP1,HAVCR2,HGS,HIF1A,HIP1R,HMGB1,HMGCR,HMGN3,HMHB1,HMOX1,HNF4A,HRH3,HTR1A,HTR1B,HTR2A,HTR2B,HTR2C,ICA1,IDH2,IFNA2,IFNAR1,IFNG,IGF1,IL10,IL13,IL13RA2,IL17A,IL17F,IL17RA,IL17RB,IL17RC,IL1A,IL1B,IL1R2,IL1RAP,IL1RAPL1,IL1RL1,IL2,IL26,IL33,IL36RN,IL4,IL5,IL6,INHA,INHBA,INHBB,INS,IRF3,IRS1,IRS2,ISL1,ITGAM,ITGB2,ITPR1,ITPR2,ITPR3,JAGN1,JAK2,KALRN,KARS,KCNA2,KCNA5,KCNB1,KCNC2,KCNG2,KCNJ11,KCNMB4,KCNQ1,KCNS3,KDM5B,KIF5B,KISS1,KRT20,LACRT,LEP,LGALS9,LGI3,LGR4,LIF,LLGL2,LPL,LRP5,LRRC32,LRRK2,LYN,MAOB,MAP2K6,MAP4K4,MAPK11,MAPK14,MAPK3,MARCKS,MCTP1,MCU,MEF2C,MICAL1,MIF,MMP12,MPC2,MTNR1B,MYB,MYO18A,MYO6,MYRIP,NAPA,NCS1,NDUFAF2,NEUROD1,NEUROG1,NF1,NKX3-1,NKX6-1,NLGN1,NLRP1,NLRP10,NLRP2,NLRP6,NLRP7,NNAT,NOS2,NOTCH1,NOV,NPFF,NPHS1,NPR1,NPVF,NPY2R,NPY5R,NR0B2,NR1D1,NR1H2,NR1H3,NR1H4,NRG1,NRXN1,NSF,NTSR1,OPRK1,OPRL1,OPRM1,OR51E2,OR56A1,OR56A4,OR5T3,ORM1,ORM2,OSM,OXCT1,OXT,OXTR,P2RX4,P2RX7,P2RY1,P2RY2,P3H1,PAEP,PAM,PANX1,PASK,PAX8,PCK2,PCLO,PDCD6IP,PDE8B,PDPK1,PER2,PFKFB2,PFKL,PFN2,PHPT1,PIK3C3,PIM3,PINK1,PLA2G10,PLA2G1B,PLA2G6,PLAA,PML,PNKD,POFUT2,POMC,PPARD,PPP3CA,PPP3CB,PRAM1,PRKCA,PRKCE,PRKCZ,PRKN,PSMD9,PTAFR,PTGER3,PTGER4,PTPN11,PTPN22,PTPN23,PYCARD,PYDC1,PYDC2,RAB11FIP1,RAB11FIP5,RAB15,RAB21,RAB26,RAB27A,RAB27B,RAB2B,RAB33B,RAB37,RAB3B,RAB3C,RAB3D,RAB3GAP1,RAB5A,RAB7A,RAB8A,RAB8B,RAC2,RALA,RALB,RAP1A,RAP1B,RAPGEF3,RASGRP1,RASL10B,RBP4,REN,REST,RETN,RFX3,RFX6,RGCC,RHBDD3,RHBDF1,RHBDF2,RIMS1,RIMS3,RIMS4,RIPK2,RPH3A,RPH3AL,RSAD2,RSG1,S100A8,SAA1,SCAMP5,SCG5,SCIN,SCT,SDC4,SDCBP,SELENOK,SELENOT,SEPT5,SERGEF,SERP1,SFRP1,SGK1,SIDT2,SIRT3,SIRT4,SLC16A1,SLC25A5,SLC25A6,SLC2A1,SLC2A2,SLC30A1,SLC30A8,SLC6A4,SLC8B1,SLC9A3R1,SLC9B2,SMAD4,SMPD3,SNAP25,SNCA,SNCAIP,SNCG,SNF8,SNX4,SOCS1,SOX11,SOX4,SPP1,SPX,SRC,SRCIN1,SREBF1,SRI,SSC5D,SSTR5,STAM,STC1,STX1A,STX1B,STX4,STXBP1,STXBP2,STXBP4,STXBP5,STXBP5L,STXBP6,STYK1,SV2A,SYBU,SYK,SYN1,SYT1,SYT10,SYT11,SYT13,SYT15,SYT17,SYT2,SYT4,SYT5,SYT6,SYT7,SYT8,SYT9,SYTL1,SYTL2,SYTL3,SYTL4,SYTL5,TAC1,TAC4,TARDBP,TFAP2B,TFR2,TGFB1,TGFB2,TIAM1,TIFAB,TLR1,TLR10,TLR2,TLR4,TLR5,TLR6,TLR9,TM7SF3,TMBIM6,TMEM27,TNF,TNFRSF11A,TNFRSF14,TNFRSF21,TNFRSF4,TNFRSF9,TNFSF11,TRAF2,TRAF6,TRIM6,TRIM9,TRPM4,TRPV1,TRPV6,TSG101,TTN,TWIST1,UCN,UCN3,UCP2,UNC13A,UNC13B,UQCC2,UTS2,UTS2R,VAMP2,VAMP3,VAMP8,VEGFC,VPS35,VPS4A,VPS4B,VSNL1,VTCN1,WLS,WNK1,WNK3,WNK4,WNT5A,XBP1,ZC3H12A,ZP3	TetrapodAncestor	105.898
GO.Biological.Process	GO:2000045	regulation.of.G1/S.transition.of.mitotic.cell.cycle	304	2.239105e-110	2.892252e-106	9.513987e-109	1.370375e+0	AIF1,ANKRD17,ANXA1,APEX1,ATM,AURKA,BAX,BCL2,BID,BTG2,CARM1,CASP2,CCL2,CCNB1,CCND1,CCND2,CDC25C,CDC45,CDC6,CDC73,CDK1,CDK10,CDK2,CDK2AP2,CDKN1A,CDKN1B,CDKN2B,CENPJ,CHEK2,CNOT1,CNOT10,CNOT11,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT8,CRADD,CTDSP1,CTDSP2,CTDSPL,CUL4A,CYP1A1,DACT1,DCUN1D3,DDX3X,E2F1,E2F4,E2F7,E2F8,ECD,EGFR,EP300,EZH2,FBXO31,FBXO7,FGF10,GADD45A,GIGYF2,GJC2,GML,GPNMB,GTSE1,ID2,INO80,JADE1,KANK2,KCNA5,LSM11,MDM2,MDM4,MEPCE,MTBP,MUC1,MYO16,NPM1,PCBP4,PCNA,PDPN,PID1,PIDD1,PKD1,PKD2,PLAGL1,PLCB1,PLK2,PLK3,PLK5,PML,PRKDC,PRMT1,PSME1,PSME2,PSME3,PTEN,RB1,RDX,RFWD3,RGCC,RPA2,RPS27A,RPS27L,RPTOR,SFN,SLFN11,SMARCA4,SOX4,TERT,TFDP2,TNKS1BP1,TP53,TP63,TP73,TRIAP1,UBC,UBE2E2,ZNF385A	TetrapodAncestor	105.539
GO.Biological.Process	GO:1901991	negative.regulation.of.mitotic.cell.cycle.phase.transition	305	2.832713e-110	3.659015e-106	1.199677e-108	1.344683e+0	APC,ATM,AURKA,AURKB,BAX,BCL2,BRCA1,BTG2,BUB1,CARM1,CASP2,CCNB1,CCND1,CDC25C,CDC73,CDK1,CDK2,CDK2AP2,CDKN1A,CDKN1B,CDKN2B,CENPF,CENPJ,CHEK2,CHMP4C,CNOT1,CNOT10,CNOT11,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT8,CRADD,CTDSP1,CTDSP2,CTDSPL,CUL1,DACT1,DCUN1D3,DONSON,E2F1,E2F4,E2F7,E2F8,EP300,EZH2,FANCI,FBXL7,FBXO31,FBXO7,FOXN3,FOXO4,GADD45A,GIGYF2,GJC2,GML,GPNMB,GPR132,GTSE1,HMGA2,HUS1,HUS1B,IK,JADE1,KANK2,KLHL22,MAD1L1,MAD2L1,MAD2L2,MDM2,MDM4,MIIP,MRE11,MRNIP,MUC1,MUS81,MYO16,NAE1,NBN,NOP53,NPM1,ORAOV1,PCBP4,PCNA,PIDD1,PINX1,PKD2,PLAGL1,PLK1,PLK2,PLK3,PML,PRKDC,PRMT1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTEN,RAD17,RAD21,RB1,RFWD3,RGCC,RPA2,RPS27A,RPS27L,SFN,SLFN11,SMARCA4,SOX4,TEX14,TFDP2,TICRR,TNKS1BP1,TOPBP1,TP53,TP63,TP73,TPR,TPRA1,TRIAP1,TRIP13,TTK,UBC,USP47,VPS4A,ZFP36L1,ZFP36L2,ZFYVE19,ZNF207,ZNF385A,ZNF830,ZW10	TetrapodAncestor	105.437
GO.Biological.Process	GO:0051701	interaction.with.host	306	4.780548e-110	6.175034e-106	2.017985e-108	1.386526e+0	ACE2,ALB,ANPEP,AXL,BAD,BCL2L1,BCL2L11,C9,CASP8,CAV1,CAV2,CBL,CBLL1,CCNK,CCR5,CD209,CD46,CD55,CD80,CD81,CD86,CDH1,CDHR3,CDK1,CLDN1,CLDN6,CLDN9,CLEC4G,CLEC4M,CPSF4,CR1,CR2,CTNNB1,CTNND1,CTSB,CXADR,CXCR4,DYNLT1,EFNB2,EFNB3,EGFR,EIF2AK2,EIF2AK4,EPHA2,EPS15,F11R,GAPDH,GAS6,GRB2,GRK2,GUCY1A3,HAVCR1,HIPK2,HTR2A,IDE,IFIT1,IST1,ITCH,ITGA2,ITGA5,ITGAV,ITGB1,ITGB5,ITGB7,KPNA1,KPNA2,KPNA3,KPNA4,KPNA5,KPNA7,KPNB1,LDLR,MET,MRC1,NCAM1,NECTIN1,NECTIN2,NECTIN4,NPC1,NTRK3,NUP153,PABPN1,PRKN,PTX3,RAB7A,RPS27A,RPSA,RRAGA,RXRA,SCARB1,SCARB2,SCRIB,SERPINB3,SERPINB9,SLC10A1,SLC1A5,SLC22A5,SLC25A6,SLC52A1,SLC52A2,SRC,SUGT1,TCP1,TFRC,TGFB1,TNFRSF14,TNFRSF4,TNIP1,TYMS,TYRO3,UBC,UVRAG,VAMP8,VAPA,VAPB,VPS18,VPS4A,VPS4B,WWP1,WWP2,XPR1,ZC3H12A,ZNF639	TetrapodAncestor	105.209
GO.Biological.Process	GO:0010801	negative.regulation.of.peptidyl-threonine.phosphorylation	307	1.024638e-109	1.323525e-105	4.311156e-108	1.906511e+0	CALM1,CALM2,CALM3,DDIT4,DGKQ,DMTN,INPP5K,PARD3,PPEF2,SIRT2,SMAD7,SPRED1,SPRED2,SPRY2	TetrapodAncestor	104.878
GO.Biological.Process	GO:0061440	kidney.vasculature.development	308	1.677614e-109	2.166974e-105	7.035630e-108	1.776761e+0	ACTA2,ANGPT1,ANGPT2,AQP1,BMP4,CD34,EGR1,FOXC2,GPR4,HES1,NOTCH1,NOTCH3,NRP1,OSR1,PDGFB,PDGFRB,PECAM1,PKD2,TCF21,TEK	TetrapodAncestor	104.664
GO.Biological.Process	GO:0060485	mesenchyme.development	309	1.740441e-109	2.248128e-105	7.275494e-108	1.221140e+0	ACTA2,ACTG2,ACVRL1,ADAM15,ALX1,AMELX,AMER1,AMH,BASP1,BCL2,BMP2,BMP4,BMP5,BMP7,BMPR1A,BMPR2,CFL1,CITED2,CRELD1,CTNNB1,CUL7,CYP26C1,DAND5,DCHS1,DDX17,DDX5,DLG5,DLL3,DPPA2,DPPA4,EDN1,EDN3,EDNRB,EFNA1,EFNB1,ENG,EOMES,EPB41L5,ERBB4,ERG,EXOC4,FAM83D,FGF10,FGF19,FGF9,FGFR1,FGFR2,FOXC1,FOXC2,FOXF1,FOXF2,FOXH1,GATA4,GBX2,GDNF,GSC,HAND1,HAND2,HAS2,HES1,HEY1,HEY2,HEYL,HGF,HIF1A,HMGA2,HNRNPAB,HTR2B,ISL1,JAG1,KBTBD8,KITLG,KLHL12,LAMA5,LEF1,LOXL2,LOXL3,LRP6,MAPK1,MAPK3,MDM2,MEF2C,MEOX1,MESP1,MSX1,MSX2,NKX2-5,NOG,NOLC1,NOTCH1,NRG1,NRP1,NRTN,OLFM1,OSR1,OVOL2,PAX2,PDCD6,PDGFRB,PEF1,PHACTR4,PHOX2B,PITX2,PKD2,POGLUT1,PTK7,RANBP3L,RBPJ,RDH10,RET,RFLNB,RTN4,S100A4,SCX,SEMA3A,SEMA3C,SFRP1,SFRP2,SIX2,SMAD2,SMAD4,SMO,SNAI1,SNAI2,SOX10,SOX11,SOX8,SOX9,SPRY1,STAT1,TAPT1,TBX1,TBX2,TBX20,TBX5,TCF15,TCF21,TCOF1,TEAD2,TGFB1,TGFB2,TGFBR1,TGFBR2,TMEM100,TRIM28,TSPY2,TWIST1,WNT10A,WNT11,WNT16,WNT3A,WNT4,WNT5A,WNT8A,WWTR1,ZFP36L1,ZFPM2	TetrapodAncestor	104.648
GO.Biological.Process	GO:0060759	regulation.of.response.to.cytokine.stimulus	310	2.072991e-109	2.677682e-105	8.637685e-108	1.346363e+0	ADAR,ADIPOQ,AES,AGPAT1,AGPAT2,ANGPT1,APOA1,ARG1,AXL,BIRC2,BIRC3,CACTIN,CARD16,CASP1,CASP4,CASP8,CAV1,CBFB,CCDC3,CCL5,CD24,CD300LF,CD74,CHUK,CLIP3,CREBRF,CSF1,DCST1,DDX58,DHX9,EDN1,ELF1,F2RL1,FADD,GAS6,GSTP1,HIF1A,HIPK1,HSP90AB1,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNAR1,IFNAR2,IFNB1,IFNG,IFNGR1,IFNGR2,IKBKB,IKBKG,IL1R1,IL1R2,IL1RN,IL36RN,IL6,IRAK1,IRAK3,IRF3,IRF7,IRGM,JAK2,KLF4,LIFR,MADD,MMP12,MUL1,NLRC5,NOL3,NR1H2,NR1H3,NR1H4,OTULIN,PADI2,PAFAH1B1,PALM3,PARP14,PARP9,PELI3,PIAS1,PIAS4,PPARG,PRKN,PTPN1,PTPN11,PXDN,PYCARD,PYDC1,PYDC2,RBCK1,RFFL,RIPK1,RIPK2,RNASEL,RNF31,ROBO1,RPS27A,RUNX1,SCRIB,SHARPIN,SIGIRR,SLIT2,SLIT3,SOCS1,SOCS3,SPHK1,SPPL2A,SPPL2B,STAP1,STAT1,STAT2,SUMO1,SYK,TAF9,TAX1BP1,TICAM2,TNF,TNFAIP3,TNFRSF1A,TRADD,TRAF1,TRAF2,TRAIP,TREM2,TRIM32,TRIM44,TRIM6,TXK,UBC,USP18,VRK2,WNT5A,ZNF675	TetrapodAncestor	104.572
GO.Biological.Process	GO:0048878	chemical.homeostasis	311	2.728467e-109	3.524361e-105	1.133235e-107	1.132502e+0	AACS,ABCA1,ABCA12,ABCA2,ABCB4,ABCB6,ABCB7,ABCC2,ABCC8,ABCG1,ABCG2,ABL1,ABL2,ACACA,ACO1,ACSM1,ACSM2A,ACSM3,ADCY2,ADCY3,ADCY4,ADCY5,ADCY8,ADCYAP1,ADGRF5,ADIPOQ,ADIPOR1,ADIPOR2,ADNP,ADRA1A,ADRA1B,ADRA1D,ADRA2A,AFG3L2,AGER,AGT,AGTR1,AGTR2,AKR1B1,ANGPTL4,ANGPTL8,ANK2,ANK3,ANXA6,APOA1,APOA2,APOA4,APOA5,APOB,APOC3,APOE,APOM,APP,AQP1,AQP11,AQP2,AQP3,AQP4,ARF1,ASPSCR1,ATOX1,ATP12A,ATP13A2,ATP13A4,ATP13A5,ATP1A1,ATP1A2,ATP1A4,ATP1B1,ATP1B2,ATP1B3,ATP2A1,ATP2B1,ATP2B2,ATP2B3,ATP2B4,ATP6AP1,ATP6V0A4,ATP6V0B,ATP6V0C,ATP6V0D1,ATP6V0D2,ATP6V0E1,ATP6V0E2,ATP6V1B1,ATP6V1B2,ATP6V1C1,ATP6V1C2,ATP6V1D,ATP6V1E1,ATP6V1E2,ATP6V1G1,ATP6V1G3,ATP6V1H,ATP7B,AVP,AVPR1A,AVPR1B,AVPR2,BAD,BAK1,BAX,BCAP31,BCL2,BDH2,BDKRB1,BDKRB2,BECN2,BHLHA15,BMP6,BNIP3,BPIFA1,BTBD9,C19orf12,C1QTNF1,C1QTNF3,C3AR1,C7,CA12,CA2,CA7,CACNA1A,CACNA1C,CACNA2D1,CALB1,CALB2,CALR,CAMK2D,CAND1,CAPS2,CARTPT,CASQ2,CASR,CATSPER4,CAV1,CAV3,CCDC22,CCDC47,CCKAR,CCKBR,CCL1,CCL11,CCL13,CCL14,CCL15,CCL19,CCL2,CCL21,CCL23,CCL28,CCL3,CCL5,CCL7,CCL8,CCR1,CCR2,CCR3,CCR4,CCR5,CCR6,CCR7,CCR8,CCR9,CD24,CD36,CD38,CD40,CD52,CD55,CDH23,CEBPA,CETP,CFTR,CHERP,CHP1,CHRNA10,CHRNA9,CIB2,CLCN3,CLDN1,CLDN16,CLDN4,CLN3,CLN6,CNGB1,CNNM4,CNR1,COMMD1,COMMD9,COX11,CP,CPB2,CPS1,CRY1,CRY2,CSRP3,CTSH,CUL1,CUTC,CXCL13,CXCR3,CXCR4,CYB5R4,CYBA,CYP11B1,CYP11B2,CYP26B1,CYP27B1,CYP4A11,CYP7A1,DBH,DDB1,DGAT1,DGAT2,DHPS,DISC1,DISP3,DLG4,DMPK,DMXL1,DMXL2,DRD1,DRD2,DRD3,DRD4,DRD5,DYNLT1,EDN1,EDN2,EDN3,EDNRB,EGFR,EGLN1,EHD1,EIF5A2,ENDOG,ENPP1,EPAS1,EPHX2,ERFE,ERN1,ERO1A,ERO1B,ESR1,F2,F2R,F2RL1,F2RL3,FABP3,FABP4,FAM155A,FAM155B,FAM20A,FASLG,FBXL5,FBXW7,FFAR1,FFAR2,FGF2,FGF21,FGF23,FGFR4,FIS1,FITM2,FKBP1A,FKBP1B,FLG,FLG2,FLVCR1,FOXA1,FOXA3,FOXO1,FTH1,FTHL17,FTL,FTMT,FXN,FZD9,G6PC,GALR2,GAS6,GATA2,GATA4,GBA,GCGR,GCK,GCKR,GCLM,GCM2,GDF2,GHRHR,GIP,GIPR,GJA1,GLP1R,GNA13,GNA15,GNG3,GOT1,GPAM,GPCPD1,GPER1,GPIHBP1,GPR157,GPR17,GPR18,GPR20,GPR21,GPR32,GPR33,GPR35,GPR4,GPR55,GPR65,GRHL3,GRIA1,GRIK2,GRIK5,GRIN1,GRIN2A,GRIN2B,GRIN2C,GRIN2D,GRINA,GRM5,GSTP1,GTF2I,HACD3,HAMP,HAS2,HCRTR1,HCRTR2,HECTD4,HEPH,HERPUD1,HFE2,HIF1A,HK3,HMGB1,HMOX1,HMOX2,HNF1A,HNF4A,HOMER1,HRC,HRNR,HSP90B1,HTR2A,HTR2B,HTR2C,IAPP,IBTK,IFIT1,IGFBP5,IL18,IL2,IL6,IMMT,INPP5K,INS,IREB2,IRS1,IRS2,ITGAV,ITPR1,ITPR2,ITPR3,JAK2,JPH1,JPH2,JPH3,JPH4,KCNA1,KCNA5,KCNB1,KCNH2,KCNJ10,KCNJ11,KCNJ2,KCNK3,KCNMA1,KCTD17,KDF1,KEL,KISS1,KL,KLHL3,KNG1,KRT1,KRT16,LCAT,LCK,LCN2,LDLR,LDLRAP1,LEP,LEPR,LETM1,LETM2,LGALS1,LIN28A,LIPG,LPAR1,LPAR3,LPAR4,LPAR6,LPL,LRP5,LRP6,LRRK2,MAFG,MAIP1,MALL,MALRD1,MAPK1,MAPK3,MC3R,MCHR1,MCOLN1,MCU,MCUB,MCUR1,MED13,MELTF,MEN1,MET,MICU1,MICU2,MLXIPL,MTNR1B,MYC,MYLIP,MYO5B,NAPSA,NARFL,NCOA4,NCOA5,NDFIP1,NEDD4L,NEDD8,NEO1,NEUROD1,NGFR,NME1,NME2,NMUR2,NOL3,NOX4,NPC1,NPC2,NPFF,NPTN,NPY2R,NR1D2,NR1H2,NR1H3,NR1H4,NR5A2,NUBP1,NUCKS1,NUS1,OAS1,OGT,OIT3,OPA1,OPRL1,OR56A1,OR56A4,OR5T3,ORMDL1,ORMDL2,ORMDL3,OTC,OXT,OXTR,P2RX7,P2RY1,P2RY10,P2RY2,P2RY4,P2RY8,PARK7,PAX2,PCK1,PCK2,PDE6A,PDE6B,PDK2,PDK3,PICALM,PIK3CA,PIK3CG,PIK3R1,PIK3R2,PKD1,PKD2,PKHD1,PKP2,PLA2G10,PLA2G6,PLCE1,PLCG2,PLN,PML,PNPLA1,PNPLA2,PNPLA3,PNPLA4,PNPLA5,POLD1,POMC,POU3F3,PPARG,PPARGC1A,PPP3CA,PPT1,PQLC2,PRCP,PRKAA1,PRKAA2,PRKACA,PRKACG,PRKAR1A,PRKAR1B,PRKAR2B,PRKCB,PRKCE,PRKN,PROK2,PSEN1,PTCH1,PTH,PTH1R,PTK2B,PTPN11,PTPRN2,PVALB,RAB11B,RAB11FIP2,RAB11FIP5,RAB38,RAB39A,RAB7A,RAF1,RANBP2,RAP1A,RAP1GDS1,RASA3,RBP1,RBP4,RFX6,RGN,RHAG,RHCG,RIC3,RMDN3,RPH3AL,RPS27A,RPS6,RXFP3,RYR1,RYR2,RYR3,S100A14,S100A8,S100A9,S1PR1,S1PR3,S1PR4,SAA1,SCARA5,SCARB1,SCGN,SCNN1A,SCNN1B,SCNN1G,SCO1,SCO2,SELENOK,SELENON,SELENOT,SESN2,SESN3,SFN,SFRP4,SFXN1,SFXN2,SFXN3,SFXN4,SFXN5,SIDT2,SIRT1,SIRT6,SLC11A1,SLC12A5,SLC16A1,SLC17A7,SLC22A17,SLC24A2,SLC24A3,SLC24A4,SLC24A5,SLC25A23,SLC25A27,SLC25A28,SLC25A37,SLC26A1,SLC26A10,SLC26A11,SLC26A2,SLC26A3,SLC26A4,SLC26A5,SLC26A7,SLC26A8,SLC26A9,SLC29A1,SLC30A1,SLC30A4,SLC30A5,SLC30A7,SLC30A8,SLC30A9,SLC31A1,SLC31A2,SLC34A1,SLC34A2,SLC34A3,SLC39A10,SLC39A12,SLC39A13,SLC39A14,SLC39A4,SLC39A7,SLC39A8,SLC40A1,SLC41A1,SLC46A1,SLC4A1,SLC4A11,SLC4A2,SLC4A3,SLC4A4,SLC4A5,SLC4A7,SLC4A9,SLC7A8,SLC8A1,SLC8A2,SLC8A3,SLC8B1,SLC9A1,SLC9A2,SLC9A3,SLC9A3R1,SLC9A4,SLC9A5,SLC9A7,SLC9A8,SLC9A9,SLC9B1,SMAD4,SMDT1,SNAPIN,SOAT1,SOAT2,SOD1,SOD2,SOX4,SPOP,SPPL3,SRF,SRI,SSTR5,STAR,STAT1,STAU1,STC1,STC2,STEAP1,STEAP2,STEAP3,STEAP4,STIM1,STIM2,STMN1,STXBP5L,SV2A,TAC1,TAC4,TBC1D20,TBXA2R,TCIRG1,TESMIN,TF,TFAP2B,TFR2,TFRC,TGFB1,TGM2,TH,TM9SF4,TMBIM6,TMC8,TMCO1,TMEM175,TMEM178A,TMEM199,TMEM203,TMEM64,TMEM79,TMEM97,TMPRSS3,TMPRSS6,TMTC2,TNFSF11,TNNI3,TP63,TPCN1,TPCN2,TPT1,TRA2B,TRDN,TRIM24,TRPA1,TRPC1,TRPC5,TRPC6,TRPC7,TRPM1,TRPM2,TRPM4,TRPM7,TRPM8,TRPV1,TRPV5,TRPV6,TTC7A,TTPA,UBC,UCP2,UMOD,UNC13B,UPK3A,USF1,USF2,UTS2,UTS2R,VAPB,VDR,VEGFA,WDR35,WDTC1,WFS1,WNK4,WNT7B,XBP1,XCL1,XCR1,XIAP,XK,XPR1,YWHAE	TetrapodAncestor	104.453
GO.Biological.Process	GO:0051259	protein.oligomerization	312	4.400618e-109	5.684278e-105	1.821884e-107	1.198182e+0	AASS,ACACA,ACACB,ACADL,ACAT1,ACHE,ACMSD,ACOT13,ACPP,ACVRL1,ADIPOQ,ADSL,AHNAK,ALAD,ALDH1A3,ALDH5A1,ALDOA,ALOX5AP,AMFR,ANGPTL4,ANXA6,APAF1,APC,APIP,AQP11,AR,ARG1,ASIC1,ATG16L1,ATL2,ATL3,ATPIF1,ATXN10,B4GALT1,BAG4,BAX,BCL10,BID,BIRC2,BIRC3,BRAF,C1QL2,C1QTNF1,C1QTNF2,C1QTNF3,C1QTNF5,C1QTNF6,C9,CAB39,CALHM1,CAMK2D,CAMK2G,CAT,CAV1,CAV2,CBR4,CBY1,CCDC88C,CCL5,CD247,CD3D,CD3E,CD3G,CD74,CD79B,CDA,CEP57,CHMP2A,CHMP3,CHMP4A,CHMP4B,CHP1,CHRNA2,CHRNB2,CHRNB3,CHRNB4,CLDN1,CLDN3,CLPP,CNGB1,COL1A1,COL1A2,COL6A1,COL6A2,COLEC12,CPSF6,CPSF7,CPT1A,CRTC3,CRYAA,CRYAB,CRYZ,CTH,CTNNA1,CUTC,DCXR,DECR1,DERL1,DFFB,DGKD,DHPS,DHRS4,DISP1,DNM1,DNM1L,DPAGT1,DPYSL3,DYNC1LI2,ECT2,EHD1,EHD3,EHD4,EIF2AK3,EMILIN1,ENSG00000151079,EPPIN,EPPIN-WFDC6,EVL,FARSA,FAS,FBP1,FCER1G,FGFRL1,FIS1,FLOT1,GCH1,GCHFR,GJA1,GLRA1,GLRA3,GLRB,GLUL,GNMT,GOLGA2,GOPC,GPX3,GRB2,GRHPR,GRIN1,GRIN2B,GSDMD,HACL1,HBA1,HBA2,HBB,HBE1,HCN1,HIST1H3H,HIST1H3I,HIST1H3J,HIST1H4J,HIST1H4K,HIST1H4L,HIST2H4B,HIST4H4,HM13,HMGCL,HMGCR,HMOX1,HPRT1,HRAS,HSCB,HSD17B8,HSF1,HSF4,HTRA2,IAPP,IDE,IGF1R,IGHMBP2,IKBKE,IKZF1,IKZF4,IRAK1,ITPR3,JUP,KCNA1,KCNA10,KCNA2,KCNA3,KCNA4,KCNA5,KCNA7,KCNB1,KCNB2,KCNC1,KCNC2,KCNC3,KCND1,KCND2,KCNF1,KCNG1,KCNG2,KCNG3,KCNG4,KCNJ12,KCNJ2,KCNRG,KCNS1,KCNS3,KCNV1,KCNV2,KCTD1,KCTD12,KCTD13,KCTD14,KCTD15,KCTD16,KCTD17,KCTD18,KCTD19,KCTD2,KCTD21,KCTD3,KCTD4,KCTD5,KCTD6,KCTD7,KCTD8,KCTD9,KHDRBS1,KHDRBS3,KIF25,LCN2,LETM1,LNX1,LONP1,LRP4,LY6G5B,MAGI2,MALT1,MAPT,MARCKS,MAT2A,MCCC1,MCCC2,MCOLN2,ME1,MFF,MGST1,MICU1,MIF,MLC1,MLKL,MPP2,MTMR2,MUC20,NAXE,NBR1,NLGN1,NLRC4,NME2,NOD1,NOL3,NPM1,NPM2,NUFIP1,NUP54,NUP58,NUP62,OLFM4,OPA1,OTC,OXA1L,P2RX2,P2RX3,P2RX4,P2RX6,P2RX7,PAM,PANX1,PANX2,PANX3,PCBD1,PDCD6IP,PDSS2,PEX11B,PEX14,PFKL,PKD2,PKD2L1,PKM,PLN,PNPT1,POLQ,PPP5C,PRKAA1,PRKAB1,PRKCZ,RAD51,RAD52,RASEF,RASGRP1,RCC1,RIPK1,RIPK3,RNF213,RS1,RXRA,RXRG,RYR1,RYR3,S100A10,SAMHD1,SCARA5,SCUBE1,SEMG1,SEMG2,SEPT11,SEPT4,SEPT7,SEPT9,SH3GLB1,SHARPIN,SHKBP1,SHMT1,SHMT2,SIGMAR1,SKI,SLC1A1,SLC1A2,SLC22A1,SLC22A6,SLC26A5,SLC34A1,SLC6A4,SLC9A1,SMAD4,SMARCAD1,SNX2,SOD2,SPAG9,SPAST,SPTBN5,SQSTM1,SRR,STOM,SYT1,SYT11,TCL1A,TDO2,TEK,TGM2,TGM3,THG1L,TK1,TMCC1,TMED10,TMEM120A,TNFAIP1,TNFAIP3,TNFRSF9,TNFSF11,TNNT2,TOR1A,TOR1B,TOR2A,TP53,TP63,TP73,TRA2B,TRADD,TRAF2,TRAPPC10,TRAPPC11,TRAPPC12,TRIM21,TRIM22,TRIM28,TRIM34,TRIM6,TRIM72,TRMT61B,TRPA1,TRPM1,TRPM3,TRPM6,TRPM7,TRPM8,TRPS1,TRPV1,TRPV5,TYSND1,USP16,UXS1,VASP,VCP,VWA2,VWF,WIZ,XRCC6,YME1L1,YWHAB,ZBTB1,ZC3H12A,ZNHIT6	TetrapodAncestor	104.245
GO.Biological.Process	GO:0002685	regulation.of.leukocyte.migration	313	5.961940e-109	7.701038e-105	2.460395e-107	1.353446e+0	ABR,ADA,ADAM8,ADORA1,AIF1,ANO6,ANXA1,APOD,APP,BCR,BDKRB1,BMP5,BST1,C1QBP,C3AR1,C5,CALR,CAMK1D,CCL1,CCL19,CCL2,CCL21,CCL28,CCL3,CCL4,CCL5,CCL7,CCL8,CCR1,CCR2,CCR6,CCR7,CD300A,CD74,CMKLR1,CREB3,CSF1,CXCL1,CXCL10,CXCL11,CXCL13,CXCL14,CXCL2,CXCL3,CXCL5,CXCL6,CXCL8,CXCL9,CXCR3,CYP19A1,DAPK2,DDT,DOCK8,EDN1,EDN2,EDN3,F2RL1,F7,FADD,GAS6,GPR18,GPSM3,GREM1,HMGB1,HMOX1,IL12A,IL1A,IL1R1,IL23A,IL33,IL4,IL6,IL6R,ITGA2,ITGA2B,ITGA4,JAM3,KARS,KITLG,KLRK1,LBP,LGALS3,LGALS9,LRCH1,LYN,MADCAM1,MAPK14,MAPK3,MIA3,MIF,MMP14,MMP28,MOSPD2,MPP1,MSN,NBL1,NCKAP1L,NOV,PADI2,PDGFD,PF4,PF4V1,PLA2G7,PLCB1,PLVAP,PPBP,PTAFR,PTGER4,PTK2B,PYCARD,RAC1,RAC2,RARRES2,RIPK3,RIPOR2,S100A14,S100A7,SELENOK,SELP,SLC8B1,SLIT2,STAP1,TGFB1,THBS1,THBS4,THY1,TIRAP,TNF,TNFRSF14,TNFRSF18,TNFSF14,TNFSF18,VEGFA,VEGFB,VEGFC,VEGFD,WNT5A,XCL1,ZNF580,ZP3	TetrapodAncestor	104.113
GO.Biological.Process	GO:0022412	cellular.process.involved.in.reproduction.in.multicellular.organism	314	6.274748e-109	8.105092e-105	2.581239e-107	1.250771e+0	ABHD2,ADAD1,ADAM2,AMH,ANGPT2,ARRB1,ARRB2,ASPM,ATM,AURKC,BAX,BBS4,BCL2,BCL2L1,BMP4,BMPR1B,BRIP1,CABYR,CAPZA3,CATSPER1,CATSPER4,CATSPERB,CATSPERD,CATSPERZ,CCDC136,CCDC155,CCDC42,CCNB1,CCNB1IP1,CCR6,CD9,CDC25B,CDYL,CELF1,CELF4,CEP57,CFAP157,CFTR,CHD5,CIB1,CRISP1,CTNNB1,CXADR,DAZL,DDX25,DEAF1,DIAPH2,DLD,DMC1,DMRT1,DNAH1,DND1,DPY19L2,EQTN,ERCC1,EREG,ETV5,ETV6,FABP9,FANCC,FANCG,FBXO5,FMN2,FNDC3A,FOSL1,FOXC1,FSCN3,FSHB,FSHR,FZD4,GALNTL5,GPR149,H3F3A,HMGB2,HOOK1,HSPA2,ICA1L,IHH,ING2,INHBA,INHBB,INSL6,IQCF1,ITGB1,IZUMO1R,JAM3,KDM3A,KLHL32,KMT2B,KNL1,LGR5,LHCGR,LIN28A,LYZL6,MARF1,MAST2,MEI1,MEI4,MEIOC,MKKS,MLH1,MOV10L1,MSH2,MTOR,NANOS3,NECTIN2,NECTIN3,NEURL1,NME5,NOBOX,NPHP1,NPM2,NSUN2,NUP210L,OCA2,ODF2,OSBP2,PABPC1L,PACRG,PAFAH1B1,PANK2,PAQR5,PAQR7,PAQR8,PCSK4,PDE3A,PDILT,PIWIL2,PLA2G3,PLD6,PLPP1,PLPP3,POMZP3,PRDM1,PRKACA,PRM2,PRSS42,PTCHD3,PTK2B,PYGO2,QKI,RARA,REC8,RFX2,RHBDD1,RNF17,RNF2,RNF8,ROBO2,ROPN1,ROPN1L,RPS6,RSPH1,RXFP2,SEPT4,SERPINA5,SFRP1,SIX5,SLC26A3,SLC26A8,SLIRP,SLIT2,SLIT3,SMAD5,SMARCA2,SOHLH1,SOS1,SPACA1,SPACA3,SPAG16,SPAG6,SPAM1,SPANXB1,SPATA46,SPESP1,SPINK1,SPO11,SRC,SRPK1,STRA8,STRBP,SYCP1,TAF4B,TARBP2,TBC1D20,TBPL1,TDRD5,TGFB1,TGFBR1,TIAL1,TNP1,TNP2,TOPAZ1,TPGS1,TRIP13,TSSK1B,TSSK2,TTC26,TTLL1,TXNDC8,UBE2J1,WASHC5,WNT4,YTHDF2,ZBTB16,ZMIZ1,ZMYND15,ZNF830,ZP3,ZPBP2	TetrapodAncestor	104.091
GO.Biological.Process	GO:0071375	cellular.response.to.peptide.hormone.stimulus	315	6.572555e-109	8.489769e-105	2.695165e-107	1.262503e+0	ADCY2,ADCY3,ADCY4,ADCY5,ADCY8,ADIPOQ,AGT,AGTR1,AGTR2,AGTRAP,AHCYL1,AKT2,AP3S1,APC,APEX1,APOBEC1,APPL1,ARG1,ARID1B,ATP6AP1,ATP6V0A4,ATP6V0B,ATP6V0C,ATP6V0D1,ATP6V0D2,ATP6V0E1,ATP6V0E2,ATP6V1B1,ATP6V1B2,ATP6V1C1,ATP6V1C2,ATP6V1D,ATP6V1E1,ATP6V1E2,ATP6V1G1,ATP6V1G3,ATP6V1H,BAIAP2L2,BCAR1,BRIP1,C2CD5,CA2,CAMK2A,CAPN10,CAV1,CAV2,CCL2,CCNA2,CDC5L,CDC6,CDK4,CFLAR,CPEB1,CPEB2,CPS1,CREB1,CRHBP,CRHR1,CRHR2,CRK,CSH1,CSK,CYBA,CYFIP1,DENND4C,EDN1,EEF2K,EIF4EBP1,ENPP1,ENSG00000278139,ERRFI1,FER,FGF21,FOXC2,FOXO1,FOXO4,GAB1,GCGR,GCK,GH1,GH2,GHR,GHRHR,GHSR,GLP1R,GLP2R,GNB2,GNG10,GNG11,GNG12,GNG13,GNG2,GNG3,GNG7,GNG8,GNRHR,GOT1,GPER1,GPLD1,GRB2,GSK3A,GSTP1,HDAC5,HDAC9,HSF1,IDE,IGF1R,IGF2,IL6,INHBB,INPP5K,INS,IRS1,IRS2,IRS4,JAK2,JAK3,KAT2B,KL,LPIN1,LYN,MAPK1,MAPK3,MAS1,MAX,MDM2,MEN1,MGARP,NDEL1,NFKB1,NKX6-1,NR4A1,NR4A2,NR4A3,PAK1,PARP1,PCK1,PDK2,PDPK1,PHIP,PIK3C2A,PIK3CA,PIK3R1,PIK3R2,PIK3R3,PKLR,PKM,PLA2G1B,POR,PPARG,PRKACA,PRKACG,PRKAR1A,PRKAR1B,PRKAR2B,PRKCD,PRKCI,PRKCZ,PRKDC,PRL,PRLR,PTEN,PTK2,PTPN1,PTPRA,PXN,RAB13,RAB31,RAB8A,RAP1B,RELA,RHOQ,RPE65,SH2B2,SHC1,SLC25A33,SLC2A8,SLC30A10,SLC9A1,SMARCC1,SOCS2,SOCS7,SOGA1,SORBS1,SOS1,SP1,SRC,SRD5A1,SREBF1,SRSF5,STAR,STXBP4,TBC1D4,TCIRG1,TGFB1,TRIB3,TSHR,TUSC5,UCP2,UMODL1,USF1,VAMP2,WDTC1,WNT1,XBP1,YWHAG,ZFP36L1,ZNF106	TetrapodAncestor	104.071
GO.Biological.Process	GO:0032835	glomerulus.development	316	1.041910e-108	1.345835e-104	4.258972e-107	1.443316e+0	ACTA2,ANGPT1,ANGPT2,AQP1,BASP1,BCL2,BMP4,CD24,CD34,COL4A3,COL4A4,EGR1,ENPEP,FOXC1,FOXC2,FOXJ1,GPR4,HES1,HEYL,IQGAP1,JAG1,KIRREL3,KLF15,LGR4,LHX1,MAGI2,MEF2C,MPV17,MTSS1,MYO1E,NOTCH1,NOTCH3,NPHS1,NPHS2,OSR1,PDGFB,PDGFRB,PECAM1,PLCE1,PODXL,PROM1,PTPRO,SULF2,TCF21,TEK,VANGL2,WWTR1	TetrapodAncestor	103.871
GO.Biological.Process	GO:0044057	regulation.of.system.process	317	1.079175e-108	1.393970e-104	4.397383e-107	1.155231e+0	ABAT,ABCB4,ABCC8,ABCC9,ACE,ACE2,ACPP,ADA,ADIPOQ,ADORA1,ADORA2A,ADORA2B,ADORA3,ADRA1A,ADRA1B,ADRA1D,ADRA2A,ADRA2B,ADRA2C,ADRB2,AGT,AGTR1,AGTR2,AHCYL1,AIF1,AKAP13,AKAP6,ANK2,ANXA6,APLN,APOA1,APOA2,APOA4,APOA5,AQP1,ARHGAP42,ASIC2,ASPH,ATP1A1,ATP1A2,ATP1A4,ATP1B1,ATP1B2,ATP1B3,ATP2A1,ATP2B1,ATP2B2,ATP2B3,ATP2B4,AVP,AVPR1A,AVPR1B,AVPR2,BDKRB2,BMP10,BMP6,BMPR2,C1QTNF1,C1QTNF3,CACNA1C,CACNA1D,CACNA1F,CACNA1G,CACNA1H,CACNA1S,CACNA2D1,CACNA2D2,CACNA2D3,CACNB1,CACNB2,CACNB4,CACNG2,CACNG3,CACNG5,CACNG6,CACNG7,CACNG8,CALCRL,CALM1,CALM2,CALM3,CAMK2B,CAMK2D,CAMK2G,CARTPT,CASQ1,CASQ2,CASR,CAV1,CAV3,CCK,CCL3,CD38,CDK9,CELF2,CHGA,CHRM1,CHRM2,CHRM3,CHRNA3,CHRNB4,CNN1,CORIN,CRHBP,CRHR1,CRY1,CSRP3,CTDP1,CTGF,CTNNA3,CTTN,CXADR,CYBA,CYP2J2,DAPK3,DBH,DCANP1,DES,DLG1,DMD,DMPK,DOCK4,DOCK5,DRD2,DRD3,DSC2,DSG2,DSP,EDN1,EDN2,EDN3,EDNRB,EGFR,EHD3,EIF2AK3,EMP2,ENSG00000240045,EPAS1,ERRFI1,F2R,F2RL1,FAM19A4,FBXO32,FGF10,FGF12,FGF13,FGFR1,FGG,FKBP1B,FLNA,FMR1,FOXN4,FOXO1,FPGT-TNNI3K,FXYD1,FXYD2,FXYD3,FXYD6,FXYD7,G6PD,GAA,GAL,GAS6,GATA4,GBA,GCH1,GHSR,GJA1,GJC1,GLP1R,GLRA1,GLRX3,GNAO1,GNAS,GPD1L,GPER1,GPR35,GRIN2A,GRIN2D,GRK2,GSK3A,GSTM2,GTF2I,GTF2IRD1,GUCY1A3,HAMP,HAND2,HBEGF,HCN4,HDAC4,HEY2,HGF,HIP1R,HRC,HRH2,HSPB6,HSPB7,HTR2A,HTR2C,IFNG,IGF1,IGFBP5,IL10,IL1B,IL2,IL6,IL6ST,INHA,INHBA,INHBB,INPP5K,ISX,ITGA2,ITPR1,ITPR2,ITPR3,JAK2,JARID2,JUP,KCNA1,KCNA5,KCNB2,KCND1,KCND2,KCNE1,KCNE2,KCNE3,KCNE5,KCNG2,KCNH2,KCNH6,KCNIP1,KCNIP3,KCNIP4,KCNJ11,KCNJ12,KCNJ14,KCNJ2,KCNJ3,KCNJ4,KCNJ5,KCNK1,KCNK15,KCNK3,KCNMB2,KCNMB4,KCNN2,KCNQ1,KISS1,KLF4,LEP,LMCD1,LMNA,MAG,MC3R,MDM2,MECP2,MEF2A,MGLL,MLIP,MSTN,MTG2,MTMR2,MTMR4,MTOR,MTPN,MYBPC3,MYBPH,MYH6,MYH7,MYL3,MYL5,MYL9,MYLK2,MYOCD,MYOG,MYRF,NCMAP,NEUROD1,NEUROG1,NKX2-5,NKX3-1,NLGN1,NLGN3,NMUR2,NOL3,NOS1,NOS1AP,NOS3,NOV,NPFF,NPHS1,NPPC,NPR1,NPR2,NPVF,NPY2R,NR1H2,NR1H3,NR4A3,NRG1,NTSR1,NUP155,OPRD1,OPRK1,OPRL1,OPRM1,OR51E2,OXT,OXTR,P2RX3,P2RX4,PAK1,PARD3,PARP1,PDE4B,PDE4D,PDE5A,PDE9A,PDGFB,PER2,PHOX2B,PIK3CG,PIN1,PKP2,PLCE1,PLN,POMC,POPDC2,PPARGC1A,PPP1R12B,PPP3CA,PRKACA,PRKCA,PRKG1,PROK2,PTAFR,PTEN,PTGER3,PTPN11,PTPRO,RAB11FIP1,RAB11FIP5,RAB8B,REN,RETN,RGS2,RNF10,RNF207,RNLS,RYR1,RYR2,RYR3,S100A1,S100B,SCN1B,SCN2B,SCN3B,SCN4B,SCN5A,SCT,SEMA3A,SGK1,SLC1A1,SLC22A5,SLC8A1,SLC8A2,SLC8A3,SLC9A1,SLC9A3R1,SLN,SMAD4,SMAD7,SMTNL1,SNTA1,SOD1,SOX10,SPHK1,SPX,SREBF1,SRF,SRI,SSTR2,STC1,STIM1,SUMO1,TAC1,TAC4,TACR3,TBX2,TBXA2R,TENM4,TGFB2,TH,THRA,THRB,TIFAB,TLX3,TMEM100,TMEM65,TMIGD3,TNFRSF21,TNNC1,TNNC2,TNNI2,TNNI3,TNNI3K,TNNT1,TNNT2,TNNT3,TNR,TRDN,TRIM63,TRPC1,TRPC3,TRPM4,TRPV1,TWF1,TYMP,UCN,UTRN,UTS2,UTS2R,WNK1,WNK3,WNK4,YWHAE,ZC3H12A	TetrapodAncestor	103.856
GO.Biological.Process	GO:0010464	regulation.of.mesenchymal.cell.proliferation	318	4.007893e-108	5.176995e-104	1.627986e-106	1.441909e+0	BMP4,BMPR1A,CHRD,CTNNB1,FGF9,FGFR1,FGFR2,FOXF1,FOXP2,IHH,IRS2,LMNA,LRP5,MYC,MYCN,NFIB,PDGFA,PHF14,PRRX1,PTN,SHOX2,SMO,SOX9,STAT1,TBX1,TGFBR2,TP63,VEGFA,WNT11,WNT5A,ZEB1	TetrapodAncestor	103.286
GO.Biological.Process	GO:0030098	lymphocyte.differentiation	319	2.331690e-107	3.011844e-103	9.441517e-106	1.259698e+0	ABL1,ADA,ADGRG3,AICDA,ANXA1,ATG5,ATM,ATP11C,AXL,BAK1,BAX,BCL11B,BCL2,BCL3,BCL6,BLNK,BMX,BRAF,BTK,CARD11,CBFB,CCR6,CCR7,CCR9,CD1D,CD28,CD3D,CD3E,CD74,CD79B,CD8A,CDK6,CEBPG,CHD7,CLCF1,CLEC4D,CLEC4E,CMTM7,CR2,CTNNB1,DCAF1,DCLRE1C,DLL1,DLL4,DNAJA3,DOCK10,DOCK11,DOCK2,EGR1,EOMES,EP300,FADD,FAS,FCER1G,FLT3LG,FOXN1,FOXP3,FUT7,FZD5,FZD7,FZD8,FZD9,GATA3,GLI3,GON4L,GPR18,GPR183,HDAC4,HDAC5,HDAC9,HHEX,HMGB1,HNF1A,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNB1,IFNE,IFNG,IFNK,IFNW1,IKZF1,IL10,IL12B,IL15,IL18R1,IL2,IL4,IL6,IL7,IL7R,IRF1,IRF4,ITFG2,ITGA4,ITGB1,ITK,ITM2A,ITPKB,JAG2,JAK3,JMJD6,KDELR1,KLF6,LCK,LEF1,LEP,LEPR,LFNG,LGALS1,LIG4,LRRC8A,LY6D,LYL1,MAFB,MALT1,MERTK,MFNG,MSH2,NFAM1,NHEJ1,NKX2-3,NOTCH2,NTRK1,ONECUT1,PATZ1,PIK3CD,PIK3R1,PKNOX1,PLA2G2D,PLCG2,PLCL2,POLM,POU1F1,POU2F2,PPP3CB,PREX1,PRKDC,PSMB11,PTGER4,PTK2B,PTPN22,RAG1,RAG2,RBPJ,RC3H1,RC3H2,RELB,RIPK3,RORC,RPS6,RSAD2,RUNX2,SATB1,SEMA4A,SLAMF6,SOX4,SPI1,SPN,SRF,STAT6,SYK,TCF3,TGFB1,THEMIS,TNFSF8,TPD52,TYRO3,VAV1,VCAM1,WNT1,WNT4,ZAP70,ZBTB1,ZFP36L1,ZFP36L2,ZFPM1,ZNF683	TetrapodAncestor	102.521
GO.Biological.Process	GO:0060541	respiratory.system.development	320	5.790171e-107	7.479164e-103	2.337239e-105	1.233317e+0	AARD,ABCA12,ACVR2B,ADA,ADAMTS2,ADAMTSL2,AGR2,ALDH1A3,ARG1,ASCL1,ASXL1,ATXN1L,BAG6,BASP1,BMP4,BMPR1A,BMPR2,CCBE1,CCDC40,CEBPA,CELSR1,CHD7,CHI3L1,CREB1,CRISPLD2,CTGF,CTNNB1,CTSH,CTSZ,CYP1A2,DHCR7,DISP1,DLG5,DLX5,DNAAF1,DPPA2,DPPA4,EDA,EDN2,EGFR,EIF4E,EIF4EBP1,EP300,EPAS1,ERRFI1,ESRP2,EYA1,FGF1,FGF10,FGF18,FGF7,FGF9,FGFR1,FGFR2,FGFRL1,FLT4,FOXA1,FOXF1,FOXJ1,FOXP2,FSTL3,GATA6,GLI2,GLI3,GNG8,GPC3,GRHL2,HEG1,HES1,HESX1,HHEX,HIKESHI,HMGB1,HS6ST1,HSD11B1,HSPB11,HYDIN,ID1,IGFBP5,ITGA3,JMJD6,KCNAB1,KLF2,KRAS,LAMA5,LEF1,LIF,LIPA,LOX,LOXL3,LRP6,MAN1A2,MAN2A1,MAPK1,MAPK3,MMP14,MSC,MYCN,MYOCD,NFIB,NOG,NOS3,NOTCH1,NPHP3,NUMB,PDGFA,PDGFRB,PDPN,PGR,PHEX,PHF14,PHOX2B,PITX2,PKD1,PKDCC,PROX1,PTK7,PTN,RARA,RARG,RBP4,RBPJ,RC3H2,RDH10,RSPO2,SEC24B,SIM2,SKI,SLC23A1,SMAD2,SMCHD1,SOX11,SOX9,SPRY1,SPRY2,SREBF1,SRF,STRA6,TAB1,TBX5,TCF21,TGFBR2,THRA,THRB,TIMELESS,TNC,TNS3,TULP3,VANGL2,VEGFA,WNT11,WNT5A,WNT7B,ZFPM2,ZIC3	TetrapodAncestor	102.126
GO.Biological.Process	GO:1903530	regulation.of.secretion.by.cell	321	7.555780e-107	9.759801e-103	3.040436e-105	1.146679e+0	AACS,ABAT,ABCC8,ABL1,ABR,ACHE,ADAM8,ADAM9,ADCY5,ADCYAP1,ADGRE2,ADIPOQ,ADORA1,ADORA2A,ADORA2B,ADRA2A,ADRA2B,ADRA2C,AGT,AGTR1,AGTR2,ALOX15B,ANGPT1,ANKRD1,ANO1,ANXA1,ANXA4,AP1G1,APLN,APOA1,APOA2,ARF1,ARFIP1,ARG2,ARHGEF7,ARL2,ARL2BP,ARNTL,ARRB1,ASIC1,ATG5,ATP13A2,ATP6AP1,AVP,AVPR1A,BAD,BANK1,BCR,BLK,BMP6,BMP8A,BRAF,BRSK2,C12orf4,C1QTNF1,C1QTNF12,C1QTNF3,C2CD2L,C5,CACNA1A,CACNA1C,CACNA1D,CACNA1E,CACNA1G,CACNA1H,CACNA1I,CACNA2D2,CADM1,CADPS2,CAMK2A,CAPN10,CARD16,CARD17,CARD18,CARTPT,CASP1,CASP5,CASR,CCK,CCKAR,CCL19,CCL3,CCL5,CCR2,CCR7,CD14,CD2,CD274,CD300A,CD34,CD38,CD40,CD58,CDK16,CDK5,CDK5R2,CFTR,CHD7,CHGA,CHIA,CHMP2A,CHRNA3,CHRNA6,CHRNB2,CHRNB4,CHUK,CIDEA,CLASP1,CLASP2,CLEC4E,CLEC6A,CLEC9A,CNR1,CPB2,CPLX1,CPLX2,CPLX3,CPLX4,CPT1A,CREB1,CRHBP,CRHR1,CRTAM,CRY1,CSF1R,DDX58,DHX9,DISP1,DNAJC1,DNM1L,DOC2A,DOC2B,DPH3,DRD2,DRD3,DRD4,DTNBP1,EDN1,EDN3,EFNA5,EGFR,ENSG00000173366,EPHA5,ERP29,EXPH5,EZR,F2R,F2RL1,FAM3D,FCER1G,FCN1,FER,FERMT1,FES,FFAR1,FFAR2,FFAR3,FFAR4,FGF20,FGF23,FGFR1,FGG,FGR,FKBP1B,FMR1,FN1,FOXA2,FOXF1,FOXP3,GAB2,GAL,GAPDH,GAS6,GATA2,GATA3,GCK,GDNF,GHRH,GHRHR,GHSR,GIP,GIPR,GJA1,GLP1R,GLUD1,GLUL,GNAS,GOLPH3,GPAM,GPER1,GPLD1,GPR68,GRIK5,GRK2,GRM7,GRP,GSDMD,HAP1,HAVCR2,HGS,HIF1A,HMGB1,HMGCR,HMGN3,HMHB1,HMOX1,HNF4A,HRH3,HTR1A,HTR1B,HTR2A,HTR2B,HTR2C,ICA1,IDH2,IFNA2,IFNAR1,IFNG,IGF1,IL10,IL13,IL13RA2,IL17A,IL17F,IL17RA,IL17RB,IL17RC,IL1A,IL1B,IL1R2,IL1RAP,IL1RAPL1,IL1RL1,IL2,IL26,IL33,IL36RN,IL4,IL5,IL6,INHA,INHBA,INHBB,INS,IRF3,IRS1,IRS2,ISL1,ITGAM,ITGB2,ITPR1,ITPR2,ITPR3,JAGN1,JAK2,KALRN,KARS,KCNA2,KCNA5,KCNB1,KCNC2,KCNG2,KCNJ11,KCNMB4,KCNS3,KIF5B,KISS1,KRT20,LEP,LGALS9,LGI3,LGR4,LIF,LLGL2,LPL,LRP5,LRRC32,LRRK2,LYN,MAOB,MAP4K4,MAPK11,MAPK14,MAPK3,MARCKS,MCTP1,MCU,MEF2C,MICAL1,MIF,MMP12,MPC2,MTNR1B,MYO18A,MYRIP,NAPA,NCS1,NDUFAF2,NEUROD1,NF1,NKX3-1,NKX6-1,NLGN1,NLRP1,NLRP10,NLRP2,NLRP7,NNAT,NOS2,NOTCH1,NOV,NPFF,NPVF,NPY2R,NPY5R,NR0B2,NR1D1,NR1H2,NR1H3,NR1H4,NRXN1,NSF,NTSR1,OPRK1,OPRM1,OR51E2,OR56A1,OR56A4,OR5T3,ORM1,ORM2,OSM,OXCT1,OXT,OXTR,P2RX7,P2RY1,P3H1,PAEP,PAM,PANX1,PASK,PAX8,PCK2,PCLO,PDCD6IP,PDE8B,PDPK1,PER2,PFKFB2,PFKL,PFN2,PHPT1,PIK3C3,PIM3,PINK1,PLA2G1B,PLA2G6,PML,PNKD,POMC,PPARD,PPP3CA,PPP3CB,PRAM1,PRKCA,PRKCE,PRKCZ,PRKN,PSMD9,PTAFR,PTGER4,PTPN11,PTPN22,PTPN23,PYCARD,PYDC1,PYDC2,RAB11FIP1,RAB11FIP5,RAB15,RAB21,RAB26,RAB27A,RAB27B,RAB2B,RAB33B,RAB37,RAB3B,RAB3C,RAB3D,RAB3GAP1,RAB5A,RAB7A,RAB8A,RAB8B,RAC2,RALA,RALB,RAP1A,RAP1B,RAPGEF3,RASGRP1,RASL10B,RBP4,REN,REST,RETN,RFX3,RFX6,RGCC,RHBDD3,RHBDF1,RHBDF2,RIMS1,RIMS3,RIMS4,RIPK2,RPH3A,RPH3AL,RSAD2,RSG1,SAA1,SCAMP5,SCG5,SCT,SDC4,SDCBP,SELENOK,SELENOT,SEPT5,SERGEF,SERP1,SFRP1,SIDT2,SIRT3,SIRT4,SLC16A1,SLC25A5,SLC25A6,SLC2A1,SLC2A2,SLC30A1,SLC30A8,SLC6A4,SLC8B1,SLC9B2,SMAD4,SMPD3,SNAP25,SNCA,SNCAIP,SNCG,SNF8,SNX4,SOCS1,SOX11,SOX4,SRC,SRCIN1,SREBF1,SRI,SSC5D,SSTR5,STAM,STX1A,STX1B,STX4,STXBP1,STXBP2,STXBP4,STXBP5,STXBP5L,STXBP6,STYK1,SYBU,SYK,SYN1,SYT1,SYT10,SYT11,SYT13,SYT15,SYT17,SYT2,SYT4,SYT5,SYT6,SYT7,SYT8,SYT9,SYTL1,SYTL3,SYTL4,SYTL5,TAC1,TARDBP,TFAP2B,TFR2,TGFB1,TGFB2,TIAM1,TLR1,TLR10,TLR2,TLR4,TLR5,TLR6,TLR9,TM7SF3,TMBIM6,TMEM27,TNF,TNFRSF14,TNFRSF21,TNFRSF4,TNFRSF9,TNFSF11,TRAF2,TRAF6,TRIM6,TRIM9,TRPM4,TRPV6,TSG101,TTN,TWIST1,UCN,UCN3,UCP2,UNC13A,UNC13B,UQCC2,UTS2,VAMP2,VAMP3,VAMP8,VEGFC,VPS35,VPS4A,VPS4B,VSNL1,VTCN1,WLS,WNT5A,XBP1,ZC3H12A,ZP3	TetrapodAncestor	102.011
GO.Biological.Process	GO:0006082	organic.acid.metabolic.process	322	8.348920e-107	1.078430e-102	3.349161e-105	1.137654e+0	AACS,AADAT,AARS,AARS2,AARSD1,AASDHPPT,AASS,ABAT,ABCC2,ABCD1,ABCD2,ABCD3,ABCG2,ABHD10,ABHD14A-ACY1,ABHD14B,ABHD5,ACAA2,ACACA,ACACB,ACAD10,ACAD8,ACAD9,ACADL,ACADM,ACADS,ACADVL,ACAN,ACAT1,ACAT2,ACBD5,ACMSD,ACO1,ACOT1,ACOT11,ACOT12,ACOT2,ACOT4,ACOT6,ACOT7,ACOT8,ACOX2,ACOX3,ACOXL,ACSBG1,ACSBG2,ACSF2,ACSL1,ACSL3,ACSL4,ACSL5,ACSM1,ACSM2A,ACSM2B,ACSM3,ACSM4,ACSM5,ACSM6,ACSS1,ACSS2,ACY1,ADH7,ADI1,ADIPOQ,ADIPOR1,ADIPOR2,ADO,ADPGK,ADSS,ADSSL1,AFMID,AGMAT,AGXT,AGXT2,AHCY,AHCYL1,AHCYL2,AKR1A1,AKR1D1,ALDH1A3,ALDH1L1,ALDH1L2,ALDH3A2,ALDH4A1,ALDH5A1,ALDH6A1,ALDH7A1,ALDH8A1,ALDOA,ALDOB,ALKBH7,ALOX15,ALOX15B,ALOX5,ALOX5AP,AMACR,AMDHD2,ANGPT1,APIP,ARG1,ARG2,ART4,ARV1,ASL,ASNS,ASNSD1,ASPA,ASPG,ASS1,ATF4,ATIC,ATP8B1,AUH,AWAT1,AZIN1,AZIN2,B3GALT6,B3GAT1,B3GAT2,B3GAT3,B3GNT2,B3GNT3,B3GNT7,B4GALT1,B4GALT2,B4GALT3,B4GALT4,B4GALT5,B4GALT6,BAAT,BCAN,BCAT1,BCAT2,BCKDHA,BCKDHB,BCKDK,BCO2,BDH2,BGN,BLMH,BPGM,BPHL,BPNT1,BRCA1,BSG,BTD,C14orf159,C3,CARMIL1,CARNMT1,CARNS1,CARS,CBR1,CBR4,CBS,CCDC12,CD74,CDO1,CEL,CES1,CES2,CH25H,CHST1,CHST11,CHST12,CHST14,CHST2,CHST3,CHST4,CHST5,CHST6,CHST7,CHST9,CHSY3,CKMT1A,CKMT1B,CKMT2,CLN3,CMAS,CPS1,CPT1A,CPT1B,CPT1C,CPT2,CRABP1,CRABP2,CRAT,CROT,CRTAP,CRYM,CS,CSAD,CSGALNACT1,CSGALNACT2,CSPG4,CTH,CTNS,CTPS1,CTPS2,CYB5A,CYB5R3,CYGB,CYP1A1,CYP1A2,CYP1B1,CYP26A1,CYP26B1,CYP26C1,CYP27A1,CYP27C1,CYP2A13,CYP2A6,CYP2A7,CYP2B6,CYP2C18,CYP2C19,CYP2C8,CYP2C9,CYP2D6,CYP2F1,CYP2J2,CYP2S1,CYP2W1,CYP39A1,CYP46A1,CYP4A11,CYP4F22,CYP4F8,CYP4V2,CYP7A1,CYP8B1,CYTL1,D2HGDH,DAGLA,DAGLB,DARS,DARS2,DBT,DCN,DCT,DCXR,DDAH1,DDC,DDO,DECR1,DEGS1,DHFR,DHFR2,DHTKD1,DLAT,DLD,DPEP1,DPYD,DSE,DSEL,EARS2,ECH1,ECHDC1,ECHDC2,ECHS1,ECI1,ECI2,EDN1,EDN2,EGFLAM,EGLN1,EGLN2,EGLN3,EHHADH,ELOVL1,ELOVL2,ELOVL3,ELOVL4,ELOVL6,ELOVL7,ENO3,ENO4,ENOSF1,ENPP1,ENSG00000249319,ENSG00000255730,ENSG00000255835,ENSG00000256591,ENSG00000260300,ENSG00000260643,ENSG00000269547,ENSG00000276490,ENSG00000284512,EPHX2,EPRS,ERO1A,ERO1B,ETFA,ETFB,EXT1,EXT2,EXTL2,EXTL3,FA2H,FAAH,FABP3,FADS1,FADS2,FADS3,FADS6,FAH,FAM213B,FARS2,FARSA,FASN,FDXACB1,FH,FMOD,FN3K,FOLH1,FPGS,FTCD,G6PC,GADL1,GAPDH,GAPDHS,GARS,GART,GATB,GATC,GBA2,GCAT,GCDH,GCH1,GCK,GCKR,GCLM,GCSH,GFPT1,GFPT2,GGH,GGT1,GGT2,GGT5,GGT7,GGTLC2,GGTLC3,GHR,GLB1,GLCE,GLDC,GLO1,GLUD1,GLUD2,GLUL,GLYAT,GLYATL1,GLYATL2,GMPS,GNE,GNMT,GNS,GOT1,GOT1L1,GOT2,GPAM,GPAT4,GPC1,GPT,GPT2,GRHPR,GSS,GSTA1,GSTM2,GSTO2,GSTP1,GSTZ1,HAAO,HACD1,HACD2,HACD3,HACD4,HACL1,HADHA,HADHB,HAO1,HAO2,HARS,HARS2,HDC,HEXA,HGD,HIBCH,HIF1A,HK3,HLCS,HMGCL,HNF4A,HNMT,HOGA1,HPD,HPGD,HPGDS,HPSE,HS3ST3B1,HS3ST4,HS3ST5,HS6ST1,HS6ST2,HS6ST3,HSD17B12,HSD17B4,HSD17B8,HSD3B7,HTD2,HYKK,IARS,IARS2,IDH2,IDH3A,IDH3G,IDNK,IDO1,IDO2,IDS,IDUA,IGF1,IL4I1,IMPAD1,IVD,IYD,KARS,KERA,KMO,KYAT1,KYNU,LARS,LARS2,LDHA,LDHAL6A,LDHAL6B,LDHB,LDHC,LEP,LGSN,LIPE,LIPF,LPIN1,LPIN3,LPL,LPO,LRAT,LTC4S,LUM,LYPLA1,LYPLA2,MAPK14,MAPK3,MAPKAPK2,MARC1,MARC2,MARS2,MCAT,MCCC1,MCCC2,MCEE,MDH1B,MDH2,ME1,ME2,ME3,MECP2,MECR,MGLL,MGST2,MGST3,MIF,MINPP1,MLYCD,MORC2,MPC1,MPC2,MPO,MPST,MRI1,MRS2,MSRA,MTAP,MTHFD1,MTHFD1L,MTHFD2,MTHFD2L,MTHFR,MTHFS,MTRR,MUT,NAALAD2,NAGK,NAGS,NARS,NARS2,NAT8L,NDNF,NDST1,NDST2,NDST3,NDST4,NDUFAB1,NFS1,NIT2,NMNAT3,NNT,NOS1,NOS2,NOS3,NOX4,NPC1,NPL,NR1H4,NR4A3,NR5A2,NUDT19,NUDT7,ODC1,OGDH,OGDHL,OGN,OLAH,OMD,OSBP,OSBPL2,OSBPL3,OSBPL9,OTC,OXSM,P4HA1,P4HB,PADI1,PADI2,PADI3,PADI4,PADI6,PAH,PAM,PANK2,PAPSS2,PARK7,PARP9,PARS2,PC,PCBD1,PCCB,PCK1,PCK2,PCYOX1,PCYOX1L,PDHA1,PDHA2,PDHB,PDHX,PDPN,PDXDC1,PDZD11,PECR,PEMT,PEPD,PER2,PEX13,PEX2,PEX7,PFKFB1,PFKFB2,PFKL,PFKP,PGAM1,PGAM2,PGAM4,PGD,PGK1,PGK2,PGM2L1,PHGDH,PHYH,PHYKPL,PKLR,PKM,PLA2G10,PLA2G15,PLA2G1B,PLA2G3,PLA2G4A,PLA2G4B,PLA2G4F,PLA2G5,PLOD2,PLP1,PM20D1,PNKD,PNP,PNPLA3,PODXL2,POLG2,POR,PPARA,PPARD,PPARG,PPARGC1A,PRDX4,PRELP,PRG3,PRKAA1,PRKAA2,PRKAB1,PRKAG2,PRKAG3,PRKAR2B,PRODH,PRODH2,PRPS1,PSAT1,PSPH,PTGDS,PTGES,PTGES2,PTGES3L-AARSD1,PTGIS,PTGR1,PTGR2,PTGS1,PTS,PYCR1,PYCR2,PYCR3,QDPR,QKI,QRSL1,RARS,RARS2,RBP1,RDH10,RENBP,RGN,RIMKLA,RIMKLB,SARDH,SARS,SARS2,SCD,SCLY,SCP2,SCPEP1,SDHA,SDHAF2,SDHAF3,SDHB,SDHD,SDHD,SDS,SDSL,SEPHS1,SEPSECS,SERINC3,SERINC5,SESN2,SGPL1,SGSH,SHMT1,SHMT2,SIRT4,SLC16A1,SLC16A8,SLC16A9,SLC17A3,SLC19A1,SLC1A3,SLC22A11,SLC22A12,SLC23A1,SLC23A2,SLC25A17,SLC25A21,SLC26A1,SLC26A2,SLC27A1,SLC27A2,SLC27A3,SLC27A4,SLC27A5,SLC27A6,SLC2A1,SLC2A3,SLC2A9,SLC34A1,SLC35D1,SLC35D2,SLC46A1,SLC5A6,SLC6A14,SLC6A6,SLC6A8,SLC7A4,SLC7A5,SLC7A6,SLC7A7,SLC7A8,SMS,SNCA,SORD,SPOCK2,SPOCK3,SRD5A2,SRR,SSTR4,ST20-MTHFS,ST3GAL1,ST3GAL2,ST3GAL3,ST3GAL4,ST3GAL6,ST6GAL1,STAR,SUCLA2,SUCLG2,SULF2,SULT1A1,SULT1A2,SULT1A4,SULT1C2,SULT1C4,SULT2A1,SULT2B1,SULT4A1,SULT6B1,SUOX,SYK,TARS,TAT,TBXAS1,TDO2,TECR,TECRL,TH,THEM4,THEM5,THNSL2,TLR2,TNFRSF1A,TPH1,TPH2,TPST1,TPST2,TST,TYMS,TYR,TYRP1,UCP3,UEVLD,UGT1A1,UGT1A10,UGT1A3,UGT1A4,UGT1A5,UGT1A6,UGT1A8,UGT1A9,UPB1,UROC1,UST,VANGL2,VCAN,VNN1,VNN2,VNN3,WARS,WARS2,XBP1,XYLT1,XYLT2,YARS,YARS2	TetrapodAncestor	101.967
GO.Biological.Process	GO:0070374	positive.regulation.of.ERK1.and.ERK2.cascade	323	9.156753e-107	1.182778e-102	3.661851e-105	1.281411e+0	ABL1,ACKR3,ADCYAP1,ADRA1A,AGER,ALKAL1,ALOX15,ANGPT1,APP,ARAF,ARHGAP8,ARRB1,ARRB2,ATP6AP1,BMP2,BMP4,BMPER,BRAF,CALCR,CAVIN3,CCL1,CCL11,CCL13,CCL14,CCL15,CCL15-CCL14,CCL16,CCL17,CCL18,CCL19,CCL2,CCL21,CCL22,CCL23,CCL3,CCL3L3,CCL4,CCL4L2,CCL5,CCL7,CCL8,CCR1,CCR7,CD36,CD44,CD74,CFLAR,CHI3L1,CIB1,CSF1R,CTGF,CX3CL1,CYSLTR2,DDT,DNAJC27,DRD2,DSTYK,EGFR,EPO,ERBB4,F2R,F2RL1,FBXW7,FFAR4,FGF1,FGF10,FGF18,FGF19,FGF2,FGF20,FGF21,FGF23,FGF4,FGFR2,FGFR3,FGFR4,FGG,FLT4,FSHR,GAREM1,GAS6,GCNT2,GLIPR2,GPER1,GPNMB,GPR183,GPR55,HAND2,HAVCR2,HCRTR1,HMGB1,HMGCR,HRAS,HTR2A,HTR2B,HTR2C,IL26,IL6,JUN,KARS,LGALS9,MAP2K2,MAPK3,MARCO,MIF,NDRG4,NECAB2,NOD1,NOTCH1,NOTCH2,NOX4,NPTN,NPY5R,NQO2,NRP1,NTRK1,OPRM1,P2RY1,PDE8A,PDGFA,PDGFB,PDGFC,PDGFD,PDGFRB,PHB,PLA2G2A,PLA2G5,PRKCA,PRKCZ,PRKD2,PTEN,PTK2B,PTPN11,PTPN22,PYCARD,RAF1,RAP1A,RAP1B,RAPGEF1,RAPGEF2,RASGRP1,RIPK2,S100A7,SEMA7A,SHC1,SLC30A10,SPRY2,SRC,TEK,TGFB1,THPO,TIRAP,TLR4,TNF,TNFAIP8L3,TNFRSF11A,TNFSF11,TREM2,XCL1,XCL2	TetrapodAncestor	101.927
GO.Biological.Process	GO:0030323	respiratory.tube.development	324	1.536670e-106	1.984917e-102	6.126286e-105	1.241779e+0	AARD,ABCA12,ACVR2B,ADA,ADAMTS2,ADAMTSL2,AGR2,ARG1,ASCL1,ASXL1,ATXN1L,BAG6,BMP4,BMPR1A,BMPR2,CCBE1,CCDC40,CEBPA,CELSR1,CHI3L1,CREB1,CRISPLD2,CTGF,CTNNB1,CTSH,CTSZ,CYP1A2,DHCR7,DLG5,DNAAF1,DPPA2,DPPA4,EDN2,EGFR,EIF4E,EIF4EBP1,EP300,EPAS1,ERRFI1,ESRP2,EYA1,FGF1,FGF10,FGF18,FGF7,FGF9,FGFR1,FGFR2,FLT4,FOXA1,FOXF1,FOXJ1,FOXP2,FSTL3,GATA6,GLI2,GLI3,GPC3,GRHL2,HECA,HEG1,HES1,HHEX,HIKESHI,HMGB1,HS6ST1,HSD11B1,HSPB11,ID1,IGFBP5,ITGA3,JMJD6,KLF2,KRAS,LAMA5,LIF,LIPA,LOX,LOXL3,MAN1A2,MAN2A1,MAPK1,MAPK3,MMP14,MYCN,MYOCD,NFIB,NOG,NOS3,NOTCH1,NPHP3,NUMB,PCSK5,PDGFA,PDGFRB,PDPN,PGR,PHEX,PHF14,PITX2,PKD1,PKDCC,PROX1,PTK7,PTN,RBP4,RBPJ,RC3H2,RDH10,RSPO2,SEC24B,SIM2,SLC23A1,SMAD2,SOX11,SOX9,SPRY1,SPRY2,SREBF1,SRF,STRA6,TAB1,TBX5,TCF21,TGFBR2,THRA,THRB,TIMELESS,TNC,TNS3,TRAF4,TULP3,VANGL2,VEGFA,WNT11,WNT5A,WNT7B,ZFPM2,ZIC3	TetrapodAncestor	101.702
GO.Biological.Process	GO:0007346	regulation.of.mitotic.cell.cycle	325	1.846004e-106	2.384483e-102	7.336872e-105	1.164024e+0	AATF,ABL1,ACTR1A,AFAP1L2,AIF1,ALMS1,ANAPC1,ANAPC11,ANAPC16,ANAPC2,ANAPC4,ANAPC5,ANGEL2,ANKRD17,ANKRD53,ANLN,ANXA1,APC,APEX1,APP,ASCL1,ASNS,ATAD5,ATM,AURKA,AURKAIP1,AURKB,BAX,BCL2,BCL2L1,BCL6,BECN1,BID,BIRC5,BMP4,BMP7,BRCA1,BRD4,BRINP1,BRINP2,BRINP3,BTC,BTG2,BTG3,BTG4,BTRC,BUB1,CARM1,CASP2,CAV2,CCDC8,CCL2,CCNB1,CCNB3,CCND1,CCND2,CCP110,CD28,CDC14A,CDC14B,CDC16,CDC20,CDC23,CDC25B,CDC25C,CDC26,CDC27,CDC42,CDC45,CDC6,CDC73,CDCA5,CDK1,CDK10,CDK13,CDK19,CDK2,CDK2AP2,CDK4,CDK5RAP2,CDK6,CDKN1A,CDKN1B,CDKN1C,CDKN2B,CENPE,CENPF,CENPJ,CEP164,CEP192,CEP250,CEP41,CEP57,CEP63,CEP72,CEP78,CEP85,CEP97,CHEK1,CHEK2,CHFR,CHMP1A,CHMP1B,CHMP2A,CHMP2B,CHMP4B,CHMP4C,CHMP5,CKAP5,CKS1B,CKS2,CLASP1,CLTC,CNOT1,CNOT10,CNOT11,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT8,CNTRL,CRADD,CSNK1D,CSNK1E,CTDSP1,CTDSP2,CTDSPL,CTNNB1,CUL1,CUL3,CUL4A,CUL7,CUL9,CYP1A1,DACT1,DAPK3,DBF4B,DCTN1,DCTN3,DCUN1D3,DDB1,DDX3X,DLG1,DLGAP5,DMRT1,DONSON,DRD3,DUSP1,DUSP3,DYNC1H1,DYNC1LI1,DYNLL1,DYNLT3,E2F1,E2F4,E2F7,E2F8,E4F1,ECD,EDN1,EDN3,EGF,EGFR,EIF4E,EIF4EBP1,EME1,EME2,EP300,EPGN,ERCC2,ERCC3,EREG,ESPL1,EZH2,FANCI,FBXL7,FBXO31,FBXO5,FBXO7,FBXW5,FGF10,FGFR1,FGFR1OP,FOXA1,FOXC1,FOXG1,FOXN3,FOXO4,FZD3,FZR1,GADD45A,GADD45GIP1,GAS1,GBF1,GEN1,GIGYF2,GJC2,GML,GNAI1,GPNMB,GPR132,GTSE1,H2AFY,HAUS2,HAUS3,HAUS4,HAUS6,HAUS7,HAUS8,HECA,HECW2,HES1,HMGA2,HMMR,HNRNPU,HRAS,HSF1,HSPA2,HUS1,HUS1B,ID2,IGF1,IGF2,IK,IL10,IL1A,IL1B,INO80,INS,INTS13,INTS3,JADE1,KANK2,KCNA5,KCNH5,KIF11,KIF20B,KIF25,KLHL22,L3MBTL1,LCMT1,LRP5,LSM11,MAD1L1,MAD2L1,MAD2L1BP,MAD2L2,MAEA,MAGI2,MAP2K2,MAP2K3,MAP2K4,MAP2K6,MAP2K7,MAP3K1,MAP3K14,MAP3K19,MAP3K2,MAP3K3,MAP3K4,MAP3K8,MAP4K1,MAP4K3,MAP4K4,MAP9,MAPRE1,MCIDAS,MCPH1,MDC1,MDM2,MDM4,MECP2,MEIOC,MEIS2,MEPCE,MIIP,MINK1,MRE11,MRNIP,MSH2,MTA3,MTBP,MUC1,MUS81,MYO16,NAA10,NABP1,NAE1,NBN,NDC80,NEDD1,NEK1,NEK11,NEK4,NEK6,NEK7,NEUROG1,NINL,NKX3-1,NLE1,NOP53,NPM1,NPM2,NRK,NSMCE2,NUP62,NUSAP1,ODF2,ORAOV1,OVOL1,PAFAH1B1,PAK1,PAK2,PAK3,PAK4,PAK5,PARP3,PBX1,PCBP4,PCID2,PCM1,PCNA,PCNT,PDGFB,PDGFRB,PDPN,PDXP,PHIP,PHOX2B,PID1,PIDD1,PIM1,PIM2,PIM3,PIN1,PINX1,PKD1,PKD2,PKIA,PKMYT1,PLAGL1,PLCB1,PLK1,PLK2,PLK3,PLK4,PLK5,PML,PNPT1,POLDIP2,PPP1R9B,PRCC,PRKACA,PRKAR2B,PRKCA,PRKDC,PRMT1,PRMT5,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTCH1,PTEN,PTPN11,PTPN3,PTTG1,PTTG2,RAD17,RAD21,RAD51B,RAD51C,RAD9A,RAE1,RANBP2,RANBP3,RANBP3L,RB1,RCC1,RCC2,RDX,RFWD3,RGCC,RGPD4,RINT1,RNASEH2B,RPA2,RPA3,RPL24,RPRM,RPS27A,RPS27L,RPS6,RPTOR,SBK2,SCRIB,SDCBP,SETMAR,SFI1,SFN,SH2B1,SHB,SIK1,SIRT1,SIRT2,SLC9A3R1,SLF1,SLF2,SLFN11,SMARCA4,SMC1A,SMC5,SOX4,SPHK1,SSNA1,STAG1,STAG2,STK24,STK26,STK4,STRADA,STRADB,TACC3,TAL1,TAOK1,TAOK2,TERT,TEX14,TFDP2,TGFB1,THAP1,TICRR,TIMP2,TMEM8B,TMOD3,TNF,TNIK,TNKS,TNKS1BP1,TOM1L1,TOP2A,TOPBP1,TP53,TP63,TP73,TPR,TPRA1,TPX2,TRIAP1,TRIM35,TRIP13,TTC28,TTK,TTL,TUBA1A,TUBB,TUBB4A,TUBB4B,TUNAR,UBC,UBE2C,UBE2D1,UBE2E1,UBE2E2,USP2,USP22,USP47,VPS4A,VPS4B,WNT10B,WNT9A,XPC,YWHAE,YWHAG,ZFP36L1,ZFP36L2,ZFYVE19,ZNF207,ZNF385A,ZNF830,ZW10	TetrapodAncestor	101.623
GO.Biological.Process	GO:1901987	regulation.of.cell.cycle.phase.transition	326	1.992931e-106	2.574269e-102	7.896531e-105	1.218968e+0	ACTR1A,AIF1,ALMS1,ANAPC1,ANAPC11,ANAPC16,ANAPC2,ANAPC4,ANAPC5,ANKRD17,ANLN,ANXA1,APC,APEX1,APP,ATAD5,ATF5,ATM,ATP2B4,AURKA,AURKB,BAX,BCL2,BID,BRCA1,BRD4,BTG2,BTRC,BUB1,C10orf99,C8orf4,CARM1,CASP2,CCL2,CCNB1,CCNB3,CCND1,CCND2,CCP110,CDC14A,CDC14B,CDC16,CDC20,CDC23,CDC25A,CDC25B,CDC25C,CDC26,CDC27,CDC45,CDC6,CDC73,CDCA5,CDK1,CDK10,CDK2,CDK2AP2,CDK4,CDK5RAP2,CDK6,CDKN1A,CDKN1B,CDKN1C,CDKN2B,CDKN2D,CENPE,CENPF,CENPJ,CEP164,CEP192,CEP250,CEP41,CEP57,CEP63,CEP72,CEP78,CHEK2,CHMP4C,CKAP5,CLASP1,CNOT1,CNOT10,CNOT11,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT8,CNTRL,CRADD,CSNK1D,CSNK1E,CTDSP1,CTDSP2,CTDSPL,CUL1,CUL3,CUL4A,CYP1A1,DACT1,DBF4B,DCTN1,DCTN3,DCUN1D3,DDB1,DDRGK1,DDX3X,DLGAP5,DONSON,DUSP1,DYNC1H1,DYNC1LI1,DYNLL1,E2F1,E2F4,E2F7,E2F8,ECD,EGFR,EP300,ERCC2,ERCC3,ESPL1,EZH2,FAM83D,FANCI,FBXL7,FBXO31,FBXO5,FBXO7,FBXW7,FGF10,FGFR1OP,FOXN3,FOXO4,FZR1,GADD45A,GEN1,GIGYF2,GJC2,GML,GPNMB,GPR132,GTSE1,H2AFY,HAUS2,HAUS3,HAUS4,HAUS6,HAUS7,HAUS8,HECW2,HMGA2,HMMR,HSPA2,HUS1,HUS1B,ID2,IK,INO80,JADE1,KANK2,KCNA5,KCNH5,KLHL22,LCMT1,LSM11,MAD1L1,MAD2L1,MAD2L1BP,MAD2L2,MAPRE1,MDM2,MDM4,MECP2,MEN1,MEPCE,MIIP,MOS,MRE11,MRNIP,MTA3,MTBP,MUC1,MUS81,MYO16,NAE1,NBN,NDC80,NEDD1,NEK10,NEK11,NEK6,NEUROG1,NINL,NOP53,NPM1,NPM2,NSMCE2,ODF2,ORAOV1,OVOL1,PAF1,PAFAH1B1,PAGR1,PAXIP1,PBX1,PCBP4,PCID2,PCM1,PCNA,PCNT,PDPN,PHOX2B,PID1,PIDD1,PINX1,PKD1,PKD2,PKIA,PLAGL1,PLCB1,PLK1,PLK2,PLK3,PLK4,PLK5,PML,PPP1R9B,PRKACA,PRKAR2B,PRKDC,PRMT1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTEN,RAD17,RAD21,RAD51B,RAD51C,RB1,RCC2,RDX,RFWD3,RGCC,RINT1,RNASEH2B,RPA2,RPS27A,RPS27L,RPTOR,SFI1,SFN,SIRT2,SLFN11,SMARCA4,SOX4,SSNA1,STXBP4,SUSD2,TAF1,TERT,TEX14,TFDP2,TGFB1,TICRR,TMOD3,TNKS1BP1,TOPAZ1,TOPBP1,TP53,TP63,TP73,TPR,TPRA1,TPX2,TRIAP1,TRIP13,TTK,TUBA1A,TUBB,TUBB4A,TUBB4B,UBC,UBE2C,UBE2D1,UBE2E1,UBE2E2,USP47,VPS4A,VPS4B,WNT10B,XPC,YWHAE,YWHAG,ZFP36L1,ZFP36L2,ZFYVE19,ZNF16,ZNF207,ZNF385A,ZNF830,ZW10	TetrapodAncestor	101.589
GO.Biological.Process	GO:0030324	lung.development	327	2.834850e-106	3.661776e-102	1.119809e-104	1.244331e+0	AARD,ABCA12,ACVR2B,ADA,ADAMTS2,ADAMTSL2,AGR2,ARG1,ASCL1,ASXL1,ATXN1L,BAG6,BMP4,BMPR1A,BMPR2,CCBE1,CCDC40,CEBPA,CELSR1,CHI3L1,CREB1,CRISPLD2,CTGF,CTNNB1,CTSH,CTSZ,CYP1A2,DHCR7,DLG5,DNAAF1,DPPA2,DPPA4,EDN2,EGFR,EIF4E,EIF4EBP1,EP300,EPAS1,ERRFI1,ESRP2,EYA1,FGF1,FGF10,FGF18,FGF7,FGF9,FGFR1,FGFR2,FLT4,FOXA1,FOXF1,FOXJ1,FOXP2,FSTL3,GATA6,GLI2,GLI3,GPC3,GRHL2,HEG1,HES1,HHEX,HIKESHI,HMGB1,HS6ST1,HSD11B1,HSPB11,ID1,IGFBP5,ITGA3,JMJD6,KLF2,KRAS,LAMA5,LIF,LIPA,LOX,LOXL3,MAN1A2,MAN2A1,MAPK1,MAPK3,MMP14,MYCN,MYOCD,NFIB,NOG,NOS3,NOTCH1,NPHP3,NUMB,PDGFA,PDGFRB,PDPN,PGR,PHEX,PHF14,PITX2,PKD1,PKDCC,PROX1,PTK7,PTN,RBP4,RBPJ,RC3H2,RDH10,RSPO2,SEC24B,SIM2,SLC23A1,SMAD2,SOX11,SOX9,SPRY1,SPRY2,SREBF1,SRF,STRA6,TAB1,TBX5,TCF21,TGFBR2,THRA,THRB,TIMELESS,TNC,TNS3,VANGL2,VEGFA,WNT11,WNT5A,WNT7B,ZFPM2,ZIC3	TetrapodAncestor	101.436
GO.Biological.Process	GO:0002695	negative.regulation.of.leukocyte.activation	328	4.294662e-106	5.547415e-102	1.691285e-104	1.330514e+0	ABR,ADGRF5,ADORA2A,ANXA1,ARG1,ARG2,ATM,AXL,BANK1,BCL6,BCR,BMP4,BPI,BTK,CASP3,CCR2,CD274,CD300A,CD300LF,CD74,CEBPB,CLEC4G,CNR1,CNR2,CTLA4,DLG1,DLG5,DTX1,DUSP22,DUSP3,ERBB2,FAM19A3,FAS,FBXO7,FER,FOXF1,FOXJ1,FOXP3,GAL,GLI3,GNRH1,GPER1,GPNMB,HAVCR2,HLX,HMGB1,HMGB3,HMOX1,IDO1,IFNA2,IFNB1,IFNL1,IHH,IL10,IL13RA2,IL2,IL20RB,IL31RA,IL4,INHA,INHBA,INPP5D,IRF1,ITCH,JAK3,LAX1,LDLR,LGALS3,LGALS9,LILRB2,LOXL3,LRRC32,LST1,LYN,MAD1L1,MERTK,MILR1,NDFIP1,NFKBID,NR1H3,PAG1,PAWR,PDCD1LG2,PDE5A,PELI1,PGLYRP1,PGLYRP2,PGLYRP3,PKN1,PLA2G2D,PLA2G2F,PRDM1,PRKAR1A,PTPN22,RC3H1,RHBDD3,RIPOR2,SAMSN1,SCGB1A1,SDC4,SFRP1,SLA2,SMAD7,SOCS5,SOCS6,SOX11,SPN,TARM1,TBC1D10C,TGFB1,THOC1,TIGIT,TMEM131L,TNFAIP3,TNFAIP8L2,TNFRSF13B,TNFRSF14,TNFRSF21,TNFSF18,TSPAN32,TYRO3,VSIG4,VTCN1,XCL1,ZC3H12A,ZC3H8	TetrapodAncestor	101.256
GO.Biological.Process	GO:1901361	organic.cyclic.compound.catabolic.process	329	8.868168e-106	1.145501e-101	3.481767e-104	1.229618e+0	AADAT,ACMSD,ADA,ADA2,ADPRM,AFMID,AGO1,AGO3,AGO4,AHCY,AICDA,AKR1D1,ALDH1L1,ALDH1L2,ALDH4A1,ALDH6A1,ALLC,AMBP,AOX1,APOBEC1,APOBEC2,APOBEC3A,APOBEC3C,APOBEC3F,APOBEC3G,APOBEC3H,APOE,ATM,CARNMT1,CARNS1,CASC3,CASP3,CDA,CECR2,CEL,CNOT1,CNOT10,CNOT11,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT8,CSDE1,CTIF,CYP1A1,CYP1A2,CYP24A1,CYP27B1,CYP2A6,CYP39A1,CYP46A1,CYP7A1,DBH,DCP2,DCPS,DDX5,DEDD2,DERA,DFFA,DFFB,DIO3,DIS3L2,DNA2,DNASE1,DNASE1L1,DNASE1L2,DNASE1L3,DNASE2,DPYD,DROSHA,DXO,EDC3,EDC4,EIF3E,EIF4A1,EIF4A2,EIF4A3,EIF4E,ENDOG,ENPP1,ENPP3,ENPP4,ENSG00000265303,ENSG00000282246,ENTPD2,ENTPD3,ENTPD4,ENTPD5,ENTPD6,ENTPD7,EPHX2,ERN1,ERN2,ETF1,EXOSC1,EXOSC10,EXOSC2,EXOSC3,EXOSC4,EXOSC5,EXOSC6,EXOSC7,EXOSC9,FAH,FBXO18,FEN1,FGF23,FTCD,GALT,GDA,GSPT1,GSTZ1,H1F0,HAAO,HBS1L,HDC,HGD,HINT1,HMGB1,HMGB2,HMOX1,HMOX2,HNMT,HNRNPD,HPD,HPRT1,HSD17B14,IDO1,IDO2,IL4I1,ISG20,ITPA,KHSRP,KMO,KPNA1,KPNB1,KYAT1,KYNU,LIN28A,LIN28B,LRTOMT,LSM1,LSM3,LSM5,LSM7,MAGOH,MAGOHB,MAOA,MAOB,METTL14,METTL3,MLH1,MOXD1,MRTO4,MTHFS,MTPAP,MUS81,NANOS2,NBAS,NCBP1,NCBP2,NEIL1,NEIL2,NOCT,NT5C,NT5C1A,NT5C1B,NT5C3A,NT5E,NT5M,NTHL1,NUDT1,NUDT12,NUDT15,NUDT16,NUDT18,NUDT4,NUDT5,NUDT7,NUDT9,OGG1,PABPC4,PAH,PAIP1,PAN2,PAN3,PAPD4,PARN,PARP9,PATL1,PCBD1,PCID2,PDE10A,PDE12,PDE1A,PDE1B,PDE2A,PDE3A,PDE4A,PDE4B,PDE4D,PDE5A,PDE7B,PDE8A,PDE8B,PDE9A,PDXP,PELO,PNLDC1,PNP,PNPT1,PNRC1,PNRC2,POLR2D,POLR2G,PPP1R8,PPP2R2A,PRODH,PRODH2,PRPF18,PYM1,QDPR,RBM8A,RC3H1,RNASEH1,RNASEH2A,RNASEH2B,RNASEH2C,RNASET2,RNH1,RNPS1,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL23,RPL23A,RPL24,RPL27,RPL28,RPL29,RPL3,RPL30,RPL31,RPL34,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL5,RPL6,RPL7,RPL7A,RPL8,RPLP0,RPLP2,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS17,RPS18,RPS20,RPS21,RPS23,RPS24,RPS25,RPS26,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS4X,RPS5,RPS6,RPS7,RPS8,RPSA,SAMD4A,SAMD4B,SAMHD1,SCARB1,SETMAR,SIDT2,SKIV2L2,SLC6A3,SLFN14,SMG1,SMG5,SMG6,SMG7,SMG8,SMPDL3A,SND1,SNX17,SPO11,SRD5A2,STK31,STS,SULT2A1,TAT,TATDN1,TDG,TDO2,TET2,THRAP3,TNKS1BP1,TRERF1,TTC37,TYMP,UGT1A1,UGT1A4,UNG,UPB1,UPF1,UPF2,UPF3A,UPP1,UROC1,VCP,WDR61,XDH,XRN1,YWHAH,ZC3H12A,ZCCHC11,ZCCHC6,ZFP36,ZFP36L1,ZFP36L2,ZHX2,ZPR1	TetrapodAncestor	100.941
GO.Biological.Process	GO:0000902	cell.morphogenesis	330	1.044483e-105	1.349159e-101	4.088360e-104	1.123371e+0	ABI1,ABL1,ACTN1,ADAM8,ADARB1,ADD1,ADGRB1,ADORA2A,AFG3L2,ALCAM,ALS2,ANK3,ANKRD27,ANOS1,ANTXR1,APBB2,APP,AR,ARC,ARHGAP35,ARHGEF2,ARHGEF26,ARL13B,ARTN,ARX,ASXL1,ATOH1,ATP8A2,AURKA,AUTS2,AXL,B3GNT2,BCL11B,BCL2,BCL6,BDNF,BIN3,BMP7,BMPR1B,BOC,BRSK1,BRSK2,BTBD3,BVES,C1GALT1C1,C21orf59,C9orf72,CABP4,CAMK2A,CAP1,CAP2,CASP3,CASP9,CCK,CCKAR,CDC42,CDH11,CDH4,CDK5,CDK5R1,CELSR2,CHL1,CHRNB2,CIB1,CLDN3,CLEC1B,CLIC5,CLU,CNTN2,CNTN4,CNTNAP2,COBL,COL18A1,COL25A1,CREB1,CRMP1,CSF1R,CSNK1A1,CTNNA2,CTNNB1,CTNND2,CTTN,CUL3,CXCR4,CYFIP1,CYFIP2,DAB1,DAB2IP,DACT2,DBNL,DCC,DDR1,DKK1,DLG4,DLX5,DMRT1,DNM2,DOCK10,DOK1,DOK2,DOK4,DOK5,DOK6,DPYSL2,DPYSL4,DPYSL5,DRAXIN,DRD2,DSCAM,DSCAML1,DTNBP1,DVL1,DYNLT1,ECT2,EFNA1,EFNA3,EFNA4,EFNA5,EFNB1,EFNB2,EFNB3,EGFR,EGR2,EIF2AK4,EMX1,ENAH,ENSG00000173366,ENSG00000251246,ENSG00000265590,EP300,EPB41L3,EPB41L5,EPHA1,EPHA2,EPHA4,EPHA5,EPHA7,EPHA8,EPHB1,EPHB2,EPHB3,EPYC,ERBB2,ETV1,EVL,EXT1,EZR,FAM129B,FARP1,FBXO45,FER,FERMT2,FERMT3,FEZ1,FEZ2,FEZF1,FGFR2,FLNA,FLNB,FLOT1,FLRT1,FLRT2,FLRT3,FMN1,FN1,FOXG1,FRMD6,FRS2,FRY,FRYL,FZD3,FZD4,FZD7,GAB1,GAB2,GAP43,GATA3,GBX1,GBX2,GDNF,GFRA1,GFRA2,GFRA3,GFRA4,GJA1,GJE1,GLI2,GLI3,GP1BA,GP5,GPC1,GPM6A,GRB10,GRB2,GRB7,GREM1,GRHL2,HEG1,HES1,HGF,HPRT1,HRAS,HRH2,ID1,IHH,IL7R,IQGAP1,IRS2,ISL1,ISPD,ITGA1,ITGA4,ITGA8,ITGAV,ITGB1,ITGB7,KIF20B,KIF5A,KIF5B,KIF5C,KIRREL1,KIRREL3,KLF2,KLF7,KRAS,L1CAM,LAMA2,LAMA5,LAMB1,LAMC3,LATS1,LEF1,LHFPL5,LHX1,LHX2,LHX4,LINGO1,LINGO4,LIPA,LLPH,LMX1A,LRFN1,LRFN2,LRFN4,LRP4,LRRC38,LRRC55,LRRC70,LRRK2,LRRN2,LST1,LYPLA2,MAEL,MAP1B,MAP1S,MAP2,MAP4K4,MAP6,MAP6D1,MAPK1,MAPK14,MAPK3,MATN1,MATN2,MEF2A,MEF2C,MERTK,MET,METTL3,MINK1,MSX1,MYH9,NBEAL2,NBL1,NCAM1,NDEL1,NECTIN1,NEFH,NEFL,NEK3,NEO1,NES,NFASC,NFIB,NGF,NGFR,NLGN3,NOG,NOTCH1,NOTCH4,NOX4,NPHS1,NPTX1,NR4A2,NR4A3,NRAS,NRG1,NRK,NRN1L,NRP1,NRP2,NRTN,NRXN1,NRXN3,NTF3,NTF4,NTN3,NTNG1,NTNG2,NTRK1,NUMB,NUMBL,NYAP1,NYAP2,OGN,OMG,OPHN1,OR10A4,OTX2,P2RX7,PACSIN2,PAFAH1B1,PAK1,PAK3,PALLD,PARD3,PARD6B,PAX2,PDLIM7,PDPN,PDZD7,PEAK1,PHOX2B,PICALM,PIK3CA,PIK3CD,PIK3R1,PITPNA,PLA2G10,PLCG1,PLEKHO1,PLPPR4,PLXNA1,PLXNA2,PLXNA3,PLXNA4,PLXNB1,POF1B,POU4F1,POU4F3,PPP3CB,PRKCA,PRKCQ,PRKCZ,PROX1,PSPN,PTCH1,PTEN,PTK2,PTPN11,PTPRA,PTPRM,PTPRO,PTPRZ1,RAB1A,RAB25,RAB8A,RAC1,RADIL,RANBP9,RAP1GAP,RAPH1,RB1,RBFOX2,RELN,RERE,RET,RILPL1,ROBO1,ROBO2,ROBO3,RPL24,RPS6KA5,RTN4R,RYK,S100A6,S100B,SCFD1,SCN1B,SCRIB,SDC2,SEC24B,SEMA3A,SEMA3C,SEMA4A,SEMA6A,SEMA6C,SEMA7A,SGK1,SH3GL2,SH3KBP1,SHANK1,SHC1,SHC3,SHROOM3,SIAH1,SIAH2,SIDT2,SIPA1L3,SLC1A3,SLC39A3,SLC9A3R1,SLIT1,SLIT2,SLIT3,SLITRK1,SLITRK2,SLITRK3,SLITRK4,SLITRK5,SLITRK6,SMAD4,SNX1,SNX2,SOD1,SOS1,SOX17,SPG11,SPON2,SPTB,SPTBN2,SPTBN5,SRC,SRCIN1,SRF,SRGAP2,SS18,ST14,STC1,STK24,STK26,STK4,STMN1,STRADB,STRC,STXBP1,SZT2,TAL1,TBC1D20,TBCD,TEK,TENM1,TENM2,TENM3,TENM4,TFCP2L1,TGFB2,THOC2,TIAM1,TLR9,TMEM106B,TMEM108,TNFRSF8,TNMD,TNN,TNR,TRAK1,TRAK2,TRIM46,TSKU,TUBB3,TYRO3,UCHL1,UGT8,ULK2,UNC5A,UNC5B,UNC5C,UNC5D,UPK3A,USP9X,VAMP3,VANGL2,VASP,VAX2,VCL,VDR,VEGFA,VLDLR,VSIG1,WASF2,WDR1,WNT3,WNT3A,WNT5A,WNT7A,WNT7B,YTHDF2,ZFPM1,ZNF335,ZNF365,ZNF385A	TetrapodAncestor	100.87
GO.Biological.Process	GO:0036294	cellular.response.to.decreased.oxygen.levels	331	1.066408e-105	1.377479e-101	4.161569e-104	1.316645e+0	ACAA2,ADAM8,AIFM1,ANGPT4,ANKRD1,AQP1,AQP3,BACH1,BAD,BCL2,BMP7,BNIP3,BNIP3L,BRIP1,CA9,CARD16,CASR,CBL,CCNA2,CCNB1,CFLAR,CITED2,CLCA1,COX4I2,CPEB1,CPEB2,CPEB4,CUL2,CYBB,DNM1L,DNMT3A,E2F1,EDN1,EEF2K,EGLN1,EGLN2,EGLN3,EGR1,EIF4EBP1,ELOB,ELOC,ENDOG,EP300,EPAS1,EPO,ERO1A,FABP1,FAM162A,FMN2,GATA6,GNGT1,HIF1A,HIF1AN,HIF3A,HIGD1A,HIPK2,HMOX1,HYOU1,IRAK1,KCND2,KCNK2,KCNK3,KCNMB1,LIMD1,LMNA,MDM2,MDM4,MGARP,MTOR,MYC,NDNF,NDRG1,NKX3-1,NOP53,NOTCH1,NPEPPS,OPA1,OPRD1,P4HB,PCK1,PDK3,PGK1,PICK1,PINK1,PLK3,PMAIP1,PPARD,PPARGC1A,PRKAA1,PRKCE,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTEN,PTGIS,PTN,RBPJ,RGCC,RPS27A,S100B,SFRP1,SIRT1,SIRT2,SIRT4,SLC29A1,SLC8A1,SLC8A3,SLC9A1,SRC,STC1,STC2,SUV39H2,TBL2,TERT,TIGAR,TP53,TRPC6,TWIST1,UBC,UBE2D1,UBE2D2,UBE2D3,UBQLN1,UCN3,VEGFA,ZFP36L1	TetrapodAncestor	100.861
GO.Biological.Process	GO:0001558	regulation.of.cell.growth	332	1.172927e-105	1.515070e-101	4.563463e-104	1.187418e+0	ABL1,ACVR1B,ACVRL1,ADAM15,ADIPOR1,ADIPOR2,ADNP,ADNP2,AGT,AGTR1,AGTR2,AKAP6,ANAPC2,APBB2,APOE,ARHGAP4,ARHGEF11,AVP,AVPR1A,BAP1,BCAR1,BCL11A,BCL2,BCL6,BDKRB1,BDNF,BLZF1,BMP10,BMPR2,BRAT1,BST2,BTG1,CAMK2D,CAPRIN2,CAV3,CCAR2,CCDC85B,CD38,CDA,CDC42,CDC73,CDH4,CDHR2,CDK19,CDK5,CDK5R1,CDKL5,CDKN1A,CDKN1B,CDKN2A,CDKN2AIP,CDKN2C,CDKN2D,CHPT1,CIB1,CISH,CPNE5,CPNE6,CRABP2,CRIM1,CRLF3,CRYAB,CSNK2A1,CSNK2A3,CTDP1,CTGF,CTTN,CXCL16,CYBA,CYFIP1,CYP27B1,CYR61,DACT3,DCBLD2,DCC,DCUN1D3,DDR1,DDX3X,DERL2,DISC1,DNM2,DPYSL2,DRAXIN,DSCAM,EBAG9,EDN1,EFNA5,EGFR,EGLN2,EI24,EIF4G2,ENPP1,EPB41L3,EPHA7,ERBB2,ESM1,ESR2,EXOSC2,EXOSC4,EXOSC9,EXTL3,F2,FAM107A,FBLN5,FBP1,FGF13,FGFR1OP,FLCN,FN1,FSTL4,FXN,FXYD2,G6PD,GAL,GDF2,GDI1,GJA1,GOLGA4,GREM1,GSK3A,H3F3A,H3F3C,HAMP,HBEGF,HDGFL2,HNF4A,HPN,HRG,HTRA1,HTRA3,HTRA4,IFRD1,IGF1,IGFBP2,IGFBP4,IGFBP5,IGFBP6,IGFBP7,IGFBPL1,IL17RB,IL2,IL9,INHBA,INO80,INS,ISLR2,IST1,ITCH,ITSN2,JADE1,KAZALD1,KDM2B,KIAA1109,KIF26A,KRT17,L1CAM,LAMTOR2,LEF1,LIMK1,LMX1A,LPAR3,LTBP4,LUZP4,MACF1,MAD2L2,MAG,MAP1B,MAPT,MEGF8,MMP14,MSX1,MTOR,MTPN,MUC12,MUL1,MYOCD,N6AMT1,NAIF1,NANOS1,NCBP1,NDEL1,NDRG3,NDUFS3,NEDD4L,NET1,NKX6-1,NOV,NPR1,NRG1,NRG3,NRP1,NTRK3,OGFR,OLFM1,OSGIN1,OSGIN2,OSTN,PAFAH1B1,PAK1,PAPPA2,PHB,PIN1,PLAA,PLCE1,PLXNA1,PLXNA2,PLXNA3,PLXNA4,PML,PPARD,PPARG,PPP1R9B,PPT1,PRKCQ,PRKN,PRSS2,PSMD10,PTK2B,PTPRJ,PTPRS,RAB21,RASAL1,RASGRP2,RB1,RBBP7,RERG,RIMS1,RND2,RNF6,ROS1,RPS6KA1,RPS6KA3,RPTOR,RTN4,RTN4R,RUFY3,S100A8,S100A9,SCGB3A1,SDCBP,SEMA3A,SEMA3G,SEMA4D,SEMA5A,SEMA7A,SERPINE2,SERTAD2,SESN2,SFN,SFRP1,SFRP2,SGK1,SGK2,SH3BP4,SIPA1,SIRT1,SLC25A33,SLC9A1,SLIT2,SLIT3,SMAD4,SMARCA2,SMARCA4,SMURF1,SOCS2,SOX17,SPHK1,SPOCK1,SPP1,SRF,ST7L,SYT1,SYT17,SYT2,SYT4,TAF9,TAF9B,TAOK2,TGFB1,TGFB2,TGFBR1,TMC8,TMEM97,TNFRSF12A,TNR,TP53,TP53TG5,TRIM32,TRO,TRPC5,TSG101,TTL,TWF2,UCN,ULK2,UNC13A,USP47,UTS2R,VEGFA,WDR36,WFDC1,WISP1,WISP2,WNT11,WNT3,WNT3A,WNT5A,ZFYVE27,ZNF639	TetrapodAncestor	100.82
GO.Biological.Process	GO:0032869	cellular.response.to.insulin.stimulus	333	1.524306e-105	1.968946e-101	5.912751e-104	1.353564e+0	ADIPOQ,AKT2,AP3S1,APC,APOBEC1,APPL1,ATP6AP1,ATP6V0A4,ATP6V0B,ATP6V0C,ATP6V0D1,ATP6V0D2,ATP6V0E1,ATP6V0E2,ATP6V1B1,ATP6V1B2,ATP6V1C1,ATP6V1C2,ATP6V1D,ATP6V1E1,ATP6V1E2,ATP6V1G1,ATP6V1G3,ATP6V1H,BAIAP2L2,BCAR1,C2CD5,CAPN10,CAV2,CCL2,CDK4,CFLAR,CPEB1,CPEB2,CYFIP1,DENND4C,EEF2K,EIF4EBP1,ENPP1,ENSG00000278139,ERRFI1,FER,FOXC2,FOXO1,FOXO4,GAB1,GCK,GHRHR,GHSR,GOT1,GPLD1,GRB2,GSK3A,GSTP1,HDAC5,HDAC9,IDE,IGF1R,IGF2,INHBB,INPP5K,INS,IRS1,IRS2,IRS4,KAT2B,KL,LPIN1,NDEL1,PAK1,PARP1,PCK1,PDK2,PDPK1,PHIP,PIK3C2A,PIK3CA,PIK3R1,PIK3R2,PIK3R3,PKLR,PKM,PLA2G1B,PPARG,PRKCI,PRKCZ,PRKDC,PTEN,PTPN1,PTPRA,RAB13,RAB31,RAB8A,RHOQ,RPE65,SH2B2,SHC1,SLC25A33,SLC2A8,SLC9A1,SMARCC1,SOCS7,SOGA1,SORBS1,SOS1,SP1,SRC,SRD5A1,SREBF1,SRSF5,STAR,STXBP4,TBC1D4,TCIRG1,TRIB3,TUSC5,UCP2,USF1,VAMP2,WDTC1,XBP1,YWHAG,ZFP36L1,ZNF106	TetrapodAncestor	100.706
GO.Biological.Process	GO:0008544	epidermis.development	334	2.255677e-105	2.913658e-101	8.723527e-104	1.233479e+0	ABCA12,ACER1,ACVR1B,ADAM9,AGPAT2,ALDH3A2,ALX4,ANXA1,APCDD1,ATOH1,BCL11B,BCL2,BNC1,CALML5,CAPN1,CASP14,CASP3,CD109,CDC42,CDH3,CELA2A,CELSR1,CERS3,CLIC5,CNFN,COL7A1,CRABP2,CST6,CSTA,CTGF,CTNNB1,CYP26B1,DCT,DKK1,DLL1,DNASE1L2,DSC1,DSC2,DSC3,DSG1,DSG2,DSG3,DSG4,DSP,EDA,EDA2R,EDAR,EGFR,ELF3,EMP1,EPHA2,ERCC2,ERCC3,EREG,EVPLL,EXPH5,FA2H,FABP5,FGF10,FGF7,FGFR1,FGFR2,FLG,FLNB,FLOT2,FOSL2,FOXE1,FOXN1,FOXQ1,FURIN,FUZ,FZD3,FZD6,GJB5,GNAS,GORAB,GRHL2,GRHL3,GRXCR1,HDAC1,HDAC2,HES1,HES5,HOXC13,HRNR,IFT172,IFT74,IGFBP5,INHBA,INTU,IRF6,IVL,JAG1,JAG2,JUP,KAZN,KDF1,KLF4,KRT1,KRT10,KRT12,KRT13,KRT14,KRT15,KRT16,KRT17,KRT19,KRT2,KRT20,KRT23,KRT24,KRT25,KRT26,KRT27,KRT28,KRT31,KRT32,KRT33A,KRT33B,KRT34,KRT35,KRT36,KRT37,KRT38,KRT39,KRT40,KRT5,KRT6A,KRT6B,KRT6C,KRT7,KRT71,KRT72,KRT73,KRT74,KRT75,KRT76,KRT77,KRT80,KRT81,KRT82,KRT83,KRT84,KRT85,KRT86,KRT9,KRTAP1-1,KRTAP1-5,KRTAP10-1,KRTAP10-10,KRTAP10-11,KRTAP10-12,KRTAP10-2,KRTAP10-4,KRTAP10-5,KRTAP10-6,KRTAP10-7,KRTAP10-8,KRTAP10-9,KRTAP11-1,KRTAP12-1,KRTAP12-3,KRTAP12-4,KRTAP13-1,KRTAP13-3,KRTAP13-4,KRTAP15-1,KRTAP17-1,KRTAP19-1,KRTAP19-5,KRTAP19-8,KRTAP2-1,KRTAP2-2,KRTAP2-3,KRTAP2-4,KRTAP20-2,KRTAP21-1,KRTAP21-2,KRTAP21-3,KRTAP23-1,KRTAP24-1,KRTAP27-1,KRTAP29-1,KRTAP3-1,KRTAP3-2,KRTAP3-3,KRTAP4-1,KRTAP4-11,KRTAP4-2,KRTAP4-4,KRTAP4-5,KRTAP4-6,KRTAP4-7,KRTAP4-8,KRTAP4-9,KRTAP5-1,KRTAP5-2,KRTAP5-3,KRTAP5-5,KRTAP5-6,KRTAP8-1,KRTAP9-1,KRTAP9-2,KRTAP9-6,KRTAP9-7,LAMA3,LAMA5,LAMB3,LATS1,LCE1F,LCE2D,LCE3A,LCE3E,LCE5A,LCE6A,LDB2,LELP1,LGR4,LGR5,LHFPL5,LHX2,LIPK,LIPM,LIPN,LOR,LRP4,LRTOMT,MCOLN3,NF1,NOTCH1,NSDHL,NSUN2,NTF4,OVOL1,OVOL2,PAFAH1B1,PALLD,PCSK6,PDGFA,PDZD7,PERP,PI3,PIP5K1A,PITX2,PKP1,PKP2,PKP3,POU2F3,POU3F2,POU4F3,PPARA,PPHLN1,PPL,PRR9,PRSS8,PTCH1,PTCH2,PTHLH,RBP2,RBPJ,RELA,RPTN,S100A7,SATB1,SCEL,SCRIB,SEC24B,SFN,SHARPIN,SLC4A7,SLC9A3R1,SLITRK6,SMO,SNAI1,SOD1,SOS1,SOSTDC1,SOX18,SOX9,SPINK5,SPINK6,SPINK9,SPRR1A,SPRR1B,SPRR2A,SPRR2D,SPRR2F,SPRR2G,SPRR3,SPRR4,ST14,STK4,STRC,STS,TCHH,TGFB2,TGM1,TGM3,TMC1,TMEM79,TNFRSF19,TP63,TRPC4AP,TSG101,TXNIP,UGCG,USH1C,USH2A,VANGL2,WNT10A,WNT16,WNT5A,ZDHHC21,ZNF750	TetrapodAncestor	100.536
GO.Biological.Process	GO:0061035	regulation.of.cartilage.development	335	2.991051e-105	3.863541e-101	1.153296e-103	1.361158e+0	ACVRL1,ADAMTS12,ADAMTS7,AXIN2,BMP1,BMP10,BMP2,BMP4,BMP6,BMPR1B,BMPR2,CARM1,CTGF,CTNNB1,CYR61,EFEMP1,FGF18,GDF2,GDF5,GDF6,GLG1,GLI2,GLI3,GREM1,LEP,LOXL2,MAF,NKX3-2,NOG,PKDCC,POR,PTH,PTHLH,RARA,RARB,RARG,RELA,RFLNA,RFLNB,RUNX2,SCIN,SCX,SHOX2,SIX2,SNAI2,SOX5,SOX9,TAPT1,TGFB1,TGFBR1,TRPS1,WNT11,WNT5A,WNT9A,ZBTB16	TetrapodAncestor	100.413
GO.Biological.Process	GO:0001707	mesoderm.formation	336	3.238632e-105	4.183341e-101	1.245042e-103	1.408255e+0	BMP4,BMP7,BMPR1A,BMPR2,CHRD,CRB2,DKK1,EOMES,EPB41L5,EPHA2,EXOC4,EXT2,EYA1,EYA2,FGFR2,FOXC1,FOXC2,FOXF1,HAND1,HMGA2,INHBA,ITGA2,ITGA3,ITGA8,ITGB1,ITGB4,KDM6A,KDM6B,KLF4,LEF1,MESP1,MESP2,MSGN1,NF2,NOG,NR4A3,PAX2,POFUT2,PRKACA,PRKAR1A,SCX,SIX2,SMAD2,SNAI1,SRF,T,TAL1,TBX20,TBX6,TLX2,TXNRD1,WLS,WNT11,WNT3,WNT3A,WNT5A	TetrapodAncestor	100.378
GO.Biological.Process	GO:0071407	cellular.response.to.organic.cyclic.compound	337	1.014235e-104	1.310087e-100	3.887500e-103	1.160473e+0	AACS,AANAT,ABCA1,ABCB4,ABCC2,ABHD2,ABL1,ACTR2,ADAR,ADCY2,ADCY3,ADCY5,ADCYAP1,ADIPOQ,AGO1,AGO2,AGO3,AGO4,AGTR2,AIF1,AIFM1,AKAP6,ALPL,ANKRD1,ANXA1,AOC1,APEX1,APLP1,APP,AQP1,AQP8,AR,ARG1,ARID1A,ATF4,ATP1A1,ATP1A2,ATP2B1,ATP2B4,BAD,BGLAP,BMP2,BMP4,BMP7,BRCA1,BTRC,CACNA1S,CALCOCO1,CALR,CARM1,CASP3,CASP6,CASP8,CASP9,CASQ2,CASR,CAV1,CCL2,CCL3,CCL5,CCNA2,CCNB1,CCNE1,CDC5L,CDH1,CDK4,CDK7,CDKN1B,CEBPA,CEBPB,CFLAR,CFTR,CHEK2,CIB2,COL1A1,COLEC12,CPS1,CRHBP,CTNNA1,CTNNB1,CYBA,CYP1A1,CYP1B1,CYP24A1,CYP7A1,DAXX,DDIT4,DDX17,DDX18,DDX5,DDX54,DDX58,DHX9,DIAPH1,DMTN,DNAJA1,DNM1L,DNM2,DNMT3B,DRD1,DRD5,DROSHA,DYNAP,EDN1,EEF2K,EFNA5,EGFR,EGLN2,EGR1,EIF4E,EIF4EBP1,ELK1,EPHX1,ERRFI1,ESR1,ESR2,ESRRA,ESRRB,ESRRG,EZH2,EZR,FAM210B,FBXO32,FDX1,FGF23,FHL2,FIS1,FKBP4,FLOT1,FOXF1,FOXO1,GABPA,GABRB1,GABRB2,GABRB3,GABRG2,GCLM,GDAP1,GLI2,GNAI1,GNG2,GPD1,GPER1,GPLD1,GRIP1,GSK3A,GSTM2,GSTP1,H2AFZ,HAMP,HCFC1,HCN1,HCN2,HCN3,HCN4,HDAC2,HDAC8,HEY1,HMGCS1,HNF4A,HNF4G,HNRNPA2B1,HNRNPD,HNRNPU,HSF1,HSP90AB1,HSP90B1,HSPA5,ID1,ID3,IFIT1,IFNB1,IGFBP5,IL10,IL15,IL18,IL1B,IL6,INHBA,INPP5K,IRF3,ISL1,ITGA2,ITPR2,JAK2,JUP,KAT5,KCNE1,KCNJ11,KCNMB1,KCNQ1,KDM1A,KDM3A,KIF18A,KLF2,KLF4,KLF5,KLF9,LARP1,LEF1,LGALS1,LIN28A,LIN28B,LRP6,LRP8,LRRK2,MAPK1,MAPK3,MB21D1,MBD2,MDM2,MED13,MED14,MED17,MED24,MED30,MED4,MEF2C,METTL21C,METTL3,MGARP,MLC1,MSN,MSR1,MSTN,MSX1,MSX2,MUL1,MYOD1,MYOG,NCBP1,NCOA1,NCOA3,NCOA4,NCOA6,NFATC4,NFKB1,NKX3-1,NOX4,NPAS4,NPC1,NPM1,NR0B1,NR0B2,NR1D1,NR1D2,NR1H2,NR1H3,NR1H4,NR1I2,NR2C1,NR2C2,NR2E3,NR2F6,NR3C1,NR4A1,NR4A2,NR4A3,NR5A2,NRIP1,NTRK1,OPRM1,OR51E2,P2RX4,P2RX7,P2RY1,P2RY6,PADI2,PAK2,PAK3,PAK4,PAQR5,PAQR6,PAQR7,PAQR8,PCK1,PDE12,PDE2A,PDE3A,PDE4B,PDE4D,PDGFB,PDXP,PENK,PGR,PGRMC2,PHB,PHEX,PIAS1,PIAS2,PIK3CG,PIM1,PKD2,PKLR,PLA2G4F,PLPP1,PMEPA1,POU4F1,PPARA,PPARD,PPARG,PPARGC1A,PPARGC1B,PPP1R9B,PQBP1,PRKACA,PRKN,PRKRA,PTAFR,PTCH1,PTN,RAD51,RAE1,RALB,RAP1A,RAP1B,RAPGEF1,RAPGEF2,RAPGEF3,RARA,RARB,RARG,RB1,RBFOX2,RBM14,RECQL5,RELA,REST,RIOK3,RNF14,RNF4,ROCK2,RORB,RORC,RUVBL2,RWDD1,RXRA,RXRB,RXRG,RYR1,RYR2,RYR3,SAFB,SFRP1,SHMT1,SIRT2,SLC16A1,SLC26A3,SLC34A1,SLC5A5,SLC6A4,SLC8A1,SLC8A3,SLC9A1,SMAD2,SMAD5,SMO,SMYD3,SNCA,SNIP1,SOD1,SOX10,SPIDR,SPOUT1,SPP1,SRC,SRD5A1,SRRT,SSTR1,SSTR2,SSTR3,SSTR4,SSTR5,STAR,STC1,TADA3,TAF1,TARBP2,TERT,TGFB1,TGFB1I1,TH,THRA,THRAP3,THRB,TIPARP,TLR3,TMEM173,TNC,TNF,TRIM71,TRIP4,TRPM2,TRPV1,TSN,TSNAX,UBE2L3,UBE3A,UBR5,UGT1A1,UGT3A2,USP8,VDR,WNT10B,XRN1,YAP1,YWHAH,ZC3H12A,ZC3H7A,ZCCHC11,ZFP36,ZFP36L1,ZFP36L2,ZNF703	TetrapodAncestor	99.8827
GO.Biological.Process	GO:0043436	oxoacid.metabolic.process	338	1.330988e-104	1.719237e-100	5.086501e-103	1.137153e+0	AACS,AADAT,AARS,AARS2,AARSD1,AASDHPPT,AASS,ABAT,ABCC2,ABCD1,ABCD2,ABCD3,ABHD10,ABHD14A-ACY1,ABHD14B,ABHD5,ACAA2,ACACA,ACACB,ACAD10,ACAD8,ACAD9,ACADL,ACADM,ACADS,ACADVL,ACAN,ACAT1,ACAT2,ACBD5,ACMSD,ACO1,ACOT1,ACOT11,ACOT12,ACOT2,ACOT4,ACOT6,ACOT7,ACOT8,ACOX2,ACOX3,ACOXL,ACSBG1,ACSBG2,ACSF2,ACSL1,ACSL3,ACSL4,ACSL5,ACSM1,ACSM2A,ACSM2B,ACSM3,ACSM4,ACSM5,ACSM6,ACSS1,ACSS2,ACY1,ADH7,ADI1,ADIPOQ,ADIPOR1,ADIPOR2,ADO,ADPGK,ADSS,ADSSL1,AFMID,AGMAT,AGXT,AGXT2,AHCY,AHCYL1,AHCYL2,AKR1A1,AKR1D1,ALDH1A3,ALDH1L1,ALDH1L2,ALDH3A2,ALDH4A1,ALDH5A1,ALDH6A1,ALDH7A1,ALDH8A1,ALDOA,ALDOB,ALKBH7,ALOX15,ALOX15B,ALOX5,ALOX5AP,AMACR,AMDHD2,ANGPT1,APIP,ARG1,ARG2,ART4,ARV1,ASL,ASNS,ASNSD1,ASPA,ASPG,ASS1,ATF4,ATIC,ATP8B1,AUH,AWAT1,AZIN1,AZIN2,B3GALT6,B3GAT1,B3GAT2,B3GAT3,B3GNT2,B3GNT3,B3GNT7,B4GALT1,B4GALT2,B4GALT3,B4GALT4,B4GALT5,B4GALT6,BAAT,BCAN,BCAT1,BCAT2,BCKDHA,BCKDHB,BCKDK,BCO2,BDH2,BGN,BLMH,BPGM,BPHL,BPNT1,BRCA1,BSG,BTD,C14orf159,C3,CARNMT1,CARNS1,CARS,CBR1,CBR4,CBS,CCDC12,CD74,CDO1,CEL,CES1,CES2,CH25H,CHST1,CHST11,CHST12,CHST14,CHST2,CHST3,CHST4,CHST5,CHST6,CHST7,CHST9,CHSY3,CKMT1A,CKMT1B,CKMT2,CLN3,CMAS,CPS1,CPT1A,CPT1B,CPT1C,CPT2,CRABP1,CRABP2,CRAT,CROT,CRTAP,CRYM,CS,CSAD,CSGALNACT1,CSGALNACT2,CSPG4,CTH,CTNS,CTPS1,CTPS2,CYB5A,CYB5R3,CYGB,CYP1A1,CYP1A2,CYP1B1,CYP26A1,CYP26B1,CYP26C1,CYP27A1,CYP27C1,CYP2A13,CYP2A6,CYP2A7,CYP2B6,CYP2C18,CYP2C19,CYP2C8,CYP2C9,CYP2D6,CYP2F1,CYP2J2,CYP2S1,CYP2W1,CYP39A1,CYP46A1,CYP4A11,CYP4F22,CYP4F8,CYP4V2,CYP7A1,CYP8B1,CYTL1,D2HGDH,DAGLA,DAGLB,DARS,DARS2,DBT,DCN,DCT,DCXR,DDAH1,DDC,DDO,DECR1,DEGS1,DHFR,DHFR2,DHTKD1,DLAT,DLD,DPEP1,DPYD,DSE,DSEL,EARS2,ECH1,ECHDC1,ECHDC2,ECHS1,ECI1,ECI2,EDN1,EDN2,EGFLAM,EGLN1,EGLN2,EGLN3,EHHADH,ELOVL1,ELOVL2,ELOVL3,ELOVL4,ELOVL6,ELOVL7,ENO3,ENO4,ENOSF1,ENPP1,ENSG00000249319,ENSG00000255730,ENSG00000255835,ENSG00000256591,ENSG00000260300,ENSG00000260643,ENSG00000269547,ENSG00000276490,ENSG00000284512,EPHX2,EPRS,ERO1A,ERO1B,ETFA,ETFB,EXT1,EXT2,EXTL2,EXTL3,FA2H,FAAH,FABP3,FADS1,FADS2,FADS3,FADS6,FAH,FAM213B,FARS2,FARSA,FASN,FDXACB1,FH,FMOD,FN3K,FOLH1,FPGS,FTCD,GADL1,GAPDH,GAPDHS,GARS,GART,GATB,GATC,GBA2,GCAT,GCDH,GCH1,GCK,GCLM,GCSH,GFPT1,GFPT2,GGH,GGT1,GGT2,GGT5,GGT7,GGTLC2,GGTLC3,GHR,GLB1,GLCE,GLDC,GLO1,GLUD1,GLUD2,GLUL,GLYAT,GLYATL1,GLYATL2,GMPS,GNE,GNMT,GNS,GOT1,GOT1L1,GOT2,GPAM,GPAT4,GPC1,GPT,GPT2,GRHPR,GSS,GSTA1,GSTM2,GSTO2,GSTP1,GSTZ1,HAAO,HACD1,HACD2,HACD3,HACD4,HACL1,HADHA,HADHB,HAO1,HAO2,HARS,HARS2,HDC,HEXA,HGD,HIBCH,HIF1A,HK3,HLCS,HMGCL,HNF4A,HNMT,HOGA1,HPD,HPGD,HPGDS,HPSE,HS3ST3B1,HS3ST4,HS3ST5,HS6ST1,HS6ST2,HS6ST3,HSD17B12,HSD17B4,HSD17B8,HSD3B7,HTD2,HYKK,IARS,IARS2,IDH2,IDH3A,IDH3G,IDNK,IDO1,IDO2,IDS,IDUA,IGF1,IL4I1,IMPAD1,IVD,IYD,KARS,KERA,KMO,KYAT1,KYNU,LARS,LARS2,LDHA,LDHAL6A,LDHAL6B,LDHB,LDHC,LEP,LGSN,LIPE,LIPF,LPIN1,LPIN3,LPL,LRAT,LTC4S,LUM,LYPLA1,LYPLA2,MAPK14,MAPK3,MAPKAPK2,MARC1,MARC2,MARS2,MCAT,MCCC1,MCCC2,MCEE,MDH1B,MDH2,ME1,ME2,ME3,MECP2,MECR,MGLL,MGST2,MGST3,MIF,MINPP1,MLYCD,MORC2,MPC1,MPC2,MPO,MPST,MRI1,MRS2,MSRA,MTAP,MTHFD1,MTHFD1L,MTHFD2,MTHFD2L,MTHFR,MTHFS,MTRR,MUT,NAALAD2,NAGK,NAGS,NARS,NARS2,NAT8L,NDNF,NDST1,NDST2,NDST3,NDST4,NDUFAB1,NFS1,NIT2,NMNAT3,NNT,NOS1,NOS2,NOS3,NOX4,NPC1,NPL,NR1H4,NR4A3,NR5A2,NUDT19,NUDT7,ODC1,OGDH,OGDHL,OGN,OLAH,OMD,OSBP,OSBPL2,OSBPL3,OSBPL9,OTC,OXSM,P4HA1,P4HB,PADI1,PADI2,PADI3,PADI4,PADI6,PAH,PAM,PANK2,PAPSS2,PARK7,PARP9,PARS2,PC,PCBD1,PCCB,PCK1,PCK2,PCYOX1,PCYOX1L,PDHA1,PDHA2,PDHB,PDHX,PDPN,PDXDC1,PDZD11,PECR,PEMT,PEPD,PER2,PEX13,PEX2,PEX7,PFKFB1,PFKFB2,PFKL,PFKP,PGAM1,PGAM2,PGAM4,PGD,PGK1,PGK2,PGM2L1,PHGDH,PHYH,PHYKPL,PKLR,PKM,PLA2G10,PLA2G15,PLA2G1B,PLA2G3,PLA2G4A,PLA2G4B,PLA2G4F,PLA2G5,PLOD2,PLP1,PM20D1,PNKD,PNPLA3,PODXL2,POLG2,POR,PPARA,PPARD,PPARG,PPARGC1A,PRDX4,PRELP,PRG3,PRKAA1,PRKAA2,PRKAB1,PRKAG2,PRKAG3,PRKAR2B,PRODH,PRODH2,PSAT1,PSPH,PTGDS,PTGES,PTGES2,PTGES3L-AARSD1,PTGIS,PTGR1,PTGR2,PTGS1,PTS,PYCR1,PYCR2,PYCR3,QDPR,QKI,QRSL1,RARS,RARS2,RBP1,RDH10,RENBP,RGN,RIMKLA,RIMKLB,SARDH,SARS,SARS2,SCD,SCLY,SCP2,SCPEP1,SDHA,SDHAF2,SDHAF3,SDHB,SDHD,SDHD,SDS,SDSL,SEPHS1,SEPSECS,SERINC3,SERINC5,SESN2,SGPL1,SGSH,SHMT1,SHMT2,SIRT4,SLC16A1,SLC16A8,SLC19A1,SLC1A3,SLC23A1,SLC23A2,SLC25A17,SLC25A21,SLC26A1,SLC26A2,SLC27A1,SLC27A2,SLC27A3,SLC27A4,SLC27A5,SLC27A6,SLC2A1,SLC2A3,SLC34A1,SLC35D1,SLC35D2,SLC46A1,SLC5A6,SLC6A14,SLC6A6,SLC6A8,SLC7A4,SLC7A5,SLC7A6,SLC7A7,SLC7A8,SMS,SNCA,SORD,SPOCK2,SPOCK3,SRD5A2,SRR,SSTR4,ST20-MTHFS,ST3GAL1,ST3GAL2,ST3GAL3,ST3GAL4,ST3GAL6,ST6GAL1,STAR,SUCLA2,SUCLG2,SULF2,SULT1A1,SULT1A2,SULT1A4,SULT1C2,SULT1C4,SULT2A1,SULT2B1,SULT4A1,SULT6B1,SUOX,SYK,TARS,TAT,TBXAS1,TDO2,TECR,TECRL,TH,THEM4,THEM5,THNSL2,TLR2,TNFRSF1A,TPH1,TPH2,TPST1,TPST2,TYMS,TYR,TYRP1,UCP3,UEVLD,UGT1A1,UGT1A10,UGT1A3,UGT1A4,UGT1A5,UGT1A6,UGT1A8,UGT1A9,UPB1,UROC1,UST,VANGL2,VCAN,VNN1,VNN2,VNN3,WARS,WARS2,XBP1,XYLT1,XYLT2,YARS,YARS2	TetrapodAncestor	99.7647
GO.Biological.Process	GO:0032989	cellular.component.morphogenesis	339	3.557960e-104	4.595817e-100	1.355698e-102	1.117649e+0	ABI1,ABL1,ACTN1,ADAM8,ADARB1,ADD1,ADGRB1,ADORA2A,AFG3L2,ALCAM,ALS2,ANK2,ANK3,ANKRD1,ANKRD27,ANOS1,ANTXR1,APBB2,APP,AR,ARC,ARHGAP35,ARHGEF2,ARHGEF26,ARL13B,ARTN,ARX,ASXL1,ATOH1,ATP8A2,AURKA,AUTS2,AXL,B3GNT2,BAX,BCL11B,BCL2,BCL2L1,BCL6,BDNF,BIN3,BMP10,BMP7,BMPR1B,BOC,BRSK1,BRSK2,BTBD3,BVES,C1GALT1C1,C21orf59,C9orf72,CABP4,CAMK2A,CAP1,CAP2,CASP3,CASP9,CASQ1,CASQ2,CCDC136,CCK,CCKAR,CD9,CDC42,CDH11,CDH4,CDK5,CDK5R1,CELSR2,CFL2,CFLAR,CHL1,CHRNB2,CIB1,CLDN3,CLEC1B,CLIC5,CLU,CNTN2,CNTN4,CNTNAP2,COBL,COL18A1,COL25A1,CREB1,CRMP1,CSF1R,CSNK1A1,CSRP3,CTNNA2,CTNNB1,CTNND2,CTTN,CUL3,CXCR4,CYFIP1,CYFIP2,DAB1,DAB2IP,DACT2,DBNL,DCC,DDR1,DKK1,DLG4,DLX5,DMRT1,DNM1L,DNM2,DOCK10,DOK1,DOK2,DOK4,DOK5,DOK6,DPYSL2,DPYSL4,DPYSL5,DRAXIN,DRD2,DSCAM,DSCAML1,DTNBP1,DVL1,DYNLT1,ECT2,EFNA1,EFNA3,EFNA4,EFNA5,EFNB1,EFNB2,EFNB3,EGFR,EGR2,EIF2AK4,EMX1,ENAH,ENSG00000173366,ENSG00000251246,ENSG00000265590,EP300,EPB41L3,EPB41L5,EPHA1,EPHA2,EPHA4,EPHA5,EPHA7,EPHA8,EPHB1,EPHB2,EPHB3,EPYC,ERBB2,ERCC2,ETV1,EVL,EXT1,EZR,FABP9,FAM129B,FARP1,FBXO45,FER,FERMT2,FERMT3,FEZ1,FEZ2,FEZF1,FGFR2,FHOD3,FIS1,FLNA,FLNB,FLOT1,FLRT1,FLRT2,FLRT3,FMN1,FN1,FOXG1,FRMD6,FRS2,FRY,FRYL,FZD3,FZD4,FZD7,GAB1,GAB2,GAP43,GATA3,GBX1,GBX2,GDNF,GFRA1,GFRA2,GFRA3,GFRA4,GJA1,GJE1,GLI2,GLI3,GP1BA,GP5,GPC1,GPM6A,GRB10,GRB2,GRB7,GREM1,GRHL2,HEG1,HES1,HGF,HPRT1,HRAS,HRH2,ID1,IGSF22,IHH,IL7R,IQGAP1,IRS2,ISL1,ISPD,ITGA1,ITGA4,ITGA8,ITGAV,ITGB1,ITGB7,KIF20B,KIF5A,KIF5B,KIF5C,KIRREL1,KIRREL3,KLF2,KLF7,KNL1,KRAS,KRT19,L1CAM,LAMA2,LAMA5,LAMB1,LAMC3,LATS1,LDB3,LEF1,LHFPL5,LHX1,LHX2,LHX4,LINGO1,LINGO4,LIPA,LLPH,LMOD1,LMOD3,LMX1A,LRFN1,LRFN2,LRFN4,LRP4,LRRC38,LRRC55,LRRC70,LRRK2,LRRN2,LST1,LYPLA2,MAEL,MAP1B,MAP1S,MAP2,MAP4K4,MAP6,MAP6D1,MAPK1,MAPK14,MAPK3,MATN1,MATN2,MEF2A,MEF2C,MERTK,MET,METTL3,MFF,MINK1,MSX1,MTM1,MTMR2,MYBPC1,MYBPC2,MYBPC3,MYBPH,MYH14,MYH3,MYH6,MYH9,MYLK3,MYOM2,MYOM3,MYOZ3,MYPN,NBEAL2,NBL1,NCAM1,NCMAP,NDEL1,NEBL,NECTIN1,NECTIN2,NEFH,NEFL,NEK3,NEO1,NES,NFASC,NFIB,NGF,NGFR,NKX2-5,NLGN3,NOG,NOTCH1,NOTCH4,NOX4,NPHS1,NPTX1,NR4A2,NR4A3,NRAS,NRG1,NRK,NRN1L,NRP1,NRP2,NRTN,NRXN1,NRXN3,NTF3,NTF4,NTN3,NTNG1,NTNG2,NTRK1,NUBPL,NUMB,NUMBL,NYAP1,NYAP2,OBSCN,OGN,OMG,OPA1,OPA3,OPHN1,OR10A4,OTX2,P2RX7,PACSIN2,PAFAH1B1,PAK1,PAK3,PALLD,PANK2,PARD3,PARD6B,PAX2,PDGFRB,PDLIM7,PDPN,PDZD7,PEAK1,PHOX2B,PICALM,PID1,PIK3CA,PIK3CD,PIK3R1,PIKFYVE,PITPNA,PLA2G10,PLA2G3,PLCG1,PLEKHO1,PLPPR4,PLXNA1,PLXNA2,PLXNA3,PLXNA4,PLXNB1,PNPT1,POF1B,POLDIP2,POLG2,POU4F1,POU4F3,PPP3CB,PRKAR1A,PRKCA,PRKCQ,PRKCZ,PROX1,PSPN,PTCH1,PTEN,PTK2,PTPN11,PTPRA,PTPRM,PTPRO,PTPRZ1,RAB1A,RAB25,RAB8A,RAC1,RADIL,RANBP9,RAP1GAP,RAPH1,RB1,RBFOX2,RELN,RERE,RET,RFX2,RILPL1,ROBO1,ROBO2,ROBO3,RPL24,RPS6KA5,RTN4R,RYK,S100A6,S100B,SCFD1,SCN1B,SCRIB,SDC2,SEC24B,SEMA3A,SEMA3C,SEMA4A,SEMA6A,SEMA6C,SEMA7A,SGK1,SH3GL2,SH3KBP1,SHANK1,SHC1,SHC3,SHROOM3,SIAH1,SIAH2,SIDT2,SIPA1L3,SLC1A3,SLC39A3,SLC9A3R1,SLIRP,SLIT1,SLIT2,SLIT3,SLITRK1,SLITRK2,SLITRK3,SLITRK4,SLITRK5,SLITRK6,SMAD4,SNX1,SNX2,SOD1,SOS1,SOX17,SPACA1,SPG11,SPON2,SPTB,SPTBN2,SPTBN5,SRC,SRCIN1,SRF,SRGAP2,SS18,SSBP1,ST14,STC1,STK24,STK26,STK4,STMN1,STRADB,STRC,STXBP1,SZT2,TAL1,TBC1D20,TBCD,TBPL1,TEK,TENM1,TENM2,TENM3,TENM4,TFCP2L1,TGFB2,THOC2,TIAM1,TLR2,TLR9,TMEM106B,TMEM108,TMOD1,TMOD2,TMOD3,TMOD4,TNFRSF8,TNMD,TNN,TNR,TRAK1,TRAK2,TRIM46,TSKU,TTN,TUBB3,TXNDC8,TYRO3,UCHL1,UGT8,ULK2,UNC5A,UNC5B,UNC5C,UNC5D,UPK3A,USP9X,VAMP3,VANGL2,VASP,VAX2,VCL,VDR,VEGFA,VLDLR,VSIG1,WASF2,WDR1,WNT3,WNT3A,WNT5A,WNT7A,WNT7B,YTHDF2,ZFPM1,ZNF335,ZNF365,ZNF385A,ZPBP2	TetrapodAncestor	99.3376
GO.Biological.Process	GO:0031061	negative.regulation.of.histone.methylation	340	4.585101e-104	5.922575e-100	1.741934e-102	1.947019e+0	BCOR,BRCA1,DNMT3B,H2AFY,JARID2,KDM3A,KDM4C,MECP2,MTF2,PAX5,PHF1,PIH1D1,SIRT1,SMARCB1	TetrapodAncestor	99.2275
GO.Biological.Process	GO:0030260	entry.into.host.cell	341	1.644810e-103	2.124601e-99	6.230502e-102	1.464043e+0	ACE2,ANPEP,AXL,CAV1,CAV2,CBL,CBLL1,CCR5,CD209,CD46,CD55,CD80,CD81,CD86,CDH1,CDHR3,CDK1,CLDN1,CLDN6,CLDN9,CLEC4G,CLEC4M,CR1,CR2,CTNNB1,CTNND1,CTSB,CXADR,CXCR4,DYNLT1,EFNB2,EFNB3,EGFR,EPHA2,EPS15,F11R,GAS6,GRB2,GRK2,HAVCR1,HTR2A,IDE,ITCH,ITGA2,ITGA5,ITGAV,ITGB1,ITGB5,ITGB7,KPNA3,LDLR,MET,MRC1,NCAM1,NECTIN1,NECTIN2,NECTIN4,NPC1,NUP153,RPS27A,RPSA,SCARB1,SCARB2,SERPINB3,SLC10A1,SLC1A5,SLC52A1,SLC52A2,SRC,TFRC,TNFRSF14,TNFRSF4,TYRO3,UBC,UVRAG,VAMP8,VPS18,WWP1,WWP2,XPR1,ZNF639	TetrapodAncestor	98.6727
GO.Biological.Process	GO:0090162	establishment.of.epithelial.cell.polarity	342	1.991391e-103	2.572280e-99	7.521286e-102	1.669132e+0	ARF6,CAMSAP3,CDC42,CLASP1,CYTH1,CYTH3,FBF1,FERMT1,FOXF1,FRMD4A,FRMD4B,GOLPH3,HES1,HES5,MSN,MYO18A,MYO9A,OPHN1,PARD3,PTK7,SH3BP1,SIPA1L3,SLC9A3R1,SYNE4,TCF15,WNT5A	TetrapodAncestor	98.5897
GO.Biological.Process	GO:0048598	embryonic.morphogenesis	343	2.829946e-103	3.655441e-99	1.065726e-101	1.137226e+0	ABL1,ABR,ACD,ACVR2A,ACVR2B,AFF3,AHI1,ALDH1A3,ALX1,ALX4,AMOT,APAF1,APELA,APLNR,ARHGAP35,ARID1A,ARL13B,ATOH1,ATOH8,ATP6V1B1,ATP8A2,B9D1,BAX,BBS4,BBS7,BCL10,BCL2L11,BCR,BMP4,BMP5,BMP7,BMPR1A,BMPR2,C2CD3,C2orf49,C5orf42,CACNA1C,CCDC103,CCDC40,CDC73,CDKN1C,CDON,CELSR1,CER1,CFL1,CHD7,CHRD,CHRNA10,CHRNA9,CHST11,CLIC5,COBL,COL11A1,COL12A1,COL2A1,COL6A1,COL7A1,COL8A1,CRABP2,CRB2,CTNNB1,CUL3,CYP26B1,CYR61,DACT1,DCANP1,DEAF1,DKK1,DLC1,DLD,DLG1,DLL1,DLL4,DLX5,DNAAF1,DNAJB6,DSCAML1,DUSP1,DUSP2,DVL1,DVL3,DYNC2H1,EDN1,EFEMP1,EFNA1,EGF,EIF4A3,ELF5,EN1,ENG,EOMES,EPB41L5,EPHA2,EPHB2,ETS2,EXOC4,EXT1,EXT2,EYA1,EYA2,FBN2,FGF10,FGF2,FGF4,FGF9,FGFR1,FGFR2,FLRT3,FLT1,FLVCR1,FN1,FOXA2,FOXC1,FOXC2,FOXE1,FOXF1,FOXF2,FOXG1,FOXH1,FOXI1,FOXN4,FRAS1,FRS2,FUZ,FZD1,FZD2,FZD3,FZD5,FZD6,GATA2,GATA3,GATA4,GATA6,GBX2,GDF3,GDF5,GDNF,GJB5,GLI2,GLI3,GNA12,GNAQ,GNAS,GPC3,GRB2,GREM1,GREM2,GRHL2,GRHL3,GRSF1,GSC,HAND1,HAND2,HDAC1,HDAC2,HES1,HES3,HES5,HESX1,HHEX,HIF1A,HIPK1,HIPK2,HIRA,HLX,HMGA2,HNF1B,HOXA1,HPN,HSBP1,HTR2B,ID2,IFT140,IFT172,IFT52,IFT57,IGF2,IHH,IL10,IMPAD1,INHBA,INSIG2,INTU,ITGA2,ITGA3,ITGA4,ITGA5,ITGA7,ITGA8,ITGAV,ITGB1,ITGB2,ITGB4,ITGB5,JAG2,KCNQ4,KDF1,KDM2B,KDM6A,KDM6B,KIF16B,KIF20B,KLF4,LAMA3,LAMA5,LAMB1,LAMB3,LATS1,LBX1,LEF1,LEO1,LHFPL5,LHX1,LHX2,LMO4,LRIG1,LRIG3,LRP4,LRP5,LRP6,LUZP1,MAFB,MAPK1,MAPK3,MBNL1,MDFI,MEF2C,MEGF8,MESP1,MESP2,MFAP2,MIB1,MIXL1,MKKS,MKS1,MMP14,MMP15,MMP16,MMP8,MMP9,MSGN1,MSX1,MSX2,MTHFD1,MTHFD1L,MYCN,MYH3,NANOG,NCOA1,NDRG4,NDST1,NEUROD1,NEUROG1,NF2,NIPBL,NKX2-5,NKX3-2,NOG,NOTCH1,NOTO,NPHP3,NR4A3,OSR1,OTX1,OTX2,OVOL2,PAF1,PAX2,PAX5,PAX8,PBX1,PBX2,PCDH8,PCGF2,PDZD7,PFN1,PHACTR4,PITX1,PITX2,PKD2,PLXNB2,POFUT2,POGLUT1,POU3F4,POU4F3,PRICKLE1,PRKACA,PRKAR1A,PRKRA,PROX1,PRRX1,PSEN1,PTCH1,PTK7,RALA,RARA,RARB,RARG,RBP4,RBPMS2,RDH10,RECK,RET,RIC8A,RNF2,ROR2,RPL38,RPS6,RSPO2,RSPO3,RTF1,RUNX2,RYR2,SATB2,SCRIB,SCX,SDC4,SEC24B,SEMA4C,SETD2,SETDB2,SFRP1,SFRP2,SHOX2,SHROOM3,SIX2,SKI,SLC39A3,SLC9A3R1,SLITRK6,SMAD2,SMAD4,SMO,SNAI1,SOBP,SOCS3,SOD1,SOS1,SOX11,SOX17,SOX18,SOX2,SOX4,SOX7,SOX8,SOX9,SP8,SPINT1,SPRY2,SRF,ST14,STIL,STK4,STRA6,STRC,SUFU,T,TAL1,TBC1D32,TBX1,TBX15,TBX2,TBX20,TBX3,TBX5,TBX6,TCF21,TEAD2,TENM4,TFAP2A,TGFB1,TGFB1I1,TGFB2,TGFBR1,TGFBR2,TH,TIFAB,TLX2,TMED2,TMEM107,TMEM231,TMIE,TP63,TRAF3IP1,TRAF6,TRIM28,TRIM71,TSC2,TULP3,TWIST1,TXNRD1,USH1C,USH1G,VANGL2,VASP,VAX2,VEGFC,VTN,WDR60,WLS,WNT1,WNT11,WNT16,WNT3,WNT3A,WNT4,WNT5A,WNT6,WNT7A,WNT7B,WNT8B,WNT9A,WNT9B,YTHDF2,ZBTB16,ZBTB17,ZEB1,ZFP36L1,ZIC1,ZIC3,ZNF281,ZNF358	TetrapodAncestor	98.4371
GO.Biological.Process	GO:0014743	regulation.of.muscle.hypertrophy	344	3.937894e-103	5.086578e-99	1.478656e-101	1.484643e+0	AGT,AKAP13,AKAP6,ATP2B4,BMP10,CAMK2D,CAV3,CDK9,CTDP1,EDN1,ERRFI1,FOXO1,G6PD,GLRX3,GSK3A,HAMP,HAND2,IGF1,IGFBP5,IL6ST,JARID2,LMCD1,LMNA,MEF2A,MLIP,MSTN,MTOR,MTPN,NR4A3,P2RX4,PAK1,PARP1,PDE5A,PDE9A,PIN1,PPP3CA,PRKCA,RGS2,SLC9A1,SMAD4,TRIM63,TRPC3,TWF1	TetrapodAncestor	98.2936
GO.Biological.Process	GO:1903670	regulation.of.sprouting.angiogenesis	345	4.298157e-103	5.551929e-99	1.609255e-101	1.598575e+0	ABL1,ADAMTS9,CIB1,DLL1,DLL4,FGF1,FGF2,FOXC2,GHSR,HDAC5,HDAC7,HDAC9,HMGB1,ITGA5,JCAD,KLF4,MEOX2,MMRN2,NGFR,NOTCH1,NRP1,PDCD10,PPP1R16B,SPRED1,SRPX2,STARD13,SYNJ2BP,TMEM2,VEGFA	TetrapodAncestor	98.2556
GO.Biological.Process	GO:0002274	myeloid.leukocyte.activation	346	4.840834e-103	6.252905e-99	1.807198e-101	1.201178e+0	A1BG,ABCA13,ACPP,ACTR10,ACTR2,ADA2,ADAM8,ADAM9,ADGRE3,ADGRE5,ADGRG3,AGA,AGL,AGPAT2,AHSG,AIF1,ALAD,ALDH3B1,ALDOA,ALOX5,ANO6,ANPEP,ANXA3,AOC1,AP1M1,AP2A2,APAF1,APEH,ARG1,ARL8A,ARPC5,ASAH1,ATAD3B,ATP11A,ATP11B,ATP6AP2,ATP6V0C,ATP6V1D,ATP8A1,ATP8B4,B4GALT1,BATF2,BATF3,BPI,BST1,BST2,BTK,C16orf62,C1orf35,C3,C3AR1,C6orf120,CAB39,CALML5,CAMK4,CAND1,CANT1,CAP1,CAPN1,CAT,CBL,CCL3,CCL5,CCT2,CCT8,CD14,CD300A,CD33,CD36,CD44,CD47,CD53,CD55,CD58,CD59,CD63,CD68,CD86,CD93,CDA,CDK13,CFP,CHGA,CHI3L1,CHIT1,CHRNB4,CKAP4,CLEC12A,CLEC4C,CLEC4D,CLU,CMTM6,COMMD3,COMMD9,COTL1,CPLX2,CPNE3,CPPED1,CR1,CRACR2A,CREG1,CRISP3,CRISPLD2,CRTC3,CSF1,CSNK2B,CSTB,CTSA,CTSB,CTSC,CTSD,CTSH,CTSZ,CX3CR1,CXCL1,CXCL6,CXCL8,CXCR1,CXCR2,CYB5R3,CYBA,CYBB,CYFIP1,CYSTM1,DBNL,DDOST,DDX3X,DEGS1,DERA,DGAT1,DHRS2,DIAPH1,DNAJC13,DNASE1L1,DOCK2,DOK3,DPP7,DSC1,DSG1,DSN1,DSP,DYNC1H1,DYNC1LI1,DYNLL1,DYNLT1,EDN2,EEF1A1,EEF2,ENPP4,EPX,F2RL1,FABP5,FAF2,FCAR,FCER1G,FCN1,FGL2,FGR,FLG2,FRK,FRMPD3,FTH1,FTL,FUCA1,FUCA2,GAA,GDI2,GGH,GLA,GLB1,GLIPR1,GM2A,GMFG,GNS,GOLGA7,GPR84,GRN,GSDMD,GSN,GSTP1,GUSB,GYG1,HAVCR2,HBB,HEBP2,HK3,HMGB1,HMOX2,HP,HPSE,HRNR,HSP90AB1,HSPA8,IFNB1,IGF2R,IL13,IL18,IL18RAP,IL33,IL4,ILF2,IMPDH1,IQGAP1,IRF4,IST1,ITGAM,ITGAV,ITGAX,ITGB2,JMJD6,JUN,JUP,KARS,KCNAB2,KMT2E,KPNB1,KRT1,LAIR1,LAMTOR2,LAMTOR3,LAT,LAT2,LBP,LCN2,LCP2,LGALS3,LILRB2,LRG1,LRMP,LRRC7,LTBR,LYN,LYZ,MAN2B1,MANBA,MAPK1,MAPK14,MAPT,MCEMP1,MGAM,MGST1,MIF,MILR1,MLEC,MME,MMP25,MMP8,MMP9,MOSPD2,MPO,MS4A3,MVP,NAPRT,NBEAL2,NCKAP1L,NCSTN,NDRG1,NDUFC2,NFAM1,NFASC,NFKB1,NHLRC3,NIT2,NME2,NPC2,NR4A3,NRAS,OLFM4,OLR1,ORM1,ORM2,ORMDL3,OSCAR,OSTF1,PADI2,PAFAH1B2,PDAP1,PDXK,PECAM1,PFKL,PGAM1,PGLYRP1,PGM2,PGRMC1,PIGR,PIK3CD,PIK3CG,PKM,PKP1,PLA2G3,PLAC8,PLAU,PLD1,PLEKHO2,PNP,PPBP,PPIE,PRCP,PRDX4,PREX1,PRG2,PRG3,PRKCD,PRKCE,PRSS2,PRSS3,PSAP,PSEN1,PSMA2,PSMB1,PSMB7,PSMC2,PSMC3,PSMD1,PSMD11,PSMD13,PSMD2,PSMD3,PSMD7,PTAFR,PTGES2,PTPRB,PTPRJ,PTPRN2,PTX3,PYCARD,PYGB,QPCT,QSOX1,RAB14,RAB18,RAB24,RAB27A,RAB31,RAB37,RAB3D,RAB44,RAB4B,RAB5B,RAB6A,RAB7A,RAB9B,RAC1,RAP1A,RAP1B,RAP2B,RAP2C,RASGRP1,RBPJ,RELB,RETN,RHOG,RNASET2,S100A11,S100A12,S100A13,S100A7,S100A8,S100A9,S100P,SDCBP,SELL,SERPINA1,SERPINA3,SERPINB1,SERPINB10,SERPINB12,SERPINB3,SERPINB6,SIGLEC9,SIRPA,SIRPB1,SLC11A1,SLC15A4,SLC27A2,SLC2A3,SLC44A2,SLCO4C1,SLPI,SNAP23,SNAP25,SNAP29,SNCA,SPACA3,SPI1,SRP14,STBD1,STK11IP,STOM,STXBP2,SURF4,SVIP,SYK,SYNGR1,TARM1,TBC1D10C,TCIRG1,TCN1,TGFB1,TGFBR2,TICAM1,TICAM2,TIMP2,TLR1,TLR2,TLR3,TLR4,TLR6,TMBIM1,TMC6,TMEM173,TMEM63A,TNFAIP6,TNFRSF1B,TOLLIP,TOM1,TRAF6,TRAPPC1,TRPM2,TRPV1,TTR,TUBB,TUBB4B,TXNDC5,UBR4,VAMP2,VAMP8,VAPA,VAT1,VCL,VCP,VNN1,XRCC5,XRCC6,YPEL5	TetrapodAncestor	98.2039
GO.Biological.Process	GO:0006986	response.to.unfolded.protein	347	1.586657e-102	2.049485e-98	5.906296e-101	1.406356e+0	ACADVL,ADD1,AMFR,ASNA1,ASNS,ATF3,ATF4,ATF6,ATF6B,ATP6V0D1,BAK1,BAX,BHLHA15,CALR,CCL2,CCND1,CHAC1,CREB3,CREB3L1,CREB3L2,CREB3L3,CREBRF,CTDSP2,CTH,CUL7,CXCL8,CXXC1,DAB2IP,DAXX,DCTN1,DDX11,DERL1,DERL2,DERL3,DNAJA1,DNAJB1,DNAJB11,DNAJB5,DNAJC4,DZIP3,EDEM1,EDEM2,EDEM3,EIF2AK2,EIF2AK3,EP300,ERN1,ERO1A,EXTL1,EXTL2,EXTL3,FAF2,FBXO6,FGF21,FKBP14,GFPT1,GOSR2,GSK3A,HDGF,HERPUD1,HERPUD2,HSF1,HSP90AB1,HSP90B1,HSPA2,HSPA4,HSPA4L,HSPA5,HSPA8,HSPB1,HSPB2,HSPB3,HSPB7,HSPH1,HYOU1,IFNG,JKAMP,KDELR3,KLHDC3,LMNA,MANF,MBTPS1,MBTPS2,MFN2,MYDGF,OPTN,PACRG,PARP16,PDIA6,PLA2G4B,PPP1R15A,PPP2R5B,PREB,PRKN,PTPN1,RHBDD1,RNF121,RNF175,SEC61A1,SEC61A2,SEC61B,SEC61G,SEC62,SEC63,SERP1,SERP2,SERPINH1,SHC1,SRPRA,SRPRB,SSR1,STC2,STT3B,STUB1,SYVN1,TBL2,THBS1,THBS4,TLN1,TM7SF3,TMBIM6,TMEM129,TOR1B,TPP1,UBE2J2,UBXN4,UGGT1,VAPB,VCP,WFS1,WIPI1,XBP1,YOD1,ZBTB17	TetrapodAncestor	97.6884
GO.Biological.Process	GO:0045661	regulation.of.myoblast.differentiation	348	2.437450e-102	3.148454e-98	9.047282e-101	1.509249e+0	ANKRD2,BMP4,BOC,BTG1,CCL17,CDON,CMTM5,CXCL10,CXCL14,CXCL9,DLL1,EID2B,FLOT2,FLT3LG,GDF3,HIF1AN,ID3,IL18,MAP3K5,MAPK14,MBNL3,MEF2C,MSTN,MYF6,MYOCD,MYOD1,MYOG,NMRK2,NOTCH1,PLCB1,PPARD,PRICKLE1,RANBP3L,RIPOR2,SMYD1,SOSTDC1,SOX8,SOX9,TBX3,TGFB1,TNF,TNFSF14,TRIP4,ZFP36L1	TetrapodAncestor	97.5019
GO.Biological.Process	GO:0048705	skeletal.system.morphogenesis	349	2.550005e-102	3.293841e-98	9.437941e-101	1.232596e+0	ACP5,ACVR2B,ALPL,ALX1,ALX4,ARID5B,AXIN2,BARX2,BMP1,BMP4,BMP6,BMP7,BMPR1B,BMPR2,CARM1,CDX1,CER1,CHST11,COL10A1,COL11A1,COL13A1,COL1A1,COL27A1,COL2A1,CSGALNACT1,CSRNP1,CTGF,CTNNB1,CYP26B1,DCANP1,DHRS3,DLG1,DLX5,DSCAML1,EIF4A3,EYA1,FBN2,FGF18,FGF4,FGF6,FGFR1,FGFR2,FGFR3,FLVCR1,FMN1,FOXC1,FOXC2,FOXN3,FREM1,FUZ,GLG1,GLI3,GNAS,GRHL2,GSC,HAS2,HOXA1,IFITM5,IFT140,IHH,IMPAD1,INSIG2,LHX1,LRP5,MAPK14,MATN1,MDFI,MEF2C,MEF2D,MEGF8,MGP,MMP13,MMP14,MMP16,MSX1,MSX2,MTHFD1,MTHFD1L,MYCN,NAB2,NDST1,NEUROG1,NIPBL,NKX3-2,NLE1,NOG,NPPC,OSR1,OTOR,P2RX7,PAPPA2,PAX5,PCGF2,PEX7,PHOSPHO1,PKD1,PLEKHA1,POC1A,PPARGC1B,PRKRA,PRRX1,PSEN1,RAB23,RAB33B,RARA,RARB,RARG,RDH10,RFLNB,RIPPLY1,RIPPLY2,ROR2,RUNX2,SATB2,SCX,SERPINH1,SETD2,SFRP1,SFRP2,SFRP4,SGPL1,SHOX2,SIX2,SKI,SLC39A3,SMAD2,SOX11,SOX9,STC1,T,TBX1,TBX15,TCF15,TEK,TFAP2A,TGFB1,TGFBR1,TGFBR2,THBS3,THRA,TIFAB,TIPARP,TRIP11,TULP3,TWIST1,WDR60,WNT10B,WNT7A,WNT9A,WNT9B,WWOX,ZEB1,ZFAND5	TetrapodAncestor	97.4823
GO.Biological.Process	GO:0031589	cell-substrate.adhesion	350	3.314605e-102	4.281475e-98	1.223279e-100	1.314396e+0	ABL1,ACTN1,ADAM15,ADAM9,ADAMTS12,ADAMTS13,ADAMTS9,AJUBA,ANGPT1,ANTXR1,ARHGAP6,ARHGEF7,AXL,BCAM,BCL2,BCL2L11,BVES,CCL21,CD34,CD44,CD63,CD96,CDK5,COL13A1,COL3A1,COL5A3,CORO1A,CTGF,CTNNB1,CTTN,CUZD1,DDR1,DLC1,ECM2,EDA,EFNA1,EMILIN1,EMP2,ENSG00000259753,EPB41L5,EPDR1,EPHA1,EPHB1,EPHB3,FBLN5,FER,FERMT2,FERMT3,FGG,FN1,FREM1,FZD4,FZD7,GAS6,HPSE,ID1,ITGA1,ITGA10,ITGA11,ITGA2,ITGA2B,ITGA3,ITGA4,ITGA5,ITGA7,ITGA8,ITGAV,ITGB1,ITGB2,ITGB4,ITGB5,ITGB7,JAM3,L1CAM,LAMA5,LAMB1,LYPD3,MADCAM1,MERTK,MKLN1,MSLN,MSLNL,MUC4,MYO1G,NID2,NRP1,OTOA,PARVG,PDPK1,PEAK1,PIP5K1A,PKD1,PPARD,PPFIA1,PPFIA2,PRKX,PTK2B,PTPRK,PXN,RAB1A,RAC1,RADIL,RCC2,RHOD,SIGLEC1,SNED1,SORBS1,SORBS3,SRC,SRCIN1,SRF,SRGAP2,STRC,TAOK2,TECTA,TEK,TESK2,THBS3,THY1,TIAM1,TMEM8B,TNFRSF12A,TNN,TRIP6,TRPM7,TTYH1,TYRO3,VAMP3,VCAM1,VCL,VTN,VWA2,VWF,ZYX	TetrapodAncestor	97.3684
GO.Biological.Process	GO:1903707	negative.regulation.of.hemopoiesis	351	5.485132e-102	7.085145e-98	2.018560e-100	1.341859e+0	ADIPOQ,ANXA1,BCL6,BMP4,C1QC,CARTPT,CCL3,CD74,CDC73,CDK6,CIB1,CLDN18,CTLA4,CTNNB1,CUL4A,DLL1,DTX1,ERBB2,FBXO7,FOXJ1,FOXP3,FSTL3,GABPA,GATA2,GLI3,GPR171,GPR55,GPR68,HES1,HES5,HIST1H4J,HIST1H4K,HIST1H4L,HIST2H4B,HIST4H4,HLX,HMGB1,HMGB3,HSPA9,IFNA2,IFNB1,IFNL1,IHH,IL2,IL4,INHA,INHBA,INPP5D,IRF1,ITPKB,JAK3,KLF13,LEO1,LILRB4,LOXL3,LRRC17,LYN,MAFB,MEIS1,MEIS2,MIXL1,MYC,NF1,NFKBID,NME1,NME2,NOTCH1,PAF1,PF4,PGLYRP1,PGLYRP2,PGLYRP3,PIK3R1,PRMT1,PTK2B,RARA,RC3H1,SFRP1,SMAD7,SOCS5,TJP2,TLR3,TLR4,TMEM131L,TMEM176A,TMEM176B,TMEM178A,TNFSF18,TRIB1,UBASH3B,WDR61,ZBTB16,ZC3H8,ZFP36,ZFP36L1,ZFPM1,ZNF675	TetrapodAncestor	97.1497
GO.Biological.Process	GO:0030308	negative.regulation.of.cell.growth	352	2.031841e-101	2.624529e-97	7.456048e-100	1.301663e+0	ACVR1B,ACVRL1,ADAM15,ADIPOR1,ADIPOR2,AGT,AGTR2,APBB2,ARHGAP4,BCL11A,BCL2,BCL6,BDKRB1,BMP10,BMPR2,BST2,BTG1,CAPRIN2,CAV3,CCAR2,CCDC85B,CDA,CDHR2,CDK5,CDK5R1,CDKN1A,CDKN1B,CDKN2A,CDKN2AIP,CDKN2C,CDKN2D,CRLF3,CRYAB,CTDP1,CYP27B1,DACT3,DCBLD2,DCC,DCUN1D3,DDX3X,DRAXIN,EI24,ENPP1,EPHA7,ESR2,FBP1,FGF13,FLCN,FSTL4,G6PD,GAL,GDF2,GJA1,GREM1,GSK3A,HNF4A,HRG,IFRD1,INHBA,JADE1,MAG,MSX1,MUL1,NAIF1,NDRG3,NDUFS3,NOV,NPR1,NRP1,OSGIN1,OSGIN2,OSTN,PAK1,PHB,PLXNA3,PML,PPARD,PPARG,PPP1R9B,PPT1,PTPRJ,PTPRS,RBBP7,RERG,RNF6,RTN4,RTN4R,SCGB3A1,SEMA3A,SEMA3G,SEMA5A,SERPINE2,SERTAD2,SESN2,SFRP1,SFRP2,SH3BP4,SIPA1,SIRT1,SLIT2,SLIT3,SMAD4,SMARCA2,SMARCA4,SOX17,SPP1,ST7L,TGFB1,TGFB2,TNR,TP53,TP53TG5,TRO,ULK2,WFDC1,WNT11,WNT3,WNT3A,WNT5A	TetrapodAncestor	96.5809
GO.Biological.Process	GO:0060070	canonical.Wnt.signaling.pathway	353	3.972293e-101	5.131011e-97	1.453544e-99	1.341757e+0	AMER1,APC,BCL9,BCL9L,CAV1,CCND1,CDC42,CDH3,CHD8,CSNK1A1,CTNNB1,DISC1,DIXDC1,DVL1,DVL3,EGF,FRAT1,FRAT2,FZD1,FZD10,FZD2,FZD3,FZD4,FZD5,FZD7,FZD8,FZD9,GATA3,KDM6A,KLF4,LEF1,LGR4,LRP5,LRP6,LRRK2,MYC,NDP,NKX2-5,NR4A2,OTULIN,PLPP3,PPP1CA,PROP1,PSEN1,PTEN,PTK7,PTPRU,PYGO2,RAB5A,RARG,RYK,RYR2,SCYL2,SFRP1,SNAI2,SOX17,SOX4,T,TBL1X,TBL1XR1,TCF7L1,TMEM64,WNT1,WNT10A,WNT10B,WNT11,WNT3,WNT3A,WNT4,WNT5A,WNT7A,WNT7B,WNT8A,WNT8B,WNT9A,WNT9B,ZNRF3	TetrapodAncestor	96.2898
GO.Biological.Process	GO:0031349	positive.regulation.of.defense.response	354	4.263840e-101	5.507602e-97	1.555820e-99	1.218556e+0	ADAM8,ADORA2B,AGT,AGTR1,ANKRD17,AP1G1,APOB,ARG1,BCL10,BIRC2,BIRC3,BTK,BTRC,C3,CADM1,CARD11,CASP8,CCL3,CCL5,CCR2,CCR7,CD14,CD180,CD1D,CD209,CD226,CD28,CD300LF,CD36,CD47,CD6,CD86,CDK19,CHUK,CLEC4A,CLEC4C,CLEC4D,CLEC4E,CLEC6A,CLEC7A,CNPY3,CNR1,COLEC12,CREB3L3,CRTAM,CTSB,CTSL,CUL1,CX3CL1,CYBA,DDT,DDX58,DDX60,DHX9,DMBT1,EGFR,ENSG00000173366,EP300,EREG,ETS1,F12,F2RL1,FABP4,FADD,FBXW11,FCER1G,FCN1,FFAR2,FFAR3,FGG,GJA1,GPRC5B,GPSM3,HAVCR2,HCK,HEXIM1,HMGB1,HMGB2,HRAS,HSP90B1,ICAM2,IDO1,IFNB1,IFNK,IKBKB,IKBKE,IKBKG,IL12A,IL12B,IL15,IL17A,IL17B,IL17F,IL17RA,IL17RB,IL17RC,IL18,IL18RAP,IL1B,IL1RL1,IL2,IL21,IL23A,IL33,IL6,IL6ST,INAVA,IRAK1,IRAK3,IRAK4,IRF3,IRF7,IRGM,ITCH,ITGA2,ITGAM,ITGB2,JAK2,KARS,KLKB1,KLRK1,KRAS,LBP,LDLR,LGMN,LPL,LRRC70,LRSAM1,LY96,LYN,MALT1,MAP2K6,MAP3K1,MAP3K7,MAPK13,MAPK3,MAPKAPK2,MAPKAPK3,MARCO,MATR3,MB21D1,MEF2C,MGST2,MMP12,MUC1,MUC12,MUC13,MUC15,MUC20,MUC3A,MUC4,MUC5AC,MUC5B,MUC6,MUCL1,NCR3,NECTIN2,NFKB1,NLRC4,NLRC5,NLRP10,NOD1,NPY5R,NR1H4,NRAS,OPTN,OSM,OSMR,OTULIN,PAK1,PAK2,PAK3,PARK7,PARP9,PDE2A,PDPK1,PENK,PGC,PGLYRP1,PGLYRP2,PGLYRP3,PGLYRP4,PIK3AP1,PIK3C3,PIK3CG,PLA2G2A,PLA2G7,PLCG2,PLSCR1,POLR3B,POLR3C,POLR3D,POLR3F,PQBP1,PRKACA,PRKACG,PRKCD,PRKCE,PRKDC,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PSPC1,PTGER3,PTGER4,PYCARD,RAF1,RASGRP1,RBM14,REG3G,RELA,RELB,RFTN1,RIOK3,RIPK1,RIPK2,RPS27A,RPS6KA3,RPS6KA5,S100A1,S100A12,S100A14,S100A8,S100A9,SFPQ,SH2D1A,SH2D1B,SLAMF6,SLC25A6,SNAI3,SNCA,SNX4,SRC,SYK,TAB1,TAB2,TAB3,TAC1,TBK1,TGFB1,TGM2,TICAM1,TICAM2,TIRAP,TLR1,TLR10,TLR2,TLR3,TLR4,TLR5,TLR6,TLR9,TMEM173,TMEM189-UBE2V1,TNF,TNFAIP3,TNFRSF11A,TNFRSF1A,TNFSF11,TNFSF18,TNIP1,TNIP2,TNIP3,TRAF3,TRAF6,TRIL,TRIM5,TRIM6,TXK,UBC,UBE2D1,UBE2D2,UBE2D3,UBE2N,UCN,UNC13B,UNC93B1,VAMP8,VAV1,WNT5A,XRCC5,XRCC6,ZP3	TetrapodAncestor	96.259
GO.Biological.Process	GO:0034333	adherens.junction.assembly	355	4.786480e-101	6.182696e-97	1.741605e-99	1.694343e+0	ACTN1,AJUBA,ARHGAP6,ARHGEF7,BCL2,CTNNB1,CTTN,DLC1,DLG5,FERMT2,HIPK1,ITGA2,JUP,LAMA5,PDPK1,PIP5K1A,PIP5K1C,PTK2B,PTPRK,RAMP2,RCC2,RHOD,SMAD7,SORBS1,TAOK2,TBCD,TESK2,THY1,TRIP6,VCL,ZNF703	TetrapodAncestor	96.2088
GO.Biological.Process	GO:0010717	regulation.of.epithelial.to.mesenchymal.transition	356	8.527084e-101	1.101443e-96	3.093942e-99	1.348498e+0	ADIPOR1,ALX1,AXIN2,BAMBI,BCL9L,BMP2,BMP4,BMP5,BMP7,CLASP1,CLASP2,COL1A1,CRB2,CTNNB1,DAB2,DAB2IP,DACT3,EFNA1,ELL3,ENG,EPB41L5,EPHA3,EZH2,FOXA1,FOXA2,FOXC1,FUZ,GCNT2,GLIPR2,GREM1,HDAC2,HPN,IL1B,ISL1,LDLRAD4,LEF1,MAD2L2,MCRIP1,MTOR,NOG,NOTCH1,OLFM1,OVOL2,PBLD,PDPN,PHLDB1,PHLDB2,POFUT2,PTEN,RGCC,SDCBP,SDHAF2,SERPINB3,SFRP1,SFRP2,SMAD2,SMAD4,SMAD7,SNAI1,STRAP,TBX5,TGFB1,TGFB1I1,TGFB2,TGFBR1,TGFBR2,TIAM1,TRIM62,TWIST1,WWTR1,ZNF703	TetrapodAncestor	95.958
GO.Biological.Process	GO:1904951	positive.regulation.of.establishment.of.protein.localization	357	8.584357e-101	1.108841e-96	3.105998e-99	1.176418e+0	AACS,ABAT,ABL1,ABLIM3,ACHE,ACSL3,ACSM6,ADAM8,ADAM9,ADORA2A,AGER,AGTR2,AKT2,ALOX15B,ANK3,ANKRD1,ANO1,APP,ARF1,ARRB1,ATG13,ATP13A2,B3GAT3,BAD,BAMBI,BAP1,BCAP31,BCAS3,BCL2,BCL2L11,BID,BLK,BMP4,BMP6,BMPR1A,C1QTNF12,C1QTNF3,C2CD2L,C2CD5,C5,C8orf4,CADM1,CAMK1,CAPN10,CASP1,CASP5,CASP8,CASR,CCL19,CCL2,CCL3,CCT2,CCT4,CCT5,CCT6A,CCT7,CCT8,CD14,CD2,CD27,CD274,CD34,CD38,CD58,CDC42,CDH1,CDK1,CDK5,CDK5R1,CDKL2,CEMIP,CFTR,CHERP,CHIA,CHP1,CHRM1,CHUK,CIB1,CLEC4E,CLEC6A,CLEC9A,CNST,CRTAM,CSF1R,CSF3,CSNK2A2,CTDSPL2,CYB5R1,DAB2,DACT1,DDX58,DHX9,DKC1,DMAP1,DNM1L,DOC2B,DRD2,DTWD2,DYNLL1,DYNLL2,E2F1,ECT2,EDA,EDAR,EDEM1,EDEM2,EGF,EGFR,ELMOD1,ERBB2,ERBB4,EXPH5,EZR,F2,F2R,F2RL1,FAM20B,FBXW7,FCN1,FERMT1,FFAR1,FFAR2,FGG,FGR,FIS1,FLNA,FZD5,GAPDH,GAS6,GATA3,GCK,GIP,GIPR,GJA1,GLI3,GLUD1,GLUL,GOLPH3,GPER1,GPHA2,GPLD1,GPR68,GREM1,GSDMD,GSK3A,GTSE1,HAVCR2,HCLS1,HDAC3,HES1,HHAT,HIF1A,HMGB1,HMHB1,HNMT,HPCA,HPS4,HSP90AB1,HTR2B,HTRA2,ICE1,IFNAR1,IFNG,IFNL3,IGF1,IL10,IL12B,IL13,IL17A,IL17F,IL17RA,IL17RB,IL17RC,IL18,IL18R1,IL1A,IL1B,IL1RAP,IL1RL1,IL2,IL23A,IL26,IL33,IL5,IL6,INS,IPO5,IRF3,IRS2,ISL1,ITGAM,ITGAX,JAK2,JUP,KANK1,KARS,KCNB1,KCNN3,KIF20B,KIF5B,LACRT,LEP,LEPROT,LGALS9,LPL,LRP1,LRRK2,MAPK1,MAPK11,MAPK14,MAPK3,MAPK8,MCU,MDM2,MFF,MIEF1,MIEF2,MIF,MIS18A,MMP12,MPC2,MRGPRE,MYBPC1,MYO18A,MYO1C,MYRIP,NKX6-1,NLRP1,NLRP10,NLRP2,NMT1,NMUR1,NNAT,NPEPPS,NR0B2,NR1H2,NR1H4,NRG1,NUTF2,OAZ1,OAZ2,OR51E2,ORM1,ORM2,OXCT1,P2RX7,PAEP,PAK1,PANX1,PARP1,PCK2,PCM1,PCNT,PDCD10,PDCD5,PEMT,PFKFB2,PHPT1,PIK3R1,PIK3R2,PINK1,PLA2G1B,PLA2G6,PLK3,PMAIP1,POLR3A,PPARD,PPP1R13B,PPP3CA,PPP3CB,PPP3CC,PPP3R1,PRELID3A,PRKACA,PRKCD,PRKCE,PRKCZ,PRR5L,PSEN1,PSMB7,PSMD8,PSMD9,PTGER4,PTP4A3,PTPN22,PTPN23,PYCARD,PYDC1,RAB29,RAC2,RAPGEF3,RASGRP1,RBCK1,RBM22,RBP4,RBPMS,RFX6,RGCC,RHOU,RIPK2,RIPOR1,RNF31,RPH3AL,RPL28,RUFY3,RUVBL1,SAA1,SCAMP5,SEC16B,SELENOI,SELENOK,SEMA5A,SERP1,SFN,SFRP2,SH3GLB1,SIRT3,SLC30A8,SLC35D3,SLC51B,SMAD4,SMO,SNIP1,SORL1,SOX4,SPHK1,SPPL3,SRC,SREBF2,SRI,STARD7,STOM,STX4,STXBP5L,SULF2,SYBU,SYK,SYTL4,TARDBP,TCP1,TDRD12,TENM1,TFDP2,TGFB1,TGFB2,TGFBR1,TLR1,TLR2,TLR3,TLR4,TLR9,TM7SF3,TM9SF4,TMEM110,TMEM173,TMEM27,TMEM30B,TNF,TNFRSF14,TNFRSF4,TNFSF14,TOMM7,TP53,TP53BP2,TP63,TP73,TPR,TRIM28,TRIM6,TRIP6,TRPM4,TSG101,TSGA13,TTN,TWIST1,U2AF1,U2AF2,UBE2D3,UBE2J2,UBE2L3,UBL5,UBR5,UCN3,UGCG,UNC13B,USP36,VAMP2,VEGFC,VPS11,VPS28,VPS35,VSNL1,VTCN1,WBP11,WDR46,WDR75,WLS,WNT3A,WNT5A,WRAP53,XBP1,XPO4,YWHAB,YWHAE,YWHAG,YWHAH,YWHAZ,ZBED3,ZBTB17,ZC3H12A,ZDHHC8,ZIC1,ZPR1	TetrapodAncestor	95.9551
GO.Biological.Process	GO:0035966	response.to.topologically.incorrect.protein	358	8.624903e-101	1.114079e-96	3.111952e-99	1.385870e+0	ACADVL,ADD1,AMFR,ANKZF1,ASNA1,ASNS,ATF3,ATF4,ATF6,ATF6B,ATP6V0D1,ATXN3,BAG6,BAK1,BAX,BHLHA15,CALR,CCL2,CCND1,CHAC1,CLU,CREB3,CREB3L1,CREB3L2,CREB3L3,CREBRF,CTDSP2,CTH,CUL3,CUL7,CXCL8,CXXC1,DAB2IP,DAXX,DCTN1,DDX11,DERL1,DERL2,DERL3,DNAJA1,DNAJB1,DNAJB11,DNAJB12,DNAJB5,DNAJC4,DZIP3,EDEM1,EDEM2,EDEM3,EIF2AK2,EIF2AK3,EP300,ERN1,ERO1A,EXTL1,EXTL2,EXTL3,F12,FAF2,FBXO6,FGF21,FKBP14,GFPT1,GOSR2,GSK3A,HDGF,HERPUD1,HERPUD2,HSF1,HSP90AB1,HSP90B1,HSPA2,HSPA4,HSPA4L,HSPA5,HSPA8,HSPB1,HSPB2,HSPB3,HSPB7,HSPH1,HYOU1,IFNG,JKAMP,KDELR3,KLHDC3,KLHL15,LMNA,MANF,MBTPS1,MBTPS2,MFN2,MYDGF,OPTN,PACRG,PARP16,PDIA6,PLA2G4B,POMT1,POMT2,PPP1R15A,PPP2R5B,PREB,PRKN,PTPN1,RHBDD1,RNF121,RNF126,RNF175,RNF185,RNF5,SDF2L1,SEC61A1,SEC61A2,SEC61B,SEC61G,SEC62,SEC63,SERP1,SERP2,SERPINH1,SHC1,SRPRA,SRPRB,SSR1,STC2,STT3B,STUB1,SYVN1,TBL2,THBS1,THBS4,TLN1,TM7SF3,TMBIM6,TMEM129,TOR1A,TOR1B,TPP1,UBE2J2,UBE2W,UBXN4,UFD1,UGGT1,VAPB,VCP,WFS1,WIPI1,XBP1,YOD1,ZBTB17	TetrapodAncestor	95.9531
GO.Biological.Process	GO:1901990	regulation.of.mitotic.cell.cycle.phase.transition	359	1.068308e-100	1.379933e-96	3.843826e-99	1.222152e+0	ACTR1A,AIF1,ALMS1,ANAPC1,ANAPC11,ANAPC16,ANAPC2,ANAPC4,ANAPC5,ANKRD17,ANLN,ANXA1,APC,APEX1,APP,ATAD5,ATM,AURKA,AURKB,BAX,BCL2,BID,BRCA1,BRD4,BTG2,BTRC,BUB1,CARM1,CASP2,CCL2,CCNB1,CCNB3,CCND1,CCND2,CCP110,CDC14A,CDC14B,CDC16,CDC20,CDC23,CDC25C,CDC26,CDC27,CDC45,CDC6,CDC73,CDCA5,CDK1,CDK10,CDK2,CDK2AP2,CDK4,CDK5RAP2,CDK6,CDKN1A,CDKN1B,CDKN1C,CDKN2B,CENPE,CENPF,CENPJ,CEP164,CEP192,CEP250,CEP41,CEP57,CEP63,CEP72,CEP78,CHEK2,CHMP4C,CKAP5,CLASP1,CNOT1,CNOT10,CNOT11,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT8,CNTRL,CRADD,CSNK1D,CSNK1E,CTDSP1,CTDSP2,CTDSPL,CUL1,CUL3,CUL4A,CYP1A1,DACT1,DBF4B,DCTN1,DCTN3,DCUN1D3,DDB1,DDX3X,DLGAP5,DONSON,DUSP1,DYNC1H1,DYNC1LI1,DYNLL1,E2F1,E2F4,E2F7,E2F8,ECD,EGFR,EP300,ERCC2,ERCC3,ESPL1,EZH2,FANCI,FBXL7,FBXO31,FBXO5,FBXO7,FGF10,FGFR1OP,FOXN3,FOXO4,FZR1,GADD45A,GEN1,GIGYF2,GJC2,GML,GPNMB,GPR132,GTSE1,HAUS2,HAUS3,HAUS4,HAUS6,HAUS7,HAUS8,HECW2,HMGA2,HMMR,HSPA2,HUS1,HUS1B,ID2,IK,INO80,JADE1,KANK2,KCNA5,KCNH5,KLHL22,LCMT1,LSM11,MAD1L1,MAD2L1,MAD2L1BP,MAD2L2,MAPRE1,MDM2,MDM4,MECP2,MEPCE,MIIP,MRE11,MRNIP,MTA3,MTBP,MUC1,MUS81,MYO16,NAE1,NBN,NDC80,NEDD1,NEK11,NEK6,NEUROG1,NINL,NOP53,NPM1,NPM2,NSMCE2,ODF2,ORAOV1,PAFAH1B1,PBX1,PCBP4,PCID2,PCM1,PCNA,PCNT,PDPN,PHOX2B,PID1,PIDD1,PINX1,PKD1,PKD2,PKIA,PLAGL1,PLCB1,PLK1,PLK2,PLK3,PLK4,PLK5,PML,PPP1R9B,PRKACA,PRKAR2B,PRKDC,PRMT1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTEN,RAD17,RAD21,RAD51B,RAD51C,RB1,RCC2,RDX,RFWD3,RGCC,RINT1,RNASEH2B,RPA2,RPS27A,RPS27L,RPTOR,SFI1,SFN,SIRT2,SLFN11,SMARCA4,SOX4,SSNA1,TERT,TEX14,TFDP2,TGFB1,TICRR,TMOD3,TNKS1BP1,TOPBP1,TP53,TP63,TP73,TPR,TPRA1,TPX2,TRIAP1,TRIP13,TTK,TUBA1A,TUBB,TUBB4A,TUBB4B,UBC,UBE2C,UBE2D1,UBE2E1,UBE2E2,USP47,VPS4A,VPS4B,WNT10B,XPC,YWHAE,YWHAG,ZFP36L1,ZFP36L2,ZFYVE19,ZNF207,ZNF385A,ZNF830,ZW10	TetrapodAncestor	95.8601
GO.Biological.Process	GO:0042542	response.to.hydrogen.peroxide	360	1.772698e-100	2.289794e-96	6.360539e-99	1.413942e+0	ABL1,ADA,ADAM9,AIFM1,AKR1B1,ANKZF1,ANXA1,APEX1,APTX,AQP1,AREG,ARG1,AXL,BAD,BAK1,BCL2,BECN1,BNIP3,CASP3,CAT,CBX8,CDK1,COL1A1,CRK,CRYAB,CYP1B1,DUSP1,ECT2,EEF2,ETS1,EZH2,FABP1,FKBP1B,FOSL1,FOXO1,FXN,GLRX2,GNAO1,HBA1,HBA2,HBB,HDAC2,HMOX1,HP,HSF1,IL18BP,IL18RAP,IL6,JUN,KCNA5,KDM6B,KLF2,KLF4,KPNA4,LCN2,LDHA,MAP1LC3A,MAP3K5,MB,MDM2,MYB,NET1,NR4A3,PARK7,PAX2,PCGF2,PCNA,PDCD10,PDGFD,PDGFRB,PLEKHA1,PPIF,PPP1R15B,PPP2CB,PPP5C,PRDX3,PRKAA1,PRKCD,PTK2B,RELA,RPS3,SETX,SIRT1,SLC8A1,SOD1,SRC,STAR,STAT6,STK24,STK26,TNFAIP3,TRPA1,TRPC6,TRPM2,TXNIP,UBE3A,ZNF277,ZNF580	TetrapodAncestor	95.6402
GO.Biological.Process	GO:0098773	skin.epidermis.development	361	1.874841e-100	2.421732e-96	6.708399e-99	1.389617e+0	ACVR1B,ALX4,APCDD1,BCL2,CD109,CDC42,CELSR1,CTNNB1,DKK1,DLL1,DNASE1L2,DSG4,EDA,EDAR,EGFR,ERCC2,FGF10,FGF7,FGFR2,FOXE1,FOXN1,FOXQ1,FUZ,FZD3,FZD6,GNAS,GORAB,HDAC1,HDAC2,HOXC13,IGFBP5,INHBA,INTU,KDF1,KRT17,KRT25,KRT27,KRT71,KRT84,LAMA5,LDB2,LGR4,LGR5,LHX2,LRP4,NF1,NOTCH1,NSDHL,NSUN2,PDGFA,RBPJ,RELA,SMO,SNAI1,SOS1,SOSTDC1,SOX18,SOX9,SPINK5,TGFB2,TGM3,TMEM79,TNFRSF19,TP63,TRPC4AP,VANGL2,WNT10A,ZDHHC21	TetrapodAncestor	95.6159
GO.Biological.Process	GO:0070555	response.to.interleukin-1	362	2.165504e-100	2.797182e-96	7.727021e-99	1.380584e+0	ABCC2,ADAMTS12,ADAMTS7,AES,ANKRD1,ANXA1,CACTIN,CCL1,CCL11,CCL13,CCL14,CCL15,CCL15-CCL14,CCL16,CCL17,CCL18,CCL19,CCL2,CCL21,CCL22,CCL23,CCL3,CCL3L3,CCL4,CCL4L2,CCL5,CCL7,CCL8,CD38,CD40,CEBPB,CHI3L1,CITED1,CX3CL1,CXCL8,CYBA,DAB2IP,EDN1,EGR1,EPO,ETS1,FGG,HAS2,HDAC4,HIF1A,HNMT,IGBP1,IKBKB,IL17A,IL1A,IL1R1,IL1RL2,IL6,IRAK1,IRAK3,IRAK4,KLF2,LCN2,LGALS9,MAPK3,MTHFR,MYLK3,NFKB1,NKX3-1,NLRP7,OTUB1,PCK1,PLCB1,PRKCA,PRKCI,PTGIS,PYCARD,RC3H1,RELA,RIPK2,RPS6KA4,RPS6KA5,SELE,SFRP1,SLC30A8,SNCA,SOX9,SRC,ST18,TAF9,TFPI,TNFRSF11A,TNIP2,TRAF6,TRIM63,UPF1,USP10,XCL1,XCL2,YTHDC2,YY1,ZC3H12A	TetrapodAncestor	95.5533
GO.Biological.Process	GO:0001959	regulation.of.cytokine-mediated.signaling.pathway	363	3.129128e-100	4.041895e-96	1.113470e-98	1.339182e+0	ADAR,ADIPOQ,AGPAT1,AGPAT2,ANGPT1,APOA1,ARG1,AXL,BIRC2,BIRC3,CACTIN,CARD16,CASP1,CASP4,CASP8,CAV1,CBFB,CCDC3,CCL5,CD24,CD300LF,CD74,CHUK,CLIP3,CREBRF,CSF1,DCST1,EDN1,ELF1,F2RL1,FADD,GAS6,GSTP1,HIF1A,HIPK1,HSP90AB1,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNAR1,IFNAR2,IFNB1,IFNG,IFNGR1,IFNGR2,IKBKB,IKBKG,IL1R1,IL1R2,IL1RN,IL36RN,IL6,IRAK1,IRAK3,IRF3,IRF7,IRGM,JAK2,LIFR,MADD,MMP12,MUL1,NLRC5,NOL3,NR1H2,NR1H3,NR1H4,OTULIN,PADI2,PAFAH1B1,PALM3,PARP14,PARP9,PELI3,PIAS1,PIAS4,PPARG,PRKN,PTPN1,PTPN11,PXDN,PYCARD,PYDC1,PYDC2,RBCK1,RFFL,RIPK1,RIPK2,RNASEL,RNF31,ROBO1,RPS27A,RUNX1,SCRIB,SHARPIN,SIGIRR,SLIT2,SLIT3,SOCS1,SOCS3,SPHK1,SPPL2A,SPPL2B,STAP1,STAT1,STAT2,SUMO1,SYK,TAX1BP1,TICAM2,TNF,TNFAIP3,TNFRSF1A,TRADD,TRAF1,TRAF2,TRAIP,TREM2,TRIM32,TRIM44,TRIM6,TXK,UBC,USP18,VRK2,WNT5A,ZNF675	TetrapodAncestor	95.3934
GO.Biological.Process	GO:0019752	carboxylic.acid.metabolic.process	364	3.622749e-100	4.679505e-96	1.285578e-98	1.149772e+0	AACS,AADAT,AARS,AARS2,AARSD1,AASDHPPT,AASS,ABAT,ABCC2,ABCD1,ABCD2,ABCD3,ABHD10,ABHD14A-ACY1,ABHD5,ACAA2,ACACA,ACACB,ACAD10,ACAD8,ACAD9,ACADL,ACADM,ACADS,ACADVL,ACAT1,ACAT2,ACBD5,ACMSD,ACO1,ACOT1,ACOT11,ACOT12,ACOT2,ACOT4,ACOT6,ACOT7,ACOT8,ACOX2,ACOX3,ACOXL,ACSBG1,ACSBG2,ACSF2,ACSL1,ACSL3,ACSL4,ACSL5,ACSM1,ACSM2A,ACSM2B,ACSM3,ACSM4,ACSM5,ACSM6,ACSS1,ACSS2,ACY1,ADH7,ADI1,ADIPOQ,ADIPOR1,ADIPOR2,ADO,ADPGK,ADSS,ADSSL1,AFMID,AGMAT,AGXT,AGXT2,AHCY,AHCYL1,AHCYL2,AKR1A1,AKR1D1,ALDH1A3,ALDH1L1,ALDH1L2,ALDH3A2,ALDH4A1,ALDH5A1,ALDH6A1,ALDH7A1,ALDH8A1,ALDOA,ALDOB,ALKBH7,ALOX15,ALOX15B,ALOX5,ALOX5AP,AMACR,AMDHD2,APIP,ARG1,ARG2,ART4,ARV1,ASL,ASNS,ASNSD1,ASPA,ASPG,ASS1,ATF4,ATIC,ATP8B1,AUH,AWAT1,AZIN1,AZIN2,BAAT,BCAN,BCAT1,BCAT2,BCKDHA,BCKDHB,BCKDK,BCO2,BDH2,BGN,BLMH,BPGM,BPHL,BRCA1,BSG,BTD,C14orf159,C3,CARNMT1,CARNS1,CARS,CBR1,CBR4,CBS,CCDC12,CD74,CDO1,CEL,CES1,CES2,CH25H,CHST12,CHST14,CKMT1A,CKMT1B,CKMT2,CLN3,CMAS,CPS1,CPT1A,CPT1B,CPT1C,CPT2,CRABP1,CRABP2,CRAT,CROT,CRTAP,CRYM,CS,CSAD,CSGALNACT1,CSPG4,CTH,CTNS,CTPS1,CTPS2,CYB5A,CYB5R3,CYGB,CYP1A1,CYP1A2,CYP1B1,CYP26A1,CYP26B1,CYP26C1,CYP27A1,CYP27C1,CYP2A13,CYP2A6,CYP2A7,CYP2B6,CYP2C18,CYP2C19,CYP2C8,CYP2C9,CYP2D6,CYP2F1,CYP2J2,CYP2S1,CYP2W1,CYP39A1,CYP46A1,CYP4A11,CYP4F22,CYP4F8,CYP4V2,CYP7A1,CYP8B1,D2HGDH,DAGLA,DAGLB,DARS,DARS2,DBT,DCN,DCT,DCXR,DDAH1,DDC,DDO,DECR1,DEGS1,DHFR,DHFR2,DHTKD1,DLAT,DLD,DPEP1,DPYD,DSE,DSEL,EARS2,ECH1,ECHDC1,ECHDC2,ECHS1,ECI1,ECI2,EDN1,EDN2,EGLN1,EGLN2,EGLN3,EHHADH,ELOVL1,ELOVL2,ELOVL3,ELOVL4,ELOVL6,ELOVL7,ENO3,ENO4,ENOSF1,ENSG00000249319,ENSG00000255730,ENSG00000255835,ENSG00000256591,ENSG00000260300,ENSG00000260643,ENSG00000269547,ENSG00000276490,ENSG00000284512,EPHX2,EPRS,ERO1A,ERO1B,ETFA,ETFB,FA2H,FAAH,FABP3,FADS1,FADS2,FADS3,FADS6,FAH,FAM213B,FARS2,FARSA,FASN,FDXACB1,FH,FN3K,FOLH1,FPGS,FTCD,GADL1,GAPDH,GAPDHS,GARS,GART,GATB,GATC,GBA2,GCAT,GCDH,GCH1,GCK,GCLM,GCSH,GFPT1,GFPT2,GGH,GGT1,GGT2,GGT5,GGT7,GGTLC2,GGTLC3,GHR,GLDC,GLO1,GLUD1,GLUD2,GLUL,GLYAT,GLYATL1,GLYATL2,GMPS,GNE,GNMT,GOT1,GOT1L1,GOT2,GPAM,GPAT4,GPT,GPT2,GRHPR,GSS,GSTA1,GSTM2,GSTO2,GSTP1,GSTZ1,HAAO,HACD1,HACD2,HACD3,HACD4,HACL1,HADHA,HADHB,HAO1,HAO2,HARS,HARS2,HDC,HGD,HIBCH,HIF1A,HK3,HLCS,HMGCL,HNF4A,HNMT,HOGA1,HPD,HPGD,HPGDS,HSD17B12,HSD17B4,HSD17B8,HSD3B7,HTD2,HYKK,IARS,IARS2,IDH2,IDH3A,IDH3G,IDNK,IDO1,IDO2,IDUA,IGF1,IL4I1,IVD,IYD,KARS,KMO,KYAT1,KYNU,LARS,LARS2,LDHA,LDHAL6A,LDHAL6B,LDHB,LDHC,LEP,LGSN,LIPE,LIPF,LPIN1,LPIN3,LPL,LRAT,LTC4S,LYPLA1,LYPLA2,MAPK14,MAPK3,MAPKAPK2,MARS2,MCAT,MCCC1,MCCC2,MCEE,MDH1B,MDH2,ME1,ME2,ME3,MECP2,MECR,MGLL,MGST2,MGST3,MIF,MLYCD,MORC2,MPC1,MPC2,MPST,MRI1,MRS2,MSRA,MTAP,MTHFD1,MTHFD1L,MTHFD2,MTHFD2L,MTHFR,MTHFS,MTRR,MUT,NAALAD2,NAGK,NAGS,NARS,NARS2,NAT8L,NDUFAB1,NFS1,NIT2,NMNAT3,NNT,NOS1,NOS2,NOS3,NOX4,NPC1,NPL,NR1H4,NR4A3,NR5A2,NUDT19,NUDT7,ODC1,OGDH,OGDHL,OLAH,OSBP,OSBPL2,OSBPL3,OSBPL9,OTC,OXSM,P4HA1,P4HB,PADI1,PADI2,PADI3,PADI4,PADI6,PAH,PAM,PANK2,PARK7,PARP9,PARS2,PC,PCBD1,PCCB,PCK1,PCK2,PCYOX1,PCYOX1L,PDHA1,PDHA2,PDHB,PDHX,PDPN,PDXDC1,PDZD11,PECR,PEMT,PEPD,PER2,PEX13,PEX2,PEX7,PFKFB1,PFKFB2,PFKL,PFKP,PGAM1,PGAM2,PGAM4,PGD,PGK1,PGK2,PGM2L1,PHGDH,PHYH,PHYKPL,PKLR,PKM,PLA2G10,PLA2G15,PLA2G1B,PLA2G3,PLA2G4A,PLA2G4B,PLA2G4F,PLA2G5,PLOD2,PLP1,PM20D1,PNKD,PNPLA3,POLG2,POR,PPARA,PPARD,PPARG,PPARGC1A,PRDX4,PRG3,PRKAA1,PRKAA2,PRKAB1,PRKAG2,PRKAG3,PRKAR2B,PRODH,PRODH2,PSAT1,PSPH,PTGDS,PTGES,PTGES2,PTGES3L-AARSD1,PTGIS,PTGR1,PTGR2,PTGS1,PTS,PYCR1,PYCR2,PYCR3,QDPR,QKI,QRSL1,RARS,RARS2,RBP1,RDH10,RENBP,RGN,RIMKLA,RIMKLB,SARDH,SARS,SARS2,SCD,SCLY,SCP2,SCPEP1,SDHA,SDHAF2,SDHAF3,SDHB,SDHD,SDHD,SDS,SDSL,SEPHS1,SEPSECS,SERINC3,SERINC5,SESN2,SGPL1,SHMT1,SHMT2,SIRT4,SLC16A1,SLC16A8,SLC19A1,SLC1A3,SLC23A1,SLC23A2,SLC25A17,SLC25A21,SLC27A1,SLC27A2,SLC27A3,SLC27A4,SLC27A5,SLC27A6,SLC2A1,SLC2A3,SLC34A1,SLC35D1,SLC46A1,SLC5A6,SLC6A14,SLC6A6,SLC6A8,SLC7A4,SLC7A5,SLC7A6,SLC7A7,SLC7A8,SMS,SNCA,SORD,SRD5A2,SRR,SSTR4,ST20-MTHFS,ST3GAL1,ST6GAL1,STAR,SUCLA2,SUCLG2,SULT2A1,SYK,TARS,TAT,TBXAS1,TDO2,TECR,TECRL,TH,THEM4,THEM5,THNSL2,TLR2,TNFRSF1A,TPH1,TPH2,TYMS,TYR,TYRP1,UCP3,UEVLD,UGT1A1,UGT1A10,UGT1A3,UGT1A4,UGT1A5,UGT1A6,UGT1A8,UGT1A9,UPB1,UROC1,UST,VCAN,VNN1,VNN2,VNN3,WARS,WARS2,XBP1,YARS,YARS2	TetrapodAncestor	95.3298
GO.Biological.Process	GO:0051090	regulation.of.sequence-specific.DNA.binding.transcription.factor.activity	365	7.011538e-100	9.056804e-96	2.481316e-98	1.191130e+0	ABRA,ADAM8,ADGRF1,ADGRG3,ADORA3,AGER,AGT,ALK,AMH,ANXA3,ANXA4,APP,AR,ARHGEF2,ARID5B,ARRB1,ARRB2,BCL10,BHLHE40,BMP7,BTK,BTRC,BUD31,C3orf33,CACTIN,CAMK1D,CAMK2A,CARD11,CARD14,CARD16,CARM1,CAT,CD36,CD40,CDKN2A,CEBPG,CFLAR,CHP1,CHUK,CIB1,CLU,CMKLR1,COMMD1,COMMD7,CREBZF,CRTC3,CTH,CTNNB1,CYP1B1,CYTL1,DAB2IP,DAP,DDR2,DDRGK1,DDX58,DHX9,EDA,EDA2R,EDN1,EGLN1,EIF2AK2,EIF2AK4,EP300,EPHA5,ERC1,ESR1,ESR2,EZH2,FANCA,FER,FLNA,FOS,FOSL1,FOXA1,FOXA2,FOXH1,FOXJ1,FOXP3,FOXS1,FZD1,FZD2,FZD4,FZD6,GAS6,GREM1,GTF2A2,HAND1,HAND2,HAVCR2,HCK,HDAC2,HDAC4,HDAC5,HEYL,HIPK2,HMOX1,ID1,ID2,ID3,IKBKB,IKBKG,IL10,IL1B,IL1RAP,IL4,IL5,IL6,INS,IRAK1,IRAK3,IRAK4,ITCH,ITGB2,JAK2,JMY,JUN,JUP,KDM1A,KDM5A,KEAP1,KLF4,KRAS,LGALS9,LRP5,LRP6,LRP8,LRRC14,LRRFIP1,MAD2L2,MALT1,MAP3K10,MAP3K13,MAP3K7,MAPK1,MAPK10,MAPK11,MAPK14,MAPK3,MAPK8,MAPK9,MBTPS2,MED13,MEN1,MID2,MSX2,MTDH,MTPN,MYOCD,NDP,NEUROD1,NEUROG1,NEUROG2,NEUROG3,NFAM1,NFKB1,NFKB2,NFKBIB,NFKBID,NHLH2,NKX6-1,NLRC3,NLRC4,NLRC5,NLRP2,NOD1,NPM1,NR0B1,NR0B2,NR1H4,NTRK1,OPRD1,OTULIN,PARK7,PARP10,PELI1,PEX14,PIAS4,PIDD1,PIM1,PINK1,PKHD1,PLA2G10,PLA2G1B,PLPP3,POU4F1,PPARG,PPARGC1A,PPARGC1B,PPP2R5B,PPP3CA,PRDX3,PRKCB,PRKCH,PRKCI,PRKCQ,PRKCZ,PRKD1,PRKD2,PROX1,PSMD10,PTCH1,PTEN,PTGIS,PYCARD,PYDC1,PYDC2,RAB7B,RB1,RBCK1,RELA,RELN,RGCC,RIPK1,RIPK2,RIPK3,RIPK4,RLIM,RNF2,RNF25,RNF31,RNF41,RPS27A,RPS3,RPS6KA4,RPS6KA5,RWDD1,RWDD3,S100A12,S100A8,S100A9,SETD6,SFRP4,SFRP5,SGK1,SIGIRR,SIK1,SIRT1,SMAD7,SMARCA4,SMARCB1,SMO,SP100,SPHK1,SPOP,SRF,STK36,SUFU,SUMO1,SYK,TAB1,TAB2,TAB3,TAF1,TAF12,TAF6,TAF6L,TAX1BP1,TCF3,TERF2IP,TGFB1,TICAM1,TIRAP,TLR2,TLR3,TLR4,TLR6,TLR9,TMEM189-UBE2V1,TMIGD3,TNF,TNFAIP3,TNFRSF11A,TNFRSF4,TNFSF11,TNFSF18,TRADD,TRAF1,TRAF2,TRAF3,TRAF5,TRAF6,TRAPPC9,TRIB1,TRIM13,TRIM21,TRIM22,TRIM25,TRIM32,TRIM34,TRIM37,TRIM38,TRIM5,TRIM62,TRIM8,TWIST1,UBC,UBE2I,UBE2N,UFL1,USP7,VEGFA,WFS1,WNT1,WNT10B,WNT3A,WNT5A,WWP2,XCL1,ZC3H12A,ZNF431,ZNF675	TetrapodAncestor	95.043
GO.Biological.Process	GO:0050708	regulation.of.protein.secretion	366	7.276654e-100	9.399254e-96	2.568102e-98	1.183363e+0	AACS,ABAT,ABCC8,ABL1,ACHE,ADAM8,ADAM9,ADCY5,ADORA2A,ADRA2A,ADRA2C,AGTR2,ALOX15B,ANGPT1,ANKRD1,ANO1,ANXA1,ANXA4,APOA1,APOA2,ARF1,ARFIP1,ARG2,ARL2,ARL2BP,ARNTL,ARRB1,ATG5,ATP13A2,BAD,BANK1,BLK,BMP6,BMP8A,BRSK2,C1QTNF12,C1QTNF3,C2CD2L,C5,CACNA1A,CACNA1C,CACNA1D,CACNA1E,CACNA2D2,CADM1,CAPN10,CARD16,CARD17,CARD18,CARTPT,CASP1,CASP5,CASR,CCL19,CCL3,CCL5,CCR7,CD14,CD2,CD274,CD34,CD38,CD40,CD58,CDK16,CFTR,CHIA,CHUK,CIDEA,CLEC4E,CLEC6A,CLEC9A,CNR1,CPT1A,CRTAM,CSF1R,DDX58,DHX9,DISP1,DNAJC1,DNM1L,DOC2B,DPH3,DRD2,DRD3,DRD4,EFNA5,EGFR,ENSG00000173366,EPHA5,ERP29,EXPH5,EZR,F2R,F2RL1,FAM3D,FCN1,FERMT1,FFAR1,FFAR2,FFAR4,FGG,FGR,FKBP1B,FN1,FOXA2,FOXP3,GAPDH,GAS6,GATA3,GCK,GHSR,GIP,GIPR,GJA1,GLP1R,GLUD1,GLUL,GOLPH3,GPAM,GPER1,GPLD1,GPR68,GSDMD,HAVCR2,HIF1A,HMGB1,HMGCR,HMGN3,HMHB1,HNF4A,HTR2B,ICA1,IDH2,IFNA2,IFNAR1,IFNG,IGF1,IL10,IL13,IL17A,IL17F,IL17RA,IL17RB,IL17RC,IL1A,IL1B,IL1R2,IL1RAP,IL1RL1,IL2,IL26,IL33,IL36RN,IL5,IL6,INHBB,INS,IRF3,IRS1,IRS2,ISL1,ITPR1,ITPR2,ITPR3,JAGN1,JAK2,KARS,KCNA5,KCNB1,KCNC2,KCNG2,KCNJ11,KCNS3,KIF5B,KRT20,LEP,LGALS9,LGR4,LLGL2,LPL,LRP5,LRRC32,LYN,MAP4K4,MAPK11,MAPK14,MAPK3,MARCKS,MCU,MIF,MMP12,MPC2,MTNR1B,MYO18A,MYRIP,NDUFAF2,NEUROD1,NKX6-1,NLRP1,NLRP10,NLRP2,NLRP7,NNAT,NOS2,NOV,NPFF,NR0B2,NR1D1,NR1H2,NR1H3,NR1H4,NRXN1,OPRM1,OR51E2,ORM1,ORM2,OXCT1,P2RX7,P3H1,PAEP,PAM,PANX1,PCK2,PDE8B,PER2,PFKFB2,PFKL,PHPT1,PIK3C3,PIM3,PLA2G1B,PLA2G6,PML,PPARD,PPP3CA,PPP3CB,PRKCA,PRKCE,PRKCZ,PRKN,PSMD9,PTGER4,PTPN11,PTPN22,PTPN23,PYCARD,PYDC1,PYDC2,RAB11FIP1,RAB11FIP5,RAP1A,RAPGEF3,RASGRP1,RBP4,REST,RFX3,RFX6,RGCC,RHBDD3,RHBDF1,RHBDF2,RIPK2,RPH3AL,RSAD2,SAA1,SCAMP5,SELENOK,SERGEF,SERP1,SFRP1,SIDT2,SIRT3,SIRT4,SLC16A1,SLC25A5,SLC25A6,SLC2A1,SLC2A2,SLC30A8,SLC8B1,SLC9B2,SNAP25,SOCS1,SOX4,SRC,SRCIN1,SREBF1,SRI,SSC5D,SSTR5,STX1A,STX4,STXBP4,STXBP5,STXBP5L,SYBU,SYK,SYT11,SYT4,SYT7,SYT9,SYTL4,TARDBP,TFAP2B,TGFB1,TGFB2,TIAM1,TLR1,TLR10,TLR2,TLR4,TLR5,TLR6,TLR9,TM7SF3,TMBIM6,TMEM27,TNF,TNFRSF14,TNFRSF21,TNFRSF4,TNFRSF9,TRAF2,TRAF6,TRIM6,TRPM4,TTN,TWIST1,UCN3,UCP2,UNC13B,UQCC2,UTS2,VEGFC,VPS35,VSNL1,VTCN1,WLS,WNT5A,XBP1,ZC3H12A	TetrapodAncestor	95.0269
GO.Biological.Process	GO:0032729	positive.regulation.of.interferon-gamma.production	367	7.367452e-100	9.516538e-96	2.593062e-98	1.500891e+0	ABL1,BCL3,CCR2,CD14,CD2,CD226,CD276,CD3E,CEBPG,EBI3,FADD,FAM49B,FZD5,HAVCR2,HMHB1,HRAS,IFNAR1,IFNL1,IL12A,IL12B,IL12RB1,IL12RB2,IL18,IL18R1,IL1B,IL2,IL21,IL23A,IL23R,IL27,IL27RA,IRF8,ISL1,KLRK1,LGALS9,PDE4B,PDE4D,PTPN22,PYCARD,RASGRP1,RIPK2,SASH3,SLAMF6,SLC11A1,TLR3,TLR4,TLR9,TNF,TNFRSF13C,TXK,WNT5A,ZFPM1,ZP3	TetrapodAncestor	95.0215
GO.Biological.Process	GO:0003197	endocardial.cushion.development	368	8.038359e-100	1.038315e-95	2.821508e-98	1.461328e+0	ACVRL1,BMP2,BMP4,BMP5,BMP7,BMPR1A,BMPR2,CRELD1,DCHS1,ENG,ERG,FOXF1,GATA4,HEY1,HEYL,ISL1,JAG1,MDM2,MSX1,MSX2,NOG,NOTCH1,RBPJ,SMAD4,SNAI1,SNAI2,SOX9,TBX2,TBX20,TBX5,TGFB2,TGFBR2,TMEM100,TWIST1	TetrapodAncestor	94.9837
GO.Biological.Process	GO:0044087	regulation.of.cellular.component.biogenesis	369	8.387879e-100	1.083462e-95	2.936212e-98	1.117522e+0	ABCA1,ABI2,ABL1,ACE,ACE2,ACTR2,ACTR3,ACTR3B,ACTR3C,ACVRL1,ADAMTS16,ADD1,ADGRB1,ADGRB2,ADGRB3,ADGRL1,ADGRL3,ADNP,AGRN,AGT,AJUBA,AKAP13,ALMS1,ALOX15,AMIGO2,AMIGO3,ANKRD27,ANKRD53,ANLN,ANTXR1,AP1AR,APC,APOA1,APOD,APOE,AQP1,ARAP1,ARF1,ARF6,ARFIP1,ARHGAP18,ARHGAP28,ARHGAP35,ARHGAP6,ARHGEF2,ARL2,ARPC1A,ARPC1B,ARPC2,ARPC4,ARPC4-TTLL3,ARPC5,ARPIN,ASAP1,ASAP3,ASIC2,ATAT1,ATF7IP,ATG3,ATG5,ATM,ATMIN,ATP13A2,ATP8B1,ATR,ATXN2,ATXN2L,AUTS2,AVIL,BAG4,BAIAP2L2,BAX,BBS4,BCAS3,BCL2L11,BCLAF1,BDNF,BECN1,BID,BIK,BIN3,BIRC2,BMP10,BMP7,BRAF,BRCA1,BUD23,C15orf38-AP3S2,C15orf62,C9orf72,CAMSAP1,CAMSAP3,CAND1,CAPG,CAPZA2,CAPZA3,CAPZB,CARMIL1,CARMIL2,CAV1,CAV3,CBFB,CBLN1,CBLN2,CCDC151,CCDC88A,CCK,CCL11,CCL19,CCL21,CCP110,CCR7,CD36,CDC34,CDC42,CDC42EP1,CDC42EP2,CDC42EP3,CDC42EP4,CDC42EP5,CDK5RAP2,CDKN1B,CENPJ,CEP120,CEP295,CEP97,CHD1L,CHGA,CHMP1A,CHMP1B,CHMP2A,CHMP2B,CHMP4A,CHMP4B,CHMP4C,CHMP5,CHRNB2,CLASP1,CLASP2,CLDN1,CLDN5,CLIP3,CLRN1,CLSTN2,CLU,CNOT1,CNOT2,CNOT6,CNOT6L,COBL,COL16A1,COLQ,CORO1A,CORO1B,CRBN,CREB1,CROCC,CRYAB,CSF3,CTGF,CTNNB1,CTTN,CUL4A,CUX2,CXCL13,CYFIP1,CYR61,DAB2IP,DACT1,DAPK3,DCDC2,DCTN1,DDB1,DDB2,DDX3X,DEF8,DIMT1,DKK1,DLC1,DLG1,DLG5,DMTN,DNAJA4,DNAJB1,DNAJB6,DNAJB8,DNAJC15,DNM1L,DNM2,DOCK11,DPYSL3,DYNC2LI1,DYNLL1,EDN1,EEF2K,EFNA5,EIF2AK2,EIF4EBP1,EML2,ENSG00000284292,EPB41L5,EPHA1,EPHA2,EPHA3,EPHA7,EPHB1,EPHB2,EPHB3,EPS8,EPS8L1,EPS8L2,ERCC1,ERCC2,ERCC3,ERCC4,ERCC5,ESPN,ESR1,EVI5L,EVL,EZR,F2RL1,FAF1,FAM98A,FAS,FCHSD1,FCHSD2,FER,FES,FEZ1,FEZ2,FHOD1,FHOD3,FKBP4,FLOT1,FLRT1,FLRT2,FLRT3,FMN1,FMR1,FNBP1L,FOSL1,FRMD7,FSCN1,FUZ,FZD5,GAP43,GBA,GFAP,GHSR,GJA1,GMFB,GMFG,GPBAR1,GPM6A,GPM6B,GPR65,GRB2,GREM1,GRID2,GRIN1,GSN,GTF2F2,GTF2H1,GTF2H2,GTF2H3,GTF2H4,GTF2H5,H3F3A,HAP1,HAS2,HAS3,HAX1,HCFC1,HCK,HCLS1,HDAC4,HEATR1,HEY2,HGS,HIP1R,HJURP,HMGB1,HNF1A,HNF1B,HNRNPU,HRAS,HRG,HRK,HSF1,HSPA2,HSPA8,HTT,IAPP,ICE1,ID1,IDE,IFNG,IFT140,IFT20,IKBKB,IL1RAP,IL1RAPL1,IL5,INPP5J,INPP5K,INS,INSM1,IQGAP1,IRF8,IRGM,JCHAIN,JMY,JUN,KANK1,KCTD17,KIAA1324,KIF9,KIRREL1,KLF5,LATS1,LCAT,LCMT1,LCP1,LDB2,LDLRAD4,LIMK1,LINGO2,LMO4,LMOD1,LMOD3,LPAR1,LRRC24,LRRK2,LRRN1,LRRN3,LRRTM1,LRRTM2,LRRTM3,LRSAM1,LRTM1,LRTM2,MACF1,MALSU1,MAP4,MAPK9,MAPRE1,MAPT,MDM1,MECP2,MED25,MEF2C,MEFV,MET,MIEF2,MIEN1,MITF,MKKS,MLST8,MMP1,MMP14,MMP3,MORC1,MSN,MTM1,MTMR3,MTOR,MTPN,MUSK,MVB12A,MYADM,MYLK3,MYO10,MYO1C,NAPA,NAV3,NCK1,NCK2,NCKAP1,NCKAP1L,NCLN,NDEL1,NECTIN1,NEURL1,NF2,NKX2-5,NLGN1,NLGN3,NLRC3,NOP53,NOTCH1,NOTO,NOX4,NPHP1,NPHP4,NPHS1,NPM1,NPRL2,NPRL3,NR1H2,NRP1,NRXN1,NSMAF,NTRK1,NTRK2,NTRK3,NUDT16,NUP62,OCLN,OPRD1,ORMDL1,ORMDL2,ORMDL3,OXT,OXTR,P2RX7,PAK1,PAK3,PALM,PAN3,PARK7,PARP1,PARP10,PAXIP1,PDCD6IP,PDLIM5,PEX14,PEX5,PFN1,PFN2,PFN3,PFN4,PHLDB1,PHLDB2,PICK1,PIEZO1,PIH1D1,PIK3R1,PIKFYVE,PINK1,PIP4K2A,PIP4K2B,PIP4K2C,PKP2,PLA2G6,PLD1,PLEK,PLEKHG2,PLEKHM1,PLK1,PLK2,PLK4,PLPPR5,PMAIP1,PMEPA1,PODXL,PPFIA1,PPM1E,PPM1F,PPP1R16B,PPP2R5B,PREB,PREX1,PRKAA1,PRKACA,PRKCA,PRKCD,PRKCE,PRKCH,PRKCZ,PRKN,PROX1,PRUNE1,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PTEN,PTGER4,PTK2,PTK2B,PTPN11,PTPRD,PTPRJ,PXN,PYCARD,PYDC2,RAB17,RAB33A,RAB33B,RAB3GAP1,RAB3GAP2,RAB5A,RAB7A,RAC1,RAC2,RAF1,RALA,RALB,RAP1A,RAP1B,RAP1GAP,RAPGEF1,RAPGEF2,RAPGEF3,RASA1,RB1,RBM14,RCC2,RDX,REST,RGCC,RGS2,RHOC,RHOD,RHOG,RHOQ,RICTOR,RIOK1,RIOK2,RIOK3,RIPOR2,RNF4,RNF5,ROBO2,ROCK2,RP1,RPA2,RPA3,RPL13A,RPS3,RRN3,RUNX1,S100A10,S1PR1,SACS,SAXO1,SCFD1,SCIN,SDC4,SDCBP,SEC22B,SEC24B,SELP,SEPT7,SEPT9,SETX,SFRP1,SH3GLB1,SHANK1,SIRT2,SIRT6,SLAIN2,SLC39A12,SLC9A1,SLF1,SLF2,SLIT1,SLIT2,SLITRK1,SLITRK2,SLITRK3,SLITRK4,SLITRK5,SLITRK6,SMAD4,SMC1A,SMCR8,SMPD2,SMPD3,SNAI1,SNAI2,SNCA,SNCAIP,SNF8,SNX9,SORBS3,SORL1,SOST,SOX9,SPIDR,SPIRE1,SPIRE2,SPTB,SPTBN2,SPTBN5,SPTY2D1,SRC,SRF,SRGAP2C,SRPX2,SSH2,SSH3,STAG1,STAG2,STAM,STAP1,STIL,STMN1,STMN2,STUB1,STX18,STX1A,STX1B,STXBP1,STXBP6,SUB1,SUMO1,SVIP,SYNE2,SYNPO,SYT11,TAC1,TACSTD2,TAF1,TAL1,TAPT1,TBC1D14,TBC1D30,TBC1D7,TBCD,TBX20,TCL1A,TCTEX1D2,TEK,TENM1,TENM2,TERF1,TFIP11,TGFB1,TGFBR1,THBS1,THBS2,THRA,THY1,TJP1,TLR2,TLR4,TLR6,TMC8,TMEFF2,TMEM27,TMOD1,TMOD2,TMOD3,TMOD4,TMSB4Y,TNF,TNFRSF1A,TOGARAM1,TP53,TPBG,TPPP,TPR,TRABD2A,TRABD2B,TRAF3IP1,TRAPPC12,TRIM37,TRIM9,TRIOBP,TRMT112,TRPM2,TSG101,TUBB4A,TWF1,TWF2,TWIST1,UBE2V2,UNC13B,VASP,VCP,VDAC3,VEGFA,VIL1,VILL,VPS11,VPS16,VPS18,VPS35,VPS37B,VPS41,VPS4A,VPS4B,WARS,WASF2,WASHC2C,WDR43,WDR75,WNT1,WNT10B,WNT11,WNT4,WNT5A,WNT7A,XAF1,XPA,ZMYND8	TetrapodAncestor	94.9652
GO.Biological.Process	GO:0022405	hair.cycle.process	370	1.089115e-99	1.406810e-95	3.802189e-98	1.383868e+0	ACVR1B,ALX4,APCDD1,BCL2,CD109,CDC42,CDH3,CELSR1,CTNNB1,DKK1,DNASE1L2,DSG4,EDA,EDAR,EGFR,ERCC2,FGF10,FGF7,FGFR2,FOXE1,FOXN1,FOXQ1,FUZ,FZD3,FZD6,GNAS,GORAB,HDAC1,HDAC2,HOXC13,IGFBP5,INHBA,INTU,KRT17,KRT25,KRT27,KRT71,KRT84,LAMA5,LDB2,LGR4,LGR5,LHX2,LRIG1,LRP4,NF1,NOTCH1,NSDHL,NSUN2,PDGFA,RBPJ,RELA,SMO,SNAI1,SOS1,SOSTDC1,SOX18,SOX9,SPINK5,TGFB2,TGM3,TMEM79,TNFRSF19,TP63,TRPC4AP,VANGL2,WNT10A,ZDHHC21	TetrapodAncestor	94.8518
GO.Biological.Process	GO:0019058	viral.life.cycle	371	1.158073e-99	1.495883e-95	4.032029e-98	1.279490e+0	AAAS,ACE2,ALYREF,ANPEP,APOE,ATG16L1,ATG16L2,ATG5,AXL,CAV1,CAV2,CCL2,CCNT2,CCR5,CD209,CD46,CD55,CD80,CD81,CD86,CDC42,CDHR3,CDK1,CHMP1A,CHMP1B,CHMP2A,CHMP2B,CHMP3,CHMP4A,CHMP4B,CHMP4C,CHMP5,CHMP6,CHMP7,CLDN1,CLDN6,CLDN9,CLEC4G,CLEC4M,CR1,CR2,CTBP1,CTSB,CXADR,CXCR4,CXCR6,DEK,DHX9,DYNLT1,EEA1,EFNB2,EFNB3,EGFR,EIF2AK4,EIF2D,EIF3A,EIF3B,EIF3D,EIF3F,EIF3L,EPHA2,EPS15,F11R,FURIN,GAS6,GRK2,HAVCR1,HSP90AB1,HTR2A,IDE,IFIT1,IST1,ITCH,ITGA2,ITGA5,ITGAV,ITGB1,ITGB5,ITGB7,KPNA1,KPNA2,KPNA3,KPNA4,KPNA5,KPNA7,KPNB1,LDLR,LRRC15,LRSAM1,MCTS1,MON1B,MRC1,MVB12A,NCAM1,NDC1,NECTIN1,NECTIN2,NECTIN4,NEDD4L,NFIA,NMT2,NPC1,NUP107,NUP153,NUP155,NUP160,NUP188,NUP205,NUP214,NUP35,NUP37,NUP43,NUP50,NUP54,NUP58,NUP62,NUP85,NUP88,NUP98,NUPL2,PC,PCBP1,PCBP2,PCSK5,PDCD6IP,PIK3C2G,POM121,POM121C,RAB1A,RAB29,RAB43,RAB5A,RAB7A,RAE1,RANBP2,ROCK2,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL23,RPL23A,RPL24,RPL27,RPL28,RPL29,RPL3,RPL30,RPL31,RPL34,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL5,RPL6,RPL7,RPL7A,RPL8,RPLP0,RPLP2,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS17,RPS18,RPS20,RPS21,RPS23,RPS24,RPS25,RPS26,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS4X,RPS5,RPS6,RPS7,RPS8,RPSA,SCARB1,SCARB2,SERPINB3,SLC10A1,SLC1A5,SLC52A1,SLC52A2,SMARCB1,SUPT5H,TBC1D20,TFRC,THOC1,THOC2,THOC3,THOC5,THOC6,THOC7,TNFRSF14,TNFRSF4,TPR,TSG101,TYRO3,UBAP1,UBC,UBP1,USF1,USF2,USP6NL,UVRAG,VAMP8,VCP,VPS18,VPS28,VPS37B,VPS37C,VPS37D,VPS4A,VPS4B,VTA1,WWP1,WWP2,XPR1,ZNF639	TetrapodAncestor	94.8251
GO.Biological.Process	GO:0070304	positive.regulation.of.stress-activated.protein.kinase.signaling.cascade	372	1.218749e-99	1.574258e-95	4.231877e-98	1.291527e+0	AGER,ANKRD6,APP,ARL6IP5,BMP2,CCL19,CCL21,CCR7,CD27,CDC42,CTGF,DAB2IP,DAXX,DBNL,DKK1,DUSP15,DUSP19,DUSP22,DVL3,EDA2R,EDAR,EDN1,EIF2AK2,EPHA4,ERCC6,ERN1,ERN2,F2RL1,FGD2,FGF19,FLT4,FZD10,FZD4,FZD5,FZD7,FZD8,GADD45A,GADD45B,GADD45G,GDF6,HACD3,HAND2,HIPK2,HMGB1,HMGCR,HRAS,IL1B,IL26,INAVA,KARS,LEP,LTBR,LYN,MAP2K4,MAP2K7,MAP3K10,MAP3K11,MAP3K2,MAP3K21,MAP3K3,MAP3K4,MAP3K5,MAP3K6,MAP3K7,MAP3K9,MAP4K1,MAPK8IP3,MID1,MINK1,MUL1,NCF1,NOD1,NRK,OPRK1,PAK1,PDCD10,PKN1,PLCB1,PRMT1,PTK2B,PTPN1,PYCARD,RASGRP1,RASSF2,RB1CC1,RIPK1,RIPK2,ROR2,RPS3,SASH1,SDCBP,SEMA4C,SPAG9,SYK,TAOK1,TAOK2,TGFB2,TIAM1,TIRAP,TLR3,TLR4,TLR6,TLR9,TNF,TNFRSF11A,TNFRSF19,TNFSF11,TNIK,TPD52L1,TRAF2,TRAF4,TRAF6,UNC5CL,VANGL2,VEGFA,WNT16,WNT5A,WNT7A,WNT7B,XDH,ZC3H12A,ZNF622	TetrapodAncestor	94.8029
GO.Biological.Process	GO:0006979	response.to.oxidative.stress	373	2.952202e-99	3.813359e-95	1.022348e-97	1.210011e+0	ABCC2,ABL1,ADA,ADAM9,ADIPOQ,ADNP2,ADPRHL2,AIF1,AIFM1,AKR1B1,ALAD,ALDH3B1,ALS2,ANKRD2,ANKZF1,ANXA1,APEX1,APOA4,APOD,APOE,APP,APTX,AQP1,AREG,ARG1,ARL6IP5,ARNTL,ATF4,ATOX1,ATP13A2,ATRN,AXL,BAD,BAK1,BCL2,BECN1,BNIP3,BRF2,BTK,C19orf12,CA3,CAMKK2,CASP3,CAT,CBX8,CCL19,CCNA2,CCR7,CCS,CD36,CD38,CDK1,CDK2,CFLAR,CHD6,CHUK,COL1A1,CPEB2,CRK,CRYAB,CRYGD,CYBA,CYBB,CYCS,CYGB,CYP1B1,DAPK1,DGKK,DHCR24,DHRS2,DNM2,DPEP1,DUOX1,DUOX2,DUSP1,ECT2,EDN1,EEF2,EGFR,EGLN1,ENDOG,ENSG00000256632,EPAS1,EPX,ERCC1,ERCC2,ERCC3,ERCC6,ERCC6L2,ERCC8,ERO1A,ETS1,ETV5,EZH2,FABP1,FANCC,FER,FKBP1B,FOS,FOSL1,FOXO1,FXN,G6PD,GCLM,GLRX2,GNAO1,GPX2,GPX3,GPX7,GPX8,GSKIP,GSR,GSS,GSTP1,GUCY1B3,HAO1,HBA1,HBA2,HBB,HDAC2,HIF1A,HMOX1,HMOX2,HNRNPD,HP,HSF1,HTRA2,IL18BP,IL18RAP,IL6,IPCEF1,JAK2,JUN,KCNA5,KCNC2,KDM6B,KLF2,KLF4,KPNA4,KRT1,LCN2,LDHA,LONP1,LPO,LRRK2,MAP1LC3A,MAP3K5,MAPK1,MAPK3,MAPK8,MAPK9,MB,MBL2,MDM2,MELK,MGST1,MMP14,MMP3,MMP9,MPO,MPV17,MSRA,MSRB2,MSRB3,MTF1,MYB,NAPRT,NCF1,NCF2,NCF4,NDUFA12,NDUFA6,NDUFB4,NDUFS2,NDUFS8,NEIL1,NET1,NME2,NME8,NOS3,NOX4,NOX5,NQO1,NR4A2,NR4A3,NUDT1,NUDT2,OGG1,OXR1,P4HB,PARK7,PARP1,PAX2,PCGF2,PCNA,PDCD10,PDGFD,PDGFRB,PDK2,PDLIM1,PENK,PINK1,PKD2,PLEKHA1,PLK3,PML,PNKP,PNPT1,PPARGC1A,PPARGC1B,PPIF,PPP1R15B,PPP2CB,PPP5C,PRDX1,PRDX2,PRDX3,PRDX5,PRKAA1,PRKCD,PRKD1,PRKN,PRKRA,PRODH,PRR5L,PSEN1,PSIP1,PSMB5,PTGS1,PTK2B,PTPRK,PXDN,PXDNL,PXN,PYCR1,PYCR2,PYROXD1,RAD52,RBM11,RBPMS,RELA,RGS14,ROMO1,RPS3,RRM2B,RWDD1,S100A7,SCARA3,SCGB1A1,SDHAF3,SELENOK,SELENOP,SESN2,SETX,SGK2,SIRT1,SIRT2,SLC23A2,SLC25A24,SLC7A11,SLC8A1,SNCA,SOD1,SOD2,SOD3,SRC,SRXN1,STAR,STAT6,STAU1,STC2,STK24,STK26,STX4,TAT,TMEM161A,TNFAIP3,TOR1A,TP53,TP53INP1,TPO,TRAF2,TRPA1,TRPC6,TRPM2,TXN,TXN2,TXNDC2,TXNDC8,TXNIP,TXNL1,TXNRD1,UBE3A,UCN,UCP1,UCP2,UCP3,VKORC1L1,VNN1,VRK2,WNT16,WRN,XPA,XRCC1,ZC3H12A,ZNF277,ZNF580,ZNF622	TetrapodAncestor	94.4187
GO.Biological.Process	GO:0042633	hair.cycle	374	4.113155e-99	5.312962e-95	1.420578e-97	1.376091e+0	ACVR1B,ALX4,APCDD1,BCL2,CD109,CDC42,CDH3,CELSR1,CTNNB1,DKK1,DNASE1L2,DSG4,EDA,EDAR,EGFR,ERCC2,FGF10,FGF7,FGFR2,FOXE1,FOXN1,FOXQ1,FUZ,FZD3,FZD6,GNAS,GORAB,HDAC1,HDAC2,HOXC13,IGFBP5,INHBA,INTU,KRT14,KRT16,KRT17,KRT25,KRT27,KRT33B,KRT71,KRT83,KRT84,KRTAP4-5,KRTAP4-7,KRTAP4-8,KRTAP4-9,LAMA5,LDB2,LGR4,LGR5,LHX2,LRIG1,LRP4,MPZL3,NF1,NOTCH1,NSDHL,NSUN2,PDGFA,PPP1R13L,PTCH2,RBPJ,RELA,SMO,SNAI1,SNRPE,SOS1,SOSTDC1,SOX18,SOX9,SPINK5,TGFB2,TGM3,TMEM79,TNFRSF19,TP63,TRPC4AP,VANGL2,WNT10A,ZDHHC21	TetrapodAncestor	94.2747
GO.Biological.Process	GO:0003158	endothelium.development	375	6.611258e-99	8.539762e-95	2.277270e-97	1.361615e+0	ACVR2B,ACVRL1,AFDN,ARHGEF26,BMP4,BMPR2,CCM2,CD34,CLDN1,COL18A1,CSNK2B,CTNNB1,DLL1,DLL4,EDF1,ENG,EZR,F11R,F2RL1,FOXC2,GJA1,GJA4,GSTM3,HAPLN2,HEG1,HEY1,HEY2,ID1,JAG1,KDM6B,LAMA5,MARVELD2,MESP1,MET,MSN,MYADM,NOTCH1,NOTCH4,NRG1,NRP1,OVOL2,PDE2A,PDE4D,PDPN,PECAM1,PPP1R16B,PRKD2,PROX1,PTN,PTPRS,RAP1A,RAP1B,RAP2C,RAPGEF1,RAPGEF2,RAPGEF3,RBPJ,RDX,S1PR1,SCUBE1,SLC40A1,SMAD4,SOX17,SOX18,STARD13,STC1,STK4,TJP1,TJP2,TMEM100,TNMD,VEZF1,WNT7A,WNT7B	TetrapodAncestor	94.0686
GO.Biological.Process	GO:0032386	regulation.of.intracellular.transport	376	3.691235e-98	4.767968e-94	1.268077e-96	1.170759e+0	AAAS,ABCA2,ABLIM3,ACSM6,ADGRE2,ADIPOQ,ADORA2B,AGER,AGTR2,AKAP8L,AKT2,ANGPT1,ANK3,APC2,APOD,APP,ARF1,ARV1,ATG13,ATP13A2,ATPIF1,AXIN2,B3GAT3,BAG4,BAMBI,BAP1,BARD1,BCAP31,BCAS3,BCL3,BMP4,BMP6,BMP7,BMPR1A,BNIP3L,BRAF,BRSK2,BST2,BTBD9,C12orf4,C1QTNF3,C2CD5,C8orf4,CABP1,CAMK1,CAPN10,CCDC22,CCL19,CCL2,CD27,CD300A,CD36,CDC42,CDH1,CDH3,CDK1,CDK5,CDK5R1,CDKL2,CDKN1A,CEMIP,CHERP,CHMP3,CHP1,CHRM1,CIB1,CRYAA,CRYAB,CSF3,CSNK2A2,CTDSPL2,CYB5R1,CYFIP1,DAB2,DAB2IP,DACT1,DACT3,DDX58,DERL2,DERL3,DHX9,DMAP1,DMTN,DNAJC13,DNAJC27,DNM1,DNM1L,DTWD2,DYNC1H1,DYRK2,ECT2,EDA,EDAR,EDEM1,EDEM2,EGF,EGFR,ELMOD1,ENSG00000240045,ERBB2,ERBB4,EZR,F2,F2R,FAF1,FAM20B,FAM89B,FBXW11,FBXW7,FCER1G,FER,FERMT1,FES,FGF14,FGR,FIS1,FLNA,FMR1,FOXF1,FZD1,FZD5,FZD7,G3BP2,GAB2,GAS1,GAS6,GATA2,GCC2,GDI1,GLI3,GNAQ,GPHA2,GPR143,GREM1,GRIK5,GSK3A,GTSE1,HAP1,HAX1,HCLS1,HDAC3,HES1,HHAT,HMOX1,HNMT,HPCA,HPS4,HRC,HSP90AB1,HTRA2,ICE1,IFI27,IFNG,IFNL3,IGF1,IL10,IL12B,IL13,IL13RA2,IL18,IL18R1,IL1B,IL23A,IL4,IL6,INPP5K,IPO5,ITGAM,ITGAX,IWS1,JAK2,JUP,KANK1,KCNB1,KCNE1,KCNN3,KEAP1,KHDRBS1,KIF20B,KIF5B,LACRT,LCP1,LDLRAP1,LEP,LEPROT,LGALS9,LITAF,LRRK2,LYN,MAP1B,MAP2K2,MAPK1,MAPK14,MAPK3,MBTPS1,MDFI,MDM2,MFF,MIEF1,MIEF2,MIS18A,MLC1,MRGPRE,MSN,MTMR2,MTOR,MX2,MYBPC1,MYBPC3,MYLK2,MYO1C,NAPA,NCBP2,NDEL1,NEFH,NF1,NLGN1,NMUR1,NOL3,NOV,NPEPPS,NRG1,NUCB1,NUDT4,NUP153,NUP214,NUP54,NUP58,NUP62,NUS1,NUTF2,OAZ1,OAZ2,OGG1,OS9,PAK1,PARK7,PARL,PARP1,PARP10,PBLD,PCM1,PCNT,PDCD10,PDCD5,PDE2A,PDPK1,PEMT,PFN2,PIK3R1,PIK3R2,PINK1,PKD1,PKD2,PKIA,PKIG,PLAA,PLK3,PLN,POLR3A,PPP1R12A,PPP3CA,PRDX1,PREB,PRELID3A,PRKACA,PRKCD,PRKN,PRR5L,PSEN1,PSMB7,PSMD10,PSMD8,PTPN1,PTPN11,PTPN14,PTPN23,PYDC2,RAB21,RAB23,RAB29,RAB3GAP1,RAB5A,RAC2,RAP1A,RAP1B,RAPGEF3,RBCK1,RBM22,RBM4,RBPMS,RDX,REEP1,REEP2,REEP6,RHOU,RIMS1,RIMS3,RIMS4,RINT1,RIOK2,RIPOR1,RNF139,RNF31,RPL28,RUFY3,RUVBL1,SCFD1,SCP2,SEC16B,SEC24B,SELENOI,SEMA5A,SEPT5,SETD2,SFN,SFRP2,SFRP5,SH3GLB1,SH3TC2,SIAH3,SIRT1,SIRT4,SLC35D3,SLC51B,SLC9A3R1,SMAD4,SMO,SNAI2,SNCA,SNIP1,SNX12,SNX4,SORL1,SOX4,SP100,SPHK1,SPPL3,SRC,SREBF1,SREBF2,SRI,STARD7,STOM,STX18,STX1A,STX1B,STXBP1,STXBP2,STYK1,SUFU,SULF2,SVIP,SYK,SYN1,SYT11,TBC1D10C,TBC1D20,TDRD12,TENM1,TGFB1,TGFBR1,THOC2,THRA,TLR2,TLR3,TLR4,TLR9,TM9SF4,TMEM110,TMEM173,TMEM30B,TNF,TNFSF14,TNNC1,TNNT2,TOMM7,TONSL,TOR1A,TP53,TPR,TRIM28,TRIM58,TRIP6,TSGA13,TXN,U2AF1,U2AF2,UBAC2,UBE2D3,UBE2G2,UBE2J1,UBE2J2,UBE2L3,UBL5,UBR5,UGCG,UHMK1,UNC13B,USP36,VAMP2,VAMP8,VPS11,WBP11,WDR46,WDR75,WNT3A,WWC1,WWTR1,XPO4,XPO5,YIPF5,YOD1,YWHAE,ZBED3,ZBTB17,ZC3H12A,ZC3H3,ZDHHC8,ZIC1,ZPR1	TetrapodAncestor	93.3217
GO.Biological.Process	GO:0030279	negative.regulation.of.ossification	377	4.052978e-98	5.235232e-94	1.388656e-96	1.413046e+0	AHSG,AREG,AXIN2,BCL2,BCOR,CCL3,CCR1,CDK6,CHRD,CITED1,DKK1,FGF23,GDF10,GFRA4,GREM1,HAND2,HDAC4,HDAC7,HDAC8,HIF1A,ID1,ID3,IGFBP5,KREMEN1,KREMEN2,LIMD1,LRP4,LRP5,MEF2C,MEN1,MEPE,NBR1,NOCT,NOG,NOTCH1,OSTN,PTCH1,PTH,PTK2B,RANBP3L,RBPJ,RFLNB,RIOX1,RORB,SEMA4D,SFRP1,SKI,SMURF1,SOST,SOX9,SUFU,TGFB1,TMEM64,TNF,TNN,TPH1,TRPM4,TWIST1,TWIST2,UCMA	TetrapodAncestor	93.2811
GO.Biological.Process	GO:0007498	mesoderm.development	378	5.316583e-98	6.867430e-94	1.816780e-96	1.290397e+0	ACVR2A,ACVR2B,AMH,APELA,BMP4,BMP7,BMPR1A,BMPR2,BMX,BTK,CHRD,CITED2,CRB2,DAND5,DKK1,DLL3,EOMES,EPB41L5,EPHA2,ETS2,EXOC4,EXT1,EXT2,EYA1,EYA2,FGFR1,FGFR2,FOXC1,FOXC2,FOXF1,FOXH1,GDF11,GDF3,HAND1,HCK,HES7,HMGA2,IKZF1,IKZF3,INHBA,ITGA2,ITGA3,ITGA8,ITGB1,ITGB4,JAK2,KDM6A,KDM6B,KLF4,LEF1,LHX2,MATK,MESD,MESP1,MESP2,MEST,MSGN1,NF2,NOG,NR4A3,OSR1,OVOL1,PALB2,PAX2,POFUT2,POGLUT1,POU4F1,PRKACA,PRKAR1A,RPL38,SCX,SECTM1,SETD2,SIX2,SMAD2,SMAD4,SMO,SNAI1,SRF,T,TAL1,TBX1,TBX20,TBX3,TBX6,TCF15,TEAD2,TIE1,TLX2,TP63,TSPY2,TXNRD1,VEGFA,WLS,WNT11,WNT3,WNT3A,WNT5A,ZFP36L1,ZFPM2	TetrapodAncestor	93.1632
GO.Biological.Process	GO:0030178	negative.regulation.of.Wnt.signaling.pathway	379	5.564022e-98	7.187047e-94	1.896319e-96	1.248305e+0	AES,AMER1,AMER2,ANKRD6,APC,APC2,APCDD1,APOE,AXIN2,BARX1,BICC1,BMP2,CAV1,CBY1,CCND1,CDH2,CHD8,CITED1,CSNK1A1,CTNND1,CUL3,CXXC4,DAB2,DAB2IP,DACT1,DACT3,DKK1,DKK2,DKK3,DKK4,DRAXIN,DVL1,DVL3,EGR1,ENSG00000258864,FERMT1,FGF9,FOXO1,FUZ,FZD6,GLI3,GPC3,GRB10,GREM1,GSC,GSK3A,HDAC1,HECW1,HIC1,HMGXB4,IGFBP2,IGFBP4,IGFBP6,ISL1,JADE1,KLHL12,KREMEN1,KREMEN2,LATS1,LATS2,LEF1,LIMD1,LRP1,LRP4,LRP6,MAD2L2,MAPK14,MCC,MDFI,MESP1,MLLT3,NFATC1,NFATC4,NKD2,NKX2-5,NLK,NOG,NOTCH1,NOTUM,NPHP3,NPHP4,NXN,PFDN5,PRICKLE1,PRKN,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTPRO,RAPGEF1,RBMS3,RNF213,RNF43,ROR2,RPS27A,SCYL2,SDHAF2,SFRP1,SFRP2,SFRP4,SFRP5,SHISA2,SIAH2,SNAI2,SOST,SOSTDC1,SOX10,SOX17,SOX2,SOX9,STK4,TAX1BP3,TBX18,TLE1,TLE2,TMEM131L,TMEM64,TNN,TRABD2A,TRABD2B,TSC2,TSKU,UBC,WIF1,WNT11,WNT4,WNT5A,WWOX,WWTR1,ZNRF3	TetrapodAncestor	93.1434
GO.Biological.Process	GO:0032874	positive.regulation.of.stress-activated.MAPK.cascade	380	7.175734e-98	9.268896e-94	2.439183e-96	1.289607e+0	AGER,ANKRD6,APP,ARL6IP5,BMP2,CCL19,CCL21,CCR7,CD27,CDC42,CTGF,DAB2IP,DAXX,DBNL,DKK1,DUSP15,DUSP19,DUSP22,DVL3,EDA2R,EDAR,EDN1,EIF2AK2,EPHA4,ERCC6,ERN1,ERN2,F2RL1,FGD2,FGF19,FLT4,FZD10,FZD4,FZD5,FZD7,FZD8,GADD45A,GADD45B,GADD45G,GDF6,HACD3,HAND2,HIPK2,HMGB1,HMGCR,HRAS,IL1B,IL26,INAVA,KARS,LEP,LTBR,MAP2K4,MAP2K7,MAP3K10,MAP3K11,MAP3K2,MAP3K21,MAP3K3,MAP3K4,MAP3K5,MAP3K6,MAP3K7,MAP3K9,MAP4K1,MAPK8IP3,MID1,MINK1,MUL1,NCF1,NOD1,NRK,OPRK1,PAK1,PDCD10,PKN1,PLCB1,PRMT1,PTK2B,PTPN1,PYCARD,RASGRP1,RASSF2,RB1CC1,RIPK1,RIPK2,ROR2,RPS3,SASH1,SDCBP,SEMA4C,SPAG9,SYK,TAOK1,TAOK2,TGFB2,TIAM1,TIRAP,TLR3,TLR4,TLR6,TLR9,TNF,TNFRSF11A,TNFRSF19,TNFSF11,TNIK,TPD52L1,TRAF2,TRAF4,TRAF6,UNC5CL,VANGL2,VEGFA,WNT16,WNT5A,WNT7A,WNT7B,XDH,ZC3H12A,ZNF622	TetrapodAncestor	93.033
GO.Biological.Process	GO:0010611	regulation.of.cardiac.muscle.hypertrophy	381	8.802066e-98	1.136963e-93	2.984155e-96	1.478202e+0	AGT,AKAP13,AKAP6,ATP2B4,BMP10,CAMK2D,CAV3,CDK9,CTDP1,EDN1,ERRFI1,FOXO1,G6PD,GLRX3,GSK3A,HAMP,HAND2,IGF1,IL6ST,JARID2,LMCD1,LMNA,MEF2A,MLIP,MTOR,MTPN,NR4A3,P2RX4,PAK1,PARP1,PDE5A,PDE9A,PIN1,PPP3CA,PRKCA,RGS2,SLC9A1,SMAD4,TRIM63,TRPC3,TWF1	TetrapodAncestor	92.9443
GO.Biological.Process	GO:1903034	regulation.of.response.to.wounding	382	1.587485e-97	2.050554e-93	5.367943e-96	1.274524e+0	ABAT,ABCC8,ADAMTS18,ADRA2A,AGER,AJAP1,ANO6,ANXA1,APOE,APOH,ASIC2,BRAF,C1QTNF1,CASK,CAV1,CCL2,CD109,CD34,CD36,CD9,CERS2,CLASP1,CLASP2,CLEC4M,CNTF,CPB2,CRK,DMTN,DUSP10,EDN1,ENPP4,ENSG00000255439,EPHA4,F11,F12,F2,F2R,F2RL1,F3,F7,FAM46A,FCER1G,FGF2,FGG,FKBP1B,FOXA2,FOXC2,GJA1,GP1BA,HBEGF,HMGB1,HMGCR,HPSE,HRAS,HRG,IL10,INSL3,KANK1,KLF4,KLKB1,KNG1,KRT1,LBH,LRIG2,LYN,MTOR,MYLK,MYOD1,NDEL1,NOS3,NTRK3,PDGFA,PDGFB,PDPN,PHLDB2,PLAT,PLAU,PLEK,PLG,PLPP3,PPARD,PRKCA,PRKCD,PRKCE,PRKCQ,PRKG1,PROC,PROS1,PROZ,PTEN,PTPRS,REG3A,REG3G,RGMA,RREB1,RTN4R,SCARA5,SELP,SERPINB2,SERPINC1,SERPINE2,SERPING1,SOX15,SPAAR,SPP1,SRSF6,STAB2,STK24,STXBP5,SYK,TBXA2R,TC2N,TEC,TGFBR2,THBD,THBS1,TLR4,TMPRSS6,TNFAIP3,TNFRSF12A,TNR,TSPAN8,TXK,UBASH3B,USF1,VAV2,VIL1,VPS33B,VTN,WFDC1,WNT4,XBP1	TetrapodAncestor	92.6881
GO.Biological.Process	GO:0007369	gastrulation	383	2.605830e-97	3.365951e-93	8.788383e-96	1.261920e+0	ACVR2A,ACVR2B,AMOT,APELA,APLNR,ARID1A,ATOH8,BMP4,BMP7,BMPR1A,BMPR2,CDC73,CER1,CHRD,COL11A1,COL12A1,COL6A1,COL7A1,COL8A1,CRB2,CTNNB1,CUL3,DKK1,DLD,DUSP1,DUSP2,DVL1,ELF5,EOMES,EPB41L5,EPHA2,ETS2,EXOC4,EXT1,EXT2,EYA1,EYA2,FGFR2,FN1,FOXA2,FOXC1,FOXC2,FOXF1,FRS2,GATA6,GDF3,GSC,HAND1,HHEX,HIRA,HMGA2,HNF1B,HSBP1,INHBA,ITGA2,ITGA3,ITGA4,ITGA5,ITGA7,ITGA8,ITGAV,ITGB1,ITGB2,ITGB4,ITGB5,KDM6A,KDM6B,KIF16B,KLF4,LAMA3,LAMB1,LAMB3,LEF1,LEO1,LHX1,LRP5,LRP6,MEGF8,MESP1,MESP2,MIXL1,MKKS,MMP14,MMP15,MMP8,MMP9,MSGN1,NANOG,NF2,NOG,NPHP3,NR4A3,OTX2,PAF1,PAX2,POFUT2,POGLUT1,PRKACA,PRKAR1A,RIC8A,RNF2,RPS6,RTF1,SCX,SETD2,SFRP1,SIX2,SMAD2,SMAD4,SNAI1,SOX17,SOX2,SOX7,SRF,T,TAL1,TBX20,TBX6,TENM4,TGFBR2,TLX2,TXNRD1,VANGL2,VTN,WLS,WNT11,WNT3,WNT3A,WNT5A,WNT8B,ZBTB17	TetrapodAncestor	92.4729
GO.Biological.Process	GO:0010633	negative.regulation.of.epithelial.cell.migration	384	3.102456e-97	4.007442e-93	1.043605e-95	1.419167e+0	ACVRL1,ADAMTS9,ADGRB1,ADIPOR1,AGTR2,ANGPT2,ANGPT4,APOE,APOH,BMP10,CSNK2B,CXCL13,DAB2IP,DCN,DLL4,DUSP10,EVL,FGF2,GDF2,HDAC5,HMGB1,HRG,IL4,KLF4,KRIT1,MARVELD3,MCC,MEOX2,MMRN2,NOTCH1,PBLD,PDCD10,PFN2,PPARG,PTEN,PTPN23,PTPRG,PTPRM,PTPRR,RGCC,SEMA3A,SLIT2,SP100,SPRED1,STARD13,STC1,STRAP,SYNJ2BP,TACSTD2,TGFB1,THBS1,VASH1	TetrapodAncestor	92.3971
GO.Biological.Process	GO:0010799	regulation.of.peptidyl-threonine.phosphorylation	385	3.444960e-97	4.449855e-93	1.155806e-95	1.534565e+0	APP,BMP7,CAB39,CALM1,CALM2,CALM3,CEMIP,CHI3L1,DDIT4,DGKQ,DMTN,EGF,GSK3A,INPP5K,IRGM,MAPK1,PARD3,PLK1,PPEF2,PRKAG2,RIPK2,RPTOR,SIRT2,SMAD7,SPHK1,SPRED1,SPRED2,SPRY2,TGFB1,TNKS1BP1,TRIM6,TRPC5,TRPC6,WNK3,WNT5A	TetrapodAncestor	92.3517
GO.Biological.Process	GO:1901615	organic.hydroxy.compound.metabolic.process	386	4.939543e-97	6.380408e-93	1.652955e-95	1.198792e+0	ABCA1,ABCG1,ACAA2,ACAT2,ACER1,ACER2,ACER3,ACOT8,ACOX2,ACSS1,ACSS2,ADH1A,ADH1B,ADH1C,ADH4,ADH5,ADH6,ADH7,AGTR2,AKR1B1,AKR1B10,AKR1D1,ALDH1A1,ALDH1A3,ALDH1B1,ALDH2,ALDH3A2,ALDH3B1,ALDH3B2,ALOX15,AMACR,AOC2,APOA1,APOA2,APOA4,APOA5,APOB,APOBR,APOC1,APOE,APOF,APOL1,APOL2,APP,ARV1,ASIP,ATP8B1,AWAT2,BAAT,BCL2,BCO1,BTBD9,CACNA1H,CALM1,CAT,CEBPA,CEL,CELA3A,CELA3B,CES1,CETP,CFTR,CH25H,CHKA,CITED1,CLN6,CLN8,CNBP,COQ2,CPQ,CRYM,CTNS,CUBN,CYB5R1,CYB5R2,CYB5R3,CYP11A1,CYP11B1,CYP11B2,CYP17A1,CYP19A1,CYP1A1,CYP1B1,CYP24A1,CYP26A1,CYP26B1,CYP26C1,CYP27A1,CYP27B1,CYP27C1,CYP39A1,CYP46A1,CYP4A11,CYP4V2,CYP7A1,CYP8B1,D2HGDH,DBH,DCT,DDC,DDT,DEGS2,DGAT1,DGAT2,DHCR24,DHCR7,DHDDS,DHRS3,DHRS4,DIO1,DIO2,DIO3,DISP3,DPAGT1,DPM1,DPM2,DRD1,DRD2,DRD3,DRD4,DUOX1,DUOX2,EBPL,EPAS1,EPHX1,ERLIN1,ERLIN2,FDFT1,FDPS,FDX1,FDXR,FGF2,FGF23,FGFR1,FOXE1,G6PD,GALR2,GATA3,GBA,GBA2,GC,GCH1,GCNT4,GDE1,GDPD1,GK,GK3P,GK5,GOT1,GPR37,GRIN2A,HAND2,HAO1,HDC,HDLBP,HIF1A,HMGCR,HMGCS1,HMGCS2,HPRT1,HSD17B3,HSD17B4,HSD17B7,HSD3B7,HTR1A,IGF1,IL4,IMPA1,IMPA2,IMPAD1,INPP1,INPP4A,INPP4B,INPP5B,INPP5D,INPP5J,INPP5K,INSIG2,INSM1,IP6K1,IP6K3,IPMK,IPPK,ITPK1,ITPKA,ITPKB,ITPKC,IYD,LBR,LCAT,LDHA,LDHB,LDHC,LDLR,LDLRAP1,LEP,LEPR,LGMN,LIPE,LRAT,LRP5,LRTOMT,LSS,MAOA,MAOB,MBTPS1,MBTPS2,MECP2,MINPP1,MIOX,MOGAT2,MOXD1,MRS2,MTMR2,MTPN,MVD,NAPEPLD,NPC1,NPC1L1,NPC2,NPR1,NR0B2,NR1H4,NR4A2,NR5A2,NSDHL,NTSR1,NUDT4,NUS1,OCA2,OCRL,OSBP,OSBPL2,OSBPL3,OSBPL5,OSBPL9,PAH,PARK7,PARP9,PCK1,PDE1B,PDXK,PDXP,PECR,PER2,PFKFB2,PGP,PLB1,PLCB1,PLCB3,PLCB4,PLCD3,PLCE1,PLCG1,PLCG2,PLCH1,PLCH2,PLCZ1,PLPP6,PLTP,PMEL,PMVK,PNKD,PNMT,PNPLA4,PPARD,PPIP5K2,PRKAA1,PRKAA2,PRKAG2,PRKN,PSAT1,PTAFR,PTEN,RBP4,RDH10,RDH13,RDH14,RDH5,RDH8,RETSAT,RNF180,RPE65,RTL4,RXRA,SC5D,SCARB1,SCP2,SDR16C5,SGPP1,SLC27A2,SLC27A5,SLC34A1,SLC45A2,SLC5A3,SLC5A5,SLC6A3,SNCA,SNCAIP,SNCB,SNX17,SOAT1,SOAT2,SORD,SORL1,SPHK1,SPHK2,SPTLC1,SPTLC2,SQLE,SRD5A1,SRD5A2,SREBF1,SREBF2,STAR,SULT1A1,SULT1A2,SULT1A4,SULT1C4,SULT2A1,SULT2B1,SYNJ1,TG,TGFB2,TH,TKFC,TM7SF2,TPH1,TPH2,TPO,TRERF1,TRPC1,TTPA,TTR,TYR,TYRP1,VHLL,VLDLR	TetrapodAncestor	92.1952
GO.Biological.Process	GO:0035023	regulation.of.Rho.protein.signal.transduction	387	1.321667e-96	1.707197e-92	4.411362e-95	1.322515e+0	ABCA1,ABL1,ABR,ABRA,ADGRG1,ADRA1A,AKAP13,ALS2,APOA1,APOC3,APOE,ARAP3,ARHGAP35,ARHGAP42,ARHGDIA,ARHGDIB,ARHGEF1,ARHGEF10L,ARHGEF11,ARHGEF12,ARHGEF16,ARHGEF17,ARHGEF19,ARHGEF2,ARHGEF25,ARHGEF26,ARHGEF3,ARHGEF33,ARHGEF37,ARHGEF39,ARHGEF4,ARHGEF40,ARHGEF7,ARHGEF9,ARRB1,BCL6,BCR,CCDC125,COL3A1,CUL3,DLC1,DNMBP,ECT2,ECT2L,ENSG00000273167,EPS8L1,EPS8L2,F2R,F2RL1,F2RL3,FARP1,FGD1,FGD2,FGD3,FGD4,FGD5,FLCN,FLOT1,GPR17,GPR18,GPR20,GPR35,GPR4,GPR55,GPR65,ITGA3,ITGB1,ITSN1,ITSN2,KALRN,KANK1,KCTD13,LPAR1,LPAR4,LPAR6,MCF2,MCF2L,MCF2L2,MET,MYO9B,NET1,NGEF,NRP1,OBSCN,P2RY10,P2RY8,PDGFRB,PLEKHG1,PLEKHG2,PLEKHG3,PLEKHG4,PLEKHG4B,PLEKHG5,PLEKHG6,PLEKHG7,PREX1,RAC1,RAF1,RASGRF1,RASGRF2,RIPOR2,RIT2,ROBO1,RTN4R,SCAI,SOS1,SPATA13,STMN1,TIAM1,TIAM2,TNFAIP1,TRIO,VAV1,VAV2,VAV3	TetrapodAncestor	91.7677
GO.Biological.Process	GO:0032147	activation.of.protein.kinase.activity	388	3.486373e-96	4.503348e-92	1.160657e-94	1.199024e+0	ABL1,ACVR2B,ADAM9,ADCY2,ADCY3,ADCY4,ADCY5,ADCY8,ADNP,ADORA1,ADORA2B,ADRA2A,ADRA2B,ADRA2C,ADRB2,ALK,ANGPT1,ANGPT4,ARAF,ARRB1,AVPI1,BMP2,BMP4,BRAF,C1QTNF2,C5,CAB39,CARD10,CARD14,CARTPT,CCDC88A,CCL19,CD74,CD81,CDK1,CHI3L1,CHRNA3,COPS8,CRK,CRKL,CSPG4,CXCR4,DAB2IP,DAXX,DBF4B,DBNL,DGKQ,DLG1,DRD2,DRD4,DUSP19,DUSP6,DUSP7,DUSP9,DYNAP,ECT2,EFNA5,EGF,EGFR,EIF2AK2,EMP2,EPGN,EPO,ERCC6,ERN1,ERN2,ERP29,F2R,FAM58A,FGF1,FGF10,FGF13,FGF2,FRS2,GADD45A,GADD45B,GADD45G,GAS6,GHR,GNG3,GPRC5B,GREM1,GRM4,HACD3,HGF,HMGB1,IGF1,IKBKG,IL18,IL1B,INAVA,INS,IQGAP3,IRAK1,ITGA1,JAK2,KARS,LAMTOR2,LAMTOR3,LEP,LPAR1,LPAR3,LRRK2,MADD,MALT1,MAP2K2,MAP2K3,MAP2K4,MAP2K6,MAP2K7,MAP3K1,MAP3K10,MAP3K11,MAP3K12,MAP3K13,MAP3K14,MAP3K15,MAP3K19,MAP3K2,MAP3K21,MAP3K3,MAP3K4,MAP3K5,MAP3K6,MAP3K7,MAP3K7CL,MAP3K8,MAP3K9,MAP4K1,MAP4K3,MAP4K4,MAPK1,MAPK10,MAPK11,MAPK14,MAPK3,MAPK8IP3,MAPKAP1,MAPKAPK2,MAPKAPK3,MAPKAPK5,MARK2,MAS1,MINK1,MLST8,MOS,MTOR,MUC20,MUL1,NCKAP1L,NEK1,NEK4,NGF,NKX3-1,NOD1,NRG1,NRG3,NRK,NTF3,NTRK1,NTRK3,P2RX7,PAK1,PAK3,PAK4,PAK5,PARK7,PDE6H,PDGFB,PDGFC,PDPK1,PEA15,PIK3CA,PINK1,PKN1,PLA2G1B,PLCE1,PLCG1,PPP2R3C,PRKAA1,PRKACA,PRKACG,PRKAG2,PRKAR1A,PRKAR1B,PRKAR2B,PRKCD,PRKCZ,PRLR,PROK1,PROK2,PRR5,PSEN1,PTK2B,PTPN1,PTPN11,RAF1,RAP1A,RAPGEF1,RGCC,RICTOR,RIPK1,RIPK2,RIPK3,RPS27A,RPTOR,SAA1,SBK2,SHC1,SHC2,SLC11A1,SOD1,SPAG9,SPDYA,SRC,STK24,STK26,STRADA,STRADB,SYK,TAB1,TAB2,TAB3,TAOK1,TAOK2,TDGF1,TGFB2,TGFBR1,TGFBR2,THBS1,TIRAP,TLR3,TLR4,TLR6,TMEM189-UBE2V1,TNF,TNFRSF10A,TNFRSF10B,TNFSF11,TNFSF15,TNIK,TOM1L1,TP73,TPX2,TRAF2,TRAF4,TRAF6,TRAF7,TXN,UBC,UBE2N,UCN,VEGFA,WNK1,WNT11,WNT5A,WNT7B,ZFP91	TetrapodAncestor	91.3465
GO.Biological.Process	GO:0038127	ERBB.signaling.pathway	389	4.363986e-96	5.636961e-92	1.449090e-94	1.400291e+0	ABL1,AREG,BCAR1,BTC,CBL,CBLB,CPNE3,CSK,CUL5,DGKD,EFEMP1,EGF,EGFR,EPS15,EPS8,ERBB2,ERBB4,EREG,FAM83B,FES,GAB1,GAREM1,GRB2,GRB7,HBEGF,HRAS,IQGAP1,KIF16B,KRAS,MAPK1,MATK,MVP,NCK2,NRAS,NRG1,NRG2,NRG4,PAG1,PDPK1,PIGR,PIK3C2A,PIK3CA,PIK3R1,PLCE1,PLCG1,PRKCA,PTK2,PTK2B,PTPN11,PTPN12,PTPRR,PXN,RASSF2,REPS2,RPS27A,RPS6KA5,SHC1,SHC3,SLC30A10,SOCS5,SOS1,SOX9,SRC,STUB1,STYK1,TGFB1,UBC,VIL1	TetrapodAncestor	91.249
GO.Biological.Process	GO:0035567	non-canonical.Wnt.signaling.pathway	390	6.604583e-96	8.531140e-92	2.187472e-94	1.331411e+0	AGO1,AGO2,AGO3,AGO4,AP2A1,AP2A2,AP2B1,AP2M1,AP2S1,ARHGEF19,ARRB2,CALM1,CAMK2A,CDC42,CELSR1,CELSR2,CLTC,CTNNB1,DAAM1,DVL1,DVL3,FZD1,FZD10,FZD2,FZD3,FZD4,FZD5,FZD6,FZD7,FZD8,FZD9,GNAO1,GNG2,GPC4,GPC6,GRHL3,LEF1,MAGI2,MAP3K7,MOV10,NFATC1,NLK,PARD6A,PDE6A,PDE6B,PFN1,PLCB1,PLCB3,PPP3CA,PPP3CB,PPP3R1,PRICKLE1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTK7,RAC1,ROR2,RPS27A,RYK,SFRP1,SFRP2,SFRP4,SFRP5,SMURF1,SMURF2,TIAM1,TNRC6A,TNRC6B,TNRC6C,UBC,VANGL1,VANGL2,WNT1,WNT11,WNT4,WNT5A,WNT7A,WNT9B,ZNRF3	TetrapodAncestor	91.069
GO.Biological.Process	GO:0071456	cellular.response.to.hypoxia	391	6.873260e-96	8.878190e-92	2.270637e-94	1.304265e+0	ACAA2,ADAM8,ANGPT4,ANKRD1,AQP1,AQP3,BACH1,BAD,BCL2,BMP7,BNIP3,BNIP3L,BRIP1,CA9,CARD16,CASR,CCNA2,CCNB1,CFLAR,CITED2,CLCA1,COX4I2,CPEB1,CPEB2,CUL2,CYBB,DNMT3A,E2F1,EDN1,EGLN1,EGLN2,EGLN3,EGR1,EIF4EBP1,ELOB,ELOC,ENDOG,EP300,EPAS1,EPO,ERO1A,FABP1,FAM162A,FMN2,GATA6,GNGT1,HIF1A,HIF1AN,HIF3A,HIGD1A,HIPK2,HMOX1,HYOU1,IRAK1,KCND2,KCNK2,KCNK3,KCNMB1,LIMD1,LMNA,MDM2,MDM4,MGARP,MTOR,MYC,NDNF,NDRG1,NKX3-1,NOP53,NOTCH1,NPEPPS,OPA1,OPRD1,P4HB,PCK1,PDK3,PGK1,PINK1,PLK3,PMAIP1,PPARD,PPARGC1A,PRKAA1,PRKCE,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTEN,PTGIS,PTN,RBPJ,RGCC,RPS27A,S100B,SFRP1,SIRT1,SIRT2,SIRT4,SLC29A1,SLC8A1,SLC8A3,SLC9A1,SRC,STC1,STC2,SUV39H2,TBL2,TERT,TIGAR,TP53,TRPC6,TWIST1,UBC,UBE2D1,UBE2D2,UBE2D3,UBQLN1,UCN3,VEGFA,ZFP36L1	TetrapodAncestor	91.0517
GO.Biological.Process	GO:1901654	response.to.ketone	392	7.204535e-96	9.306098e-92	2.374005e-94	1.266371e+0	AACS,AANAT,ABCB4,ABCC2,ABHD2,ACACA,ADCY2,ADCY3,ADCY5,AGTR2,AIFM1,AKAP8,AKR1B1,AQP1,AR,ARG1,ATP2B1,AVP,AVPR1A,BAD,BCL2L1,BGLAP,CA9,CALR,CASP9,CATSPER1,CATSPER2,CATSPER4,CATSPERB,CATSPERD,CAV1,CBL,CCL19,CCL2,CCL21,CCND1,CCR7,CD38,CDC5L,CDK4,CDKN1A,CFLAR,CFTR,CLDN1,CLDN4,CPS1,CSNK2A1,CSNK2B,CYBA,CYBB,DCPS,DDIT4,DNMT3B,DSG1,DSG2,DUSP1,EDN1,EFNA5,EGFR,EIF4E,EIF4EBP1,ELK1,EPO,ERRFI1,F5,F7,FBXO32,FDX1,FIBIN,FOS,FOSB,FOSL1,FOXO1,FOXP2,GABRB1,GAS6,GBA,GHSR,GLB1,GNAI1,GNG2,GNRH1,HDAC8,HNRNPD,HNRNPU,HPCA,HSF1,IFNB1,IGFBP7,IL6,KCNJ11,KLF2,KLF4,KLF9,LARP1,MAOB,METTL21C,MSN,MSTN,NASP,NCOA1,NDOR1,NEFL,NKX3-1,NME1,NPAS4,NR1H3,NR3C1,NTRK3,OXT,OXTR,P2RY4,P2RY6,PARP1,PCK2,PCNA,PLN,PPARG,PRKAA1,PRKAA2,PRKCE,PSPH,PTAFR,PTGDR,PTGER2,PTGER4,PTN,RAMP2,RELA,ROCK2,RWDD1,SFRP1,SLIT2,SLIT3,SMYD3,SOX10,SPP1,SRC,SRD5A1,SRD5A2,SREBF1,STAR,TBXA2R,TGFB1,TGFB2,TH,THBS1,TLR2,TSPO,TXNIP,TYMS,UBE3A,UCN3,UGT3A2,USP8,UTS2,XRN1,YAP1	TetrapodAncestor	91.0312
GO.Biological.Process	GO:0034976	response.to.endoplasmic.reticulum.stress	393	1.090345e-95	1.408399e-91	3.583712e-94	1.293251e+0	ACADVL,ADD1,AIFM1,ALOX15,AMFR,ANKS4B,ANKZF1,APAF1,ASNA1,ASNS,ATF3,ATF4,ATF6,ATF6B,ATG10,ATP2A1,ATP6V0D1,ATXN3,AUP1,BAG6,BAK1,BAX,BCL2,BCL2L11,BHLHA15,BRSK2,CALR,CASP4,CCDC47,CCL2,CCND1,CEBPB,CHAC1,CREB3,CREB3L1,CREB3L2,CREB3L3,CREBRF,CTDSP2,CTH,CUL7,CXCL8,CXXC1,DAB2IP,DCTN1,DDRGK1,DDX11,DERL1,DERL2,DERL3,DNAJB11,DNAJB12,DNAJC10,DZIP3,EDEM1,EDEM2,EDEM3,EEF2,EIF2AK2,EIF2AK3,EIF2AK4,EIF2B5,EP300,ERLIN1,ERLIN2,ERN1,ERN2,ERO1A,EXTL1,EXTL2,EXTL3,FAF2,FAM129A,FBXO2,FBXO6,FGF21,FKBP14,FLOT1,FOXRED2,GET4,GFPT1,GOSR2,GSK3A,HDGF,HERPUD1,HM13,HSP90B1,HSPA5,HYOU1,IFNG,ITPR1,JKAMP,JUN,KDELR3,KIAA0368,KLHDC3,LMNA,MAN1B1,MAP3K5,MARCH6,MBTPS1,MBTPS2,MYDGF,NCK1,NCK2,NRBF2,OS9,P4HB,PARP16,PDIA3,PDIA4,PDIA6,PDILT,PIK3R1,PIK3R2,PLA2G4B,PLA2G6,PML,POMT1,POMT2,PPP1R15A,PPP1R15B,PPP2CB,PPP2R5B,PREB,PRKN,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PTPN1,RASGRF1,RASGRF2,RHBDD1,RNF103,RNF121,RNF139,RNF175,RNF185,RNF5,SCAMP5,SDF2L1,SEC61A1,SEC61A2,SEC61B,SEC61G,SEC62,SEC63,SEL1L,SELENOK,SERP1,SERP2,SESN2,SGTA,SHC1,SRPRA,SRPRB,SRPX,SSR1,STC2,STT3B,STUB1,SYVN1,TARDBP,TBL2,THBS1,THBS4,TLN1,TMBIM6,TMCO1,TMEM117,TMEM129,TMEM33,TMEM67,TMTC3,TMUB1,TMX1,TMX3,TMX4,TNFRSF10B,TOR1A,TP53,TPP1,TRAF2,TRIB3,TRIM13,TRIM25,TTC23L,TXNDC11,TXNDC5,UBE2G2,UBE2J1,UBE2J2,UBE4A,UBQLN1,UBXN4,UBXN6,UBXN8,UFC1,UFD1,UFL1,UGGT1,USP13,VAPB,VCP,WFS1,WIPI1,XBP1,YOD1,ZBTB17	TetrapodAncestor	90.8513
GO.Biological.Process	GO:0048771	tissue.remodeling	394	1.833976e-95	2.368947e-91	6.012555e-94	1.400558e+0	ACE,ACP5,ACVR2B,ACVRL1,ADRB2,AGT,AGTR2,ANXA1,ARG1,ATG5,AXL,BAK1,BAX,BGN,BMPR2,BSX,CAPN1,CAV1,CCR2,CHD7,CSPG4,CTNNB1,DBH,DLL4,EFNA4,ELF3,EPAS1,EPHA2,F2R,FGF10,FOXC1,FOXC2,GDF5,GPR55,HIF1A,HMGB1,HTR1B,IGFBP5,IHH,IL1A,IL23A,IL6,IL7,JAG1,LGR4,LIF,LIPA,LRP5,MDM2,MEF2C,MERTK,MMP14,NOL3,NOS3,NOTCH2,NOX4,P3H4,PLG,PTH,PTH1R,PTK2B,RAB3D,RAB7A,RAC1,RAC2,RASSF2,RBPJ,RSPO3,SEMA3C,SPP2,SRC,TGFB1,TGM2,THBS4,TNFSF11,TPH1,TPP1,TRAF6,WNT16,ZNF675	TetrapodAncestor	90.6254
GO.Biological.Process	GO:0050851	antigen.receptor-mediated.signaling.pathway	395	5.394302e-95	6.967820e-91	1.764005e-93	1.312473e+0	ABL1,BAX,BCAR1,BCL10,BCL2,BLK,BRAF,BTK,BTRC,CARD11,CD19,CD247,CD28,CD38,CD3D,CD3E,CD3G,CD79B,CHUK,CSK,CTLA4,CUL1,DENND1B,FBXW11,FOXP3,FYB1,FYB2,GATA3,GRAP2,HRAS,IFNG,IGLL1,IGLL5,IKBKB,IKBKG,INPP5D,ITK,KLHL6,LAT,LAT2,LAX1,LCK,LCP2,LYN,MALT1,MAP3K7,MAPK1,MEF2C,NCK1,NCKAP1L,NFAM1,NFATC2,NFKB1,PAG1,PAK1,PAK2,PAK3,PDE4B,PDE4D,PDPK1,PIK3CA,PIK3CD,PIK3R1,PIK3R2,PLCG1,PLCG2,PLEKHA1,PRKCB,PRKCQ,PRKD2,PSEN1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTPN22,PTPRJ,RBCK1,RELA,RFTN1,RFTN2,RIPK2,RNF31,RPS27A,SHB,SLA2,SPG21,SPPL3,SYK,TAB2,TEC,THEMIS,THEMIS2,THY1,TMEM189-UBE2V1,TNFRSF21,TRAF6,TRAT1,TXK,UBC,UBE2D1,UBE2D2,UBE2N,VAV3,ZAP70	TetrapodAncestor	90.1569
GO.Biological.Process	GO:0045684	positive.regulation.of.epidermis.development	396	1.020755e-94	1.318509e-90	3.329569e-93	1.638049e+0	ALOX15B,ATOH1,BMP4,CYP27B1,FOXC1,FOXN1,FST,GAL,H2AFY,H2AFY2,HPSE,IL20,KDF1,KRT17,MSX2,NCOA3,NME2,NOTCH1,OVOL2,PPARD,PRKCH,PTCH1,PTCH2,SFN,SFRP4,SULT2B1,TGFB2,TMEM79,TNF,TRADD,VDR,WNT10B,WNT5A	TetrapodAncestor	89.8799
GO.Biological.Process	GO:0002768	immune.response-regulating.cell.surface.receptor.signaling.pathway	397	1.148504e-94	1.483523e-90	3.736833e-93	1.233983e+0	ABI1,ABL1,ACTR2,ACTR3,ARPC1A,ARPC1B,ARPC2,ARPC4,ARPC5,BAG6,BAX,BCAR1,BCL10,BCL2,BLK,BRAF,BTK,BTRC,C3AR1,CALM1,CARD11,CD19,CD209,CD24,CD247,CD28,CD38,CD3D,CD3E,CD3G,CD40,CD79B,CDC42,CHUK,CLEC12B,CLEC4A,CLEC4C,CLEC4D,CLEC4E,CLEC6A,CLEC7A,CR1,CR2,CRK,CSK,CTLA4,CUL1,CYFIP1,CYFIP2,DENND1B,ELMO1,ELMO2,EP300,FBXW11,FCER1G,FCGRT,FCN1,FER,FFAR2,FGR,FOS,FOXP3,FYB1,FYB2,GAB2,GATA3,GPLD1,GPR32,GPR33,GRAP2,GRB2,HCK,HRAS,HSP90AB1,ICAM2,IFNG,IGLL1,IGLL5,IKBKB,IKBKG,INPP5D,ITK,JUN,KLHL6,KLRK1,KRAS,LAT,LAT2,LAX1,LCK,LCP2,LILRA4,LILRB2,LIMK1,LYN,MALT1,MAP2K4,MAP2K7,MAP3K1,MAP3K7,MAPK1,MAPK10,MAPK3,MAPK8,MAPK9,MEF2C,MS4A2,MUC1,MUC12,MUC13,MUC15,MUC20,MUC3A,MUC4,MUC5AC,MUC5B,MUC6,MUCL1,MYO10,MYO1C,MYO1G,NCK1,NCKAP1,NCKAP1L,NCR3,NFAM1,NFATC1,NFATC2,NFATC3,NFKB1,NR4A3,NRAS,PAG1,PAK1,PAK2,PAK3,PDE4B,PDE4D,PDPK1,PIGR,PIK3CA,PIK3CD,PIK3R1,PIK3R2,PLA2G6,PLCG1,PLCG2,PLD2,PLEKHA1,PLPP4,PPP3CA,PPP3CB,PPP3R1,PRKACA,PRKACG,PRKCB,PRKCD,PRKCE,PRKCQ,PRKD2,PSEN1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTK2,PTPN22,PTPRJ,RAC1,RAF1,RBCK1,RELA,RELB,RFTN1,RFTN2,RIPK2,RNF31,RPS27A,RPS6KA5,SHB,SHC1,SLA2,SNAI3,SOS1,SPG21,SPPL3,SRC,SYK,TAB1,TAB2,TAB3,TEC,THEMIS,THEMIS2,THY1,TMEM189-UBE2V1,TNFRSF21,TRAF6,TRAT1,TXK,UBC,UBE2D1,UBE2D2,UBE2N,VAV1,VAV2,VAV3,WASF2,WIPF2,WIPF3,YES1,ZAP70	TetrapodAncestor	89.8287
GO.Biological.Process	GO:0045662	negative.regulation.of.myoblast.differentiation	398	2.198818e-94	2.840213e-90	7.136214e-93	1.742438e+0	ANKRD2,BMP4,CCL17,CMTM5,CXCL10,CXCL14,DLL1,EID2B,GDF3,ID3,IL18,MBNL3,MSTN,NMRK2,NOTCH1,PPARD,PRICKLE1,SOSTDC1,SOX8,SOX9,TBX3,TGFB1,TNF	TetrapodAncestor	89.5466
GO.Biological.Process	GO:0019439	aromatic.compound.catabolic.process	399	2.652949e-94	3.426814e-90	8.588507e-93	1.223085e+0	AADAT,ACMSD,ADA,ADA2,ADPRM,AFMID,AGO1,AGO3,AGO4,AHCY,AICDA,ALDH1L1,ALDH1L2,AMBP,AOX1,APOBEC1,APOBEC2,APOBEC3A,APOBEC3C,APOBEC3F,APOBEC3G,APOBEC3H,ATM,CARNMT1,CARNS1,CASC3,CASP3,CDA,CECR2,CNOT1,CNOT10,CNOT11,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT8,CSDE1,CTIF,CYP1A1,CYP2A6,DBH,DCP2,DCPS,DDX5,DEDD2,DERA,DFFA,DFFB,DIO3,DIS3L2,DNA2,DNASE1,DNASE1L1,DNASE1L2,DNASE1L3,DNASE2,DPYD,DROSHA,DXO,EDC3,EDC4,EIF3E,EIF4A1,EIF4A2,EIF4A3,EIF4E,ENDOG,ENPP1,ENPP3,ENPP4,ENSG00000265303,ENSG00000282246,ENTPD2,ENTPD3,ENTPD4,ENTPD5,ENTPD6,ENTPD7,EPHX1,EPHX2,ERN1,ERN2,ETF1,EXOSC1,EXOSC10,EXOSC2,EXOSC3,EXOSC4,EXOSC5,EXOSC6,EXOSC7,EXOSC9,FAH,FBXO18,FEN1,FTCD,GALT,GDA,GSPT1,GSTZ1,H1F0,HAAO,HBS1L,HDC,HGD,HINT1,HMGB1,HMGB2,HMOX1,HMOX2,HNMT,HNRNPD,HPD,HPRT1,IDO1,IDO2,IL4I1,ISG20,ITPA,KHSRP,KMO,KPNA1,KPNB1,KYAT1,KYNU,LIN28A,LIN28B,LRTOMT,LSM1,LSM3,LSM5,LSM7,MAGOH,MAGOHB,MAOA,MAOB,METTL14,METTL3,MLH1,MOXD1,MRTO4,MTHFS,MTPAP,MUS81,NANOS2,NBAS,NCBP1,NCBP2,NEIL1,NEIL2,NOCT,NT5C,NT5C1A,NT5C1B,NT5C3A,NT5E,NT5M,NTHL1,NUDT1,NUDT12,NUDT15,NUDT16,NUDT18,NUDT4,NUDT5,NUDT7,NUDT9,OGG1,PABPC4,PAH,PAIP1,PAN2,PAN3,PAPD4,PARN,PATL1,PCBD1,PCID2,PDE10A,PDE12,PDE1A,PDE1B,PDE2A,PDE3A,PDE4A,PDE4B,PDE4D,PDE5A,PDE7B,PDE8A,PDE8B,PDE9A,PDXP,PELO,PNLDC1,PNP,PNPT1,PNRC1,PNRC2,POLR2D,POLR2G,PPP1R8,PPP2R2A,PRPF18,PYM1,QDPR,RBM8A,RC3H1,RNASEH1,RNASEH2A,RNASEH2B,RNASEH2C,RNASET2,RNH1,RNPS1,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL23,RPL23A,RPL24,RPL27,RPL28,RPL29,RPL3,RPL30,RPL31,RPL34,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL5,RPL6,RPL7,RPL7A,RPL8,RPLP0,RPLP2,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS17,RPS18,RPS20,RPS21,RPS23,RPS24,RPS25,RPS26,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS4X,RPS5,RPS6,RPS7,RPS8,RPSA,SAMD4A,SAMD4B,SAMHD1,SETMAR,SIDT2,SKIV2L2,SLC6A3,SLFN14,SMG1,SMG5,SMG6,SMG7,SMG8,SMPDL3A,SND1,SPO11,STK31,TAT,TATDN1,TDG,TDO2,THRAP3,TNKS1BP1,TTC37,TYMP,UGT1A1,UGT1A4,UNG,UPB1,UPF1,UPF2,UPF3A,UPP1,UROC1,VCP,WDR61,XDH,XRN1,ZC3H12A,ZCCHC11,ZCCHC6,ZFP36,ZFP36L1,ZFP36L2,ZHX2,ZPR1	TetrapodAncestor	89.4651
GO.Biological.Process	GO:0043434	response.to.peptide.hormone	400	3.793916e-94	4.900601e-90	1.225150e-92	1.204126e+0	AANAT,ABCC8,ADCY2,ADCY3,ADCY4,ADCY5,ADCY8,ADIPOQ,AGRP,AGT,AGTR1,AGTR2,AGTRAP,AHCYL1,AKT2,ANXA1,AP3S1,APC,APEX1,APOBEC1,APPL1,AREG,ARG1,ARID1B,ATP6AP1,ATP6V0A4,ATP6V0B,ATP6V0C,ATP6V0D1,ATP6V0D2,ATP6V0E1,ATP6V0E2,ATP6V1B1,ATP6V1B2,ATP6V1C1,ATP6V1C2,ATP6V1D,ATP6V1E1,ATP6V1E2,ATP6V1G1,ATP6V1G3,ATP6V1H,BAIAP2L2,BCAR1,BMP7,BRAF,BRIP1,BSG,BTG2,C2CD5,CA2,CACYBP,CAMK2A,CAPN10,CAT,CAV1,CAV2,CCL2,CCNA2,CDC5L,CDC6,CDK4,CDKN1B,CDO1,CFLAR,CITED1,COL1A1,CPEB1,CPEB2,CPS1,CREB1,CRHBP,CRHR1,CRHR2,CRK,CRY1,CSH1,CSK,CTGF,CYBA,CYBB,CYC1,CYFIP1,DENND4C,EDN1,EEF2K,EGR1,EGR2,EIF2B1,EIF2B3,EIF2B4,EIF2B5,EIF4EBP1,EIF6,ENPP1,ENSG00000278139,EPM2AIP1,EREG,ERRFI1,F7,FABP3,FER,FGF21,FOXC2,FOXO1,FOXO4,GAB1,GAL,GCGR,GCK,GGH,GH1,GH2,GHR,GHRHR,GHSR,GIP,GJA1,GLP1R,GLP2R,GNAI1,GNB2,GNG10,GNG11,GNG12,GNG13,GNG2,GNG3,GNG7,GNG8,GNRH1,GNRHR,GOT1,GPER1,GPLD1,GRB2,GSK3A,GSTP1,HADHA,HDAC5,HDAC9,HHEX,HSD11B2,HSF1,IDE,IGF1R,IGF2,IGFBP5,IL10,IL6,INHBB,INPP5K,INS,INSIG2,IQGAP1,IRS1,IRS2,IRS4,JAK2,JAK3,KAT2B,KHK,KL,LEP,LPIN1,LRP5,LRP6,LYN,MAPK1,MAPK3,MAS1,MAX,MC4R,MDM2,MEN1,MGARP,MTOR,NDEL1,NEFL,NFKB1,NKX6-1,NME2,NR4A1,NR4A2,NR4A3,OGT,OPRK1,OTC,OXT,OXTR,PAK1,PARP1,PCK1,PDK2,PDPK1,PFKFB1,PHEX,PHIP,PIK3C2A,PIK3CA,PIK3R1,PIK3R2,PIK3R3,PKLR,PKM,PLA2G1B,PLN,PNPT1,POR,PPARA,PPARG,PRKACA,PRKACG,PRKAR1A,PRKAR1B,PRKAR2B,PRKCD,PRKCI,PRKCZ,PRKDC,PRL,PRLH,PRLR,PTEN,PTK2,PTPN1,PTPRA,PXN,QDPR,RAB13,RAB31,RAB8A,RAP1B,RBBP4,RELA,RETN,RHOQ,RNF40,RPE65,SESN2,SESN3,SH2B2,SHC1,SIRT1,SLC25A33,SLC27A1,SLC2A1,SLC2A8,SLC30A10,SLC34A1,SLC9A1,SMARCC1,SOCS2,SOCS7,SOGA1,SORBS1,SOS1,SP1,SRC,SRD5A1,SRD5A2,SREBF1,SRSF4,SRSF5,SRSF6,STAR,STAT1,STC2,STXBP4,TBC1D4,TCIRG1,TEK,TFF1,TGFB1,TH,TIMP1,TIMP4,TLR2,TNFSF10,TRIB3,TRPV1,TSHR,TUSC5,UCP2,UCP3,UMODL1,UPRT,USF1,VAMP2,WDTC1,WNT1,XBP1,YWHAG,ZFP36L1,ZNF106	TetrapodAncestor	89.3098
GO.Biological.Process	GO:0007219	Notch.signaling.pathway	401	4.387941e-94	5.667903e-90	1.413442e-92	1.321732e+0	AGXT,ANGPT4,ANXA4,APH1A,APH1B,APP,ASCL1,ATOH1,BMP2,CDH6,CDK6,CDKN1B,CEBPA,CHAC1,CNTN1,CNTN6,DLL1,DLL3,DLL4,DNER,DTX1,DTX2,DTX3,DTX4,EP300,EPN1,FAT4,FCER2,FOXA1,FOXC1,FOXC2,GALNT11,GMDS,GOT1,HES1,HES5,HES7,HEY1,HEY2,HEYL,HHEX,HNF1B,IFT172,IFT74,ITCH,JAG1,JAG2,KAT2B,KCNA5,KRT19,MAML1,MAML2,MAML3,MDK,MESP1,MESP2,MIB1,MIB2,MYC,NCSTN,NEURL1,NEURL1B,NEUROD4,NLE1,NOTCH1,NOTCH2,NOTCH3,NOTCH4,NR0B2,NR1H4,ONECUT1,PERP,PGAM2,PLN,PSEN1,PSEN2,PSENEN,PTP4A3,RBPJ,RIPPLY1,RIPPLY2,RITA1,RPS27A,S1PR3,SEL1L,SNAI1,SNAI2,SNW1,SOX9,SPEN,SUSD5,TBX2,TGFB1,TGFBR2,TIMP4,TMEM100,TP63,UBC,WDR12,ZNF423	TetrapodAncestor	89.2466
GO.Biological.Process	GO:0006887	exocytosis	402	4.670548e-94	6.032947e-90	1.500733e-92	1.153801e+0	A1BG,A2M,ABCA12,ABCA13,ACPP,ACTN1,ACTN4,ACTR10,ACTR2,ADA2,ADAM8,ADGRE3,ADGRE5,ADGRG3,AGA,AGL,AGPAT2,AHSG,ALAD,ALB,ALDH3B1,ALDOA,ALOX5,ANK1,ANO6,ANPEP,ANXA3,ANXA5,AOC1,AP1M1,AP2A2,APAF1,APEH,APLP2,APOA1,APOH,APOOL,APP,ARFGEF2,ARG1,ARHGAP44,ARL8A,ARPC5,ASAH1,ATAD3B,ATP11A,ATP11B,ATP6AP2,ATP6V0C,ATP6V1D,ATP8A1,ATP8B4,B4GALT1,BLOC1S6,BPI,BRPF3,BRSK2,BST1,BST2,BTK,C16orf62,C1orf35,C3,C3AR1,C6orf120,CAB39,CADPS,CADPS2,CALM1,CALML5,CAND1,CANT1,CAP1,CAPN1,CAT,CBL,CCL3,CCL5,CCL8,CCR1,CCT2,CCT8,CD109,CD14,CD300A,CD33,CD36,CD44,CD47,CD53,CD55,CD58,CD59,CD63,CD68,CD9,CD93,CDA,CDC37L1,CDK13,CDK16,CDK5,CFP,CFTR,CHGA,CHI3L1,CHID1,CHIT1,CHP1,CHRNB4,CKAP4,CLEC12A,CLEC3B,CLEC4C,CLEC4D,CLU,CMTM6,COMMD3,COMMD9,CORO1A,COTL1,CPLX1,CPLX2,CPLX3,CPLX4,CPNE3,CPPED1,CR1,CRACR2A,CREG1,CRHBP,CRISP3,CRISPLD2,CSNK2B,CSTB,CTSA,CTSB,CTSC,CTSD,CTSH,CTSW,CTSZ,CXCL1,CXCR1,CXCR2,CYB5R1,CYB5R3,CYBA,CYBB,CYFIP1,CYSTM1,DBNL,DDOST,DDX3X,DEGS1,DERA,DGAT1,DIAPH1,DMTN,DNAJC13,DNASE1L1,DOC2A,DOC2B,DOCK2,DOK3,DPP7,DSC1,DSG1,DSN1,DSP,DYNC1H1,DYNC1LI1,DYNLL1,DYNLT1,EEF1A1,EEF2,EGF,ENDOD1,ENPP4,ENSG00000263620,EPX,EQTN,EXOC2,EXOC3,EXOC3L1,EXOC3L2,EXOC4,EXOC5,EXOC6,EXOC6B,EXOC7,EXOC8,F13A1,F5,F8,FABP5,FAF2,FAM3C,FAM49B,FCAR,FCER1G,FCN1,FERMT3,FGG,FGL2,FGR,FLG2,FLNA,FN1,FRK,FRMPD3,FTH1,FTL,FUCA1,FUCA2,GAA,GAS6,GCGR,GDI2,GGH,GLA,GLB1,GLIPR1,GM2A,GMFG,GNS,GOLGA7,GPR84,GRN,GSDMD,GSN,GSTP1,GTPBP2,GUSB,GYG1,HABP4,HAP1,HBB,HCK,HEBP2,HGF,HK3,HMGB1,HMOX2,HP,HPSE,HRG,HRNR,HSP90AB1,HSPA8,IGF1,IGF2,IGF2R,ILF2,IMPDH1,IQGAP1,ISLR,IST1,ITGA2B,ITGAM,ITGAV,ITGAX,ITGB2,ITIH3,ITIH4,JAGN1,JUP,KCNAB2,KCNB1,KLRF2,KNG1,KPNB1,KRT1,LAIR1,LAMTOR2,LAMTOR3,LAT,LAT2,LCN2,LEFTY2,LGALS3,LGALS3BP,LGI3,LILRB2,LIN7B,LIN7C,LLGL2,LRG1,LRMP,LRRC7,LYN,LYZ,MAGED2,MAN2B1,MANBA,MANF,MAPK1,MAPK14,MCEMP1,MGAM,MGST1,MIA3,MICAL3,MIF,MILR1,MLEC,MME,MMP25,MMP8,MMP9,MMRN1,MOSPD2,MPO,MS4A3,MVP,MYO1G,NAPRT,NBEAL2,NCKAP1L,NCSTN,NDUFC2,NFAM1,NFASC,NFKB1,NHLRC3,NIT2,NKD2,NLGN1,NME2,NPC2,NR4A3,NRAS,NSF,OLFM4,OLR1,ORM1,ORM2,ORMDL3,OSCAR,OSTF1,OTOF,P2RX7,PADI2,PAFAH1B2,PAK1,PCDH7,PCLO,PCYOX1L,PDAP1,PDGFA,PDGFB,PDXK,PECAM1,PF4,PFKL,PGAM1,PGLYRP1,PGM2,PGRMC1,PHACTR2,PIGR,PIK3C2A,PIK3CD,PIK3CG,PIP5K1C,PKM,PKP1,PLA2G3,PLAC8,PLAU,PLD1,PLEK,PLEKHO2,PLG,PNP,PPBP,PPIE,PPP3CB,PRCP,PRDX4,PRG2,PRG3,PRKCD,PROS1,PRSS12,PRSS2,PRSS3,PSAP,PSEN1,PSMA2,PSMB1,PSMB7,PSMC2,PSMC3,PSMD1,PSMD11,PSMD13,PSMD2,PSMD3,PSMD7,PTAFR,PTGES2,PTPRB,PTPRJ,PTPRN2,PTX3,PYCARD,PYGB,QPCT,QSOX1,RAB11B,RAB11FIP1,RAB11FIP2,RAB11FIP5,RAB14,RAB15,RAB18,RAB24,RAB26,RAB27A,RAB27B,RAB31,RAB37,RAB3D,RAB44,RAB4B,RAB5B,RAB6A,RAB7A,RAB8A,RAB8B,RAB9B,RABEPK,RAC1,RALA,RAP1A,RAP1B,RAP2B,RAP2C,RARRES2,RASGRP1,RETN,RHOG,RIMS1,RIMS3,RIMS4,RNASET2,RPH3A,RPH3AL,RSG1,S100A11,S100A12,S100A13,S100A7,S100A8,S100A9,S100P,SCAMP5,SCCPDH,SCFD1,SCFD2,SCG3,SCIN,SCRIB,SCRN1,SDCBP,SDF4,SELENOP,SELL,SELP,SEPT5,SERPINA1,SERPINA3,SERPINA4,SERPINB1,SERPINB10,SERPINB12,SERPINB3,SERPINB6,SERPING1,SIGLEC9,SIRPA,SIRPB1,SLC11A1,SLC15A4,SLC27A2,SLC2A3,SLC44A2,SLCO4C1,SLPI,SNAP23,SNAP25,SNAP29,SNAPIN,SNPH,SNX19,SOD1,SPP2,SRCIN1,SRP14,STBD1,STEAP2,STK11IP,STOM,STX11,STX19,STX1A,STX1B,STX3,STX4,STXBP1,STXBP2,STXBP5,STXBP5L,SURF4,SVIP,SYCN,SYK,SYNGR1,SYNGR2,SYNGR3,SYNJ1,SYT1,SYT10,SYT11,SYT13,SYT15,SYT17,SYT2,SYT4,SYT5,SYT6,SYT7,SYT8,SYT9,SYTL1,SYTL2,SYTL3,SYTL4,SYTL5,TAGLN2,TARM1,TBC1D10C,TCIRG1,TCN1,TEX264,TF,TGFB1,TGFB2,THBS1,TICAM2,TIMP1,TIMP2,TIMP3,TLN1,TLR2,TMBIM1,TMC6,TMED10,TMEM173,TMEM63A,TMEM79,TMX3,TNFAIP6,TNFRSF1B,TOLLIP,TOM1,TRAPPC1,TRIM72,TRIM9,TRPM2,TSG101,TTN,TTR,TUBB,TUBB4B,TXLNA,TXNDC5,UBR4,UNC13A,UNC13B,UNC13C,VAMP1,VAMP2,VAMP3,VAMP5,VAMP8,VAPA,VAT1,VCL,VCP,VEGFA,VEGFB,VEGFC,VEGFD,VMP1,VNN1,VPS11,VPS18,VPS33B,VPS41,VPS45,VTI1B,VWF,WDR1,XRCC5,XRCC6,YKT6,YPEL5,ZP4	TetrapodAncestor	89.2195
GO.Biological.Process	GO:0090100	positive.regulation.of.transmembrane.receptor.protein.serine/threonine.kinase.signaling.pathway	403	6.134080e-94	7.923391e-90	1.966102e-92	1.333009e+0	ACVR1B,ACVR2A,ACVR2B,ACVRL1,BMP10,BMP15,BMP2,BMP4,BMP5,BMP6,BMP7,BMP8A,BMP8B,BMPR1A,BMPR2,CDKN1C,CDKN2B,CITED1,CITED2,CRB2,CSNK2B,CYR61,DAB2,ENG,FBXL15,FERMT1,FGF9,FLCN,GATA4,GATA6,GDF1,GDF10,GDF11,GDF2,GDF3,GDF5,GDF6,GIPC1,GPC3,HES1,HES5,HIPK2,HSP90AB1,ING2,INHA,INHBA,INHBB,ITGA8,LEFTY1,LEFTY2,LRG1,MEN1,MSTN,MSX1,MSX2,MYOCD,NEO1,NOTCH1,PARP1,PELO,RBPJ,RBPMS,SDCBP,SMAD2,SMAD4,SNW1,SOX11,TGFB1,TGFB1I1,TGFB2,TGFBR1,THBS1,TTK,ZC3H3,ZNF423	TetrapodAncestor	89.1011
GO.Biological.Process	GO:0048640	negative.regulation.of.developmental.growth	404	1.022298e-93	1.320502e-89	3.268570e-92	1.331091e+0	ADRB2,ADRB3,ARHGAP4,BCL11A,BMP4,CAV3,CDK5,CDK5R1,CTDP1,DCC,DRAXIN,DUSP10,EPHA7,FGF13,FGFR3,FSTL4,FXN,G6PD,GAL,GJA1,GSK3A,IFRD1,JARID2,KCNK2,LGMN,MAG,MAPK11,MEIS1,MSTN,NOG,NRP1,OSTN,PAK1,PLAC8,PLXNA3,PTCH1,PTEN,PTK2,PTPRS,RAI1,RBP4,RNF6,RTN4,RTN4R,SEMA3A,SEMA3G,SEMA5A,SFRP1,SFRP2,SLC6A4,SOCS2,SPP1,STC2,STK4,TBX5,TGFBR2,TLL2,TNR,TP73,ULK2,WNT3,WNT3A,WNT5A,WWC1,WWC2,WWC3	TetrapodAncestor	88.8793
GO.Biological.Process	GO:0001704	formation.of.primary.germ.layer	405	1.171616e-93	1.513376e-89	3.736732e-92	1.297489e+0	ARID1A,ATOH8,BMP4,BMP7,BMPR1A,BMPR2,CDC73,CHRD,COL11A1,COL12A1,COL6A1,COL7A1,COL8A1,CRB2,CTNNB1,DKK1,DUSP1,DUSP2,ELF5,EOMES,EPB41L5,EPHA2,ETS2,EXOC4,EXT2,EYA1,EYA2,FGFR2,FN1,FOXC1,FOXC2,FOXF1,GATA6,HAND1,HMGA2,HNF1B,HSBP1,INHBA,ITGA2,ITGA3,ITGA4,ITGA5,ITGA7,ITGA8,ITGAV,ITGB1,ITGB2,ITGB4,ITGB5,KDM6A,KDM6B,KIF16B,KLF4,LAMA3,LAMB1,LAMB3,LEF1,LEO1,LHX1,MESP1,MESP2,MIXL1,MMP14,MMP15,MMP8,MMP9,MSGN1,NANOG,NF2,NOG,NR4A3,PAF1,PAX2,POFUT2,PRKACA,PRKAR1A,RTF1,SCX,SETD2,SIX2,SMAD2,SNAI1,SOX17,SOX2,SOX7,SRF,T,TAL1,TBX20,TBX6,TLX2,TXNRD1,VTN,WLS,WNT11,WNT3,WNT3A,WNT5A	TetrapodAncestor	88.8201
GO.Biological.Process	GO:0046889	positive.regulation.of.lipid.biosynthetic.process	406	1.594201e-93	2.059229e-89	5.071994e-92	1.497702e+0	ABCG1,ABHD6,ACSL3,ADGRF5,ANXA1,APOA1,APOA4,APOA5,APOE,AVP,AVPR1A,BMP6,CCDC3,CNEP1R1,CREB1,CREBL2,CYR61,DGAT2,FABP3,FGF1,GPLD1,HSD17B13,HTR2A,HTR2B,HTR2C,IFNG,IL1B,INS,LDLR,MID1IP1,MLXIPL,MTOR,NR1D1,NR1H2,NR1H3,NR1H4,NSMAF,PLA2G6,PLIN5,POR,PPARGC1A,PRKAA1,PRKCD,RGN,SCARB1,SIRT4,SLC45A3,SMPD2,SMPD3,SORBS1,SREBF1,STAR,STARD4,TNF,TNFRSF1A,WNT4,ZP3	TetrapodAncestor	88.6863
GO.Biological.Process	GO:0051403	stress-activated.MAPK.cascade	407	1.817815e-93	2.348072e-89	5.769218e-92	1.384423e+0	ADORA2B,AGT,BTRC,CASR,CCL19,CCM2,CDC42EP5,CHUK,CRKL,CRYAB,CUL1,DAB2IP,DAXX,DBNL,DUSP9,ERCC6,ERN1,ERN2,FBXW11,GPS1,HACD3,IKBKB,IKBKG,IRAK1,IRAK4,LGALS9,MAP2K4,MAP2K7,MAP3K10,MAP3K11,MAP3K12,MAP3K13,MAP3K2,MAP3K21,MAP3K5,MAP3K6,MAP3K7,MAP3K8,MAP3K9,MAP4K1,MAP4K3,MAPK1,MAPK10,MAPK14,MAPK3,MAPK8,MAPK8IP1,MAPK8IP3,MAPK9,MAPKAPK2,MINK1,MUL1,NFKB1,NOD1,NPHS1,NRK,PKN1,PTGER4,PTPN1,RIPK1,RIPK2,ROR2,RPS27A,SH2D3A,SH2D3C,SPAG9,SYK,TAB1,TAB2,TAB3,TAOK2,TMEM189-UBE2V1,TNF,TNFRSF19,TNFSF11,TNIK,TNIP2,TRAF6,TRIB1,UBC,UBE2N,WNT5A,WNT7B,ZFP36,ZFP36L1	TetrapodAncestor	88.6293
GO.Biological.Process	GO:0052547	regulation.of.peptidase.activity	408	2.351861e-93	3.037899e-89	7.445831e-92	1.205848e+0	A2M,A2ML1,ACER2,ADORA2A,ADRM1,AGT,AHSG,AIFM1,AKIRIN2,AMBP,ANOS1,ANTXR1,APAF1,APLP2,APP,AQP1,ARL6IP1,ARL6IP5,ARRB1,ARRB2,ASPH,ATP13A2,ATR,AVP,BAD,BAK1,BAX,BCAP31,BCL10,BCL2L10,BCL2L11,BCL2L12,BCL2L13,BID,BIRC2,BIRC3,BIRC5,BIRC6,BLID,BST2,C3,C4A,C4B,C5,CARD16,CARD17,CARD18,CASP1,CASP2,CASP3,CASP8,CASP9,CAST,CAV1,CCK,CD109,CD27,CD44,CDKN2D,CIDEB,CLPX,COL28A1,COL4A3,COL6A3,COL7A1,CPAMD8,CR1,CRADD,CRB2,CRIM1,CRYAB,CSNK2A1,CST6,CST7,CSTA,CSTB,CTGF,CTSH,CYCS,CYFIP2,CYR61,DAP,DAPK1,DDRGK1,DDX3X,DHCR24,DLC1,DNAJB6,DPEP1,EFNA1,EFNA3,EGLN3,EIF2AK3,ENSG00000177359,ENSG00000214776,EPHA4,EPHA7,EPPIN,EPPIN-WFDC6,F2R,F3,FABP1,FADD,FAM162A,FAS,FASLG,FBLN1,FETUB,FIS1,FN1,FURIN,GAPDH,GAS6,GPC3,GPER1,GRAMD4,GSN,HERPUD1,HGF,HIP1,HIP1R,HMGB1,HMSD,HRG,HSF1,HTRA2,IFI27,IFI6,IFT57,IGBP1,IL6,ITIH1,ITIH3,ITIH4,ITIH6,JAK2,KARS,KIAA0141,KLF4,KNG1,LAMP3,LCK,LCN1,LEF1,LGALS9,LPA,LXN,LYN,MAP3K5,MAPK14,MAPK3,MAPT,MDM2,MEFV,MICAL1,MMP14,MMP9,MTCH1,MUL1,MYC,NAIP,NEK5,NGF,NGFR,NKX3-1,NLE1,NLRC4,NLRP1,NLRP2,NLRP7,NOD1,NOL3,NRDC,PAK2,PAPLN,PARK7,PAX2,PCID2,PCSK1N,PDCD2,PDCD5,PDCD6,PERP,PI15,PI16,PI3,PICALM,PIDD1,PIH1D1,PINK1,PMAIP1,PML,POR,PPARG,PPM1F,PRDX3,PRDX5,PRELID1,PROS1,PSMA3,PSME1,PSME2,PSME3,PSMF1,PTTG1,PTTG2,PYCARD,PZP,R3HDML,RAF1,RAG1,RECK,RENBP,REST,RFFL,RIPK1,RIPK2,RNF34,ROBO1,RPS27L,RPS3,RPS6KA1,RPS6KA3,S100A8,S100A9,SEMG1,SEMG2,SERPINA1,SERPINA10,SERPINA11,SERPINA12,SERPINA3,SERPINA4,SERPINA5,SERPINA6,SERPINA7,SERPINA9,SERPINB1,SERPINB10,SERPINB11,SERPINB12,SERPINB13,SERPINB2,SERPINB3,SERPINB4,SERPINB5,SERPINB6,SERPINB7,SERPINB8,SERPINB9,SERPINC1,SERPIND1,SERPINE2,SERPINE3,SERPING1,SERPINH1,SERPINI1,SERPINI2,SFN,SFRP2,SH3RF1,SIAH2,SIRT1,SLPI,SNCA,SORL1,SOX2,SOX7,SPINK1,SPINK13,SPINK14,SPINK4,SPINK5,SPINK6,SPINK7,SPINK9,SPINT1,SPINT3,SPINT4,SPOCK1,SPOCK2,SPOCK3,SPP2,SRC,SSPO,ST18,TBC1D10A,TFAP2B,TFPI,TFPI2,THBS1,TIMP1,TIMP2,TIMP3,TIMP4,TNF,TNFAIP8,TNFRSF10A,TNFRSF10B,TNFRSF10C,TNFRSF10D,TNFRSF1B,TNFSF10,TNFSF14,TNFSF15,TP63,TRADD,TRAF2,TRIAP1,UBXN1,UCHL5,UMODL1,USP14,USP47,VCP,VEGFA,VIL1,VTN,WDR35,WFDC1,WFDC10A,WFDC12,WFDC13,WFDC2,WFDC3,WFDC5,WFDC6,WFDC8,WFIKKN1,WNT3A,WNT9A,XDH,XIAP,YWHAE	TetrapodAncestor	88.5174
GO.Biological.Process	GO:1901888	regulation.of.cell.junction.assembly	409	3.137249e-93	4.052385e-89	9.908031e-92	1.375829e+0	ABL1,ACE,ACE2,ACVRL1,AGT,APOD,ARHGAP6,BCAS3,CAMSAP3,CAV1,CBFB,CLASP1,CLASP2,CLDN1,CLDN5,COL16A1,DAPK3,DLC1,DMTN,EFNA5,EPB41L5,EPHA3,FLOT1,FMN1,FZD5,GJA1,GPBAR1,GPM6B,GREM1,HRG,IKBKB,IQGAP1,MACF1,MMP14,MYO1C,NPHP1,NPHP4,NRP1,OCLN,PHLDB2,PKP2,PPM1F,PRKACA,PRKCH,PTEN,PTK2,PTPRJ,RAC1,RAP1A,RAP1B,RAPGEF1,RAPGEF2,RCC2,RHOD,ROCK2,RUNX1,S100A10,SDC4,SFRP1,SLC9A1,SNAI1,SNAI2,SRC,TEK,THBS1,THY1,TJP1,TNF,VEGFA,WNT4	TetrapodAncestor	88.3923
GO.Biological.Process	GO:0002429	immune.response-activating.cell.surface.receptor.signaling.pathway	410	3.517877e-93	4.544042e-89	1.108303e-91	1.253695e+0	ABI1,ABL1,ACTR2,ACTR3,ARPC1A,ARPC1B,ARPC2,ARPC4,ARPC5,BAG6,BAX,BCAR1,BCL10,BCL2,BLK,BRAF,BTK,BTRC,C3AR1,CARD11,CD19,CD209,CD247,CD28,CD38,CD3D,CD3E,CD3G,CD79B,CDC42,CHUK,CLEC4A,CLEC4C,CLEC4D,CLEC4E,CLEC6A,CLEC7A,CR1,CR2,CRK,CSK,CTLA4,CUL1,CYFIP1,CYFIP2,DENND1B,ELMO1,ELMO2,EP300,FBXW11,FCER1G,FCN1,FFAR2,FGR,FOXP3,FYB1,FYB2,GATA3,GPLD1,GPR32,GPR33,GRAP2,GRB2,HCK,HRAS,HSP90AB1,ICAM2,IFNG,IGLL1,IGLL5,IKBKB,IKBKG,INPP5D,ITK,KLHL6,KLRK1,KRAS,LAT,LAT2,LAX1,LCK,LCP2,LIMK1,LYN,MALT1,MAP3K7,MAPK1,MAPK3,MEF2C,MUC1,MUC12,MUC13,MUC15,MUC20,MUC3A,MUC4,MUC5AC,MUC5B,MUC6,MUCL1,MYO10,MYO1C,MYO1G,NCK1,NCKAP1,NCKAP1L,NCR3,NFAM1,NFATC2,NFKB1,NR4A3,NRAS,PAG1,PAK1,PAK2,PAK3,PDE4B,PDE4D,PDPK1,PIK3CA,PIK3CD,PIK3R1,PIK3R2,PLA2G6,PLCG1,PLCG2,PLD2,PLEKHA1,PLPP4,PRKACA,PRKACG,PRKCB,PRKCD,PRKCE,PRKCQ,PRKD2,PSEN1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTK2,PTPN22,PTPRJ,RAC1,RAF1,RBCK1,RELA,RELB,RFTN1,RFTN2,RIPK2,RNF31,RPS27A,RPS6KA5,SHB,SLA2,SNAI3,SPG21,SPPL3,SRC,SYK,TAB1,TAB2,TAB3,TEC,THEMIS,THEMIS2,THY1,TMEM189-UBE2V1,TNFRSF21,TRAF6,TRAT1,TXK,UBC,UBE2D1,UBE2D2,UBE2N,VAV1,VAV2,VAV3,WASF2,WIPF2,WIPF3,YES1,ZAP70	TetrapodAncestor	88.3426
GO.Biological.Process	GO:0061572	actin.filament.bundle.organization	411	4.916999e-93	6.351288e-89	1.545325e-91	1.559419e+0	ACTN1,ACTN4,ADD1,AIF1,ARRB1,BAIAP2L2,CDC42,CORO1B,CUL3,DMTN,DPYSL3,EPS8,ESPN,ESPNL,EZR,FMN2,FSCN1,FSCN3,HSP90B1,ITGB5,KCTD13,LCP1,LIMA1,MARCKS,MYO1B,NEDD9,PAWR,PDXP,PHACTR1,PLS1,PLS3,PTK2B,RFLNA,RFLNB,RHOD,SORBS1,SPIRE1,SPIRE2,SRC,SRF,TNFAIP1,USH1C,ZYX	TetrapodAncestor	88.1971
GO.Biological.Process	GO:0090288	negative.regulation.of.cellular.response.to.growth.factor.stimulus	412	5.215448e-93	6.736794e-89	1.635144e-91	1.274596e+0	ABL1,ADAMTS12,ADAMTSL2,ADGRA2,AGT,AGTR2,ASPN,BAMBI,BCL9L,BMPER,CASK,CAV1,CAV2,CD109,CER1,CFLAR,CHRD,CHRDL1,CHST11,CIDEA,CTDSPL2,CXCL13,DAB2IP,DAND5,DCN,DKK1,DNM2,EID2,FAM129B,FAM89B,FBN2,FSTL3,FUZ,FZD1,GATA3,GDF3,GLG1,GPC1,GREM1,GREM2,HFE2,HHEX,HIPK2,HRG,HSPA5,HTRA1,HTRA3,HTRA4,LDLRAD4,LEMD2,LEMD3,MMRN2,MTMR4,NBL1,NOG,NOTCH1,ONECUT1,PBLD,PDCD6,PDPK1,PIN1,PMEPA1,PRDM16,PTPN1,RASL11B,RBPMS2,RPS27A,SFRP1,SFRP2,SHISA2,SIRT1,SKI,SKIL,SKOR2,SLIT2,SMAD2,SMAD7,SMURF1,SMURF2,SNX6,SOST,SOSTDC1,SPRY1,SPRY2,STRAP,STUB1,SULF2,TGFB1,TGFB1I1,TGFBR1,TGFBR2,THBS1,TMPRSS6,TRIM33,UBC,VWC2,VWC2L,WFIKKN1,WNT1,WNT4,WNT5A,XDH	TetrapodAncestor	88.1715
GO.Biological.Process	GO:0042476	odontogenesis	413	7.188508e-93	9.285396e-89	2.248280e-91	1.297516e+0	ACP4,ACVR2B,ADAMTS5,ALPL,AMELX,AQP1,AQP3,AQP5,AQP6,AXIN2,BAX,BCL11B,BCL2L11,BCOR,BGLAP,BMP2,BMP4,BMP7,BMPR1A,BSG,CA2,CEMP1,CNNM4,COL1A1,COL1A2,CSF3R,CTNNA1,CTNNB1,DLX3,EDA,EDAR,FAM20A,FAM20C,FGF10,FGF4,FGFR2,FOXC1,FOXO1,GLI2,GLI3,HAND1,HAND2,HDAC1,HDAC2,HTRA1,ID3,INHBA,ITGB4,JAG2,LAMA5,LAMB1,LEF1,LHX8,LRP4,LRP6,MMP20,MSX1,MSX2,NECTIN1,NF2,NFIC,NKX2-3,OSR1,PAM,PAX9,PERP,PITX2,PPARA,ROGDI,RUNX2,SCN5A,SLC24A4,SLC34A1,SMO,SOSTDC1,SSUH2,STIM1,TBX1,TGFB2,TNC,TP63,TRAF6,TUFT1,TWIST1,WDR72,WNT10A,WNT6	TetrapodAncestor	88.0322
GO.Biological.Process	GO:0051101	regulation.of.DNA.binding	414	1.309598e-92	1.691608e-88	4.086009e-91	1.329032e+0	ACD,AGER,ANKRD33,BCL3,CALM2,CALM3,CDCA5,CEBPG,CSNK2B,CTNNB1,DDRGK1,DOT1L,E2F1,EDF1,EGF,ERCC2,ERCC4,FOXC1,GATA3,GZMA,HABP4,HAND1,HAND2,HDAC2,HDAC8,HES1,HEY1,HEY2,HIPK2,HJURP,HMGA2,HMGB1,HMGB2,HMOX1,ID1,IFNG,IGF1,IRF4,ISL1,ITGA2,JAK2,JUN,KDM1A,KLF4,LEF1,LHX2,LIF,MAD2L2,MAPK8,MDFI,MMP9,MSX1,MSX2,MYOCD,NEUROD1,NME1,NSD1,PARK7,PARP1,PER2,PINX1,PITX2,POU4F1,PPARA,PPARG,PRKN,PSEN1,RB1,RSF1,SIRT2,SKI,SMO,SOX11,SP100,SRI,SUMO1,SUMO3,TAF1,TGFB1,TNKS,TRAF6,TRIM28,TRIM6,TWIST1,TXN,WAPL,WFIKKN1,WNT3A,ZBTB7C,ZFP90,ZNF462,ZNF593,ZNF675	TetrapodAncestor	87.7717
GO.Biological.Process	GO:0030258	lipid.modification	415	2.029206e-92	2.621125e-88	6.315965e-91	1.238139e+0	A3GALT2,ABCD1,ABCD2,ABCD3,ABO,ACAA2,ACAD10,ACADL,ACADM,ACADS,ACADVL,ACAT1,ACAT2,ACOT8,ACOX2,ACOX3,ACOXL,ACSM1,ADH7,ADIPOQ,ADIPOR1,ADIPOR2,AGK,ALDH3A2,AMACR,AUH,B4GALNT1,B4GALNT2,BDH2,BPNT1,BTC,CD19,CD28,CD80,CD86,CERK,CPT1A,CPT1B,CPT1C,CPT2,CRAT,CROT,CYGB,CYP1A1,CYP2C8,CYP4A22,CYP4V2,DECR1,DGKA,DGKB,DGKD,DGKE,DGKG,DGKI,DGKQ,DGKZ,ECH1,ECHDC1,ECHDC2,ECHS1,ECI1,ECI2,EFR3A,EFR3B,EGF,EGFR,EHHADH,ENSG00000249967,ENSG00000278139,EPHX2,ERBB2,ERBB4,EREG,ETFA,ETFB,FA2H,FAM126A,FGF1,FGF10,FGF16,FGF17,FGF18,FGF19,FGF2,FGF20,FGF22,FGF23,FGF3,FGF4,FGF6,FGF7,FGF9,FGFR1,FGFR2,FGFR3,FGFR4,FRS2,GAB1,GBGT1,GCDH,GLT6D1,GRB2,HACL1,HADHA,HADHB,HAO1,HAO2,HBEGF,HGF,HSD17B4,ICOS,IMPA1,IMPA2,IMPAD1,INPP1,INPP5B,INPP5D,INPP5J,INPP5K,IP6K1,IRS1,IRS2,IVD,KITLG,KL,LCAT,LCK,LEP,MAPK14,MCAT,MECR,MET,MTM1,MTMR1,MTMR2,MTMR3,MTMR6,MTMR8,NDUFAB1,NRG1,NRG2,NRG4,OCRL,PDGFA,PDGFB,PDGFRB,PECR,PEX13,PEX2,PEX7,PHYH,PI4K2A,PI4K2B,PI4KB,PIK3AP1,PIK3C2A,PIK3C2B,PIK3C2G,PIK3C3,PIK3CA,PIK3CD,PIK3CG,PIK3R1,PIK3R2,PIK3R5,PIK3R6,PIKFYVE,PIP4K2A,PIP4K2B,PIP4K2C,PIP5K1A,PIP5K1B,PIP5K1C,PIP5KL1,PLA2G7,PLPP1,PLPP2,PLPP3,PLPP4,PLPP5,PLPP6,PLPPR1,PLPPR2,PLPPR4,PLPPR5,POR,PPARD,PPARG,PPARGC1A,PRKAA1,PTEN,PTPN11,SACM1L,SCP2,SESN2,SLC25A17,SLC27A2,SLC35C1,SMG1,SOAT1,SOAT2,SPHK1,SPHK2,ST3GAL2,ST3GAL4,SYNJ1,SYNJ2,TMEM150A,TMEM55A,TMEM55B,TRAT1,TTC7B,VAV1,ZFYVE21	TetrapodAncestor	87.5815
GO.Biological.Process	GO:0030879	mammary.gland.development	416	2.359673e-92	3.047990e-88	7.326898e-91	1.277117e+0	ABCB4,AKT2,APLN,AR,AREG,ARG1,ARHGAP35,ARHGAP5,ATP7B,B4GALT1,BCL2L11,BMP4,BSX,BTRC,CAPN1,CAV1,CCL11,CCND1,CDO1,CEBPB,CREB1,CSF1,CSF1R,CYP19A1,DDR1,DHODH,EGF,ELF3,ELF5,EPHA2,ERBB4,ESR1,FASN,FGF10,FGFR2,FOXF1,GHRHR,GLI2,GLI3,GPAT4,HIF1A,ID2,IGFBP5,IRF6,IRS2,ITGA2,JAK2,KALRN,KDM5B,LATS1,LBH,LEF1,LRP5,MAPK1,MSX1,MSX2,NCOA1,NEURL1,NME1,NOTCH4,NRG1,NRG3,OXTR,PAM,PGR,PML,PRL,PRLR,PTCH1,PYGO2,SCRIB,SERPINC1,SLC29A1,SLC6A3,SMO,SOCS2,SOSTDC1,SOX9,SRC,STAT6,TBX2,TBX3,TDGF1,TGFB1,TGFBR2,TNFRSF11A,TNFSF11,TPH1,UMPS,UPRT,USF2,VDR,VEGFA,WNT3,WNT3A,WNT4,WNT5A,WNT7B,XDH,ZNF703	TetrapodAncestor	87.516
GO.Biological.Process	GO:0022612	gland.morphogenesis	417	2.442354e-92	3.154789e-88	7.565440e-91	1.284795e+0	AR,AREG,ARG1,BCL2,BMP4,BMP7,BSX,BTRC,CAPN1,CAV1,CCL11,CDC42,CEBPB,CRIP1,CSF1,CSF1R,CUL3,DDR1,DUOX2,EDA,EDAR,EGFR,ELF3,EPHA2,ESR1,ESRP2,FEM1B,FGF10,FGF7,FGFR1,FGFR2,FOXA1,FRS2,GLI2,GLI3,ID4,IGFBP5,IL6,KDM5B,LAMA5,LRP5,MSN,MSX2,NFIB,NKX2-3,NKX3-1,NOG,NOTCH1,NRG3,NRP1,PGR,PLAG1,PLXNA1,PLXND1,PML,POLB,PROP1,PROX1,PTCH1,RARG,RPS6KA1,SCRIB,SEMA3A,SEMA3C,SERPINB5,SFRP1,SLC9A3R1,SOSTDC1,SOX9,SRC,STAT6,TBX2,TBX3,TGFB1,TGFB2,TGFBR2,TGM2,TNC,TNF,TP63,VDR,WNT4,WNT5A	TetrapodAncestor	87.501
GO.Biological.Process	GO:0072012	glomerulus.vasculature.development	418	2.775626e-92	3.585276e-88	8.577216e-91	1.778503e+0	ACTA2,ANGPT1,ANGPT2,AQP1,BMP4,CD34,EGR1,FOXC2,GPR4,HES1,NOTCH1,NOTCH3,OSR1,PDGFB,PDGFRB,PECAM1,TCF21,TEK	TetrapodAncestor	87.4455
GO.Biological.Process	GO:0016567	protein.ubiquitination	419	7.222211e-92	9.328930e-88	2.226475e-90	1.150513e+0	ABTB1,ABTB2,AMFR,ANAPC1,ANAPC11,ANAPC13,ANAPC16,ANAPC2,ANAPC4,ANAPC5,ANKIB1,ARIH1,ARRB1,ARRB2,ARRDC4,ASB1,ASB10,ASB11,ASB12,ASB13,ASB14,ASB16,ASB17,ASB18,ASB5,ASB6,ASB7,ASB9,ATG3,AURKA,AURKB,BACH1,BACH2,BARD1,BCL10,BCL2,BCOR,BFAR,BIRC2,BIRC3,BIRC5,BIRC6,BLMH,BMI1,BRAP,BRCA1,BTBD11,BTBD18,BTBD2,BTBD3,BTBD6,BTBD9,BTRC,CACUL1,CAND1,CBFB,CBL,CBLB,CBLC,CBLL1,CBX8,CCDC22,CCIN,CCNB1,CCNB1IP1,CCNF,CDC16,CDC20,CDC23,CDC26,CDC27,CDC34,CDC42,CDC73,CDK1,CHFR,CISH,CNOT4,COMMD1,CRBN,CUL1,CUL2,CUL3,CUL4A,CUL5,CUL7,CUL9,DCAF1,DCAF10,DCAF11,DCAF12,DCAF15,DCAF16,DCAF4,DCAF5,DCAF6,DCAF7,DCAF8,DCST1,DDB1,DDB2,DERL1,DET1,DTX1,DTX2,DTX3,DTX3L,DTX4,DZIP3,E4F1,ELOB,ELOC,ENSG00000258677,ENSG00000259529,ENSG00000277971,EPAS1,ERCC8,FANCF,FANCL,FBXL12,FBXL13,FBXL15,FBXL16,FBXL19,FBXL2,FBXL22,FBXL3,FBXL5,FBXL6,FBXL7,FBXL8,FBXO10,FBXO15,FBXO17,FBXO18,FBXO2,FBXO21,FBXO22,FBXO24,FBXO27,FBXO3,FBXO30,FBXO31,FBXO32,FBXO33,FBXO4,FBXO40,FBXO41,FBXO44,FBXO45,FBXO6,FBXO7,FBXW10,FBXW11,FBXW12,FBXW2,FBXW5,FBXW7,FBXW8,FBXW9,FEM1A,FEM1B,FEM1C,FZR1,G2E3,GAN,GID4,HACE1,HECTD1,HECTD2,HECTD3,HECTD4,HECW1,HECW2,HERC1,HERC2,HERC4,HIF1A,HIF3A,HIST1H2BL,HIST1H2BM,HIST1H2BN,HIST1H2BO,HLTF,IPP,ITCH,KBTBD11,KBTBD12,KBTBD13,KBTBD2,KBTBD3,KBTBD4,KBTBD6,KBTBD7,KBTBD8,KCTD13,KCTD21,KCTD6,KCTD9,KDM2B,KEAP1,KLHDC7A,KLHDC7B,KLHDC8A,KLHL1,KLHL12,KLHL13,KLHL14,KLHL15,KLHL17,KLHL18,KLHL2,KLHL20,KLHL21,KLHL22,KLHL24,KLHL25,KLHL28,KLHL29,KLHL3,KLHL30,KLHL32,KLHL33,KLHL34,KLHL35,KLHL36,KLHL38,KLHL4,KLHL42,KLHL5,KLHL7,KLHL8,KLHL9,LEO1,LMO7,LNPEP,LNX1,LONRF1,LONRF2,LONRF3,LRR1,LRRC41,LRSAM1,LTN1,MAD2L1,MAEA,MALT1,MARCH1,MARCH10,MARCH11,MARCH2,MARCH3,MARCH4,MARCH5,MARCH6,MARCH8,MARCH9,MDM2,MDM4,MED10,MED11,MED18,MED20,MED21,MED27,MED30,MED31,MED7,MED8,MGRN1,MIB1,MIB2,MID2,MKRN1,MKRN2,MPHOSPH8,MSL2,MUL1,MYCBP2,MYLIP,NAIP,NEDD4L,NEDD8,NEURL1,NEURL1B,NEURL2,NEURL3,NHLRC1,NLRC4,NOSIP,NPEPPS,NSMCE1,NUB1,OS9,OTULIN,PAF1,PCGF1,PCGF2,PCGF3,PCGF5,PCNA,PCNP,PDZRN3,PELI1,PELI2,PELI3,PEX10,PEX12,PEX2,PEX5,PHC1,PINK1,PJA1,PJA2,PLK1,PPIL2,PRKDC,PRKN,PRPF19,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTTG1,RAB40B,RAB40C,RAD18,RAG1,RAG2,RBCK1,RC3H1,RC3H2,RCHY1,RFFL,RFWD2,RFWD3,RING1,RLIM,RMND5A,RMND5B,RNF10,RNF103,RNF11,RNF114,RNF115,RNF121,RNF122,RNF123,RNF125,RNF126,RNF128,RNF13,RNF130,RNF133,RNF135,RNF138,RNF139,RNF14,RNF144A,RNF144B,RNF145,RNF146,RNF149,RNF152,RNF166,RNF167,RNF168,RNF169,RNF170,RNF175,RNF180,RNF181,RNF182,RNF183,RNF185,RNF19B,RNF2,RNF20,RNF208,RNF213,RNF216,RNF217,RNF220,RNF222,RNF24,RNF25,RNF26,RNF31,RNF34,RNF38,RNF4,RNF40,RNF41,RNF43,RNF44,RNF5,RNF6,RNF7,RNF8,RNFT1,RPS27A,RRAGA,RTF1,RUSC1,RYBP,SASH1,SH3RF1,SH3RF2,SHARPIN,SIAH1,SIAH2,SIRT1,SKP2,SMURF1,SMURF2,SOCS1,SOCS2,SOCS3,SOCS4,SOCS5,SOCS6,SOCS7,SPOP,SPOPL,SPSB1,SPSB3,STUB1,SYVN1,TAF1,THOP1,TMEM129,TMEM189,TMEM189-UBE2V1,TNFAIP1,TNFAIP3,TNKS,TNKS2,TOPORS,TPP2,TRAF2,TRAF3,TRAF6,TRAF7,TRAIP,TRIM11,TRIM13,TRIM2,TRIM21,TRIM22,TRIM23,TRIM24,TRIM25,TRIM28,TRIM32,TRIM33,TRIM36,TRIM37,TRIM38,TRIM39,TRIM5,TRIM58,TRIM6,TRIM62,TRIM63,TRIM68,TRIM71,TRIM72,TRIM8,TRIM9,TRIML1,TRIML2,TRIP12,TRPC4AP,TSG101,TSPAN17,TTC3,TULP4,UBA1,UBA6,UBA7,UBC,UBE2A,UBE2C,UBE2D1,UBE2D2,UBE2D3,UBE2E1,UBE2E2,UBE2E3,UBE2F,UBE2G2,UBE2H,UBE2I,UBE2J1,UBE2J2,UBE2L3,UBE2L5P,UBE2L6,UBE2M,UBE2N,UBE2Q1,UBE2Q2,UBE2QL1,UBE2R2,UBE2S,UBE2T,UBE2V1,UBE2V2,UBE2W,UBE3A,UBE3D,UBE4A,UBOX5,UBR1,UBR2,UBR4,UBR5,UHRF1,UHRF2,UNKL,USP22,USP7,USP9X,UVSSA,VCP,VHLL,WDR61,WDTC1,WSB1,WWP1,WWP2,WWTR1,XIAP,ZBTB16,ZC3HC1,ZFP91,ZNF598,ZNF645,ZNF738,ZNRF1,ZNRF2,ZNRF3,ZNRF4,ZSWIM2,ZYG11A,ZYG11B	TetrapodAncestor	87.0302
GO.Biological.Process	GO:0050727	regulation.of.inflammatory.response	420	8.895068e-92	1.148976e-87	2.735657e-90	1.227654e+0	A2M,ABR,ACE2,ACP5,ADA,ADAM8,ADAMTS12,ADCYAP1,ADIPOQ,ADORA1,ADORA2A,ADORA2B,AGER,AGT,AGTR1,AHSG,ANXA1,APOA1,APOD,APOE,ASH1L,BAP1,BCL6,BCR,BIRC2,BIRC3,BRD4,BST1,BTK,C1QA,C1QB,C1QBP,C1QC,C1QTNF12,C1QTNF3,C3,C3AR1,C4A,C4B,C4BPA,C4BPB,C5,C5orf30,C6,C7,C8A,C8B,C8G,C9,CALCRL,CASP1,CASP4,CASP5,CCL3,CCL5,CCR2,CCR7,CD19,CD28,CD46,CD47,CD55,CD59,CD6,CD81,CDK19,CFH,CFHR1,CFHR2,CFHR4,CFHR5,CFI,CFP,CHID1,CLU,CNR1,CNR2,CPB2,CPN1,CPN2,CR1,CR2,CREB3L3,CX3CL1,CX3CR1,CYP19A1,DDT,DHX9,DROSHA,DUOXA1,DUOXA2,DUSP10,EDNRB,EGFR,ENSG00000173366,ESR1,ETS1,F12,F2,FABP4,FANCA,FCER1G,FEM1A,FFAR2,FFAR3,FFAR4,FNDC4,FOXF1,FOXP3,GATA3,GBA,GGT1,GHSR,GPER1,GPR17,GPRC5B,GPSM3,GSTP1,HCK,HGF,IDO1,IL10,IL12B,IL15,IL17A,IL17B,IL17F,IL17RA,IL17RB,IL17RC,IL18,IL1B,IL1R1,IL1R2,IL1RL1,IL1RL2,IL2,IL20,IL20RB,IL21,IL22RA2,IL23A,IL33,IL4,IL6,IL6ST,INS,ISL1,ITGA2,JAK2,KARS,KLF4,KLKB1,KRT1,LBP,LDLR,LEP,LPL,LYN,MAPK13,MAPK14,MAS1,MCPH1,MEFV,METRNL,MGLL,MGST2,MMP26,NDFIP1,NFKB1,NLRC3,NLRP1,NLRP10,NLRP6,NLRP7,NLRX1,NOS2,NOV,NPY5R,NR1D2,NR1H3,NR1H4,NT5E,OSM,OSMR,OTUD7A,OTULIN,PARK7,PBK,PDE2A,PER1,PGLYRP1,PGLYRP2,PHB,PIK3AP1,PIK3CG,PLA2G2A,PLA2G7,PPARA,PPARD,PPARG,PRKCD,PROC,PROS1,PSMB4,PTGER3,PTGER4,PTGIS,PYDC2,RELA,RHBDD3,RICTOR,S100A12,S100A8,S100A9,SAA1,SCGB1A1,SELE,SEMA7A,SERPING1,SETD6,SHARPIN,SHPK,SMPDL3B,SNCA,SNX4,SOCS3,SOCS5,SPN,SUSD4,TAC1,TBC1D23,TEK,TGM2,TICAM1,TLR10,TLR2,TLR3,TLR4,TLR6,TLR9,TNF,TNFAIP3,TNFAIP6,TNFAIP8L2,TNFRSF11A,TNFRSF1A,TNFRSF1B,TNFSF11,TNFSF18,TNIP1,TYRO3,USP18,VAMP8,VPS35,VTN,WFDC1,WNT5A,XCL1,XIAP,ZC3H12A,ZP3,ZYX	TetrapodAncestor	86.9397
GO.Biological.Process	GO:0097191	extrinsic.apoptotic.signaling.pathway	421	8.987186e-92	1.160875e-87	2.757422e-90	1.418680e+0	ACVR1B,APPL1,BAD,BAK1,BAX,BCL2,BCL2A1,BCL2L1,BCL2L10,BCL2L11,BCL2L2,BCL2L2-PABPN1,BID,BLOC1S2,CASP2,CASP3,CASP8,CASP9,CD27,CD70,CIB1,CRADD,DAB2IP,DAPK1,DAXX,DCC,DDX3X,DDX47,DEDD,DEDD2,EYA2,FADD,FAS,FASLG,FGFR3,G0S2,GSK3A,HIPK1,IFNG,IL12A,IL1A,IL1B,IL2,IL33,IL4,IL6R,INHBA,ITGAV,JAK2,KIAA0141,KITLG,LCN2,MKNK2,MLLT11,NF1,NGF,P2RX7,PARP2,PDPK1,PIK3R1,PML,RAF1,RIPK1,RNF41,SGPP1,TGFB1,TGFB2,TLR3,TNF,TNFRSF10A,TNFRSF10B,TNFRSF12A,TNFRSF1A,TNFRSF1B,TNFSF12,TRADD,TRAF2,WWOX	TetrapodAncestor	86.9352
GO.Biological.Process	GO:0072073	kidney.epithelium.development	422	2.123870e-91	2.743403e-87	6.500955e-90	1.232255e+0	ACAT1,ADAMTS16,AHI1,AQP1,AQP11,ARG2,BASP1,BCL2,BMP2,BMP4,BMP7,BMPER,CALB1,CAT,CD24,CD34,CER1,CITED1,CTNNB1,DCHS1,DLG1,DLL1,EFNB2,EPCAM,EPHA4,EPHA7,EYA1,FAT4,FGF1,FGF2,FGFR1,FGFR2,FMN1,FOXC1,FOXC2,FOXJ1,GATA3,GDF11,GDNF,GLI3,GPC3,GREM1,GZF1,HES1,HES5,HEYL,HNF1B,IQGAP1,JAG1,KIF26B,KLF15,KLHL3,LAMA5,LGR4,LHX1,MAGI2,MEF2C,MTSS1,MYC,MYO1E,NOG,NOTCH1,NPHS1,NPHS2,OSR1,PAX2,PAX8,PBX1,PECAM1,PKD1,PKD2,PODXL,POU3F3,PROM1,PTCH1,PTPRO,RARA,RARB,RET,ROBO2,SDC4,SFRP1,SIM1,SIX2,SLIT2,SMAD2,SMAD4,SMAD5,SMAD7,SMO,SOX8,SOX9,SPRY1,TACSTD2,TCF21,TFAP2B,TGFB1,UMOD,WNK4,WNT1,WNT11,WNT4,WNT6,WNT7B,WNT9B	TetrapodAncestor	86.5617
GO.Biological.Process	GO:0001942	hair.follicle.development	423	4.414249e-91	5.701885e-87	1.347963e-89	1.373452e+0	ACVR1B,ALX4,APCDD1,BCL2,CD109,CDC42,CELSR1,CTNNB1,DKK1,DNASE1L2,DSG4,EDA,EDAR,EGFR,ERCC2,FGF10,FGF7,FGFR2,FOXE1,FOXN1,FOXQ1,FUZ,FZD3,FZD6,GNAS,GORAB,HDAC1,HDAC2,HOXC13,IGFBP5,INHBA,INTU,KRT17,KRT25,KRT27,KRT71,KRT84,LAMA5,LDB2,LGR4,LGR5,LHX2,LRP4,NF1,NOTCH1,NSDHL,NSUN2,PDGFA,RBPJ,RELA,SMO,SNAI1,SOS1,SOSTDC1,SOX18,SOX9,SPINK5,TGFB2,TGM3,TMEM79,TNFRSF19,TP63,TRPC4AP,VANGL2,WNT10A,ZDHHC21	TetrapodAncestor	86.244
GO.Biological.Process	GO:0070482	response.to.oxygen.levels	424	5.051498e-91	6.525020e-87	1.538920e-89	1.202540e+0	ABAT,ABCB4,ACAA2,ACTN4,ACVRL1,ADA,ADAM8,ADIPOQ,ADORA1,ADSL,AGER,AGTRAP,AHCY,AIFM1,AJUBA,ALAD,ALDH3A1,ANGPT2,ANGPT4,ANGPTL4,ANKRD1,APAF1,APOLD1,AQP1,AQP3,ARNT2,ASCL2,ATM,ATP1B1,ATP6AP1,ATP6V0D1,ATP6V1G1,BACH1,BAD,BCL2,BECN1,BIRC2,BMP2,BMP7,BNIP3,BNIP3L,BRIP1,CA9,CAPN2,CARD16,CASP1,CASP3,CASR,CAT,CAV1,CBL,CCL2,CCNA2,CCNB1,CD24,CD38,CDK4,CDKN1A,CDKN1B,CFLAR,CHRNB2,CITED2,CLCA1,CLDN3,COL1A1,COX4I2,CPEB1,CPEB2,CPEB4,CREB1,CRYAB,CTGF,CUL2,CXCR4,CYB5R4,CYBA,CYBB,CYGB,CYP1A1,DDIT4,DNM1L,DNMT3A,DNMT3B,DRD2,E2F1,EDN1,EEF2K,EGLN1,EGLN2,EGLN3,EGR1,EIF4EBP1,ELOB,ELOC,ENDOG,EP300,EPAS1,EPO,ERCC2,ERCC3,ERO1A,ETS1,F7,FABP1,FAM162A,FAS,FIS1,FMN2,FOXO1,FUNDC1,GATA6,GNGT1,HDAC2,HIF1A,HIF1AN,HIF3A,HIGD1A,HIPK2,HMOX1,HMOX2,HSD11B2,HSF1,HSP90B1,HYOU1,IRAK1,ITGA2,ITPR1,ITPR2,KCNA5,KCND2,KCNK2,KCNK3,KCNMA1,KCNMB1,LDHA,LEP,LIMD1,LMNA,LONP1,LOXL2,LPAR1,MB,MDM2,MDM4,MECP2,MGARP,MMP14,MTHFR,MTOR,MYB,MYC,MYOCD,MYOD1,NARFL,NDNF,NDRG1,NF1,NKX3-1,NOL3,NOP53,NOS1,NOS2,NOTCH1,NOX4,NPEPPS,NPPC,NR4A2,OPA1,OPRD1,OXTR,P2RX2,P2RX3,P4HB,PAK1,PAM,PCK1,PDGFRB,PDK3,PDLIM1,PENK,PGK1,PICK1,PINK1,PKLR,PKM,PLAT,PLAU,PLK3,PLOD2,PMAIP1,PML,POLB,PPARA,PPARD,PPARG,PPARGC1A,PRKAA1,PRKCB,PRKCE,PSEN2,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTEN,PTGIS,PTK2B,PTN,RAF1,RAMP2,RBPJ,RGCC,RPS27A,RYR1,RYR2,S100B,SCFD1,SFRP1,SIRT1,SIRT2,SIRT4,SLC29A1,SLC2A8,SLC6A4,SLC8A1,SLC8A3,SLC9A1,SMAD4,SOD3,SRC,SRF,STC1,STC2,SUV39H2,TBL2,TEK,TERT,TGFB1,TGFB2,TGFBR2,TH,THBS1,TIGAR,TLR2,TM9SF4,TMEM199,TP53,TRPC6,TWIST1,TXN2,UBC,UBE2D1,UBE2D2,UBE2D3,UBQLN1,UCN3,UCP2,UCP3,USF1,UTS2,VCAM1,VEGFA,VEGFB,VEGFC,VEGFD,XRCC1,ZFP36L1,ZNF354A	TetrapodAncestor	86.1854
GO.Biological.Process	GO:0051972	regulation.of.telomerase.activity	425	5.827131e-91	7.526905e-87	1.771036e-89	1.496666e+0	ACD,AURKB,CCT2,CCT4,CERS1,CTNNB1,DKC1,GREM1,GRHL2,HMBOX1,HNRNPA2B1,HNRNPD,HSP90AB1,KLF4,MAP2K7,MAP3K4,MAPK1,MAPK15,MAPK3,MAPKAPK5,MEN1,MYC,NAF1,NEK7,NVL,PARM1,PARN,PARP4,PIF1,PINX1,PKIB,PNKP,POT1,PPARG,PRKCQ,SMG6,SRC,TCP1,TERF1,TNKS,TP53,WRAP53,XRCC5	TetrapodAncestor	86.1234
GO.Biological.Process	GO:0061383	trabecula.morphogenesis	426	1.055783e-90	1.363755e-86	3.201303e-89	1.499536e+0	ADAMTS1,ADGRG6,BMP10,BMP5,BMP7,BMPR1A,CAV3,CCM2L,CHD7,COL1A1,DLL4,EGLN1,ENG,FBN2,FHL2,FKBP1A,FOXH1,HEG1,HEY1,HEY2,MSX2,NKX2-5,NOG,NOTCH1,NRG1,OVOL2,PLXNB1,PPARGC1B,RBP4,RBPJ,S1PR1,SEMA4D,SFRP1,SLC40A1,SOS1,SRF,TEK,TGFB2,TGFBR1,THBS3,WNT10B	TetrapodAncestor	85.8653
GO.Biological.Process	GO:0046328	regulation.of.JNK.cascade	427	4.407415e-90	5.693058e-86	1.333269e-88	1.252132e+0	AGER,AIDA,AMBP,ANKRD6,APP,CCL19,CCL21,CCR7,CD27,CDC42,CTGF,DAB2IP,DACT1,DAXX,DBNL,DKK1,DNAJA1,DTNBP1,DUSP10,DUSP15,DUSP19,DUSP22,DUSP3,DVL3,EDA2R,EDAR,EDN1,EGFR,EPHA4,EPHB1,ERCC6,ERN1,ERN2,F2RL1,FGD2,FGF19,FKTN,FLT4,FZD10,FZD4,FZD5,FZD7,FZD8,GADD45A,GADD45B,GADD45G,GRIK2,GSTP1,HACD3,HDAC3,HIPK2,HMGB1,HRAS,IGF1R,IL1B,ITCH,LTBR,MAGI3,MAP2K4,MAP2K7,MAP3K10,MAP3K11,MAP3K2,MAP3K21,MAP3K4,MAP3K5,MAP3K6,MAP3K7,MAP3K9,MAP4K1,MAP4K4,MAPK8IP1,MAPK8IP3,MARVELD3,MECOM,MEN1,MINK1,MUL1,NCF1,NOD1,NRK,PAFAH1B1,PAK1,PER1,PHLPP1,PINK1,PKN1,PLCB1,PPEF2,PRKN,PTK2B,PTPN1,PTPN22,PYCARD,RAP2A,RAPGEF1,RASGRP1,RASSF2,RB1CC1,RIPK1,RIPK2,ROR2,RPS3,SASH1,SDCBP,SERPINB3,SFRP1,SFRP2,SH3RF1,SPAG9,SYK,TAOK1,TAOK2,TIAM1,TIRAP,TLR3,TLR4,TLR6,TLR9,TNF,TNFRSF11A,TNFRSF19,TNFSF11,TNIK,TP73,TPD52L1,TRAF2,TRAF4,TRAF6,ULK4,UNC5CL,VANGL2,WNT16,WNT5A,WNT7A,WNT7B,ZNF622,ZNF675	TetrapodAncestor	85.2447
GO.Biological.Process	GO:0045089	positive.regulation.of.innate.immune.response	428	1.202096e-89	1.552747e-85	3.627914e-88	1.248810e+0	ADAM8,AP1G1,APOB,BCL10,BIRC2,BIRC3,BTK,BTRC,CADM1,CARD11,CASP8,CCL5,CD14,CD180,CD1D,CD209,CD226,CD300LF,CD36,CD86,CHUK,CLEC4A,CLEC4C,CLEC4D,CLEC4E,CLEC6A,CLEC7A,CNPY3,COLEC12,CRTAM,CTSB,CTSL,CUL1,DDX58,DHX9,DMBT1,ENSG00000173366,EP300,EREG,FADD,FBXW11,FCER1G,FCN1,FFAR2,FGG,HAVCR2,HCK,HEXIM1,HMGB1,HMGB2,HRAS,HSP90B1,ICAM2,IFNB1,IFNK,IKBKB,IKBKE,IKBKG,IL12A,IL12B,IL18RAP,IL21,INAVA,IRAK1,IRAK3,IRAK4,IRF3,IRF7,IRGM,ITCH,ITGAM,ITGB2,KLRK1,KRAS,LBP,LGMN,LRRC70,LY96,LYN,MALT1,MAP2K6,MAP3K1,MAP3K7,MAPKAPK2,MAPKAPK3,MARCO,MATR3,MB21D1,MMP12,MUC1,MUC12,MUC13,MUC15,MUC20,MUC3A,MUC4,MUC5AC,MUC5B,MUC6,MUCL1,NCR3,NECTIN2,NFKB1,NLRC4,NLRC5,NOD1,NR1H4,NRAS,OTULIN,PAK1,PAK2,PAK3,PARP9,PDPK1,PGLYRP1,PGLYRP2,PGLYRP3,PGLYRP4,PIK3AP1,PIK3C3,PLCG2,PLSCR1,POLR3B,POLR3C,POLR3D,POLR3F,PQBP1,PRKACA,PRKACG,PRKCD,PRKCE,PRKDC,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PSPC1,PYCARD,RAF1,RASGRP1,RBM14,REG3G,RELA,RELB,RFTN1,RIOK3,RIPK1,RIPK2,RPS27A,RPS6KA3,RPS6KA5,S100A1,S100A14,S100A8,S100A9,SFPQ,SH2D1A,SH2D1B,SLAMF6,SNAI3,SRC,SYK,TAB1,TAB2,TAB3,TBK1,TICAM1,TICAM2,TIRAP,TLR1,TLR10,TLR2,TLR3,TLR4,TLR5,TLR6,TLR9,TMEM173,TMEM189-UBE2V1,TNFAIP3,TNIP1,TNIP2,TNIP3,TRAF3,TRAF6,TRIL,TRIM5,TRIM6,TXK,UBC,UBE2D1,UBE2D2,UBE2D3,UBE2N,UNC93B1,VAV1,WNT5A,XRCC5,XRCC6	TetrapodAncestor	84.8089
GO.Biological.Process	GO:0043122	regulation.of.I-kappaB.kinase/NF-kappaB.signaling	429	2.254539e-89	2.912188e-85	6.788317e-88	1.252471e+0	ABL1,ADIPOQ,AGER,AJUBA,AKAP13,ANGPT1,ANKRD17,APOL3,APP,ASH1L,BCL10,BCL3,BIRC2,BIRC3,BMP7,BRD4,BST2,BTRC,C18orf32,C1QTNF3,C8orf4,CANT1,CARD11,CARD16,CARD19,CASP1,CASP10,CASP8,CC2D1A,CCDC22,CCL19,CCL21,CCR7,CD27,CD36,CD40,CD74,CFLAR,CHUK,CLEC6A,CTH,CTNNB1,CXXC5,DAB2IP,DDRGK1,ECT2,EDA,EDA2R,EDAR,EEF1D,ESR1,F2R,F2RL1,FADD,FAF1,FASLG,FBXW11,FKBP1A,FLNA,G3BP2,GJA1,GOLT1B,GPRC5B,GREM1,GSTP1,HMOX1,HSPB1,HTR2B,IFIT5,IKBKB,IKBKE,IKBKG,IL10,IL12B,IL18,IL18R1,IL1B,IL1RL1,IL23A,INAVA,IRAK1,IRAK4,IRF3,LGALS1,LGALS9,LITAF,LPAR1,LTBR,LURAP1,MALT1,MAP3K14,MAP3K3,MAP3K7,MIB2,MID2,MIER1,MTDH,MUL1,NDFIP1,NDFIP2,NEK6,NFKBID,NLRC3,NLRP6,NLRX1,NOD1,NOL3,NOV,NR1H4,NUP62,OPTN,OTUD7A,OTUD7B,PDPK1,PELI1,PELI2,PER1,PIM2,PINK1,PLEKHG5,PLK2,PPP5C,PRDX1,PRKCB,PRKCE,PRKD1,PRKN,PSMD10,PYCARD,PYDC2,RBCK1,REL,RELA,RHOC,RIOK3,RIPK1,RIPK2,RNF31,RPS27A,S100A12,S100A13,S100A4,S100B,SECTM1,SHARPIN,SIRT1,SLC44A2,SPHK1,SQSTM1,STAT1,TAB2,TBK1,TERF2IP,TFG,TGM2,TICAM1,TICAM2,TIRAP,TLE1,TLR2,TLR3,TLR4,TLR6,TLR9,TMED4,TMEM101,TMEM189-UBE2V1,TNF,TNFAIP3,TNFRSF10B,TNFRSF19,TNFRSF1A,TNFSF10,TNFSF11,TNFSF14,TNIP1,TNIP2,TNIP3,TRADD,TRAF2,TRAF5,TRAF6,TRIM13,TRIM22,TRIM25,TRIM32,TRIM38,TRIM5,TRIM62,TRIM8,TRIP6,TSPAN6,UBC,UBE2I,UBE2N,UNC5CL,USP10,VAPA,WLS,ZC3H12A,ZDHHC13,ZDHHC17,ZFAND6	TetrapodAncestor	84.5358
GO.Biological.Process	GO:0002053	positive.regulation.of.mesenchymal.cell.proliferation	430	2.273120e-89	2.936189e-85	6.828347e-88	1.458130e+0	BMPR1A,CHRD,CTNNB1,FGF9,FGFR1,FGFR2,FOXF1,FOXP2,IHH,IRS2,LRP5,MYC,MYCN,PDGFA,PRRX1,SHOX2,SMO,SOX9,STAT1,TBX1,TGFBR2,TP63,VEGFA,WNT5A	TetrapodAncestor	84.5322
GO.Biological.Process	GO:0036230	granulocyte.activation	431	3.238458e-89	4.183116e-85	9.705606e-88	1.206694e+0	A1BG,ABCA13,ACPP,ACTR10,ACTR2,ADA2,ADAM8,ADGRE3,ADGRE5,ADGRG3,AGA,AGL,AGPAT2,AHSG,ALAD,ALDH3B1,ALDOA,ALOX5,ANO6,ANPEP,ANXA3,AOC1,AP1M1,AP2A2,APAF1,APEH,ARG1,ARL8A,ARPC5,ASAH1,ATAD3B,ATP11A,ATP11B,ATP6AP2,ATP6V0C,ATP6V1D,ATP8A1,ATP8B4,B4GALT1,BPI,BST1,BST2,C16orf62,C1orf35,C3,C3AR1,C6orf120,CAB39,CALML5,CAND1,CANT1,CAP1,CAPN1,CAT,CCL3,CCL5,CCT2,CCT8,CD14,CD300A,CD33,CD36,CD44,CD47,CD53,CD55,CD58,CD59,CD63,CD68,CD93,CDA,CDK13,CFP,CHI3L1,CHIT1,CHRNB4,CKAP4,CLEC12A,CLEC4C,CLEC4D,CMTM6,COMMD3,COMMD9,COTL1,CPNE3,CPPED1,CR1,CRACR2A,CREG1,CRISP3,CRISPLD2,CSNK2B,CSTB,CTSA,CTSB,CTSC,CTSD,CTSH,CTSZ,CXCL1,CXCL6,CXCL8,CXCR1,CXCR2,CYB5R3,CYBA,CYBB,CYFIP1,CYSTM1,DBNL,DDOST,DDX3X,DEGS1,DERA,DGAT1,DIAPH1,DNAJC13,DNASE1L1,DOCK2,DOK3,DPP7,DSC1,DSG1,DSN1,DSP,DYNC1H1,DYNC1LI1,DYNLL1,DYNLT1,EEF1A1,EEF2,ENPP4,EPX,F2RL1,FABP5,FAF2,FCAR,FCER1G,FCN1,FGL2,FGR,FLG2,FRK,FRMPD3,FTH1,FTL,FUCA1,FUCA2,GAA,GDI2,GGH,GLA,GLB1,GLIPR1,GM2A,GMFG,GNS,GOLGA7,GPR84,GRN,GSDMD,GSN,GSTP1,GUSB,GYG1,HBB,HEBP2,HK3,HMGB1,HMOX2,HP,HPSE,HRNR,HSP90AB1,HSPA8,IGF2R,IL18,IL18RAP,ILF2,IMPDH1,IQGAP1,IST1,ITGAM,ITGAV,ITGAX,ITGB2,JUP,KARS,KCNAB2,KMT2E,KPNB1,KRT1,LAIR1,LAMTOR2,LAMTOR3,LCN2,LGALS3,LILRB2,LRG1,LRMP,LRRC7,LYZ,MAN2B1,MANBA,MAPK1,MAPK14,MCEMP1,MGAM,MGST1,MIF,MLEC,MME,MMP25,MMP8,MMP9,MOSPD2,MPO,MS4A3,MVP,NAPRT,NBEAL2,NCKAP1L,NCSTN,NDUFC2,NFAM1,NFASC,NFKB1,NHLRC3,NIT2,NME2,NPC2,NRAS,OLFM4,OLR1,ORM1,ORM2,ORMDL3,OSCAR,OSTF1,PADI2,PAFAH1B2,PDAP1,PDXK,PECAM1,PFKL,PGAM1,PGLYRP1,PGM2,PGRMC1,PIGR,PKM,PKP1,PLAC8,PLAU,PLD1,PLEKHO2,PNP,PPBP,PPIE,PRCP,PRDX4,PREX1,PRG2,PRG3,PRKCD,PRSS2,PRSS3,PSAP,PSEN1,PSMA2,PSMB1,PSMB7,PSMC2,PSMC3,PSMD1,PSMD11,PSMD13,PSMD2,PSMD3,PSMD7,PTAFR,PTGES2,PTPRB,PTPRJ,PTPRN2,PTX3,PYCARD,PYGB,QPCT,QSOX1,RAB14,RAB18,RAB24,RAB27A,RAB31,RAB37,RAB3D,RAB44,RAB4B,RAB5B,RAB6A,RAB7A,RAB9B,RAC1,RAP1A,RAP1B,RAP2B,RAP2C,RETN,RHOG,RNASET2,S100A11,S100A12,S100A7,S100A8,S100A9,S100P,SDCBP,SELL,SERPINA1,SERPINA3,SERPINB1,SERPINB10,SERPINB12,SERPINB3,SERPINB6,SIGLEC9,SIRPA,SIRPB1,SLC11A1,SLC15A4,SLC27A2,SLC2A3,SLC44A2,SLCO4C1,SLPI,SNAP23,SNAP25,SNAP29,SRP14,STBD1,STK11IP,STOM,STXBP2,SURF4,SVIP,SYK,SYNGR1,TARM1,TBC1D10C,TCIRG1,TCN1,TICAM2,TIMP2,TLR2,TMBIM1,TMC6,TMEM173,TMEM63A,TNFAIP6,TNFRSF1B,TOLLIP,TOM1,TRAPPC1,TRPM2,TTR,TUBB,TUBB4B,TXNDC5,UBR4,VAMP2,VAMP8,VAPA,VAT1,VCL,VCP,VNN1,XRCC5,XRCC6,YPEL5	TetrapodAncestor	84.3785
GO.Biological.Process	GO:0007411	axon.guidance	432	3.321006e-89	4.289743e-85	9.929962e-88	1.172278e+0	ALCAM,ANOS1,APBB2,APP,ARHGAP35,ARTN,ARX,ATOH1,B3GNT2,BCL11B,BDNF,BMP7,BMPR1B,BOC,CDH4,CDK5,CDK5R1,CHL1,CNTN2,CNTN4,CREB1,CRMP1,CSF1R,CXCR4,DAB1,DCC,DLX5,DOK1,DOK2,DOK4,DOK5,DOK6,DPYSL2,DPYSL5,DRAXIN,DVL1,EFNA1,EFNA3,EFNA4,EFNA5,EFNB1,EFNB2,EFNB3,EGR2,ENAH,ENSG00000251246,EPHA4,EPHA5,EPHA7,EPHA8,EPHB1,EPHB2,EPHB3,ERBB2,ETV1,EVL,EXT1,EZR,FAM129B,FEZ1,FEZ2,FEZF1,FLRT2,FLRT3,FOXG1,FRS2,FZD3,GAB1,GAB2,GAP43,GATA3,GBX1,GBX2,GDNF,GFRA1,GFRA2,GFRA3,GFRA4,GLI2,GLI3,GPC1,GRB10,GRB2,GRB7,HRAS,IRS2,ISL1,ISPD,KIF5A,KIF5B,KIF5C,KIRREL1,KLF7,KRAS,L1CAM,LAMA2,LHX1,LHX2,LHX4,LMX1A,LYPLA2,MAPK1,MAPK3,MATN2,NCAM1,NECTIN1,NEO1,NFASC,NFIB,NGFR,NOG,NPHS1,NR4A3,NRAS,NRP1,NRP2,NRTN,NRXN1,NRXN3,NTN3,NTRK1,OPHN1,OR10A4,OTX2,PDLIM7,PIK3CA,PIK3CD,PIK3R1,PLA2G10,PLCG1,PLXNA1,PLXNA2,PLXNA3,PLXNA4,POU4F3,PRKCA,PRKCQ,PSPN,PTCH1,PTK2,PTPN11,PTPRA,PTPRM,PTPRO,RANBP9,RAP1GAP,RELN,RET,ROBO1,ROBO2,ROBO3,RPL24,RPS6KA5,RYK,SCN1B,SEMA3A,SEMA3C,SEMA6A,SEMA6C,SH3KBP1,SHC1,SHC3,SIAH1,SIAH2,SLIT1,SLIT2,SLIT3,SMAD4,SOS1,SPON2,SPTB,SPTBN2,SPTBN5,SRC,TNFRSF8,TNR,TUBB3,UNC5A,UNC5B,UNC5C,UNC5D,VANGL2,VASP,VEGFA,VLDLR,WNT3,WNT3A,WNT5A	TetrapodAncestor	84.3676
GO.Biological.Process	GO:0045055	regulated.exocytosis	433	4.116307e-89	5.317034e-85	1.227952e-87	1.159077e+0	A1BG,A2M,ABCA12,ABCA13,ACPP,ACTN1,ACTN4,ACTR10,ACTR2,ADA2,ADAM8,ADGRE3,ADGRE5,ADGRG3,AGA,AGL,AGPAT2,AHSG,ALAD,ALB,ALDH3B1,ALDOA,ALOX5,ANO6,ANPEP,ANXA3,ANXA5,AOC1,AP1M1,AP2A2,APAF1,APEH,APLP2,APOA1,APOH,APOOL,APP,ARG1,ARL8A,ARPC5,ASAH1,ATAD3B,ATP11A,ATP11B,ATP6AP2,ATP6V0C,ATP6V1D,ATP8A1,ATP8B4,B4GALT1,BLOC1S6,BPI,BRPF3,BST1,BST2,BTK,C16orf62,C1orf35,C3,C3AR1,C6orf120,CAB39,CADPS,CADPS2,CALM1,CALML5,CAND1,CANT1,CAP1,CAPN1,CAT,CBL,CCL3,CCT2,CCT8,CD109,CD14,CD300A,CD33,CD36,CD44,CD47,CD53,CD55,CD58,CD59,CD63,CD68,CD9,CD93,CDA,CDC37L1,CDK13,CDK5,CFP,CHGA,CHI3L1,CHID1,CHIT1,CHP1,CHRNB4,CKAP4,CLEC12A,CLEC3B,CLEC4C,CLEC4D,CLU,CMTM6,COMMD3,COMMD9,CORO1A,COTL1,CPLX1,CPLX2,CPLX3,CPNE3,CPPED1,CR1,CRACR2A,CREG1,CRHBP,CRISP3,CRISPLD2,CSNK2B,CSTB,CTSA,CTSB,CTSC,CTSD,CTSH,CTSW,CTSZ,CXCL1,CXCR1,CXCR2,CYB5R1,CYB5R3,CYBA,CYBB,CYFIP1,CYSTM1,DBNL,DDOST,DDX3X,DEGS1,DERA,DGAT1,DIAPH1,DMTN,DNAJC13,DNASE1L1,DOC2A,DOC2B,DOCK2,DOK3,DPP7,DSC1,DSG1,DSN1,DSP,DYNC1H1,DYNC1LI1,DYNLL1,DYNLT1,EEF1A1,EEF2,EGF,ENDOD1,ENPP4,EPX,EQTN,F13A1,F5,F8,FABP5,FAF2,FAM3C,FAM49B,FCAR,FCER1G,FCN1,FERMT3,FGG,FGL2,FGR,FLG2,FLNA,FN1,FRK,FRMPD3,FTH1,FTL,FUCA1,FUCA2,GAA,GAS6,GDI2,GGH,GLA,GLB1,GLIPR1,GM2A,GMFG,GNS,GOLGA7,GPR84,GRN,GSDMD,GSN,GSTP1,GTPBP2,GUSB,GYG1,HABP4,HBB,HCK,HEBP2,HGF,HK3,HMGB1,HMOX2,HP,HPSE,HRG,HRNR,HSP90AB1,HSPA8,IGF1,IGF2,IGF2R,ILF2,IMPDH1,IQGAP1,ISLR,IST1,ITGA2B,ITGAM,ITGAV,ITGAX,ITGB2,ITIH3,ITIH4,JUP,KCNAB2,KLRF2,KNG1,KPNB1,KRT1,LAIR1,LAMTOR2,LAMTOR3,LAT,LAT2,LCN2,LEFTY2,LGALS3,LGALS3BP,LILRB2,LRG1,LRMP,LRRC7,LYN,LYZ,MAGED2,MAN2B1,MANBA,MANF,MAPK1,MAPK14,MCEMP1,MGAM,MGST1,MIF,MILR1,MLEC,MME,MMP25,MMP8,MMP9,MMRN1,MOSPD2,MPO,MS4A3,MVP,NAPRT,NBEAL2,NCKAP1L,NCSTN,NDUFC2,NFAM1,NFASC,NFKB1,NHLRC3,NIT2,NLGN1,NME2,NPC2,NR4A3,NRAS,OLFM4,OLR1,ORM1,ORM2,ORMDL3,OSCAR,OSTF1,OTOF,P2RX7,PADI2,PAFAH1B2,PCDH7,PCLO,PCYOX1L,PDAP1,PDGFA,PDGFB,PDXK,PECAM1,PF4,PFKL,PGAM1,PGLYRP1,PGM2,PGRMC1,PHACTR2,PIGR,PIK3CD,PIK3CG,PIP5K1C,PKM,PKP1,PLA2G3,PLAC8,PLAU,PLD1,PLEK,PLEKHO2,PLG,PNP,PPBP,PPIE,PPP3CB,PRCP,PRDX4,PRG2,PRG3,PRKCD,PROS1,PRSS2,PRSS3,PSAP,PSEN1,PSMA2,PSMB1,PSMB7,PSMC2,PSMC3,PSMD1,PSMD11,PSMD13,PSMD2,PSMD3,PSMD7,PTAFR,PTGES2,PTPRB,PTPRJ,PTPRN2,PTX3,PYCARD,PYGB,QPCT,QSOX1,RAB11B,RAB11FIP1,RAB11FIP2,RAB11FIP5,RAB14,RAB18,RAB24,RAB26,RAB27A,RAB27B,RAB31,RAB37,RAB3D,RAB44,RAB4B,RAB5B,RAB6A,RAB7A,RAB9B,RAC1,RAP1A,RAP1B,RAP2B,RAP2C,RARRES2,RASGRP1,RETN,RHOG,RIMS1,RIMS3,RIMS4,RNASET2,RPH3A,S100A11,S100A12,S100A13,S100A7,S100A8,S100A9,S100P,SCCPDH,SCG3,SCIN,SCRIB,SDCBP,SDF4,SELENOP,SELL,SELP,SEPT5,SERPINA1,SERPINA3,SERPINA4,SERPINB1,SERPINB10,SERPINB12,SERPINB3,SERPINB6,SERPING1,SIGLEC9,SIRPA,SIRPB1,SLC11A1,SLC15A4,SLC27A2,SLC2A3,SLC44A2,SLCO4C1,SLPI,SNAP23,SNAP25,SNAP29,SNAPIN,SNPH,SOD1,SPP2,SRP14,STBD1,STEAP2,STK11IP,STOM,STX11,STX19,STX1A,STX1B,STX3,STX4,STXBP1,STXBP2,SURF4,SVIP,SYK,SYNGR1,SYNGR2,SYNGR3,SYNJ1,SYT1,SYT10,SYT11,SYT13,SYT15,SYT17,SYT2,SYT4,SYT5,SYT6,SYT7,SYT8,SYT9,SYTL1,SYTL3,SYTL4,SYTL5,TAGLN2,TARM1,TBC1D10C,TCIRG1,TCN1,TEX264,TF,TGFB1,TGFB2,THBS1,TICAM2,TIMP1,TIMP2,TIMP3,TLN1,TLR2,TMBIM1,TMC6,TMED10,TMEM173,TMEM63A,TMEM79,TMX3,TNFAIP6,TNFRSF1B,TOLLIP,TOM1,TRAPPC1,TRIM9,TRPM2,TTN,TTR,TUBB,TUBB4B,TXNDC5,UBR4,UNC13A,UNC13B,UNC13C,VAMP2,VAMP3,VAMP8,VAPA,VAT1,VCL,VCP,VEGFA,VEGFB,VEGFC,VEGFD,VNN1,VPS41,VTI1B,VWF,WDR1,XRCC5,XRCC6,YPEL5,ZP4	TetrapodAncestor	84.2743
GO.Biological.Process	GO:0050821	protein.stabilization	434	5.884524e-89	7.601040e-85	1.751392e-87	1.340101e+0	A1CF,AAK1,ANK2,APOA1,ATP1B1,ATP1B2,ATP1B3,BAG6,CALR,CCNH,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,CDC37L1,CDK7,CDKN1A,CHEK2,CHP1,CLU,COG3,COG7,CPN2,CREB1,CREBL2,CRTAP,CRYAA,CRYAB,DSG1,DVL1,DVL3,EFNA1,EP300,EPHA4,FBXW7,FLNA,FLOT1,FLOT2,GAPDH,GNAQ,GOLGA7,GPIHBP1,GTSE1,HCFC1,HIP1,HIP1R,HPS4,HSP90AB1,HYPK,IFT46,IGF1,IRGM,MDM4,MSX1,MUL1,NAA15,NAA16,NAPG,NLK,NOP53,NPM1,OTUD3,P3H1,PARK7,PDCD10,PER3,PEX19,PEX6,PFN1,PFN2,PHB,PIK3R1,PIM2,PIN1,PINK1,PLPP3,PPARGC1A,PPIB,PRKCD,PRKN,PRKRA,PTEN,RASSF2,RPL11,RPL23,RPL5,RPS7,RTN4,SAXO1,SEL1L,SERPINA6,SMAD7,SMO,SOX17,SOX4,STK4,STX12,STXBP1,STXBP4,SUMO1,SWSAP1,SYVN1,TAF1,TAF9,TAF9B,TBRG1,TCP1,TELO2,TESC,TNIP2,TRIM44,USP13,USP2,USP7,WDR81,WFS1,WIZ,WNT10B,ZBED3,ZNF207	TetrapodAncestor	84.1191
GO.Biological.Process	GO:0032526	response.to.retinoic.acid	435	6.517489e-89	8.418641e-85	1.935320e-87	1.322686e+0	ABCA1,ABL2,ACER2,ADNP2,AQP1,AQP3,ASCL1,ASXL1,BMP6,BRINP1,BRINP2,BRINP3,CCL2,CD38,CDKN2D,CLK2,COL1A1,CTSH,CYP26B1,DKK1,DUSP1,EPHA3,FGFR2,FZD10,FZD4,FZD7,GDAP1,GJA1,GJB3,HDAC2,HSD17B2,HTRA2,IGF2R,IGFBP2,IGFBP7,KLF4,KRT13,LEP,LTK,LYN,MYB,MYOG,NCOA1,NTRK3,OSR1,OVCA2,OXT,PAX2,PCK1,PDGFRB,PPARG,PTCH1,PTGES,PTK2B,PTK7,RARA,RARG,RBP4,RET,RORB,RXRA,SETX,SLC10A3,SLC6A4,SNRNP70,SNW1,SOX9,SREBF1,STRA8,T,TBX1,TEAD2,TESC,TIE1,TMEM161A,TNC,TRIML2,TWF2,WNT10B,WNT11,WNT3,WNT3A,WNT5A,WNT6,WNT7B,WNT8A,WNT8B,WNT9A,WNT9B,YES1	TetrapodAncestor	84.0748
GO.Biological.Process	GO:0010817	regulation.of.hormone.levels	436	7.457528e-89	9.632889e-85	2.209378e-87	1.151311e+0	AACS,AANAT,ABAT,ABCB4,ABCC2,ABCC8,ACE,ACE2,ACVR2B,ADCY5,ADCYAP1,ADH4,ADH7,ADIPOQ,ADORA1,ADRA2A,ADRA2B,ADRA2C,AFP,AGT,AGTR1,AGTR2,AKR1B1,AKR1B15,AKR1D1,ALDH1A1,ALDH1A3,ALDH8A1,ALDH9A1,ANO1,ANXA1,APLN,AQP1,ARHGEF7,ARL2,ARL2BP,ARNTL,ARRB1,ASMT,ATP1A1,ATP6AP2,AWAT2,BACE2,BAD,BCAT2,BCO1,BCO2,BLK,BMP2,BMP5,BMP6,BMP8A,BRSK2,BTK,C1QTNF1,C1QTNF12,C1QTNF3,C2CD2L,C9orf3,CACNA1A,CACNA1C,CACNA1D,CACNA1E,CACNA1H,CACNA2D2,CAMK2G,CAPN10,CARTPT,CASR,CCKAR,CCL5,CD38,CDK16,CFTR,CGA,CGB3,CGB5,CGB8,CHD7,CHST8,CHST9,CNR1,CORIN,CPA3,CPLX1,CPLX3,CPN1,CPQ,CPT1A,CRABP1,CRABP2,CREB1,CRHBP,CRHR1,CRY1,CRYM,CTSZ,CYB5R4,CYP11A1,CYP11B1,CYP11B2,CYP17A1,CYP19A1,CYP1A1,CYP1B1,CYP26A1,CYP26B1,CYP26C1,CYP27C1,DDO,DGAT1,DGAT2,DGKQ,DHCR7,DHRS11,DHRS2,DHRS3,DHRS4,DIO1,DIO2,DIO3,DKK3,DOC2B,DRD2,DUOX1,DUOX2,DUOXA1,DUOXA2,ECE2,EDN1,EDN3,EFNA5,EGFR,EGR1,EIF2AK3,ENPEP,EPHA5,ERO1B,ESR1,EXOC3L1,FAM129B,FAM3B,FAM3D,FDX1,FDXR,FFAR1,FFAR2,FFAR3,FFAR4,FGF23,FGFR1,FGG,FKBP1B,FOXA1,FOXA2,FOXE1,FSHB,FURIN,FZD4,GAL,GATA3,GCK,GCNT4,GHRH,GHRHR,GHSR,GIP,GIPR,GJA1,GLP1R,GLUD1,GLUL,GNAS,GPER1,GPLD1,GPR119,GPR68,GRP,HIF1A,HMGCR,HMGN3,HNF1B,HNF4A,HPN,HSD17B1,HSD17B11,HSD17B12,HSD17B14,HSD17B2,HSD17B3,HSD17B4,HSD17B6,HSD17B7,HSD17B8,HSD3B1,HSD3B2,HTR1A,HTR2A,HTR2C,ICA1,IDE,IFNG,IL1B,IL1RN,IL6,ILDR2,INHA,INHBA,INHBB,INS,IRS1,IRS2,ISL1,ITPR1,ITPR2,ITPR3,IYD,JAGN1,JAK2,KALRN,KCNA5,KCNB1,KCNC2,KCNG2,KCNJ11,KCNS3,KIF5B,KISS1,LEP,LHB,LIF,LRAT,LRP5,LTBP4,LYN,MAFA,MAP4K4,MARCKS,MC4R,MCU,MME,MPC2,MTNR1B,MYRIP,NDUFAF2,NEUROD1,NGF,NKX3-1,NKX6-1,NNAT,NOS2,NOV,NPFF,NPVF,NR0B2,NR1D1,NR1H4,NRXN1,OPRK1,OSM,OXCT1,P2RY1,PARK7,PASK,PAX8,PCK2,PCLO,PCSK1,PCSK1N,PCSK2,PCSK5,PCSK6,PCSK7,PDE8B,PER2,PFKFB2,PFKL,PHPT1,PIM3,PLA2G6,PLB1,PLEKHA1,PNPLA4,POMC,POR,PPARD,PPARGC1A,PPP3CA,PPP3CB,PRKCA,PRKCE,PRKN,PRLHR,PSMD9,PTPN11,PTPRN2,RAB11B,RAB11FIP1,RAB11FIP2,RAB11FIP5,RAB1A,RAB8B,RAF1,RAP1A,RAPGEF3,RASL10B,RBP1,RBP4,RDH10,RDH13,RDH14,RDH5,RDH8,REN,REST,RETN,RETSAT,RFX3,RFX6,RPE65,SAFB,SCARB1,SCG5,SCPEP1,SCT,SDR16C5,SELENOM,SELENOT,SERP1,SERPINA7,SFRP1,SGPL1,SIDT2,SIRT3,SIRT4,SLC16A1,SLC16A2,SLC22A1,SLC22A9,SLC25A5,SLC25A6,SLC2A1,SLC2A2,SLC30A8,SLC5A5,SLC8B1,SLC9B2,SLCO1B1,SLCO1C1,SLCO4A1,SMAD2,SMAD4,SMPD3,SNAP23,SNAP25,SNX19,SNX4,SOX11,SOX4,SOX8,SPP1,SRD5A1,SRD5A2,SREBF1,SRI,SSTR5,STAR,STARD3NL,STC2,STUB1,STX1A,STX4,STXBP4,STXBP5L,SULT1A1,SYBU,SYT7,SYT9,SYTL4,TAC1,TARDBP,TBX3,TFAP2B,TFR2,TG,TIAM1,TIPARP,TM7SF3,TMEM27,TNF,TNFSF11,TPO,TRERF1,TRPM4,TSHB,TSPO,TSPOAP1,TTR,UBE2Q1,UCN,UCN3,UCP2,UGT1A1,UGT1A3,UGT1A8,UGT1A9,UQCC2,UTS2,VAMP8,VIP,VSNL1,WNT4	TetrapodAncestor	84.0162
GO.Biological.Process	GO:0001889	liver.development	437	7.873362e-89	1.017002e-84	2.327236e-87	1.300724e+0	AACS,ACAT1,ADA,ANXA1,ARF6,ARG1,ARID5B,ASNS,AURKA,BAAT,CCDC40,CCND1,CEBPA,CEBPB,CEBPG,CITED2,CLDN1,COBL,CPB2,CPS1,CSNK2A1,CSNK2A2,CSNK2B,CUL3,CYP1A1,DBP,DNAAF1,E2F7,E2F8,EGFR,EPHX1,EZH2,FPGS,GATA6,GFER,GLI3,GNPNAT1,HAMP,HES1,HGF,HHEX,HLX,HMGCL,HMGCS1,HMOX1,HNF1B,HNRNPD,IGF2R,IHH,IL10,ITGA2,JARID2,JUN,KRAS,LSR,MAN2A1,MPST,NF1,NOTCH1,NPHP3,ONECUT1,OTC,PCNA,PHF2,PIK3CA,PKD1,PKD2,PKM,PNPT1,PRMT5,PROC,PROX1,PTCD2,PTCH1,PTN,PTPN3,QDPR,RAP1A,RARA,RB1CC1,RELA,RGN,RHBDD3,RPS16,RPS6KA1,SEC63,SOX9,SRD5A1,SRSF1,SRSF5,SULF2,TGFB1,TYMS,UCP2,UGT1A1,UPF2,VTN,WDR35,WNT1,WNT4,XBP1,ZIC3	TetrapodAncestor	83.9927
GO.Biological.Process	GO:0031057	negative.regulation.of.histone.modification	438	8.463765e-89	1.093265e-84	2.496038e-87	1.652918e+0	ATG5,BCOR,BRCA1,CTBP1,DNMT3B,FOXP3,H2AFY,HDAC8,JARID2,KDM3A,KDM4C,KDM5A,MECP2,MTF2,NOC2L,OTUB1,PAX5,PHF1,PIH1D1,SDR16C5,SIRT1,SKI,SMARCB1,SNCA,SPI1,TRIP12,TWIST1,UBR5,UCN	TetrapodAncestor	83.9613
GO.Biological.Process	GO:0042119	neutrophil.activation	439	1.065080e-88	1.375764e-84	3.133858e-87	1.206143e+0	A1BG,ABCA13,ACPP,ACTR10,ACTR2,ADA2,ADAM8,ADGRE3,ADGRE5,ADGRG3,AGA,AGL,AGPAT2,AHSG,ALAD,ALDH3B1,ALDOA,ALOX5,ANO6,ANPEP,ANXA3,AOC1,AP1M1,AP2A2,APAF1,APEH,ARG1,ARL8A,ARPC5,ASAH1,ATAD3B,ATP11A,ATP11B,ATP6AP2,ATP6V0C,ATP6V1D,ATP8A1,ATP8B4,B4GALT1,BPI,BST1,BST2,C16orf62,C1orf35,C3,C3AR1,C6orf120,CAB39,CALML5,CAND1,CANT1,CAP1,CAPN1,CAT,CCL5,CCT2,CCT8,CD14,CD300A,CD33,CD36,CD44,CD47,CD53,CD55,CD58,CD59,CD63,CD68,CD93,CDA,CDK13,CFP,CHI3L1,CHIT1,CHRNB4,CKAP4,CLEC12A,CLEC4C,CLEC4D,CMTM6,COMMD3,COMMD9,COTL1,CPNE3,CPPED1,CR1,CRACR2A,CREG1,CRISP3,CRISPLD2,CSNK2B,CSTB,CTSA,CTSB,CTSC,CTSD,CTSH,CTSZ,CXCL1,CXCL6,CXCL8,CXCR1,CXCR2,CYB5R3,CYBA,CYBB,CYFIP1,CYSTM1,DBNL,DDOST,DDX3X,DEGS1,DERA,DGAT1,DIAPH1,DNAJC13,DNASE1L1,DOCK2,DOK3,DPP7,DSC1,DSG1,DSN1,DSP,DYNC1H1,DYNC1LI1,DYNLL1,DYNLT1,EEF1A1,EEF2,ENPP4,EPX,F2RL1,FABP5,FAF2,FCAR,FCER1G,FCN1,FGL2,FGR,FLG2,FRK,FRMPD3,FTH1,FTL,FUCA1,FUCA2,GAA,GDI2,GGH,GLA,GLB1,GLIPR1,GM2A,GMFG,GNS,GOLGA7,GPR84,GRN,GSDMD,GSN,GSTP1,GUSB,GYG1,HBB,HEBP2,HK3,HMGB1,HMOX2,HP,HPSE,HRNR,HSP90AB1,HSPA8,IGF2R,IL18,IL18RAP,ILF2,IMPDH1,IQGAP1,IST1,ITGAM,ITGAV,ITGAX,ITGB2,JUP,KCNAB2,KMT2E,KPNB1,KRT1,LAIR1,LAMTOR2,LAMTOR3,LCN2,LGALS3,LILRB2,LRG1,LRMP,LRRC7,LYZ,MAN2B1,MANBA,MAPK1,MAPK14,MCEMP1,MGAM,MGST1,MIF,MLEC,MME,MMP25,MMP8,MMP9,MOSPD2,MPO,MS4A3,MVP,NAPRT,NBEAL2,NCKAP1L,NCSTN,NDUFC2,NFAM1,NFASC,NFKB1,NHLRC3,NIT2,NME2,NPC2,NRAS,OLFM4,OLR1,ORM1,ORM2,ORMDL3,OSCAR,OSTF1,PADI2,PAFAH1B2,PDAP1,PDXK,PECAM1,PFKL,PGAM1,PGLYRP1,PGM2,PGRMC1,PIGR,PKM,PKP1,PLAC8,PLAU,PLD1,PLEKHO2,PNP,PPBP,PPIE,PRCP,PRDX4,PREX1,PRG2,PRG3,PRKCD,PRSS2,PRSS3,PSAP,PSEN1,PSMA2,PSMB1,PSMB7,PSMC2,PSMC3,PSMD1,PSMD11,PSMD13,PSMD2,PSMD3,PSMD7,PTAFR,PTGES2,PTPRB,PTPRJ,PTPRN2,PTX3,PYCARD,PYGB,QPCT,QSOX1,RAB14,RAB18,RAB24,RAB27A,RAB31,RAB37,RAB3D,RAB44,RAB4B,RAB5B,RAB6A,RAB7A,RAB9B,RAC1,RAP1A,RAP1B,RAP2B,RAP2C,RETN,RHOG,RNASET2,S100A11,S100A12,S100A7,S100A8,S100A9,S100P,SDCBP,SELL,SERPINA1,SERPINA3,SERPINB1,SERPINB10,SERPINB12,SERPINB3,SERPINB6,SIGLEC9,SIRPA,SIRPB1,SLC11A1,SLC15A4,SLC27A2,SLC2A3,SLC44A2,SLCO4C1,SLPI,SNAP23,SNAP25,SNAP29,SRP14,STBD1,STK11IP,STOM,STXBP2,SURF4,SVIP,SYK,SYNGR1,TARM1,TBC1D10C,TCIRG1,TCN1,TICAM2,TIMP2,TLR2,TMBIM1,TMC6,TMEM173,TMEM63A,TNFAIP6,TNFRSF1B,TOLLIP,TOM1,TRAPPC1,TRPM2,TTR,TUBB,TUBB4B,TXNDC5,UBR4,VAMP8,VAPA,VAT1,VCL,VCP,VNN1,XRCC5,XRCC6,YPEL5	TetrapodAncestor	83.8615
GO.Biological.Process	GO:0044773	mitotic.DNA.damage.checkpoint	440	1.360970e-88	1.757965e-84	3.995375e-87	1.451485e+0	ATM,AURKA,BAX,BTG2,CARM1,CASP2,CCNB1,CCND1,CDC25C,CDK1,CDK2,CDKN1A,CDKN1B,CENPJ,CHEK2,CNOT1,CNOT10,CNOT11,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT8,CRADD,DONSON,E2F1,E2F4,E2F7,E2F8,EME1,EME2,EP300,FANCI,FBXO31,FOXN3,FOXO4,GADD45A,GIGYF2,GML,GTSE1,HMGA2,HUS1,HUS1B,MDC1,MDM2,MDM4,MRE11,MRNIP,MSH2,MUC1,MUS81,NBN,NEK11,NOP53,NPM1,ORAOV1,PCBP4,PCNA,PIDD1,PLAGL1,PLK2,PLK3,PML,PRKDC,PRMT1,RAD9A,RFWD3,RGCC,RPA2,RPS27A,RPS27L,SFN,SOX4,TFDP2,TNKS1BP1,TOPBP1,TP53,TP63,TP73,TRIAP1,UBC,XPC,ZNF385A,ZNF830	TetrapodAncestor	83.755
GO.Biological.Process	GO:0031571	mitotic.G1.DNA.damage.checkpoint	441	1.726305e-88	2.229868e-84	5.056390e-87	1.526959e+0	ATM,AURKA,BAX,BTG2,CARM1,CASP2,CCNB1,CCND1,CDC25C,CDK1,CDK2,CDKN1A,CDKN1B,CENPJ,CHEK2,CNOT1,CNOT10,CNOT11,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT8,CRADD,E2F1,E2F4,E2F7,E2F8,EP300,FBXO31,GADD45A,GIGYF2,GML,GTSE1,MDM2,MDM4,MUC1,NPM1,PCBP4,PCNA,PIDD1,PLAGL1,PLK2,PLK3,PML,PRKDC,PRMT1,RFWD3,RGCC,RPA2,RPS27A,RPS27L,SFN,SOX4,TFDP2,TNKS1BP1,TP53,TP63,TP73,TRIAP1,UBC,ZNF385A	TetrapodAncestor	83.6517
GO.Biological.Process	GO:0050920	regulation.of.chemotaxis	442	1.842787e-88	2.380328e-84	5.385357e-87	1.254407e+0	ADGRA2,AGER,AIF1,ANGPT2,ANO6,ARTN,BMPR2,BST1,C1QBP,C3AR1,C5,CALR,CAMK1D,CASR,CCL1,CCL19,CCL2,CCL21,CCL3,CCL4,CCL5,CCL7,CCR1,CCR2,CCR4,CCR6,CCR7,CD74,CDH13,CMKLR1,CORO1B,CREB3,CSF1,CXCL1,CXCL10,CXCL11,CXCL13,CXCL14,CXCL2,CXCL3,CXCL5,CXCL6,CXCL8,CXCL9,CXCR4,CYP19A1,DAPK2,DDT,DSCAM,EDN1,EDN2,EDN3,EFNB2,F2RL1,F3,F7,FGF1,FGF10,FGF16,FGF18,FGF2,FGF4,FGFR1,GAS6,GPR18,GPR183,GPSM3,GREM1,GSTP1,HMGB1,HRG,HSPB1,IL12A,IL16,IL23A,IL4,IL6,IL6R,ITGA2,JAM3,KARS,KLRK1,LBP,LGALS9,LPAR1,LYN,MAPK14,MAPK3,MEGF8,MET,MIF,MMP28,MOSPD2,MPP1,NBL1,NCKAP1L,NOTCH1,NOV,NRP1,NTF3,NTRK3,P2RX4,PADI2,PDGFB,PDGFD,PDGFRB,PF4,PF4V1,PLA2G7,PLXNA1,PLXNA2,PLXNA3,PLXNA4,PPBP,PPM1F,PRKD1,PRKD2,PTK2B,PTPRO,RAC1,RAC2,RARRES2,RIPOR2,ROBO1,ROBO2,S100A14,S100A7,S1PR1,SCG2,SEMA3A,SEMA5A,SLC8B1,SLIT2,STAP1,STX3,STX4,TGFB1,THBS1,THBS4,TIAM1,TIRAP,TNFSF14,TNFSF18,TUBB2B,USP14,VEGFA,VEGFB,VEGFC,VEGFD,WNT3,WNT3A,WNT5A,XCL1,ZNF580	TetrapodAncestor	83.6234
GO.Biological.Process	GO:0030099	myeloid.cell.differentiation	443	2.428308e-88	3.136645e-84	7.080464e-87	1.274767e+0	ABI1,ACIN1,ACTN1,ADAR,ADD1,APP,ARID4A,ATPIF1,BATF2,BATF3,BCL6,BMP4,CAMK4,CASP3,CASP8,CASP9,CBFB,CCL19,CCR7,CD109,CD86,CDC42,CDKN1C,CDKN2B,CEBPA,CEBPE,CEBPG,CIB1,CLEC1B,CSF1,CSF1R,CSF3,CTNNB1,DHRS2,DMTN,DNASE2,DYRK3,EFNA4,EP300,EPAS1,EPHA2,EPO,ERCC2,F2RL1,FAM20C,FAM210B,FLI1,FLVCR1,G6PD,GAB2,GATA2,GATA3,GLO1,GPC3,GPR183,HBZ,HCLS1,HHEX,HIPK2,HSPA9,IKZF1,IL31RA,IL4,INHA,INHBA,IRF4,IRF8,JAGN1,JAK2,JAK3,JMJD6,JUN,JUNB,KAT6A,KAT8,KLF1,KLF2,KMT2E,L3MBTL3,LEF1,LTBR,LYN,MAEA,MAPK14,MB,MEF2C,MEIS1,MMP9,MYH9,NBEAL2,NCKAP1L,NCOA6,NKX2-3,OCSTAMP,OSTM1,PAFAH1B1,PARP1,PDE1B,PIK3CD,PIP4K2A,PIR,PKNOX1,PML,PPARG,PRDX3,PRKX,PSEN1,PTBP3,PTPN11,RASGRP4,RB1,RBPJ,RELB,RHAG,RPS14,RPS6,SFXN1,SH3PXD2A,SIRT1,SLC25A38,SMAD5,SNRK,SNX10,SPI1,SRC,SRF,TAL1,TESC,TET2,TFRC,TGFB1,TGFBR2,THOC5,THPO,THRA,TIRAP,TLR2,TMOD3,TNF,TNFRSF11A,TNFSF11,TRAF6,TSPAN2,VEGFA,VPS33B,WASF2,WDR1,ZBTB16,ZFPM1,ZNF385A	TetrapodAncestor	83.5035
GO.Biological.Process	GO:0090175	regulation.of.establishment.of.planar.polarity	444	4.065429e-88	5.251315e-84	1.182729e-86	1.369431e+0	ABL1,ANKRD6,AP2A1,AP2A2,AP2B1,AP2M1,AP2S1,ARHGEF19,ARRB2,CDC42,CELSR1,CELSR2,CLTC,DAAM1,DAB2,DACT1,DKK1,DVL1,DVL3,FZD1,FZD2,FZD3,FZD4,FZD5,FZD6,FZD7,GPC3,GPC4,GPC6,GRHL3,MAGI2,MKS1,MLLT3,NPHP3,PARD6A,PFN1,PRICKLE1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTK7,RAC1,ROR2,RPS27A,RSPO3,RYK,SAPCD2,SEC24B,SFRP1,SFRP2,SMURF1,SMURF2,TIAM1,UBC,VANGL1,VANGL2,WNT1,WNT11,WNT5A,WNT9B,ZNRF3	TetrapodAncestor	83.2797
GO.Biological.Process	GO:0030510	regulation.of.BMP.signaling.pathway	445	5.720747e-88	7.389489e-84	1.660559e-86	1.322148e+0	ABL1,ACVR2A,ACVRL1,BMP4,BMPER,BMPR2,CER1,CHRD,CHRDL1,CRB2,CTDSPL2,CYR61,DAND5,DKK1,ENG,FBXL15,FSTL3,FZD1,GATA4,GATA6,GDF2,GDF3,GDF5,GPC3,GREM1,GREM2,HES1,HES5,HFE2,HIPK2,HTRA1,HTRA3,ITGA3,LEMD2,LEMD3,MSX1,MSX2,NBL1,NEO1,NOG,NOTCH1,PCSK6,PELO,RBPJ,RBPMS2,SFRP1,SFRP2,SFRP4,SFRP5,SKI,SKIL,SKOR2,SMAD2,SMAD4,SMAD7,SMURF1,SMURF2,SOST,SOSTDC1,SOX11,TFAP2B,TMPRSS6,TRIM33,VWC2,VWC2L,WNT1,WNT5A,XIAP,ZNF423	TetrapodAncestor	83.1314
GO.Biological.Process	GO:0060416	response.to.growth.hormone	446	5.985278e-88	7.731184e-84	1.733449e-86	1.625759e+0	CACYBP,CPS1,CSH1,F7,GH1,GH2,GHR,GHSR,IGFBP5,JAK2,JAK3,LYN,MAPK1,MAPK3,NME2,PHEX,PIK3R1,PNPT1,PRL,PRLR,PTK2,PTPN1,PXN,RBBP4,SLC34A1,SOCS2,SRD5A1,STAR	TetrapodAncestor	83.1118
GO.Biological.Process	GO:0014066	regulation.of.phosphatidylinositol.3-kinase.signaling	447	1.779304e-87	2.298327e-83	5.141671e-86	1.329319e+0	AGT,ANGPT1,BECN1,C3orf58,CAT,CBL,CCL5,CD28,CRYBA1,CSF3,DAB2IP,DCN,EGFR,ENTPD5,ERBB4,F2,F2R,F2RL1,FBXL2,FGFR1,FGR,FLT1,FSHR,GH1,GPER1,HAX1,HCLS1,HGF,IER3,IGF1,IL18,INS,JAK2,KLF4,LEP,MAPK1,MAPK3,MYDGF,NCF1,NKX3-1,NLRC3,NOP53,NRG1,NTRK2,PDGFA,PDGFB,PDGFC,PDGFD,PDGFRB,PIK3AP1,PIK3IP1,PIP4K2A,PIP4K2B,PIP4K2C,PIP5K1A,PIP5K1B,PIP5K1C,PLXNB1,PPARD,PPP1R16B,PPP2R5B,PPP2R5C,PRR5,PRR5L,PTEN,PTK2,PTPN13,RASGRP1,RELN,RGL2,SELP,SEMA4D,SERPINA12,SERPINE2,SIRT1,SLC9A3R1,SOX9,STAMBP,TEK,TGFB2,TSC2,TWIST1,UBE3A,UNC5B,WNT16	TetrapodAncestor	82.6386
GO.Biological.Process	GO:0043161	proteasome-mediated.ubiquitin-dependent.protein.catabolic.process	448	1.977573e-87	2.554431e-83	5.701855e-86	1.244786e+0	ABTB1,ABTB2,AMER1,AMFR,ANAPC1,ANAPC11,ANAPC16,ANAPC2,ANAPC4,ANAPC5,ANKZF1,APC,ARNTL,ARRB1,ARRB2,ATXN3,AUP1,AURKA,AURKB,BAG6,BFAR,BIRC2,BTBD11,BTBD2,BTBD3,BTBD6,BTBD9,BTRC,C2orf40,CCDC47,CCNB1,CCNF,CD2AP,CDC16,CDC20,CDC23,CDC26,CDC27,CDC34,CDK1,CRBN,CSNK1A1,CTNNB1,CUL1,CUL3,CUL4A,DDB1,DERL1,DERL2,DERL3,DNAJC10,DZIP3,EDEM1,ENSG00000258677,ERCC8,ERLIN1,ERLIN2,FAF1,FAF2,FBXL15,FBXL19,FBXL2,FBXL22,FBXL3,FBXL5,FBXL7,FBXO15,FBXO2,FBXO31,FBXO39,FBXO4,FBXO45,FBXO6,FBXW11,FBXW5,FBXW7,FOXRED2,FZR1,GID4,GSK3A,GTSE1,HECTD3,HECW1,HECW2,HERC2,HSP90B1,HSPA5,ITCH,JKAMP,KAT5,KBTBD4,KCTD13,KCTD17,KCTD2,KCTD5,KIAA0368,KLHL15,KLHL20,KLHL42,MAD2L1,MAEA,MAN1B1,MARCH6,MDM2,MTA1,NEDD4L,NHLRC1,NSFL1C,OS9,PCBP2,PCNP,PLAA,PLK1,PML,POMT1,POMT2,PPP2CB,PPP2R5C,PRKN,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTTG1,RAD23A,RAD23B,RBCK1,RFFL,RFWD2,RLIM,RMND5A,RMND5B,RNF103,RNF11,RNF115,RNF121,RNF122,RNF126,RNF139,RNF145,RNF175,RNF181,RNF185,RNF216,RNF222,RNF24,RNF34,RNF38,RNF4,RNF44,RNF5,RNF6,RNF7,RPS27A,SDF2L1,SEC61B,SEL1L,SGTA,SHARPIN,SIAH1,SIRT1,SIRT2,SKP2,SMURF1,SPOP,SPOPL,STT3B,STUB1,SYVN1,TAF1,TBL1X,TBL1XR1,TMEM129,TMEM67,TMUB1,TNFAIP1,TOPORS,TOR1A,TP53,TRIM13,TRIM25,TRIM72,TRIM9,UBC,UBE2A,UBE2C,UBE2D1,UBE2D3,UBE2E1,UBE2G2,UBE2H,UBE2I,UBE2J1,UBE2J2,UBE2R2,UBE2S,UBE2W,UBE4A,UBQLN1,UBR1,UBR2,UBXN1,UBXN11,UBXN2B,UBXN4,UBXN8,UCHL1,UFD1,UGGT1,VCP,WFS1,WWP1,WWP2,WWTR1,YOD1,ZNRF1,ZNRF2	TetrapodAncestor	82.5927
GO.Biological.Process	GO:0045446	endothelial.cell.differentiation	449	3.580832e-87	4.625361e-83	1.030147e-85	1.374594e+0	ACVR2B,ACVRL1,AFDN,ARHGEF26,BMPR2,CCM2,CLDN1,COL18A1,CTNNB1,DLL1,EDF1,ENG,EZR,F11R,F2RL1,GSTM3,HAPLN2,HEG1,HEY1,HEY2,ID1,JAG1,KDM6B,LAMA5,MARVELD2,MESP1,MET,MSN,MYADM,NOTCH1,NOTCH4,NRG1,NRP1,PDE2A,PDE4D,PDPN,PPP1R16B,PROX1,PTN,PTPRS,RAP1A,RAP1B,RAP2C,RAPGEF1,RAPGEF2,RAPGEF3,RBPJ,RDX,S1PR1,SCUBE1,SMAD4,SOX17,SOX18,STC1,TJP1,TJP2,TMEM100,TNMD,VEZF1,WNT7A,WNT7B	TetrapodAncestor	82.3349
GO.Biological.Process	GO:0070613	regulation.of.protein.processing	450	5.241879e-87	6.770935e-83	1.504652e-85	1.460660e+0	A2M,ADAM8,ANGPTL8,ASTL,BCL2L12,BIRC2,BIRC3,BIRC5,C1QA,C1QB,C1QBP,C1QC,C3,C3AR1,C4A,C4B,C4BPA,C4BPB,C5,C6,C7,C8A,C8B,C8G,C9,CARD16,CARD18,CAST,CCBE1,CD19,CD46,CD55,CD59,CD81,CFH,CFHR1,CFHR2,CFHR4,CFHR5,CFI,CFP,CHAC1,CLEC3B,CLU,CNTN2,CPB2,CPN1,CPN2,CR1,CR2,CTSZ,F12,F2,GAS1,GLG1,GSN,HPN,IFT52,IL1R2,INPP5B,KLKB1,LDLRAD3,LRRK2,MDM2,MELTF,MYH9,NAIP,NKD2,NLRC4,NLRP7,NOL3,PHB,PLGRKT,PRKACA,PROS1,RHBDD1,RNF139,SERPINE2,SERPING1,SIRT4,SNX12,SRC,SUSD4,THBS1,TMEM59,TNP1,TNP2,VTN,XIAP	TetrapodAncestor	82.1694
GO.Biological.Process	GO:0002718	regulation.of.cytokine.production.involved.in.immune.response	451	8.328298e-87	1.075766e-82	2.385291e-85	1.470603e+0	ANGPT1,APOA1,APOA2,ARG1,ATG5,BCL10,BCL6,BST2,BTK,CD226,CD36,CD74,CD96,CLC,F2RL1,FCER1G,FFAR2,FFAR3,FOXP3,FZD5,GATA3,GPRC5B,HMOX1,IFNA2,IFNB1,IL10,IL6,IRAK3,JAK3,KARS,MALT1,MAP3K7,MAPK14,MAPK3,MIF,NR4A3,PRKCZ,RSAD2,SASH3,SEMA7A,SMAD7,SPON2,TGFB1,TGFB2,TLR3,TLR4,TNF,TNFRSF14,TRAF2,TRAF6,TRIL,TRIM6,TRPM4,WNT5A,XCL1	TetrapodAncestor	81.9683
GO.Biological.Process	GO:0097485	neuron.projection.guidance	452	9.216278e-87	1.190467e-82	2.633776e-85	1.169453e+0	ALCAM,ANOS1,APBB2,APP,ARHGAP35,ARTN,ARX,ATOH1,B3GNT2,BCL11B,BDNF,BMP7,BMPR1B,BOC,CDH4,CDK5,CDK5R1,CHL1,CNTN2,CNTN4,CREB1,CRMP1,CSF1R,CXCR4,DAB1,DCC,DLX5,DOK1,DOK2,DOK4,DOK5,DOK6,DPYSL2,DPYSL4,DPYSL5,DRAXIN,DVL1,EFNA1,EFNA3,EFNA4,EFNA5,EFNB1,EFNB2,EFNB3,EGR2,ENAH,ENSG00000251246,EPHA4,EPHA5,EPHA7,EPHA8,EPHB1,EPHB2,EPHB3,ERBB2,ETV1,EVL,EXT1,EZR,FAM129B,FEZ1,FEZ2,FEZF1,FLRT2,FLRT3,FOXG1,FRS2,FZD3,GAB1,GAB2,GAP43,GATA3,GBX1,GBX2,GDNF,GFRA1,GFRA2,GFRA3,GFRA4,GLI2,GLI3,GPC1,GRB10,GRB2,GRB7,HRAS,IRS2,ISL1,ISPD,KIF5A,KIF5B,KIF5C,KIRREL1,KLF7,KRAS,L1CAM,LAMA2,LHX1,LHX2,LHX4,LMX1A,LYPLA2,MAPK1,MAPK3,MATN2,NCAM1,NECTIN1,NEO1,NFASC,NFIB,NGFR,NOG,NPHS1,NR4A3,NRAS,NRP1,NRP2,NRTN,NRXN1,NRXN3,NTN3,NTRK1,OPHN1,OR10A4,OTX2,PDLIM7,PIK3CA,PIK3CD,PIK3R1,PLA2G10,PLCG1,PLXNA1,PLXNA2,PLXNA3,PLXNA4,POU4F3,PRKCA,PRKCQ,PSPN,PTCH1,PTK2,PTPN11,PTPRA,PTPRM,PTPRO,RANBP9,RAP1GAP,RELN,RET,ROBO1,ROBO2,ROBO3,RPL24,RPS6KA5,RYK,SCN1B,SEMA3A,SEMA3C,SEMA6A,SEMA6C,SH3KBP1,SHC1,SHC3,SIAH1,SIAH2,SLIT1,SLIT2,SLIT3,SMAD4,SOS1,SPON2,SPTB,SPTBN2,SPTBN5,SRC,TNFRSF8,TNR,TUBB3,UNC5A,UNC5B,UNC5C,UNC5D,VANGL2,VASP,VEGFA,VLDLR,WNT3,WNT3A,WNT5A	TetrapodAncestor	81.9243
GO.Biological.Process	GO:0042787	protein.ubiquitination.involved.in.ubiquitin-dependent.protein.catabolic.process	453	1.099793e-86	1.420603e-82	3.135988e-85	1.308962e+0	ABTB1,ABTB2,AMFR,ANAPC1,ANAPC11,ANAPC16,ANAPC2,ANAPC4,ANAPC5,ANKIB1,ARIH1,AURKA,AURKB,BFAR,BTBD11,BTBD2,BTBD3,BTBD6,BTBD9,CACUL1,CBL,CBLC,CCIN,CCNB1,CDC16,CDC20,CDC23,CDC26,CDC27,CDK1,CUL1,CUL2,CUL3,CUL4A,CUL5,DCST1,DDB1,DTX3L,DZIP3,ELOC,FBXO10,FBXO45,FBXO7,FZR1,HACE1,HECW1,HECW2,ITCH,KBTBD4,KBTBD8,KLHL15,KLHL2,KLHL25,KLHL29,KLHL3,KLHL8,LNX1,MAD2L1,MAEA,MDM2,MYLIP,NEDD4L,OS9,PLK1,PRKN,PTTG1,RCHY1,RFFL,RMND5A,RMND5B,RNF11,RNF115,RNF122,RNF125,RNF126,RNF128,RNF14,RNF144A,RNF144B,RNF145,RNF146,RNF181,RNF185,RNF19B,RNF217,RNF24,RNF34,RNF43,RNF5,RNF7,RPS27A,SIAH1,SMURF1,SMURF2,SPOP,SPOPL,STUB1,SYVN1,TAF1,TRIM25,TRIM32,TRIM58,TRIP12,UBA6,UBC,UBE2C,UBE2D1,UBE2E1,UBE2L5P,UBR4,UHRF1,WWP1,WWP2,ZNRF2,ZNRF4	TetrapodAncestor	81.8475
GO.Biological.Process	GO:1903317	regulation.of.protein.maturation	454	1.298374e-86	1.677110e-82	3.694074e-85	1.459001e+0	A2M,ADAM8,ANGPTL8,ASTL,BCL2L12,BIRC2,BIRC3,BIRC5,C1QA,C1QB,C1QBP,C1QC,C3,C3AR1,C4A,C4B,C4BPA,C4BPB,C5,C6,C7,C8A,C8B,C8G,C9,CARD16,CARD18,CAST,CCBE1,CD19,CD46,CD55,CD59,CD81,CFH,CFHR1,CFHR2,CFHR4,CFHR5,CFI,CFP,CHAC1,CLEC3B,CLU,CNTN2,CPB2,CPN1,CPN2,CR1,CR2,CTSZ,F12,F2,GAS1,GLG1,GSN,HPN,IFT52,IL1R2,INPP5B,KLKB1,LDLRAD3,LRRK2,MDM2,MELTF,MYH9,NAIP,NKD2,NLRC4,NLRP7,NOL3,PHB,PLGRKT,PRKACA,PROS1,RHBDD1,RNF139,SERPINE2,SERPING1,SIRT4,SNX12,SRC,SUSD4,TFR2,THBS1,TMEM59,TNP1,TNP2,VTN,XIAP	TetrapodAncestor	81.7754
GO.Biological.Process	GO:0043407	negative.regulation.of.MAP.kinase.activity	455	1.376123e-86	1.777538e-82	3.906677e-85	1.418752e+0	ADIPOQ,AIDA,APOE,BMP4,BMP7,CAV1,CAV3,CBLC,CD300A,DAB2IP,DNAJA1,DUSP1,DUSP10,DUSP16,DUSP18,DUSP19,DUSP2,DUSP21,DUSP22,DUSP3,DUSP6,DUSP7,DUSP8,DUSP9,GBA,GPS1,GSTP1,HMGCR,IL1B,INPP5K,IRAK3,LAX1,LYN,MAPK8IP1,MBIP,NF1,NUP62,PRKCD,PTPN1,PTPN22,PTPRJ,RGS14,RGS2,RGS3,RGS4,SERPINB3,SFRP1,SFRP2,SMPD1,SORL1,SPRED1,SPRED2,SPRY1,SPRY2,STK38,TP73,UCHL1,ZNF675	TetrapodAncestor	81.7502
GO.Biological.Process	GO:0045638	negative.regulation.of.myeloid.cell.differentiation	456	1.481460e-86	1.913602e-82	4.196495e-85	1.389264e+0	ADIPOQ,C1QC,CARTPT,CCL3,CDC73,CDK6,CIB1,CLDN18,CTNNB1,CUL4A,DLL1,FSTL3,GABPA,GATA2,GPR171,GPR55,GPR68,HIST1H4J,HIST1H4K,HIST1H4L,HIST2H4B,HIST4H4,HMGB3,HSPA9,IL4,INHA,INHBA,INPP5D,ITPKB,KLF13,LEO1,LILRB4,LRRC17,LYN,MAFB,MEIS1,MEIS2,MYC,NF1,NME1,NME2,PAF1,PF4,PIK3R1,PRMT1,PTK2B,RARA,SFRP1,TJP2,TLR3,TLR4,TMEM178A,TRIB1,UBASH3B,WDR61,ZBTB16,ZFP36,ZFP36L1,ZFPM1,ZNF675	TetrapodAncestor	81.7181
GO.Biological.Process	GO:0050852	T.cell.receptor.signaling.pathway	457	1.826029e-86	2.358682e-82	5.161229e-85	1.341211e+0	BCAR1,BCL10,BRAF,BTRC,CARD11,CD247,CD28,CD3D,CD3E,CD3G,CHUK,CSK,CUL1,DENND1B,FBXW11,FOXP3,FYB1,FYB2,GATA3,GRAP2,HRAS,IFNG,IKBKB,IKBKG,INPP5D,ITK,LAT,LCK,LCP2,MALT1,MAP3K7,MAPK1,NCK1,NFKB1,PAG1,PAK1,PAK2,PAK3,PDE4B,PDE4D,PDPK1,PIK3CA,PIK3CD,PIK3R1,PIK3R2,PLCG1,PLCG2,PRKCQ,PRKD2,PSEN1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTPN22,PTPRJ,RBCK1,RELA,RFTN1,RIPK2,RNF31,RPS27A,SHB,SPPL3,TAB2,THEMIS,THEMIS2,THY1,TMEM189-UBE2V1,TNFRSF21,TRAF6,TRAT1,TXK,UBC,UBE2D1,UBE2D2,UBE2N,ZAP70	TetrapodAncestor	81.6273
GO.Biological.Process	GO:0050767	regulation.of.neurogenesis	458	2.385794e-86	3.081730e-82	6.728668e-85	1.102206e+0	ABCC8,ABL1,ABL2,ACTR2,ADCYAP1,ADGRB3,ADGRG1,ADNP,ADRA2B,ADRA2C,AGT,ALKAL1,ANAPC2,ANKRD1,ANKRD27,APOE,APP,ARC,ARF1,ARF6,ARHGAP35,ARHGAP4,ARHGAP44,ARHGDIA,ARHGEF2,ARNTL,ASAP1,ASCL1,ASCL2,ASPA,ASPM,ATOH1,ATP8A2,AVIL,BCL11A,BCL11B,BCL2,BCL6,BDNF,BIN1,BMP2,BMP4,BMP5,BMP6,BMP7,BMPR1A,BMPR2,BRAF,BRINP1,BRINP2,BRINP3,C16orf45,C21orf91,CALR,CAMK1,CAMK1D,CAMK2B,CAPRIN1,CAPRIN2,CARM1,CASZ1,CBFA2T2,CCDC88A,CCR2,CDC20,CDH2,CDH4,CDK1,CDK5,CDK5R1,CDK5RAP1,CDK5RAP2,CDKL5,CDON,CERS2,CFL1,CFLAR,CHD7,CHODL,CHRNA3,CHRNB2,CIB1,CLCF1,CNR1,CNTF,CNTN1,CNTN2,CNTN4,COBL,COL3A1,CPEB1,CPNE5,CPNE6,CRABP2,CREB1,CRMP1,CRX,CSF1,CSMD3,CSNK1D,CSNK1E,CTDSP1,CTNNA1,CTNNB1,CTSZ,CTTN,CUL7,CUX1,CUX2,CX3CR1,CXCR4,CYFIP1,DAB1,DAB2IP,DBN1,DCC,DCT,DDX56,DGUOK,DISC1,DISP3,DIXDC1,DKK1,DLG5,DLL1,DLL3,DLL4,DMRTA2,DNM1L,DNM2,DNMT3B,DPYSL2,DPYSL3,DRAXIN,DRD2,DRD3,DSCAM,DTX1,DUOXA1,DUSP10,DUSP15,DVL1,DYNLT1,ECT2,EDNRB,EEF2K,EFNA1,EFNA5,EFNB2,EFNB3,EIF2AK4,EIF4E,EIF4ENIF1,ELL3,EMX1,ENSG00000260272,EOMES,EPHA3,EPHA4,EPHA7,EPHB2,EPHB3,EPO,ERBB4,ETV5,EYA1,EZH2,F2,FBXO31,FBXO38,FBXO7,FBXW8,FERD3L,FES,FEZ1,FEZF1,FGF13,FGF20,FGFR1,FKBP1B,FKBP4,FLNA,FLRT2,FMR1,FN1,FOXA1,FOXG1,FOXO6,FRMD7,FSTL4,FUOM,FZD3,GAK,GATA2,GATA3,GDF5,GDF6,GDI1,GDPD5,GFAP,GJC2,GLI2,GLI3,GNRH1,GOLGA4,GPER1,GPR183,GPR37L1,GPRC5B,GRID2,GRIN1,GSK3A,HAP1,HDAC2,HES1,HES3,HES5,HEY2,HEYL,HGF,HIF1A,HMG20A,HMG20B,HMGB2,HOOK3,HSPA5,ID1,ID2,ID4,IDH2,IFNG,IFRD1,IGSF10,IL1RAP,IL1RAPL1,IL2,IL6,IL6ST,INPP5J,IQGAP1,ISL1,ISLR2,IST1,ITGA3,ITM2C,ITPKA,ITSN2,JAG1,KALRN,KANK1,KATNB1,KDM1A,KDM4C,KEL,KIAA0319,KIF13B,KIF20B,KLF4,L1CAM,LBX1,LGALS1,LIF,LIG4,LIMK1,LIN28A,LINGO1,LLPH,LMX1A,LPAR1,LPAR3,LRIG2,LRP1,LRP4,LRP8,LRRC4C,LRRC7,LRRK2,LSM1,LTK,LYN,LZTS1,LZTS3,MACF1,MAG,MAGI2,MAN2A1,MAP1B,MAP2,MAP4K4,MAPK6,MAPT,MARK2,MBD1,MCF2,MDM2,MEF2C,MEGF8,MEIS1,METRN,MIB1,MMD,MMD2,MOB2,MTOR,MUL1,MYB,MYCL,MYCN,NBL1,NCK1,NCOA1,NCS1,NDEL1,NDNF,NDRG4,NEDD4L,NEFL,NEGR1,NEPRO,NEURL1,NEUROD1,NEUROG1,NEUROG3,NF1,NF2,NFATC4,NGEF,NGF,NGFR,NIPBL,NKX2-5,NKX6-1,NLGN1,NLGN3,NME1,NME2,NOG,NOS1,NOTCH1,NOTCH3,NPTN,NRG1,NRG3,NRP1,NTF3,NTF4,NTRK1,NTRK2,NTRK3,NUMB,NUMBL,OLFM1,OLIG2,OMG,OPA1,OPRM1,OSTN,PAFAH1B1,PAK1,PAK3,PBX1,PCM1,PCP4,PDLIM5,PER2,PHOX2B,PLAA,PLAG1,PLK2,PLK5,PLPPR5,PLXNA1,PLXNA2,PLXNA3,PLXNA4,PLXNB1,PLXNB2,PLXNC1,PLXND1,PMP22,POU3F2,POU4F1,PPARG,PPP2R5B,PPP3CA,PQBP1,PREX1,PRKCH,PRKCI,PRKD1,PRKN,PRMT5,PROX1,PRPF19,PRRX1,PRUNE1,PSEN1,PTEN,PTK2,PTK2B,PTK7,PTN,PTPRD,PTPRG,PTPRO,PTPRS,PTPRZ1,RAB17,RAB21,RAB29,RAC3,RAP1A,RAP1GAP2,RAP2A,RAPGEF1,RAPGEF2,RARA,RARB,RASAL1,RELA,RELN,REST,RET,RGMA,RGS14,RHEB,RIMS1,RIT2,RND2,RNF10,RNF6,ROBO1,ROBO2,RRN3,RTN4,RTN4IP1,RTN4R,RTN4RL2,RUFY3,S1PR5,SARM1,SCARB2,SCN1B,SCRT1,SCRT2,SDC2,SDK1,SEMA3A,SEMA3G,SEMA4D,SEMA5A,SEMA6A,SEMA7A,SERPINE2,SERPINI1,SETX,SF3A2,SFRP1,SFRP2,SHANK1,SHOX2,SIPA1L1,SIRT2,SKI,SKIL,SLC39A12,SLC45A3,SLC6A4,SLIT2,SLITRK1,SMO,SMURF1,SNAP25,SNAPIN,SNW1,SOCS2,SORL1,SOX10,SOX11,SOX14,SOX2,SOX3,SOX8,SOX9,SPAG9,SPEN,SPINT1,SPOCK1,SPP1,SRCIN1,SRF,SRGAP2,SRGAP2C,SRRT,SSH2,SSH3,STAP1,STAR,STK24,STMN2,STX1B,SYNGAP1,SYT1,SYT17,SYT2,SYT4,TBX6,TCF3,TCF4,TENM3,TENM4,TERT,TGFB1,TGIF2,THOC2,THY1,TIAM1,TIMP2,TLE6,TLR2,TLX2,TLX3,TMEM106B,TNFRSF12A,TNFRSF21,TNFRSF8,TNIK,TNR,TP73,TRAK1,TRAK2,TRIM11,TRIM32,TRPC5,TRPC6,TSPO,TTL,TUBB2B,TWF2,UBE2V2,UBE3A,UFL1,ULK2,ULK4,UNC13A,UNC5D,UST,VEGFA,VEGFC,VIM,VLDLR,VWC2,VWC2L,WDR1,WDR36,WNT3,WNT3A,WNT5A,WNT7A,XK,XRCC2,XRCC5,YAP1,YWHAG,YWHAH,ZEB1,ZFYVE27,ZHX2,ZMYND8,ZNF335,ZNF365,ZNF488,ZNF609,ZNF804A	TetrapodAncestor	81.5112
GO.Biological.Process	GO:0060350	endochondral.bone.morphogenesis	459	2.579671e-86	3.332161e-82	7.259610e-85	1.419414e+0	ALPL,AXIN2,BMP4,BMP6,BMPR1B,BMPR2,CARM1,CER1,COL10A1,COL13A1,COL1A1,COL27A1,COL2A1,CSGALNACT1,DLX5,FGF18,FGFR3,FOXC1,GNAS,IHH,IMPAD1,MATN1,MEF2C,MEF2D,MMP13,MMP14,MMP16,NAB2,NPPC,PEX7,PHOSPHO1,POC1A,RARA,RARB,RARG,RUNX2,SCX,SERPINH1,SHOX2,SOX9,STC1,TEK,TGFBR2,THBS3,TRIP11	TetrapodAncestor	81.4773
GO.Biological.Process	GO:0002703	regulation.of.leukocyte.mediated.immunity	460	2.837359e-86	3.665017e-82	7.967427e-85	1.328552e+0	ABR,ADGRE2,ADORA2B,AGER,AP1G1,APLF,ARG1,ARRB2,ATAD5,BCL6,BCR,BST2,BTK,C12orf4,C3,C4BPA,C4BPB,CADM1,CCR2,CD226,CD28,CD300A,CD40,CD96,CLC,CLCF1,CLEC12B,CLEC4G,CR1,CRK,CRTAM,DUSP22,EXOSC3,EXOSC6,F2RL1,FADD,FAM49B,FCER1G,FCER2,FER,FES,FGR,FOXF1,FOXJ1,FOXP3,FZD5,GAB2,GATA2,GATA3,HAVCR2,HMGB1,HMOX1,IFNA2,IFNB1,IFNG,IL10,IL12A,IL12B,IL12RB1,IL13,IL13RA2,IL18RAP,IL1B,IL2,IL20RB,IL21,IL23A,IL23R,IL27RA,IL4,IL6,IL7R,ITGAM,ITGB2,JAK3,KLRK1,LEP,LGALS9,LYN,MALT1,MAP3K7,MLH1,MSH2,MSH6,NCR1,NCR3,NDFIP1,NECTIN2,NSD2,P2RX7,PAXIP1,PDPK1,PIK3R6,PPP3CB,PRAM1,PRKCZ,PTAFR,RAC2,RASGRP1,RIF1,RIPK3,RSAD2,SASH3,SERPINB4,SERPINB9,SH2D1A,SH2D1B,SLAMF6,SMAD7,SNX4,SPN,STAT6,STX4,STX7,STXBP1,STXBP2,STYK1,SYK,TFRC,TGFB1,THOC1,TLR3,TLR4,TNF,TNFSF13,TRAF2,TRAF6,TRPM4,UNG,VAMP8,VAV1,XCL1,ZBTB1,ZP3	TetrapodAncestor	81.4359
GO.Biological.Process	GO:0035412	regulation.of.catenin.import.into.nucleus	461	4.490859e-86	5.800843e-82	1.258317e-84	1.579635e+0	APC2,AXIN2,BAMBI,DAB2IP,DACT1,DACT3,EGF,EGFR,FERMT1,FZD1,FZD7,GNAQ,KANK1,SEMA5A,SFRP2,SFRP5,SLC9A3R1,SNAI2,SULF2,UBR5,WNT3A,WWTR1	TetrapodAncestor	81.2365
GO.Biological.Process	GO:0070301	cellular.response.to.hydrogen.peroxide	462	4.893904e-86	6.321456e-82	1.368280e-84	1.504171e+0	ABL1,AIFM1,AKR1B1,ANKZF1,ANXA1,APEX1,AQP1,ARG1,AXL,BECN1,BNIP3,CBX8,CDK1,CYP1B1,ECT2,ETS1,EZH2,FABP1,FOXO1,FXN,HDAC2,HSF1,IL18BP,IL18RAP,IL6,KDM6B,KLF2,KLF4,LCN2,MAP1LC3A,MAP3K5,MDM2,MYB,NET1,PARK7,PAX2,PCGF2,PCNA,PDCD10,PDGFD,PLEKHA1,PPIF,PPP5C,PRKAA1,PRKCD,RELA,RPS3,SETX,SIRT1,STAT6,TNFAIP3,TRPC6,TRPM2,ZNF277,ZNF580	TetrapodAncestor	81.1992
GO.Biological.Process	GO:0050864	regulation.of.B.cell.activation	463	1.162266e-85	1.501299e-81	3.242546e-84	1.329841e+0	ADA,AHR,APLF,ATAD5,ATM,ATP11C,BAD,BANK1,BCL2,BCL6,BST1,BTK,CARD11,CASP3,CD27,CD28,CD300A,CD320,CD38,CD40,CD74,CD81,CDKN1A,CHRNB2,CLCF1,CTLA4,EXOSC3,EXOSC6,FAS,FOXJ1,FOXP3,GPR183,HMGB3,IFNG,IGLL1,IGLL5,IKZF3,IL10,IL13,IL2,IL21,IL27RA,IL4,IL5,IL6,IL7,INHA,INHBA,INPP5D,IRS2,LYN,MEF2C,MIF,MLH1,MMP14,MSH2,MSH6,MZB1,NCKAP1L,NDFIP1,NFAM1,NFATC2,NSD2,PAWR,PAXIP1,PCID2,PELI1,PKN1,PPP2R3C,PRDM1,RC3H1,RIF1,SAMSN1,SASH3,SFRP1,SLA2,SLC39A10,STAT6,SYK,TBC1D10C,TFRC,TGFB1,THOC1,TICAM1,TIRAP,TLR4,TLR9,TNFAIP3,TNFRSF13B,TNFRSF13C,TNFRSF21,TNFRSF4,TNFSF13,TNFSF13B,TNIP2,UNG,VAV3,WNT3A,XBP1,ZFP36L1,ZFP36L2	TetrapodAncestor	80.8235
GO.Biological.Process	GO:0071347	cellular.response.to.interleukin-1	464	1.409056e-85	1.820078e-81	3.922581e-84	1.437923e+0	ABCC2,ADAMTS12,ADAMTS7,ANKRD1,CACTIN,CCL1,CCL11,CCL13,CCL14,CCL15,CCL15-CCL14,CCL16,CCL17,CCL18,CCL19,CCL2,CCL21,CCL22,CCL23,CCL3,CCL3L3,CCL4,CCL4L2,CCL5,CCL7,CCL8,CD40,CEBPB,CHI3L1,CX3CL1,CXCL8,DAB2IP,EDN1,EGR1,FGG,HAS2,HIF1A,IKBKB,IL17A,IL1A,IL1R1,IL1RL2,IL6,IRAK1,IRAK3,IRAK4,KLF2,LCN2,MAPK3,MYLK3,NFKB1,NKX3-1,NLRP7,OTUB1,PCK1,PLCB1,PTGIS,PYCARD,RC3H1,RELA,RPS6KA4,RPS6KA5,SFRP1,SOX9,ST18,TFPI,TNIP2,TRAF6,UPF1,USP10,XCL1,XCL2,YY1,ZC3H12A	TetrapodAncestor	80.7399
GO.Biological.Process	GO:0071260	cellular.response.to.mechanical.stimulus	465	4.534365e-85	5.857039e-81	1.259578e-83	1.411360e+0	AGT,ANKRD1,AQP1,ATP1A1,ATP1A2,BAD,BAK1,BCL10,BMP6,BNIP3,CASP1,CASP2,CASP5,CASP8,CD40,CHEK1,COL1A1,CRADD,CYBA,EGFR,ENG,FADD,FAS,GADD45A,GJA1,HABP4,HDAC4,IL13,IL1B,IRF1,ITGA2,KCNJ2,KCNK4,LTBR,MAG,MAP2K4,MAP3K1,MAP3K14,MAP3K2,MAPK3,MAPK8,MMP7,MTPN,NFKB1,PDE2A,PIEZO1,PIEZO2,PTGER4,PTPN11,RAC1,SCX,SLC2A1,SLC38A2,SLC9A1,SOX9,TGFB1,TLR3,TLR4,TLR5,TNFRSF10A,TNFRSF10B,TNFRSF1A,TNFRSF8,TNFSF14,WNT11	TetrapodAncestor	80.2323
GO.Biological.Process	GO:0002252	immune.effector.process	466	5.832486e-85	7.533822e-81	1.616700e-83	1.140196e+0	A1BG,ABCA13,ABCC9,ABCF3,ABI1,ABL1,ACE,ACPP,ACTR10,ACTR2,ACTR3,ADA,ADA2,ADAM8,ADAR,ADARB1,ADGRE3,ADGRE5,ADGRG3,AGA,AGBL4,AGBL5,AGL,AGPAT2,AHSG,AICDA,ALAD,ALDH3B1,ALDOA,ALOX5,ANO6,ANPEP,ANXA3,AOC1,AP1M1,AP2A2,APAF1,APEH,APOBEC1,APOBEC3A,APOBEC3B,APOBEC3C,APOBEC3D,APOBEC3F,APOBEC3G,APOBEC3H,APP,ARG1,ARL8A,ARPC1A,ARPC1B,ARPC2,ARPC4,ARPC5,ASAH1,ATAD3B,ATP11A,ATP11B,ATP6AP2,ATP6V0C,ATP6V1D,ATP8A1,ATP8B4,B4GALT1,BCL10,BCL2,BCL3,BECN1,BNIP3,BNIP3L,BPI,BPIFA1,BST1,BST2,BTK,C16orf62,C19orf66,C1QA,C1QB,C1QBP,C1QC,C1orf35,C3,C3AR1,C4A,C4B,C4BPA,C4BPB,C5,C6,C6orf120,C7,C8A,C8B,C8G,C8orf4,C9,CAB39,CALML5,CAND1,CANT1,CAP1,CAPN1,CAT,CBL,CCL3,CCR6,CCT2,CCT8,CD14,CD180,CD247,CD27,CD300A,CD33,CD36,CD3G,CD40,CD44,CD46,CD47,CD53,CD55,CD58,CD59,CD63,CD68,CD74,CD86,CD8A,CD93,CDA,CDC42,CDK13,CEBPG,CFH,CFHR1,CFHR5,CFI,CFP,CHGA,CHI3L1,CHIT1,CHRNB4,CKAP4,CLEC12A,CLEC2A,CLEC4C,CLEC4D,CLEC4E,CLU,CMTM6,COLEC10,COLEC11,COMMD3,COMMD9,CORO1A,COTL1,CPLX2,CPNE3,CPPED1,CR1,CR2,CRACR2A,CRCP,CREG1,CRISP3,CRISPLD2,CRK,CSNK2B,CSTB,CTSA,CTSB,CTSC,CTSD,CTSH,CTSZ,CX3CR1,CXCL1,CXCL10,CXCL5,CXCL6,CXCL9,CXCR1,CXCR2,CYB5R3,CYBA,CYBB,CYFIP1,CYFIP2,CYSTM1,DBH,DBNL,DDIT4,DDOST,DDX17,DDX3X,DDX41,DDX58,DDX60,DEGS1,DENND1B,DERA,DGAT1,DIAPH1,DLG1,DLL1,DMBT1,DNAJC13,DNASE1L1,DOCK10,DOCK11,DOCK2,DOK3,DPP7,DSC1,DSG1,DSN1,DSP,DYNC1H1,DYNC1LI1,DYNLL1,DYNLT1,EEF1A1,EEF2,EIF2AK2,EIF2AK4,ELMO1,ELMO2,ELMOD2,EMP2,ENPP4,EOMES,EPX,ERCC1,EXO1,EXOSC3,EXOSC4,EXOSC5,EXOSC6,F2,F2RL1,FABP5,FADD,FAF2,FAM111A,FAS,FCAR,FCER1G,FCN1,FCN2,FCN3,FGL2,FGR,FLG2,FOXP3,FRK,FRMPD3,FTH1,FTL,FUCA1,FUCA2,FUT7,GAA,GAPT,GATA3,GBF1,GCNT3,GDI2,GGH,GLA,GLB1,GLIPR1,GM2A,GMFG,GNL1,GNS,GOLGA7,GPAM,GPR183,GPR84,GRB2,GRN,GSDMD,GSN,GSTP1,GUSB,GYG1,HAVCR2,HBB,HCK,HEBP2,HK3,HMGB1,HMOX2,HP,HPSE,HRNR,HSP90AB1,HSPA8,IFI44L,IFIT1,IFIT1B,IFIT2,IFIT3,IFIT5,IFITM1,IFITM2,IFITM3,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNAR1,IFNAR2,IFNB1,IFNE,IFNG,IFNGR1,IFNK,IFNL1,IFNL2,IFNL3,IFNLR1,IFNW1,IGF2R,IGLL1,IGLL5,IL10RB,IL12A,IL12B,IL13RA2,IL18,IL18R1,IL18RAP,IL2,IL23A,IL31RA,IL33,IL4,IL6,ILF2,ILF3,IMPDH1,INPP5D,IQGAP1,IRAK4,IRF1,IRF2,IRF3,IRF4,IRF7,IRF9,ISG15,ISG20,IST1,ITCH,ITFG2,ITGAM,ITGAV,ITGAX,ITGB2,ITM2A,JAG1,JAGN1,JUP,KARS,KCNAB2,KCNJ8,KDELR1,KLRC2,KLRD1,KLRF2,KLRK1,KMT2E,KPNB1,KRT1,LAIR1,LAMTOR2,LAMTOR3,LAT,LAT2,LBP,LCN2,LCP1,LEF1,LFNG,LGALS1,LGALS3,LIG4,LILRB2,LIMK1,LRG1,LRMP,LRP1,LRRC7,LYN,LYZ,MAN2B1,MANBA,MAP3K14,MAPK1,MAPK14,MAPK3,MASP1,MASP2,MB21D1,MBL2,MCEMP1,MFNG,MGAM,MGST1,MIF,MILR1,MLEC,MLH1,MME,MMP25,MMP8,MMP9,MOSPD2,MPO,MS4A3,MSH2,MSH6,MVP,MX1,MX2,MYO10,MYO1C,MYO1G,NAPRT,NBEAL2,NBN,NCBP3,NCK1,NCKAP1,NCKAP1L,NCSTN,NDUFC2,NFAM1,NFASC,NFKB1,NHLRC3,NIT2,NKX2-3,NLRC5,NLRP9,NME2,NOTCH2,NPC2,NR4A3,NRAS,NT5C3A,OAS1,OASL,OLFM4,OLR1,OPRK1,ORM1,ORM2,ORMDL3,OSCAR,OSTF1,PADI2,PAFAH1B2,PAK1,PCBP2,PDAP1,PDXK,PECAM1,PFKL,PGAM1,PGLYRP1,PGM2,PGRMC1,PIGR,PIK3CA,PIK3CD,PIK3CG,PIK3R1,PIK3R2,PKM,PKP1,PLA2G1B,PLA2G3,PLA2G6,PLAC8,PLAU,PLCG1,PLCG2,PLCL2,PLD1,PLD2,PLEKHO2,PLPP4,PLSCR1,PMAIP1,PML,PNP,POLR3A,POLR3B,POLR3C,POLR3D,POLR3E,POLR3F,POLR3K,POU2F2,PPBP,PPIE,PQBP1,PRCP,PRDX1,PRDX4,PRG2,PRG3,PRKCD,PRKCE,PRSS2,PRSS3,PSAP,PSEN1,PSMA2,PSMB1,PSMB7,PSMC2,PSMC3,PSMD1,PSMD11,PSMD13,PSMD2,PSMD3,PSMD7,PTAFR,PTGER4,PTGES2,PTK2,PTK2B,PTPRB,PTPRJ,PTPRN2,PTX3,PYCARD,PYGB,QPCT,QSOX1,RAB14,RAB18,RAB24,RAB27A,RAB31,RAB37,RAB3D,RAB44,RAB4B,RAB5B,RAB6A,RAB7A,RAB9B,RAC1,RAET1E,RAET1G,RAET1L,RAP1A,RAP1B,RAP2B,RAP2C,RASGRP1,RC3H1,RC3H2,RELA,RELB,RETN,RFTN1,RGCC,RHOG,RIOK3,RNASEL,RNASET2,RNF168,RNF8,RORC,RPS6,RSAD2,RTP4,S100A11,S100A12,S100A13,S100A7,S100A8,S100A9,S100P,SAMHD1,SDCBP,SELENOK,SELL,SEMA4A,SERINC3,SERINC5,SERPINA1,SERPINA3,SERPINB1,SERPINB10,SERPINB12,SERPINB3,SERPINB6,SERPINB9,SERPING1,SETD2,SH2D1B,SIGLEC9,SIRPA,SIRPB1,SLA2,SLAMF6,SLC11A1,SLC15A4,SLC27A2,SLC2A3,SLC44A2,SLCO4C1,SLFN11,SLPI,SNAP23,SNAP25,SNAP29,SPON2,SRC,SRP14,STAT1,STAT2,STAT6,STBD1,STK11IP,STOM,STXBP2,SURF4,SUSD4,SVIP,SYK,SYNGR1,TARM1,TBC1D10C,TBK1,TCIRG1,TCN1,TICAM1,TICAM2,TIMP2,TLR2,TLR3,TLR4,TMBIM1,TMC6,TMEM173,TMEM63A,TNFAIP6,TNFRSF1B,TNFSF18,TOLLIP,TOM1,TRAPPC1,TREM1,TRIM11,TRIM22,TRIM25,TRIM34,TRIM5,TRPM2,TTR,TUBB,TUBB4B,TXNDC5,UBR4,ULBP1,ULBP2,ULBP3,UNC93B1,VAMP2,VAMP8,VAPA,VAT1,VAV1,VAV2,VAV3,VCL,VCP,VNN1,VSIG4,WASF2,WDR1,WIPF2,WIPF3,XRCC5,XRCC6,YES1,YPEL5,ZC3H12A,ZC3HAV1,ZFPM1,ZP3	TetrapodAncestor	80.123
GO.Biological.Process	GO:0046580	negative.regulation.of.Ras.protein.signal.transduction	467	1.838922e-84	2.375336e-80	5.086372e-83	1.481162e+0	ADRA1A,ARAP3,ARHGAP35,ARHGAP42,ARHGAP44,BCL6,CCDC125,CUL3,DAB2IP,DLC1,EPHB2,FBP1,FLCN,ITGA3,ITGB1,KANK1,KCTD13,MAPKAP1,MET,MFN2,NF1,NUP62,PPP2CB,RAPGEF1,RASA1,RASA2,RASA3,RASA4B,RASAL1,RASAL2,RASAL3,RIPOR2,SCAI,SPRY1,SPRY2,STAMBP,STMN1,SYNGAP1,TGFB2,TIMP2,TNFAIP1	TetrapodAncestor	79.6243
GO.Biological.Process	GO:0046718	viral.entry.into.host.cell	468	2.319249e-84	2.995774e-80	6.401226e-83	1.446199e+0	ACE2,ANPEP,AXL,CAV1,CAV2,CCR5,CD209,CD46,CD55,CD80,CD81,CD86,CDHR3,CDK1,CLDN1,CLDN6,CLDN9,CLEC4G,CLEC4M,CR1,CR2,CTSB,CXADR,CXCR4,DYNLT1,EFNB2,EFNB3,EGFR,EPHA2,EPS15,F11R,GAS6,GRK2,HAVCR1,HTR2A,IDE,ITCH,ITGA2,ITGA5,ITGAV,ITGB1,ITGB5,ITGB7,KPNA3,LDLR,MRC1,NCAM1,NECTIN1,NECTIN2,NECTIN4,NPC1,NUP153,RPSA,SCARB1,SCARB2,SERPINB3,SLC10A1,SLC1A5,SLC52A1,SLC52A2,TFRC,TNFRSF14,TNFRSF4,TYRO3,UVRAG,VAMP8,VPS18,WWP1,WWP2,XPR1,ZNF639	TetrapodAncestor	79.5235
GO.Biological.Process	GO:0002040	sprouting.angiogenesis	469	2.339016e-84	3.021307e-80	6.442019e-83	1.393323e+0	ACVRL1,ADGRA2,ANGPT1,BMP4,BMPER,CCBE1,CDC42,CDH13,DLL1,E2F7,E2F8,EFNB2,EGR3,EPHA2,EPHB4,ESM1,FGF2,FLT4,GPLD1,GREM1,ITGB1,JMJD6,LEF1,LOXL2,NOTCH1,NR4A1,NRP1,OTULIN,PTK2B,RAMP2,RNF213,ROBO1,RSPO3,SEMA3E,SEMA5A,SLIT2,SRF,TDGF1,TEK,THBS1,VEGFA	TetrapodAncestor	79.5198
GO.Biological.Process	GO:0061008	hepaticobiliary.system.development	470	2.828633e-84	3.653745e-80	7.773926e-83	1.288470e+0	AACS,ACAT1,ADA,ANXA1,ARF6,ARG1,ARID5B,ASNS,AURKA,BAAT,CCDC40,CCND1,CEBPA,CEBPB,CEBPG,CITED2,CLDN1,COBL,CPB2,CPS1,CSNK2A1,CSNK2A2,CSNK2B,CUL3,CYP1A1,DBP,DNAAF1,E2F7,E2F8,EGFR,EPHX1,EZH2,FPGS,GATA6,GFER,GLI3,GNPNAT1,HAMP,HES1,HGF,HHEX,HLX,HMGCL,HMGCS1,HMOX1,HNF1B,HNRNPD,IGF2R,IHH,IL10,ITGA2,JARID2,JUN,KRAS,LSR,MAN2A1,MKS1,MPST,NF1,NIPBL,NOTCH1,NPHP3,ONECUT1,OTC,PCNA,PHF2,PIK3CA,PKD1,PKD2,PKM,PNPT1,PRMT5,PROC,PROX1,PTCD2,PTCH1,PTN,PTPN3,QDPR,RAP1A,RARA,RB1CC1,RELA,RGN,RHBDD3,RPS16,RPS6KA1,SEC63,SOX17,SOX9,SRD5A1,SRSF1,SRSF5,SULF2,TGFB1,TYMS,UCP2,UGT1A1,UPF2,VTN,WDR35,WNT1,WNT4,XBP1,ZIC3	TetrapodAncestor	79.4373
GO.Biological.Process	GO:0003205	cardiac.chamber.development	471	3.213729e-84	4.151174e-80	8.813532e-83	1.216050e+0	ADAMTS1,ADGRG6,ANK2,AP2B1,ARID1A,BMP10,BMP4,BMP5,BMP7,BMPR1A,BMPR2,C5orf42,CAV3,CCM2L,CHD7,CITED2,COL11A1,CRELD1,CYR61,DAND5,DCTN5,DHRS3,DLL4,DNM2,DSP,EGLN1,ENG,FGFR2,FGFRL1,FHL2,FKBP1A,FOXC1,FOXC2,FOXF1,FOXH1,FRS2,FZD1,FZD2,GATA3,GATA4,GATA6,GRHL2,GSK3A,HAND1,HAND2,HEG1,HES1,HEY1,HEY2,HEYL,HIF1A,ISL1,JAG1,KCNK2,LMO4,LUZP1,MAML1,MDM2,MEF2C,MESP1,MSX2,MYBPC3,MYH6,MYH7,MYL3,MYOCD,NDST1,NKX2-5,NOG,NOTCH1,NOTCH2,NPHP3,NPRL3,NPY2R,NPY5R,NRG1,NRP1,NRP2,NSD2,OVOL2,PAX8,PCSK5,PITX2,PKP2,PLXND1,POU4F1,PPP1R13L,PRDM1,PROX1,PTCD2,PTK7,RARA,RARB,RBP4,RBPJ,RXRA,RYR2,SCN5A,SEMA3C,SFRP2,SHOX2,SMAD4,SMAD7,SMO,SNX17,SOS1,SOX11,SOX4,SRF,STRA6,SUFU,TAB1,TBX1,TBX2,TBX20,TBX3,TBX5,TEK,TGFB1,TGFB2,TGFBR1,TGFBR2,TMEM65,TNNC1,TNNI3,TNNT2,TRIP11,VANGL2,WNT11,WNT5A,ZBTB14,ZFPM1,ZFPM2	TetrapodAncestor	79.3818
GO.Biological.Process	GO:0034329	cell.junction.assembly	472	3.841995e-84	4.962705e-80	1.051421e-82	1.303578e+0	ACTN1,ACTN4,AJUBA,ANK2,APC,ARHGAP6,ARHGEF7,ARL2,BCL2,CD151,CD9,CDC42,CDH5,CLDN1,CLDN19,CLDN3,CLDN5,CRB3,CTNNA1,CTNNB1,CTTN,DLC1,DLG1,DLG5,DSG1,ECT2,ENSG00000259753,EPB41L3,F11R,FBF1,FERMT2,FLCN,FLNA,FN1,FRMPD2,FSCN1,GJA1,GJA4,GJC1,GJD3,GRHL2,HDAC7,HEG1,HIPK1,ITGA2,ITGA5,ITGB4,JUP,KRT14,KRT5,LAMA3,LAMA5,LAMB3,LIMS2,LSR,MARVELD2,MARVELD3,MTDH,MYO9A,NFASC,NR1H4,OCLN,OPHN1,PARD3,PARD6A,PARD6B,PARD6G,PATJ,PDCD6IP,PDPK1,PIP5K1A,PIP5K1C,PKP2,PKP3,PLEC,POF1B,PRKCA,PRKCI,PTK2B,PTPRK,PTPRO,RAB13,RAMP2,RCC2,RHOC,RHOD,SH3BP1,SMAD7,SORBS1,SRF,STRN,TAOK2,TBCD,TESK2,THY1,TJP1,TLN1,TNS1,TRIP6,UGT8,VASP,VCL,VMP1,WDR1,WNT11,ZNF703	TetrapodAncestor	79.3043
GO.Biological.Process	GO:0048661	positive.regulation.of.smooth.muscle.cell.proliferation	473	3.995957e-84	5.161578e-80	1.091243e-82	1.375166e+0	AGT,AIF1,AKR1B1,BMP4,BMPR1A,CALCRL,CCL5,CDH13,CYBA,EDN1,EGFR,EREG,ERN1,FGFR2,HBEGF,HDAC4,HES5,HMGCR,HMOX1,HPGD,HTR1B,ID2,IGF1,IL10,IL13,IL18,IL6,IL6R,IRAK1,IRAK4,ITGA2,JAK2,JUN,MAP3K5,MDM2,MMP9,MTOR,MYB,NAMPT,NOTCH3,NPY5R,NQO2,NR4A3,PAK1,PDGFB,PDGFD,PDGFRB,PPARGC1A,PTAFR,RBPMS2,RETN,S1PR1,SKP2,STAT1,TERT,TGFBR2,TGM2,THBS1,TNF,TRAF6	TetrapodAncestor	79.2872
GO.Biological.Process	GO:0060349	bone.morphogenesis	474	4.504776e-84	5.818819e-80	1.227599e-82	1.304871e+0	ACP5,ALPL,AXIN2,BMP4,BMP6,BMPR1B,BMPR2,CARM1,CDX1,CER1,COL10A1,COL13A1,COL1A1,COL27A1,COL2A1,CSGALNACT1,CYP26B1,DCANP1,DHRS3,DLX5,FGF18,FGF4,FGFR2,FGFR3,FOXC1,FOXN3,FREM1,GLG1,GLI3,GNAS,HAS2,IFITM5,IHH,IMPAD1,INSIG2,LRP5,MATN1,MEF2C,MEF2D,MEGF8,MMP13,MMP14,MMP16,MSX1,MSX2,NAB2,NEUROG1,NPPC,PAPPA2,PEX7,PHOSPHO1,POC1A,RAB23,RARA,RARB,RARG,RIPPLY1,RIPPLY2,RUNX2,SCX,SERPINH1,SFRP2,SFRP4,SHOX2,SKI,SOX9,STC1,T,TEK,TFAP2A,TGFB1,TGFBR2,THBS3,TIFAB,TRIP11,TWIST1	TetrapodAncestor	79.2352
GO.Biological.Process	GO:0034620	cellular.response.to.unfolded.protein	475	5.699654e-84	7.362243e-80	1.549946e-82	1.430374e+0	ACADVL,ADD1,AMFR,ASNA1,ASNS,ATF3,ATF4,ATF6,ATF6B,ATP6V0D1,BAK1,BAX,BHLHA15,CALR,CCL2,CCND1,CREB3,CREB3L1,CREB3L2,CREB3L3,CREBRF,CTDSP2,CTH,CUL7,CXCL8,CXXC1,DAB2IP,DAXX,DCTN1,DDX11,DERL1,DERL2,DERL3,DNAJB11,DZIP3,EDEM1,EDEM2,EDEM3,EIF2AK2,EIF2AK3,EP300,ERN1,ERO1A,EXTL1,EXTL2,EXTL3,FGF21,FKBP14,GFPT1,GOSR2,GSK3A,HDGF,HERPUD1,HSF1,HSP90B1,HSPA5,HYOU1,IFNG,KDELR3,KLHDC3,LMNA,MBTPS1,MBTPS2,MYDGF,OPTN,PACRG,PARP16,PDIA6,PLA2G4B,PPP1R15A,PPP2R5B,PREB,PRKN,PTPN1,RHBDD1,RNF121,RNF175,SEC61A1,SEC61A2,SEC61B,SEC61G,SEC62,SEC63,SERP1,SERP2,SHC1,SRPRA,SRPRB,SSR1,STC2,STUB1,SYVN1,TBL2,TLN1,TM7SF3,TPP1,UGGT1,VAPB,VCP,WFS1,WIPI1,XBP1,YOD1,ZBTB17	TetrapodAncestor	79.133
GO.Biological.Process	GO:0045621	positive.regulation.of.lymphocyte.differentiation	476	6.698817e-84	8.652862e-80	1.817828e-82	1.358578e+0	ADA,ADAM8,ANXA1,AP3D1,ATP11C,AXL,BAD,BCL6,BTK,CCL19,CD27,CD46,CD74,CD80,CD83,CD86,DUSP10,FLT3LG,FOXP3,GAS6,GATA3,GLI2,GLI3,HLX,IFNG,IHH,IL12A,IL12B,IL12RB1,IL15,IL18,IL1RL2,IL2,IL23A,IL23R,IL36B,IL4,IL6,IL7,IL7R,INPP5D,ITPKB,LGALS9,LILRB2,LILRB4,MMP14,MYB,NCKAP1L,PCID2,PIK3R6,PNP,PPP2R3C,PRDM1,PRKCZ,RAG1,RARA,RASGRP1,RIPK2,SART1,SASH3,SHB,SOCS1,SOCS5,SYK,TESPA1,TGFB1,TGFBR2,TNFSF9,VNN1,XBP1,ZAP70,ZBTB1,ZBTB16,ZMIZ1	TetrapodAncestor	79.0628
GO.Biological.Process	GO:0036293	response.to.decreased.oxygen.levels	477	7.432939e-84	9.601127e-80	2.012815e-82	1.199033e+0	ABAT,ABCB4,ACAA2,ACTN4,ACVRL1,ADA,ADAM8,ADIPOQ,ADORA1,ADSL,AGER,AGTRAP,AHCY,AIFM1,AJUBA,ALAD,ALDH3A1,ANGPT2,ANGPT4,ANGPTL4,ANKRD1,APAF1,APOLD1,AQP1,AQP3,ARNT2,ASCL2,ATM,ATP1B1,BACH1,BAD,BCL2,BECN1,BIRC2,BMP2,BMP7,BNIP3,BNIP3L,BRIP1,CA9,CAPN2,CARD16,CASP1,CASP3,CASR,CAT,CAV1,CBL,CCL2,CCNA2,CCNB1,CD24,CD38,CDKN1B,CFLAR,CHRNB2,CITED2,CLCA1,CLDN3,COX4I2,CPEB1,CPEB2,CPEB4,CREB1,CRYAB,CTGF,CUL2,CXCR4,CYBA,CYBB,CYGB,CYP1A1,DDIT4,DNM1L,DNMT3A,DNMT3B,DRD2,E2F1,EDN1,EEF2K,EGLN1,EGLN2,EGLN3,EGR1,EIF4EBP1,ELOB,ELOC,ENDOG,EP300,EPAS1,EPO,ERCC2,ERCC3,ERO1A,ETS1,F7,FABP1,FAM162A,FIS1,FMN2,FUNDC1,GATA6,GNGT1,HIF1A,HIF1AN,HIF3A,HIGD1A,HIPK2,HMOX1,HMOX2,HSD11B2,HSF1,HSP90B1,HYOU1,IRAK1,ITGA2,ITPR1,ITPR2,KCNA5,KCND2,KCNK2,KCNK3,KCNMA1,KCNMB1,LDHA,LEP,LIMD1,LMNA,LONP1,LOXL2,MB,MDM2,MDM4,MECP2,MGARP,MMP14,MTHFR,MTOR,MYB,MYC,MYOCD,NARFL,NDNF,NDRG1,NF1,NKX3-1,NOL3,NOP53,NOS1,NOS2,NOTCH1,NOX4,NPEPPS,NPPC,NR4A2,OPA1,OPRD1,OXTR,P2RX2,P2RX3,P4HB,PAK1,PAM,PCK1,PDK3,PDLIM1,PENK,PGK1,PICK1,PINK1,PKLR,PKM,PLAT,PLAU,PLK3,PLOD2,PMAIP1,PML,PPARA,PPARD,PPARGC1A,PRKAA1,PRKCB,PRKCE,PSEN2,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTEN,PTGIS,PTK2B,PTN,RAF1,RAMP2,RBPJ,RGCC,RPS27A,RYR1,RYR2,S100B,SCFD1,SFRP1,SIRT1,SIRT2,SIRT4,SLC29A1,SLC2A8,SLC6A4,SLC8A1,SLC8A3,SLC9A1,SMAD4,SOD3,SRC,SRF,STC1,STC2,SUV39H2,TBL2,TEK,TERT,TGFB1,TGFB2,TGFBR2,TH,THBS1,TIGAR,TLR2,TM9SF4,TP53,TRPC6,TWIST1,TXN2,UBC,UBE2D1,UBE2D2,UBE2D3,UBQLN1,UCN3,UCP2,UCP3,USF1,UTS2,VCAM1,VEGFA,VEGFB,VEGFC,VEGFD,XRCC1,ZFP36L1,ZNF354A	TetrapodAncestor	79.0177
GO.Biological.Process	GO:0051047	positive.regulation.of.secretion	478	7.662950e-84	9.898233e-80	2.070760e-82	1.184789e+0	AACS,ABAT,ABL1,ACHE,ACSL3,ADAM8,ADAM9,ADCYAP1,ADORA1,ADORA2A,ADORA2B,AGT,AGTR2,ALOX15B,ANKRD1,ANO1,AP1G1,APLN,AQP1,ARF1,ARHGEF7,ARRB1,ATG5,ATP13A2,ATP6AP1,AVP,AVPR1A,BAD,BLK,BMP6,C1QTNF1,C1QTNF12,C1QTNF3,C2CD2L,C5,CACNA1G,CACNA1H,CACNA1I,CADM1,CADPS2,CAPN10,CARTPT,CASP1,CASP5,CASR,CCK,CCL19,CCL3,CD14,CD2,CD274,CD34,CD38,CD58,CDK5,CDK5R2,CFTR,CHIA,CHMP2A,CHRNB2,CHUK,CLASP1,CLASP2,CLEC4E,CLEC6A,CLEC9A,CPB2,CREB1,CRTAM,CSF1R,CYBA,CYP19A1,CYP4A11,DDX58,DHX9,DNM1L,DOC2B,DRD2,DRD3,DTNBP1,EDN1,EDN3,EDNRB,EGFR,EXPH5,EZR,F2R,F2RL1,FCER1G,FCN1,FERMT1,FFAR1,FFAR2,FGFR1,FGG,FGR,GAB2,GAL,GAPDH,GATA2,GATA3,GCK,GDNF,GHRH,GHRHR,GIP,GIPR,GJA1,GLUD1,GLUL,GOLPH3,GPER1,GPLD1,GPR68,GRK2,GRP,GSDMD,HAVCR2,HGS,HIF1A,HMGB1,HMHB1,HTR2B,IFNAR1,IFNG,IGF1,IL10,IL13,IL17A,IL17F,IL17RA,IL17RB,IL17RC,IL1A,IL1B,IL1RAP,IL1RL1,IL2,IL26,IL33,IL4,IL5,IL6,INHA,INHBA,INHBB,INS,IRF3,IRS2,ISL1,ITGAM,ITGB2,JAK2,KARS,KCNB1,KIF5B,KISS1,LACRT,LEP,LGALS9,LPL,MAP2K6,MAPK11,MAPK14,MAPK3,MCU,MIF,MMP12,MPC2,MYB,MYO18A,MYRIP,NCS1,NKX3-1,NKX6-1,NLGN1,NLRP1,NLRP10,NLRP2,NNAT,NPR1,NPY2R,NR0B2,NR1H2,NR1H4,NTSR1,OPRK1,OPRL1,OR51E2,ORM1,ORM2,OXCT1,OXT,OXTR,P2RX4,P2RX7,P2RY1,P2RY2,PAEP,PANX1,PCK2,PDCD6IP,PFKFB2,PHPT1,PINK1,PLA2G10,PLA2G1B,PLA2G6,PLAA,PPARD,PPP3CB,PRKCE,PRKCZ,PSMD9,PTAFR,PTGER4,PTPN11,PTPN22,PTPN23,PYCARD,PYDC1,RAB15,RAB27A,RAB27B,RAB2B,RAB3D,RAB3GAP1,RAB5A,RAB7A,RAB8B,RASGRP1,RASL10B,RBP4,RETN,RFX6,RGCC,RIPK2,RPH3AL,S100A8,SAA1,SCAMP5,SCIN,SCT,SDC4,SDCBP,SELENOK,SELENOT,SERP1,SIRT3,SLC30A8,SLC6A4,SMAD4,SMPD3,SNCA,SNF8,SNX4,SOX11,SOX4,SPP1,SRC,SRI,STAM,STX1A,STX1B,STX4,STXBP1,STXBP5,STXBP5L,SYBU,SYK,SYT1,SYT10,SYT4,SYT7,SYT9,SYTL2,SYTL4,TAC1,TAC4,TARDBP,TFR2,TGFB1,TGFB2,TLR1,TLR2,TLR4,TM7SF3,TMEM27,TNF,TNFRSF11A,TNFRSF14,TNFRSF4,TNFSF11,TRIM6,TRPM4,TRPV1,TSG101,TTN,TWIST1,UCN,UCN3,UNC13A,UNC13B,VAMP8,VEGFC,VPS35,VPS4A,VPS4B,VSNL1,VTCN1,WLS,WNT5A,XBP1,ZP3	TetrapodAncestor	79.0044
GO.Biological.Process	GO:0001667	ameboidal-type.cell.migration	479	8.044506e-84	1.039109e-79	2.169330e-82	1.247267e+0	ABL1,ADGRA2,ALX1,AMOT,AMOTL1,ANLN,APELA,APOA1,ARID5B,CAP1,CDH13,CER1,CFL1,CORO1B,CRB2,CXCL13,CYP1B1,EDN3,EDNRB,EFNB1,EFNB2,EGR3,EMP2,EPB41L5,EPHB4,ERBB4,FAT2,FERMT1,FGF10,FGF19,FGF2,GBX2,GDNF,GIPC1,GPLD1,GREM1,HAND2,HIF1A,HMGB1,HTR2B,ID1,ISL1,ITGA4,ITGB1,ITGB2,ITGB7,KITLG,KRT16,KRT2,LAMA5,LEF1,LGALS8,LOXL2,LRP5,LTB4R2,MEGF8,MESP1,MIXL1,MYH9,NANOS1,NOS3,NOV,NR4A1,NRP1,NRTN,NUP188,OVOL2,PAFAH1B1,PAXIP1,PHACTR4,PHOX2B,PIK3CA,PIP5K1A,PITX2,PKN1,PLEKHG5,PLXND1,PML,PPARD,PRKX,PRSS3,PTEN,PTK2,PTK2B,PTP4A3,PTPN11,PXN,RAB13,RET,RIC8A,ROBO1,S100A2,S100P,SCARB1,SCG2,SEMA3A,SEMA3C,SGPL1,SLIT2,SMO,SOX10,SOX17,SOX18,SOX8,SRF,SRGAP2,STARD13,SYNE2,T,TBX1,TDGF1,TGFBR1,TMEM201,TNFSF12,TNS1,TWIST1,VEGFA,VHLL,WASF2,WNT11,WNT5A,ZFAND5	TetrapodAncestor	78.9833
GO.Biological.Process	GO:0008610	lipid.biosynthetic.process	480	8.495119e-84	1.097315e-79	2.286072e-82	1.155756e+0	A3GALT2,A4GALT,ABCD3,ABHD5,ABO,ACAA2,ACACA,ACACB,ACAT2,ACBD3,ACER1,ACER2,ACER3,ACHE,ACOT7,ACOT8,ACOX2,ACP6,ACSL1,ACSL3,ACSM1,ACSM2A,ACSM2B,ACSM3,ACSM4,ACSM5,ACSM6,ACSS1,ACSS2,AGK,AGMO,AGPAT1,AGPAT2,AGPAT3,AGPAT4,AGPAT5,AJUBA,AKR1B1,AKR1D1,ALDH1A3,ALDH3A2,ALDH3B1,ALDH3B2,ALDH8A1,ALOX15,ALOX15B,ALOX5,ALOX5AP,ALPI,AMACR,APOA1,APOA2,APOA4,APOA5,ARF1,ARF3,ARV1,ATM,B3GALT2,B3GALT4,B3GNT5,B4GALNT1,B4GALT3,B4GALT6,BAAT,BCO1,BMX,BRCA1,CACNA1H,CBR1,CBR4,CD74,CDIPT,CDS1,CDS2,CEPT1,CERKL,CERS1,CERS2,CERS3,CERS4,CERS5,CES1,CFTR,CH25H,CHAT,CHKA,CHPT1,CLN8,CNBP,COQ2,CPNE3,CPNE6,CPNE7,CRABP2,CRLS1,CSNK1G2,CSNK2A1,CSNK2A2,CSNK2B,CWH43,CYB5R1,CYB5R2,CYB5R3,CYP11A1,CYP11B1,CYP11B2,CYP17A1,CYP19A1,CYP1A1,CYP27A1,CYP27B1,CYP39A1,CYP46A1,CYP7A1,CYP8B1,DDHD1,DDHD2,DEGS1,DEGS2,DGAT1,DGAT2,DGKA,DGKE,DGKQ,DHCR24,DHCR7,DHDDS,DHRS11,DOLPP1,DPAGT1,DPM1,DPM2,DPM3,EDN1,EDN2,ELOVL1,ELOVL2,ELOVL3,ELOVL4,ELOVL6,ELOVL7,ENSG00000260300,ETNK1,ETNK2,ETNPPL,FA2H,FABP5,FADS1,FADS2,FADS3,FADS6,FAM213B,FAM57B,FAR1,FASN,FAXDC2,FDFT1,FDPS,FDX1,FDXR,FGF1,FGF10,FGF16,FGF17,FGF18,FGF19,FGF2,FGF20,FGF22,FGF23,FGF3,FGF4,FGF6,FGF7,FGF9,FGFR1,FGFR2,FGFR3,FGFR4,FITM1,FITM2,FRS2,FSHB,G6PD,GAB1,GAL3ST1,GAL3ST2,GAL3ST3,GAL3ST4,GBA,GBGT1,GGT1,GGT2,GGT5,GGT7,GGTLC2,GGTLC3,GK,GLT6D1,GPAA1,GPAM,GPAT4,GPD1,GPD1L,GRB2,HACD1,HACD2,HACD3,HACD4,HDHD5,HINT2,HMGCR,HMGCS1,HMGCS2,HPGDS,HSD11B1,HSD11B2,HSD17B1,HSD17B12,HSD17B3,HSD17B4,HSD17B7,HSD17B8,HSD3B1,HSD3B2,HSD3B7,IMPA1,INPP4A,INPP4B,INPP5D,INPP5J,INPP5K,INSIG2,IRS1,IRS2,ISPD,KDSR,KL,LARGE1,LBR,LCAT,LCLAT1,LHB,LIPH,LPCAT4,LPIN1,LPIN3,LPL,LSS,LTC4S,MBOAT1,MBOAT7,MCAT,MECR,MFSD2A,MGLL,MGST2,MGST3,MIF,MLYCD,MOGAT2,MPPE1,MTM1,MTMR1,MTMR12,MTMR2,MTMR3,MTMR4,MTMR6,MTMR8,MTMR9,MVD,NDUFAB1,NPC1L1,NR0B1,NSDHL,NUS1,OCRL,OLAH,OSBP,OSBPL2,OSBPL3,OSBPL9,OXSM,P2RX7,PBX1,PCK1,PCTP,PCYT1A,PCYT1B,PCYT2,PDSS2,PECR,PEMT,PEX7,PGAP1,PGAP2,PGAP3,PGS1,PHOSPHO1,PI4K2A,PI4K2B,PI4KB,PIGA,PIGF,PIGG,PIGH,PIGK,PIGM,PIGN,PIGP,PIGQ,PIGS,PIGT,PIGU,PIGW,PIGX,PIGZ,PIK3C2A,PIK3C2B,PIK3C2G,PIK3C3,PIK3CA,PIK3CD,PIK3CG,PIK3R1,PIK3R2,PIK3R3,PIK3R5,PIK3R6,PIKFYVE,PIP4K2A,PIP4K2B,PIP4K2C,PIP5K1A,PIP5K1B,PIP5K1C,PISD,PITPNM1,PITPNM3,PLA2G10,PLA2G12A,PLA2G16,PLA2G1B,PLA2G2A,PLA2G2D,PLA2G2E,PLA2G2F,PLA2G4A,PLA2G4B,PLA2G4D,PLA2G4F,PLA2G5,PLA2G6,PLCE1,PLCG2,PLD1,PLD2,PLD6,PLEKHA1,PLEKHA2,PLEKHA3,PLEKHA4,PLEKHA8,PLP1,PLPP1,PLPP2,PLPP3,PLPP6,PLSCR1,PMVK,PNPLA3,PPARD,PPM1L,PRG3,PRKAA1,PRKAA2,PRKAB1,PRKAG2,PRKAG3,PRKD1,PRKD2,PRKD3,PRLR,PRPF19,PTDSS1,PTDSS2,PTEN,PTGDS,PTGES,PTGES2,PTGIS,PTGS1,PTPMT1,PTPN11,PTPN13,QKI,RAB14,RAB4A,RAB5A,RBP1,RDH10,RDH8,RUFY1,SACM1L,SBF1,SC5D,SCD,SCP2,SCP2D1,SDR42E1,SDR42E2,SELENOI,SERAC1,SERINC1,SERINC4,SERINC5,SGMS1,SGPL1,SGPP1,SLC27A1,SLC27A2,SLC27A5,SLC44A1,SLC44A2,SLC44A3,SLC44A5,SMPD1,SMPD2,SPHK1,SPHK2,SPTLC1,SPTLC2,SPTLC3,SPTSSA,SPTSSB,SQLE,SRD5A2,SREBF1,ST3GAL2,ST3GAL4,ST3GAL5,ST6GALNAC1,ST6GALNAC5,ST6GALNAC6,ST8SIA1,ST8SIA2,ST8SIA4,ST8SIA5,ST8SIA6,STAR,STARD10,STARD3NL,STARD7,SYK,SYNJ1,SYNJ2,TAZ,TBXAS1,TECR,TECRL,TFCP2L1,THNSL2,TLR9,TM7SF2,TPTE2,TRERF1,TSPO,TSPOAP1,UGCG,UGT8,VAC14,VAPA,VAPB,XBP1	TetrapodAncestor	78.9597
GO.Biological.Process	GO:0048638	regulation.of.developmental.growth	481	9.040265e-84	1.167731e-79	2.427715e-82	1.166525e+0	ABL1,ACACB,ADNP,ADRB2,ADRB3,AFG3L2,AGR2,AGRN,AKAP6,ANAPC2,APOE,APP,AR,ARHGAP4,ARX,ATP8A2,ATRN,BASP1,BBS4,BCL11A,BCL2,BCL2L11,BDNF,BMP10,BMP4,BMPR1A,BMPR2,CACNA2D2,CARM1,CAV3,CCNB1,CDH4,CDK1,CDK4,CDK5,CDK5R1,CDKL5,CHD7,COLQ,CPNE5,CPNE6,CRABP2,CREB1,CSF1,CTDP1,CTTN,CYFIP1,DCC,DIO3,DISC1,DLL1,DNM2,DPYSL2,DRAXIN,DRD2,DRD3,DSCAM,DUSP10,DUSP6,EDN1,EFNA5,EPHA7,ERBB4,EZR,FGF13,FGF2,FGF20,FGF9,FGFR1,FGFR2,FGFR3,FLVCR1,FN1,FOXC1,FOXC2,FOXS1,FSTL4,FXN,G6PD,GAL,GATA6,GDF5,GDI1,GH1,GHR,GHRH,GHRHR,GHSR,GJA1,GOLGA4,GPAM,GPAT4,GPR21,GSK3A,HAMP,HEY2,HLX,HNF1B,HSF1,HTRA2,IFRD1,IGF1,IL7,ISLR2,IST1,ITSN2,JARID2,KCNK2,L1CAM,LATS1,LATS2,LEP,LGMN,LIMK1,LPAR3,MACF1,MAEL,MAG,MAP1B,MAPK11,MAPK14,MAPT,MEF2C,MEGF8,MEIS1,MKKS,MSTN,MTM1,MTOR,MUL1,MUSK,MYOD1,NDEL1,NEDD4L,NIPBL,NKX2-5,NKX6-1,NOG,NOTCH1,NPPC,NPY1R,NRG1,NRK,NRP1,NTRK3,OLFM1,OSTN,PAFAH1B1,PAK1,PHLDA2,PIK3CA,PIM1,PIN1,PLAA,PLAC8,PLCB1,PLS1,PLXNA1,PLXNA2,PLXNA3,PLXNA4,POR,POU1F1,POU3F2,PPARD,PPIB,PRKDC,PRKN,PRL,PRLH,PROX1,PTCH1,PTEN,PTK2,PTPN11,PTPRS,RAB21,RAG2,RAI1,RASAL1,RBP4,RBPJ,RIMS1,RND2,RNF6,RTN4,RTN4R,RUFY3,SASH3,SEMA3A,SEMA3G,SEMA4D,SEMA5A,SEMA7A,SERP1,SFRP1,SFRP2,SGPL1,SLC6A3,SLC6A4,SMO,SMURF1,SOCS2,SOD1,SOX15,SPAAR,SPP1,SRF,STC2,STK4,SYT1,SYT17,SYT2,SYT4,TBX2,TBX20,TBX5,TGFBR1,TGFBR2,TLL2,TNFRSF12A,TNKS2,TNR,TP73,TRPC5,TTL,TWF2,ULK2,UNC13A,VEGFA,VIL1,WDR36,WNT3,WNT3A,WNT5A,WWC1,WWC2,WWC3,YBX3,ZFPM2,ZFYVE27,ZP3	TetrapodAncestor	78.9327
GO.Biological.Process	GO:0048660	regulation.of.smooth.muscle.cell.proliferation	482	9.216390e-84	1.190481e-79	2.469878e-82	1.292024e+0	ADIPOQ,AGT,AIF1,AKR1B1,APOD,BMP4,BMPR1A,CALCRL,CCL5,CDH13,CDKN1B,CNN1,CTNNB1,CYBA,EDN1,EGFR,EREG,ERN1,FGFR2,GPER1,GSTP1,HBEGF,HDAC4,HES5,HMGCR,HMOX1,HPGD,HTR1B,ID2,IFNG,IGF1,IGFBP5,IL10,IL12A,IL12B,IL13,IL15,IL18,IL6,IL6R,IRAK1,IRAK4,ITGA2,JAK2,JUN,KLF4,MAP3K5,MDM2,MFN2,MMP9,MTOR,MYB,MYOCD,NAMPT,NDRG4,NOTCH3,NPPC,NPR1,NPR3,NPY5R,NQO2,NR4A3,OGN,PAK1,PDE1A,PDGFB,PDGFD,PDGFRB,PPARD,PPARG,PPARGC1A,PRKDC,PTAFR,PTGIR,RBPMS2,RETN,S1PR1,SKP2,STAT1,TERT,TGFBR2,TGM2,THBS1,TNF,TNFAIP3,TRAF6,TRIB1,VIPR2,XRCC5,XRCC6	TetrapodAncestor	78.9243
GO.Biological.Process	GO:0031214	biomineral.tissue.development	483	1.191014e-83	1.538433e-79	3.185161e-82	1.397848e+0	ALOX15,ALPL,AMELX,ANO6,ASPN,AXIN2,BGLAP,BMP2,CEMP1,CER1,CLEC3B,CNNM4,COL1A1,CYP27B1,DDR2,DMP1,DSPP,DUOX2,EIF2AK3,ENPP1,ERCC2,FAM20A,FAM20C,FAM83H,FBXL15,FGFR2,FGFR3,FOXO1,GPC3,GPNMB,IBSP,IFITM5,IGF1,KLF10,LEP,LGR4,MEPE,MINPP1,MMP13,MSX2,NECTIN1,OTOP1,PHEX,PHOSPHO1,PKDCC,PPARA,PTH1R,PTN,ROR2,RSPO2,SBDS,SPP1,STIM1,TBX1,TFIP11,TUFT1,WDR72,WNT11,ZBTB40	TetrapodAncestor	78.8129
GO.Biological.Process	GO:0044419	interspecies.interaction.between.organisms	484	1.416155e-83	1.829247e-79	3.779437e-82	1.154976e+0	AAAS,ABI1,ABI2,ACE2,ACKR3,ACOT8,ACY3,ALB,ALYREF,AMBP,ANKRD17,ANPEP,AP1G2,APOA2,APOBEC3C,APOBEC3G,APOE,AQP1,ATF7,ATF7IP,ATG16L1,ATG16L2,ATG5,ATP6V0C,AXL,AZI2,BAD,BANF1,BAX,BCL2L1,BCL2L11,BECN1,BICD1,BIN1,BNIP3,BNIP3L,BRD4,BTRC,BUB1,C14orf166,C1QBP,C9,CARM1,CASP8,CAV1,CAV2,CBL,CBLL1,CCDC86,CCL1,CCL2,CCL3,CCL4,CCL5,CCNA2,CCNK,CCNT2,CCR2,CCR3,CCR5,CD1D,CD200R1,CD209,CD46,CD55,CD80,CD81,CD86,CD93,CDC25C,CDC42,CDH1,CDHR3,CDK1,CDK13,CEBPA,CENPA,CENPU,CFH,CFL1,CFLAR,CHD1,CHD6,CHMP1A,CHMP1B,CHMP2A,CHMP2B,CHMP3,CHMP4A,CHMP4B,CHMP4C,CHMP5,CHMP6,CHMP7,CLDN1,CLDN6,CLDN9,CLEC4G,CLEC4M,CPSF4,CR1,CR2,CREB1,CREB3,CRTC3,CTBP1,CTDP1,CTNNB1,CTNND1,CTSB,CUL1,CUL2,CUL4A,CUL5,CUL7,CX3CR1,CXADR,CXCR4,CXCR6,DAXX,DCAF1,DDB1,DDX11,DDX3X,DDX58,DEK,DERL1,DHX9,DLG1,DMBT1,DYNC1LI1,DYNLL1,DYNLT1,DYRK1A,E4F1,EEA1,EFNB2,EFNB3,EGFR,EIF2AK2,EIF2AK4,EIF2D,EIF3A,EIF3B,EIF3D,EIF3F,EIF3L,EIF4A1,EIF4A2,EIF4E,EIF4H,ELOC,EP300,EPHA2,EPS15,ERCC2,ERCC3,F11R,F2,FADD,FAM111A,FBLN1,FBXL2,FBXW7,FDPS,FMR1,FN1,FURIN,GADD45GIP1,GAPDH,GAS6,GBF1,GRB2,GRK2,GTF2A2,GTF2E1,GUCY1A3,H2AFX,HAVCR1,HCFC1,HCFC2,HDAC1,HIPK2,HMGA2,HNRNPK,HPN,HSP90AB1,HSPA8,HTR2A,IDE,IFIT1,IK,IKBKG,IL16,IL2RB,IL2RG,IL6ST,INPP5K,IPO5,IRF3,IRF7,IRGM,ISG15,IST1,ITCH,ITGA2,ITGA5,ITGAV,ITGB1,ITGB5,ITGB7,ITSN1,IVNS1ABP,JUN,KARS,KAT2B,KAT5,KCTD5,KPNA1,KPNA2,KPNA3,KPNA4,KPNA5,KPNA7,KPNB1,KRT19,KRT6A,KRT7,LDLR,LEF1,LIG4,LMBRD1,LRRC15,LRSAM1,LTBR,LYN,MAGI3,MAP3K5,MAPK1,MAPK3,MBL2,MCTS1,MDM2,MECP2,MET,MFGE8,MMP1,MON1B,MPDZ,MRC1,MRE11,MSH6,MVB12A,NCAM1,NCKAP1,NDC1,NECTIN1,NECTIN2,NECTIN4,NEDD4L,NFIA,NFX1,NLRP1,NLRX1,NMT2,NPC1,NPM1,NTRK3,NUCKS1,NUP107,NUP153,NUP155,NUP160,NUP188,NUP205,NUP214,NUP35,NUP37,NUP43,NUP50,NUP54,NUP58,NUP62,NUP85,NUP88,NUP98,NUPL2,NXF1,PAAF1,PABPN1,PACS2,PARD6A,PC,PCBP1,PCBP2,PCSK5,PDCD6IP,PDCL3,PDZD8,PF4,PGLYRP1,PGLYRP2,PGLYRP3,PIK3C2G,PIK3R1,PLCG1,PLG,PML,POM121,POM121C,POU2F3,PPIB,PRKN,PRMT6,PSIP1,PSMA3,PSMA4,PSMB1,PSMB10,PSMB3,PSMB4,PSMB5,PSMB7,PSMC2,PSMC3,PTX3,RAB11FIP4,RAB1A,RAB29,RAB43,RAB5A,RAB6A,RAB7A,RAD23A,RAD50,RAE1,RAET1G,RAET1L,RALA,RANBP2,RB1,RBCK1,RBL1,RBM15B,RCC1,RCOR1,RELA,REST,RNF216,RNGTT,ROCK2,RPL10A,RPL11,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL17,RPL18,RPL18A,RPL19,RPL23,RPL23A,RPL24,RPL27,RPL28,RPL29,RPL3,RPL30,RPL31,RPL34,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL5,RPL6,RPL7,RPL7A,RPL8,RPLP0,RPLP2,RPS11,RPS12,RPS13,RPS14,RPS15,RPS15A,RPS16,RPS17,RPS18,RPS20,RPS21,RPS23,RPS24,RPS25,RPS26,RPS27,RPS27A,RPS28,RPS29,RPS3,RPS4X,RPS5,RPS6,RPS7,RPS8,RPSA,RRAGA,RRP1B,RSAD2,RTN3,RXRA,SATB1,SCARB1,SCARB2,SCRIB,SERINC5,SERPINB3,SERPINB9,SF3B2,SGTA,SHC1,SIRT1,SLC10A1,SLC1A5,SLC22A5,SLC25A5,SLC25A6,SLC52A1,SLC52A2,SMARCA4,SMARCB1,SNAPIN,SND1,SNW1,SP1,SP100,SP110,SPEN,SRC,SRCAP,SRPK1,STAT1,STAT2,STOM,SUGT1,SUMO1,SUPT5H,SYK,SYNCRIP,TAF1,TAF4,TAP2,TARDBP,TBC1D20,TBK1,TBKBP1,TBP,TCP1,TFRC,TGFB1,THOC1,THOC2,THOC3,THOC5,THOC6,THOC7,TLN1,TMEM173,TMEM181,TNFRSF14,TNFRSF1A,TNFRSF4,TNIP1,TNPO1,TOP1,TP53,TP73,TPR,TREM1,TRIM22,TRIM23,TRIM25,TRIM5,TSC2,TSG101,TSPAN7,TYMS,TYRO3,UBAP1,UBC,UBE2I,UBE3A,UBN1,UBP1,UBR4,ULBP1,ULBP2,ULBP3,ULK2,UNG,USF1,USF2,USP6NL,USP7,UVRAG,VAC14,VAMP8,VAPA,VAPB,VCAM1,VCP,VIM,VPS18,VPS28,VPS37B,VPS37C,VPS37D,VPS4A,VPS4B,VRK2,VTA1,WAPL,WASF2,WWP1,WWP2,XPR1,XRCC4,XRCC5,XRCC6,YTHDC2,YWHAB,YWHAE,ZC3H12A,ZNF639,ZYX	TetrapodAncestor	78.7377
GO.Biological.Process	GO:0060071	Wnt.signaling.pathway,.planar.cell.polarity.pathway	485	1.662520e-83	2.147477e-79	4.427788e-82	1.402509e+0	AP2A1,AP2A2,AP2B1,AP2M1,AP2S1,ARHGEF19,ARRB2,CDC42,CELSR1,CELSR2,CLTC,DAAM1,DVL1,DVL3,FZD1,FZD2,FZD3,FZD4,FZD5,FZD6,FZD7,GPC4,GPC6,GRHL3,MAGI2,PARD6A,PFN1,PRICKLE1,PSMA2,PSMA3,PSMA4,PSMA8,PSMB1,PSMB10,PSMB11,PSMB3,PSMB4,PSMB5,PSMB7,PSMC1,PSMC2,PSMC3,PSMC4,PSMC5,PSMC6,PSMD1,PSMD10,PSMD11,PSMD13,PSMD2,PSMD3,PSMD4,PSMD5,PSMD7,PSMD8,PSMD9,PSME1,PSME2,PSME3,PSMF1,PTK7,RAC1,ROR2,RPS27A,RYK,SFRP1,SFRP2,SMURF1,SMURF2,TIAM1,UBC,VANGL1,VANGL2,WNT1,WNT11,WNT5A,WNT9B,ZNRF3	TetrapodAncestor	78.6681
GO.Biological.Process	GO:0046649	lymphocyte.activation	486	1.733721e-83	2.239447e-79	4.607916e-82	1.188151e+0	ABL1,ADA,ADGRG3,AICDA,AKAP17A,ANXA1,ATG5,ATM,ATP11C,AXL,AZI2,BAG6,BAK1,BANK1,BAX,BCL11B,BCL2,BCL3,BCL6,BLNK,BMX,BRAF,BST2,BTK,CARD11,CASP8,CBFB,CCL19,CCL21,CCND3,CCR6,CCR7,CCR9,CD151,CD180,CD1D,CD2,CD276,CD28,CD3D,CD3E,CD3G,CD40,CD6,CD7,CD74,CD79B,CD80,CD86,CD8A,CD8B,CDK6,CEBPG,CHD7,CHRNB2,CLCF1,CLEC4D,CLEC4E,CLEC7A,CMTM7,CORO1A,CR2,CTNNB1,CTPS1,CXADR,CXCR5,CYP26B1,DCAF1,DCLRE1C,DDOST,DLG1,DLL1,DLL4,DNAJA3,DOCK10,DOCK11,DOCK2,DOCK8,EBI3,EGR1,EIF2AK4,ELF4,EOMES,EP300,EPHB1,ERCC1,EXO1,EXOSC3,EXOSC6,F2RL1,FADD,FAS,FCER1G,FKBP1A,FKBP1B,FLT3LG,FOXN1,FOXP3,FUT7,FZD5,FZD7,FZD8,FZD9,GAPT,GATA3,GLI3,GON4L,GPR18,GPR183,HDAC4,HDAC5,HDAC9,HELLS,HHEX,HMGB1,HNF1A,HPRT1,HSH2D,IFNA1,IFNA10,IFNA13,IFNA14,IFNA16,IFNA17,IFNA2,IFNA21,IFNA4,IFNA5,IFNA6,IFNA7,IFNA8,IFNAR1,IFNB1,IFNE,IFNG,IFNK,IFNW1,IGBP1,IKZF1,IKZF3,IL10,IL12B,IL15,IL18,IL18R1,IL2,IL21R,IL23A,IL4,IL6,IL7,IL7R,IMPDH1,INS,IRF1,IRF4,ITFG2,ITGA4,ITGB1,ITGB2,ITK,ITM2A,ITPKB,JAG2,JAK3,JAML,JMJD6,KDELR1,KIF13B,KLF6,KLRF2,KLRK1,LAT,LAT2,LAX1,LCK,LCP1,LEF1,LEP,LEPR,LFNG,LGALS1,LIG4,LRRC8A,LY6D,LYL1,MAFB,MALT1,MEF2C,MERTK,MFNG,MLH1,MS4A1,MSH2,MSH6,MSN,MYH9,NBN,NCK1,NCK2,NCR1,NCR3,NCSTN,NFAM1,NHEJ1,NKX2-3,NLRC3,NOTCH2,NTRK1,ONECUT1,P2RX7,PATZ1,PIK3CD,PIK3CG,PIK3R1,PKNOX1,PLA2G2D,PLCG2,PLCL2,POLM,POU1F1,POU2F2,PPP3CA,PPP3CB,PRDX1,PREX1,PRKCB,PRKCD,PRKDC,PRLR,PSEN1,PSMB11,PTGER4,PTK2B,PTPN22,RAB27A,RAB29,RAG1,RAG2,RBPJ,RC3H1,RC3H2,RELB,RIPK2,RIPK3,RNF168,RNF8,RORC,RPS6,RSAD2,RUNX2,SATB1,SEMA4A,SHB,SKAP2,SLA2,SLAMF6,SLC11A1,SNX27,SOX4,SPI1,SPN,SRF,STAT6,SYK,TBK1,TCF3,TGFB1,THEMIS,TLR4,TNFRSF4,TNFSF14,TNFSF18,TNFSF8,TPD52,TREML2,TXLNA,TYRO3,ULBP1,ULBP2,ULBP3,VAV1,VCAM1,WNT1,WNT4,ZAP70,ZBTB1,ZFP36L1,ZFP36L2,ZFPM1,ZNF683	TetrapodAncestor	78.6499
GO.Biological.Process	GO:0046890	regulation.of.lipid.biosynthetic.process	487	1.942952e-83	2.509711e-79	5.153411e-82	1.298404e+0	ABCG1,ABHD6,ACACA,ACACB,ACADL,ACADVL,ACSL3,ADGRF5,ADIPOQ,ADIPOR1,ADIPOR2,ANXA1,APOA1,APOA4,APOA5,APOB,APOC1,APOC3,APOE,ATP1A1,AVP,AVPR1A,BMP2,BMP5,BMP6,BRCA1,C3,CCDC3,CDK4,CNEP1R1,CREB1,CREBL2,CYP27B1,CYP7A1,CYR61,DGAT2,DGKQ,DHCR7,DKK3,DKKL1,EGR1,EIF6,ELOVL6,ERLIN1,ERLIN2,FABP3,FASN,FBXW7,FDFT1,FDPS,FGF1,FGF19,FGFR4,FITM2,GPAM,GPER1,GPLD1,HMGCR,HMGCS1,HSD17B13,HTR2A,HTR2B,HTR2C,IFNG,IGFBP7,IL1B,INS,INSIG2,KPNB1,LDLR,LEP,LSS,MALRD1,MBTPS1,MBTPS2,MID1IP1,MLXIPL,MTOR,MVD,NFKB1,NFYA,NFYB,NFYC,NR1D1,NR1H2,NR1H3,NR1H4,NSMAF,ORMDL1,ORMDL2,ORMDL3,PDGFA,PDGFB,PLA2G6,PLIN5,PMVK,POR,PPARGC1A,PRKAA1,PRKAA2,PRKAG2,PRKCD,PROX1,REST,RGN,SC5D,SCARB1,SCD,SEC14L2,SERPINA12,SIK1,SIRT1,SIRT4,SLC27A1,SLC45A3,SMPD2,SMPD3,SNAI1,SNAI2,SOD1,SORBS1,SP1,SQLE,SREBF1,SREBF2,STAR,STARD4,THRSP,TM7SF2,TNF,TNFRSF1A,TRIB3,TSPO,VDR,WDTC1,WNT4,ZP3	TetrapodAncestor	78.6004
GO.Biological.Process	GO:0007568	aging	488	2.379618e-83	3.073753e-79	6.298673e-82	1.215400e+0	ABAT,ADA,ADRA1A,ADRB3,AGER,AGT,ALDH3A1,AMFR,AMH,APAF1,APEX1,APOD,APP,ARG1,ARNTL,ATM,ATP2B1,ATP8A2,ATR,AURKB,BAK1,BCL2,BCL2A1,BECN1,BGLAP,C2orf40,CACYBP,CALR,CANX,CARM1,CASP2,CASP9,CAT,CCL2,CD86,CDK1,CDKN1A,CDKN1C,CDKN2A,CHEK1,CHEK2,CISD2,CLDN1,CNR1,COL3A1,CREB1,CRYAB,CTGF,CTNNA1,CTSC,CYP1A1,DCN,DDC,DKK1,DLD,DNAJA3,DNMT3A,EDN1,EDNRB,EEF2,EIF2B5,ENDOG,ENG,EPO,ERCC1,ERCC2,ERO1A,FBXO4,FOS,FOXG1,FOXO4,GCLM,GHRHR,GLRX2,GNAO1,GNRH1,GRB2,GRM5,GSK3A,GSN,GSS,H2AFX,HAMP,HMGA2,HMGCR,HRAS,HTR2A,HTRA2,ID2,IDE,IGFBP2,IGFBP5,IL10,IL15,IL6,INPP5D,IRAK1,ITGB2,JUN,KAT6A,KCNE2,KCNMB1,KL,KRT14,KRT16,KRT25,KRT33B,KRT83,KRTAP4-5,KRTAP4-7,KRTAP4-8,KRTAP4-9,LITAF,LONP1,LOXL2,LRP1,LRRK2,MADCAM1,MAPK14,MAPKAPK5,MBD1,MBD2,MBD3,MIF,MME,MMP7,MNT,MPO,MSH2,MSH6,MTOR,NAPEPLD,NFKB2,NOX4,NPM1,NPY2R,NPY5R,NQO1,NSMCE2,NTRK1,NUDT1,NUP62,OGG1,OPA1,P2RY1,PAX2,PAX5,PCK1,PDE4D,PDGFRB,PENK,PICALM,PML,POLB,POU1F1,PPARGC1A,PRDM2,PRELP,PRKCD,PRMT6,PSEN1,PTEN,PTH1R,RAD54L,RELA,RETN,RGN,ROMO1,RPN2,RWDD1,SEC63,SERP1,SERPING1,SIRT1,SIRT3,SLC12A2,SLC1A2,SLC6A3,SMC5,SMC6,SNCA,SOD1,SOD2,SREBF1,SRF,SRR,TACR3,TBX2,TBX3,TERF2,TERT,TFCP2L1,TGFB1,TGFBR2,TH,TIMP1,TIMP2,TNFRSF1B,TP53,TP63,TPRA1,TRPC6,TSPO,TYMS,UCP2,UCP3,ULK3,VCAM1,WNT16,WRN,ZMIZ1,ZNF354A	TetrapodAncestor	78.5123
GO.Biological.Process	GO:0001952	regulation.of.cell-matrix.adhesion	489	2.661072e-83	3.437307e-79	7.029257e-82	1.300681e+0	ABL1,ACER2,ACVRL1,ADAM15,AJAP1,APOD,ARHGAP6,BCAS3,BCL2,BCL6,BST1,CAMSAP3,CASK,CCL21,CCL28,CCR7,CD36,CDH13,CDK6,CDKN2A,CIB1,CLASP1,CLASP2,COL16A1,CSF1,DAPK3,DDR1,DISC1,DLC1,DMTN,EFNA5,EMP2,EPB41L5,EPHA1,EPHA3,FERMT1,FMN1,GPM6B,GREM1,HRG,IQGAP1,MACF1,MINK1,MMP14,NF1,NF2,NINJ1,NRP1,ONECUT1,PHLDB2,PIK3R1,PLAU,PLEKHA2,PLET1,PPM1F,PRKCZ,PTEN,PTK2,PTK2B,PTPRJ,RAC1,RASA1,RCC2,RHOD,ROCK2,S100A10,SDC4,SEMA3E,SFRP1,SLC9A1,SRC,TEK,THBS1,THY1,UTRN,VEGFA,VEGFC,WNT4	TetrapodAncestor	78.4638
GO.Biological.Process	GO:0044774	mitotic.DNA.integrity.checkpoint	490	4.219733e-83	5.450629e-79	1.112373e-81	1.421608e+0	ATM,AURKA,BAX,BTG2,CARM1,CASP2,CCNB1,CCND1,CDC25C,CDK1,CDK2,CDKN1A,CDKN1B,CENPJ,CHEK2,CNOT1,CNOT10,CNOT11,CNOT2,CNOT3,CNOT4,CNOT6,CNOT6L,CNOT8,CRADD,DONSON,E2F1,E2F4,E2F7,E2F8,EME1,EME2,EP300,FANCI,FBXO31,FOXN3,FOXO4,GADD45A,GIGYF2,GML,GTSE1,HMGA2,HUS1,HUS1B,MDC1,MDM2,MDM4,MRE11,MRNIP,MSH2,MUC1,MUS81,NAE1,NBN,NEK11,NOP53,NPM1,ORAOV1,PCBP4,PCNA,PIDD1,PLAGL1,PLK2,PLK3,PML,PRKDC,PRMT1,RAD17,RAD9A,RFWD3,RGCC,RPA2,RPS27A,RPS27L,SETMAR,SFN,SOX4,TFDP2,TICRR,TNKS1BP1,TOP2A,TOPBP1,TP53,TP63,TP73,TRIAP1,UBC,XPC,ZNF385A,ZNF830	TetrapodAncestor	78.2636
GO.Biological.Process	GO:0002699	positive.regulation.of.immune.effector.process	491	5.083984e-83	6.566982e-79	1.337471e-81	1.299095e+0	ADGRE2,ADORA2B,ANKRD17,ANXA1,AP1G1,ARG1,ATAD5,BCL10,BTK,C12orf4,C3,C6,CADM1,CCL19,CCL2,CCR2,CD226,CD28,CD300A,CD36,CD40,CD46,CD74,CD80,CD86,CLCF1,CRTAM,DDX60,EXOSC3,EXOSC6,F2RL1,FADD,FAM49B,FCER1G,FCER2,FER,FES,FFAR2,FFAR3,FGR,FOXF1,FOXP3,FZD5,GAB2,GATA2,GATA3,GPRC5B,HLX,HMOX1,IFNG,IL12A,IL12B,IL12RB1,IL13,IL13RA2,IL18,IL18RAP,IL1B,IL2,IL21,IL23A,IL23R,IL33,IL4,IL5,IL6,ITGAM,ITGB2,KARS,KLRK1,LBP,LGALS9,LYN,MALT1,MAP3K7,MAPK14,MAPK3,MIF,MLH1,MSH2,MSH6,MYB,MYO18A,MZB1,NCR3,NECTIN2,NR4A3,NSD2,P2RX7,PAXIP1,PDPK1,PGC,PHB,PRKCZ,PTAFR,RAC2,RAP1A,RAPGEF1,RARA,RASGRP1,RBP4,RIF1,RIPK2,RSAD2,SASH3,SEMA7A,SH2D1A,SH2D1B,SHB,SLAMF6,SNX4,SOCS5,SPON2,STAT6,STX4,STX7,STXBP1,STXBP2,STYK1,SYK,TFRC,TGFB1,TLR4,TLR9,TNF,TNFRSF14,TNFRSF4,TNFSF13,TRAF2,TRAF6,TRIM6,UNG,VAMP8,VAV1,WNT5A,XBP1,XCL1,ZBTB1,ZP3	TetrapodAncestor	78.1826
GO.Biological.Process	GO:0001885	endothelial.cell.development	492	5.169199e-83	6.677054e-79	1.357125e-81	1.513992e+0	AFDN,ARHGEF26,CCM2,CLDN1,COL18A1,CTNNB1,ENG,EZR,F11R,F2RL1,GSTM3,HAPLN2,HEG1,ID1,MARVELD2,MET,MSN,MYADM,NOTCH4,PDE2A,PDE4D,PPP1R16B,PTPRS,RAP1A,RAP1B,RAP2C,RAPGEF1,RAPGEF2,RAPGEF3,RDX,SOX18,STC1,TJP1,TJP2,TNMD,VEZF1,WNT7A,WNT7B	TetrapodAncestor	78.1754
GO.Biological.Process	GO:0061041	regulation.of.wound.healing	493	5.227283e-83	6.752081e-79	1.369591e-81	1.277731e+0	ABAT,ABCC8,ADAMTS18,ADRA2A,AGER,AJAP1,ANO6,ANXA1,APOE,APOH,ASIC2,C1QTNF1,CASK,CAV1,CCL2,CD109,CD34,CD36,CD9,CLASP1,CLASP2,CLEC4M,CPB2,CRK,DMTN,DUSP10,EDN1,ENPP4,ENSG00000255439,F11,F12,F2,F2R,F2RL1,F3,F7,FAM46A,FCER1G,FGF2,FGG,FOXA2,FOXC2,GJA1,GP1BA,HBEGF,HMGB1,HMGCR,HPSE,HRAS,HRG,INSL3,KANK1,KLKB1,KNG1,KRT1,LBH,LYN,MTOR,MYLK,MYOD1,NOS3,PDGFA,PDGFB,PDPN,PHLDB2,PLAT,PLAU,PLEK,PLG,PLPP3,PPARD,PRKCA,PRKCD,PRKCE,PRKCQ,PRKG1,PROC,PROS1,PROZ,PTEN,REG3A,REG3G,RREB1,SCARA5,SELP,SERPINB2,SERPINC1,SERPINE2,SERPING1,SOX15,SPAAR,SRSF6,STAB2,STXBP5,SYK,TBXA2R,TC2N,TEC,TGFBR2,THBD,THBS1,TLR4,TMPRSS6,TNFAIP3,TNFRSF12A,TSPAN8,TXK,UBASH3B,USF1,VAV2,VIL1,VPS33B,VTN,WFDC1,WNT4,XBP1	TetrapodAncestor	78.1706
GO.Biological.Process	GO:0002687	positive.regulation.of.leukocyte.migration	494	6.240999e-83	8.061498e-79	1.631882e-81	1.372023e+0	ADAM8,AIF1,ANO6,APP,BDKRB1,C1QBP,C3AR1,CALR,CAMK1D,CCL1,CCL19,CCL2,CCL21,CCL3,CCL4,CCL5,CCL7,CCL8,CCR1,CCR2,CCR6,CCR7,CD74,CMKLR1,CREB3,CSF1,CXCL1,CXCL10,CXCL11,CXCL13,CXCL14,CXCL2,CXCL3,CXCL5,CXCL6,CXCL8,CXCL9,DAPK2,DOCK8,EDN1,EDN2,EDN3,F2RL1,F7,FADD,GAS6,GPSM3,HMGB1,IL12A,IL1A,IL1R1,IL23A,IL4,IL6,IL6R,ITGA2,ITGA2B,ITGA4,KARS,KITLG,LBP,LGALS3,LGALS9,MADCAM1,MAPK14,MAPK3,MIA3,MMP14,MOSPD2,NCKAP1L,PDGFD,PF4,PF4V1,PLA2G7,PLVAP,PPBP,PTAFR,PTK2B,PYCARD,RAC1,RAC2,RARRES2,RIPOR2,S100A14,S100A7,SELENOK,SELP,TGFB1,THBS1,THBS4,THY1,TIRAP,TNF,TNFRSF14,TNFRSF18,TNFSF14,TNFSF18,VEGFA,VEGFB,VEGFC,VEGFD,WNT5A,XCL1,ZNF580,ZP3	TetrapodAncestor	78.0936
GO.Biological.Process	GO:0051017	actin.filament.bundle.assembly	495	6.310341e-83	8.151067e-79	1.646680e-81	1.546912e+0	ACTN1,ACTN4,ADD1,AIF1,ARRB1,BAIAP2L2,CDC42,CORO1B,CUL3,DMTN,DPYSL3,EPS8,ESPN,ESPNL,EZR,FMN2,FSCN1,FSCN3,HSP90B1,ITGB5,KCTD13,LCP1,LIMA1,MARCKS,MYO1B,NEDD9,PAWR,PDXP,PHACTR1,PLS1,PLS3,PTK2B,RHOD,SORBS1,SPIRE1,SPIRE2,SRC,SRF,TNFAIP1,USH1C,ZYX	TetrapodAncestor	78.0888
GO.Biological.Process	GO:0010035	response.to.inorganic.substance	496	9.102273e-83	1.175741e-78	2.370445e-81	1.167360e+0	AANAT,ABAT,ABCB4,ABCC2,ABCC8,ABL1,ACER1,ACO1,ADA,ADAM9,ADAMTS13,ADCY10,ADD1,ADNP,ADPRHL2,AHCYL1,AIFM1,AKR1B1,ALAD,ALG2,ALOX15,ALOX5AP,ANK3,ANKZF1,ANXA1,AOC1,APEX1,APOA4,APOB,APOBEC1,APP,APTX,AQP1,AQP2,AQP3,AREG,ARG1,ARL13B,ASCL1,ATF4,ATIC,ATP13A2,ATP2B4,ATP7B,AVPR1A,AXL,BAD,BAK1,BAP1,BCL2,BECN1,BGLAP,BMP6,BNIP3,BRAF,BSG,C1QA,CA2,CACNA1G,CACNA1H,CACYBP,CALM1,CALM2,CALM3,CALR,CAMK2D,CARF,CASP3,CASP8,CASP9,CASQ2,CASR,CAT,CAV1,CBX8,CCL19,CCNA2,CCNB1,CCND1,CCR7,CD14,CD86,CD9,CDH1,CDK1,CDK2,CDK4,CDKN1B,CEBPA,CFLAR,CHUK,CLDN1,CNGA3,COL18A1,COL1A1,CPNE2,CPNE3,CPNE6,CPNE7,CPOX,CPS1,CREB1,CRHBP,CRIP1,CRK,CRYAB,CUTA,CYB5A,CYBB,CYP11B1,CYP11B2,CYP1A1,CYP1A2,CYP1B1,D2HGDH,DAXX,DDX11,DMTN,DNM2,DNMT3A,DPEP1,DRD2,DUSP1,ECT2,EDN1,EEF2,EEF2K,EGFR,EGLN1,EIF2AK3,EIF2B5,EIF4A3,ENDOG,ENSG00000214732,ENTPD6,ERCC1,ERCC6,ETS1,EZH2,FABP1,FABP4,FANCC,FAS,FBP1,FGF23,FGG,FIBIN,FIS1,FKBP1A,FKBP1B,FMR1,FNTB,FOS,FOSB,FOSL1,FOXO1,FSTL3,FUS,FXN,G6PD,GART,GDI1,GGH,GIP,GIPR,GLRA1,GLRA2,GLRX2,GNAO1,GNRH1,GPHN,GPLD1,GSK3A,GSN,GSS,GUCY1B3,HAAO,HAMP,HBA1,HBA2,HBB,HDAC2,HIF1A,HMGCS1,HMOX1,HNRNPD,HOMER1,HP,HPCA,HSF1,HSPA5,IGFBP2,IL18BP,IL18RAP,IL1A,IL4,IL6,IQGAP1,ITPKB,ITPR3,JUN,JUNB,KCNA1,KCNA5,KCNC1,KCNC2,KCNH1,KCNK3,KCNMA1,KCNMB1,KCNMB2,KCNMB3,KCNMB4,KDM6B,KHK,KLF2,KLF4,KPNA4,KRT14,LCN2,LDHA,LIG4,LONP1,LOXL2,LRP11,LRRK2,MAOB,MAP1LC3A,MAP3K5,MAPK1,MAPK3,MAPK8,MAPK9,MB,MDM2,MEF2A,MEF2C,MMP3,MMP9,MPO,MTF1,MYB,MYOG,NCF1,NDRG1,NEDD4L,NEFL,NET1,NFATC4,NLGN1,NOS3,NPC1,NQO1,NR4A3,NSMCE3,NTRK1,NUDT1,OGG1,OTC,P2RX7,PAM,PARK7,PARP1,PAX2,PCGF2,PCNA,PDCD10,PDCD6,PDGFD,PDGFRB,PEF1,PENK,PGAM2,PHEX,PINK1,PKD2,PKLR,PLEKHA1,PLN,PPARGC1A,PPIF,PPP1R15B,PPP2CB,PPP3CA,PPP5C,PRDX1,PRDX2,PRDX3,PRKAA1,PRKCD,PRKN,PTCH1,PTEN,PTGES,PTH,PTK2B,QDPR,RAD51,RASGRP2,RELA,RPS3,RYR1,RYR2,RYR3,S100A13,S100A16,S100A8,SCGB1A1,SCN5A,SELENOM,SETX,SIPA1,SIRT1,SLC25A23,SLC25A24,SLC26A5,SLC30A1,SLC30A10,SLC30A2,SLC30A4,SLC30A5,SLC30A6,SLC30A7,SLC30A8,SLC34A1,SLC39A13,SLC40A1,SLC41A1,SLC6A3,SLC8A1,SLFN14,SNCA,SNCB,SOD1,SOD2,SOD3,SORD,SPAG16,SPIDR,SRC,STAR,STAT6,STIM1,STK24,STK26,SUMO1,SYT1,TAT,TERT,TESMIN,TF,TFAP2A,TFAP2B,TFF1,TFR2,TH,THBS1,TIGAR,TIMELESS,TNFAIP3,TNFRSF11B,TNNC1,TNNT2,TPH2,TRAF2,TRPA1,TRPC1,TRPC3,TRPC6,TRPM2,TRPV6,TSHB,TSPO,TTN,TXNIP,TXNRD1,UBE3A,UCP2,UCP3,VCAM1,WNK1,WNT10B,WNT5A,XRCC4,ZACN,ZC3H12A,ZNF277,ZNF580,ZNF658	TetrapodAncestor	77.9297
GO.Biological.Process	GO:0043547	positive.regulation.of.GTPase.activity	497	1.037137e-82	1.339670e-78	2.695513e-81	1.164229e+0	A2M,ABR,ACAP2,ACAP3,ADAP1,ADAP2,ADCYAP1,ADGRB3,AFDN,AGAP1,AGAP2,AGAP3,AGAP4,AGAP9,AGFG2,AGRN,AKT2,ALDH1A1,ALS2,ALS2CL,ANKRD27,APC2,ARAP1,ARAP2,ARAP3,ARFGAP2,ARFGAP3,ARHGAP1,ARHGAP11A,ARHGAP12,ARHGAP15,ARHGAP17,ARHGAP18,ARHGAP19,ARHGAP20,ARHGAP21,ARHGAP22,ARHGAP23,ARHGAP24,ARHGAP25,ARHGAP26,ARHGAP27,ARHGAP28,ARHGAP29,ARHGAP30,ARHGAP31,ARHGAP32,ARHGAP33,ARHGAP35,ARHGAP39,ARHGAP4,ARHGAP42,ARHGAP44,ARHGAP5,ARHGAP6,ARHGAP8,ARHGDIA,ARHGDIB,ARHGEF1,ARHGEF11,ARHGEF12,ARHGEF16,ARHGEF19,ARHGEF37,ARHGEF7,ARRB1,ASAP1,ASAP3,AXIN2,BCAS3,BCR,C15orf62,CAV2,CCDC125,CCL1,CCL11,CCL13,CCL14,CCL15,CCL15-CCL14,CCL16,CCL17,CCL18,CCL19,CCL2,CCL21,CCL22,CCL23,CCL3,CCL3L3,CCL4,CCL4L2,CCL5,CCL7,CCL8,CCR7,CD40,CDC42EP1,CDC42EP2,CDC42EP3,CDC42EP4,CDC42EP5,CDKL5,CHM,CHML,CHN2,CX3CL1,CXCL13,DAB2IP,DENND1A,DENND1B,DEPDC1,DEPDC1B,DEPDC5,DLC1,DNM1L,DNMBP,DOCK10,DOCK11,DOCK2,DOCK4,DOCK8,DOCK9,DVL3,ECT2,ELMOD1,ELMOD2,EPHA1,EPHA2,ERBB2,ERRFI1,EVI5L,EZH2,F11R,F2R,F2RL1,FAM13A,FAM13B,FOXJ1,FZD10,GAPVD1,GARNL3,GDI1,GDI2,GNAO1,GNAQ,GNB5,GPR65,GRHL3,HACD3,HRAS,HTR2B,INPP5B,IQGAP1,ITGB1,JUN,KALRN,LARS,LLGL2,LRRK2,MTSS1L,MYO9A,MYO9B,NCKAP1L,NDEL1,NET1,NF1,NPRL2,NPRL3,NRP1,NTF3,NTRK1,NTRK3,OCRL,OPHN1,PGAM5,PICALM,PIK3R2,PIN1,PIP5K1A,PLCB1,PLEKHG4,PLEKHG6,PLXNB1,PREB,PREX1,PTK2B,RAB3GAP1,RAB3GAP2,RABEP1,RABEP2,RABGAP1,RABGAP1L,RACGAP1,RALBP1,RALGAPB,RANBP2,RANBP3,RANBP3L,RAP1A,RAP1GAP,RAP1GAP2,RAP1GDS1,RAPGEF1,RAPGEF2,RAPGEF3,RASA1,RASA2,RASA3,RASA4B,RASAL1,RASAL2,RASAL3,RASGEF1B,RASGRF1,RASGRP1,RASGRP2,RCC2,RGL3,RGN,RGP1,RGPD4,RGS1,RGS10,RGS13,RGS14,RGS16,RGS17,RGS18,RGS19,RGS2,RGS20,RGS21,RGS3,RGS4,RGS5,RGS6,RGS7,RGS8,RGS9,RGSL1,RHOG,RIC1,RIC8A,RIC8B,RIN2,RIN3,RINL,RP2,RSU1,RTN4R,RUNDC1,S100A10,S1PR1,SCRIB,SEMA4D,SFRP1,SGSM1,SGSM2,SGSM3,SH3BP1,SIPA1,SIPA1L1,SIPA1L2,SIPA1L3,SMAP1,SMAP2,SNX13,SNX18,SNX9,SOS1,SRGAP1,SRGAP2,SRGAP2B,SRGAP2C,SRGAP3,STARD13,STARD8,STXBP5,STXBP5L,SYDE1,SYDE2,SYNGAP1,TAGAP,TAX1BP3,TBC1D1,TBC1D10A,TBC1D10C,TBC1D14,TBC1D15,TBC1D16,TBC1D17,TBC1D19,TBC1D20,TBC1D21,TBC1D22A,TBC1D22B,TBC1D24,TBC1D26,TBC1D28,TBC1D2B,TBC1D3,TBC1D30,TBC1D3B,TBC1D3F,TBC1D3K,TBC1D4,TBC1D5,TBC1D7,TBC1D8,TBC1D8B,TBC1D9,TBC1D9B,TBCD,TBCK,THY1,TIAM1,TIAM2,TRIP10,TSC2,USP6NL,VAV1,VAV3,VPS9D1,WNT11,WNT4,WNT5A,XCL1,XCL2	TetrapodAncestor	77.873
GO.Biological.Process	GO:0007010	cytoskeleton.organization	498	1.884146e-82	2.433751e-78	4.887051e-81	1.111769e+0	ABI1,ABI2,ABL1,ABLIM1,ABLIM2,ABLIM3,ABR,ACTL6B,ACTL7B,ACTN1,ACTN4,ACTR2,ACTR3,ACTR3B,ACTR3C,ADD1,ADRA2A,AGRN,AIF1,AJUBA,ALDOA,ALKBH4,AMOT,ANK1,ANK2,ANK3,ANKRD1,ANLN,ANTXR1,ANXA1,APC2,APOE,AQP1,ARAP1,ARAP3,ARC,ARF1,ARF6,ARHGAP12,ARHGAP25,ARHGAP26,ARHGAP35,ARHGAP4,ARHGAP6,ARHGEF11,ARHGEF17,ARHGEF2,ARL2,ARPC1A,ARPC1B,ARPC2,ARPC4,ARPC4-TTLL3,ARPC5,ARRB1,ASPM,ATP8A2,ATXN3,AUNIP,AURKA,AURKB,AURKC,AUTS2,AVIL,BAIAP2L2,BBS4,BCAR1,BCAS3,BCL2,BCL6,BCR,BFSP1,BFSP2,BICD1,BICD2,BIN3,BIRC5,BMP10,BRCA1,BRSK1,BRSK2,BRWD1,BRWD3,C11orf63,C21orf2,C2CD3,CALR,CAMSAP1,CAMSAP3,CAP1,CAP2,CAPN10,CAPN6,CAPZB,CARMIL1,CARMIL2,CASQ1,CASQ2,CATIP,CAV3,CAVIN3,CCDC103,CCDC114,CCDC120,CCDC13,CCDC151,CCDC155,CCDC183,CCDC40,CCDC6,CCDC68,CCDC69,CCDC8,CCDC88A,CCDC88B,CCDC88C,CCL11,CCL13,CCL2,CCL3,CCL7,CCNB1,CCP110,CCSER2,CD2AP,CDC14A,CDC14B,CDC20,CDC42,CDC42BPA,CDC42BPB,CDC42BPG,CDC42EP2,CDK1,CDK2,CDK5,CDK5RAP2,CECR2,CENPA,CENPE,CENPJ,CEP120,CEP126,CEP19,CEP192,CEP250,CEP350,CEP57,CEP63,CEP68,CEP72,CETN3,CFAP100,CFAP157,CFAP206,CFAP73,CFL1,CFL2,CFLAR,CHD3,CHEK2,CHP1,CIB1,CKAP5,CLASP1,CLASP2,CLRN1,CNN1,CNN3,CNTLN,CNTN2,CNTROB,COBL,CORO1A,CORO1B,CORO2B,CORO6,CRIPT,CRMP1,CROCC,CRYAB,CSNK1A1,CSNK1D,CSRP3,CTNNA1,CTNNA2,CTNNB1,CTTN,CUL3,CUL7,CUL9,CXADR,CXCL1,CYLC1,CYTH2,DAAM1,DAAM2,DBN1,DCTN1,DES,DEUP1,DIAPH1,DIAPH2,DIAPH3,DISC1,DLC1,DLG1,DMD,DMTN,DNAAF1,DNAAF2,DNAAF3,DNAAF5,DNAH1,DNAH3,DNAH5,DNAH7,DNAH8,DNAI1,DNAI2,DNAJB13,DNAJB6,DNAL1,DOCK2,DPYSL2,DPYSL3,DRC1,DSP,DST,DSTN,DTNBP1,DVL1,DYNC1H1,DYNC1LI1,DYNC1LI2,DYNLT1,EFHC1,EHD2,ELMO1,ELMO2,EML1,EMP2,ENSG00000198211,ENSG00000259132,ENSG00000284292,EPB41,EPB41L1,EPB41L2,EPB41L3,EPB41L4A,EPB41L4B,EPB41L5,EPS8,ESPL1,ESPN,ESPNL,EVL,EYA1,EZR,F11R,FAM83H,FAT1,FBXO5,FER,FES,FGD1,FGD2,FGD3,FGD4,FGD5,FGF10,FGF13,FGF7,FGFR1OP,FHL3,FHOD3,FITM2,FLII,FLNA,FLNB,FMN1,FMN2,FMNL1,FMNL2,FMNL3,FOXJ1,FRMD3,FRMD5,FRMD6,FRY,FRYL,FSCN1,FSCN3,FTCD,GAB1,GADD45A,GAN,GAPDH,GAS2L3,GAS8,GCC2,GDPD2,GFAP,GHSR,GOLGA2,GPR35,GPR65,GSN,HAUS2,HAUS3,HAUS4,HAUS6,HAUS7,HAUS8,HCLS1,HDAC3,HDGFL3,HEPACAM2,HIP1,HOOK1,HOOK2,HOOK3,HSP90B1,HTT,HYDIN,IFT172,IGSF22,IKBKB,INF2,INO80,INPP5K,INSRR,INTS13,IQSEC2,IQSEC3,ITGB1,ITGB5,ITPKA,JAK2,JMY,JUP,KCTD13,KIAA0753,KIF11,KIF18A,KIF18B,KIF19,KIF20A,KIF24,KIF25,KIF2A,KIF2B,KIF2C,KIF3A,KIF3B,KIF4A,KIF4B,KIFC1,KISS1,KLHL1,KLHL17,KLHL20,KLHL24,KNSTRN,KPNB1,KPTN,KRAS,KRT13,KRT14,KRT15,KRT16,KRT17,KRT19,KRT2,KRT20,KRT25,KRT31,KRT5,KRT6A,KRT6B,KRT6C,KRT71,KRT74,KRT76,KRT84,KRT9,LAMA5,LARP4,LCP1,LDB3,LIMA1,LIMCH1,LIMD1,LIMK1,LMNA,LMOD1,LMOD3,LOR,LRGUK,LRRC6,LURAP1,MAD2L2,MAEA,MAP10,MAP1B,MAP1S,MAP2,MAP4,MAP6,MAP6D1,MAP7,MAP7D1,MAP7D2,MAP9,MAPKAP1,MAPT,MARCKS,MARK1,MARK2,MARK4,MAST1,MAST2,MAST3,MCPH1,MECP2,MEF2A,MICAL1,MICAL3,MID1,MINK1,MKLN1,MLH1,MOB2,MOS,MSN,MSRB2,MTM1,MTSS1,MYBL2,MYBPC1,MYBPC2,MYBPC3,MYBPH,MYH10,MYH14,MYH3,MYH6,MYH9,MYLK3,MYO18A,MYO1B,MYOM2,MYOM3,MYOZ3,MYPN,MZT1,NCK1,NCK2,NCKAP1L,NCKAP5L,NDC80,NDEL1,NEBL,NECTIN2,NEDD9,NEFH,NEFL,NEFM,NEK6,NEK7,NEURL1,NF1,NF2,NISCH,NKX2-5,NLGN1,NPHP1,NPHP4,NPHS2,NPM1,NRP1,NTMT1,NUAK2,NUP62,NUSAP1,OBSCN,ODF2,OPHN1,PACSIN2,PADI6,PAFAH1B1,PAK1,PAK2,PAK4,PAK5,PALLD,PALM,PARD6A,PARVB,PARVG,PAWR,PCLAF,PCLO,PCM1,PCNT,PDCD6IP,PDGFA,PDGFRB,PDLIM3,PDLIM4,PDLIM7,PDPK1,PDXP,PDZD8,PEX14,PFDN1,PFN1,PFN2,PFN3,PHACTR1,PHACTR4,PHIP,PHLDB2,PIH1D3,PIP5K1A,PIP5K1C,PKD2,PKP1,PKP2,PLA2G1B,PLA2G3,PLCE1,PLD2,PLEK,PLEK2,PLK1,PLK2,PLK3,PLK4,PLS1,PLS3,POC1A,POF1B,PPARGC1B,PPL,PPP1R12A,PPP2R3C,PRC1,PREX1,PRKAR1A,PRKCI,PRKCZ,PRKG1,PROX1,PRPF40A,PSTPIP2,PTK2,PTK2B,PTK7,PTPA,PTPN1,PYY,RAB13,RAC1,RAC2,RAC3,RACGAP1,RAF1,RALA,RANBP2,RANBP3,RANBP3L,RANBP9,RAP1GDS1,RAP2A,RCC1,RFLNA,RFLNB,RGPD4,RGS14,RHOD,RHOG,RHOJ,RHOQ,RHOU,RICTOR,RND1,RND3,ROCK2,RP1,RP1L1,RPS3,RSPH1,RSPH4A,RSPH9,RTKN,RUFY3,S1PR1,SAPCD2,SASS6,SBDS,SBK2,SCIN,SDAD1,SDCBP,SEMA6A,SETD2,SGO1,SH3BP1,SH3KBP1,SHANK1,SHC1,SHROOM4,SIPA1,SIPA1L1,SIPA1L3,SLAIN2,SLC16A1,SLC9A3R1,SOD1,SON,SORBS1,SORBS2,SORBS3,SOX9,SPAG16,SPAG17,SPAG4,SPAST,SPDL1,SPIRE1,SPIRE2,SPRY1,SPRY2,SPTB,SPTBN2,SPTBN5,SRC,SRF,SRGAP2,SRGAP2C,SS18,SSH2,STARD9,STIL,STMN1,STMN4,STRIP1,STRIP2,SUN1,SUN2,SUN3,SUN5,SVIL,SYNE1,SYNE2,SYNE3,SYNM,TACC1,TACC2,TACC3,TAOK2,TBCK,TEKT2,TESK2,THY1,TLN1,TMEM141,TMOD1,TMOD2,TMOD3,TMOD4,TMSB4Y,TNF,TNFAIP1,TNIK,TNKS,TNNT2,TNXB,TOGARAM1,TOR1A,TPGS1,TPM2,TPM3,TPM4,TPPP,TPPP3,TPX2,TRDN,TRIM32,TRIM36,TRIM46,TRIOBP,TRIP10,TRPM7,TSPAN32,TTC17,TTK,TTL,TTLL1,TTLL3,TTN,TUBA1A,TUBA1B,TUBA1C,TUBA3C,TUBA4B,TUBA8,TUBAL3,TUBB,TUBB1,TUBB2A,TUBB2B,TUBB3,TUBB4A,TUBB4B,TUBB6,TUBE1,TUBGCP2,TUBGCP3,TUBGCP4,TUBGCP5,TUBGCP6,UGT8,ULK4,USH1C,UVRAG,UXT,VASP,VIL1,VILL,VIM,VPS54,WASF2,WASHC5,WDR1,WDR62,XIRP1,XRCC2,YEATS4,ZMYM2,ZMYM4,ZMYM5,ZMYM6,ZNF135,ZNF207,ZPR1,ZW10,ZYX	TetrapodAncestor	77.6137
GO.Biological.Process	GO:0010508	positive.regulation.of.autophagy	499	3.245921e-82	4.192756e-78	8.402317e-81	1.357341e+0	ADRB2,AMBRA1,ATG14,ATPIF1,BAD,BECN1,BNIP3,BNIP3L,C9orf72,CAMKK2,CLEC16A,DAPK1,DCN,DHRSX,EIF2AK4,EPM2A,FBXO7,FLCN,FOXO1,FYCO1,GBA,HIF1A,HMOX1,HTT,IFNG,IKBKG,IRGM,KIAA1324,LACRT,LARP1,LRRK2,LRSAM1,MAP3K7,MAPK3,MEFV,MID2,MTDH,MUL1,NOD1,NPRL2,OPTN,PAFAH1B2,PARK7,PIM2,PINK1,PIP4K2A,PIP4K2B,PIP4K2C,PLEKHF1,PLK2,PLK3,PRKAA1,PRKAA2,PRKD1,PRKN,RAB12,RAB3GAP1,RAB3GAP2,RALB,RIPK2,RNF152,SCOC,SESN2,SH3BP4,SH3GLB1,SIRT1,SMCR8,SPTLC1,SPTLC2,SUPT5H,SVIP,TBK1,TFEB,TICAM1,TMEM59,TP53INP1,TP53INP2,TPCN1,TRIM13,TRIM21,TRIM22,TRIM8,TSC2,UVRAG,ZC3H12A	TetrapodAncestor	77.3775
GO.Biological.Process	GO:2000573	positive.regulation.of.DNA.biosynthetic.process	500	3.537479e-82	4.569362e-78	9.138723e-81	1.410089e+0	ACD,ARRB2,ATM,ATR,AURKB,CCT2,CCT3,CCT4,CCT5,CCT6A,CCT7,CCT8,CHTF18,CTNNB1,DKC1,DSCC1,FBXO4,FGFR4,GREM1,GRHL2,HGF,HMBOX1,HNRNPA2B1,HNRNPD,HSP90AB1,KLF4,MAP2K7,MAP3K4,MAPK1,MAPK15,MAPK3,MAPKAPK5,MYC,NAF1,NEK7,NOX4,NVL,PAK3,PARM1,PARN,PDGFB,PDGFRB,PKIB,PNKP,POT1,PRKCQ,PRKD2,PTK2B,RFC2,RFC3,RFC4,RGCC,SRC,TCP1,TNKS,TNKS2,WRAP53,XRCC5	TetrapodAncestor	77.3401
#.GO.Biological.Process	12917	1	1000	TetrapodAncestor	inf